Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	PDZ	MAGI1 PCLO MAGI3 ARHGEF11 MAST4	1.43e-03	151	102	5	PS50106
Domain	PDZ	MAGI1 PCLO MAGI3 ARHGEF11 MAST4	1.48e-03	152	102	5	IPR001478
Domain	DUF4599	SPATA31D4 SPATA31D3	1.88e-03	12	102	2	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D3	1.88e-03	12	102	2	IPR027970
Domain	WW	MAGI1 MAGI3 SETD2	2.15e-03	47	102	3	PF00397
Domain	OTU	OTUD5 OTUD4	2.22e-03	13	102	2	PF02338
Domain	WW	MAGI1 MAGI3 SETD2	2.29e-03	48	102	3	SM00456
Domain	Gelsolin	SEC24A SVIL	2.57e-03	14	102	2	PF00626
Domain	Gelsolin-like_dom	SEC24A SVIL	2.57e-03	14	102	2	IPR007123
Domain	WW_DOMAIN_2	MAGI1 MAGI3 SETD2	2.72e-03	51	102	3	PS50020
Domain	WW_DOMAIN_1	MAGI1 MAGI3 SETD2	2.72e-03	51	102	3	PS01159
Domain	WW_dom	MAGI1 MAGI3 SETD2	2.88e-03	52	102	3	IPR001202
Domain	OTU	OTUD5 OTUD4	2.96e-03	15	102	2	PS50802
Domain	OTU_dom	OTUD5 OTUD4	2.96e-03	15	102	2	IPR003323
Domain	Guanylate_kinase_CS	MAGI1 MAGI3	3.37e-03	16	102	2	IPR020590
Domain	PH	PLEKHA6 ARHGEF11 PRKD3 IPCEF1 ITSN2 PSD4	4.21e-03	278	102	6	SM00233
Domain	PH_DOMAIN	PLEKHA6 ARHGEF11 PRKD3 IPCEF1 ITSN2 PSD4	4.29e-03	279	102	6	PS50003
Domain	PH_domain	PLEKHA6 ARHGEF11 PRKD3 IPCEF1 ITSN2 PSD4	4.36e-03	280	102	6	IPR001849
Domain	GUANYLATE_KINASE_2	MAGI1 MAGI3	6.93e-03	23	102	2	PS50052
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	GARIN5B CCDC50 KMT2E SPATA31D4 SPATA31D3 STARD9 MCM9 SCAPER GOLGA5	5.12e-08	233	108	9	37704626
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	MAP1A DSG1 RBBP6 KRBA1 SNW1 FAM193A SVIL CEP170B	1.18e-07	184	108	8	32908313
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TANC2 PRUNE2 CILK1 MAGI3 PLEKHA6 HIVEP3 SETD2 KRBA1 NUP210 SCAPER RIC1	4.16e-07	493	108	11	15368895
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 MAGI1 SEC24A MAGI3 MDM4 PRAG1 TRIP12 VIRMA MAST4 STARD9 SVIL TANC1 AKAP1 CEP170B	4.75e-07	861	108	14	36931259
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 MAP1A RBBP6 KMT2E MDM4 TRIP12 ZNF469 FAM193A IPCEF1 RIC1	9.91e-07	430	108	10	35044719
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	RBBP6 MIB2 TRIP12 RNF41	1.70e-06	28	108	4	35474067
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 TES MAP1A RBBP6 BTBD18 CUL9 BUD13 ZC3H3 SETD2 ZNF469 SCAPER ZFHX3 TANC1 CEP170B LRRC41	1.93e-06	1116	108	15	31753913
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CUL9 MAGI3 ARHGEF11 TRIP12 ITSN2 SCAPER	3.40e-06	130	108	6	12421765
Pubmed	Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.	CCDC50 PLEKHA6 PRAG1 ITSN2 MARVELD2	3.82e-06	75	108	5	15951569
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	STON1 MAP1A ZDBF2 FAM193A MAST4 TANC1 CEP170B	4.27e-06	209	108	7	36779422
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KDM3A OTUD5 RBBP6 TATDN2 BUD13 TRIP12 VIRMA SETD2 SVIL EIF2B5 OTUD4 AKAP1	5.37e-06	774	108	12	15302935
Pubmed	MAGI-1: a widely expressed, alternatively spliced tight junction protein.	MAGI1 MAGI3	9.55e-06	2	108	2	11969287
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	9.55e-06	2	108	2	31400758
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	9.55e-06	2	108	2	37450367
Pubmed	MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis.	MAGI1 MAGI3	9.55e-06	2	108	2	33712709
Pubmed	Regulation of dendritic spines, spatial memory, and embryonic development by the TANC family of PSD-95-interacting proteins.	TANC2 TANC1	9.55e-06	2	108	2	21068316
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	MAGI1 TES MAGI3 PLEKHA6 SVIL NECTIN4 TANC1 MARVELD2 GOLGA5 IL6ST	1.10e-05	565	108	10	25468996
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TES SEC24A CILK1 MAGI3 CCDC50 ARHGEF11 MAST4 SVIL ITSN2 TANC1 GOLGA5 CEP170B	1.42e-05	853	108	12	28718761
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RBBP6 CWC27 GON4L BUD13 CCDC50 SIX4 ARHGEF11 VIRMA AHDC1 SETD2 ITSN2 OTUD4 ZFHX3 TANC1 AKAP1 CEP170B	1.55e-05	1497	108	16	31527615
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TANC2 GON4L MAGI3 ZDBF2 HIVEP3	1.64e-05	101	108	5	10997877
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	TANC2 KDM3A PRPF8 PRAG1 VIRMA SNW1 STARD9 SVIL	1.78e-05	361	108	8	30344098
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RBBP6 BUD13 PRPF8 TRIP12 VIRMA SNW1 MCM9 EIF2B5 SCAPER SGO2 AKAP1	2.52e-05	759	108	11	35915203
Pubmed	Tanc1/2 TPR domain interacts with Myo18a C-terminus and undergoes liquid-liquid phase separation.	TANC2 TANC1	2.86e-05	3	108	2	38092135
Pubmed	Interaction of PDZRhoGEF with microtubule-associated protein 1 light chains: link between microtubules, actin cytoskeleton, and neuronal polarity.	MAP1A ARHGEF11	2.86e-05	3	108	2	16478718
Pubmed	Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.	CSF1 IL6ST	2.86e-05	3	108	2	14749363
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TES MAP1A DSG1 RBBP6 CCDC50 PRPF8 SETD2 SNW1 FAM193A R3HCC1L GOLGA5 AKAP1	3.45e-05	934	108	12	33916271
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TMEM94 GON4L CUL9 VIRMA STARD9 ITSN2 OTUD4 CEP170B	4.17e-05	407	108	8	12693553
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	MAGI1 MAGI3 EEF2K TANC1 CDC25A	5.14e-05	128	108	5	25332235
Pubmed	PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA.	MDM4 PRPF8	5.71e-05	4	108	2	34144037
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MAP1A OTUD5 RBBP6 CUL9 ZDBF2 MDM4 SETD2 TANC1 CEP170B	9.42e-05	588	108	9	38580884
Pubmed	FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.	FBXW10B FBXW10	9.50e-05	5	108	2	37277019
Pubmed	Elevated expression of the colony-stimulating factor 1 (CSF1) induces prostatic intraepithelial neoplasia dependent of epithelial-Gp130.	CSF1 IL6ST	9.50e-05	5	108	2	34999736
Pubmed	Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development.	MAGI1 MAGI3	1.42e-04	6	108	2	15509766
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	FBXW10 RBBP6 MIB2 TRIP12	1.47e-04	85	108	4	19028597
Pubmed	Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.	MAGI1 MAGI3 ARHGEF11	1.62e-04	34	108	3	30726710
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 SZT2 TMEM94 CUL9 MIB2 ARHGEF11 PRAG1 AHDC1 HIVEP3 TANC1 CEP170B RIC1	1.69e-04	1105	108	12	35748872
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	TES SEC24A FAM193A SVIL TANC1 GOLGA5	1.77e-04	263	108	6	34702444
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	TANC2 SEC24A BUD13 AHDC1 OTUD4 TANC1 SPINDOC	1.84e-04	378	108	7	34315543
Pubmed	A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin.	GYS1 EIF2B5	1.99e-04	7	108	2	10481074
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PRUNE2 MAGI1 CILK1 MAGI3 MDM4 AHDC1 HIVEP3 NUP210 ZFHX3 TANC1 NRG3 CEP170B RIC1 LRRC41	2.12e-04	1489	108	14	28611215
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	ZDBF2 TRIP12 SNW1 OTUD4 SPINDOC STAG3	2.13e-04	272	108	6	31010829
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	SZT2 OTUD5 CCDC50 ZDBF2 VIRMA ZBTB49 SETD2 SNW1 FAM193A MCM9 SCAPER CDC25A LRRC41	2.45e-04	1327	108	13	32694731
Pubmed	Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.	BUD13 SVIL ZFHX3	2.45e-04	39	108	3	19010793
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	ELOA2 RBBP6 ZC3H3 SNW1 SCAPER SPINDOC	2.53e-04	281	108	6	24163370
Pubmed	Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.	MAGI1 MAGI3	2.64e-04	8	108	2	16316992
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	KDM3A DSG1 OTUD5 MAGI3 PRPF8 TRIP12 PRKD3 GYS1 OTUD4 CDC25A AKAP1	2.99e-04	1005	108	11	19615732
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	TES OTUD5 CWC27 SEC24A CCDC50 PRKD3 SNW1 NUP210 ITSN2 GOLGA5 AKAP1	3.04e-04	1007	108	11	34597346
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	RBBP6 TRIP12 SNW1 ZFHX3	3.07e-04	103	108	4	32744500
Pubmed	Schizophrenia and vitamin D related genes could have been subject to latitude-driven adaptation.	MAGI1 INPP4B	3.39e-04	9	108	2	21070662
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	MAGI1 CACNA1I NRG3 CEP170B IL6ST	4.03e-04	199	108	5	23382691
Pubmed	Human ALKBH4 interacts with proteins associated with transcription.	TES ZFHX3	4.23e-04	10	108	2	23145062
Pubmed	Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions.	MAGI1 MAGI3	4.23e-04	10	108	2	19071123
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TES TMEM94 CCDC50 ZDBF2 SETD2 FAM193A TANC1 GOLGA5 AKAP1	4.78e-04	733	108	9	34672954
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	PCLO MIB2 PRKD3 FAM193A OTUD4 RNF41 AKAP1	6.14e-04	462	108	7	31138677
Pubmed	p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.	DGKG CCDC50	6.18e-04	12	108	2	9774969
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ACADVL PRPF8 DNAJB13 SNW1 FAM193A R3HCC1L NUP210 EEF2K TANC1 MARVELD2 GOLGA5 AKAP1 LRRC41	7.16e-04	1487	108	13	33957083
Pubmed	Role of SAP97 protein in the regulation of corticotropin-releasing factor receptor 1 endocytosis and extracellular signal-regulated kinase 1/2 signaling.	MAGI1 MAGI3	7.29e-04	13	108	2	23576434
Pubmed	cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner.	ACADVL EEF2K	7.29e-04	13	108	2	18337751
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	TES SEC24A CCDC50 PRPF8 ARHGEF11 NCKAP1L	7.36e-04	344	108	6	30333137
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	KDM3A BUD13 PRPF8 SNW1	7.40e-04	130	108	4	35545047
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM3A KMT2E SETD2	7.54e-04	57	108	3	18022353
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	TANC2 MAP1A PCLO CCDC92 PLEKHA6 CEP170B	7.70e-04	347	108	6	17114649
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	OTUD5 CCDC50 MIB2 CCDC92 TRIP12 ITSN2 OTUD4	7.78e-04	481	108	7	28190767
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	TANC2 MAP1A PCLO PLEKHA6 CEP170B	7.92e-04	231	108	5	16452087
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	ITSN2 OTUD4 EEF2K GOLGA5	8.05e-04	133	108	4	15144186
Pubmed	A human MAP kinase interactome.	MAGI1 MAP1A RBBP6 CCDC92 PLEKHA6 ARHGEF11 ITSN2	8.26e-04	486	108	7	20936779
Pubmed	SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.	TANC2 HEMGN MIB2 PRPF8 SVIL OTUD4	8.41e-04	353	108	6	27545878
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TANC2 ELOA2 ZDBF2 VIRMA GYS1 ITSN2 OTUD4 LRRC41	8.66e-04	638	108	8	31182584
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	LINC00322 RBBP6 CWC27 BUD13 MIB2 TRIP12	9.44e-04	361	108	6	26167880
Pubmed	Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1.	GCM2 SIX4	9.77e-04	15	108	2	16530750
Pubmed	Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.	MAGI1 MAGI3	9.77e-04	15	108	2	23782696
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	CCDC91 RBBP6 CWC27 CUL9 MAGI3 MAPK15 CSF1 NRG3 NCKAP1L	1.00e-03	814	108	9	23251661
Pubmed	A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.	MAP1A STARD9	1.11e-03	16	108	2	7633422
Pubmed	Structure of the human activated spliceosome in three conformational states.	CWC27 BUD13	1.11e-03	16	108	2	29360106
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	RBBP6 TRIP12 SETD2 NUP210 EEF2K	1.13e-03	250	108	5	33536335
Pubmed	RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis.	RBBP6 TRIP12	1.26e-03	17	108	2	37080995
Pubmed	Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.	ARHGEF11 ITSN2	1.42e-03	18	108	2	12799088
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	MAP1A PRPF8 SNW1 TANC1	1.45e-03	156	108	4	32850835
Pubmed	The protein interaction landscape of the human CMGC kinase group.	STON1 DSG1 RBBP6 TMEM94 CILK1 PRPF8 SETD2 MAPK15	1.49e-03	695	108	8	23602568
Pubmed	OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.	OTUD5 OTUD4	1.58e-03	19	108	2	23827681
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	SEC24A SIX4 PPEF1 SVIL NUP210 OTUD4 TANC1 MARVELD2 GOLGA5 CDC25A	1.61e-03	1049	108	10	27880917
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TANC2 MAP1A PCLO PLEKHA6 ARHGEF11 VIRMA SVIL ITSN2 SCAPER OTUD4 TANC1 CEP170B	1.64e-03	1431	108	12	37142655
Pubmed	An investigation into the human serum "interactome".	GARIN5B DGKG SGO2 CACNA1I	1.67e-03	162	108	4	15174051
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MAP1A DSG1 CWC27 PRPF8 TRIP12 SNW1 FAM193A OTUD4	1.93e-03	724	108	8	36232890
Pubmed	Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing.	PRPF8 SNW1	1.93e-03	21	108	2	12840015
Pubmed	Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.	INPP4B IL6ST	1.93e-03	21	108	2	24407287
Pubmed	A neurogenomics approach to gene expression analysis in the developing brain.	CILK1 TRIP12 SCAPER ZFHX3	1.99e-03	170	108	4	15582152
Pubmed	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.	CWC27 PRPF8 SNW1	2.01e-03	80	108	3	11991638
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	MAGI1 TMEM94 PLEKHA6 TANC1 GOLGA5 IL6ST PSD4	2.03e-03	569	108	7	30639242
Pubmed	The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.	PRAG1 ITSN2 NCKAP1L	2.08e-03	81	108	3	20697350
Pubmed	Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis.	SGO2 STAG3	2.12e-03	22	108	2	21690297
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	STON1 BTBD18 CILK1 AHDC1 ZBTB49 MAPK15 MCM9 MARVELD2 PSD4	2.23e-03	915	108	9	32393512
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	TANC2 MAGI1 DSG1 MAGI3 CCDC50 ARHGEF11 VIRMA ITSN2 AKAP1	2.25e-03	916	108	9	32203420
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ZDBF2 SIX4 PRPF8 SNW1 OTUD4 ZFHX3 LRRC41	2.33e-03	583	108	7	29844126
Pubmed	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	CILK1 KMT2E SNW1 SVIL	2.45e-03	180	108	4	24104479
Pubmed	A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.	CUL9 PRPF8	2.52e-03	24	108	2	33705438
Pubmed	A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels.	SERPINE3 BUD13	2.52e-03	24	108	2	25240745
Pubmed	Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.	MAGI1 MAGI3	2.74e-03	25	108	2	23873930
Pubmed	Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.	ACADVL PCLO SNW1	2.81e-03	90	108	3	31280863
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBBP6 BUD13 CCDC50 ZDBF2 PRPF8 TRIP12 SETD2 SNW1 SGO2	2.95e-03	954	108	9	36373674
Interaction	SERINC5 interactions	RBBP6 MIB2 TRIP12 VIRMA RNF41	5.71e-07	32	103	5	int:SERINC5
Interaction	GSK3A interactions	STON1 MAP1A ZDBF2 ARHGEF11 AHDC1 PRKD3 KRBA1 SNW1 FAM193A MAST4 EIF2B5 TANC1 CEP170B	7.03e-07	464	103	13	int:GSK3A
Interaction	SNRNP40 interactions	KDM3A DSG1 RBBP6 GON4L CUL9 BUD13 ZDBF2 PRPF8 VIRMA AHDC1 SETD2 SNW1 ITSN2 ZFHX3	4.44e-06	637	103	14	int:SNRNP40
Interaction	NUP43 interactions	KDM3A DSG1 SZT2 RBBP6 GON4L BUD13 ZDBF2 TRIP12 VIRMA AHDC1 SETD2 EIF2B5 ZFHX3	1.79e-05	625	103	13	int:NUP43
Interaction	VASP interactions	MAGI1 TES MAP1A SEC24A VIRMA SNW1 R3HCC1L SVIL CEP170B	2.00e-05	294	103	9	int:VASP
Interaction	TLE3 interactions	KDM3A RBBP6 SEC24A SIX4 VIRMA AHDC1 SETD2 FAM193A OTUD4 ZFHX3	2.29e-05	376	103	10	int:TLE3
GeneFamily	PDZ domain containing	MAGI1 PCLO MAGI3 ARHGEF11 MAST4	1.26e-04	152	58	5	1220
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PCLO INPP4B ITSN2	2.07e-04	36	58	3	823
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10	5.46e-04	11	58	2	559
GeneFamily	OTU domain containing	OTUD5 OTUD4	1.33e-03	17	58	2	669
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MAGI1 MAGI3	3.13e-03	26	58	2	904
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHA6 PRKD3 IPCEF1 PSD4	4.30e-03	206	58	4	682
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2E SETD2	5.31e-03	34	58	2	487
GeneFamily	EF-hand domain containing	CAPN9 DGKG PPEF1 ITSN2	5.33e-03	219	58	4	863
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_only / Treatment groups by lineage, cell group, cell type	MAP1A CUL9 CCDC50 PRAG1 GRHL1 EEF2K PSD4	5.51e-07	198	108	7	d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MAGI3 GRHL1 MAST4 NECTIN4 TANC1	3.71e-06	170	108	6	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MAGI3 INPP4B GRHL1 MAST4 NECTIN4	7.23e-06	191	108	6	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	MAGI1 DGKG INPP4B MAST4 SVIL TANC1	7.45e-06	192	108	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	MAGI1 MAGI3 INPP4B GRHL1 MAST4 NECTIN4	7.67e-06	193	108	6	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MAGI1 DGKG PRAG1 FNDC1 ZFHX3 AKAP1	7.67e-06	193	108	6	000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MAGI3 INPP4B GRHL1 MAST4 NECTIN4	8.14e-06	195	108	6	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	MDM4 INPP4B IPCEF1 SCAPER IL6ST	3.36e-05	151	108	5	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 MAGI3 GRHL1 MAST4 AKAP1	4.70e-05	162	108	5	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	CAPN9 MAGI1 MAGI3 MAST4 NECTIN4	4.84e-05	163	108	5	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright\|ICU-NoSEP / Disease, Lineage and Cell Type	RBBP6 HEMGN ZNF469 KRBA1 UBAP1L	5.43e-05	167	108	5	f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	CAPN9 MAGI3 SIX4 GRHL1 MAST4	5.91e-05	170	108	5	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRAG1 INPP4B IPCEF1 STAG3 IL6ST	7.15e-05	177	108	5	64b8f665fdaf975558af2ad7d9b54d206de8350c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MAGI3 GRHL1 MAST4 NECTIN4	7.35e-05	178	108	5	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TANC2 GRHL1 IPCEF1 NECTIN4 TANC1	7.54e-05	179	108	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MAGI3 INPP4B GRHL1 MAST4	7.74e-05	180	108	5	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	PRUNE2 DGKG INPP4B SVIL ZFHX3	7.74e-05	180	108	5	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	TATDN2 MAGI3 SETD2 R3HCC1L IPCEF1	7.95e-05	181	108	5	b193f3606554adc55c5906219d114288bb1f978a
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	MAGI1 MAGI3 GRHL1 MAST4 SVIL	7.95e-05	181	108	5	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MAGI3 INPP4B GRHL1 NECTIN4	8.16e-05	182	108	5	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 TES STON1 DGKG SVIL	8.16e-05	182	108	5	7b86703559438e2d5ef3dad963ee0d772513f313
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	INPP4B IPCEF1 SVIL TANC1 IL6ST	8.16e-05	182	108	5	b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell	facs-Skin-Telogen-3m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRHL1 NECTIN4 EEF2K TANC1 MARVELD2	8.37e-05	183	108	5	ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PRAG1 INPP4B IPCEF1 SVIL NRG3	8.59e-05	184	108	5	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	TANC2 GON4L CCDC92 R3HCC1L SGO2	8.59e-05	184	108	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	MAGI1 DGKG INPP4B MAST4 SVIL	8.59e-05	184	108	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MAGI3 GRHL1 MAST4 NECTIN4	8.59e-05	184	108	5	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CAPN9 MAGI1 TES MAGI3 NRG3	8.81e-05	185	108	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	CAPN9 MAGI1 MAGI3 GRHL1 MAST4	8.81e-05	185	108	5	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 ZBTB49 CSF1 TANC1 IL6ST	8.81e-05	185	108	5	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	MAGI1 MAGI3 MAST4 NECTIN4 TANC1	9.04e-05	186	108	5	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 PCLO DGKG IPCEF1 NECTIN4	9.27e-05	187	108	5	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	CAPN9 MAGI1 MAGI3 TANC1 NRG3	9.27e-05	187	108	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PRUNE2 MAGI1 INPP4B SVIL TANC1	9.50e-05	188	108	5	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MAGI1 DGKG MAST4 SVIL TANC1	9.74e-05	189	108	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	T_cells-Effector_memory_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MAGI3 INPP4B CSF1 CACNA1I IL6ST	9.99e-05	190	108	5	13dc3a0aaa554f63eabac37726bd1f11b66fb3dd
ToppCell	COPD-Epithelial-Club\|COPD / Disease state, Lineage and Cell class	MAGI1 MAGI3 MAST4 NECTIN4 TANC1	1.02e-04	191	108	5	c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 MAST4 IPCEF1 SVIL SCAPER	1.05e-04	192	108	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 MAGI1 PCLO PLEKHA6 MAST4	1.07e-04	193	108	5	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	C12orf71 FBXW10 ZNF469 CSF1 NCKAP1L	1.10e-04	194	108	5	4f28841c7f37884fc34c6689cd6976c6559d23f1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 MAGI1 PRAG1 IPCEF1 SVIL	1.10e-04	194	108	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 MAGI1 PLEKHA6 MAST4 IPCEF1	1.10e-04	194	108	5	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SIX4 INPP4B GRHL1 MAST4 NECTIN4	1.10e-04	194	108	5	0cd4363627acd419e00d6d32f6dce10430aa6487
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PRUNE2 MAGI1 MAST4 SVIL TANC1	1.10e-04	194	108	5	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SIX4 INPP4B GRHL1 MAST4 NECTIN4	1.10e-04	194	108	5	a58841b34efe673671a9a059238e044a7254b279
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid-Microglia\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	C12orf71 FBXW10 ZNF469 CSF1 NCKAP1L	1.10e-04	194	108	5	459e836bcdb6742333684ac23d960efa5e99702f
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	MAP1A PPEF1 FNDC1 ZNF469 HRC	1.10e-04	194	108	5	55b97095a7a17a312c616703d291738a0f806339
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CAPN9 MAGI1 TES MAGI3 NRG3	1.13e-04	195	108	5	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	COVID-19-Lymphoid-Tregs\|Lymphoid / Condition, Lineage and Cell class	MAGI1 CUL9 MAST4 IPCEF1 IL6ST	1.13e-04	195	108	5	9ad844d9d5aac39d133ae8ab9c4839300f08064c
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	MAGI1 DGKG INPP4B MAST4 SVIL	1.13e-04	195	108	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	Fibroblasts-Pericytes\|Fibroblasts / lung cells shred on cell class, cell subclass, sample id	PRUNE2 DGKG INPP4B SVIL ZFHX3	1.13e-04	195	108	5	c2ebc0b33bda9b35b9ef26d69e5d2c6acfdb6ff1
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 MAGI1 MAGI3 HIVEP3 SCAPER	1.16e-04	196	108	5	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	DGKG PRAG1 MAST4 TANC1 NRG3	1.16e-04	196	108	5	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 MAGI1 MAGI3 SCAPER TANC1	1.21e-04	198	108	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 MAGI3 INPP4B GRHL1 MAST4	1.21e-04	198	108	5	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TANC2 RBBP6 PRAG1 SVIL NCKAP1L	1.24e-04	199	108	5	fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	MAGI1 RBBP6 ZBTB49 MAST4 SGO2	1.27e-04	200	108	5	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2E MDM4 TRIP12 SETD2 ITSN2	1.27e-04	200	108	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	MAGI1 RBBP6 ZBTB49 MAST4 SGO2	1.27e-04	200	108	5	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-NoSEP / Disease, condition lineage and cell class	RBBP6 HEMGN ZNF469 KRBA1 UBAP1L	1.27e-04	200	108	5	c2df917900872453ea17a39928e39d071a6d3339
Drug	Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A	TANC2 PLEKHA6 MAST4 SVIL NUP210 SCAPER CDC25A AKAP1	1.55e-06	177	104	8	4652_DN
Disease	Neurodevelopmental Disorders	TANC2 KMT2E TRIP12 HIVEP3 SETD2	2.01e-05	93	104	5	C1535926
Disease	internal carotid intimal medial thickness	MAST4 NRG3	1.22e-04	5	104	2	EFO_0005053
Disease	cervical cancer (is_implicated_in)	KDM3A KMT2E CDC25A	1.61e-04	30	104	3	DOID:4362 (is_implicated_in)
Disease	triple-negative breast cancer	CCDC91 MDM4	5.44e-04	10	104	2	EFO_0005537
Disease	developmental disorder of mental health (implicated_via_orthology)	TANC2 TANC1 NCKAP1L	6.97e-04	49	104	3	DOID:0060037 (implicated_via_orthology)
Disease	breast carcinoma (is_marker_for)	SNW1 ZFHX3 CDC25A	1.66e-03	66	104	3	DOID:3459 (is_marker_for)
Disease	Tourette syndrome, schizophrenia	CCDC92 CACNA1I	1.81e-03	18	104	2	EFO_0004895, MONDO_0005090
Disease	mean arterial pressure	C12orf71 STON1 SZT2 TRIP12 PRKD3 HIVEP3 ZFHX3	1.97e-03	499	104	7	EFO_0006340
Disease	platelet crit	STON1 MAP1A HEMGN PLEKHA6 ARHGEF11 KRBA1 CSF1 MAST4 SVIL OTUD4	1.98e-03	952	104	10	EFO_0007985
Disease	nasopharyngeal neoplasm	PCLO R3HCC1L ZFHX3 NRG3	2.04e-03	151	104	4	EFO_0004252
Disease	heart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer	GRHL1 ZFHX3	2.24e-03	20	104	2	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Disease	short-term memory	ZDBF2 MCM9 ITSN2	3.19e-03	83	104	3	EFO_0004335
Disease	coronary artery disease	STON1 HEMGN MAGI3 BUD13 CCDC92 AHDC1 FNDC1 R3HCC1L MAST4 NUP210 CDC25A	3.27e-03	1194	104	11	EFO_0001645

Protein segments in the cluster

Peptide	Gene	Start	Entry
HSPSEKSHLSPLERS	C2orf16	1846	Q68DN1
LSSPRHKQSPGHQDS	BUD13	356	Q9BRD0
PTKDSKPNISAHHIS	AKAP1	446	Q92667
RHHSKDPSRDPALTV	CCDC187	306	A0A096LP49
SSHDLLKDDPHLSSV	CWC27	231	Q6UX04
ESDEPHHSKNERPAR	CCDC50	251	Q8IVM0
QHTSLPLSKAPENEH	FBXW10	201	Q5XX13
KSPSHHRQPSDASET	ARHGEF11	26	O15085
EERATPHAKSERPSH	AHDC1	181	Q5TGY3
PGDDRHSTKSDLPVH	CEP170B	331	Q9Y4F5
TSDIEIPEAKHDHRP	C22orf42	121	Q6IC83
SKEDHRHSAPAAPRN	FAM193A	651	P78312
NDSTADELHVKHEPP	R3HCC1L	336	Q7Z5L2
DSIHGHSQLDKRPEP	OTUD4	516	Q01804
SSTHSEHKPSREKSP	RIC1	446	Q4ADV7
ENTPESHADHSSLKL	ITSN2	1366	Q9NZM3
QHTSLPLSKAPENEH	FBXW10B	201	O95170
EVPSPDRGSQSVKHH	NRG3	456	P56975
SHLSSARTKQPHDPL	NUP210	866	Q8TEM1
ALEEAPDSHQKRPQH	ELOA2	296	Q8IYF1
QKPELQPHRSHSEEA	KRBA1	421	A5PL33
THTPFHQSPVEEKSE	MAP1A	1006	P78559
KTENEVPSPASSHHS	MAGI1	931	Q96QZ7
SVSPKKPASQHSEEH	MAGI3	1221	Q5TCQ9
PTLPTSEHKCIHSRE	MDM4	156	O15151
HDPAEHESPRAAKNV	MAPK15	396	Q8TD08
HTPTPNDDGKSHELS	GOLGA5	211	Q8TBA6
SHDTVRTSVLPEHKD	INPP4B	121	O15327
KESSPSHPTRCHEDN	EIF2B5	186	Q13144
SENSQHLELHEPPKA	PCLO	4596	Q9Y6V0
TSVAKAPLHLHENPD	NCKAP1L	496	P55160
EPTALHKTLETPAHD	KMT2E	1031	Q8IZD2
HKTLETPAHDRAEPN	KMT2E	1036	Q8IZD2
PSEESHVHQEPSKRI	PRKD3	236	O94806
SRDSEDLQKTHSPRH	LMNTD2	321	Q8IXW0
TLKPSVHVHDNRPAS	DSG1	846	Q02413
KAPSHKTIQETPHSE	HEMGN	336	Q9BXL5
KSNSSPSRDRKPHDH	RBBP6	1531	Q7Z6E9
VSASHSPDHPVVKSE	BTBD18	431	B2RXH4
QKPRHETSDHPTEGA	DGKG	81	P49619
LSSNHDHLTVPDKPA	IPCEF1	281	Q8WWN9
QHESSPDISHFERSK	IL6ST	821	P40189
PEVEHPEPDHSKRNS	GRHL1	81	Q9NZI5
LQKHLEHAPSPSDVS	KDM3A	436	Q9Y4C1
NHTPQKTDHPSALLR	CSF1	381	P09603
HSEKSPPSTENKHEA	C16orf87	46	Q6PH81
HLSPSSPEIVLDRDH	CCDC91	41	Q7Z6B0
HSTIPSDTHTSREKP	LINC00322	16	Q6ZN03
SDTHTSREKPRFHKP	LINC00322	21	Q6ZN03
DRSGEQHSPAREKPH	CCDC92	271	Q53HC0
SSAAASVDHPLKPRH	FNDC1	31	Q4ZHG4
HKPPSAEHESLLSAE	CACNA1I	996	Q9P0X4
SKEPHELVGSSPHRE	GON4L	1886	Q3T8J9
SIVLHEKAPHSDSTP	AKNAD1	631	Q5T1N1
HPTLHDSERAVSADP	MARVELD2	31	Q8N4S9
REGSSPKHQDHTTDP	MAST4	1921	O15021
HHPLKSNEPSSAEIF	DNAJB13	31	P59910
SSNPHRASKLTDHNP	CUL9	1176	Q8IWT3
SPSSATPHSQKLDHL	EEF2K	396	O00418
PSLSRHSSPHQSEDE	GYS1	646	P13807
QAHPVPKDARITHSS	CAPN9	11	O14815
SHLSDCEHNPKRPVT	RNF41	101	Q9H4P4
ESHPKDSLHSCDHPL	SCAPER	326	Q9BY12
SPALKRSHSDSLDHD	CDC25A	116	P30304
RSSASSPEHPELHAE	OTUD5	456	Q96G74
IDHKSSTDNHEAPPT	MUCL3	106	Q3MIW9
DVNLPDAHSDTPLHS	MIB2	556	Q96AX9
PPTETNRDHDTDSKH	PPEF1	311	O14829
VSADKPDSVLTHHVP	MCM9	831	Q9NXL9
EVELPTASDPQHHRS	SZT2	1626	Q5T011
AHDQDPSKCHELSPR	TES	156	Q9UGI8
AATRAKPSAAEHPSH	TATDN2	206	Q93075
EIPSHSANVKDTHSP	PRUNE2	1251	Q8WUY3
DSSFTEVPRSPKHAH	SVIL	236	O95425
EVPRSPKHAHSSSLQ	SVIL	241	O95425
TDLKRELHPPATSHE	LRRC41	336	Q15345
PREEPNHRSSAKDIH	SEC24A	651	O95486
VHDHPRPESKSETEA	GCM2	156	O75603
KSHSSPSLHQDEAPT	PSD4	1016	Q8NDX1
SKGHEDLSPHPLSSS	SIX4	301	Q9UIU6
VPPRESHSHSDQSSK	SGO2	231	Q562F6
PETSPVLHLDHSADS	TANC1	26	Q9C0D5
IASDSPHASPKHVDA	TANC2	396	Q9HCD6
TAPKNHLLHDPETSS	SPATA31D4	776	Q6ZUB0
LEQHPHTLDLSPSEK	SPINDOC	111	Q9BUA3
LHSPRDHPDENKDVS	HRC	61	P23327
DDGTTDHRHLKPATP	STARD9	3391	Q9P2P6
SRSLSEGHPTAQHEK	ACADVL	586	P49748
SRTDHPSHLQEDKPS	CILK1	356	Q9UPZ9
RDHPVNATKSPHRSA	C12orf71	231	A8MTZ7
HRHSVKSQEPLPDDD	PRPF8	361	Q6P2Q9
AVRHSHEKPDSENVP	PLEKHA6	171	Q9Y2H5
TAPKNHLLHDPETSS	SPATA31D3	776	P0C874
PSRAHLPTKEASSLH	ZC3H3	511	Q8IXZ2
DRLPDKNSSLDHPHC	STON1	636	Q9Y6Q2
HRHSRKQSEPPANDL	STAG3	86	Q9UJ98
SGKVEPPHSSHEDLT	TMEM94	436	Q12767
SPDHPNHKSNESLLI	TEX54	66	A0A1B0GVG6
SEHPLSHKPEDTHTI	HIVEP3	346	Q5T1R4
SEPIEELHSRPHKSQ	ZDBF2	111	Q9HCK1
KDTPLSHIEPHLTAS	SERPINE3	266	A8MV23
RPSDSSRPKEHEHEG	SNW1	516	Q13573
RHHPVFSSSDPLEKA	PRAG1	871	Q86YV5
ESHPHGVKRSASPDD	SMAP	6	O00193
TSHTDVKSDPLGHPN	SETD2	1171	Q9BYW2
AHSAPRPFSDSLHKS	ZNF469	361	Q96JG9
LNPHKSHPDTAADLL	UBAP1L	251	F5GYI3
QNKTLDESHPHASPS	ZBTB49	166	Q6ZSB9
QHTESPSETNKPHSK	TRIP12	96	Q14669
DHLAEKTSSLPNHSE	VIRMA	571	Q69YN4
KTSSLPNHSEPDHDT	VIRMA	576	Q69YN4
AARNAKEHPSLLPHS	ZFHX3	3561	Q15911
EKKSHSDPRPDRTHT	GARIN5B	251	Q8N5Q1
LHSHHTDPRSQPEES	NECTIN4	401	Q96NY8