Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	TPR domain binding	TRAK1 TRAK2 HSP90AB1	5.93e-06	8	96	3	GO:0030911
GeneOntologyMolecularFunction	ATP-dependent activity	DHX16 ATP6V0A1 MYH7B PEX6 ABCC5 DHX57 ATAD3A DDX54 CARNS1 DNAH9 VCP HSP90AB1	3.80e-05	614	96	12	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX16 PEX6 ABCC5 DHX57 ATAD3A DDX54 CARNS1 DNAH9 VCP HSP90AB1	5.17e-05	441	96	10	GO:0016887
GeneOntologyMolecularFunction	ubiquitin-modified protein reader activity	PEX6 CCDC38 VCP	1.16e-04	20	96	3	GO:0140036
GeneOntologyMolecularFunction	ubiquitin-like protein reader activity	PEX6 CCDC38 VCP	2.29e-04	25	96	3	GO:0140035
GeneOntologyBiologicalProcess	autophagosome assembly	RAB3GAP1 MAP1LC3B2 TRIM32 SNX7 LRBA MAP1LC3B	2.04e-05	121	95	6	GO:0000045
GeneOntologyBiologicalProcess	autophagosome organization	RAB3GAP1 MAP1LC3B2 TRIM32 SNX7 LRBA MAP1LC3B	2.94e-05	129	95	6	GO:1905037
GeneOntologyCellularComponent	axonal growth cone	TRAK1 TRAK2 PARD3 HSP90AB1	5.84e-05	45	98	4	GO:0044295
GeneOntologyCellularComponent	growth cone	FKBP15 RASGRF1 TRAK1 TRAK2 CTNND1 PARD3 HSP90AB1	1.56e-04	245	98	7	GO:0030426
GeneOntologyCellularComponent	site of polarized growth	FKBP15 RASGRF1 TRAK1 TRAK2 CTNND1 PARD3 HSP90AB1	1.90e-04	253	98	7	GO:0030427
Domain	-	DSP EVPL PLEC	2.52e-06	6	95	3	3.90.1290.10
Domain	Plectin_repeat	DSP EVPL PLEC	4.40e-06	7	95	3	IPR001101
Domain	Plectin	DSP EVPL PLEC	4.40e-06	7	95	3	PF00681
Domain	PLEC	DSP EVPL PLEC	4.40e-06	7	95	3	SM00250
Domain	tRNA-bd_arm	KIAA0408 DSP TRAK1 PIBF1	6.17e-06	24	95	4	IPR010978
Domain	Traffickng_kinesin-bd_prot_dom	TRAK1 TRAK2	2.56e-05	2	95	2	IPR022154
Domain	Milton	TRAK1 TRAK2	2.56e-05	2	95	2	PF12448
Domain	DUF1088	NBEA LRBA	2.56e-05	2	95	2	IPR010508
Domain	DUF1088	NBEA LRBA	2.56e-05	2	95	2	PF06469
Domain	HAP1_N	TRAK1 TRAK2	7.65e-05	3	95	2	PF04849
Domain	HAP1_N	TRAK1 TRAK2	7.65e-05	3	95	2	IPR006933
Domain	DUF4704	NBEA LRBA	2.53e-04	5	95	2	IPR031570
Domain	DUF4704	NBEA LRBA	2.53e-04	5	95	2	PF15787
Domain	P-loop_NTPase	DHX16 DLG5 MYH7B PEX6 ABCC5 DHX57 PAPSS1 SEPTIN8 ATAD3A YLPM1 DDX54 DNAH9 VCP	3.54e-04	848	95	13	IPR027417
Domain	PH_BEACH	NBEA LRBA	3.79e-04	6	95	2	PF14844
Domain	-	DHX16 DLG5 PEX6 ABCC5 DHX57 PAPSS1 SEPTIN8 ATAD3A YLPM1 DDX54 DNAH9 VCP	3.95e-04	746	95	12	3.40.50.300
Domain	Spectrin_repeat	DSP EVPL PLEC	4.23e-04	29	95	3	IPR002017
Domain	Arm	ARVCF CTNND1 KPNA1	5.17e-04	31	95	3	PF00514
Domain	Plakophilin/d_Catenin	ARVCF CTNND1	5.29e-04	7	95	2	IPR028435
Domain	Spectrin/alpha-actinin	DSP EVPL PLEC	5.68e-04	32	95	3	IPR018159
Domain	SPEC	DSP EVPL PLEC	5.68e-04	32	95	3	SM00150
Domain	PH-BEACH_dom	NBEA LRBA	7.03e-04	8	95	2	IPR023362
Domain	Atg8	MAP1LC3B2 MAP1LC3B	7.03e-04	8	95	2	PF02991
Domain	-	NBEA LRBA	7.03e-04	8	95	2	2.30.29.40
Domain	Atg8-like	MAP1LC3B2 MAP1LC3B	7.03e-04	8	95	2	IPR004241
Domain	PH_BEACH	NBEA LRBA	7.03e-04	8	95	2	PS51783
Domain	AAA+_ATPase	PEX6 ABCC5 ATAD3A DNAH9 VCP	8.44e-04	144	95	5	IPR003593
Domain	AAA	PEX6 ABCC5 ATAD3A DNAH9 VCP	8.44e-04	144	95	5	SM00382
Domain	BEACH_dom	NBEA LRBA	9.00e-04	9	95	2	IPR000409
Domain	BEACH	NBEA LRBA	9.00e-04	9	95	2	PS50197
Domain	Beach	NBEA LRBA	9.00e-04	9	95	2	PF02138
Domain	-	NBEA LRBA	9.00e-04	9	95	2	1.10.1540.10
Domain	Beach	NBEA LRBA	9.00e-04	9	95	2	SM01026
Domain	ARM_REPEAT	ARVCF CTNND1 KPNA1	1.10e-03	40	95	3	PS50176
Domain	ARM	ARVCF CTNND1 KPNA1	1.10e-03	40	95	3	SM00185
Domain	Armadillo	ARVCF CTNND1 KPNA1	1.76e-03	47	95	3	IPR000225
Domain	AAA	PEX6 ATAD3A VCP	2.35e-03	52	95	3	PF00004
Domain	ATPase_AAA_core	PEX6 ATAD3A VCP	2.62e-03	54	95	3	IPR003959
Domain	DUF1605	DHX16 DHX57	3.31e-03	17	95	2	IPR011709
Domain	OB_NTP_bind	DHX16 DHX57	3.31e-03	17	95	2	PF07717
Domain	HA2	DHX16 DHX57	3.71e-03	18	95	2	SM00847
Domain	HA2	DHX16 DHX57	3.71e-03	18	95	2	PF04408
Domain	Helicase-assoc_dom	DHX16 DHX57	3.71e-03	18	95	2	IPR007502
Domain	Prefoldin	ATP6V0A1 DSP TRAK2	5.90e-03	72	95	3	IPR009053
Domain	DEAD/DEAH_box_helicase_dom	DHX16 DHX57 DDX54	6.13e-03	73	95	3	IPR011545
Domain	DEAD	DHX16 DHX57 DDX54	6.13e-03	73	95	3	PF00270
Domain	-	ITGB5 ITIH3 SEC24C	6.37e-03	74	95	3	3.40.50.410
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ATP6V0A1 DSP SH3GLB2 ABCC5 NBEA ACTR3B BRWD3 ARCN1 RNF220 TRIM32 NFE2L2 YLPM1 PLEC LRBA TXLNG VCP SH3BP5 KPNA1 HSP90AB1	2.89e-09	1285	98	19	35914814
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DHX16 DSP ARCN1 PHB1 LUC7L PBRM1 SEC24C ATAD3A YLPM1 DDX54 PLEC CTNND1 CDC5L STX7 VCP CPSF7 HSP90AB1	4.01e-09	1024	98	17	24711643
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DHX16 FKBP15 DLG5 DSP DHX57 PHB1 LUC7L SEC24C ATAD3A TRIM32 YLPM1 PLEC CDC5L PZP VCP CPSF7 HSP90AB1	9.05e-09	1082	98	17	38697112
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DSP MAP7 ARCN1 LUC7L SEC24C LRRC1 YLPM1 PLEC CTNND1 CDC5L KPNA1 CPSF7 HSP90AB1	1.04e-08	582	98	13	20467437
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	KIAA0408 DSP LAMA2 SH3GLB2 ITGB5 LUC7L XIRP2 TRIM32 PLEC PARD3 VCP HSP90AB1	1.70e-08	497	98	12	23414517
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX16 DSP DHX57 ARCN1 PHB1 RAB3GAP1 SEC24C ARVCF ATAD3A TRIM32 DDX54 PLEC CTNND1 CDC5L PARD3 VCP KPNA1 HSP90AB1	4.00e-08	1353	98	18	29467282
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DLG5 DSP ABCC5 ARCN1 PHB1 SEC24C ATAD3A LRBA CTNND1 PARD3 MAP3K21 VCP HSP90AB1	1.02e-07	708	98	13	39231216
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	ATP6V0A1 TMEM237 DSP MAP7 ITIH3 PHB1 ATAD3A PLEC CTNND1 CDC5L STX7 HSP90AB1	1.41e-07	604	98	12	37616343
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	DHX16 DLG5 TMEM237 DSP DHX57 ITIH3 ARCN1 LUC7L PBRM1 SEC24C YLPM1 PLEC CTNND1 PARD3 VCP CPSF7 HSP90AB1	2.71e-07	1371	98	17	36244648
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	DSP LUC7L SEC24C ATAD3A CTNND1 CDC5L VCP KPNA1 CPSF7	2.84e-07	315	98	9	26777405
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	DSP MYH7B ACTR3B ARCN1 PHB1 SEC24C ATAD3A TRIM32 PLEC LRBA PZP VCP	2.94e-07	647	98	12	26618866
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	DHX16 DHX57 MAP7 ARCN1 PHB1 LUC7L YLPM1 DDX54 CDC5L TXLNG VCP CPSF7	3.24e-07	653	98	12	33742100
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	TMEM237 ABCC5 ITGB5 ARCN1 PHB1 RAB3GAP1 SEC24C DEF6 DDX54 LRBA CTNND1 STX7 ILVBL HSP90AB1	4.67e-07	952	98	14	38569033
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ATP6V0A1 DSP DHX57 NBEA ACTR3B MAP7 ARCN1 SEPTIN8 SEC24C ARVCF ATAD3A PLEC CTNND1 CDC5L VCP CPSF7 HSP90AB1	4.92e-07	1431	98	17	37142655
Pubmed	Anthracyclines induce DNA damage response-mediated protection against severe sepsis.	MAP1LC3B2 NFE2L2 MAP1LC3B	7.53e-07	7	98	3	24184056
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DLG5 ATP6V0A1 TMEM237 MAP7 PHB1 RAB3GAP1 SEC24C ATAD3A LRRC1 DDX54 CTNND1 CDC5L PARD3 PIBF1 STX7 TXLNG VCP	8.35e-07	1487	98	17	33957083
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	DHX16 DHX57 MAP7 TRAK1 PHB1 LUC7L TRAK2 CTNND1 VCP KPNA1 CPSF7 HSP90AB1	9.46e-07	723	98	12	34133714
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	DSP MAP7 PBRM1 CEP112 DEF6 PLEC KPNA1 HSP90AB1	1.08e-06	272	98	8	31010829
Pubmed	αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells.	ITGB5 MAP1LC3B2 MAP1LC3B	1.20e-06	8	98	3	26965188
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	DHX57 NBEA PHB1 XIRP2 CROCC2 DDX54 LRBA CTNND1 RIC1 CPSF7	1.48e-06	497	98	10	36774506
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	FKBP15 DSP NBEA RAB3GAP1 PLEC CTNND1 VCP HSP90AB1	1.66e-06	288	98	8	23383273
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	DLG5 WWC3 PAPSS1 ARCN1 LUC7L SEC24C ARVCF ATAD3A DDX54 CTNND1 CDC5L PARD3 VCP CPSF7 HSP90AB1	2.15e-06	1247	98	15	27684187
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DHX16 DLG5 DSP EVPL MAP7 ARCN1 PHB1 ATAD3A DDX54 PLEC CTNND1 CDC5L KPNA1 CPSF7 HSP90AB1	2.37e-06	1257	98	15	36526897
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	FKBP15 DSP ARCN1 PHB1 SEC24C ATAD3A YLPM1 PLEC CDC5L VCP KPNA1 HSP90AB1	3.02e-06	809	98	12	32129710
Pubmed	Network organization of the human autophagy system.	SH3GLB2 PHB1 RAB3GAP1 XIRP2 YLPM1 CTNND1 MAP1LC3B STX7 ILVBL	4.22e-06	437	98	9	20562859
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	DHX16 IRAK1BP1 ARCN1 PHB1 LUC7L PBRM1 SEC24C ATAD3A DDX54 PLEC LRBA CDC5L ILVBL KPNA1 HSP90AB1	4.22e-06	1318	98	15	30463901
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	DHX16 DLG5 EVPL CBX6 NFE2L2 CEP112 PIBF1 CPSF7	4.43e-06	329	98	8	34316702
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	KIAA0408 PPM1E NBEA TRAK1 CDC5L SH3BP5	4.59e-06	151	98	6	17043677
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	DSP MYH7B LAMA2 PHB1 ARVCF ATAD3A PLEC HSP90AB1	4.63e-06	331	98	8	29199018
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	FKBP15 DSP ACTR3B ARCN1 TCHH ATAD3A TRIM32 PLEC CTNND1 VCP KPNA1 HSP90AB1	4.64e-06	844	98	12	25963833
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DSP PBRM1 DDX54 PLEC LRBA CDC5L HSP90AB1	4.69e-06	234	98	7	36243803
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 DSP MAP7 TRAK1 LUC7L CEP112 OTUD7A PLEC CTNND1 PARD3 PIBF1 MAP3K21	5.68e-06	861	98	12	36931259
Pubmed	Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC).	LAMA2 CTNND1 VCP	6.08e-06	13	98	3	16212419
Pubmed	Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.	DSP XIRP2 CTNND1	7.72e-06	14	98	3	17766470
Pubmed	Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	25421500
Pubmed	Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	27265145
Pubmed	Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	20889906
Pubmed	Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	38656870
Pubmed	Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	12088839
Pubmed	Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	22968077
Pubmed	[Preparation of an autophagy-targeted antituberculosis DNA vaccine encoding LpqH fused with LC3].	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	24909277
Pubmed	Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	28928467
Pubmed	The Bin/amphiphysin/Rvs (BAR) domain protein endophilin B2 interacts with plectin and controls perinuclear cytoskeletal architecture.	SH3GLB2 PLEC	7.86e-06	2	98	2	23921385
Pubmed	Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	37047689
Pubmed	Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networks.	TRAK1 TRAK2	7.86e-06	2	98	2	20230862
Pubmed	Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	32057231
Pubmed	Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	30349463
Pubmed	Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	31431059
Pubmed	Localization of the kinesin adaptor proteins trafficking kinesin proteins 1 and 2 in primary cultures of hippocampal pyramidal and cortical neurons.	TRAK1 TRAK2	7.86e-06	2	98	2	25653102
Pubmed	Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B).	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	31577510
Pubmed	LC3 conjugation system in mammalian autophagy.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	15325588
Pubmed	LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy.	MAP1LC3B2 MAP1LC3B	7.86e-06	2	98	2	37315562
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DSP DUSP4 PPM1E NBEA ARVCF LRRC1 YLPM1 DDX54 CTNND1 CDC5L PIBF1 KPNA1 HSP90AB1	7.98e-06	1049	98	13	27880917
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	DSP DHX57 ACTR3B ITIH3 PBRM1 CDC5L PARD3 PZP VCP	8.24e-06	475	98	9	31040226
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	DSP PHB1 LUC7L PBRM1 ATAD3A YLPM1 DDX54 CDC5L KPNA1 HSP90AB1	8.37e-06	605	98	10	28977666
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	DSP MAP7 ARCN1 PHB1 LUC7L SEC24C ATAD3A DDX54 PLEC CTNND1 CDC5L TXLNG VCP KPNA1 HSP90AB1	9.85e-06	1415	98	15	28515276
Pubmed	Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown.	MAP1LC3B2 MAP1LC3B VCP	1.18e-05	16	98	3	29719249
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	FKBP15 PEX6 DHX57 NBEA DDX54 LRBA CTNND1 STX7 RIC1	1.32e-05	504	98	9	34432599
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ARCN1 PHB1 SEC24C ATAD3A PLEC LRBA CDC5L VCP CPSF7 HSP90AB1	1.32e-05	638	98	10	33239621
Pubmed	Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	TMEM237 EVC TRIM32 CC2D2A	1.45e-05	52	98	4	20301743
Pubmed	KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.	DSP DHX57 PHB1 DDX54 VCP KPNA1 HSP90AB1	1.54e-05	281	98	7	26725010
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DHX16 DSP DHX57 PBRM1 SEC24C ATAD3A YLPM1 DDX54 PLEC VCP	1.62e-05	653	98	10	22586326
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	DSP LUC7L ATAD3A YLPM1 DDX54 PLEC CTNND1 CDC5L ILVBL HSP90AB1	1.66e-05	655	98	10	35819319
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	FKBP15 NBEA PBRM1 SEC24C ARVCF YLPM1 CTNND1 CDC5L PARD3 SH3BP5 KPNA1 HSP90AB1	1.73e-05	963	98	12	28671696
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	FKBP15 DSP NBEA ACTR3B ARCN1 PHB1 SEPTIN8 RAB3GAP1 ATAD3A PLEC CTNND1 VCP HSP90AB1	1.90e-05	1139	98	13	36417873
Pubmed	Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice.	TRAK1 TRAK2	2.35e-05	3	98	2	16380713
Pubmed	Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin α.	CDC5L KPNA1	2.35e-05	3	98	2	24269683
Pubmed	The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.	NBEA LRBA	2.35e-05	3	98	2	28814779
Pubmed	Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope.	DSP EVPL	2.35e-05	3	98	2	9651377
Pubmed	The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	28291748
Pubmed	Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	27636016
Pubmed	Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	28598240
Pubmed	TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites.	TRAK1 TRAK2	2.35e-05	3	98	2	23395375
Pubmed	Autophagy plays an essential role in cigarette smoke-induced expression of MUC5AC in airway epithelium.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	27036871
Pubmed	Microtubule-Associated Protein 1 Light Chain 3 (LC3) Isoforms in RPE and Retina.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	29721994
Pubmed	HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	29088262
Pubmed	Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	24095928
Pubmed	Nrf2 is not required for epithelial prohibitin-dependent attenuation of experimental colitis.	PHB1 NFE2L2	2.35e-05	3	98	2	23494124
Pubmed	Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.	DLG5 SLC22A4	2.35e-05	3	98	2	15955786
Pubmed	Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2.	NFE2L2 KPNA1	2.35e-05	3	98	2	18238777
Pubmed	Autophagy proteins are modulated in the liver and hypothalamus of the offspring of mice with diet-induced obesity.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	27180121
Pubmed	Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin.	DSP EVPL	2.35e-05	3	98	2	9412476
Pubmed	ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	33459130
Pubmed	BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	33459136
Pubmed	Autophagy is required and protects against apoptosis during myoblast differentiation.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	24865278
Pubmed	Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	18069693
Pubmed	BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy.	MAP1LC3B2 MAP1LC3B	2.35e-05	3	98	2	24591579
Pubmed	The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche.	DSP MAP1LC3B2 MAP1LC3B	2.39e-05	20	98	3	33529466
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	DSP MAP7 PHB1 SEC24C PLEC CDC5L VCP CPSF7 HSP90AB1	2.66e-05	551	98	9	34728620
Pubmed	Prohibitin regulates TGF-beta induced apoptosis as a downstream effector of Smad-dependent and -independent signaling.	PHB1 PLEC HSP90AB1	2.78e-05	21	98	3	19725029
Pubmed	ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.	MAP1LC3B2 MAP1LC3B PARD3	2.78e-05	21	98	3	30985297
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	DSP PHB1 RAB3GAP1 ATAD3A PLEC VCP HSP90AB1	3.01e-05	312	98	7	37120454
Pubmed	DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.	DSP ATAD3A PLEC HSP90AB1	3.11e-05	63	98	4	37052853
Pubmed	Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta.	MAP1LC3B2 NFE2L2 MAP1LC3B	3.21e-05	22	98	3	27383629
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	DLG5 SH3GLB2 EVPL ARVCF PLEC CTNND1 ARHGAP18 PARD3 HSP90AB1	3.23e-05	565	98	9	25468996
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	DSP ARCN1 PHB1 ATAD3A DDX54 PLEC CTNND1 VCP CPSF7 HSP90AB1	3.33e-05	711	98	10	33022573
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	TMEM237 ABCC5 ARVCF SLC22A4 LRBA CTNND1 PARD3 STX7 TXLNG	3.41e-05	569	98	9	30639242
Pubmed	New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity.	DSP CTNND1 PARD3	3.69e-05	23	98	3	18809908
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	DSP SEC24C ATAD3A YLPM1 CDC5L CPSF7	3.88e-05	220	98	6	24550385
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	NBEA ARCN1 PHB1 RAB3GAP1 ATAD3A LRBA CTNND1 VCP	4.14e-05	449	98	8	31732153
Interaction	RHOB interactions	DLG5 TMEM237 ABCC5 NBEA ITGB5 PHB1 ARVCF ATAD3A SLC22A4 LRRC1 CTNND1 ARHGAP18 PARD3 STX7 MAP3K21 VCP KPNA1	4.16e-07	840	96	17	int:RHOB
Interaction	CDC5L interactions	DHX16 DSP TRIM31 MAP7 ARCN1 TRAK1 PHB1 LUC7L SEC24C LRRC1 YLPM1 PLEC CTNND1 CDC5L SH3BP5 CPSF7 HSP90AB1	5.32e-07	855	96	17	int:CDC5L
Interaction	CDC42 interactions	DLG5 ATP6V0A1 TMEM237 DSP SH3GLB2 ABCC5 MUC12 PHB1 SEPTIN8 SEC24C ATAD3A SLC22A4 DEF6 DDX54 CTNND1 CDC5L PARD3 STX7 ILVBL VCP KPNA1	8.38e-07	1323	96	21	int:CDC42
Interaction	RND2 interactions	DLG5 ATP6V0A1 PHB1 RAB3GAP1 SLC22A4 LRRC1 LRBA CTNND1 PARD3 STX7 VCP KPNA1	1.20e-06	440	96	12	int:RND2
Interaction	JUP interactions	DSP DUSP4 TRIM31 ARCN1 ZUP1 PHB1 PLEC CTNND1 PARD3 STX7 VCP HSP90AB1	3.30e-06	485	96	12	int:JUP
Interaction	DIRAS3 interactions	DLG5 NBEA PHB1 CBX6 LRBA CTNND1 PARD3 MAP3K21 VCP	4.47e-06	262	96	9	int:DIRAS3
Interaction	TRIM21 interactions	DSP TRIM31 PHB1 LUC7L RAB3GAP1 ATAD3A YLPM1 OTUD7A PLEC CDC5L MAP1LC3B ILVBL VCP HSP90AB1	4.69e-06	689	96	14	int:TRIM21
Interaction	OBSL1 interactions	DHX16 DSP DHX57 PHB1 PBRM1 SEC24C ATAD3A CROCC2 LRRC1 YLPM1 DDX54 PLEC CDC5L VCP CPSF7 HSP90AB1	5.22e-06	902	96	16	int:OBSL1
Interaction	ANK3 interactions	DLG5 ARVCF OTUD7A PLEC CTNND1 MAP1LC3B STX7 HSP90AB1	5.33e-06	201	96	8	int:ANK3
Interaction	RHOH interactions	DLG5 ATP6V0A1 TMEM237 ABCC5 PHB1 ATAD3A SLC22A4 LRBA CTNND1 PARD3 VCP KPNA1	5.73e-06	512	96	12	int:RHOH
Interaction	CAV1 interactions	DLG5 ABCC5 ARCN1 PHB1 ARVCF MAP1LC3B2 SLC22A4 LRRC1 LRBA CTNND1 PARD3 STX7 RIC1 VCP	8.24e-06	724	96	14	int:CAV1
Interaction	RHOA interactions	DLG5 ATP6V0A1 RASGRF1 TMEM237 SH3GLB2 ABCC5 PHB1 RAB3GAP1 ATAD3A SLC22A4 DEF6 DDX54 CTNND1 MAP1LC3B PARD3 STX7 VCP KPNA1	1.25e-05	1199	96	18	int:RHOA
Interaction	KCNA3 interactions	DLG5 DSP MYH7B ABCC5 ARCN1 PHB1 SEC24C ATAD3A CEP112 LRBA CTNND1 PARD3 MAP3K21 VCP HSP90AB1	1.51e-05	871	96	15	int:KCNA3
Interaction	RAC2 interactions	ATP6V0A1 TMEM237 ABCC5 ITGB5 PHB1 SLC22A4 DEF6 DDX54 CTNND1 PARD3 STX7 VCP KPNA1	1.84e-05	674	96	13	int:RAC2
Interaction	RHOC interactions	DLG5 ATP6V0A1 TMEM237 ABCC5 ITGB5 SLC22A4 DDX54 CTNND1 PARD3 STX7 VCP KPNA1	2.13e-05	584	96	12	int:RHOC
Interaction	YWHAG interactions	KIAA0408 DLG5 DSP MAP7 TRAK1 LUC7L TRIM32 CEP112 OTUD7A LRBA CTNND1 CDC5L MAP1LC3B PARD3 PIBF1 MAP3K21 VCP HSP90AB1	2.15e-05	1248	96	18	int:YWHAG
Interaction	MECP2 interactions	DHX16 FKBP15 DLG5 DSP DHX57 PHB1 LUC7L SEC24C ATAD3A TRIM32 YLPM1 DDX54 PLEC CDC5L PZP VCP CPSF7 HSP90AB1	3.23e-05	1287	96	18	int:MECP2
Interaction	CTNND1 interactions	RASGRF1 TRIM31 ARVCF CTNND1 CDC5L PARD3 STX7 VCP	3.93e-05	265	96	8	int:CTNND1
Interaction	MIDN interactions	ATP6V0A1 TMEM237 DSP MAP7 ITIH3 PHB1 ATAD3A PLEC CTNND1 CDC5L STX7 HSP90AB1	4.20e-05	626	96	12	int:MIDN
Interaction	EED interactions	ATP6V0A1 DSP ARCN1 PHB1 RAB3GAP1 PBRM1 SEC24C XIRP2 SNX7 YLPM1 DDX54 PLEC CTNND1 CDC5L MAP1LC3B VCP KPNA1 CPSF7 HSP90AB1	4.39e-05	1445	96	19	int:EED
Interaction	FBXO22 interactions	DHX57 NBEA PHB1 XIRP2 CROCC2 DDX54 LRBA CTNND1 MAP1LC3B RIC1 CPSF7	5.21e-05	540	96	11	int:FBXO22
Interaction	YWHAH interactions	DLG5 DSP MAP7 TRAK1 TRIM32 CEP112 OTUD7A CC2D2A PLEC LRBA CTNND1 PARD3 PIBF1 MAP3K21 VCP HSP90AB1	6.08e-05	1102	96	16	int:YWHAH
Interaction	RICTOR interactions	DSP SH3GLB2 ZUP1 PHB1 RAB3GAP1 PBRM1 SEC24C ATAD3A PLEC CDC5L STX7 VCP HSP90AB1	6.26e-05	759	96	13	int:RICTOR
Interaction	H1-5 interactions	DSP LAMA2 ABCC5 DHX57 BRWD3 PBRM1 XIRP2 CBX6 MAP1LC3B VCP	7.19e-05	463	96	10	int:H1-5
Interaction	YWHAQ interactions	DLG5 TRIM31 MAP7 TRAK1 PHB1 TRIM32 CEP112 OTUD7A PLEC LRBA CTNND1 CDC5L PARD3 MAP3K21 VCP HSP90AB1	7.21e-05	1118	96	16	int:YWHAQ
Interaction	AP2B1 interactions	KIAA0408 FKBP15 DLG5 TRIM31 RAB3GAP1 SEC24C ARHGAP18 MAP1LC3B VCP	7.27e-05	373	96	9	int:AP2B1
Interaction	MAPT interactions	ATP6V0A1 MYH7B PPM1E SH3GLB2 PHB1 SEPTIN8 RAB3GAP1 PBRM1 SEC24C CTNND1 MAP1LC3B STX7 VCP KPNA1 CPSF7 HSP90AB1	7.29e-05	1119	96	16	int:MAPT
Interaction	RAB2A interactions	TMEM237 ABCC5 NBEA ITGB5 PHB1 SEC24C CTNND1 MAP1LC3B STX7 VCP HSP90AB1	8.05e-05	567	96	11	int:RAB2A
Interaction	RHOF interactions	DLG5 ATP6V0A1 TMEM237 ABCC5 PHB1 ARVCF ATAD3A SLC22A4 DDX54 PARD3 VCP KPNA1	8.39e-05	673	96	12	int:RHOF
Interaction	RHOD interactions	DLG5 TMEM237 ABCC5 PHB1 RAB3GAP1 SLC22A4 LRBA CTNND1 PARD3 STX7 VCP	8.71e-05	572	96	11	int:RHOD
Interaction	GRWD1 interactions	DSP TRIM31 MAP7 PHB1 LUC7L ATAD3A CDC5L VCP HSP90AB1	1.02e-04	390	96	9	int:GRWD1
Interaction	TMEM17 interactions	TMEM237 ABCC5 NBEA ARCN1 DDX54 LRBA CTNND1 PARD3 STX7	1.33e-04	404	96	9	int:TMEM17
Interaction	OR8B8 interactions	PBRM1 YLPM1	1.34e-04	4	96	2	int:OR8B8
Interaction	RAC1 interactions	DLG5 RASGRF1 TMEM237 ABCC5 ITGB5 PHB1 ATAD3A SLC22A4 DEF6 LRBA CTNND1 PARD3 STX7 VCP KPNA1	1.45e-04	1063	96	15	int:RAC1
Interaction	COPA interactions	TMEM237 TRIM31 ARCN1 PHB1 RAB3GAP1 SEC24C CDC5L ILVBL VCP	1.54e-04	412	96	9	int:COPA
Interaction	LYN interactions	DLG5 DSP DUSP4 ABCC5 CBX6 LRRC1 CTNND1 PLEKHH2 PARD3 STX7 MAP3K21 HSP90AB1	1.58e-04	720	96	12	int:LYN
Interaction	TJP1 interactions	DHX16 DLG5 ZUP1 ARVCF OTUD7A PLEC PARD3 CPSF7	1.63e-04	325	96	8	int:TJP1
Interaction	CFTR interactions	B3GNT9 TMEM237 DSP MYH7B ACTR3B ITGB5 ARCN1 ZUP1 PHB1 SEC24C ATAD3A TRIM32 PLEC LRBA CTNND1 PZP VCP HSP90AB1	1.93e-04	1480	96	18	int:CFTR
Interaction	INSIG2 interactions	TMEM237 DSP ARCN1 XIRP2 VCP HSP90AB1	2.03e-04	177	96	6	int:INSIG2
Interaction	HDLBP interactions	DHX16 DLG5 TMEM237 DSP DHX57 LUC7L SEC24C YLPM1 CDC5L ARHGAP18 PARD3 VCP CPSF7	2.05e-04	855	96	13	int:HDLBP
Interaction	PPP1R3A interactions	XIRP2 CBX6 YLPM1 VCP	2.62e-04	65	96	4	int:PPP1R3A
Interaction	KRT10 interactions	TRIM31 EVPL ZUP1 PHB1 MAP1LC3B VCP	2.73e-04	187	96	6	int:KRT10
Interaction	YWHAE interactions	DLG5 RASGRF1 MAP7 TRAK1 PHB1 TRIM32 CEP112 DDX54 LRBA CTNND1 CDC5L MAP1LC3B PARD3 MAP3K21 VCP HSP90AB1	2.75e-04	1256	96	16	int:YWHAE
Interaction	ZFPL1 interactions	DLG5 TMEM237 NBEA ARCN1 LRBA CTNND1 PARD3 STX7 RIC1	2.87e-04	448	96	9	int:ZFPL1
Interaction	RAB7A interactions	FKBP15 ATP6V0A1 PEX6 DHX57 NBEA PHB1 DDX54 LRBA CTNND1 MAP1LC3B STX7 RIC1 VCP	2.89e-04	886	96	13	int:RAB7A
Interaction	NEFM interactions	DLG5 DSP MAP7 PLEC PIBF1 DNAH9	2.98e-04	190	96	6	int:NEFM
Interaction	KRT14 interactions	DSP TRIM31 EVPL ZUP1 PLEC VCP	3.15e-04	192	96	6	int:KRT14
Interaction	MAP3K10 interactions	PHB1 OTUD7A MAP3K21 HSP90AB1	3.30e-04	69	96	4	int:MAP3K10
Interaction	DTNA interactions	PHB1 SEC24C PARD3 STX7 HSP90AB1	3.30e-04	125	96	5	int:DTNA
Interaction	GSK3A interactions	DLG5 MAP7 TRAK1 DDX54 TRAK2 CTNND1 MAP1LC3B VCP HSP90AB1	3.71e-04	464	96	9	int:GSK3A
Interaction	SVIP interactions	STX7 VCP HSP90AB1	3.87e-04	30	96	3	int:SVIP
Interaction	DMXL2 interactions	ZUP1 RAB3GAP1 SLC22A4 HSP90AB1	3.88e-04	72	96	4	int:DMXL2
Cytoband	Ensembl 112 genes in cytogenetic band chr6q22	KIAA0408 LAMA2 ZUP1 ARHGAP18	1.65e-04	127	98	4	chr6q22
GeneFamily	EF-hand domain containing\|Plakins	DSP EVPL PLEC	1.92e-06	8	60	3	939
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEA LRBA	3.84e-04	9	60	2	1230
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ARVCF CTNND1 KPNA1	3.90e-04	43	60	3	409
GeneFamily	AAA ATPases	PEX6 ATAD3A VCP	7.23e-04	53	60	3	413
GeneFamily	DEAH-box helicases	DHX16 DHX57	1.26e-03	16	60	2	500
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP3 NBEA	4.15e-03	29	60	2	396
GeneFamily	Autophagy related	MAP1LC3B2 MAP1LC3B	5.35e-03	33	60	2	1022
Coexpression	GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP	ATP6V0A1 DUSP4 NBEA PAPSS1 ITGB5 BRWD3 CTNND1	6.29e-06	187	97	7	M6807
Coexpression	GSE27786_LSK_VS_NEUTROPHIL_UP	PAPSS1 LUC7L RNF220 CBX6 LRRC1 ARHGAP18 VCP	9.75e-06	200	97	7	M4760
Coexpression	GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_UP	MEIS3 CBX6 NFE2L2 ARHGAP18 PIBF1 CCDC171 SH3BP5	9.75e-06	200	97	7	M9293
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	ANO4 DLG5 PPM1E LAMA2 ABCC5 ARHGAP18	3.43e-06	187	97	6	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE KIAA0408 LAMA2 PLEKHH2 DNAH9	2.64e-05	160	97	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE KIAA0408 LAMA2 PLEKHH2 DNAH9	2.64e-05	160	97	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	KIAA0408 RASGRF1 PAPSS1 SLC22A4 TRAK2	3.34e-05	168	97	5	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	ABCC5 NFE2L2 LRRC1 CTNND1 PARD3	4.06e-05	175	97	5	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	Ciliated_cells-A-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	DLG5 TRIM31 PLEKHH2 PARD3 DNAH9	4.52e-05	179	97	5	1c41314b6fcfcac8d62034e7037570120d58f20f
ToppCell	COVID-19-kidney-CD-IC-B\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANO4 TRHDE DLG5 PPM1E MAP7	4.89e-05	182	97	5	ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DSP EVPL MAP7 RNF220 MAP3K21	5.42e-05	186	97	5	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PBRM1 ATAD3A SNX7 CC2D2A PIBF1	5.99e-05	190	97	5	36e83995021ba16690f84e2077a9e8baec547d05
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PBRM1 ATAD3A SNX7 CC2D2A PIBF1	5.99e-05	190	97	5	d26be9e1b676f750e716b91ebc3598fac3735612
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 DSP LAMA2 XIRP2 CEP112	5.99e-05	190	97	5	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	Mild/Remission-B_naive-11\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DSP SNX7 PIBF1 STX7 SH3BP5	6.15e-05	191	97	5	ebb165096de301ba663703d1662d9413ea317867
ToppCell	Mild/Remission-B_naive-11\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DSP SNX7 PIBF1 STX7 SH3BP5	6.30e-05	192	97	5	c6f325cddce43b72f013b21dfffc9987fd68b6a7
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIAA0408 RASGRF1 MAP7 CARNS1 SH3BP5	6.46e-05	193	97	5	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE EVC MAP7 LRBA MAP3K21	6.61e-05	194	97	5	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RASGRF1 DSP EVPL MAP7 MAP3K21	6.61e-05	194	97	5	c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RASGRF1 DSP EVPL MAP7 MAP3K21	6.78e-05	195	97	5	f08e41706680881ebd0afcd08a02f8ac0089f04e
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RASGRF1 DSP EVPL MAP7 MAP3K21	6.78e-05	195	97	5	62d369a8af2b76a2553bc8ff9cb89a133b060123
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RASGRF1 DSP EVPL MAP7 MAP3K21	6.94e-05	196	97	5	75e9e430a4f55ef10f2e3132afa690fc8bfaff83
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RASGRF1 DSP EVPL MAP7 MAP3K21	6.94e-05	196	97	5	0a34a0009f479384f1994c6f977f942699a132c8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE EVC MAP7 LRBA MAP3K21	6.94e-05	196	97	5	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RASGRF1 DSP EVPL MAP7 MAP3K21	6.94e-05	196	97	5	00bef0e47739932fd1da109cd607de0789d14ca5
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RASGRF1 DSP EVPL MAP7 MAP3K21	7.11e-05	197	97	5	6852a8ec1397811bbdd1fc625c52ed4fa75a931e
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RASGRF1 DSP EVPL MAP7 MAP3K21	7.11e-05	197	97	5	2f91b3870a7058168093a143110954c07588cfe9
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANO4 KIAA0408 LAMA2 PZP CCDC171	7.46e-05	199	97	5	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE KIAA0408 B3GNT9 PLEKHH2 PZP	7.64e-05	200	97	5	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	ANO4 KIAA0408 LAMA2 MEIS3 PZP	7.64e-05	200	97	5	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	ANO4 KIAA0408 LAMA2 NBEA PZP	7.64e-05	200	97	5	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE KIAA0408 B3GNT9 PLEKHH2 PZP	7.64e-05	200	97	5	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
Drug	Sulfanilamide [63-74-1]; Down 200; 23.2uM; HL60; HT_HG-U133A	ATP6V0A1 DUSP4 PEX6 SH3GLB2 TRAK1 DDX54 CTNND1 CDC5L	2.04e-06	197	97	8	2709_DN
Disease	1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6) measurement	SYCP2L PEX6	1.53e-04	6	95	2	EFO_0800449
Disease	2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA) measurement	PEX6 CARNS1	1.53e-04	6	95	2	EFO_0800111
Disease	systolic blood pressure, response to low sodium diet	IRAK1BP1 PIBF1	2.13e-04	7	95	2	EFO_0005402, EFO_0006335
Disease	Joubert syndrome (implicated_via_orthology)	TMEM237 CC2D2A	2.13e-04	7	95	2	DOID:0050777 (implicated_via_orthology)
Disease	Arima syndrome	TMEM237 CC2D2A	2.13e-04	7	95	2	C1855675
Disease	retinal vasculature measurement	DHX16 LAMA2 MUC12 COG8 SEPTIN8 XIRP2 CEP112 DNAH9	2.70e-04	517	95	8	EFO_0010554
Disease	creatinine measurement	MYH7B LAMA2 EVC BRWD3 COQ10A NFE2L2 SLC22A4 PLEC CTNND1 PLEKHH2 PARD3	3.58e-04	995	95	11	EFO_0004518
Disease	22q11 partial monosomy syndrome	SEC24C ARVCF	3.64e-04	9	95	2	C3266101
Disease	gamma-glutamylisoleucine measurement	LAMA2 CARNS1	3.64e-04	9	95	2	EFO_0021139
Disease	Ciliopathies	TMEM237 EVC TRIM32 CC2D2A	4.48e-04	110	95	4	C4277690
Disease	Asymmetric crying face association	SEC24C ARVCF	4.54e-04	10	95	2	C0431406
Disease	22q11 Deletion Syndrome	SEC24C ARVCF	4.54e-04	10	95	2	C2936346
Disease	Polydactyly	TMEM237 EVC TRIM32 CC2D2A	5.66e-04	117	95	4	C0152427
Disease	Dental enamel hypoplasia	MYH7B MAP3K21	6.63e-04	12	95	2	EFO_1001304
Disease	mosquito bite reaction itch intensity measurement	TRIM31 SEPTIN8 TCHH SLC22A4	8.16e-04	129	95	4	EFO_0008377
Disease	Autosomal recessive limb-girdle muscular dystrophy	TRIM32 PLEC	9.10e-04	14	95	2	cv:C2931907
Disease	Myopia	RASGRF1 LAMA2	1.05e-03	15	95	2	C0027092
Disease	DiGeorge Syndrome	SEC24C ARVCF	1.20e-03	16	95	2	C0012236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	SEC24C ARVCF	1.20e-03	16	95	2	C0795907
Disease	Shprintzen syndrome	SEC24C ARVCF	1.20e-03	16	95	2	C0220704
Disease	muscular dystrophy (is_implicated_in)	LAMA2 TRIM32	1.35e-03	17	95	2	DOID:9884 (is_implicated_in)
Disease	autism spectrum disorder (implicated_via_orthology)	NBEA ARVCF LRBA CTNND1	1.50e-03	152	95	4	DOID:0060041 (implicated_via_orthology)
Disease	non-melanoma skin carcinoma	TMEM237 MYH7B TRIM31 TRAK2 PARD3	1.69e-03	265	95	5	EFO_0009260
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	PBRM1 HSP90AB1	1.69e-03	19	95	2	DOID:4928 (is_marker_for)
Disease	cancer (implicated_via_orthology)	ITGB5 CBX6 LRRC1 STX7 HSP90AB1	1.77e-03	268	95	5	DOID:162 (implicated_via_orthology)
Disease	Familial aplasia of the vermis	TMEM237 CC2D2A	1.88e-03	20	95	2	cv:C0431399
Disease	Joubert syndrome 1	TMEM237 PIBF1	2.07e-03	21	95	2	C4551568
Disease	nose morphology measurement, mouth morphology measurement	ANO4 MEIS3	2.07e-03	21	95	2	EFO_0007843, EFO_0007955
Disease	Ataxia	ARCN1 PIBF1	2.93e-03	25	95	2	C0004134
Disease	mean corpuscular hemoglobin concentration	ABCC5 ITGB5 PHB1 LUC7L NFE2L2 CC2D2A PIBF1 STX7 KPNA1 HSP90AB1	2.96e-03	1105	95	10	EFO_0004528
Disease	Limb-girdle muscular dystrophy	TRIM32 PLEC	3.17e-03	26	95	2	cv:C0686353

Protein segments in the cluster

Peptide	Gene	Start	Entry
RVAVEKVQLAEDRAF	TRHDE	186	Q9UKU6
ADVDARKQAIRDAER	CDC5L	516	Q99459
VKEQEARFERLTRAL	ARVCF	16	O00192
SRLIAAFEQKERERE	CBX6	51	O95503
RRETELEDARQKFRS	SH3BP5	61	O60239
RVEAEARARAKAERE	ATAD3A	236	Q9NVI7
AIRESAKVVDQAQRR	ACTR3B	36	Q9P1U1
FSTQREERLRKEFEA	CCDC171	261	Q6TFL3
AAERRLQDVRQKFED	CEP112	841	Q8N8E3
EEAQVAAVRQRVKAA	CARNS1	281	A5YM72
TRAKRARIADDEFDT	BRWD3	1721	Q6RI45
QTEKREVFERNIRAE	ANO4	131	Q32M45
EERDAFAERVRQRDK	DHX16	176	O60231
QEAERARFVVEKAEQ	PHB1	191	P35232
QRRLFDDTREAEKVL	RAB3GAP1	751	Q15042
QTVRFRVVSVDENFR	PZP	141	P20742
KERTRAARVDNFVIA	RIC1	1096	Q4ADV7
SQFEAQARKRECVRV	CPSF7	166	Q8N684
EARRRQSEEDEFRVK	PALM2	66	Q8IXS6
TFKQRRTFEQRVEDV	MAP1LC3B	6	Q9GZQ8
NSAFVERVRKRGFEV	HSP90AB1	496	P08238
RAAKVAEQQERERAA	PBRM1	1431	Q86U86
AENITVTKDFRRVEN	IRAK1BP1	106	Q5VVH5
EEAERVRQEREKHFQ	MAP7	576	Q14244
GDETRQRVKFTDDRV	LUC7L	21	Q9NQ29
EDIFSEVVGRKRQRS	DDX54	646	Q8TDD1
AARARVEKQRAEAAR	MYH7B	1176	A7E2Y1
SEENVREVFARARAA	PEX6	781	Q13608
GVSREVFDFSQRRKE	NFE2L2	31	Q16236
EVREAAQKRRAAEDA	EVPL	1336	Q92817
VFEVEVRRVKFARDS	FKBP15	281	Q5T1M5
RNFVKEAEEISSNRR	COG8	126	Q96MW5
AFQERDKIVAERDSI	DLG5	526	Q8TDM6
KTDEFNRTVFRTDRN	KIAA0408	441	Q6ZU52
RAVVFRDIEDSKQAQ	LRBA	1516	P50851
NEDIAAFAKQVRSER	MEIS3	106	Q99687
REATDKIREANRLFA	LAMA2	1791	P24043
AQERFSAEQEQRRRD	OTUD7A	661	Q8TE49
RVDSFNEEVRKQRVS	ITGB5	226	P18084
ERQVIDAERQAEKAF	PLEKHH2	46	Q8IVE3
AVNRVSAIRFVEDEK	LRRC1	451	Q9BTT6
RVTDERFVQKAARES	PPM1E	311	Q8WY54
DFKAVITRRQREAET	GLYATL3	51	Q5SZD4
AFSQSVQKIREEERR	ABCC5	376	O15440
REENVRRIAEVAKLF	PAPSS1	106	O43252
ELREADRQKEQTFRE	ILVBL	421	A1L0T0
SEIRQTRKFRDAEQE	CC2D2A	486	Q9P2K1
FVQKLREAQRERDDS	CROCC2	1371	H7BZ55
LKARRNRTAFEEVEE	DHX57	761	Q6P158
DKAAFEREARQRVQS	CCDC166	186	P0CW27
EKRRRKSVEDRFDQQ	DSP	1121	P15924
DEVVKQNVAAFERRA	COQ10A	211	Q96MF6
RADEDVEAAQRKLRQ	DEF6	521	Q9H4E7
KRQNKEEDVTRESRF	GLRA2	356	P23416
KRTVHEFINDQRDRF	CCDC38	106	Q502W7
EAASKAVTQRFREDA	KHDC3L	196	Q587J8
VEAARKAIRAAQVER	CENATAC	41	Q86UT8
QEAERFSREFVQRGK	EVC	431	P57679
DVSEFNQKVEDLDRR	DNAH9	511	Q9NYC9
VRLEEAFEFVKQRRS	DUSP4	301	Q13115
DQERFLSDLRRDVQK	SEC24C	731	P53992
SQRRFREAEDIIQKA	SLC22A4	286	Q9H015
EKVFRAVRETQEREA	ARCN1	141	P48444
AQFEKLTRALEEERR	CTNND1	21	O60716
ERIQAKTREFRERQA	PARD3	1061	Q8TEW0
RVDVFTDQVEHEKQR	TRIM31	166	Q9BZY9
EERRVQDELARSRKF	TRIM32	191	Q13049
NTVFRQEEFEDVKRN	MAP3K21	571	Q5TCX8
AAEREKEFVARVRAS	STX7	111	O15400
EEQLFKRRNVATAEE	KPNA1	41	P52294
RAVNRADTAKEVSFD	ITIH3	66	Q06033
LRAVVFRDVDDSKQA	NBEA	1546	Q8NFP9
KAEQELRVAQTEFDR	SH3GLB2	216	Q9NR46
TFEALKARVRELERQ	RNF220	491	Q5VTB9
DKEFVIRRAATNRVL	RASGRF1	941	Q13972
VERFNDDFIETRRKA	SNX7	106	Q9UNH6
AVKSVAEDFERRQAV	B3GNT9	121	Q6UX72
RRDLEKSTAEFQDVR	AKAP3	46	O75969
SERRFFEEEQERKLQ	TRAK1	511	Q9UPV9
VEKSRRFQAADRSEL	TMEM237	181	Q96Q45
SFRESVDAQEEIRKV	XIRP2	3076	A4UGR9
QKRVFDTVRIANDTR	TRAK2	401	O60296
TFKQRRTFEQRVEDV	MAP1LC3B2	6	A6NCE7
EANVREIFDKARQAA	VCP	556	P55072
VKRQFVEFTIREAVR	SAGE2P	566	A6NJ88
IKDREFETDSRRFLN	SYCP2L	266	Q5T4T6
REARDNAVAEKERAV	PIBF1	411	Q8WXW3
EKRRELEEETNAFNR	SEPTIN8	386	Q92599
RKEAEQEAARRAQAE	PLEC	2276	Q15149
VRDIFAQQRESKETA	ARHGAP18	171	Q8N392
NVIADHRDFKRDRET	YLPM1	1701	P49750
EVAEQRFQADRERTV	ZNF862	911	O60290
VFQRKFVNEVRRCEE	ATP6V0A1	46	Q93050
RKRRSEESRQEIEEF	ZUP1	246	Q96AP4
RARFEVADEDKQSRL	TMEM134	41	Q9H6X4
REEEERRKEATAHFQ	TXLNG	231	Q9NUQ3
RAEEQFATQEKSRRE	TCHH	1846	Q07283
VFDDKTRLVDRVRLN	WWC3	221	Q9ULE0
EQARAAGAREKERQE	MUC12	136	Q9UKN1