Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	extrinsic component of external side of plasma membrane	ARSA CUBN	1.14e-04	4	92	2	GO:0031232
Domain	NumbF	NUMBL NUMB	2.35e-05	2	91	2	PF06311
Domain	Numb_domain	NUMBL NUMB	2.35e-05	2	91	2	IPR010449
Domain	Numb/numb-like	NUMBL NUMB	2.35e-05	2	91	2	IPR016698
Domain	zf-RING_2	RNF6 RLIM PHRF1 RNF128	1.19e-04	52	91	4	PF13639
Domain	PID	APPL2 NUMBL NUMB	3.36e-04	28	91	3	PF00640
Domain	Tyr_Pase_AS	PTPN11 PTPRC PTPRS DUSP8	4.44e-04	73	91	4	IPR016130
Domain	PID	APPL2 NUMBL NUMB	5.01e-04	32	91	3	PS01179
Domain	PTPc	PTPN11 PTPRC PTPRS	7.11e-04	36	91	3	SM00194
Domain	TYR_PHOSPHATASE_1	PTPN11 PTPRC PTPRS DUSP8	8.26e-04	86	91	4	PS00383
Domain	TYR_PHOSPHATASE_dom	PTPN11 PTPRC PTPRS DUSP8	8.62e-04	87	91	4	IPR000387
Domain	TYR_PHOSPHATASE_2	PTPN11 PTPRC PTPRS DUSP8	8.62e-04	87	91	4	PS50056
Domain	TYR_PHOSPHATASE_PTP	PTPN11 PTPRC PTPRS	9.01e-04	39	91	3	PS50055
Domain	PTB	APPL2 NUMBL NUMB	9.70e-04	40	91	3	SM00462
Domain	Beta-tubulin_BS	TUBB6 TUBB8	1.03e-03	10	91	2	IPR013838
Domain	Beta_tubulin	TUBB6 TUBB8	1.03e-03	10	91	2	IPR002453
Domain	PTB/PI_dom	APPL2 NUMBL NUMB	1.04e-03	41	91	3	IPR006020
Domain	PTPase_domain	PTPN11 PTPRC PTPRS	1.04e-03	41	91	3	IPR000242
Domain	Y_phosphatase	PTPN11 PTPRC PTPRS	1.04e-03	41	91	3	PF00102
Domain	-	PTPN11 PTPRC PTPRS DUSP8	1.06e-03	92	91	4	3.90.190.10
Domain	Znf_RING	RNF6 RLIM PHRF1 MARCHF7 CCNB1IP1 RNF128 SH3RF3	1.07e-03	326	91	7	IPR001841
Domain	TUBULIN_B_AUTOREG	TUBB6 TUBB8	1.25e-03	11	91	2	PS00228
Domain	Prot-tyrosine_phosphatase-like	PTPN11 PTPRC PTPRS DUSP8	1.39e-03	99	91	4	IPR029021
Domain	Znf_C3HC4_RING-type	RNF6 RLIM PHRF1 MARCHF7 RNF128	1.53e-03	172	91	5	IPR018957
Domain	-	RNF6 KDM4C RLIM PHRF1 MARCHF7 WDFY3 RNF128 SH3RF3	1.56e-03	449	91	8	3.30.40.10
Domain	Znf_RING/FYVE/PHD	RNF6 KDM4C RLIM PHRF1 MARCHF7 WDFY3 RNF128 SH3RF3	1.79e-03	459	91	8	IPR013083
Domain	EGF_2	EPHB4 FBN2 TENM1 ADAM11 CUBN SSPOP	1.88e-03	265	91	6	PS01186
Domain	Sulfatase_CS	ARSA ARSG	2.70e-03	16	91	2	IPR024607
Domain	PTPc_motif	PTPN11 PTPRC PTPRS	2.99e-03	59	91	3	SM00404
Domain	Tyr_Pase_cat	PTPN11 PTPRC PTPRS	2.99e-03	59	91	3	IPR003595
Domain	ZF_RING_1	RNF6 RLIM PHRF1 CCNB1IP1 RNF128 SH3RF3	2.99e-03	291	91	6	PS00518
Domain	SULFATASE_1	ARSA ARSG	3.04e-03	17	91	2	PS00523
Domain	SULFATASE_2	ARSA ARSG	3.04e-03	17	91	2	PS00149
Domain	ZF_RING_2	RNF6 RLIM PHRF1 CCNB1IP1 RNF128 SH3RF3	3.36e-03	298	91	6	PS50089
Domain	Sulfatase	ARSA ARSG	3.41e-03	18	91	2	PF00884
Domain	Lig_chan-Glu_bd	GRIK5 GRIN2B	3.41e-03	18	91	2	PF10613
Domain	Glu/Gly-bd	GRIK5 GRIN2B	3.41e-03	18	91	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIK5 GRIN2B	3.41e-03	18	91	2	SM00918
Domain	Iontro_rcpt	GRIK5 GRIN2B	3.41e-03	18	91	2	IPR001320
Domain	Iono_rcpt_met	GRIK5 GRIN2B	3.41e-03	18	91	2	IPR001508
Domain	Lig_chan	GRIK5 GRIN2B	3.41e-03	18	91	2	PF00060
Domain	Sulfatase_N	ARSA ARSG	3.41e-03	18	91	2	IPR000917
Domain	PBPe	GRIK5 GRIN2B	3.41e-03	18	91	2	SM00079
Domain	USP_CS	CYLD USP42 USP15	4.10e-03	66	91	3	IPR018200
Domain	-	TUBB6 TUBB8	4.21e-03	20	91	2	3.30.1330.20
Domain	-	TUBB6 TUBB8	4.64e-03	21	91	2	1.10.287.600
Domain	zf-C3HC4	RNF6 RLIM PHRF1 MARCHF7 RNF128	4.70e-03	223	91	5	PF00097
Domain	USP_1	CYLD USP42 USP15	4.84e-03	70	91	3	PS00972
Domain	UCH	CYLD USP42 USP15	5.04e-03	71	91	3	PF00443
Domain	USP_2	CYLD USP42 USP15	5.04e-03	71	91	3	PS00973
Domain	Tubulin_C	TUBB6 TUBB8	5.09e-03	22	91	2	PF03953
Domain	Tubulin/FtsZ_2-layer-sand-dom	TUBB6 TUBB8	5.09e-03	22	91	2	IPR018316
Domain	-	TUBB6 TUBB8	5.09e-03	22	91	2	3.40.50.1440
Domain	Tubulin_C	TUBB6 TUBB8	5.09e-03	22	91	2	SM00865
Domain	USP_3	CYLD USP42 USP15	5.24e-03	72	91	3	PS50235
Domain	USP_dom	CYLD USP42 USP15	5.24e-03	72	91	3	IPR028889
Domain	Peptidase_C19_UCH	CYLD USP42 USP15	5.24e-03	72	91	3	IPR001394
Domain	Tub_FtsZ_C	TUBB6 TUBB8	5.56e-03	23	91	2	IPR008280
Domain	Tubulin_C	TUBB6 TUBB8	5.56e-03	23	91	2	IPR023123
Domain	TUBULIN	TUBB6 TUBB8	5.56e-03	23	91	2	PS00227
Domain	Tubulin	TUBB6 TUBB8	5.56e-03	23	91	2	IPR000217
Domain	Tubulin	TUBB6 TUBB8	5.56e-03	23	91	2	SM00864
Pathway	REACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS	TUBB6 TUBB8 LRRC7 GRIN2B	6.16e-05	44	69	4	M27934
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	TUBB6 DNAH10 HAP1 TUBB8	6.73e-05	45	69	4	M47670
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	WDR74 PTPN11 SMG7 USP42 RLIM MMS19 PFKP USP15 FOXK1 FBXO34 VCP MADD	4.55e-07	689	96	12	36543142
Pubmed	Numblike and Numb differentially affect p53 and Sonic Hedgehog signaling.	NUMBL NUMB	7.54e-06	2	96	2	21893032
Pubmed	Analysis of multigene families by DNA fingerprinting of conserved domains: directed cloning of tissue-specific protein tyrosine phosphatases.	PTPN11 PTPRS	7.54e-06	2	96	2	8479755
Pubmed	EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation.	NUMBL NUMB	7.54e-06	2	96	2	31433979
Pubmed	Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway.	NUMBL NUMB	7.54e-06	2	96	2	34124033
Pubmed	Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis.	NUMBL NUMB	7.54e-06	2	96	2	27383182
Pubmed	Numb and Numblike regulate sarcomere assembly and maintenance.	NUMBL NUMB	7.54e-06	2	96	2	35104799
Pubmed	Brain-derived neurotrophic factor enhances association of protein tyrosine phosphatase PTP1D with the NMDA receptor subunit NR2B in the cortical postsynaptic density.	PTPN11 GRIN2B	7.54e-06	2	96	2	10381539
Pubmed	Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike.	NUMBL NUMB	7.54e-06	2	96	2	17513721
Pubmed	VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.	VPS13D VCP	7.54e-06	2	96	2	34133214
Pubmed	Regulation of vascular endothelial growth factor receptor function in angiogenesis by numb and numb-like.	NUMBL NUMB	7.54e-06	2	96	2	26069237
Pubmed	LAR-RPTPs Directly Interact with Neurexins to Coordinate Bidirectional Assembly of Molecular Machineries.	PTPRC PTPRS	7.54e-06	2	96	2	33037075
Pubmed	circKDM4C suppresses tumor progression and attenuates doxorubicin resistance by regulating miR-548p/PBLD axis in breast cancer.	KDM4C PBLD	7.54e-06	2	96	2	31406252
Pubmed	Numb deficiency causes impaired trafficking of mGlu5 in neurons and autistic-like behaviors.	NUMBL NUMB	7.54e-06	2	96	2	31129078
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	DLGAP4 KNDC1 LRRC7 GRIN2B SH3RF3 VCP	1.86e-05	197	96	6	36604605
Pubmed	[Polymorphic Variants of Glutamate Receptor (GRIK5, GRIN2B) and Serotonin Receptor (HTR2A) Genes Are Associated with Chronic Obstructive Pulmonary Disease].	GRIK5 GRIN2B	2.26e-05	3	96	2	28900078
Pubmed	Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.	NUMBL NUMB	2.26e-05	3	96	2	10551880
Pubmed	Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor cilia.	NUMBL NUMB	2.26e-05	3	96	2	25319694
Pubmed	Protein tyrosine phosphatase-σ regulates hematopoietic stem cell-repopulating capacity.	PTPRC PTPRS	2.26e-05	3	96	2	25415437
Pubmed	The Notch regulator Numb links the Notch and TCR signaling pathways.	NUMBL NUMB	2.26e-05	3	96	2	15634911
Pubmed	Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis.	NUMBL NUMB	2.26e-05	3	96	2	21571219
Pubmed	The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.	RNF6 RLIM	2.26e-05	3	96	2	16204183
Pubmed	Protein-tyrosine phosphatase expression in pre-B cell NALM-6.	PTPN11 PTPRS	2.26e-05	3	96	2	1370651
Pubmed	The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1.	NUMBL NUMB	2.26e-05	3	96	2	24336247
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	TUBB6 SIAE VPS13D APPL2 TUBB8 AOX1 PKHD1 PBLD CUBN ABHD14B UTRN VCP	2.38e-05	1016	96	12	19056867
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CYLD VPS13D AKAP8 NUMBL NUMB PFKP UTRN SH3RF3 NARS2 FOXK1 MADD	2.61e-05	861	96	11	36931259
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	CYLD WDR74 TTF2 SMG7 NUMBL TUBB8 KNDC1 NUMB MARCHF7 FOXK1 TBC1D17 MADD	2.93e-05	1038	96	12	26673895
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TUBB6 PTPN11 VIPAS39 PTPRC SMG7 NUMBL PTPRS DUSP8 NUMB CPD UTRN MADD	3.24e-05	1049	96	12	27880917
Pubmed	G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy.	CSF3 UTRN	4.51e-05	4	96	2	25865621
Pubmed	Dynamic changes in the expression of protein tyrosine phosphatases during preimplantation mouse development: semi-quantification by real-time PCR.	PTPN11 PTPRS	4.51e-05	4	96	2	14967925
Pubmed	Numb-deficient satellite cells have regeneration and proliferation defects.	NUMBL NUMB	4.51e-05	4	96	2	24170859
Pubmed	Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions.	RNF6 RLIM	4.51e-05	4	96	2	12874135
Pubmed	Numb is required to prevent p53-dependent senescence following skeletal muscle injury.	NUMBL NUMB	4.51e-05	4	96	2	26503169
Pubmed	Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis.	NUMBL NUMB	4.51e-05	4	96	2	8755477
Pubmed	Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche.	NUMBL NUMB	4.51e-05	4	96	2	17174898
Pubmed	Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis.	NUMBL NUMB	4.51e-05	4	96	2	9169836
Pubmed	Nonsense-mediated decay factor SMG7 sensitizes cells to TNFα-induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1.	CYLD SMG7	4.51e-05	4	96	2	32602581
Pubmed	The Lnx family proteins function as molecular scaffolds for Numb family proteins.	NUMBL NUMB	4.51e-05	4	96	2	11922143
Pubmed	A severe form of Noonan syndrome and autosomal dominant café-au-lait spots - evidence for different genetic origins.	PTPN11 SPRED2	4.51e-05	4	96	2	19120036
Pubmed	Chromosomal localization of the Huntingtin associated protein (HAP-1) gene in mouse and humans with radiation hybrid and interspecific backcross mapping.	CSF3 HAP1	4.51e-05	4	96	2	10087300
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	TUBB6 SIAE FBN2 PTPRC PTPRS CPD PFKP FBXO34 B4GALT3	5.14e-05	613	96	9	22268729
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CYLD FBH1 SPRED2 APPL2 KDM4C ANKRD36 GRIN2B WDFY3 UTRN MGAT5B VCP MADD B4GALT3	5.28e-05	1285	96	13	35914814
Pubmed	A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.	TUBB6 METTL1 TUBB8 FOXK1 VCP	5.30e-05	145	96	5	23349634
Pubmed	Novel Isoform DTX3c Associates with UBE2N-UBA1 and Cdc48/p97 as Part of the EphB4 Degradation Complex Regulated by the Autocrine IGF-II/IRA Signal in Malignant Mesothelioma.	EPHB4 VCP	7.50e-05	5	96	2	37108544
Pubmed	USP15 antagonizes CRL4CRBN-mediated ubiquitylation of glutamine synthetase and neosubstrates.	USP15 VCP	7.50e-05	5	96	2	34583995
Pubmed	M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.	PTPN11 CSF3	7.50e-05	5	96	2	19587381
Pubmed	PIWIL1 destabilizes microtubule by suppressing phosphorylation at Ser16 and RLIM-mediated degradation of Stathmin1.	PIWIL1 RLIM	7.50e-05	5	96	2	26317901
Pubmed	The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.	NUMBL NUMB	7.50e-05	5	96	2	12011466
Pubmed	Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function.	RLIM USP15 VCP	8.66e-05	31	96	3	36114200
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	SMG7 TENM1 NUMB LRRC7 CPD UTRN	9.27e-05	263	96	6	34702444
Pubmed	Genetic regulation of glutamate receptor ion channels.	GRIK5 GRIN2B	1.12e-04	6	96	2	10331083
Pubmed	Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2.	LRRC7 GRIN2B	1.12e-04	6	96	2	16120608
Pubmed	Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models.	NUMBL NUMB	1.12e-04	6	96	2	36260685
Pubmed	GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A.	USP15 VCP	1.12e-04	6	96	2	36065190
Pubmed	SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling.	NUMBL NUMB	1.12e-04	6	96	2	37843276
Pubmed	A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution.	NUMBL NUMB	1.12e-04	6	96	2	7568168
Pubmed	The IA-2 interactome.	PTPRS MADD	1.12e-04	6	96	2	16273344
Pubmed	Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis.	PTPRC CSF3	1.12e-04	6	96	2	24990886
Pubmed	β1-integrin is a cell-autonomous factor mediating the Numb pathway for cardiac progenitor maintenance.	NUMBL NUMB	1.12e-04	6	96	2	29653101
Pubmed	Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance.	NUMBL NUMB	1.12e-04	6	96	2	31054872
Pubmed	Progenitor cell maintenance requires numb and numblike during mouse neurogenesis.	NUMBL NUMB	1.12e-04	6	96	2	12410312
Pubmed	Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.	PTPRC PTPRS	1.57e-04	7	96	2	1454056
Pubmed	Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.	PTPRC PTPRS	1.57e-04	7	96	2	12376545
Pubmed	Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.	CYLD VCP	1.57e-04	7	96	2	24461064
Pubmed	The enigma of the numb-Notch relationship during mammalian embryogenesis.	NUMBL NUMB	1.57e-04	7	96	2	16508312
Pubmed	NUMBL Interacts with TAK1, TRAF6 and NEMO to Negatively Regulate NF-κB Signaling During Osteoclastogenesis.	NUMBL NUMB	1.57e-04	7	96	2	28974699
Pubmed	Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling.	NUMBL NUMB	1.57e-04	7	96	2	25535389
Pubmed	Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors.	NUMBL NUMB	1.57e-04	7	96	2	24843018
Pubmed	Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization.	NUMBL NUMB	1.57e-04	7	96	2	15598981
Pubmed	The carboxyterminus of the ATP-binding cassette transporter A1 interacts with a beta2-syntrophin/utrophin complex.	AOX1 UTRN	1.57e-04	7	96	2	12054535
Pubmed	Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice.	GRIN2B WDFY3	1.57e-04	7	96	2	36897941
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	EPHB4 TUBB6 SIAE ARSA PTPRS TUBB8 PBLD PGLYRP2 CUBN ABHD14B VCP	1.80e-04	1070	96	11	23533145
Pubmed	Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5.	HOXB4 PTPRC	2.09e-04	8	96	2	18952892
Pubmed	Exosomal MicroRNA Transport from Salivary Mesenchyme Regulates Epithelial Progenitor Expansion during Organogenesis.	NUMBL NUMB	2.09e-04	8	96	2	28041903
Pubmed	EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children.	COL6A5 LRRC7	2.09e-04	8	96	2	24348519
Pubmed	Numb regulates somatic cell lineage commitment during early gonadogenesis in mice.	NUMBL NUMB	2.09e-04	8	96	2	28360133
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SMG7 NUMBL PTPRS NFIX KNDC1 NUMB TMPRSS5 LRRC7 CPD USP15 SSPOP UTRN SH3RF3	2.28e-04	1489	96	13	28611215
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CYLD TUBB6 FBN2 AKAP8 SMG7 AOX1 PHRF1 MMS19 WDFY3 FOXK1 VCP	2.59e-04	1116	96	11	31753913
Pubmed	A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.	LRRC7 GRIN2B	2.68e-04	9	96	2	28130356
Pubmed	Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.	GRIK5 GRIN2B	2.68e-04	9	96	2	34100982
Pubmed	Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.	NUMBL NUMB	2.68e-04	9	96	2	9303539
Pubmed	EphB6-null mutation results in compromised T cell function.	EPHB4 PTPRC	2.68e-04	9	96	2	15599401
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CYLD TUBB6 AKAP8 NUMBL PTPRS DLGAP4 LRRC7 GRIK5 GRIN2B WDFY3	3.32e-04	963	96	10	28671696
Pubmed	The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis.	NUMBL NUMB	3.34e-04	10	96	2	34571841
Pubmed	FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection.	PTPN11 PTPRC	3.34e-04	10	96	2	17213291
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	PTPN11 HMX3 MMS19 HS6ST3 VCP	4.63e-04	231	96	5	36597993
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CYLD USP42 HMX3 MMS19 PFKP USP15 UTRN FOXK1 VCP TAF1D	4.64e-04	1005	96	10	19615732
Pubmed	Genomic analysis of mouse retinal development.	VIPAS39 APPL2 METRN PTPRS DUSP8 PHRF1 MMS19 WDFY3 FOXK1 ARSG	4.68e-04	1006	96	10	15226823
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB4 SIAE ARL6IP6 FBN2 ARSA PTPRS CPD USP15 VCP MADD B4GALT3	4.80e-04	1201	96	11	35696571
Pubmed	RBM24 is a major regulator of muscle-specific alternative splicing.	NUMBL NUMB	4.89e-04	12	96	2	25313962
Pubmed	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.	PTPRC PTPRS	4.89e-04	12	96	2	9624153
Pubmed	Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase.	RLIM MARCHF7	4.89e-04	12	96	2	34611473
Pubmed	Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.	PTPRS KNDC1 PFKP	5.63e-04	58	96	3	31067491
Pubmed	Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains.	CYLD USP15	5.77e-04	13	96	2	19373254
Pubmed	HIV-1 rev depolymerizes microtubules to form stable bilayered rings.	TUBB6 TUBB8	5.77e-04	13	96	2	10908577
Pubmed	Expression patterns of sulfatase genes in the developing mouse embryo.	ARSA ARSG	5.77e-04	13	96	2	20503373
Pubmed	Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits.	PTPRC PBLD	5.77e-04	13	96	2	28402856
Pubmed	Derepression of a neuronal inhibitor due to miRNA dysregulation in a schizophrenia-related microdeletion.	NPTX2 GRIN2B	5.77e-04	13	96	2	23332760
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	APPL2 NUMBL PTPRS DLGAP4 KNDC1 LSAMP LRRC7 GRIN2B PFKP UTRN VCP MADD	5.78e-04	1431	96	12	37142655
Pubmed	HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.	TUBB6 TUBB8	6.71e-04	14	96	2	12486001
Cytoband	Ensembl 112 genes in cytogenetic band chr10p15	FBH1 TUBB8 PFKP	9.12e-04	90	96	3	chr10p15
GeneFamily	Ring finger proteins	RNF6 RLIM PHRF1 MARCHF7 RNF128 SH3RF3	4.57e-04	275	65	6	58
GeneFamily	Ubiquitin specific peptidases	CYLD USP42 USP15	1.07e-03	56	65	3	366
GeneFamily	Sulfatases	ARSA ARSG	1.88e-03	18	65	2	410
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRC PTPRS	2.56e-03	21	65	2	813
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 DNAH10 TENM1 PKHD1 GRIN2B SSPOP	2.95e-06	184	96	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 DNAH10 TENM1 PKHD1 GRIN2B SSPOP	2.95e-06	184	96	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 DNAH10 TENM1 PKHD1 GRIN2B SSPOP	2.95e-06	184	96	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	BL-critical-LOC-Myeloid-Neutrophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PTPRC NUMB CPD WDFY3 PPP1R15A AQP9	4.24e-06	196	96	6	f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CYLD PTPRC KDM4C TENM1 ANKRD36 UTRN	4.36e-06	197	96	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	moderate-Myeloid-Neutrophil\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PTPRC NUMB CPD PPP1R15A USP15 AQP9	4.49e-06	198	96	6	a6306dac34af5783f3a734ef1eaa7a0c03267b4f
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	SIAE DNAH10 KNDC1 C7orf57 MGAT5B	1.57e-05	145	96	5	ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 DNAH10 PKHD1 COL6A5 GRIN2B	2.52e-05	160	96	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 DNAH10 PKHD1 COL6A5 GRIN2B	2.52e-05	160	96	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNAH10 TENM1 PKHD1 LRRC7 GRIN2B	2.67e-05	162	96	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	ASK428-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	TENM1 MFSD2B C7orf57 PNMA3 HDC	3.18e-05	168	96	5	c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTF2 ARSA SMG7 HAP1 GRIK5	3.18e-05	168	96	5	de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CSF3 RNF6 TTC31 ABHD14B SSPOP	3.27e-05	169	96	5	c6e5b179461996ced6c7621dc01cec00d401f4e8
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRS PGLYRP2 PFKP AQP9 HDC	4.41e-05	180	96	5	41e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UTS2 DNAH10 KDM4C ARSG HDC	4.53e-05	181	96	5	338c7362d258a87f1a6b1a65376f5394d4b2b4b2
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AOX1 TENM1 PKHD1 PBLD CUBN	4.53e-05	181	96	5	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRN PIWIL1 TENM1 TMPRSS5 ADAM11	4.65e-05	182	96	5	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRN PIWIL1 TENM1 TMPRSS5 ADAM11	4.65e-05	182	96	5	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRN PIWIL1 TENM1 TMPRSS5 ADAM11	4.65e-05	182	96	5	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	wk_15-18-Epithelial-PNS-Early_Schwann\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NPTX2 TUBB8 HMX3 TMPRSS5 MGAT5B	4.77e-05	183	96	5	7e8366ec8117d36cec67f77dcb0e9a6032d87fcb
ToppCell	cellseq2-Immune-Hematopoietic-Granulocytic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PTPRC NUMB USP15 AQP9 HDC	4.77e-05	183	96	5	cfbf8539104cef9ca830ad4f6bb278746f7078f7
ToppCell	cellseq2-Immune-Hematopoietic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PTPRC NUMB USP15 AQP9 HDC	4.77e-05	183	96	5	324ec4374b552da7ce03809945b3a0798342d4ba
ToppCell	(04)_Pre-ciliated-(3)_72hpi\|(04)_Pre-ciliated / shred by cell type and Timepoint	VPS13D METRN DNAH10 KNDC1 HDC	5.43e-05	188	96	5	f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RABEPK HOXB4 NPTX2 METRN TMPRSS5	5.70e-05	190	96	5	5a82709eeb68df4563bb42b97636d110126d2f97
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FBN2 PTPRC NUMB USP15 AQP9	5.85e-05	191	96	5	47a2afc4102199b4bc76bd01b2967c8016186462
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RABEPK HOXB4 NPTX2 METRN HMX3	5.99e-05	192	96	5	56f2388c9c4e19883ae5cff332c77f596ff744a8
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FBN2 AOX1 CPD WDFY3 AQP9	6.45e-05	195	96	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FBN2 AOX1 CPD WDFY3 AQP9	6.45e-05	195	96	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	BL-critical-LOC-Myeloid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NUMB CPD WDFY3 PPP1R15A AQP9	6.77e-05	197	96	5	932a7fae4979b561688e6222505df0f4e510ab11
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	UTS2 KDM4C SYNGR2 PPP1R15A HDC	6.77e-05	197	96	5	61f909737c5f630beffdd326c6844215643dbdde
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PTPRC NUMB PPP1R15A USP15 AQP9	6.77e-05	197	96	5	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	CYLD PPP1R15A USP15 UTRN TAF1D	6.77e-05	197	96	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYLD PPP1R15A USP15 UTRN TAF1D	6.93e-05	198	96	5	44417089b62056269cac38d3134ff209c05b7007
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RABEPK HOXB4 NPTX2 METRN TMPRSS5	6.93e-05	198	96	5	c506334d81af672ef9ddc8c4fd2a790bdb58e63e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYLD PPP1R15A USP15 UTRN TAF1D	6.93e-05	198	96	5	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NUMB WDFY3 PPP1R15A AQP9 MIR22HG	6.93e-05	198	96	5	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	UTS2 KDM4C SYNGR2 PPP1R15A HDC	6.93e-05	198	96	5	a1247a5efd92f95c6227c0e71dc8a0427eb54b7f
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NUMB CPD WDFY3 PPP1R15A AQP9	7.10e-05	199	96	5	119807ea333d1dc7743c6b9f03a2c63e09e19541
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NUMB CPD WDFY3 PPP1R15A AQP9	7.10e-05	199	96	5	691e04871cd6cac0ea5fca1b7fd6421df9315db6
Drug	Spironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A	CYLD VPS13D FBN2 RNF6 KDM4C NFIX WDFY3 TBC1D17	1.73e-06	199	94	8	5781_DN
Drug	aa 288	NUMBL NUMB	1.69e-05	2	94	2	CID002724650
Drug	AC1NDSSF	FBN2 PFKP	1.69e-05	2	94	2	CID004631017
Drug	Triamterene [396-01-0]; Down 200; 15.8uM; PC3; HT_HG-U133A	EPHB4 CYLD FBN2 SMG7 NFIX CPD WDFY3	1.83e-05	198	94	7	7307_DN
Drug	Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A	VPS13D PTPN11 SMG7 KDM4C AOX1 CPD GRIK5	1.83e-05	198	94	7	6525_DN
Disease	idiopathic scoliosis (implicated_via_orthology)	PTPN11 DNAH10 SSPOP	1.54e-05	16	91	3	DOID:0060250 (implicated_via_orthology)
Disease	bombesin receptor-activated protein C6orf89 measurement	PGLYRP2 CUBN	9.35e-05	5	91	2	EFO_0801428
Disease	reaction time measurement	PTPN11 LINC01559 AKAP8 SMG7 DNAH10 NFIX PKHD1 MFSD2B GRIN2B	1.99e-04	658	91	9	EFO_0008393
Disease	Noonan syndrome (is_implicated_in)	PTPN11 SPRED2	2.60e-04	8	91	2	DOID:3490 (is_implicated_in)
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP42 PIWIL1 VCP	3.91e-04	46	91	3	DOID:5426 (implicated_via_orthology)
Disease	facial paralysis (implicated_via_orthology)	TUBB6 TUBB8	4.17e-04	10	91	2	DOID:13934 (implicated_via_orthology)
Disease	complex cortical dysplasia with other brain malformations 7 (implicated_via_orthology)	TUBB6 TUBB8	4.17e-04	10	91	2	DOID:0090132 (implicated_via_orthology)
Disease	ptosis (implicated_via_orthology)	TUBB6 TUBB8	4.17e-04	10	91	2	DOID:0060260 (implicated_via_orthology)
Disease	tubulinopathy (implicated_via_orthology)	TUBB6 TUBB8	4.17e-04	10	91	2	DOID:0112227 (implicated_via_orthology)
Disease	cerebellar ataxia, mental retardation and dysequlibrium syndrome (implicated_via_orthology)	TUBB6 TUBB8	6.08e-04	12	91	2	DOID:0050997 (implicated_via_orthology)
Disease	5-methyluridine (ribothymidine) measurement	PTPRS C7orf57	8.36e-04	14	91	2	EFO_0020013
Disease	melanoma	WDR74 CSF3 KDM4C PCDHB8 CUBN	1.04e-03	248	91	5	C0025202
Disease	leukemia (implicated_via_orthology)	HOXB4 PTPN11	1.55e-03	19	91	2	DOID:1240 (implicated_via_orthology)
Disease	response to alcohol	PTPN11 DUSP8 PKHD1	1.63e-03	75	91	3	EFO_0005526
Disease	temporal lobe epilepsy (is_marker_for)	GRIK5 GRIN2B	1.72e-03	20	91	2	DOID:3328 (is_marker_for)
Disease	activities of daily living score measurement	PIWIL1 GRIK5	1.90e-03	21	91	2	EFO_0008451
Disease	disease of metabolism (implicated_via_orthology)	PTPN11 PFKP	1.90e-03	21	91	2	DOID:0014667 (implicated_via_orthology)
Disease	lymphocyte count, response to vaccine	LINC01559 PIWIL1	2.09e-03	22	91	2	EFO_0004587, EFO_0004645
Disease	body weight loss	TBX15 PKHD1	2.09e-03	22	91	2	EFO_0005245
Disease	alcoholic liver disease	FBN2 AOX1 LSAMP	2.11e-03	82	91	3	EFO_0008573
Disease	Huntington's disease (is_implicated_in)	HAP1 GRIN2B	2.28e-03	23	91	2	DOID:12858 (is_implicated_in)
Disease	alcohol use disorder measurement, alcohol dependence	PKHD1 TMPRSS5	2.48e-03	24	91	2	EFO_0009458, MONDO_0007079
Disease	response to radiation	PTPRC NUMBL KDM4C	2.58e-03	88	91	3	GO_0009314
Disease	physical activity	DLGAP4 PKHD1 LRRC7	2.58e-03	88	91	3	EFO_0003940
Disease	brain cancer (implicated_via_orthology)	NUMBL NUMB	2.91e-03	26	91	2	DOID:1319 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	PTPN11 GRIN2B WDFY3	3.01e-03	93	91	3	C1535926

Protein segments in the cluster

Peptide	Gene	Start	Entry
VFAIFDSRNLGAPRG	AQP9	176	O43315
FRSLSALFGRDQGPT	B4GALT3	31	O60512
GEGIQDRESSFRFQP	AKAP8	116	O43823
SLGLNFGDAARQTPR	DUSP8	471	Q13202
NSPAIVRFSGQSRGV	FBXO34	231	Q9NWN3
AFNFSTCPGSGERRI	ADAM11	671	O75078
FAQIGPARSGFRLET	MIR22HG	21	Q0VDD5
AQASLPQGRRFDGVD	ARSG	376	Q96EG1
GANPNITDFFGRTAL	ANKRD36	121	A6QL64
PTEAFAREARFPGQN	DLGAP4	36	Q9Y2H0
RTNLPSNTAFRGFGF	AOX1	911	Q06278
VRQGSFRGFPALSQK	NUMBL	301	Q9Y6R0
FIADAFTARAFRGNP	PBLD	6	P30039
FIVGGANPNRSFSDV	RABEPK	51	Q7Z6M1
SQEGSPVFAGFEGRR	MSL3P1	331	P0C860
FREALPGSGQARFSV	ABHD14B	21	Q96IU4
NGGSSRVRIFSRFPE	HDC	606	P19113
SANRFVSIGPRDGNF	NFIX	476	Q14938
VAFQAGSFLASRPRQ	MADD	521	Q8WXG6
QVRARSEAGYGPFGQ	EPHB4	506	P54760
VRPFAGAQVFAERAG	METRN	86	Q9UJH8
AQFASQGARAGFLRR	LRRC7	1101	Q96NW7
FQPFQDGSSGQRRLI	MMS19	701	Q96T76
AGFALSQVGDLAFPR	HMX3	81	A6NHT5
PRNTRFAINFFTSIG	CWC22	621	Q9HCG8
LGGQFSARRLGDSPF	MGAT5B	41	Q3V5L5
FQDAVRLRGRSFAGN	PFKP	376	Q01813
DPGFRSNFRRQNGAA	PGLYRP2	311	Q96PD5
NFEESLLRGRFAPSG	FAM214B	351	Q7L5A3
VQARNLSNGSVPGFR	PHRF1	611	Q9P1Y6
LERLAQGFFPSSSQG	KDM4C	221	Q9H3R0
PVAGFFINRSQRTGS	MFSD2B	96	A6NFX1
PQFSGQSFAERSGRG	ARSA	231	P15289
SNPGDFTLSVRRNGA	PTPN11	36	Q06124
QGRLDFPGFVQTSLA	MRGPRE	86	Q86SM8
ENGSLPRFVPRFNFS	HS6ST3	116	Q8IZP7
RELFSNLQEFAGPSG	METTL7A	56	Q9H8H3
AFRLAARSPQGLGAF	PTPRS	591	Q13332
GQRRESSFQPEAGFG	HOXB4	41	P17483
SSFQPEAGFGRRAAC	HOXB4	46	P17483
FQSGPSRQNRGFRAQ	CUBN	1601	O60494
SRGQGSQRCIPEFFL	FBH1	51	Q8NFZ0
QANGSYASRRGPFDF	C7orf57	136	Q8NEG2
FSESYGSRRAQGVPQ	COL6A5	326	A8TX70
RFVFQGPFGSRATGR	HAP1	106	P54257
SRGRDLNRSFPDQFS	CPD	211	O75976
NGVFVDGAFQRRGAP	FOXK1	166	P85037
FLDQNRGSRRTNPFG	APPL2	461	Q8NEU8
VPDNRASEASQGFRF	MARCHF7	336	Q9H992
PAFASAFQRRAGGVL	CSF3	171	P09919
SRGNFEVGFRPQRSV	KNDC1	1026	Q76NI1
AGFANRGDVLTGRPF	FBN2	1056	P35556
GSTSDPGNRNRSELF	CYLD	341	Q9NQC7
RPNFQALSGNERFEG	GRIK5	431	Q16478
GGRNEVDPRFISLFS	DNAH10	2576	Q8IVF4
REATSVPRGQGSQFA	PPP1R15A	121	O75807
QAFEFRVGASDRGSP	PCDHB8	526	Q9UN66
LARQGSFRGFPALSQ	NUMB	271	P49757
TRFFAQSGGRLQNPL	PIWIL1	746	Q96J94
APDFVQRGFDSFLGR	UTRN	871	P46939
RGNLRKFQDFSGQDP	UTS2	81	O95399
GIPENQSRSAGSRFS	SSPOP	3596	A2VEC9
GLPVRSVDFNRGTDN	LSAMP	26	Q13449
FTFGPTFRAENSQSR	NARS2	236	Q96I59
FRSRGSGFPFLESEN	TAF1D	126	Q9H5J8
SGNSFDARPSQGYRR	PNMA3	371	Q9UL41
NPFAKGFRDSGRNRT	TBX15	296	Q96SF7
FSNFGPIGTPDNRDR	SMG7	1026	Q92540
SGAVIFNFPGTRNEV	RNF128	141	Q8TEB7
RLASRGQNPAEGSFS	RNF6	216	Q9Y252
GAAGIPRANASRTNF	RNF6	241	Q9Y252
NPSVVQRAFGGFRNE	ST8SIA4	191	Q92187
RGSQGQTERFFPFGL	SIAE	306	Q9HAT2
GDFNFVRRIFPSGNS	TENM1	1211	Q9UKZ4
SQEGQPFRARLSGFF	PKHD1	366	P08F94
RANVSNAGLPGDFRE	NPTX2	146	P47972
KRNGIFPAAAGSRAQ	ARL6IP6	86	Q8N6S5
TPVRNRGDGDGDFQF	CCNB1IP1	221	Q9NPC3
SNRFGNEESFPGRVR	LINC01559	61	Q495D7
RGNFPDRFSARQFPN	TRBV5-5	76	A0A597
SFSRVTNFFRGALQP	TBC1D17	226	Q9HA65
ANFTAGGQPRREEAV	WDR74	31	Q6RFH5
TVAQFRRAQGGFPLS	USP42	1266	Q9H9J4
GFPSSNDLLRFGQFI	WDFY3	1576	Q8IZQ1
VRSGPFGQLFRPDNF	TUBB6	76	Q9BUF5
TLQQSRGFGSFRFPS	VCP	761	P55072
VRSGPFGQVFRPDNF	TUBB8	76	Q3ZCM7
QRNGRTGLFPGSFVE	SH3RF3	866	Q8TEJ3
SRTNPNSGDFRFSLE	RLIM	126	Q9NVW2
SSQEFAQLSPRLGGF	TMPRSS5	171	Q9H3S3
QRQDTFSGTGFFPLD	USP15	931	Q9Y4E8
TFQSPADARAFDRGV	SPRED2	101	Q7Z698
SFFRGRTRPGSFQSL	VIPAS39	111	Q9H9C1
AGGSFDLRRFLTQPQ	SYNGR2	11	O43760
RRVNAFSNFFSGPIV	PTPRC	836	P08575
ELRRSEGNFPNRFSG	TRBV5-3	71	A0A0A0MS03
RALRAAPAGGFQNIA	METTL1	121	Q9UBP6
GRSPNNPFSRVALEF	TTF2	881	Q9UNY4
FQETLRGGSQPDAAR	TTC31	396	Q49AM3
AQREFARGQGTANPE	VPS13D	3416	Q5THJ4
FRFGTVPNGSTERNI	GRIN2B	681	Q13224