| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | inward rectifier potassium channel activity | 2.09e-14 | 28 | 64 | 8 | GO:0005242 | |
| GeneOntologyMolecularFunction | voltage-gated potassium channel activity | 1.23e-09 | 102 | 64 | 8 | GO:0005249 | |
| GeneOntologyMolecularFunction | potassium channel activity | 7.49e-09 | 128 | 64 | 8 | GO:0005267 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic cation channel activity | 1.52e-08 | 140 | 64 | 8 | GO:0099094 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic cation channel activity | 2.89e-08 | 152 | 64 | 8 | GO:0022843 | |
| GeneOntologyMolecularFunction | potassium ion transmembrane transporter activity | 6.01e-08 | 167 | 64 | 8 | GO:0015079 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity | 1.17e-07 | 182 | 64 | 8 | GO:0005244 | |
| GeneOntologyMolecularFunction | G-protein activated inward rectifier potassium channel activity | 1.25e-07 | 4 | 64 | 3 | GO:0015467 | |
| GeneOntologyMolecularFunction | voltage-gated channel activity | 1.27e-07 | 184 | 64 | 8 | GO:0022832 | |
| GeneOntologyMolecularFunction | histone binding | 1.62e-07 | 265 | 64 | 9 | GO:0042393 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic ion channel activity | 1.84e-07 | 193 | 64 | 8 | GO:0015276 | |
| GeneOntologyMolecularFunction | ligand-gated channel activity | 2.15e-07 | 197 | 64 | 8 | GO:0022834 | |
| GeneOntologyMolecularFunction | gated channel activity | 1.10e-05 | 334 | 64 | 8 | GO:0022836 | |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | 1.34e-05 | 343 | 64 | 8 | GO:0005261 | |
| GeneOntologyMolecularFunction | PDZ domain binding | 4.66e-05 | 123 | 64 | 5 | GO:0030165 | |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | 1.05e-04 | 459 | 64 | 8 | GO:0005216 | |
| GeneOntologyMolecularFunction | chromatin binding | 1.13e-04 | 739 | 64 | 10 | GO:0003682 | |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | 1.15e-04 | 465 | 64 | 8 | GO:0046873 | |
| GeneOntologyMolecularFunction | chromatin insulator sequence binding | 2.10e-04 | 7 | 64 | 2 | GO:0043035 | |
| GeneOntologyMolecularFunction | channel activity | 2.63e-04 | 525 | 64 | 8 | GO:0015267 | |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | 2.66e-04 | 526 | 64 | 8 | GO:0022803 | |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | 8.50e-04 | 627 | 64 | 8 | GO:0022890 | |
| GeneOntologyMolecularFunction | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | 1.03e-03 | 15 | 64 | 2 | GO:0086008 | |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | 1.23e-03 | 664 | 64 | 8 | GO:0008324 | |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | 2.81e-03 | 758 | 64 | 8 | GO:0015318 | |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | 3.70e-03 | 793 | 64 | 8 | GO:0015075 | |
| GeneOntologyMolecularFunction | transmembrane transporter activity | CNNM1 KCNJ2 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ12 KCNJ14 OSCP1 KCNJ18 | 4.10e-03 | 1180 | 64 | 10 | GO:0022857 |
| GeneOntologyMolecularFunction | protein phosphatase 1 binding | 5.62e-03 | 35 | 64 | 2 | GO:0008157 | |
| GeneOntologyMolecularFunction | transporter activity | CNNM1 KCNJ2 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ12 KCNJ14 OSCP1 KCNJ18 | 7.57e-03 | 1289 | 64 | 10 | GO:0005215 |
| GeneOntologyMolecularFunction | G-protein alpha-subunit binding | 8.39e-03 | 43 | 64 | 2 | GO:0001965 | |
| GeneOntologyBiologicalProcess | gonadal mesoderm development | 7.07e-17 | 9 | 64 | 7 | GO:0007506 | |
| GeneOntologyBiologicalProcess | potassium ion import across plasma membrane | 3.13e-12 | 51 | 64 | 8 | GO:1990573 | |
| GeneOntologyBiologicalProcess | nucleosome assembly | 3.99e-09 | 122 | 64 | 8 | GO:0006334 | |
| GeneOntologyBiologicalProcess | inorganic ion import across plasma membrane | 1.32e-08 | 142 | 64 | 8 | GO:0099587 | |
| GeneOntologyBiologicalProcess | inorganic cation import across plasma membrane | 1.32e-08 | 142 | 64 | 8 | GO:0098659 | |
| GeneOntologyBiologicalProcess | nucleosome organization | 1.32e-08 | 142 | 64 | 8 | GO:0034728 | |
| GeneOntologyBiologicalProcess | mesoderm development | 2.91e-08 | 157 | 64 | 8 | GO:0007498 | |
| GeneOntologyBiologicalProcess | gonad development | 2.81e-07 | 292 | 64 | 9 | GO:0008406 | |
| GeneOntologyBiologicalProcess | reproductive system development | 3.03e-07 | 388 | 64 | 10 | GO:0061458 | |
| GeneOntologyBiologicalProcess | development of primary sexual characteristics | 3.24e-07 | 297 | 64 | 9 | GO:0045137 | |
| GeneOntologyBiologicalProcess | import across plasma membrane | 5.47e-07 | 230 | 64 | 8 | GO:0098739 | |
| GeneOntologyBiologicalProcess | potassium ion transmembrane transport | 5.84e-07 | 232 | 64 | 8 | GO:0071805 | |
| GeneOntologyBiologicalProcess | protein-DNA complex assembly | 9.96e-07 | 249 | 64 | 8 | GO:0065004 | |
| GeneOntologyBiologicalProcess | sex differentiation | 1.34e-06 | 352 | 64 | 9 | GO:0007548 | |
| GeneOntologyBiologicalProcess | potassium ion transport | 1.93e-06 | 272 | 64 | 8 | GO:0006813 | |
| GeneOntologyBiologicalProcess | mesenchyme development | 2.11e-06 | 372 | 64 | 9 | GO:0060485 | |
| GeneOntologyBiologicalProcess | reproductive structure development | 2.67e-06 | 383 | 64 | 9 | GO:0048608 | |
| GeneOntologyBiologicalProcess | regulation of monoatomic ion transmembrane transport | 4.29e-05 | 417 | 64 | 8 | GO:0034765 | |
| GeneOntologyBiologicalProcess | spermatogenesis | 9.13e-05 | 744 | 64 | 10 | GO:0007283 | |
| GeneOntologyBiologicalProcess | male gamete generation | 1.11e-04 | 762 | 64 | 10 | GO:0048232 | |
| GeneOntologyBiologicalProcess | regulation of monoatomic ion transport | 3.99e-04 | 577 | 64 | 8 | GO:0043269 | |
| GeneOntologyBiologicalProcess | chromatin remodeling | 4.46e-04 | 741 | 64 | 9 | GO:0006338 | |
| GeneOntologyBiologicalProcess | regulation of transmembrane transport | 4.57e-04 | 589 | 64 | 8 | GO:0034762 | |
| GeneOntologyBiologicalProcess | mucociliary clearance | 7.23e-04 | 13 | 64 | 2 | GO:0120197 | |
| GeneOntologyBiologicalProcess | gamete generation | 8.34e-04 | 982 | 64 | 10 | GO:0007276 | |
| GeneOntologyBiologicalProcess | multicellular organismal reproductive process | TSPY4 TSPY3 TSPY10 PPP1R9B TSPY2 TSPY9 TSPY8 TSPY1 SPAG6 ZFX ZFY | 1.02e-03 | 1194 | 64 | 11 | GO:0048609 |
| GeneOntologyCellularComponent | voltage-gated potassium channel complex | 9.40e-06 | 91 | 65 | 5 | GO:0008076 | |
| GeneOntologyCellularComponent | potassium channel complex | 1.80e-05 | 104 | 65 | 5 | GO:0034705 | |
| GeneOntologyCellularComponent | monoatomic ion channel complex | 2.18e-05 | 378 | 65 | 8 | GO:0034702 | |
| GeneOntologyCellularComponent | transmembrane transporter complex | 3.30e-05 | 523 | 65 | 9 | GO:1902495 | |
| GeneOntologyCellularComponent | transporter complex | 4.88e-05 | 550 | 65 | 9 | GO:1990351 | |
| GeneOntologyCellularComponent | T-tubule | 1.07e-04 | 79 | 65 | 4 | GO:0030315 | |
| GeneOntologyCellularComponent | cation channel complex | 8.21e-04 | 235 | 65 | 5 | GO:0034703 | |
| GeneOntologyCellularComponent | dendrite | CNNM1 KCNJ2 KCNJ4 KCNJ6 KCNJ12 KCNJ14 CNTNAP4 PPP1R9B KCNJ18 | 1.29e-03 | 858 | 65 | 9 | GO:0030425 |
| GeneOntologyCellularComponent | dendritic tree | CNNM1 KCNJ2 KCNJ4 KCNJ6 KCNJ12 KCNJ14 CNTNAP4 PPP1R9B KCNJ18 | 1.31e-03 | 860 | 65 | 9 | GO:0097447 |
| GeneOntologyCellularComponent | membrane protein complex | COPZ1 KCNJ2 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ12 KCNJ14 C5 KCNJ18 NDUFAB1 ITGB4 | 2.02e-03 | 1498 | 65 | 12 | GO:0098796 |
| GeneOntologyCellularComponent | synaptic membrane | 2.17e-03 | 583 | 65 | 7 | GO:0097060 | |
| GeneOntologyCellularComponent | sarcolemma | 2.91e-03 | 190 | 65 | 4 | GO:0042383 | |
| HumanPheno | Episodic flaccid weakness | 8.83e-07 | 7 | 16 | 3 | HP:0003752 | |
| HumanPheno | Periodic hypokalemic paresis | 2.11e-06 | 9 | 16 | 3 | HP:0008153 | |
| HumanPheno | Periodic paralysis | 4.13e-06 | 11 | 16 | 3 | HP:0003768 | |
| HumanPheno | Bidirectional ventricular ectopy | 9.25e-06 | 2 | 16 | 2 | HP:0005147 | |
| HumanPheno | Muscle flaccidity | 1.13e-05 | 15 | 16 | 3 | HP:0010547 | |
| HumanPheno | Prolonged QT interval | 1.87e-05 | 54 | 16 | 4 | HP:0001657 | |
| HumanPheno | Polymorphic and polytopic ventricular extrasystoles | 2.77e-05 | 3 | 16 | 2 | HP:0006696 | |
| HumanPheno | Periodic hyperkalemic paralysis | 2.77e-05 | 3 | 16 | 2 | HP:0007215 | |
| HumanPheno | Ventricular fibrillation | 3.46e-05 | 63 | 16 | 4 | HP:0001663 | |
| HumanPheno | Abnormal QT interval | 3.68e-05 | 64 | 16 | 4 | HP:0031547 | |
| HumanPheno | Abnormal EKG | 4.34e-05 | 136 | 16 | 5 | HP:0003115 | |
| HumanPheno | Prominent U wave | 5.53e-05 | 4 | 16 | 2 | HP:0025072 | |
| HumanPheno | Aplasia of the bladder | 9.20e-05 | 5 | 16 | 2 | HP:0010477 | |
| HumanPheno | Abnormal U wave | 9.20e-05 | 5 | 16 | 2 | HP:0025070 | |
| HumanPheno | Abnormality of dental color | 1.43e-04 | 34 | 16 | 3 | HP:0011073 | |
| HumanPheno | Abnormal cardiological findings | 1.57e-04 | 178 | 16 | 5 | HP:0003114 | |
| HumanPheno | Abnormal cardiac test | 1.61e-04 | 179 | 16 | 5 | HP:0500015 | |
| HumanPheno | Abnormal test result | 1.70e-04 | 181 | 16 | 5 | HP:0500014 | |
| HumanPheno | Abnormal T-wave | 1.85e-04 | 37 | 16 | 3 | HP:0005135 | |
| HumanPheno | Intractable diarrhea | 2.56e-04 | 8 | 16 | 2 | HP:0002041 | |
| HumanPheno | Palpitations | 2.66e-04 | 106 | 16 | 4 | HP:0001962 | |
| HumanPheno | Cardiomyocyte hypertrophy | 3.29e-04 | 9 | 16 | 2 | HP:0031319 | |
| HumanPheno | Permanent atrial fibrillation | 3.29e-04 | 9 | 16 | 2 | HP:0004754 | |
| HumanPheno | Bilateral renal agenesis | 4.10e-04 | 10 | 16 | 2 | HP:0010958 | |
| HumanPheno | Impaired myocardial contractility | 4.10e-04 | 10 | 16 | 2 | HP:0006670 | |
| HumanPheno | Polymorphic ventricular tachycardia | 4.10e-04 | 10 | 16 | 2 | HP:0031677 | |
| HumanPheno | Abnormal atrioventricular conduction | 5.98e-04 | 131 | 16 | 4 | HP:0005150 | |
| HumanPheno | Atrioventricular nodal disease | 5.98e-04 | 131 | 16 | 4 | HP:0005142 | |
| HumanPheno | Heart block | 6.89e-04 | 136 | 16 | 4 | HP:0012722 | |
| HumanPheno | Ventricular septal hypertrophy | 7.07e-04 | 13 | 16 | 2 | HP:0005144 | |
| HumanPheno | Clinodactyly of the 5th toe | 7.07e-04 | 13 | 16 | 2 | HP:0001864 | |
| HumanPheno | Dental crowding | 8.55e-04 | 144 | 16 | 4 | HP:0000678 | |
| HumanPheno | Early young adult onset | 9.00e-04 | 63 | 16 | 3 | HP:0025708 | |
| HumanPheno | Abnormal cardiomyocyte morphology | 1.08e-03 | 16 | 16 | 2 | HP:0031331 | |
| HumanPheno | Aplasia/Hypoplasia of the bladder | 1.08e-03 | 16 | 16 | 2 | HP:0010476 | |
| HumanPheno | Deviation of the 5th toe | 1.08e-03 | 16 | 16 | 2 | HP:0010344 | |
| HumanPheno | Ventricular tachycardia | 1.17e-03 | 69 | 16 | 3 | HP:0004756 | |
| Domain | K_chnl_inward-rec_Kir_cyto | 1.01e-16 | 16 | 61 | 8 | IPR013518 | |
| Domain | IRK | 1.01e-16 | 16 | 61 | 8 | PF01007 | |
| Domain | - | 1.01e-16 | 16 | 61 | 8 | 2.60.40.1400 | |
| Domain | K_chnl_inward-rec_Kir | 1.01e-16 | 16 | 61 | 8 | IPR016449 | |
| Domain | Ig_E-set | 4.93e-11 | 104 | 61 | 9 | IPR014756 | |
| Domain | K_chnl_inward-rec_Kir_N | 3.31e-08 | 3 | 61 | 3 | IPR013673 | |
| Domain | IRK_N | 3.31e-08 | 3 | 61 | 3 | PF08466 | |
| Domain | NAP | 2.37e-07 | 17 | 61 | 4 | PF00956 | |
| Domain | NAP_family | 2.37e-07 | 17 | 61 | 4 | IPR002164 | |
| Domain | K_chnl_inward-rec_Kir2.2 | 1.05e-05 | 2 | 61 | 2 | IPR003272 | |
| Domain | Zfx_Zfy_act | 3.14e-05 | 3 | 61 | 2 | PF04704 | |
| Domain | Transcrp_activ_Zfx/Zfy-dom | 3.14e-05 | 3 | 61 | 2 | IPR006794 | |
| Domain | Calx_beta | 2.90e-04 | 8 | 61 | 2 | SM00237 | |
| Domain | Calx_beta | 3.72e-04 | 9 | 61 | 2 | IPR003644 | |
| Domain | Calx-beta | 3.72e-04 | 9 | 61 | 2 | PF03160 | |
| Domain | SEA | 9.31e-04 | 14 | 61 | 2 | SM00200 | |
| Domain | EGF_1 | 1.46e-03 | 255 | 61 | 5 | PS00022 | |
| Domain | EGF-like_CS | 1.61e-03 | 261 | 61 | 5 | IPR013032 | |
| Domain | EGF_2 | 1.72e-03 | 265 | 61 | 5 | PS01186 | |
| Domain | 4_helix_cytokine-like_core | 1.82e-03 | 74 | 61 | 3 | IPR009079 | |
| Domain | SEA | 2.54e-03 | 23 | 61 | 2 | PS50024 | |
| Domain | SEA_dom | 2.54e-03 | 23 | 61 | 2 | IPR000082 | |
| Domain | ARF | 4.02e-03 | 29 | 61 | 2 | PS51417 | |
| Domain | Small_GTPase_ARF | 4.02e-03 | 29 | 61 | 2 | IPR024156 | |
| Domain | Arf | 4.59e-03 | 31 | 61 | 2 | PF00025 | |
| Domain | Small_GTPase_ARF/SAR | 5.19e-03 | 33 | 61 | 2 | IPR006689 | |
| Pathway | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | 8.71e-14 | 36 | 42 | 8 | MM14544 | |
| Pathway | REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS | 2.38e-12 | 30 | 42 | 7 | MM14542 | |
| Pathway | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | 7.79e-12 | 35 | 42 | 7 | M1075 | |
| Pathway | REACTOME_GABA_B_RECEPTOR_ACTIVATION | 4.35e-11 | 44 | 42 | 7 | MM15709 | |
| Pathway | REACTOME_POTASSIUM_CHANNELS | 3.96e-10 | 98 | 42 | 8 | MM14545 | |
| Pathway | REACTOME_GABA_RECEPTOR_ACTIVATION | 4.24e-10 | 60 | 42 | 7 | MM15708 | |
| Pathway | REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL | 2.07e-09 | 19 | 42 | 5 | MM15194 | |
| Pathway | REACTOME_GABA_B_RECEPTOR_ACTIVATION | 2.71e-09 | 43 | 42 | 6 | M954 | |
| Pathway | REACTOME_POTASSIUM_CHANNELS | 1.98e-08 | 103 | 42 | 7 | M1073 | |
| Pathway | REACTOME_GABA_RECEPTOR_ACTIVATION | 2.14e-08 | 60 | 42 | 6 | M976 | |
| Pathway | REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION | 2.01e-07 | 144 | 42 | 7 | MM14501 | |
| Pathway | REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL | 2.55e-07 | 19 | 42 | 4 | M27452 | |
| Pathway | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 2.63e-06 | 211 | 42 | 7 | MM14502 | |
| Pathway | REACTOME_NEURONAL_SYSTEM | 5.46e-06 | 335 | 42 | 8 | MM14503 | |
| Pathway | REACTOME_MUSCLE_CONTRACTION | 8.69e-06 | 165 | 42 | 6 | MM15026 | |
| Pathway | REACTOME_CARDIAC_CONDUCTION | 1.30e-05 | 103 | 42 | 5 | MM15196 | |
| Pathway | REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION | 2.98e-05 | 205 | 42 | 6 | M752 | |
| Pathway | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 1.37e-04 | 270 | 42 | 6 | M15514 | |
| Pathway | REACTOME_NEURONAL_SYSTEM | 1.90e-04 | 411 | 42 | 7 | M735 | |
| Pathway | WP_GENES_RELATED_TO_PRIMARY_CILIUM_DEVELOPMENT_BASED_ON_CRISPR | 2.43e-04 | 103 | 42 | 4 | M39826 | |
| Pathway | REACTOME_MUSCLE_CONTRACTION | 3.25e-04 | 203 | 42 | 5 | M5485 | |
| Pathway | REACTOME_CARDIAC_CONDUCTION | 5.89e-04 | 130 | 42 | 4 | M27454 | |
| Pubmed | 3.36e-17 | 6 | 65 | 6 | 7580148 | ||
| Pubmed | 3.63e-16 | 15 | 65 | 7 | 16382105 | ||
| Pubmed | Rare independent mutations in renal salt handling genes contribute to blood pressure variation. | 9.52e-15 | 22 | 65 | 7 | 18391953 | |
| Pubmed | 5.79e-12 | 25 | 65 | 6 | 17185339 | ||
| Pubmed | Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2. | 1.11e-11 | 4 | 65 | 4 | 15958527 | |
| Pubmed | 1.11e-11 | 4 | 65 | 4 | 20798526 | ||
| Pubmed | 5.55e-11 | 5 | 65 | 4 | 7926018 | ||
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 8083233 | ||
| Pubmed | Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1. | 6.23e-09 | 3 | 65 | 3 | 16258766 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 11410627 | ||
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 17640933 | ||
| Pubmed | Differential polyamine sensitivity in inwardly rectifying Kir2 potassium channels. | 6.23e-09 | 3 | 65 | 3 | 16373386 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 10904001 | ||
| Pubmed | Identification of GIRK2-4 subunits in human esophageal smooth muscle cells. | 6.23e-09 | 3 | 65 | 3 | 21637918 | |
| Pubmed | Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome. | 6.23e-09 | 3 | 65 | 3 | 12032359 | |
| Pubmed | 6.23e-09 | 3 | 65 | 3 | 12499858 | ||
| Pubmed | 2.49e-08 | 4 | 65 | 3 | 11891065 | ||
| Pubmed | Co-expression of human Kir3 subunits can yield channels with different functional properties. | 2.49e-08 | 4 | 65 | 3 | 10659995 | |
| Pubmed | Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum. | 2.49e-08 | 4 | 65 | 3 | 18088366 | |
| Pubmed | Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels. | 2.49e-08 | 4 | 65 | 3 | 7499385 | |
| Pubmed | Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines. | 2.49e-08 | 4 | 65 | 3 | 16109170 | |
| Pubmed | Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells. | 2.49e-08 | 4 | 65 | 3 | 8630252 | |
| Pubmed | PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis. | 3.33e-08 | 18 | 65 | 4 | 21511879 | |
| Pubmed | 6.21e-08 | 5 | 65 | 3 | 32541000 | ||
| Pubmed | 6.21e-08 | 5 | 65 | 3 | 19558451 | ||
| Pubmed | 6.21e-08 | 5 | 65 | 3 | 16177047 | ||
| Pubmed | 6.21e-08 | 5 | 65 | 3 | 29326130 | ||
| Pubmed | Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97. | 6.21e-08 | 5 | 65 | 3 | 11181181 | |
| Pubmed | Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. | 2.49e-07 | 139 | 65 | 6 | 16985003 | |
| Pubmed | 5.19e-07 | 9 | 65 | 3 | 12297500 | ||
| Pubmed | 7.41e-07 | 10 | 65 | 3 | 14960569 | ||
| Pubmed | Functional consequences of Kir2.1/Kir2.2 subunit heteromerization. | 3.44e-06 | 2 | 65 | 2 | 20676672 | |
| Pubmed | An Exceptional Gene: Evolution of the TSPY Gene Family in Humans and Other Great Apes. | 3.44e-06 | 2 | 65 | 2 | 24710137 | |
| Pubmed | Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice. | 3.44e-06 | 2 | 65 | 2 | 18400906 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 9334251 | ||
| Pubmed | Structure and function of TSPY, the Y-chromosome gene coding for the "testis-specific protein". | 3.44e-06 | 2 | 65 | 2 | 9678360 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 29974883 | ||
| Pubmed | A discrete alcohol pocket involved in GIRK channel activation. | 3.44e-06 | 2 | 65 | 2 | 19561601 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 12716983 | ||
| Pubmed | Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family. | 3.44e-06 | 2 | 65 | 2 | 9126493 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 17890431 | ||
| Pubmed | Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes. | 3.44e-06 | 2 | 65 | 2 | 19329779 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 12958310 | ||
| Pubmed | Molecular cloning of cDNAs derived from a novel human intestinal mucin gene. | 3.44e-06 | 2 | 65 | 2 | 2393399 | |
| Pubmed | Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse. | 3.44e-06 | 2 | 65 | 2 | 15705530 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 11289722 | ||
| Pubmed | Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs. | 3.44e-06 | 2 | 65 | 2 | 1970799 | |
| Pubmed | Evolution of the Zfx and Zfy genes: rates and interdependence between the genes. | 3.44e-06 | 2 | 65 | 2 | 8487630 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 20921230 | ||
| Pubmed | Dual-mode phospholipid regulation of human inward rectifying potassium channels. | 3.44e-06 | 2 | 65 | 2 | 21281576 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 26520451 | ||
| Pubmed | Plasticity of KIR channels in human smooth muscle cells from internal thoracic artery. | 3.44e-06 | 2 | 65 | 2 | 12598232 | |
| Pubmed | Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene. | 3.44e-06 | 2 | 65 | 2 | 1691708 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 8188262 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 15241014 | ||
| Pubmed | Ethanol opens G-protein-activated inwardly rectifying K+ channels. | 3.44e-06 | 2 | 65 | 2 | 10570486 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 8244388 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 2308929 | ||
| Pubmed | Mapping the human ZFX locus to Xp21.3 by in situ hybridization. | 3.44e-06 | 2 | 65 | 2 | 2497060 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 35314385 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 28251288 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 18702733 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 25885757 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 10956667 | ||
| Pubmed | Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY. | 3.44e-06 | 2 | 65 | 2 | 2041734 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 8318216 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 2105457 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 34324278 | ||
| Pubmed | Zfx mutation results in small animal size and reduced germ cell number in male and female mice. | 3.44e-06 | 2 | 65 | 2 | 9187153 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 12040038 | ||
| Pubmed | Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B. | 3.44e-06 | 2 | 65 | 2 | 10973822 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 28487514 | ||
| Pubmed | [Expression of Zfx in mouse testicular spermatogenic cells]. | 3.44e-06 | 2 | 65 | 2 | 38602753 | |
| Pubmed | The MUC3 gene encodes a transmembrane mucin and is alternatively spliced. | 3.44e-06 | 2 | 65 | 2 | 10405327 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 20301441 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 2265557 | ||
| Pubmed | 5.91e-06 | 19 | 65 | 3 | 15024025 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 26786162 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 7702616 | ||
| Pubmed | Zfy gene expression patterns are not compatible with a primary role in mouse sex determination. | 1.03e-05 | 3 | 65 | 2 | 2480529 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 10627592 | ||
| Pubmed | Behavioral characterization of mice lacking GIRK/Kir3 channel subunits. | 1.03e-05 | 3 | 65 | 2 | 18194467 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 9459542 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 12479614 | ||
| Pubmed | Isolation of monochromosomal hybrids for mouse chromosomes 3, 6, 10, 12, 14, and 18. | 1.03e-05 | 3 | 65 | 2 | 9060403 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 38310188 | ||
| Pubmed | Expression of mucin 3 and mucin 5AC in arthritic synovial tissue. | 1.03e-05 | 3 | 65 | 2 | 18163520 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 12034888 | ||
| Pubmed | YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome. | 1.03e-05 | 3 | 65 | 2 | 8406471 | |
| Pubmed | Molecular and cellular diversity of neuronal G-protein-gated potassium channels. | 1.03e-05 | 3 | 65 | 2 | 16339040 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 11299520 | ||
| Pubmed | Altered neurotransmission in the mesolimbic reward system of Girk mice. | 1.03e-05 | 3 | 65 | 2 | 20557431 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 22098295 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 15028774 | ||
| Pubmed | Neuronal vulnerability in mouse models of Huntington's disease: membrane channel protein changes. | 1.03e-05 | 3 | 65 | 2 | 15880743 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 32406922 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 10512748 | ||
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 8921409 | ||
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 15142872 | ||
| Pubmed | ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia. | 2.06e-05 | 4 | 65 | 2 | 24485662 | |
| Interaction | TSPY8 interactions | 2.64e-08 | 3 | 61 | 3 | int:TSPY8 | |
| Interaction | KCNJ18 interactions | 1.05e-07 | 4 | 61 | 3 | int:KCNJ18 | |
| Interaction | DLG2 interactions | 5.21e-06 | 83 | 61 | 5 | int:DLG2 | |
| Interaction | KCNJ2 interactions | 7.80e-06 | 42 | 61 | 4 | int:KCNJ2 | |
| Interaction | KCNJ3 interactions | 2.08e-05 | 18 | 61 | 3 | int:KCNJ3 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chrYp11 | 4.64e-11 | 150 | 65 | 8 | chrYp11 | |
| Cytoband | Yp11.2 | 7.59e-11 | 94 | 65 | 7 | Yp11.2 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr7p21 | 2.82e-04 | 89 | 65 | 3 | chr7p21 | |
| Cytoband | 7q22 | 1.34e-03 | 38 | 65 | 2 | 7q22 | |
| GeneFamily | Potassium voltage-gated channel subfamily J | 6.51e-18 | 16 | 43 | 8 | 276 | |
| GeneFamily | CD molecules|Mucins | 1.13e-03 | 21 | 43 | 2 | 648 | |
| GeneFamily | Ring finger proteins|Tripartite motif containing|ARF GTPase family | 2.46e-03 | 31 | 43 | 2 | 357 | |
| ToppCell | TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_or_Epithelioid_Leiomyosarcoma-7|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9 | 3.20e-07 | 99 | 64 | 5 | 4f0346fe85ba006d1ab28a61624568522ffe5cb4 | |
| Computational | Ion channels. | 5.17e-05 | 70 | 32 | 4 | MODULE_316 | |
| Drug | rubidium | 3.28e-12 | 61 | 59 | 8 | CID000105153 | |
| Drug | A13108 | 2.45e-11 | 10 | 59 | 5 | CID000062278 | |
| Drug | barium chloride dihydrate | 1.32e-09 | 43 | 59 | 6 | CID000025157 | |
| Drug | Barium permanganate | 1.89e-09 | 133 | 59 | 8 | CID000024587 | |
| Drug | CsCl | 2.26e-09 | 136 | 59 | 8 | CID000024293 | |
| Drug | BaCl2 | 5.47e-09 | 54 | 59 | 6 | CID000025204 | |
| Drug | CID5255110 | 7.64e-09 | 57 | 59 | 6 | CID005255110 | |
| Drug | Rubidium chromate | 3.77e-08 | 74 | 59 | 6 | CID000061605 | |
| Drug | pinacidil | 1.00e-07 | 87 | 59 | 6 | CID000004826 | |
| Drug | cromakalim | 1.07e-07 | 88 | 59 | 6 | CID000071191 | |
| Drug | barium | 1.09e-07 | 148 | 59 | 7 | CID000104810 | |
| Drug | diazoxide | 1.24e-07 | 227 | 59 | 8 | CID000003019 | |
| Drug | Potassium | 3.26e-07 | 106 | 59 | 6 | ctd:D011188 | |
| Drug | Barium | 1.20e-06 | 72 | 59 | 5 | ctd:D001464 | |
| Drug | 1 sulfonylurea | 1.89e-06 | 143 | 59 | 6 | CID011819083 | |
| Drug | cyanide | 4.12e-06 | 254 | 59 | 7 | CID000000768 | |
| Drug | bifeprunox | 4.64e-06 | 13 | 59 | 3 | CID000208951 | |
| Drug | methanethiosulfonate | 7.09e-06 | 103 | 59 | 5 | CID004188587 | |
| Drug | baclofen | 1.00e-05 | 191 | 59 | 6 | CID000002284 | |
| Drug | GTP[S] | 1.99e-05 | 591 | 59 | 9 | CID000001764 | |
| Drug | tetraethylammonium | 3.31e-05 | 236 | 59 | 6 | CID000005413 | |
| Drug | TlBr | 3.95e-05 | 4 | 59 | 2 | CID006432719 | |
| Drug | 4-AP | 5.44e-05 | 258 | 59 | 6 | CID000001727 | |
| Drug | glibenclamide | 5.71e-05 | 382 | 59 | 7 | CID000003488 | |
| Drug | GDP-b-S | 6.29e-05 | 162 | 59 | 5 | CID000643998 | |
| Drug | milnacipran | 6.38e-05 | 30 | 59 | 3 | CID000055480 | |
| Drug | triphosphoinositide | 7.44e-05 | 273 | 59 | 6 | CID009543520 | |
| Drug | 4,4'-thiodiphenol | 7.77e-05 | 32 | 59 | 3 | CID000017570 | |
| Drug | YM-09151-2 | 7.77e-05 | 32 | 59 | 3 | CID000004452 | |
| Drug | doyle | 8.06e-05 | 88 | 59 | 4 | CID000002245 | |
| Drug | KRS-5 | 9.84e-05 | 6 | 59 | 2 | CID000062677 | |
| Drug | AC1MHW5N | 1.11e-04 | 36 | 59 | 3 | CID003058747 | |
| Drug | beta-FNA | 1.41e-04 | 39 | 59 | 3 | CID005137129 | |
| Drug | sodium | KCNJ2 GYG1 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ12 OSCP1 NDUFAB1 NOMO1 | 1.42e-04 | 944 | 59 | 10 | CID000000923 |
| Drug | Duloxetine Hydrochloride | 1.83e-04 | 8 | 59 | 2 | ctd:D000068736 | |
| Drug | Amoxapine | 2.35e-04 | 9 | 59 | 2 | ctd:D000657 | |
| Disease | Andersen Syndrome | 3.41e-06 | 2 | 55 | 2 | C1563715 | |
| Disease | frontal theta oscillation measurement | 2.63e-04 | 13 | 55 | 2 | EFO_0004800 | |
| Disease | Cardiac Arrhythmia | 9.96e-04 | 25 | 55 | 2 | C0003811 | |
| Disease | heart rate response to exercise | 2.93e-03 | 43 | 55 | 2 | EFO_0009184 | |
| Disease | fibrinogen measurement, coronary artery disease | 3.00e-03 | 154 | 55 | 3 | EFO_0001645, EFO_0004623 | |
| Disease | left ventricular systolic function measurement | 3.07e-03 | 44 | 55 | 2 | EFO_0008206 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| VEIIMAMEDEFGFEI | 116 | O14561 | |
| FISREEGEVGEEIEM | 1571 | Q96L96 | |
| IVFVVDSVDVERMEE | 96 | P40617 | |
| IMINREEGVVFIEID | 1106 | Q9C0A0 | |
| AEELVFEGIMEVCQF | 651 | Q9UKA4 | |
| GVIFVVDSSDEERME | 91 | Q3SXY8 | |
| VAMVLDEEAEVFIVK | 811 | P49756 | |
| ERDDFEIVVILEGMV | 266 | Q92806 | |
| DFEIVVILEGMVEAT | 291 | P63252 | |
| SEDFEIVVILEGMVE | 281 | P48050 | |
| QEEFEVVVILEGMVE | 296 | P48544 | |
| DDFEIVVILEGMVEA | 291 | Q14500 | |
| ELEIVVILEGMVEAT | 301 | P48051 | |
| VEIEVTFDGVREMRE | 2321 | Q5SZK8 | |
| NLVAMDELVEVGDVE | 641 | Q8N187 | |
| ECVMELEGLEVVVEA | 951 | O43157 | |
| AGAFTDVMVVVDIID | 1736 | Q9NYQ8 | |
| DLDVVETEVGMEVSV | 3016 | Q02505 | |
| EVIAVVMDVFTDIDI | 161 | Q9H4H8 | |
| LEVEVLEDDMSAVEF | 571 | Q15155 | |
| ENMEGLFLAVDEIVD | 116 | P61923 | |
| GMVEFQEGVELVDVR | 931 | P16144 | |
| DFELVVILEGMVEAT | 296 | Q9UNX9 | |
| NMERFAEEADVVIVG | 61 | Q16134 | |
| LETVFDEVIMVDVLD | 51 | P46976 | |
| VDMVEEIDHIGIISF | 171 | P01031 | |
| METEQLGVEIFETAD | 21 | Q6V1X1 | |
| DVVMEDIIGDVQIYD | 251 | Q6UXX5 | |
| ELICEIMLVAEGFIE | 2001 | Q9NYC9 | |
| LFEQVAGEDMEVTAE | 526 | O14815 | |
| EDDLVLEVVIMIGTV | 561 | Q92845 | |
| ELAEMIDVVLTAEGE | 26 | Q3ZCT8 | |
| VEQVDLDVVETEVGM | 926 | Q9H195 | |
| LDVVETEVGMEVSVD | 931 | Q9H195 | |
| DFTMVEEVAEVDAVV | 401 | Q8TAK5 | |
| DDFEIVVILEGMVEA | 291 | B7U540 | |
| EDLVDTFFEVEVEME | 191 | Q9Y5W8 | |
| MIFEVVEQAGAIILE | 296 | Q8TEU7 | |
| VDLAEMVVEAEIFPV | 241 | O75602 | |
| EVGVEEIALMNEDSI | 126 | P05015 | |
| VGVTEELEDFIMLLE | 251 | Q7LGA3 | |
| TAIFEEMIEDEEGLV | 1266 | Q149N8 | |
| EGEDEEEAMVVAVIP | 21 | Q9BUA3 | |
| SEELARIMGEFEITE | 356 | Q8WVF1 | |
| MEPLDEEISGIVEVV | 56 | P35244 | |
| VAEAVETGEEDVIME | 6 | Q9NPQ8 | |
| EVMFLGEIEEILDVI | 326 | Q15172 | |
| EEALEGLEVMDVFLR | 696 | Q9P2E5 | |
| EEEEIGEDSQFMILA | 1196 | Q9HAW4 | |
| EVMGIVTLEDIIEEI | 546 | Q9NRU3 | |
| LLDDIMAEVEVVAEV | 66 | A0A494C1R9 | |
| MAEVEVVAEVEVVAE | 71 | A0A494C1R9 | |
| MAEVEVVAEEEGLVE | 71 | P0CW01 | |
| MAEVEVVAEEEGLVE | 71 | A6NKD2 | |
| LLDDIMAEVEVVAEV | 66 | P0CV99 | |
| MAEVEVVAEVEVVAE | 71 | P0CV99 | |
| MVYIDEIDVDQEGIA | 61 | Q8TAM2 | |
| MAEVEVVAEEEGLVE | 71 | Q01534 | |
| AVLIDMEEGVVNEIL | 71 | Q9UJT0 | |
| EVIVDVESMDIFPVG | 451 | Q5VUG0 | |
| EEELDFRAVVMDEVV | 36 | Q9ULI2 | |
| VFGIMQVEEVEEEED | 66 | Q14166 | |
| MAEVEVVAEEEGLVE | 71 | P0CV98 | |
| MAEVEVVAEEEGLVE | 71 | P0CW00 | |
| AEIADEVYMEVIVGE | 316 | P17010 | |
| EVYMEVIVGEEDAAA | 321 | P17010 | |
| VAEIADEVYMEVIVG | 311 | P08048 | |
| QVFVGDRVEMAVEVS | 356 | Q14324 | |
| GEMAIEVFELAENED | 641 | Q96SB3 |