Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	CTP binding	HSP90AA1 HSP90AB1	1.67e-05	2	82	2	GO:0002135
GeneOntologyMolecularFunction	sulfonylurea receptor binding	HSP90AA1 HSP90AB1	4.98e-05	3	82	2	GO:0017098
GeneOntologyMolecularFunction	calcium ion binding	MYOF CALB2 CALU RET CDH1 TENM2 RPH3A CDH12 SVEP1 NCS1 RYR1 RYR2	5.29e-05	749	82	12	GO:0005509
GeneOntologyMolecularFunction	UTP binding	HSP90AA1 HSP90AB1	9.94e-05	4	82	2	GO:0002134
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR2	9.94e-05	4	82	2	GO:0005219
GeneOntologyMolecularFunction	pyrimidine ribonucleotide binding	HSP90AA1 HSP90AB1	1.65e-04	5	82	2	GO:0032557
GeneOntologyMolecularFunction	dATP binding	HSP90AA1 HSP90AB1	1.65e-04	5	82	2	GO:0032564
GeneOntologyMolecularFunction	adenyl deoxyribonucleotide binding	HSP90AA1 HSP90AB1	2.47e-04	6	82	2	GO:0032558
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR2	2.47e-04	6	82	2	GO:0048763
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	GRIA3 RYR1 RYR2	2.76e-04	31	82	3	GO:0099604
GeneOntologyMolecularFunction	purine deoxyribonucleotide binding	HSP90AA1 HSP90AB1	3.45e-04	7	82	2	GO:0032554
GeneOntologyMolecularFunction	TPR domain binding	HSP90AA1 HSP90AB1	4.59e-04	8	82	2	GO:0030911
GeneOntologyMolecularFunction	disordered domain specific binding	RRM1 HSP90AA1 HSP90AB1	5.48e-04	39	82	3	GO:0097718
GeneOntologyMolecularFunction	deoxyribonucleotide binding	HSP90AA1 HSP90AB1	5.89e-04	9	82	2	GO:0032552
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC30A7 SCN8A GRIA3 CPOX ATP1A4 NCS1 RYR1 RYR2	6.43e-04	465	82	8	GO:0046873
GeneOntologyMolecularFunction	nitric-oxide synthase regulator activity	HSP90AA1 HSP90AB1	7.34e-04	10	82	2	GO:0030235
GeneOntologyMolecularFunction	P-type sodium transporter activity	CPOX ATP1A4	7.34e-04	10	82	2	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	CPOX ATP1A4	7.34e-04	10	82	2	GO:0005391
GeneOntologyMolecularFunction	pyrimidine nucleotide binding	HSP90AA1 HSP90AB1	8.94e-04	11	82	2	GO:0019103
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	CPOX ATP1A4	8.94e-04	11	82	2	GO:0008556
GeneOntologyMolecularFunction	calcium channel activity	GRIA3 NCS1 RYR1 RYR2	1.97e-03	129	82	4	GO:0005262
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR1 RYR2	2.44e-03	18	82	2	GO:0015278
GeneOntologyMolecularFunction	cadherin binding	CAPZB LARP1 DBN1 CDH1 CDH12 HSP90AB1	2.72e-03	339	82	6	GO:0045296
GeneOntologyMolecularFunction	ubiquitin-modified protein reader activity	IDE USP15	3.02e-03	20	82	2	GO:0140036
GeneOntologyMolecularFunction	cell adhesion molecule binding	CAPZB LARP1 DBN1 CDH1 TENM2 CDH12 SVEP1 HSP90AB1	3.18e-03	599	82	8	GO:0050839
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	GRIA3 NCS1 RYR1 RYR2	3.48e-03	151	82	4	GO:0015085
GeneOntologyMolecularFunction	DNA polymerase binding	HSP90AA1 HSP90AB1	3.99e-03	23	82	2	GO:0070182
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC30A7 SCN8A GRIA3 CPOX ATP1A4 NCS1 RYR1 RYR2	4.19e-03	627	82	8	GO:0022890
GeneOntologyCellularComponent	distal axon	CALB2 GRIA3 DBN1 CDH1 TENM2 NCS1 GOT1 HSP90AA1 HSP90AB1	4.67e-05	435	81	9	GO:0150034
GeneOntologyCellularComponent	dendrite	CALB2 SCN8A CAPZB PI4K2A GRIA3 RET DBN1 TENM2 RPH3A NCS1 HSP90AA1 HSP90AB1	1.11e-04	858	81	12	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CALB2 SCN8A CAPZB PI4K2A GRIA3 RET DBN1 TENM2 RPH3A NCS1 HSP90AA1 HSP90AB1	1.13e-04	860	81	12	GO:0097447
GeneOntologyCellularComponent	extrinsic component of plasma membrane	CDH1 TENM2 CDH12 RYR1 RYR2	1.93e-04	137	81	5	GO:0019897
GeneOntologyCellularComponent	cluster of actin-based cell projections	CALB2 CLTRN CAPZB TSPEAR HSP90AA1 HSP90AB1	2.30e-04	223	81	6	GO:0098862
GeneOntologyCellularComponent	extrinsic component of membrane	CDH1 TENM2 RPH3A CDH12 RYR1 RYR2	2.71e-04	230	81	6	GO:0019898
GeneOntologyCellularComponent	sarcoplasmic reticulum	SLC30A7 CALU RYR1 RYR2	3.81e-04	88	81	4	GO:0016529
GeneOntologyCellularComponent	site of polarized growth	PI4K2A FRYL DBN1 TENM2 HSP90AA1 HSP90AB1	4.50e-04	253	81	6	GO:0030427
GeneOntologyCellularComponent	parallel fiber to Purkinje cell synapse	CALB2 SCN8A GRIA3	6.19e-04	43	81	3	GO:0098688
GeneOntologyCellularComponent	axon	CALB2 SCN8A GRIA3 RET DBN1 CDH1 TENM2 NCS1 GOT1 HSP90AA1 HSP90AB1	6.29e-04	891	81	11	GO:0030424
GeneOntologyCellularComponent	junctional sarcoplasmic reticulum membrane	RYR1 RYR2	6.54e-04	10	81	2	GO:0014701
GeneOntologyCellularComponent	axonal growth cone	DBN1 HSP90AA1 HSP90AB1	7.07e-04	45	81	3	GO:0044295
GeneOntologyCellularComponent	sarcoplasmic reticulum membrane	SLC30A7 RYR1 RYR2	7.07e-04	45	81	3	GO:0033017
GeneOntologyCellularComponent	excitatory synapse	CALB2 SCN8A GRIA3 DBN1	7.98e-04	107	81	4	GO:0060076
GeneOntologyCellularComponent	somatodendritic compartment	CALB2 SCN8A CAPZB PI4K2A GRIA3 RET DBN1 RRM1 TENM2 RPH3A NCS1 HSP90AA1 HSP90AB1	8.36e-04	1228	81	13	GO:0036477
GeneOntologyCellularComponent	dendritic growth cone	HSP90AA1 HSP90AB1	9.54e-04	12	81	2	GO:0044294
GeneOntologyCellularComponent	sarcoplasm	SLC30A7 CALU RYR1 RYR2	1.01e-03	114	81	4	GO:0016528
GeneOntologyCellularComponent	axon terminus	CALB2 GRIA3 CDH1 NCS1 GOT1	1.35e-03	210	81	5	GO:0043679
GeneOntologyCellularComponent	cortical cytoskeleton	CALB2 CAPZB DBN1 CDH1	1.60e-03	129	81	4	GO:0030863
GeneOntologyCellularComponent	neuron projection terminus	CALB2 GRIA3 CDH1 NCS1 GOT1	2.12e-03	233	81	5	GO:0044306
GeneOntologyCellularComponent	sperm head-tail coupling apparatus	SPATA6 CAPZB	2.18e-03	18	81	2	GO:0120212
GeneOntologyCellularComponent	platelet alpha granule lumen	ORM1 ORM2 F8	2.25e-03	67	81	3	GO:0031093
GeneOntologyCellularComponent	dendritic spine	CAPZB GRIA3 DBN1 TENM2 RPH3A	2.50e-03	242	81	5	GO:0043197
GeneOntologyCellularComponent	dendrite terminus	HSP90AA1 HSP90AB1	2.69e-03	20	81	2	GO:0044292
GeneOntologyCellularComponent	node of Ranvier	SCN8A CDH1	2.69e-03	20	81	2	GO:0033268
GeneOntologyCellularComponent	neuron spine	CAPZB GRIA3 DBN1 TENM2 RPH3A	2.73e-03	247	81	5	GO:0044309
GeneOntologyCellularComponent	brush border	CLTRN CAPZB HSP90AA1 HSP90AB1	2.90e-03	152	81	4	GO:0005903
GeneOntologyCellularComponent	cell cortex	CALB2 CAPZB FRYL DBN1 CDH1 RYR1	3.18e-03	371	81	6	GO:0005938
GeneOntologyCellularComponent	sperm plasma membrane	HSP90AA1 HSP90AB1	3.26e-03	22	81	2	GO:0097524
GeneOntologyCellularComponent	extracellular matrix	ORM1 ORM2 PLOD3 ANGPT2 MMP21 ANGPTL5 SVEP1 HSP90AA1	3.87e-03	656	81	8	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ORM1 ORM2 PLOD3 ANGPT2 MMP21 ANGPTL5 SVEP1 HSP90AA1	3.94e-03	658	81	8	GO:0030312
GeneOntologyCellularComponent	brush border membrane	CLTRN HSP90AA1 HSP90AB1	4.12e-03	83	81	3	GO:0031526
GeneOntologyCellularComponent	actin-based cell projection	CALB2 TSPEAR DBN1 CDH1 TENM2	4.52e-03	278	81	5	GO:0098858
GeneOntologyCellularComponent	neuronal cell body	SCN8A CAPZB PI4K2A GRIA3 RET DBN1 RRM1 HSP90AA1 HSP90AB1	4.95e-03	835	81	9	GO:0043025
GeneOntologyCellularComponent	cortical actin cytoskeleton	CALB2 DBN1 CDH1	5.66e-03	93	81	3	GO:0030864
GeneOntologyCellularComponent	platelet alpha granule	ORM1 ORM2 F8	5.66e-03	93	81	3	GO:0031091
Domain	A1A_glycop	ORM1 ORM2	1.81e-05	2	80	2	IPR001500
Domain	Ryanrecept_TM4-6	RYR1 RYR2	5.42e-05	3	80	2	IPR009460
Domain	RyR	RYR1 RYR2	5.42e-05	3	80	2	PF02026
Domain	Ryanodine_rcpt	RYR1 RYR2	5.42e-05	3	80	2	IPR003032
Domain	Cu-oxidase	CP F8	5.42e-05	3	80	2	PF00394
Domain	RR_TM4-6	RYR1 RYR2	5.42e-05	3	80	2	PF06459
Domain	Heat_shock_protein_90_CS	HSP90AA1 HSP90AB1	5.42e-05	3	80	2	IPR019805
Domain	Ryan_recept	RYR1 RYR2	5.42e-05	3	80	2	IPR013333
Domain	Cu-oxidase	CP F8	5.42e-05	3	80	2	IPR001117
Domain	Hsp90_fam	HSP90AA1 HSP90AB1	1.08e-04	4	80	2	IPR001404
Domain	Hsp90_N	HSP90AA1 HSP90AB1	1.08e-04	4	80	2	IPR020575
Domain	Cu-oxidase_2	CP F8	1.08e-04	4	80	2	IPR011706
Domain	HSP90	HSP90AA1 HSP90AB1	1.08e-04	4	80	2	PF00183
Domain	HSP90	HSP90AA1 HSP90AB1	1.08e-04	4	80	2	PS00298
Domain	Cu-oxidase_2	CP F8	1.08e-04	4	80	2	PF07731
Domain	FerI	MYOF FER1L6	1.80e-04	5	80	2	SM01202
Domain	FerB	MYOF FER1L6	1.80e-04	5	80	2	SM01201
Domain	Ferlin_B-domain	MYOF FER1L6	1.80e-04	5	80	2	IPR012561
Domain	Cu_oxidase_CS	CP F8	1.80e-04	5	80	2	IPR033138
Domain	Ferlin_C	MYOF FER1L6	1.80e-04	5	80	2	PF16165
Domain	Ferlin_C	MYOF FER1L6	1.80e-04	5	80	2	IPR032362
Domain	FerIin_dom	MYOF FER1L6	1.80e-04	5	80	2	IPR012968
Domain	FerI	MYOF FER1L6	1.80e-04	5	80	2	PF08151
Domain	FerB	MYOF FER1L6	1.80e-04	5	80	2	PF08150
Domain	Cu-oxidase_3	CP F8	1.80e-04	5	80	2	IPR011707
Domain	MULTICOPPER_OXIDASE1	CP F8	1.80e-04	5	80	2	PS00079
Domain	Cu-oxidase_3	CP F8	1.80e-04	5	80	2	PF07732
Domain	RIH_assoc	RYR1 RYR2	2.69e-04	6	80	2	PF08454
Domain	RIH_assoc-dom	RYR1 RYR2	2.69e-04	6	80	2	IPR013662
Domain	RIH_dom	RYR1 RYR2	2.69e-04	6	80	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	2.69e-04	6	80	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	2.69e-04	6	80	2	IPR015925
Domain	-	RYR1 RYR2	2.69e-04	6	80	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR2	2.69e-04	6	80	2	PF01365
Domain	Ins145_P3_rec	RYR1 RYR2	2.69e-04	6	80	2	PF08709
Domain	Cu_oxidase_Cu_BS	CP F8	2.69e-04	6	80	2	IPR002355
Domain	EF-hand_8	CALU RYR1 RYR2	4.11e-04	34	80	3	PF13833
Domain	MIR	RYR1 RYR2	7.97e-04	10	80	2	PS50919
Domain	MIR	RYR1 RYR2	7.97e-04	10	80	2	PF02815
Domain	MIR	RYR1 RYR2	7.97e-04	10	80	2	SM00472
Domain	MIR_motif	RYR1 RYR2	7.97e-04	10	80	2	IPR016093
Domain	EF-hand-dom_pair	CALB2 CALU SCN8A NCS1 RYR1 RYR2	1.45e-03	287	80	6	IPR011992
Domain	-	CP F8	1.59e-03	14	80	2	2.60.40.420
Domain	LIPOCALIN	ORM1 ORM2	2.36e-03	17	80	2	PS00213
Domain	Lipocalin	ORM1 ORM2	2.65e-03	18	80	2	IPR002345
Domain	HATPase_c	HSP90AA1 HSP90AB1	2.65e-03	18	80	2	SM00387
Domain	HATPase_c	HSP90AA1 HSP90AB1	2.96e-03	19	80	2	PF02518
Domain	Fibrinogen_CS	ANGPT2 ANGPTL5	2.96e-03	19	80	2	IPR020837
Domain	EF_hand_dom	CALB2 CALU NCS1 RYR1 RYR2	3.20e-03	232	80	5	IPR002048
Domain	C2	MYOF WWC2 RPH3A FER1L6	3.24e-03	142	80	4	PS50004
Domain	-	HSP90AA1 HSP90AB1	3.27e-03	20	80	2	3.30.565.10
Domain	HATPase_C	HSP90AA1 HSP90AB1	3.61e-03	21	80	2	IPR003594
Domain	-	MYOF WWC2 RPH3A FER1L6	3.76e-03	148	80	4	2.60.40.150
Domain	Cupredoxin	CP F8	3.96e-03	22	80	2	IPR008972
Domain	EF-hand_1	CALB2 CALU NCS1 RYR2	4.13e-03	152	80	4	PF00036
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	BCLAF1 FAM186A SUPT16H CAPZB C4orf51 LARP1 MMP21 GRIA3 DBN1 CPOX ATP1A4 CDH1 FER1L6 RYR2 HSP90AA1 HSP90AB1	3.70e-07	1442	85	16	35575683
Pubmed	Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.	USP15 HSP90AA1 HSP90AB1	7.82e-07	8	85	3	22451720
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	MRPS18B CALU BCLAF1 SUPT16H CAPZB LARP1 DBN1 SVEP1 GOT1 HSP90AA1 HSP90AB1	1.36e-06	714	85	11	28302793
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	BCLAF1 LARP1 FRYL USP15 HSP90AA1 HSP90AB1	2.41e-06	156	85	6	22952844
Pubmed	Genetic determinants of warfarin dosing in the Han-Chinese population.	ORM1 ORM2 CALU	3.96e-06	13	85	3	19958090
Pubmed	Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.	MYOF PI4K2A USP15	3.96e-06	13	85	3	23146885
Pubmed	Distal promoter regions are responsible for differential regulation of human orosomucoid-1 and -2 gene expression and acute phase responses.	ORM1 ORM2	5.90e-06	2	85	2	24389491
Pubmed	A new strategy for identification of N-glycosylated proteins and unambiguous assignment of their glycosylation sites using HILIC enrichment and partial deglycosylation.	ORM1 ORM2	5.90e-06	2	85	2	15253437
Pubmed	Selective binding of coumarin enantiomers to human alpha1-acid glycoprotein genetic variants.	ORM1 ORM2	5.90e-06	2	85	2	16290938
Pubmed	Retinoids increase alpha-1 acid glycoprotein expression at the transcriptional level through two distinct DR1 retinoic acid responsive elements.	ORM1 ORM2	5.90e-06	2	85	2	15157739
Pubmed	Orosomucoid-1 Arises as a Shared Altered Protein in Two Models of Multiple Sclerosis.	ORM1 ORM2	5.90e-06	2	85	2	37949310
Pubmed	Comparison of alpha-1-acid glycoprotein isoforms from healthy and cancer patients by capillary IEF.	ORM1 ORM2	5.90e-06	2	85	2	17987628
Pubmed	α1-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages.	ORM1 ORM2	5.90e-06	2	85	2	34210751
Pubmed	Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.	ORM1 ORM2	5.90e-06	2	85	2	37640741
Pubmed	An acute phase protein α1-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action.	ORM1 ORM2	5.90e-06	2	85	2	33846468
Pubmed	Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes.	ORM1 ORM2	5.90e-06	2	85	2	28927749
Pubmed	α1-Acid glycoprotein decreases neutrophil migration and increases susceptibility to sepsis in diabetic mice.	ORM1 ORM2	5.90e-06	2	85	2	22415874
Pubmed	Mercury metallation of the copper protein azurin and structural insight into possible heavy metal reactivity.	CP F8	5.90e-06	2	85	2	25265377
Pubmed	Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	22848402
Pubmed	Structure of 1 -acid glycoprotein. The complete amino acid sequence, multiple amino acid substitutions, and homology with the immunoglobulins.	ORM1 ORM2	5.90e-06	2	85	2	4711474
Pubmed	Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.	RYR1 RYR2	5.90e-06	2	85	2	17259277
Pubmed	Structure and expression of the genes coding for human alpha 1-acid glycoprotein.	ORM1 ORM2	5.90e-06	2	85	2	2822385
Pubmed	A mouse tumor-specific transplantation antigen is a heat shock-related protein.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	3458168
Pubmed	Adipocytokine orosomucoid integrates inflammatory and metabolic signals to preserve energy homeostasis by resolving immoderate inflammation.	ORM1 ORM2	5.90e-06	2	85	2	20442402
Pubmed	Mechanism of dimer formation of the 90-kDa heat-shock protein.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	7588731
Pubmed	Orosomucoid1: Involved in vascular endothelial growth factor-induced blood-brain barrier leakage after ischemic stroke in mouse.	ORM1 ORM2	5.90e-06	2	85	2	25264156
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	5.90e-06	2	85	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	5.90e-06	2	85	2	26009179
Pubmed	Molecular characterization and acute phase expression of the multiple Mus caroli alpha 1-acid glycoprotein (AGP) genes. Differences in glucocorticoid stimulation and regulatory elements between the rat and mouse AGP genes.	ORM1 ORM2	5.90e-06	2	85	2	2354997
Pubmed	The Frequency and Clinical Implication of ROS1 and RET Rearrangements in Resected Stage IIIA-N2 Non-Small Cell Lung Cancer Patients.	ROS1 RET	5.90e-06	2	85	2	25905642
Pubmed	Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.	RYR1 RYR2	5.90e-06	2	85	2	32899693
Pubmed	Structural heterogeneity of glycoform of alpha-1 Acid glycoprotein in alcoholic cirrhosis patients.	ORM1 ORM2	5.90e-06	2	85	2	25408356
Pubmed	Nucleotide sequence of the mouse alpha 1-acid glycoprotein gene 1.	ORM1 ORM2	5.90e-06	2	85	2	3676251
Pubmed	Structure and characterisation of a duplicated human alpha 1 acid glycoprotein gene.	ORM1 ORM2	5.90e-06	2	85	2	2970990
Pubmed	E-cadherin and calretinin as immunocytochemical markers to differentiate malignant from benign serous effusions.	CALB2 CDH1	5.90e-06	2	85	2	15285029
Pubmed	The disulfide bonds of alpha1-acid glycoprotein.	ORM1 ORM2	5.90e-06	2	85	2	4603214
Pubmed	HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	33080545
Pubmed	Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosis.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	37011862
Pubmed	Orm2 Deficiency Aggravates High-Fat Diet-Induced Obesity through Gut Microbial Dysbiosis and Intestinal Inflammation.	ORM1 ORM2	5.90e-06	2	85	2	37853937
Pubmed	Proliferation, migration, and resistance to oxidative and thermal stresses of HT1080 cells with knocked out genes encoding Hsp90α and Hsp90β.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	37406487
Pubmed	Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	22194440
Pubmed	Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	18480550
Pubmed	A mouse gene family associated with a major submaxillary-gland glycoprotein.	ORM1 ORM2	5.90e-06	2	85	2	3977853
Pubmed	Structure and expression of mouse alpha 1-acid glycoprotein gene-3 (AGP-3).	ORM1 ORM2	5.90e-06	2	85	2	1605854
Pubmed	Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	22841823
Pubmed	Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.	RYR1 RYR2	5.90e-06	2	85	2	15033925
Pubmed	Substitution of only two residues of human Hsp90alpha causes impeded dimerization of Hsp90beta.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	18347946
Pubmed	Heat shock protein 90 overexpression independently predicts inferior disease-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	19047110
Pubmed	E-Cadherin and Angiopoietin-2 as Potential Biomarkers for Colorectal Cancer With Peritoneal Carcinomatosis.	ANGPT2 CDH1	5.90e-06	2	85	2	34475075
Pubmed	Analysis of the five glycosylation sites of human alpha 1-acid glycoprotein.	ORM1 ORM2	5.90e-06	2	85	2	1567356
Pubmed	Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	12136260
Pubmed	Plasma alpha-1-acid glycoprotein as a potential predictive biomarker for non-haematological adverse events of docetaxel in breast cancer patients.	ORM1 ORM2	5.90e-06	2	85	2	28554261
Pubmed	Expression of hsp90 and cyclin D1 in human breast cancer.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	10376793
Pubmed	Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	33179566
Pubmed	Regulation of embryonic stem cell pluripotency by heat shock protein 90.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	22696450
Pubmed	Evidence for the existence of multiple alpha 1-acid glycoprotein genes in the mouse.	ORM1 ORM2	5.90e-06	2	85	2	3003086
Pubmed	Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	22895790
Pubmed	Interaction of acute-phase-inducible and liver-enriched nuclear factors with the promoter region of the mouse alpha 1-acid glycoprotein gene-1.	ORM1 ORM2	5.90e-06	2	85	2	1371400
Pubmed	Structure of human alpha1-acid glycoprotein and its high-affinity binding site.	ORM1 ORM2	5.90e-06	2	85	2	12480518
Pubmed	Expression of Hsp90 chaperone [corrected] proteins in human tumor tissue.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	19576239
Pubmed	Orosomucoid in liver diseases.	ORM1 ORM2	5.90e-06	2	85	2	34963738
Pubmed	Frequent aerogenous spread with decreased E-cadherin expression of ROS1-rearranged lung cancer predicts poor disease-free survival.	ROS1 CDH1	5.90e-06	2	85	2	26149475
Pubmed	Genetic variations of orosomucoid genes associated with serum alpha-1-acid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer patients.	ORM1 ORM2	5.90e-06	2	85	2	21638284
Pubmed	Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	2925609
Pubmed	Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	2469626
Pubmed	From genotype to phenotype: Are there imaging characteristics associated with lung adenocarcinomas harboring RET and ROS1 rearrangements?	ROS1 RET	5.90e-06	2	85	2	26424208
Pubmed	The bile acid induced hepatokine orosomucoid suppresses adipocyte differentiation.	ORM1 ORM2	5.90e-06	2	85	2	33168190
Pubmed	Mitigation of non-alcoholic steatohepatitis via recombinant Orosomucoid 2, an acute phase protein modulating the Erk1/2-PPARγ-Cd36 pathway.	ORM1 ORM2	5.90e-06	2	85	2	37355990
Pubmed	Molecular cloning of cDNAs corresponding to two genes of alpha 1-acid glycoprotein and characterization of two alleles of AGP-1 in the mouse.	ORM1 ORM2	5.90e-06	2	85	2	2475311
Pubmed	Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.	RYR1 RYR2	5.90e-06	2	85	2	30542613
Pubmed	Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	36270993
Pubmed	Hsp90 regulation of fibroblast activation in pulmonary fibrosis.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	28239659
Pubmed	A synthetic retinoic acid receptor agonist Am80 ameliorates renal fibrosis via inducing the production of alpha-1-acid glycoprotein.	ORM1 ORM2	5.90e-06	2	85	2	32651445
Pubmed	Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.	RYR1 RYR2	5.90e-06	2	85	2	15280431
Pubmed	Expression of the ryanodine receptor isoforms in immune cells.	RYR1 RYR2	5.90e-06	2	85	2	11673493
Pubmed	B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.	RYR1 RYR2	5.90e-06	2	85	2	11673462
Pubmed	Isoform differentiation of intact AGP from human serum by capillary electrophoresis-mass spectrometry.	ORM1 ORM2	5.90e-06	2	85	2	20617306
Pubmed	Despite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	37028636
Pubmed	CXCR2 and RET single nucleotide polymorphisms in pancreatic cancer.	RET CXCR2	5.90e-06	2	85	2	19057948
Pubmed	alpha 1-Acid glycoprotein binds human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein via N-linked glycans.	ORM1 ORM2	5.90e-06	2	85	2	7795416
Pubmed	Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.	RYR1 RYR2	5.90e-06	2	85	2	25370123
Pubmed	Investigation of genetic variants of alpha-1 acid glycoprotein by ultra-performance liquid chromatography-mass spectrometry.	ORM1 ORM2	5.90e-06	2	85	2	19018521
Pubmed	Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.	RYR1 RYR2	5.90e-06	2	85	2	18618700
Pubmed	Conserved conformational changes in the ATPase cycle of human Hsp90.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	18400751
Pubmed	Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor.	HSP90AA1 HSP90AB1	5.90e-06	2	85	2	22019372
Pubmed	LHPP impedes energy metabolism by inducing ubiquitin-mediated degradation of PKM2 in glioblastoma.	CALU HSP90AA1 HSP90AB1	7.71e-06	16	85	3	33948363
Pubmed	Association of warfarin dose with genes involved in its action and metabolism.	ORM1 ORM2 CALU	7.71e-06	16	85	3	17048007
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SLC30A7 MYOF PLOD3 MRPS18B CALU BCLAF1 SUPT16H CAPZB GLIPR2 LARP1 OS9 OAT RRM1 HSP90AA1	9.90e-06	1440	85	14	30833792
Pubmed	Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.	BCLAF1 SUPT16H OAT HSP90AA1 HSP90AB1	1.00e-05	116	85	5	37117180
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MYOF PLOD3 MRPS18B BCLAF1 SUPT16H CAPZB LARP1 CRYBG1 OAT DBN1 CDH1 HSP90AA1 HSP90AB1	1.11e-05	1257	85	13	36526897
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	PHKA1 MYOF PLOD3 JADE3 CLK2 BCLAF1 NKAPD1 SUPT16H OAT RET NCS1	1.36e-05	910	85	11	36736316
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR2	1.77e-05	3	85	2	18403125
Pubmed	ALK, ROS1 and RET rearrangements in lung squamous cell carcinoma are very rare.	ROS1 RET	1.77e-05	3	85	2	26973202
Pubmed	ALK, ROS1 and RET fusions in 1139 lung adenocarcinomas: a comprehensive study of common and fusion pattern-specific clinicopathologic, histologic and cytologic features.	ROS1 RET	1.77e-05	3	85	2	24629636
Pubmed	Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.	HSP90AA1 HSP90AB1	1.77e-05	3	85	2	20226818
Pubmed	Effect of mannosylated derivatives on HIV-1 infection of macrophages and lymphocytes.	ORM1 ORM2	1.77e-05	3	85	2	9455924
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR2	1.77e-05	3	85	2	7876312
Pubmed	Modulation of Akt kinase activity by binding to Hsp90.	HSP90AA1 HSP90AB1	1.77e-05	3	85	2	10995457
Pubmed	Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.	RYR1 RYR2	1.77e-05	3	85	2	24123915
Pubmed	Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.	HSP90AA1 HSP90AB1	1.77e-05	3	85	2	18550790
Interaction	STK33 interactions	PHKA1 CALU USP15 HSP90AA1 HSP90AB1	4.73e-07	38	83	5	int:STK33
Interaction	APOA1 interactions	ORM1 CP RET USP15 IGKV2-40 GOT1 HSP90AA1	1.49e-05	193	83	7	int:APOA1
GeneFamily	Ferlin family	MYOF FER1L4 FER1L6	4.73e-07	6	53	3	828
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	2.52e-05	3	53	2	287
GeneFamily	Heat shock 90kDa proteins	HSP90AA1 HSP90AB1	8.38e-05	5	53	2	586
GeneFamily	Lipocalins	ORM1 ORM2	1.40e-03	19	53	2	631
GeneFamily	Fibrinogen C domain containing	ANGPT2 ANGPTL5	2.42e-03	25	53	2	554
GeneFamily	EF-hand domain containing	CALB2 CALU NCS1 RYR2	3.86e-03	219	53	4	863
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	ROS1 RET	6.12e-03	40	53	2	321
GeneFamily	X-linked mental retardation\|Angiotensin receptors	GRIA3 ZNF81	1.06e-02	53	53	2	103
Coexpression	LEE_LIVER_CANCER_MYC_E2F1_DN	ORM1 ORM2 OAT CPOX GOT1	1.86e-06	64	83	5	M5636
Coexpression	LEE_LIVER_CANCER_ACOX1_DN	ORM1 ORM2 OAT CPOX GOT1	2.01e-06	65	83	5	M14811
Coexpression	GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN	PHKA1 MYOF CALU CPOX RRM1 HSP90AB1	4.12e-05	199	83	6	M5382
Coexpression	GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN	PLOD3 INPP5B GLIPR2 CPOX CXCR2 IDNK	4.24e-05	200	83	6	M5101
Coexpression	GSE13306_TREG_RA_VS_TCONV_RA_UP	ORM2 C4orf51 OAT IDE TENM2 HSP90AA1	4.24e-05	200	83	6	M3226
Coexpression	LEE_LIVER_CANCER_E2F1_DN	ORM1 ORM2 OAT GOT1	5.14e-05	64	83	4	M15346
Coexpression	LEE_LIVER_CANCER_MYC_TGFA_DN	ORM1 ORM2 OAT GOT1	5.46e-05	65	83	4	M17372
Coexpression	EPPERT_PROGENITOR	CALU SUPT16H IDE RRM1 HSP90AA1	7.86e-05	138	83	5	M19232
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#3_top-relative-expression-ranked_1000	MYOF FER1L4 CRYBG1 CP CDH1 SLC2A12 SEMA3E	2.73e-05	218	85	7	gudmap_developingLowerUrinaryTract_P1_ureter_1000_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#2_top-relative-expression-ranked_500	MYOF FER1L4 CRYBG1 CP SEMA3E	4.19e-05	96	85	5	gudmap_developingLowerUrinaryTract_P1_ureter_500_k2
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	MGAT4C TENM2 RPH3A CDH12 RYR1 RYR2	6.15e-07	159	85	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-5\|TCGA-Kidney / Sample_Type by Project: Shred V9	GRIA3 RET SVEP1 IFNAR2	1.30e-05	75	85	4	c1ab2eb49eebfdb10dc32c935804e8771260ca6c
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	MGAT4C RPH3A CDH12 RYR1 RYR2	1.52e-05	163	85	5	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	Endothelial-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	ANGPT2 L3MBTL1 RFTN2 DBN1 MGAT4C	1.62e-05	165	85	5	10087d8bd2985906ef19547fe77eb178ae5e1638
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ORM1 MYOF GLIPR2 SEMA3E CXCR2	1.62e-05	165	85	5	ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CPB1 RPH3A CDH12 RYR1 FER1L6	1.92e-05	171	85	5	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANGPT2 TSPEAR DBN1 MGAT4C F8	2.26e-05	177	85	5	dfaed388926ce050730492a532824af68bf4feff
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOF WWC2 HS3ST5 CDH1 SEMA3E	2.52e-05	181	85	5	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SGSM1 ANGPT2 CP RFTN2 F8	2.59e-05	182	85	5	2cc434e46985c66fc36de05344a67aa96d90abc9
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TMEM176A GRIA3 CP OAT SVEP1	2.59e-05	182	85	5	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SGSM1 ANGPT2 CP RFTN2 F8	2.59e-05	182	85	5	0cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SGSM1 ANGPT2 CP RFTN2 F8	2.59e-05	182	85	5	3e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	WWC2 DUOXA1 HS3ST5 CDH1 SEMA3E	2.66e-05	183	85	5	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	WWC2 DUOXA1 HS3ST5 CDH1 SEMA3E	2.66e-05	183	85	5	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	OAT CPB1 CPOX USP15 HSP90AA1	2.80e-05	185	85	5	e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	DUOXA1 HS3ST5 CP ROS1 CDH1	2.80e-05	185	85	5	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOF WWC2 HS3ST5 CDH1 SEMA3E	2.87e-05	186	85	5	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	PND03\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ORM1 WWC2 HSP90AA1 SEMA3E CXCR2	2.95e-05	187	85	5	b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALU GLIPR2 CP RET SVEP1	3.34e-05	192	85	5	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALU GLIPR2 CP RET SVEP1	3.34e-05	192	85	5	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM176A GLIPR2 CP DBN1 SVEP1	3.34e-05	192	85	5	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	critical-Epithelial-Secretory\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MYOF CP OAT CDH1 FER1L6	3.69e-05	196	85	5	7da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCell	Control-Classical_Monocyte-cMono_2\|Classical_Monocyte / Disease condition and Cell class	BCLAF1 YPEL5 USP15 HSP90AA1 HSP90AB1	3.78e-05	197	85	5	eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HS3ST5 CPB1 MGAT4C RYR2 SEMA3E	3.78e-05	197	85	5	3a0e97bfebe82f9687d518baaad7f20d0ffea8a1
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ORM1 ORM2 DUOXA1 CLTRN ROS1	3.78e-05	197	85	5	d2a4d7e92e91bcc47a7657da2e5c8a3ad7eb08ad
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYOF WWC2 CP CDH1 SEMA3E	3.87e-05	198	85	5	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MYOF CP OAT CDH1 FER1L6	3.87e-05	198	85	5	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYOF WWC2 CP CDH1 SEMA3E	3.96e-05	199	85	5	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	metastatic_Brain\|World / Location, Cell class and cell subclass	CALU TMEM176A CP CDH1 METTL27	3.96e-05	199	85	5	a6793145de96bcdbfd4fe04159e34ea2244ca5a8
ToppCell	background\|World / Sample and Cell Type and Tumor Cluster (all cells)	ORM1 ORM2 TMEM176A CP GOT1	3.96e-05	199	85	5	5a6d0e00bfe1351eea192b54020bedeef78854e9
ToppCell	background-Hepatocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	ORM1 ORM2 TMEM176A CP GOT1	4.06e-05	200	85	5	423cca10df6ae0489a8fe7e7df87e70364dac022
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYOF ANGPT2 ATP1A4 TENM2 RYR2	4.06e-05	200	85	5	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	background-Hepatocytes\|background / Sample and Cell Type and Tumor Cluster (all cells)	ORM1 ORM2 TMEM176A CP GOT1	4.06e-05	200	85	5	787d35b5c2f2ad967ae14e99496a0299ac7e72fd
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYOF WWC2 CP CDH1 SEMA3E	4.06e-05	200	85	5	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	MYOF ANGPT2 ATP1A4 TENM2 RYR2	4.06e-05	200	85	5	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	BCLAF1 YPEL5 USP15 HSP90AA1 HSP90AB1	4.06e-05	200	85	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CLTRN C4orf51 MGAT4C CDH12	6.53e-05	113	85	4	feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCell	COVID-19-kidney-Epithelial_Doublet\|kidney / Disease (COVID-19 only), tissue and cell type	MGAT4C CDH12 RYR1 RYR2	9.36e-05	124	85	4	d6f59ddb9b9df02b5201f23fa5fb78f3fd891ee9
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	JADE3 RET MGAT4C RYR1	1.26e-04	134	85	4	2647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-MEP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PHKA1 FAM186A GRIA3 CPB1	1.38e-04	137	85	4	0bb5cccc31e7c44d44a2db3f59b68f9a81503151
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	L3MBTL1 GRIA3 RYR1 ZBBX	1.62e-04	143	85	4	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CALB2 TSPEAR CP RET	1.67e-04	144	85	4	0322fef818a963be00535d5f141f028d43de5c6a
ToppCell	Children_(3_yrs)-Immune-mast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CALB2 CPB1 RET ATP1A4	1.76e-04	146	85	4	f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCell	facs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 ROS1 CDH1 PLD4	1.80e-04	147	85	4	9d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCell	facs-Marrow-B-cells-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 ROS1 CDH1 PLD4	1.80e-04	147	85	4	38552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Cerebellum / BrainAtlas - Mouse McCarroll V32	L3MBTL1 FAM227A RET CDH1	1.90e-04	149	85	4	6e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MGAT4C RPH3A CDH12 RYR1	1.95e-04	150	85	4	0205318a870e091add66ee4305747dda9f51510d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ORM1 GLIPR2 METTL27 NCS1	2.00e-04	151	85	4	7b50425d2bbd7b6ff2a6e67d3e2470a4455740e0
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Papillary_Adenocarcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	ORM1 ORM2 MRPS18B CLTRN	2.21e-04	155	85	4	57259549d7ad97d9f628b821417be5ddac7dbff7
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CALB2 TMEM176A CP RET	2.26e-04	156	85	4	896e2d958be0a5c62fb6eebad2dfb7e1ce69f3ad
ToppCell	severe_COVID-19-pDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	RET CDH1 RYR1 PLD4	2.43e-04	159	85	4	ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYOF CP CDH1 FER1L6	2.55e-04	161	85	4	9cfbbcd38ec2e75376bbc26001964b6991ad0e21
ToppCell	NS-moderate-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CALB2 RET DBN1 ATP1A4	2.74e-04	164	85	4	35c673380f75cb4bfe080089bc723c4373bcc7a5
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLTRN CP CDH1 FER1L6	2.80e-04	165	85	4	6fdce8b23736409a23884ef3918638ffc067a86f
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLTRN CP CDH1 FER1L6	2.80e-04	165	85	4	dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLTRN CP CDH1 FER1L6	2.80e-04	165	85	4	baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JADE3 CDH1 SLC2A12 SEMA3E	2.87e-04	166	85	4	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOF TMEM176A CP PLD4	2.87e-04	166	85	4	b3d9b61847c6c96b8cb28b8a6aeda52f43c706ab
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JADE3 CDH1 SLC2A12 SEMA3E	2.87e-04	166	85	4	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	Endothelial-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ANGPT2 RFTN2 MGAT4C CDH12	2.87e-04	166	85	4	c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYOF ROS1 ANGPTL5 SEMA3E	2.93e-04	167	85	4	a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-6\|TCGA-Colorectal / Sample_Type by Project: Shred V9	CPB1 TEX11 ANGPTL5 SEMA3E	3.00e-04	168	85	4	5ce3129a023a48a3d7e6b9306c1fc5addfef9675
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLTRN SCN8A GOT1 PLD4	3.00e-04	168	85	4	84977db9d71e59208727885320cc18d80d064380
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYOF GRIA3 CP SVEP1	3.07e-04	169	85	4	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYOF ROS1 SLC2A12 ANGPTL5	3.07e-04	169	85	4	2abdd8ae9a5d88aac30992142d1b502c959bc015
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYOF ROS1 ANGPTL5 SEMA3E	3.07e-04	169	85	4	0c341f91dc21aaf92bead18d59684d11510502ce
ToppCell	Lymphoid-Lymphoid-T_cells_(Cd8+_T_cell)\|Lymphoid / shred on cell class and cell subclass (v4)	PI4K2A TMEM176A DBN1 SVEP1	3.14e-04	170	85	4	20fd1a312c81c1bf3c5d2d6caf9b578e6b7a4171
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ROS1 ANGPTL5 CDH12 SEMA3E	3.14e-04	170	85	4	84d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOF TMEM176A CP PLD4	3.14e-04	170	85	4	067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCell	Ciliated_cells-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	TSPEAR FAM227A FER1L6 ZBBX	3.14e-04	170	85	4	8b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLTRN PI4K2A GLIPR2 SVEP1	3.21e-04	171	85	4	2a34685f7d83d1cf9a88d304173cbca868c5f9fd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYOF ROS1 ANGPTL5 SEMA3E	3.28e-04	172	85	4	cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SGSM1 DUOXA1 NCS1 RYR1	3.28e-04	172	85	4	9befd44bce43eb5dc1fe3d2e44608f442cf74a47
ToppCell	droplet-Lung-nan-21m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B OS9 CDH1 CXCR2	3.28e-04	172	85	4	1b133be191252e7053faeacf9547730c3ae28d21
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PHKA1 SGSM1 IDE SLC2A12	3.28e-04	172	85	4	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	YPEL5 USP15 METTL27 CXCR2	3.28e-04	172	85	4	4790323a072cfe76127d704665a42c09601d84be
ToppCell	droplet-Lung-nan-21m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B OS9 CDH1 CXCR2	3.28e-04	172	85	4	b3c53fd7e50f36de6a8585ae21d04e17932f262c
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B OS9 CDH1 CXCR2	3.35e-04	173	85	4	53e97835d7a518c278e7b90a0734eb0095d6aa33
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INPP5B OS9 CDH1 CXCR2	3.35e-04	173	85	4	117163c5cd2b7aaa1c0682c8ac44b4249df4d2f8
ToppCell	FLU-Healthy-5\|Healthy / Virus stimulation, Condition and Cluster	GPR137 ZFP28 CDH1 METTL27	3.35e-04	173	85	4	8c218ec1ba927e9312f3df5f312395e907ab64ab
ToppCell	droplet-Lung-LUNG-1m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B OS9 CDH1 CXCR2	3.35e-04	173	85	4	889a880de5fc19d26b82cfef3067869a28ef17ca
ToppCell	FLU-Healthy-5\|FLU / Virus stimulation, Condition and Cluster	GPR137 ZFP28 CDH1 METTL27	3.35e-04	173	85	4	bd4f06d971f9d138749094047c9337dfbaf5da31
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INPP5B OS9 CDH1 CXCR2	3.35e-04	173	85	4	01df9baeedf30e3a4891738554cdd300394dbb96
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYOF HS3ST5 ANGPTL5 SEMA3E	3.43e-04	174	85	4	912a9e892b29d945666fc37c986009c97c668ac8
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	WWC2 HS3ST5 CDH1 SEMA3E	3.43e-04	174	85	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B HYLS1 CDH1 CXCR2	3.50e-04	175	85	4	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	AT1-AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	WWC2 TSPEAR CDH1 SEMA3E	3.50e-04	175	85	4	bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B HYLS1 CDH1 CXCR2	3.50e-04	175	85	4	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	facs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGSM1 DUOXA1 CP F8	3.58e-04	176	85	4	057d2759fdc67176c25802b57a78064d8cc93205
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGSM1 DUOXA1 CP F8	3.58e-04	176	85	4	b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCell	ASK452-Epithelial-Secretory\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	MYOF L3MBTL1 CLTRN CP	3.58e-04	176	85	4	dd334c8a8a31dc26b2d558df0ef6bed6dc1a6610
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANGPT2 RET DBN1 F8	3.58e-04	176	85	4	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANGPT2 TSPEAR RET F8	3.66e-04	177	85	4	d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CALB2 HS3ST5 ROS1 ANGPTL5	3.66e-04	177	85	4	62f180d5a487b449f715de49ee1e1e11c4e0cf4d
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANGPT2 GLIPR2 CP SVEP1	3.66e-04	177	85	4	599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANGPT2 TSPEAR MGAT4C F8	3.74e-04	178	85	4	ad3de3e03a401dac64431a541899445262246347
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	C4orf51 TENM2 RYR1 SEMA3E	3.82e-04	179	85	4	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOF HS3ST5 CDH1 SEMA3E	3.82e-04	179	85	4	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANGPT2 TSPEAR RET F8	3.82e-04	179	85	4	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	JADE3 GRIA3 ATP1A4 SVEP1	3.90e-04	180	85	4	32d871738a24071b70084a7e80148a516110c78b
Drug	lidocaine	PHKA1 ORM1 ORM2 ROS1 RET RYR1 RYR2	1.97e-06	160	83	7	CID000003676
Drug	Clozic	ORM1 ORM2 CP	7.55e-06	11	83	3	CID000071697
Drug	cobalt-60	SLC30A7 GRIA3 CP CPB1 IDE MGAT4C RYR1 RYR2 PLD4	1.24e-05	390	83	9	CID000061492
Drug	9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine	HSP90AA1 HSP90AB1	1.31e-05	2	83	2	DB02754
Drug	Geldanamycin	HSP90AA1 HSP90AB1	1.31e-05	2	83	2	DB02424
Drug	norlorcainide	ORM1 ORM2	1.31e-05	2	83	2	CID000162188
Drug	8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE	HSP90AA1 HSP90AB1	1.31e-05	2	83	2	DB07877
Drug	4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL	HSP90AA1 HSP90AB1	1.31e-05	2	83	2	DB07594
Drug	carocainide	ORM1 ORM2	1.31e-05	2	83	2	CID000071970
Drug	2,4,4-trimethyl-2-pentanol	ORM1 ORM2	1.31e-05	2	83	2	CID000094740
Drug	3-phenylindole	ORM1 ORM2	1.31e-05	2	83	2	CID000096502
Drug	AC1L3M3Y	ORM1 ORM2 ROS1 MGAT4C	1.65e-05	42	83	4	CID000091455
Drug	cis-diammineplatinum(II	RYR1 RYR2	3.93e-05	3	83	2	CID000159790
Drug	didesmethylimipramine	ORM1 ORM2	3.93e-05	3	83	2	CID000159642
Drug	2-hydroxyheptanoic acid	RYR1 RYR2	3.93e-05	3	83	2	CID002750949
Drug	8N3-cADPR	RYR1 RYR2	3.93e-05	3	83	2	CID000127713
Drug	aminodantrolene	RYR1 RYR2	3.93e-05	3	83	2	CID009570289
Drug	4-hydroxytertatolol	ORM1 ORM2	3.93e-05	3	83	2	CID000163871
Drug	d2786	BCLAF1 CP	3.93e-05	3	83	2	CID000137467
Drug	2-hydroxycarbazole	RYR1 RYR2	3.93e-05	3	83	2	CID000093551
Drug	MD 770222	ORM1 ORM2	3.93e-05	3	83	2	CID000129805
Drug	p-hydroxyketorolac	ORM1 ORM2	3.93e-05	3	83	2	CID003082630
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR1 RYR2	3.93e-05	3	83	2	CID005748312
Drug	1-decyl-3-(N,N-diethylcarbamoyl)piperidine	ORM1 ORM2	3.93e-05	3	83	2	CID000120652
Drug	ibuprofenyl-CoA	ORM1 ORM2	3.93e-05	3	83	2	CID003081818
Drug	glycerol	ORM1 ORM2 DUOXA1 CLK2 SUPT16H CP CPOX RRM1 MGAT4C RPH3A PLD4 HSP90AB1	4.52e-05	829	83	12	CID000000753
Drug	galactosylhydroxylysine	ORM1 ORM2 PLOD3	5.09e-05	20	83	3	CID000123986
Drug	ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A	WWC2 CALU FRYL RET RRM1 CDH1	6.52e-05	188	83	6	1630_DN
Drug	PCB74	RYR1 RYR2	7.84e-05	4	83	2	CID000036218
Drug	indoloquinolizidine	ORM1 ORM2	7.84e-05	4	83	2	CID000098358
Drug	AC1L1HWB	ORM1 ORM2	7.84e-05	4	83	2	CID000004318
Drug	N-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide	HSP90AA1 HSP90AB1	7.84e-05	4	83	2	ctd:C576667
Drug	6-deoxy-6-fluoro-galactose	ORM1 ORM2	7.84e-05	4	83	2	CID000165242
Drug	148504-47-6	RYR1 RYR2	7.84e-05	4	83	2	CID006444275
Drug	SC 38249	RYR1 RYR2	7.84e-05	4	83	2	CID000134834
Drug	AC1L1U7A	RYR1 RYR2	7.84e-05	4	83	2	CID000035682
Drug	Ceforanide [60925-61-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A	GPR137 MYOF L3MBTL1 SVEP1 RYR1 RYR2	7.98e-05	195	83	6	3309_UP
Drug	Gly-His-Lys acetate salt; Up 200; 1uM; PC3; HT_HG-U133A	MYOF CALU DBN1 RRM1 F8 HSP90AB1	8.21e-05	196	83	6	6570_UP
Drug	AC1MMZLG	ORM1 ORM2 CDH1 F8	1.06e-04	67	83	4	CID003269220
Drug	Caffeine	SLC30A7 ORM1 ORM2 CALU OAT CDH1 RYR1 RYR2 HSP90AA1	1.08e-04	515	83	9	ctd:D002110
Drug	lerisetron	ORM1 ORM2	1.30e-04	5	83	2	CID000065997
Drug	1uyd	F8 HSP90AA1	1.30e-04	5	83	2	CID000448970
Drug	14-F	ORM1 ORM2	1.30e-04	5	83	2	CID000079736
Drug	A 68930	RYR1 RYR2	1.30e-04	5	83	2	ctd:C065380
Drug	moxaprindine	ORM1 ORM2	1.30e-04	5	83	2	CID000068699
Drug	AC1NV8X5	ORM1 ORM2	1.30e-04	5	83	2	CID005473883
Drug	dimethylaluminum chloride	PLOD3 CP	1.30e-04	5	83	2	CID000079147
Drug	alpha-ManMNT	ORM1 ORM2	1.30e-04	5	83	2	CID006438897
Drug	romazarit	ORM1 ORM2	1.30e-04	5	83	2	CID000071321
Drug	mercury	ORM1 ORM2 OS9 CPB1 CPOX GOT1 RYR1 RYR2 HSP90AA1	1.58e-04	542	83	9	CID000023931
Drug	LOPAC	RYR1 RYR2 CXCR2	1.77e-04	30	83	3	CID000062696
Drug	Dansyl ethylenediamine	ORM1 ORM2	1.95e-04	6	83	2	CID000161851
Drug	1 h vs	ORM1 ORM2	1.95e-04	6	83	2	CID000064999
Drug	chloro-m-cresol	RYR1 RYR2	1.95e-04	6	83	2	CID000012008
Drug	AC1MZP2J	ORM1 ORM2	1.95e-04	6	83	2	CID003950037
Drug	fulvene	BCLAF1 CP	1.95e-04	6	83	2	CID000136323
Drug	MBED	RYR1 RYR2	1.95e-04	6	83	2	CID000129958
Drug	AC1O528X	RYR1 RYR2	1.95e-04	6	83	2	CID006475857
Drug	NSC114784	RYR1 RYR2	1.95e-04	6	83	2	CID000419425
Drug	pentacarboxyporphyrin	CP CPOX	1.95e-04	6	83	2	CID000168756
Drug	palytoxin	ORM1 ORM2 ANGPT2	2.36e-04	33	83	3	ctd:C010272
Drug	retinyl phosphate	RET MGAT4C	2.72e-04	7	83	2	CID006438395
Drug	bornaprolol	ORM1 ORM2	2.72e-04	7	83	2	CID000068863
Drug	artocarpin lectin	MGAT4C CXCR2	2.72e-04	7	83	2	CID005358260
Drug	[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate	RYR1 RYR2	2.72e-04	7	83	2	CID009547999
Drug	nipecotamide	ORM1 ORM2	2.72e-04	7	83	2	CID000092980
Drug	Azumoleno	RYR1 RYR2	2.72e-04	7	83	2	CID000056259
Drug	norperazine	ORM1 ORM2	2.72e-04	7	83	2	CID000151090
Drug	Br2BAPTA	RYR1 RYR2	2.72e-04	7	83	2	CID003081001
Drug	NSC330499	HSP90AA1 HSP90AB1	2.72e-04	7	83	2	CID000433447
Drug	cetoleic acid	CP GOT1	2.72e-04	7	83	2	CID005282771
Drug	N-acryloxysuccinimide	ORM1 ORM2	2.72e-04	7	83	2	CID000181508
Drug	PK 8165	ORM1 ORM2	2.72e-04	7	83	2	CID000071219
Drug	7-anilinocoumarin-4-acetic acid	ORM1 ORM2	2.72e-04	7	83	2	CID000133902
Drug	europium	WWC2 PLOD3 RYR1 RYR2	2.90e-04	87	83	4	CID000023981
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	MYOF FER1L4 FER1L6	7.45e-07	7	83	3	DOID:11724 (implicated_via_orthology)
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	2.34e-05	3	83	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	2.34e-05	3	83	2	DOID:8545 (implicated_via_orthology)
Disease	serine protease inhibitor Kazal-type 2 measurement	ORM1 ORM2	1.16e-04	6	83	2	EFO_0802054
Disease	coagulation factor XA measurement	ORM1 ORM2	4.23e-04	11	83	2	EFO_0020266
Disease	coagulation factor X measurement	ORM1 ORM2	5.98e-04	13	83	2	EFO_0020265
Disease	melanoma	HS3ST5 CRYBG1 CP ROS1 RET	6.86e-04	248	83	5	C0025202
Disease	rheumatoid arthritis, COVID-19	INPP5B FRYL IFNAR2	7.90e-04	64	83	3	EFO_0000685, MONDO_0100096
Disease	Tremor, Rubral	SCN8A CP	9.14e-04	16	83	2	C0750940
Disease	Ataxia, Appendicular	SCN8A CP	9.14e-04	16	83	2	C0750937
Disease	Ataxia, Motor	SCN8A CP	9.14e-04	16	83	2	C0278161
Disease	Abnormal coordination	SCN8A CP	9.14e-04	16	83	2	C0520966
Disease	Ataxia, Truncal	SCN8A CP	9.14e-04	16	83	2	C0427190
Disease	Ataxia, Sensory	SCN8A CP	9.14e-04	16	83	2	C0240991
Disease	Disease Exacerbation	MRPS18B CRYBG1 RRM1 CDH1	1.23e-03	165	83	4	C0235874
Disease	Cannabis use, age at onset	LARP1 RYR2	1.30e-03	19	83	2	EFO_0004847, EFO_0007585
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	HSP90AA1 HSP90AB1	1.30e-03	19	83	2	DOID:4928 (is_marker_for)
Disease	pulmonary hypertension (biomarker_via_orthology)	ANGPT2 RYR1 RYR2	1.51e-03	80	83	3	DOID:6432 (biomarker_via_orthology)
Disease	Ataxia	SCN8A CP	2.25e-03	25	83	2	C0004134
Disease	alcohol use disorder (implicated_via_orthology)	ANGPT2 ATP1A4 RYR1 RYR2	2.26e-03	195	83	4	DOID:1574 (implicated_via_orthology)
Disease	asthma exacerbation measurement	CPOX TENM2 CDH12	2.32e-03	93	83	3	EFO_0007614

Protein segments in the cluster

Peptide	Gene	Start	Entry
SYDSWDYSELDPERF	FAM227A	291	F5H4B4
QKYFYRGRLDWDENT	CLK2	411	P49760
GKWFYIASAFRNEEY	ORM2	41	P19652
KDWEGNEAYSLYEHF	ANGPT2	376	O15123
DSYYSQSIEAADDWF	C1orf185	141	Q5T7R7
WEEYKNATYGYVLDD	CALU	126	O43852
DDTLAYASYDNFWLE	ANGPTL5	251	Q86XS5
YASYDNFWLEDETRF	ANGPTL5	256	Q86XS5
RDGDSYRSPWSNKYD	CAPZB	66	P47756
DADWLELTTFYYKQG	RFTN2	281	Q52LD8
SLKDEYQYSFWDLFR	SLC2A12	256	Q8TD20
NESWYLDDNIKTYSD	CP	926	P00450
RQWKYKDDDDDQLFY	PLOD3	181	O60568
EASKAYSSVDEYFWG	MGAT4C	356	Q9UBM8
DGLFYYEQDLWAEKF	LARP1	681	Q6PKG0
YGEFYKSLTNDWEDH	HSP90AB1	301	P08238
DSDDGNTYLDWYLQK	IGKV2D-40	51	P01614
LRWAFKLYDLDNDGY	NCS1	101	P62166
SRLDTFDYDWYNVSD	GPR137	246	Q96N19
SYDQKDAWVRDNVYS	PHKA1	36	P46020
EELDWGSKYYASLQE	FER1L4	1106	A9Z1Z3
SGSRKAGYWNEYERF	GRIA3	391	P42263
FDNDENYGKGIEWYR	HS3ST5	126	Q8IZT8
GYKEEEFSWSQYLRS	L3MBTL1	376	Q9Y468
YWRYDSDKDQALTED	MMP21	416	Q8N119
FEDFWKGEDLSNYSY	CXCR2	11	P25025
WYRRQNGTEDESYEY	FRYL	81	O94915
WIKNTEYTSGYERED	HACE1	796	Q8IYU2
GVSYWKASEGAEYDD	F8	121	P00451
AADWALYTYEDGSDD	DBN1	26	Q16643
KKVWDYNYDDESDSD	IFNAR2	311	P48551
FYDRWAPDYDQDVAT	METTL27	31	Q8N6F8
GYKDADYWLRRFEAE	PI4K2A	266	Q9BTU6
KAAYIGTSNWSEDYF	PLD4	436	Q96BZ4
DRVARYFEYKRDWDS	HYLS1	211	Q96M11
SELGWKFYDADDYHP	IDNK	26	Q5T6J7
SYDQTGKEVADRWYS	GLIPR2	71	Q9H4G4
YFLHDDRDDGVDYWA	BCLAF1	846	Q9NYF8
AGFKDIRSYRYWDAE	GOT1	151	P17174
GKWFYIASAFRNEEY	ORM1	41	P02763
TYKYDTGSDDWDTSE	INPP5B	581	P32019
DLYFYDATRNRWFEG	KLHDC4	331	Q8TBB5
DSDDGNTYLDWYLQK	IGKV2-40	51	A0A087WW87
WRKYDTDRSGYIEAN	CALB2	116	P22676
ADQDYDYLTDWGPRF	CDH12	761	P55289
EGKTDRTEEWYGTQY	IDE	486	P14735
NEEYGEFYKSLTNDW	HSP90AA1	306	P07900
QYILDKGFYTSFEDW	CRYBG1	1376	Q9Y4K1
FYQEDETDEYQSWKR	FAM186A	446	A6NE01
TWRLGENYAEEYAKA	DUOXA1	131	Q1HG43
DFYWYYSGKDVIEEQ	RYR1	3931	P21817
SDFYWYYSGKDVIDE	RYR2	3886	Q92736
YRYFEVEEADGNKQW	CPOX	261	P36551
GSDDWAYDQGIRYSF	CPB1	361	P15086
SEDSEADRYSDYGWG	C4orf51	181	C9J302
NPDSYYLFADTWKEE	JADE3	61	Q92613
SESDKDQDYDYLNEW	CDH1	851	P12830
DQDYDYLNEWGNRFK	CDH1	856	P12830
QYEIEGYNAWRDTSK	FER1L6	1461	Q2WGJ9
DISVWDYDIGKSNDY	RPH3A	636	Q9Y2J0
AALKLWNEDFRYGYS	TMEM176A	131	Q96HP8
TKSDETGWTTFYDYD	TENM2	1691	Q9NT68
RLYSNWRKGEDEYAN	SUPT16H	16	Q9Y5B9
WGAANRLDYSYDDFL	SVEP1	871	Q4LDE5
WDVEGRKYFDFLSSY	OAT	71	P04181
GYYQSAFDWDDETAK	OS9	146	Q13438
WEDKYLNDLEDSYGQ	ATP1A4	896	Q13733
GDKAYAWDTNEEYLF	CLTRN	36	Q9HBJ8
SDGFDEESQRYYWRP	NKAPD1	61	Q6ZUT1
WKYLESEEYQERYGS	MRPS18B	56	Q9Y676
YNKSGRWFYLDDSEE	ZFP28	376	Q8NHY6
GWIYEFATEDSQRYK	YPEL5	81	P62699
WEEARDYDGKVFYID	WWC2	16	Q6AWC2
EVWGEEFEKLYASYE	RRM1	361	P23921
DGKWYYFDDSSVSTA	USP15	901	Q9Y4E8
SYLENGTKGFDWEEY	SCN8A	291	Q9UQD0
LATNYLDWDDTKYYD	TEX11	271	Q8IYF3
DWYNNSLYYSDTKGD	ROS1	711	P08922
VGDLDYEKSVYWDYA	SGSM1	301	Q2NKQ1
FSRDAYWEKLYVDQA	RET	31	P07949
VISKWRDNDAFSYGY	SLC30A7	86	Q8NEW0
ELFAGLYSDYWSRDA	SEMA3E	186	O15041
EDAQFWFDASRKGLY	TSPEAR	281	Q8WU66
DDGEYWSNRAASYKG	SPATA6	441	Q9NWH7
EKEDRESSEYYWKSG	ZBBX	56	A8MT70
LNTEWDYEYKDFGKF	ZNF81	161	P51508
SYDINRAVDEKGWEY	MYOF	981	Q9NZM1