Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 ZNF497 RARA RARB BCL6 ZNF519 WIZ ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2 YY2	2.97e-13	1459	39	20	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 RARA RARB BCL6 ZNF519 WIZ ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2 YY2	2.16e-12	1412	39	19	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 ZNF497 RARA RARB BCL6 ZNF519 WIZ ZNF789 ZIC5 MZF1 ZNF416 ZIC1 ZIC2 YY2	3.15e-12	1244	39	18	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 ZNF497 RARA RARB BCL6 ZNF519 WIZ ZNF789 ZIC5 MZF1 ZNF416 ZIC1 ZIC2 YY2	4.52e-12	1271	39	18	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZFP42 ZNF519 MZF1 CASZ1 ZIC1 ZIC2 YY2	9.27e-05	560	39	7	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZFP42 ZNF519 MZF1 CASZ1 ZIC1 ZIC2 YY2	9.91e-05	566	39	7	GO:0001216
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBLN2 FBN2	2.42e-04	12	39	2	GO:0030023
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBLN2 FBN2	3.33e-04	14	39	2	GO:0097493
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMA2 COL11A2 FBLN2 FBN2	4.84e-04	188	39	4	GO:0005201
GeneOntologyMolecularFunction	transcription coregulator binding	RARA BCL6 WIZ	2.56e-03	140	39	3	GO:0001221
GeneOntologyMolecularFunction	chromatin DNA binding	RARA BCL6 ZIC2	4.21e-03	167	39	3	GO:0031490
GeneOntologyMolecularFunction	transcription corepressor binding	BCL6 WIZ	5.93e-03	59	39	2	GO:0001222
GeneOntologyMolecularFunction	nuclear receptor activity	RARA RARB	6.13e-03	60	39	2	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	RARA RARB	6.33e-03	61	39	2	GO:0098531
GeneOntologyMolecularFunction	structural molecule activity	LAMA2 LAMC3 CRYGS COL11A2 FBLN2 FBN2	7.18e-03	891	39	6	GO:0005198
GeneOntologyBiologicalProcess	neural tube closure	LRP2 RARA ZIC5 ZIC2	6.06e-05	113	39	4	GO:0001843
GeneOntologyBiologicalProcess	tube closure	LRP2 RARA ZIC5 ZIC2	6.27e-05	114	39	4	GO:0060606
GeneOntologyBiologicalProcess	primary neural tube formation	LRP2 RARA ZIC5 ZIC2	7.66e-05	120	39	4	GO:0014020
GeneOntologyBiologicalProcess	neural tube formation	LRP2 RARA ZIC5 ZIC2	1.17e-04	134	39	4	GO:0001841
GeneOntologyBiologicalProcess	embryonic epithelial tube formation	LRP2 RARA ZIC5 ZIC2	2.27e-04	159	39	4	GO:0001838
GeneOntologyBiologicalProcess	embryo development	LRP2 LAMA2 ZFP42 FBN2 RARA RARB ZIC5 PIK3CB ZIC1 ZIC2	2.57e-04	1437	39	10	GO:0009790
GeneOntologyBiologicalProcess	regulation of T-helper 2 cell differentiation	RARA BCL6	3.12e-04	14	39	2	GO:0045628
GeneOntologyBiologicalProcess	epithelial tube formation	LRP2 RARA ZIC5 ZIC2	3.13e-04	173	39	4	GO:0072175
GeneOntologyBiologicalProcess	central nervous system development	LRP2 ZIC4 LAMC3 RARA RARB ZIC5 MOG ZIC1 ZIC2	3.15e-04	1197	39	9	GO:0007417
GeneOntologyBiologicalProcess	embryonic morphogenesis	LRP2 FBN2 RARA RARB ZIC5 ZIC1 ZIC2	3.36e-04	713	39	7	GO:0048598
GeneOntologyBiologicalProcess	regulation of nuclear cell cycle DNA replication	BCL6 WIZ	3.60e-04	15	39	2	GO:0033262
GeneOntologyBiologicalProcess	tube formation	LRP2 RARA ZIC5 ZIC2	4.20e-04	187	39	4	GO:0035148
GeneOntologyBiologicalProcess	morphogenesis of embryonic epithelium	LRP2 RARA ZIC5 ZIC2	4.46e-04	190	39	4	GO:0016331
GeneOntologyBiologicalProcess	animal organ morphogenesis	LRP2 LAMA2 LAMC3 COL11A2 FBN2 RARA RARB CASZ1 ZIC1	4.85e-04	1269	39	9	GO:0009887
GeneOntologyBiologicalProcess	neural tube development	LRP2 RARA ZIC5 ZIC2	5.62e-04	202	39	4	GO:0021915
GeneOntologyBiologicalProcess	ventricular cardiac muscle cell differentiation	RARA RARB	5.84e-04	19	39	2	GO:0055012
MousePheno	postnatal growth retardation	ZNF462 LAMA2 COL11A2 FBN2 RARA RARB BCL6 PIK3CB ZIC1	8.60e-05	881	31	9	MP:0001732
MousePheno	lethality during fetal growth through weaning, incomplete penetrance	LRP2 LAMA2 ZIC4 RARA HERC2 CLXN BCL6 WIZ PIK3CB ZIC1	1.00e-04	1124	31	10	MP:0011112
MousePheno	abnormal postnatal growth	ZNF462 LAMA2 COL11A2 FBN2 RARA RARB BCL6 PIK3CB ZIC1	1.08e-04	907	31	9	MP:0001731
MousePheno	abnormal axial skeleton morphology	LRP2 LAMA2 COL11A2 FBN2 RARA RARB WIZ ZIC5 PIK3CB ZIC1 ZIC2	1.79e-04	1458	31	11	MP:0002114
MousePheno	abnormal joint morphology	LAMA2 COL11A2 FBN2 RARA RARB ZIC2	2.04e-04	397	31	6	MP:0002932
MousePheno	fusion of atlas and odontoid process	RARA RARB	2.12e-04	10	31	2	MP:0010701
MousePheno	cerebellum vermis hypoplasia	ZIC4 ZIC1	2.12e-04	10	31	2	MP:0000866
MousePheno	abnormal cranium morphology	LRP2 LAMA2 COL11A2 FBN2 RARA RARB WIZ ZIC5	3.01e-04	813	31	8	MP:0000438
MousePheno	fusion of vertebral arches	RARA RARB ZIC2	3.26e-04	61	31	3	MP:0004613
MousePheno	abnormal craniofacial bone morphology	LRP2 LAMA2 COL11A2 FBN2 RARA RARB WIZ ZIC5	3.38e-04	827	31	8	MP:0002116
MousePheno	vertebral fusion	FBN2 RARA RARB ZIC2	4.39e-04	163	31	4	MP:0004609
MousePheno	abnormal lateral ventricle morphology	LRP2 CLXN ZIC5 ZIC2	4.49e-04	164	31	4	MP:0000823
MousePheno	micrognathia	LRP2 FBN2 ZIC5	4.49e-04	68	31	3	MP:0002639
MousePheno	abnormal cerebellar cortex morphology	LRP2 ZIC4 PRKCG HERC2 ZIC1	4.73e-04	300	31	5	MP:0004097
MousePheno	fused joints	FBN2 RARA RARB ZIC2	5.14e-04	170	31	4	MP:0003189
MousePheno	abnormal vertebral arch morphology	FBN2 RARA RARB ZIC2	5.61e-04	174	31	4	MP:0004599
MousePheno	abnormal forehead shape	LRP2 COL11A2	6.34e-04	17	31	2	MP:0030045
MousePheno	abnormal odontoid process morphology	RARA RARB	7.12e-04	18	31	2	MP:0004659
Domain	ZINC_FINGER_C2H2_2	ZNF462 ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 ZNF497 BCL6 ZNF519 WIZ ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2 YY2	1.40e-16	775	39	19	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF462 ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 ZNF497 BCL6 ZNF519 WIZ ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2 YY2	1.47e-16	777	39	19	PS00028
Domain	Znf_C2H2	ZNF462 ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 ZNF497 BCL6 ZNF519 WIZ ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2 YY2	2.82e-16	805	39	19	IPR007087
Domain	ZnF_C2H2	ZNF462 ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 ZNF497 BCL6 ZNF519 WIZ ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2 YY2	3.02e-16	808	39	19	SM00355
Domain	Znf_C2H2-like	ZNF462 ZNF74 ZIC4 ZFP42 ZFP92 ZNF497 BCL6 ZNF519 WIZ ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2 YY2	4.79e-15	796	39	18	IPR015880
Domain	-	ZNF462 ZNF74 ZIC4 ZFP42 ZFP92 ZNF497 BCL6 ZNF519 ZNF789 ZNF337 ZIC5 MZF1 ZNF416 ZIC1 ZIC2 YY2	1.35e-13	679	39	16	3.30.160.60
Domain	zf-C2H2	ZNF462 ZNF74 ZIC4 ZFP92 ZNF275 ZNF497 BCL6 ZNF519 ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2	1.85e-13	693	39	16	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF462 ZNF74 ZIC4 ZFP42 ZFP92 ZNF497 BCL6 ZNF519 ZNF789 ZNF337 ZIC5 MZF1 ZNF416 ZIC1 ZIC2 YY2	1.89e-13	694	39	16	IPR013087
Domain	KRAB	ZNF74 ZFP92 ZNF275 ZNF519 ZNF789 ZNF337 ZNF416	8.13e-06	358	39	7	PS50805
Domain	KRAB	ZNF74 ZFP92 ZNF275 ZNF519 ZNF789 ZNF337 ZNF416	8.13e-06	358	39	7	PF01352
Domain	KRAB	ZNF74 ZFP92 ZNF275 ZNF519 ZNF789 ZNF337 ZNF416	9.90e-06	369	39	7	SM00349
Domain	KRAB	ZNF74 ZFP92 ZNF275 ZNF519 ZNF789 ZNF337 ZNF416	1.01e-05	370	39	7	IPR001909
Domain	cEGF	LRP2 FBLN2 FBN2	2.12e-05	26	39	3	IPR026823
Domain	cEGF	LRP2 FBLN2 FBN2	2.12e-05	26	39	3	PF12662
Domain	Retinoic_acid_rcpt	RARA RARB	2.54e-05	4	39	2	IPR003078
Domain	LAMININ_IVA	LAMA2 LAMC3	1.18e-04	8	39	2	PS51115
Domain	Laminin_B	LAMA2 LAMC3	1.18e-04	8	39	2	PF00052
Domain	LamB	LAMA2 LAMC3	1.18e-04	8	39	2	SM00281
Domain	Laminin_IV	LAMA2 LAMC3	1.18e-04	8	39	2	IPR000034
Domain	EGF	LRP2 LAMA2 LAMC3 FBLN2 FBN2	1.23e-04	235	39	5	SM00181
Domain	EGF-like_dom	LRP2 LAMA2 LAMC3 FBLN2 FBN2	1.61e-04	249	39	5	IPR000742
Domain	EGF_1	LRP2 LAMA2 LAMC3 FBLN2 FBN2	1.80e-04	255	39	5	PS00022
Domain	EGF-like_CS	LRP2 LAMA2 LAMC3 FBLN2 FBN2	2.00e-04	261	39	5	IPR013032
Domain	EGF_2	LRP2 LAMA2 LAMC3 FBLN2 FBN2	2.15e-04	265	39	5	PS01186
Domain	Growth_fac_rcpt_	LRP2 LAMC3 FBLN2 FBN2	3.07e-04	156	39	4	IPR009030
Domain	-	LAMA2 LAMC3 HERC2	4.73e-04	73	39	3	2.60.120.260
Domain	LAMININ_NTER	LAMA2 LAMC3	5.01e-04	16	39	2	PS51117
Domain	Laminin_N	LAMA2 LAMC3	5.01e-04	16	39	2	PF00055
Domain	Laminin_N	LAMA2 LAMC3	5.01e-04	16	39	2	IPR008211
Domain	LamNT	LAMA2 LAMC3	5.01e-04	16	39	2	SM00136
Domain	EGF_CA	LRP2 FBLN2 FBN2	7.64e-04	86	39	3	PF07645
Domain	Galactose-bd-like	LAMA2 LAMC3 HERC2	9.89e-04	94	39	3	IPR008979
Domain	EGF_Ca-bd_CS	LRP2 FBLN2 FBN2	1.08e-03	97	39	3	IPR018097
Domain	EGF_CA	LRP2 FBLN2 FBN2	1.15e-03	99	39	3	PS01187
Domain	ASX_HYDROXYL	LRP2 FBLN2 FBN2	1.18e-03	100	39	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP2 FBLN2 FBN2	1.40e-03	106	39	3	IPR000152
Domain	EGF_LAM_2	LAMA2 LAMC3	1.78e-03	30	39	2	PS50027
Domain	EGF_LAM_1	LAMA2 LAMC3	1.78e-03	30	39	2	PS01248
Domain	EGF_CA	LRP2 FBLN2 FBN2	2.09e-03	122	39	3	SM00179
Domain	EGF-like_Ca-bd_dom	LRP2 FBLN2 FBN2	2.19e-03	124	39	3	IPR001881
Domain	Laminin_EGF	LAMA2 LAMC3	2.42e-03	35	39	2	PF00053
Domain	EGF_Lam	LAMA2 LAMC3	2.42e-03	35	39	2	SM00180
Domain	Laminin_EGF	LAMA2 LAMC3	2.85e-03	38	39	2	IPR002049
Domain	Laminin_G_2	LAMA2 COL11A2	3.15e-03	40	39	2	PF02210
Domain	LamG	LAMA2 COL11A2	3.80e-03	44	39	2	SM00282
Domain	zf-C2H2_6	ZFP92 ZNF497 ZNF789 ZNF416	4.06e-03	314	39	4	PF13912
Domain	zf-C4	RARA RARB	4.15e-03	46	39	2	PF00105
Domain	NUCLEAR_REC_DBD_1	RARA RARB	4.15e-03	46	39	2	PS00031
Domain	Znf_hrmn_rcpt	RARA RARB	4.15e-03	46	39	2	IPR001628
Domain	Nuclear_hrmn_rcpt	RARA RARB	4.15e-03	46	39	2	IPR001723
Domain	ZnF_C4	RARA RARB	4.15e-03	46	39	2	SM00399
Domain	NUCLEAR_REC_DBD_2	RARA RARB	4.15e-03	46	39	2	PS51030
Domain	-	RARA RARB	4.33e-03	47	39	2	1.10.565.10
Domain	HOLI	RARA RARB	4.51e-03	48	39	2	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	RARA RARB	4.51e-03	48	39	2	IPR000536
Domain	Hormone_recep	RARA RARB	4.51e-03	48	39	2	PF00104
Domain	-	RARA RARB	6.31e-03	57	39	2	3.30.50.10
Domain	Laminin_G	LAMA2 COL11A2	6.52e-03	58	39	2	IPR001791
Domain	Znf_NHR/GATA	RARA RARB	6.52e-03	58	39	2	IPR013088
Domain	EGF_3	LRP2 FBLN2 FBN2	1.29e-02	235	39	3	PS50026
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	LAMA2 LAMC3 RARB PIK3CB	2.15e-05	84	28	4	M3228
Pathway	PID_RETINOIC_ACID_PATHWAY	PRKCG RARA RARB	2.75e-05	30	28	3	M207
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMA2 LAMC3 COL11A2	2.75e-05	30	28	3	M27772
Pathway	KEGG_PATHWAYS_IN_CANCER	LAMA2 PRKCG LAMC3 RARA RARB PIK3CB	3.52e-05	325	28	6	M12868
Pathway	WP_SMALL_CELL_LUNG_CANCER	LAMA2 LAMC3 RARB PIK3CB	3.65e-05	96	28	4	M39834
Pathway	KEGG_FOCAL_ADHESION	LAMA2 PRKCG LAMC3 COL11A2 PIK3CB	4.02e-05	199	28	5	M7253
Pathway	WP_VITAMIN_A1_AND_A5X_PATHWAYS	RARA RARB	5.68e-05	6	28	2	M48097
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA2 LAMC3 COL11A2	7.11e-05	41	28	3	M27778
Pathway	KEGG_NON_SMALL_CELL_LUNG_CANCER	PRKCG RARB PIK3CB	1.63e-04	54	28	3	M19818
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	LAMA2 LAMC3 COL11A2	2.12e-04	59	28	3	M27218
Pathway	WP_MESODERMAL_COMMITMENT_PATHWAY	ZNF462 RARB ZIC5 ZIC2	2.23e-04	153	28	4	M39546
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	LAMA2 LAMC3 COL11A2 FBLN2 FBN2	2.78e-04	300	28	5	M610
Pathway	WP_NONSMALL_CELL_LUNG_CANCER	PRKCG RARB PIK3CB	3.82e-04	72	28	3	M39738
Pathway	WP_CANCER_PATHWAYS	LAMA2 PRKCG LAMC3 RARA RARB PIK3CB	4.03e-04	507	28	6	M48302
Pathway	WP_FOCAL_ADHESION	LAMA2 LAMC3 COL11A2 PIK3CB	4.79e-04	187	28	4	MM15913
Pathway	REACTOME_SIGNALING_BY_MET	LAMA2 LAMC3 COL11A2	5.02e-04	79	28	3	M27643
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMA2 LAMC3 COL11A2	6.00e-04	84	28	3	M7098
Pathway	WP_FOCAL_ADHESION	LAMA2 PRKCG LAMC3 PIK3CB	6.05e-04	199	28	4	M39402
Pathway	WP_NEURAL_CREST_DIFFERENTIATION	COL11A2 ZIC5 ZIC1	9.13e-04	97	28	3	MM15926
Pathway	WP_NEURAL_CREST_DIFFERENTIATION	COL11A2 ZIC5 ZIC1	1.03e-03	101	28	3	M39448
Pathway	PID_RXR_VDR_PATHWAY	RARA RARB	1.20e-03	26	28	2	M162
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMA2 LAMC3	1.60e-03	30	28	2	M27216
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	RARA RARB	1.60e-03	30	28	2	MM15866
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBLN2 FBN2	1.82e-03	32	28	2	MM14854
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	RARA RARB	1.93e-03	33	28	2	MM1448
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	RARA RARB	2.05e-03	34	28	2	M16393
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	RARA RARB	2.17e-03	35	28	2	M39488
Pubmed	Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.	ZIC4 ZIC5 ZIC1 ZIC2	2.02e-11	6	39	4	15465018
Pubmed	Spatiotemporal expression of Zic genes during vertebrate inner ear development.	ZIC4 ZIC5 ZIC1 ZIC2	2.82e-10	10	39	4	23606270
Pubmed	CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.	ZIC4 ZIC5 ZIC1 ZIC2	2.82e-10	10	39	4	18298960
Pubmed	Transcriptional expression of ZICs as an independent indicator of survival in gliomas.	ZIC4 ZIC5 ZIC1	1.30e-09	3	39	3	34475426
Pubmed	Expression of ZIC family genes in meningiomas and other brain tumors.	ZIC5 ZIC1 ZIC2	1.30e-09	3	39	3	20199689
Pubmed	The ZIC gene family in development and disease.	ZIC4 ZIC5 ZIC1	1.30e-09	3	39	3	15733262
Pubmed	Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system.	ZIC4 ZIC1 ZIC2	5.21e-09	4	39	3	15895369
Pubmed	Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci.	LAMA2 ZIC5 ZIC2	4.55e-08	7	39	3	25233373
Pubmed	The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes.	ZIC4 ZIC1 ZIC2	1.09e-07	9	39	3	25178196
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ZIC4 ZFP42 RARA RARB BCL6 ZIC5 ZIC1 YY2	1.37e-07	544	39	8	28473536
Pubmed	Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives.	ZIC5 ZIC1 ZIC2	1.56e-07	10	39	3	15136147
Pubmed	FGF8 signaling patterns the telencephalic midline by regulating putative key factors of midline development.	ZIC4 ZIC1 ZIC2	2.14e-07	11	39	3	18547559
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ZFP42 ZNF275 RARA RARB BCL6 ZNF519 MZF1 ZIC1 ZIC2	4.25e-07	877	39	9	20211142
Pubmed	Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.	RARA RARB	1.23e-06	2	39	2	29921692
Pubmed	Biological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding.	RARA RARB	1.23e-06	2	39	2	24833708
Pubmed	Purification and crystallization of the heterodimeric complex of RARbeta and RXRalpha ligand-binding domains in the active conformation.	RARA RARB	1.23e-06	2	39	2	15159591
Pubmed	[The significance of expression of isoforms RARa1 and RARa2 in response to medicinal therapy and in evaluation of total survival of patients with primarily detected multiple myeloma].	RARA RARB	1.23e-06	2	39	2	30601638
Pubmed	Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter.	ZIC1 ZIC2	1.23e-06	2	39	2	11038359
Pubmed	Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.	ZIC4 ZIC1	1.23e-06	2	39	2	35997131
Pubmed	Reexpression of retinoic acid receptor (RAR) gamma or overexpression of RAR alpha or RAR beta in RAR gamma-null F9 cells reveals a partial functional redundancy between the three RAR types.	RARA RARB	1.23e-06	2	39	2	7644503
Pubmed	Retinoic acid receptors in normal growth and development.	RARA RARB	1.23e-06	2	39	2	1330302
Pubmed	Association between nuclear expression of retinoic acid receptor alpha and beta and clinicopathological features and prognosis of advanced non-small cell lung cancer.	RARA RARB	1.23e-06	2	39	2	27306217
Pubmed	Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations.	RARA RARB	1.23e-06	2	39	2	9168777
Pubmed	Zic-Proteins Are Repressors of Dopaminergic Forebrain Fate in Mice and C. elegans.	ZIC1 ZIC2	1.23e-06	2	39	2	28972122
Pubmed	Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1.	ZFP42 YY2	1.23e-06	2	39	2	17478514
Pubmed	Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum.	ZIC1 ZIC2	1.23e-06	2	39	2	25849986
Pubmed	Behavioral abnormalities of Zic1 and Zic2 mutant mice: implications as models for human neurological disorders.	ZIC1 ZIC2	1.23e-06	2	39	2	11699604
Pubmed	Anticancer effect of retinoic acid via AP-1 activity repression is mediated by retinoic acid receptor alpha and beta in gastric cancer cells.	RARA RARB	1.23e-06	2	39	2	12009305
Pubmed	Dandy-Walker malformation associated with heterozygous ZIC1 and ZIC4 deletion: Report of a new patient.	ZIC4 ZIC1	1.23e-06	2	39	2	21204220
Pubmed	Description of the smallest critical region for Dandy-Walker malformation in chromosome 13 in a girl with a cryptic deletion related to t(6;13)(q23;q32).	ZIC5 ZIC2	1.23e-06	2	39	2	20683983
Pubmed	Retinoic acid regulates gene expression of retinoic acid receptors alpha, beta and gamma in F9 mouse teratocarcinoma cells.	RARA RARB	1.23e-06	2	39	2	1334013
Pubmed	Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.	ZIC4 ZIC1 ZIC2	2.95e-06	25	39	3	15229182
Pubmed	Arg278, but not Lys229 or Lys236, plays an important role in the binding of retinoic acid by retinoic acid receptor gamma.	RARA RARB	3.67e-06	3	39	2	9852056
Pubmed	Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation.	ZIC4 ZIC1	3.67e-06	3	39	2	15338008
Pubmed	Differential expression of retinoic acid receptors in normal and malignant esophageal tissues.	RARA RARB	3.67e-06	3	39	2	15255287
Pubmed	Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants.	RARA RARB	3.67e-06	3	39	2	7607068
Pubmed	Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.	RARA RARB	3.67e-06	3	39	2	7607067
Pubmed	Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia.	RARA RARB	3.67e-06	3	39	2	17244680
Pubmed	Impaired distribution of retinoic acid receptors in the hindgut-tailgut region of murine embryos with anorectal malformations.	RARA RARB	3.67e-06	3	39	2	11172439
Pubmed	Cloning of several genes coding for retinoic acid nuclear receptors in the mouse embryonal carcinoma cell line PCC7-MZ1.	RARA RARB	3.67e-06	3	39	2	8383767
Pubmed	The molecular and genetic dissection of the retinoid signalling pathway.	RARA RARB	3.67e-06	3	39	2	8276261
Pubmed	Characterization and expression of the laminin gamma3 chain: a novel, non-basement membrane-associated, laminin chain.	LAMA2 LAMC3	3.67e-06	3	39	2	10225960
Pubmed	Retinoic acid receptor gamma: specific immunodetection and phosphorylation.	RARA RARB	3.67e-06	3	39	2	1655807
Pubmed	Requirement of retinoic acid receptor isotypes alpha, beta, and gamma during the initial steps of neural differentiation of PCC7 cells.	RARA RARB	3.67e-06	3	39	2	15831518
Pubmed	A redundant oncogenic potential of the retinoic receptor (RAR) alpha, beta and gamma isoforms in acute promyelocytic leukemia.	RARA RARB	3.67e-06	3	39	2	17252005
Pubmed	Immunolocalization of retinoic acid receptors in rat, mouse and human ovary and uterus.	RARA RARB	3.67e-06	3	39	2	8136307
Pubmed	Retinoic acid down-regulation of fibronectin and retinoic acid receptor alpha proteins in NIH-3T3 cells. Blocks of this response by ras transformation.	RARA RARB	3.67e-06	3	39	2	8626453
Pubmed	Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts.	RARA RARB	3.67e-06	3	39	2	24357724
Pubmed	Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein.	RARA BCL6	3.67e-06	3	39	2	9380707
Pubmed	Function of retinoic acid receptor gamma in the mouse.	RARA RARB	3.67e-06	3	39	2	8388780
Pubmed	Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart.	RARA RARB	3.67e-06	3	39	2	9659935
Pubmed	Retinoids and vertebrate development.	RARA RARB	3.67e-06	3	39	2	7910825
Pubmed	Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo.	RARA RARB	3.67e-06	3	39	2	10842077
Pubmed	Retinoic acid and mouse skin morphogenesis. I. Expression pattern of retinoic acid receptor genes during hair vibrissa follicle, plantar, and nasal gland development.	RARA RARB	3.67e-06	3	39	2	8027572
Pubmed	Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity.	RARA RARB	3.67e-06	3	39	2	11245412
Pubmed	mRNA expression pattern of retinoic acid and retinoid X nuclear receptor subtypes in human thyroid papillary carcinoma.	RARA RARB	3.67e-06	3	39	2	23969901
Pubmed	Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin.	RARA RARB	3.67e-06	3	39	2	2544807
Pubmed	[Genetic expression and morphogenesis of the skin in vertebrates].	RARA RARB	3.67e-06	3	39	2	8099268
Pubmed	Regulation of retinoic acid receptor alpha by protein kinase C in B16 mouse melanoma cells.	RARA RARB	3.67e-06	3	39	2	12000751
Pubmed	Altered expression of retinoic acid (RA) receptor mRNAs in the fetal mouse secondary palate by all-trans and 13-cis RAs: implications for RA-induced teratogenesis.	RARA RARB	3.67e-06	3	39	2	10100049
Pubmed	The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells.	ZIC1 ZIC2	3.67e-06	3	39	2	22024047
Pubmed	Specificity of retinoid receptor gene expression in mouse cervical epithelia.	RARA RARB	3.67e-06	3	39	2	8156902
Pubmed	Both retinoic acid receptors alpha (RARalpha) and gamma (RARgamma) are able to initiate mouse upper-lip skin glandular metaplasia.	RARA RARB	3.67e-06	3	39	2	9699718
Pubmed	Mammalian hexokinase 1: evolutionary conservation and structure to function analysis.	RARA RARB	3.67e-06	3	39	2	1783373
Pubmed	Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues.	RARA RARB	3.67e-06	3	39	2	1283441
Pubmed	Characterization of retinoic acid receptor-deficient keratinocytes.	RARA RARB	3.67e-06	3	39	2	10748128
Pubmed	Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs.	RARA RARB	3.67e-06	3	39	2	36446525
Pubmed	Strain difference and mode of inheritance of the susceptibility to passive cutaneous anaphylaxis mediated by allogeneic IgE antibody in the mouse.	RARA RARB	3.67e-06	3	39	2	2737701
Pubmed	Genetic variants in ZIC1, ZIC2, and ZIC3 are not major risk factors for neural tube defects in humans.	ZIC1 ZIC2	3.67e-06	3	39	2	14679585
Pubmed	Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.	RARA RARB	3.67e-06	3	39	2	15528208
Pubmed	Immunohistochemical localization of the retinoic Acid receptors in human prostate.	RARA RARB	3.67e-06	3	39	2	12399530
Pubmed	Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.	RARA RARB	3.67e-06	3	39	2	29848550
Pubmed	Association of retinoic acid receptor genes with meningomyelocele.	RARA RARB	3.67e-06	3	39	2	21254357
Pubmed	BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia.	RARA BCL6	3.67e-06	3	39	2	20807888
Pubmed	Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets.	ZIC1 ZIC2	3.67e-06	3	39	2	20676059
Pubmed	Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes.	RARA RARB	3.67e-06	3	39	2	1655630
Pubmed	Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation.	ZIC1 ZIC2	3.67e-06	3	39	2	15261827
Pubmed	The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired.	ZIC1 ZIC2	3.67e-06	3	39	2	8557628
Pubmed	Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.	BCL6 ZIC1 ZIC2	3.74e-06	27	39	3	33760820
Pubmed	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	LAMA2 TJP2 ZIC2	4.67e-06	29	39	3	23396134
Pubmed	HACE1: A novel repressor of RAR transcriptional activity.	RARA RARB	7.34e-06	4	39	2	19350571
Pubmed	High-depth spatial transcriptome analysis by photo-isolation chemistry.	ZIC4 ZIC1	7.34e-06	4	39	2	34285220
Pubmed	Association of peroxisome proliferator-activated receptors/retinoic acid receptors with renal diseases.	RARA RARB	7.34e-06	4	39	2	24050824
Pubmed	SUMOylation Potentiates ZIC Protein Activity to Influence Murine Neural Crest Cell Specification.	ZIC5 ZIC2	7.34e-06	4	39	2	34638777
Pubmed	Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled.	RARA RARB	7.34e-06	4	39	2	12093741
Pubmed	If the skull fits: magnetic resonance imaging and microcomputed tomography for combined analysis of brain and skull phenotypes in the mouse.	ZIC4 ZIC1	7.34e-06	4	39	2	22947655
Pubmed	Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton.	RARA RARB	7.34e-06	4	39	2	7626396
Pubmed	Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand.	RARA RARB	7.34e-06	4	39	2	8524212
Pubmed	An Evolutionarily Conserved Mesodermal Enhancer in Vertebrate Zic3.	ZIC1 ZIC2	7.34e-06	4	39	2	30297839
Pubmed	Immunolocalization of enzymes, binding proteins, and receptors sufficient for retinoic acid synthesis and signaling during the hair cycle.	RARA RARB	7.34e-06	4	39	2	17363914
Pubmed	Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma.	RARA RARB	7.34e-06	4	39	2	22022577
Pubmed	The retinoid receptors.	RARA RARB	7.34e-06	4	39	2	7967725
Pubmed	Biosynthesis and function of all-trans- and 9-cis-retinoic acid in parathyroid cells.	RARA RARB	7.34e-06	4	39	2	9005841
Pubmed	Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.	LAMA2 FBLN2	7.34e-06	4	39	2	10022829
Pubmed	Identification of a retinoid receptor response element in the human aldehyde dehydrogenase-2 promoter.	RARA RARB	7.34e-06	4	39	2	14691372
Pubmed	Retinoic acid regulates the human methionine sulfoxide reductase A (MSRA) gene via two distinct promoters.	RARA RARB	7.34e-06	4	39	2	18845237
Pubmed	The retinoic acid receptors RARalpha and RARgamma are required for inner ear development.	RARA RARB	7.34e-06	4	39	2	12464434
Pubmed	Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms.	RARA RARB	7.34e-06	4	39	2	9376317
Pubmed	Poly (ADP-ribose) glycohydrolase regulates retinoic acid receptor-mediated gene expression.	RARA RARB	7.34e-06	4	39	2	23102699
Pubmed	Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells.	RARA RARB	7.34e-06	4	39	2	9348290
Cytoband	19q13.4	PRKCG MZF1 ZNF416	4.29e-05	79	39	3	19q13.4
Cytoband	3q24	ZIC4 ZIC1	3.22e-04	31	39	2	3q24
Cytoband	Ensembl 112 genes in cytogenetic band chr3q24	ZIC4 ZIC1	7.42e-04	47	39	2	chr3q24
Cytoband	Ensembl 112 genes in cytogenetic band chr13q32	ZIC5 ZIC2	3.05e-03	96	39	2	chr13q32
Cytoband	Ensembl 112 genes in cytogenetic band chr3q27	CRYGS BCL6	5.34e-03	128	39	2	chr3q27
Cytoband	Xq28	ZFP92 ZNF275	9.87e-03	176	39	2	Xq28
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF462 ZNF74 ZIC4 ZFP42 ZFP92 ZNF275 ZNF497 BCL6 ZNF519 WIZ ZNF789 ZNF337 ZIC5 MZF1 ZNF416 CASZ1 ZIC1 ZIC2 YY2	4.24e-18	718	35	19	28
GeneFamily	Laminin subunits	LAMA2 LAMC3	2.37e-04	12	35	2	626
GeneFamily	Nuclear hormone receptors	RARA RARB	4.04e-03	49	35	2	71
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_100	LRP2 ZIC4 ZIC5 ZIC1 ZIC2	1.06e-06	100	39	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#2	ZIC4 ZIC5 PIK3CB ZIC1	1.32e-05	79	39	4	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500	ZNF462 LRP2 ZIC4 ZIC5 PIK3CB ZIC1 ZIC2	2.93e-05	496	39	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_100	LRP2 ZIC4 ZIC1 ZIC2	3.36e-05	100	39	4	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#3	ZNF462 ZIC4 PIK3CB ZIC1	4.54e-05	108	39	4	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#1_top-relative-expression-ranked_1000	LRP2 TJP2 ZFP42 CLXN PIK3CB	9.19e-05	251	39	5	gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000_k1
CoexpressionAtlas	ECTO blastocyst_vs_ECTO UCB CD34+Z-Confounder_removed-fold2.0_adjp0.05	COL11A2 FBN2 BCL6 ZIC5 ZIC2	1.64e-04	284	39	5	PCBC_ratio_ECTO blastocyst_vs_ECTO UCB CD34+Z_cfr-2X-p05
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#4_top-relative-expression-ranked_200	LRP2 ZFP42 CLXN	2.01e-04	62	39	3	gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_200_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#5	ZNF462 ZIC4 ZIC5 ZIC1	2.18e-04	162	39	4	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K5
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500	LRP2 ZIC4 ZFP42 COL11A2 ZIC1 ZIC2	2.42e-04	487	39	6	PCBC_ECTO_blastocyst_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	LRP2 ZIC4 ZIC5 PIK3CB ZIC1 ZIC2	2.73e-04	498	39	6	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2	LRP2 ZIC5 ZIC1	3.00e-04	71	39	3	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#1	ZIC4 ZIC5 PIK3CB ZIC1	3.06e-04	177	39	4	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000	ZNF462 LRP2 TJP2 ZIC4 ZIC5 PIK3CB ZIC1 ZIC2	3.58e-04	986	39	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	ZNF462 ZIC4 ZIC5 PIK3CB ZIC1	3.71e-04	339	39	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	ZNF462 ZIC4 PIK3CB ZIC1	4.50e-04	196	39	4	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5	LRP2 TJP2 ZIC5 ZIC1	5.33e-04	205	39	4	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_100	ZIC5 ZIC1 ZIC2	7.50e-04	97	39	3	Facebase_RNAseq_e8.5_Paraxial Mesoderm_100
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_100	LRP2 ZIC5 ZIC2	7.72e-04	98	39	3	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_100	LRP2 ZIC4 ZIC1	7.95e-04	99	39	3	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_100
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	LAMA2 ZIC4 LAMC3 CRYGS FBLN2 ZIC2	5.25e-09	159	39	6	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	metastatic_Brain-Fibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	LAMA2 ZIC4 LAMC3 FBLN2 RARB ZIC1	2.01e-08	199	39	6	63eb2106bb6e2e33d020628583536c8d96662c84
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ZIC4 LAMC3 CRYGS ZIC1 ZIC2	3.55e-07	168	39	5	26aa96b2b547d11941cb803995ea3d302ee0518c
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 LAMC3 ZIC5 ZIC1 ZIC2	3.55e-07	168	39	5	9930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 LAMC3 ZIC5 ZIC1 ZIC2	3.88e-07	171	39	5	2e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 LAMC3 ZIC5 ZIC1 ZIC2	3.88e-07	171	39	5	e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 FBLN2 ZIC1 ZIC2	4.73e-07	178	39	5	1802ff1c6cb18ee62cfef7270c0971048fae5315
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast-VLMC_L1-3_CYP1B1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 FBLN2 ZIC1 ZIC2	4.73e-07	178	39	5	4368d20130e5a08716564c19470b6014f16902ac
ToppCell	Posterior_cortex-Endothelial\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZIC4 LAMC3 ZIC5 ZIC1 ZIC2	7.42e-07	195	39	5	988e3449691cc228cb55e5e30355136c97b12262
ToppCell	metastatic_Brain-Fibroblasts-FB-like_cells\|metastatic_Brain / Location, Cell class and cell subclass	LAMA2 ZIC4 LAMC3 FBLN2 ZIC1	8.20e-07	199	39	5	12133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	ZIC4 CLXN ZIC5 ZIC1 ZIC2	8.41e-07	200	39	5	5fb90118d3abc28d72bc483e68317255090a04c7
ToppCell	Thalamus\|World / BrainAtlas - Mouse McCarroll V32	ZIC4 ZIC5 ZIC1 ZIC2	3.22e-06	116	39	4	5ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 LAMC3 ZIC1 ZIC2	7.18e-06	142	39	4	f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCell	Cerebellum\|World / BrainAtlas - Mouse McCarroll V32	ZIC4 ZIC5 ZIC1 ZIC2	8.23e-06	147	39	4	dd730224e39571ca2c35042e242a908a02ee377d
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA2 ZIC4 LAMC3 ZIC1	1.01e-05	155	39	4	d8b5145258f075b15080f8739f537f48dd22225e
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA2 ZIC4 LAMC3 ZIC1	1.01e-05	155	39	4	ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA2 ZIC4 LAMC3 ZIC1	1.01e-05	155	39	4	0f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 LAMC3 ZIC1 ZIC2	1.12e-05	159	39	4	34c90711c5857cf6ada7b3acff99f1d48c7caf29
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMC3 CRYGS FBN2 ZNF519	1.27e-05	164	39	4	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Control / Condition, Lineage and Cell class	LAMA2 FBN2 CASZ1 NAIP	1.36e-05	167	39	4	ab6029ba037b6a499da8758864c44e174cde5587
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Myeloid / Condition, Lineage and Cell class	LAMA2 FBN2 CASZ1 NAIP	1.36e-05	167	39	4	6e5140527437193f441ca96893b9a00d346614f3
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCSK MZF1 PIK3CB YY2	1.49e-05	171	39	4	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCSK MZF1 PIK3CB YY2	1.49e-05	171	39	4	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 LAMC3 ZIC1 ZIC2	1.60e-05	174	39	4	2891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 LAMC3 ZIC1 ZIC2	1.60e-05	174	39	4	eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 LAMC3 ZIC1 ZIC2	1.71e-05	177	39	4	599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 LAMC3 RARB BCL6	1.75e-05	178	39	4	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1 ZIC2	1.83e-05	180	39	4	f118c580134bdf3027e2218690cfc8a93468c1ae
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1 ZIC2	1.83e-05	180	39	4	1ade66352570a3f869e21e1055d0a65fbf56c61d
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes-Pericyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1 ZIC2	1.87e-05	181	39	4	634a4f4e5942473e60d08d0b0936407b04bc6b7c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1 ZIC2	1.87e-05	181	39	4	c2938cf1f5d4875be07a56a1f36c94f8eab37d99
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1 ZIC2	1.99e-05	184	39	4	9f524f0a1e7eb50e3b97a35c0ea7e183a4e99aa8
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ZIC4 CRYGS ZIC5 ZIC1	1.99e-05	184	39	4	235890e8b424f4386b6ea52d173d20a00898df73
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1 ZIC2	1.99e-05	184	39	4	779016341dbd6d54b5fdb8711692d31a9b2cec4b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Pericyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1 ZIC2	2.03e-05	185	39	4	0e26a71fea526ebfe3b2d1c8d0d6d9b70282bbe9
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1 ZIC2	2.03e-05	185	39	4	b3320b794b22e654a33f28b575c9f00023baf5f0
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 LAMA2 FBLN2 FBN2	2.12e-05	187	39	4	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 LAMA2 FBLN2 FBN2	2.12e-05	187	39	4	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 LAMA2 FBLN2 FBN2	2.12e-05	187	39	4	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	LAMA2 LAMC3 FBLN2 ZIC1	2.17e-05	188	39	4	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	(7)_DC_1\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ZNF462 TJP2 BCL6 PIK3CB	2.17e-05	188	39	4	832887afa4a54ed80906bc02176d646529c13398
ToppCell	Hippocampus-Endothelial\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ZIC4 LAMC3 ZIC1 ZIC2	2.35e-05	192	39	4	36deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 LAMC3 RARB BCL6	2.40e-05	193	39	4	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 LAMC3 RARB BCL6	2.40e-05	193	39	4	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	metastatic_Brain-Fibroblasts-Pericytes\|metastatic_Brain / Location, Cell class and cell subclass	LAMA2 LAMC3 RARB ZIC1	2.45e-05	194	39	4	d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 LAMC3 RARB BCL6	2.60e-05	197	39	4	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMA2 ZIC4 LAMC3 FBLN2	2.71e-05	199	39	4	dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMA2 ZIC4 LAMC3 FBLN2	2.71e-05	199	39	4	c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuroepithelial\|1m / Sample Type, Dataset, Time_group, and Cell type.	LAMA2 ZIC4 FBLN2 YY2	2.76e-05	200	39	4	fe15fb050852c187f6f17fb4f6172e69fe7d74a4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuroepithelial-Proteoglycan-expressing_cell\|1m / Sample Type, Dataset, Time_group, and Cell type.	LAMA2 ZIC4 FBLN2 YY2	2.76e-05	200	39	4	d0a4c3bf9c5211defb4c1d0b6653833cccbd29ee
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	ZNF497 ZNF337 CASZ1	1.29e-04	112	39	3	518b7ab98b988b23f3d0f0e1f4fe90a7068f9d87
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZIC4 ZIC1 ZIC2	1.70e-04	123	39	3	64a2d7e40d9c948a9ccaf61c465fb2207e0b7ab8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZIC4 FBN2 BCL6	1.91e-04	128	39	3	076ba9de63b9a4b5a2f7e7924b9a86e8eafce91f
ToppCell	COVID-19-kidney-Mito-rich_Int\|kidney / Disease (COVID-19 only), tissue and cell type	LAMA2 ZIC4 LAMC3	1.95e-04	129	39	3	57b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	LAMA2 LAMC3 FBN2	2.23e-04	135	39	3	5b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Monophasic_Synovial_Sarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	COL11A2 ZIC5 ZIC2	2.33e-04	137	39	3	576ca865b8e8e59d23aa35cb9dafee0cf7d38e6a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRKCG BCL6 CASZ1	2.48e-04	140	39	3	7cc891d676555609add6fc7880735d948a2ad801
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RARB BCL6 CASZ1	2.54e-04	141	39	3	40ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	LAMA2 TJP2 CLXN	3.10e-04	151	39	3	4533bccc996395f74b16af939ce79b6fe253c073
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	LAMA2 TJP2 CLXN	3.10e-04	151	39	3	edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	LAMC3 CRYGS FBLN2	3.22e-04	153	39	3	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	LAMC3 CRYGS FBLN2	3.22e-04	153	39	3	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	LAMC3 CRYGS FBLN2	3.22e-04	153	39	3	2513edfae62a44e51d3556675a096723194c966c
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|368C / Donor, Lineage, Cell class and subclass (all cells)	LRP2 FBN2 CASZ1	3.41e-04	156	39	3	25b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMC3 FBN2 RARB	3.47e-04	157	39	3	beab0ac47202266b04543c02cfcdda012375e879
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 LAMA2 FBN2	3.67e-04	160	39	3	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 LAMA2 FBN2	3.67e-04	160	39	3	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-5_LINC00507_SLN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA2 RARB CLXN	3.81e-04	162	39	3	b59a0081e285cdf33de56e8b523fe0e446a198f1
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	ZFP42 CRYGS FBN2	3.95e-04	164	39	3	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_early_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	ZIC4 ZIC1 ZIC2	4.02e-04	165	39	3	e460e03992781073cd836a655f15dda3157cea55
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TJP2 FBLN2 ZNF789	4.23e-04	168	39	3	968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCell	facs-Tongue-nan-3m-Epithelial-basal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP42 BCL6 MOG	4.23e-04	168	39	3	ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 LAMC3 ZNF519	4.23e-04	168	39	3	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LAMC3 RARB	4.53e-04	172	39	3	de4961f4037c439d3e0ec706a257b0ec17f4d5be
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 TJP2 LAMC3	4.61e-04	173	39	3	ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCell	Substantia_nigra-Macroglia\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TJP2 COL11A2 MOG	4.69e-04	174	39	3	7e7f7ca9a413ec255e54621800a279c771b9e6b7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZFP42 FBN2 BCL6	4.69e-04	174	39	3	46bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell	Posterior_cortex-Macroglia\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TJP2 COL11A2 MOG	4.77e-04	175	39	3	8bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL6 PIK3CB CASZ1	4.77e-04	175	39	3	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL11A2 FBN2 CLXN	5.01e-04	178	39	3	8591a40fced747ac16b3e8ebc7a22dfb3ad76da2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 LAMC3 ZIC1	5.09e-04	179	39	3	f99500c4a590e5152ded5862690f7fa614d64a80
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1	5.09e-04	179	39	3	368f7e91e9c2c854c8778788cead022d158d1122
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 LAMC3 ZIC1	5.09e-04	179	39	3	7d61466181ab73088de3ec8a129d7cfa8cac7ecc
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1	5.09e-04	179	39	3	11e434fc49bc0a806197f21debcac8337e0502aa
ToppCell	Entopeduncular-Macroglia\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TJP2 COL11A2 MOG	5.09e-04	179	39	3	f61974710a60aa0618fdb30d864fb9bc7c05ef21
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 LAMC3 ZIC1	5.09e-04	179	39	3	6c98ce32cb55cf9cee557449e41b23bdb22f5efd
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 ZIC4 FBLN2	5.18e-04	180	39	3	39ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMA2 LAMC3 ZIC1	5.18e-04	180	39	3	64956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCell	Thalamus-Macroglia\|Thalamus / BrainAtlas - Mouse McCarroll V32	TJP2 COL11A2 MOG	5.26e-04	181	39	3	4f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF74 ZFP42 ZNF337	5.26e-04	181	39	3	c1fad1f03468523e563c039be520dcf7717f90cd
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 ZFP92 ZIC2	5.26e-04	181	39	3	6d1f1ad35778a2a227f966f11f6edd8e89452576
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 ZFP92 CLXN	5.35e-04	182	39	3	587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 ZFP92 CLXN	5.35e-04	182	39	3	adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	LAMA2 LAMC3 FBN2	5.35e-04	182	39	3	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMA2 LAMC3 ZIC1	5.35e-04	182	39	3	fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1	5.43e-04	183	39	3	944f7458b9127356815f75c88bbf7015ebdc8ec1
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMA2 LAMC3 FBN2	5.43e-04	183	39	3	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes-Pericyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZIC4 LAMC3 ZIC1	5.43e-04	183	39	3	cee6b821adff538078232689965d3e6c131e7d14
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 LAMC3 FBLN2	5.43e-04	183	39	3	ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCell	facs-Bladder-nan-18m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMC3 BCL6 MOG	5.61e-04	185	39	3	3e00879466e626aa8604efecfc4678d64f54dbfc
Drug	Ro 8-8717	RARA RARB	2.86e-06	2	39	2	CID006438148
Drug	Tamibarotene	RARA RARB	2.86e-06	2	39	2	DB04942
Drug	AC1L1B58	LAMA2 PRKCG LAMC3	1.65e-05	29	39	3	CID000001288
Drug	SRI 5898-21	RARA RARB	1.71e-05	4	39	2	CID006439757
Drug	Tazarotene	RARA RARB	1.71e-05	4	39	2	DB00799
Drug	Cd2366	RARA RARB	2.85e-05	5	39	2	CID006443796
Drug	Alitretinoin	RARA RARB	4.27e-05	6	39	2	DB00523
Drug	Adapalene	RARA RARB	4.27e-05	6	39	2	DB00210
Drug	Etretinate	RARA RARB	4.27e-05	6	39	2	DB00926
Drug	4-oxoretinoic acid	LAMA2 LAMC3 RARA RARB	4.43e-05	115	39	4	ctd:C002202
Drug	Acitretin	RARA RARB	5.97e-05	7	39	2	DB00459
Drug	HX 600	RARA RARB	7.95e-05	8	39	2	ctd:C104181
Drug	2-naphthoic acid	RARA RARB	7.95e-05	8	39	2	CID000007123
Drug	4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid	RARA RARB	7.95e-05	8	39	2	ctd:C064545
Drug	Adapalene	RARA RARB	7.95e-05	8	39	2	ctd:D000068816
Drug	TTNN	RARA RARB	7.95e-05	8	39	2	CID000135754
Drug	4-((4-(4-ethylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl)ethynyl)benzoic acid	RARA RARB	7.95e-05	8	39	2	ctd:C121616
Drug	retinyl methyl ether	RARA RARB	1.02e-04	9	39	2	CID006436634
Drug	HX 630	RARA RARB	1.28e-04	10	39	2	ctd:C422175
Drug	CEPC	RARA RARB	1.28e-04	10	39	2	CID000011483
Drug	AC1L1KMJ	LAMA2 TJP2 PRKCG LAMC3 COL11A2 PIK3CB	1.47e-04	476	39	6	CID000030956
Drug	AC1L1G72	LAMA2 LAMC3	1.56e-04	11	39	2	CID000003553
Drug	UVI 3003	RARA RARB	1.56e-04	11	39	2	ctd:C525131
Drug	alpha-CaM	PRKCG ZIC1 ZIC2	1.64e-04	62	39	3	CID000196705
Disease	Dandy-Walker syndrome (implicated_via_orthology)	ZIC4 ZIC1	4.10e-06	3	35	2	DOID:2785 (implicated_via_orthology)
Disease	Neuralgia-Neuritis, Sciatic Nerve	RARA RARB	8.19e-06	4	35	2	C0751924
Disease	Sciatic Nerve Palsy	RARA RARB	8.19e-06	4	35	2	C0751925
Disease	Lesion of Sciatic Nerve	RARA RARB	8.19e-06	4	35	2	C0154748
Disease	Sciatic Neuritis	RARA RARB	8.19e-06	4	35	2	C0242013
Disease	Sciatic Neuropathy	RARA RARB	8.19e-06	4	35	2	C0149940
Disease	pulmonary function measurement, smoking behaviour measurement, FEV/FEC ratio	RARB BCL6 MOG	2.39e-05	47	35	3	EFO_0003892, EFO_0004713, EFO_0005671
Disease	migraine disorder	ZNF462 TJP2 FBN2 CASZ1 MOG	6.07e-05	357	35	5	MONDO_0005277
Disease	octadecanedioate measurement	LAMA2 LAMC3	6.11e-05	10	35	2	EFO_0021056
Disease	Schizophrenia	LRP2 LAMA2 ZNF74 RARA PIK3CB MOG ZIC2	6.78e-05	883	35	7	C0036341
Disease	Sensory hearing loss	LRP2 COL11A2	7.47e-05	11	35	2	C1691779
Disease	body surface area	ZNF462 FBLN2 FBN2 RARB BCL6 ZIC1	9.91e-05	643	35	6	EFO_0022196
Disease	Proteinuria	LRP2 RARB	1.42e-04	15	35	2	HP_0000093
Disease	Craniosynostosis	ZNF462 ZIC1	2.56e-04	20	35	2	C0010278
Disease	cortical thickness, neuroimaging measurement	ZIC4 LAMC3 MOG	3.02e-04	110	35	3	EFO_0004346, EFO_0004840
Disease	Sensorineural Hearing Loss (disorder)	LRP2 COL11A2	3.40e-04	23	35	2	C0018784
Disease	Iniencephaly	ZIC5 ZIC2	5.07e-04	28	35	2	C0152234
Disease	Tethered Cord Syndrome	ZIC5 ZIC2	5.07e-04	28	35	2	C0080218
Disease	Spinal Cord Myelodysplasia	ZIC5 ZIC2	5.07e-04	28	35	2	C0344479
Disease	Exencephaly	ZIC5 ZIC2	5.07e-04	28	35	2	C0266453
Disease	Neurenteric Cyst	ZIC5 ZIC2	5.07e-04	28	35	2	C0027806
Disease	Acrania	ZIC5 ZIC2	5.07e-04	28	35	2	C0702169
Disease	Diastematomyelia	ZIC5 ZIC2	5.07e-04	28	35	2	C0011999
Disease	Craniorachischisis	ZIC5 ZIC2	5.44e-04	29	35	2	C0152426
Disease	Neural Tube Defects	ZIC5 ZIC2	5.82e-04	30	35	2	C0027794
Disease	cataract	RARB HERC2 CASZ1	6.25e-04	141	35	3	MONDO_0005129
Disease	Head and Neck Neoplasms	RARB PIK3CB	7.05e-04	33	35	2	C0018671
Disease	refractive error, self reported educational attainment	LAMA2 TJP2	7.49e-04	34	35	2	EFO_0004784, MONDO_0004892
Disease	Prostatic Neoplasms	LRP2 NAGK PIK3CB CASZ1 ZIC2	7.54e-04	616	35	5	C0033578
Disease	Malignant neoplasm of prostate	LRP2 NAGK PIK3CB CASZ1 ZIC2	7.54e-04	616	35	5	C0376358
Disease	Craniofacial Abnormalities	LRP2 COL11A2 ZIC5	8.38e-04	156	35	3	C0376634
Disease	age at first sexual intercourse measurement	ZIC4 RARB ZNF789 ZIC1	1.06e-03	383	35	4	EFO_0009749
Disease	Neoplasm of uncertain or unknown behavior of breast	HERC2 PIK3CB	1.09e-03	41	35	2	C0496956
Disease	Breast adenocarcinoma	HERC2 PIK3CB	1.09e-03	41	35	2	C0858252

Protein segments in the cluster

Peptide	Gene	Start	Entry
ALKGFFSCCFEFNDD	NAIP	696	Q13075
RRFGTKDFCDGQCDF	CASZ1	1011	Q86V15
CRFAGFCRKIAEGAQ	NAGK	211	Q9UJ70
ENFRQFCTGEFRKDG	PPIH	41	O43447
GVSACEGCKGFFRRS	RARA	101	P10276
GVSACEGCKGFFRRS	RARB	101	P10826
FEKSARRDGARCGFE	GIGYF1	166	O75420
INGSRFKCRNCDDFD	HERC2	2716	O95714
CKAGFQRDAFGRGCI	FBLN2	886	P98095
RDAFRVFCNFTAGGE	COL11A2	1596	P13942
NVEGGDCSRCKSGFF	LAMA2	491	P24043
CGRSGENFDKFFTRA	PRKCG	636	P05129
DNDGLGFRCKCTFGF	LRP2	681	P98164
GFRCKCTFGFQLDTD	LRP2	686	P98164
NVRFSDEGGFTCFFR	MOG	116	Q16653
GRDFPFDDCGRAFTC	FCSK	96	Q8N0W3
FQGRRYDCDCDCADF	CRYGS	16	P22914
GAFFCNECDCRFSEE	BCL6	516	P41182
DNGRRCFDTRQSFCF	FBN2	2091	P35556
RDIRCEFCGEFFENR	WIZ	1041	O95785
DIRCEFCGEFFENRK	WIZ	1226	O95785
TEKFGRFRQCCEDAY	PIK3CB	976	P42338
RVFRGFDKDNDGCVN	CLXN	71	Q9HAE3
FACGDCGKLFRRSFA	ZFP92	236	A6NM28
ERPFACAECGKAFRG	ZNF497	411	Q6ZNH5
CGRGDSFFIRSHFEC	TJP2	601	Q9UDY2
RAFKCEECGKAFNRG	ZNF519	346	Q8TB69
FQCTFEGCGKRFSLD	YY2	311	O15391
RCTFEGCGKRFSLDF	ZFP42	246	Q96MM3
EKPFRCEFEGCERRF	ZIC4	231	Q8N9L1
PFKCEFEGCDRRFAN	ZIC1	331	Q15915
RPFECDECGKSFSQR	ZNF416	436	Q9BWM5
ERPFECSECGKFFRQ	ZNF416	491	Q9BWM5
EKRFPCEFCGRAFSQ	ZNF462	2411	Q96JM2
GEFVCGECGKAFRQS	ZNF74	246	Q16587
CGDCGKVFRGVAEFN	ZNF275	131	Q9NSD4
EEFFQCGECGKTFSF	ZNF789	366	Q5FWF6
KPFQCEFEGCDRRFA	ZIC2	361	O95409
LGEKRFFCRDCGRGF	ZNF337	511	Q9Y3M9
FKCEFDGCDRKFANS	ZIC5	521	Q96T25
QRGRRCEVCDDGFFG	LAMC3	781	Q9Y6N6
KSFGCVECGERFGRR	MZF1	511	P28698