Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

1.15e-044882GO:0005219
GeneOntologyMolecularFunctiondeaminase binding

HNRNPCL1 HNRNPCL2

1.15e-044882GO:1990827
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

2.85e-046882GO:0048763
GeneOntologyMolecularFunctionribonucleoprotein complex binding

HNRNPCL1 NOMO2 NEMF NOMO3 HNRNPCL2 NOMO1

3.01e-04206886GO:0043021
GeneOntologyMolecularFunctionactin filament binding

TPM1 TPM2 TPM3 TPM4 MICAL1 RCSD1

5.04e-04227886GO:0051015
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1B CACNA2D1 ATP2B3 RYR2 RYR3

5.47e-04151885GO:0015085
GeneOntologyMolecularFunctiongated channel activity

CACNA1B CACNA2D1 PIEZO2 KCNA4 ANXA6 RYR2 RYR3

6.85e-04334887GO:0022836
GeneOntologyMolecularFunctionangiotensin receptor binding

ARRB1 ZBTB16

8.44e-0410882GO:0031701
GeneOntologyMolecularFunctionstructural constituent of muscle

TPM1 TPM2 TPM4

8.99e-0443883GO:0008307
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1B CACNA2D1 SLC4A8 KCNA4 SLC20A2 ATP2B3 RYR2 RYR3

1.03e-03465888GO:0046873
GeneOntologyBiologicalProcessmuscle contraction

TPM1 TPM2 TPM3 TPM4 CACNA2D1 ANXA6 LMOD1 RCSD1 UTY RYR2 RYR3

8.45e-074008611GO:0006936
GeneOntologyBiologicalProcessmuscle system process

TPM1 TPM2 TPM3 TPM4 CACNA2D1 ANXA6 LMOD1 COL14A1 RCSD1 UTY RYR2 RYR3

2.75e-065478612GO:0003012
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO2 NOMO3 NOMO1

5.77e-069863GO:0160063
GeneOntologyBiologicalProcessmuscle structure development

TPM1 LUC7L FLOT2 ZEB1 NKD1 TLL2 LAMA2 SHOX2 LMOD1 COL14A1 ACTL6A CAMK1 RYR2

5.34e-058588613GO:0061061
GeneOntologyBiologicalProcesspositive regulation of neurotransmitter secretion

CACNA1B SLC4A8 STXBP1

1.51e-0425863GO:0001956
GeneOntologyBiologicalProcessheart contraction

TPM1 CACNA1B CACNA2D1 SHOX2 UTY ATP2B3 RYR2

2.48e-04298867GO:0060047
GeneOntologyBiologicalProcessnegative regulation of mRNA modification

HNRNPCL1 HNRNPCL2

2.55e-046862GO:0090367
GeneOntologyBiologicalProcessprotein insertion into ER membrane

NOMO2 NOMO3 NOMO1

2.89e-0431863GO:0045048
GeneOntologyBiologicalProcessstriated muscle contraction

TPM1 CACNA2D1 RCSD1 UTY RYR2 RYR3

2.95e-04217866GO:0006941
GeneOntologyBiologicalProcessheart process

TPM1 CACNA1B CACNA2D1 SHOX2 UTY ATP2B3 RYR2

3.09e-04309867GO:0003015
GeneOntologyBiologicalProcesspositive regulation of neurotransmitter transport

CACNA1B SLC4A8 STXBP1

3.18e-0432863GO:0051590
GeneOntologyBiologicalProcesspattern specification process

CLUAP1 ZEB1 ZBTB16 NKD1 TLL2 DNAI2 ODAD4 NOMO3 NOMO1

3.43e-04526869GO:0007389
GeneOntologyBiologicalProcessregulation of mRNA modification

HNRNPCL1 HNRNPCL2

3.56e-047862GO:0090365
GeneOntologyBiologicalProcessribosome-associated ubiquitin-dependent protein catabolic process

NEMF ASCC3

3.56e-047862GO:1990116
GeneOntologyBiologicalProcessnegative regulation of nodal signaling pathway

NOMO3 NOMO1

3.56e-047862GO:1900108
GeneOntologyCellularComponentmuscle thin filament tropomyosin

TPM1 TPM2 TPM3 TPM4

2.93e-104884GO:0005862
GeneOntologyCellularComponentstriated muscle thin filament

TPM1 TPM2 TPM3 TPM4 LMOD1

8.84e-0827885GO:0005865
GeneOntologyCellularComponentmyofilament

TPM1 TPM2 TPM3 TPM4 LMOD1

2.17e-0732885GO:0036379
GeneOntologyCellularComponentactin filament

TPM1 TPM2 TPM3 TPM4 MICAL1 LMOD1 RCSD1

2.78e-06146887GO:0005884
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO2 NOMO3 NOMO1

5.95e-069883GO:0160064
GeneOntologyCellularComponentpresynaptic membrane

CACNA2D1 FLOT2 SLC4A8 KCNA4 STXBP1 PTPRD EXOC3 ATP2B3

2.21e-05277888GO:0042734
GeneOntologyCellularComponentER membrane insertion complex

NOMO2 NOMO3 NOMO1

2.54e-0514883GO:0072379
GeneOntologyCellularComponentsarcomere

TPM1 TPM2 TPM3 TPM4 LMOD1 RYR2 RYR3

8.74e-05249887GO:0030017
GeneOntologyCellularComponentactin cytoskeleton

TPM1 TPM2 TPM3 TPM4 MICAL1 FLOT2 HNRNPCL1 LMOD1 RCSD1 HNRNPCL2

1.53e-045768810GO:0015629
GeneOntologyCellularComponentmyofibril

TPM1 TPM2 TPM3 TPM4 LMOD1 RYR2 RYR3

1.55e-04273887GO:0030016
GeneOntologyCellularComponentsynaptic membrane

CACNA2D1 FLOT2 ARRB1 SLC4A8 KCNA4 STXBP1 PTPRD EXOC3 NBEA ATP2B3

1.69e-045838810GO:0097060
GeneOntologyCellularComponentpronucleus

HNRNPCL1 TET3 HNRNPCL2

2.19e-0428883GO:0045120
GeneOntologyCellularComponentcontractile muscle fiber

TPM1 TPM2 TPM3 TPM4 LMOD1 RYR2 RYR3

2.24e-04290887GO:0043292
GeneOntologyCellularComponentcalcium channel complex

CACNA1B CACNA2D1 RYR2 RYR3

2.56e-0473884GO:0034704
GeneOntologyCellularComponentnucleoplasmic periphery of the nuclear pore complex

HNRNPCL1 HNRNPCL2

2.60e-046882GO:1990826
GeneOntologyCellularComponenthippocampal mossy fiber

MICAL1 SLC4A8

3.63e-047882GO:0097457
GeneOntologyCellularComponentsarcolemma

CACNA2D1 ANXA6 LAMA2 RYR2 RYR3

1.25e-03190885GO:0042383
GeneOntologyCellularComponentsupramolecular fiber

TPM1 TPM2 TPM3 CEP170 TPM4 MICAL1 DNAL4 KRT78 DNAI2 LMOD1 RCSD1 RYR2 RYR3

1.27e-0311798813GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

TPM1 TPM2 TPM3 CEP170 TPM4 MICAL1 DNAL4 KRT78 DNAI2 LMOD1 RCSD1 RYR2 RYR3

1.35e-0311878813GO:0099081
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

TPM1 TPM2 TPM3 CEP170 TPM4 MICAL1 DNAL4 KRT78 DNAI2 LMOD1 RCSD1

1.36e-038998811GO:0099513
GeneOntologyCellularComponentspliceosomal complex

PPP1R8 LUC7L HNRNPCL1 NCL HNRNPCL2

2.16e-03215885GO:0005681
GeneOntologyCellularComponentglutamatergic synapse

CACNA1B CACNA2D1 FLOT2 SLC4A8 KCNA4 STXBP1 PTPRD NBEA CAMK1 ATP2B3

2.26e-038178810GO:0098978
GeneOntologyCellularComponentpresynaptic active zone

CACNA1B CACNA2D1 FLOT2 STXBP1

2.98e-03141884GO:0048786
GeneOntologyCellularComponentcation channel complex

CACNA1B CACNA2D1 KCNA4 RYR2 RYR3

3.16e-03235885GO:0034703
DomainTROPOMYOSIN

TPM1 TPM2 TPM3 TPM4

4.19e-104864PS00326
DomainTropomyosin

TPM1 TPM2 TPM3 TPM4

4.19e-104864IPR000533
DomainTropomyosin

TPM1 TPM2 TPM3 TPM4

4.19e-104864PF00261
DomainDUF2012

NOMO2 NOMO3 NOMO1

3.76e-074863PF09430
DomainDUF2012

NOMO2 NOMO3 NOMO1

3.76e-074863IPR019008
DomainCarb-bd-like_fold

NOMO2 NOMO3 NOMO1

5.19e-068863IPR013784
DomainCarboxyPept_regulatory_dom

NOMO2 NOMO3 NOMO1

2.61e-0513863IPR014766
Domain-

NOMO2 NOMO3 NOMO1

2.61e-05138632.60.40.1120
DomainCarboxyPept-like_regulatory

NOMO2 NOMO3 NOMO1

6.12e-0517863IPR008969
DomainRyanrecept_TM4-6

RYR2 RYR3

6.27e-053862IPR009460
DomainRyR

RYR2 RYR3

6.27e-053862PF02026
DomainRyanodine_rcpt

RYR2 RYR3

6.27e-053862IPR003032
DomainRR_TM4-6

RYR2 RYR3

6.27e-053862PF06459
DomainRyan_recept

RYR2 RYR3

6.27e-053862IPR013333
DomainFHA

CEP170 PPP1R8 CHFR

2.84e-0428863SM00240
DomainRIH_assoc

RYR2 RYR3

3.11e-046862PF08454
DomainRIH_assoc-dom

RYR2 RYR3

3.11e-046862IPR013662
DomainRIH_dom

RYR2 RYR3

3.11e-046862IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

3.11e-046862IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

3.11e-046862IPR015925
Domain-

RYR2 RYR3

3.11e-0468621.25.10.30
DomainhnRNP_C

HNRNPCL1 HNRNPCL2

3.11e-046862IPR017347
DomainRYDR_ITPR

RYR2 RYR3

3.11e-046862PF01365
DomainIns145_P3_rec

RYR2 RYR3

3.11e-046862PF08709
DomainTPR

NASP ODAD4 IFIT2 ANAPC5 UTY

3.24e-04129865SM00028
DomainTPR_repeat

NASP ODAD4 IFIT2 ANAPC5 UTY

3.73e-04133865IPR019734
DomainFHA_DOMAIN

CEP170 PPP1R8 CHFR

3.86e-0431863PS50006
DomainFHA

CEP170 PPP1R8 CHFR

3.86e-0431863PF00498
DomainFHA_dom

CEP170 PPP1R8 CHFR

6.03e-0436863IPR000253
Domain-

CEP170 PPP1R8 CHFR

6.03e-04368632.60.200.20
DomainTPR-contain_dom

NASP ODAD4 IFIT2 ANAPC5 UTY

6.45e-04150865IPR013026
DomainMIR

RYR2 RYR3

9.21e-0410862PS50919
DomainMIR

RYR2 RYR3

9.21e-0410862PF02815
DomainMIR

RYR2 RYR3

9.21e-0410862SM00472
DomainMIR_motif

RYR2 RYR3

9.21e-0410862IPR016093
DomainTPR_REGION

NASP ODAD4 IFIT2 ANAPC5 UTY

9.91e-04165865PS50293
DomainTPR

NASP ODAD4 IFIT2 ANAPC5 UTY

9.91e-04165865PS50005
DomainSMAD_FHA_domain

CEP170 PPP1R8 CHFR

1.77e-0352863IPR008984
DomainTPR_8

ODAD4 IFIT2 UTY

1.87e-0353863PF13181
DomainIon_trans_dom

CACNA1B KCNA4 RYR2 RYR3

1.90e-03114864IPR005821
DomainIon_trans

CACNA1B KCNA4 RYR2 RYR3

1.90e-03114864PF00520
Domain-

NASP ODAD4 IFIT2 ANAPC5 UTY

2.68e-032078651.25.40.10
DomainConA-like_dom

LAMA2 COL14A1 NBEA RYR2 RYR3

3.42e-03219865IPR013320
Domain-

CFAP251 DNAI2 WDR55 NBEA BIRC6 BRWD3

4.37e-033338662.130.10.10
DomainTPR-like_helical_dom

NASP ODAD4 IFIT2 ANAPC5 UTY

4.44e-03233865IPR011990
DomainWD40/YVTN_repeat-like_dom

CFAP251 DNAI2 WDR55 NBEA BIRC6 BRWD3

4.50e-03335866IPR015943
PathwayREACTOME_SMOOTH_MUSCLE_CONTRACTION

TPM1 TPM2 TPM3 TPM4 ANXA6 LMOD1

3.68e-0843646M1429
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

TPM1 TPM2 TPM3 TPM4 CACNA2D1 LAMA2 RYR2

8.99e-0883647M8728
PathwayKEGG_DILATED_CARDIOMYOPATHY

TPM1 TPM2 TPM3 TPM4 CACNA2D1 LAMA2 RYR2

1.58e-0790647M835
PathwayREACTOME_MUSCLE_CONTRACTION

TPM1 TPM2 TPM3 TPM4 ANXA6 LMOD1 ATP2B3 RYR2 RYR3

3.10e-07203649M5485
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1B ARRB1 ANXA6 CAMK1 ATP2B3 RYR2 RYR3 SFN

3.12e-07147648MM15854
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1B ARRB1 ANXA6 CAMK1 ATP2B3 RYR2 RYR3 SFN

3.83e-07151648M39329
PathwayREACTOME_SMOOTH_MUSCLE_CONTRACTION

TPM1 TPM2 TPM3 TPM4 LMOD1

4.81e-0735645MM15114
PathwayREACTOME_MUSCLE_CONTRACTION

TPM1 TPM2 TPM3 TPM4 LMOD1 ATP2B3 RYR2 RYR3

7.54e-07165648MM15026
PathwayKEGG_CARDIAC_MUSCLE_CONTRACTION

TPM1 TPM2 TPM3 TPM4 CACNA2D1 RYR2

1.48e-0679646M17673
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1B RYR2 RYR3

1.43e-0511643M47958
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

TPM1 TPM2 TPM3 TPM4

1.82e-0535644MM15005
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

TPM1 TPM2 TPM3 TPM4

2.04e-0536644M18647
PathwayWP_STRIATED_MUSCLE_CONTRACTION_PATHWAY

TPM1 TPM2 TPM3 TPM4

2.54e-0538644M39549
Pubmed

A systematic nomenclature for mammalian tropomyosin isoforms.

TPM1 TPM2 TPM3 TPM4

3.83e-11488425369766
Pubmed

Tropomyosin isoforms localize to distinct microfilament populations in osteoclasts.

TPM1 TPM2 TPM3 TPM4

3.83e-11488416765662
Pubmed

Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer.

TPM1 TPM2 TPM3 TPM4

5.72e-10688423792823
Pubmed

Smooth muscle contraction and relaxation.

TPM1 TPM2 TPM3 TPM4 LMOD1

2.35e-092288514627618
Pubmed

Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.

TPM3 FLOT2 HNRNPCL1 PA2G4 L1TD1 ZNF638 NASP NCL HNRNPCL2 SFN

1.28e-08332881030595499
Pubmed

Vertebrate tropomyosin: distribution, properties and function.

TPM1 TPM2 TPM3

1.57e-08388311563548
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO2 NOMO3 NOMO1

1.57e-08388336011023
Pubmed

Specificity of dimer formation in tropomyosins: influence of alternatively spliced exons on homodimer and heterodimer assembly.

TPM1 TPM2 TPM3

1.57e-0838837568216
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO2 NOMO3 NOMO1

1.57e-08388325576386
Pubmed

A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism.

TPM2 TPM3 TPM4

1.57e-0838833865200
Pubmed

Ca2+-dependent interaction of S100A2 with muscle and nonmuscle tropomyosins.

TPM1 TPM2 TPM3

6.25e-0848839092943
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO2 NOMO3 NOMO1

6.25e-08488331833031
Pubmed

Degradation of cytoskeletal proteins by the human immunodeficiency virus type 1 protease.

TPM1 TPM2 TPM3

6.25e-0848831516138
Pubmed

Actin and tropomyosin isoforms in morphogenesis.

TPM1 TPM2 TPM3

6.25e-0848839108196
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO2 NOMO3 NOMO1

6.25e-0848839267806
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

TPM1 TPM2 TPM3 NOMO2 ACTL6A NOMO3 NOMO1

1.49e-0715688730409884
Pubmed

DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.

TPM1 TPM2 TPM3 TPM4 KRT78 NCL UTY SFN

1.72e-0723888835864588
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

TPM1 TPM2 TPM3 CEP170 LUC7L NEMF EXOC3 NCL ACTL6A ASCC3 SFN

3.60e-07601881133658012
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

TPM1 TPM3 CEP170 TPM4 LUC7L L1TD1 NCL BIRC6

4.35e-0726988829511261
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

TPM1 TPM2 TPM3 CEP170 LUC7L ZBTB16 ZBTB40 LAMA2 COL14A1 BIRC6

5.41e-07497881023414517
Pubmed

Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice.

TPM1 TPM2 TPM4

5.44e-07788319118250
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO2 NOMO3 NOMO1

8.69e-07888315257293
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO2 NOMO3 NOMO1

1.30e-06988336261522
Pubmed

Ligand-dependent differences in estrogen receptor beta-interacting proteins identified in lung adenocarcinoma cells corresponds to estrogenic responses.

TPM1 TPM3 TPM4 NCL

1.30e-063288421951318
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

TPM1 TPM2 TPM3 TPM4 FLOT2 PA2G4 ANXA6 NASP BOD1L1 NCL ACTL6A SFN

1.52e-06847881235235311
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO2 NOMO3 NOMO1

2.55e-061188332820719
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1B ATP2B3 RYR2 RYR3

2.64e-063888430786075
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

HNRNPCL1 NOMO2 PA2G4 NCL BIRC6 NOMO3 HNRNPCL2 NOMO1

2.73e-0634488830333137
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

TPM1 TPM2 TPM3 TPM4 HNRNPCL1 ARRB1 STXBP1 ABCB5 BOD1L1 NCL ATP2B3 HNRNPCL2 RYR2 ZNF541 SFN

3.15e-061442881535575683
Pubmed

Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia.

TPM1 TPM2 TPM3 TPM4

3.26e-064088420381070
Pubmed

Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.

TPM1 TPM2 TPM3

3.39e-06128838424456
Pubmed

HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.

TPM1 TPM2 TPM3 TPM4

3.61e-064188424614889
Pubmed

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.

TPM1 TPM2 TPM3 TPM4 RHBDL2 NCL ACTL6A

4.45e-0625988731162944
Pubmed

Isolation and characterization of a cDNA that encodes mouse fibroblast tropomyosin isoform 2.

TPM1 TPM2

6.33e-0628823244365
Pubmed

Structural and functional properties of αβ-heterodimers of tropomyosin with myopathic mutations Q147P and K49del in the β-chain.

TPM1 TPM2

6.33e-06288230545627
Pubmed

High molecular weight tropomyosins regulate osteoclast cytoskeletal morphology.

TPM2 TPM3

6.33e-06288218674650
Pubmed

Inflammatory Adipokines Decrease Expression of Two High Molecular Weight Isoforms of Tropomyosin Similar to the Change in Type 2 Diabetic Patients.

TPM1 TPM4

6.33e-06288227649540
Pubmed

PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.

ZBTB16 IFIT2

6.33e-06288229358655
Pubmed

MLL4 binds TET3.

KMT2B TET3

6.33e-06288238579707
Pubmed

Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits.

CACNA1B CACNA2D1

6.33e-06288224889613
Pubmed

ABCB5-ZEB1 Axis Promotes Invasion and Metastasis in Breast Cancer Cells.

ZEB1 ABCB5

6.33e-06288228281973
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

6.33e-06288221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

6.33e-06288216678258
Pubmed

Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms.

TPM2 TPM3

6.33e-06288222798622
Pubmed

Changes in end-to-end interactions of tropomyosin affect mouse cardiac muscle dynamics.

TPM1 TPM2

6.33e-06288216501024
Pubmed

Variants in tropomyosins TPM2 and TPM3 causing muscle hypertonia.

TPM2 TPM3

6.33e-06288238219297
Pubmed

Functional structure of the promoter regions for the predominant low molecular weight isoforms of tropomyosin in human kidney cells.

TPM1 TPM3

6.33e-06288222740512
Pubmed

Frequency and phenotype of patients carrying TPM2 and TPM3 gene mutations in a cohort of 94 patients with congenital myopathy.

TPM2 TPM3

6.33e-06288224507666
Pubmed

Anti-oncogenic effects of tropomyosin: isoform specificity and importance of protein coding sequences.

TPM1 TPM2

6.33e-0628828760295
Pubmed

Several structural domains contribute to the regulation of N-type calcium channel inactivation by the beta 3 subunit.

CACNA1B CACNA2D1

6.33e-06288214602720
Pubmed

Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis.

TPM1 TPM2

6.33e-06288217416600
Pubmed

Renaturation of skeletal muscle tropomyosin: implications for in vivo assembly.

TPM1 TPM2

6.33e-0628823857586
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

6.33e-0628828898078
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

6.33e-06288214550562
Pubmed

Mutation update and genotype-phenotype correlations of novel and previously described mutations in TPM2 and TPM3 causing congenital myopathies.

TPM2 TPM3

6.33e-06288224692096
Pubmed

The molecular basis for tropomyosin isoform diversity.

TPM1 TPM3

6.33e-0628821796905
Pubmed

Elevated tropomyosin expression is associated with epithelial-mesenchymal transition of lens epithelial cells.

TPM1 TPM2

6.33e-06288223205574
Pubmed

Regulation of Actin Filament Length by Muscle Isoforms of Tropomyosin and Cofilin.

TPM1 TPM3

6.33e-06288232560136
Pubmed

Developmental analysis of tropomyosin gene expression in embryonic stem cells and mouse embryos.

TPM1 TPM2

6.33e-0628827684495
Pubmed

Munc18: a presynaptic transmitter release site N type (CaV2.2) calcium channel interacting protein.

CACNA1B STXBP1

6.33e-06288219170253
Pubmed

Specific features of neuronal size and shape are regulated by tropomyosin isoforms.

TPM1 TPM3

6.33e-06288215888546
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

6.33e-06288214985349
Pubmed

Novel mutations in TPM2 and PIEZO2 are responsible for distal arthrogryposis (DA) 2B and mild DA in two Chinese families.

TPM2 PIEZO2

6.33e-06288230285720
Pubmed

FGF2 antagonizes aberrant TGFβ regulation of tropomyosin: role for posterior capsule opacity.

TPM1 TPM2

6.33e-06288227976512
Pubmed

Human hTM alpha gene: expression in muscle and nonmuscle tissue.

TPM1 TPM3

6.33e-0628823336363
Pubmed

Divergent regulation of the sarcomere and the cytoskeleton.

TPM1 TPM3

6.33e-06288217951248
Pubmed

Tropomyosin in preimplantation mouse development: identification, expression, and organization during cell division and polarization.

TPM1 TPM3

6.33e-0628829473354
Pubmed

MusTRD can regulate postnatal fiber-specific expression.

TPM1 TPM2 TPM3

8.56e-061688316494860
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

TPM3 CEP170 LUC7L CACNA2D1 FLOT2 KRT78 PA2G4 ANXA6 ZNF638 EXOC3 NCL ASCC3

1.05e-051024881224711643
Pubmed

Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells.

TPM1 TPM2 TPM3 TPM4

1.10e-055488422266860
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TPM1 TPM3 CEP170 TPM4 MICAL1 CACNA2D1 FLOT2 KRT78 HNRNPCL1 STXBP1 NBEA NCL ATP2B3 HNRNPCL2

1.39e-051431881437142655
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

1.90e-05388218403125
Pubmed

Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta.

TPM1 TPM2

1.90e-05388215897890
Pubmed

Tropomyosin isoforms regulate cofilin 1 activity by modulating actin filament conformation.

TPM1 TPM3

1.90e-05388231996302
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

1.90e-05388218434746
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

1.90e-05388229730765
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

1.90e-0538829204703
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

1.90e-0538827876312
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

1.90e-05388221881589
Pubmed

Binding of pEL98 protein, an S100-related calcium-binding protein, to nonmuscle tropomyosin.

TPM2 TPM3

1.90e-0538828120097
Pubmed

Functional Assessment of Clubfoot Associated HOXA9, TPM1, and TPM2 Variants Suggests a Potential Gene Regulation Mechanism.

TPM1 TPM2

1.90e-05388227020427
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR2 RYR3

1.90e-05388212213830
Pubmed

PKA accelerates rate of force development in murine skinned myocardium expressing alpha- or beta-tropomyosin.

TPM1 TPM2

1.90e-05388211356630
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR2 RYR3

1.90e-0538829242641
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

1.90e-05388222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

1.90e-05388210788707
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

1.90e-05388215024040
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR2 RYR3

1.90e-05388225239916
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

1.90e-0538827621815
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR2 RYR3

1.90e-05388218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR2 RYR3

1.90e-05388211159936
Pubmed

Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.

CACNA1B CACNA2D1

1.90e-05388229208674
Pubmed

h2-Calponin is regulated by mechanical tension and modifies the function of actin cytoskeleton.

TPM3 TPM4

1.90e-05388216236705
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

1.90e-05388210473538
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR2 RYR3

1.90e-0538827959768
Pubmed

N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin.

TPM1 TPM3

1.90e-0538828886980
Pubmed

Targeted ablation of the murine alpha-tropomyosin gene.

TPM1 TPM2

1.90e-0538829400381
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR2 RYR3

1.90e-0538824600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR2 RYR3

1.90e-0538827635066
Pubmed

Functional proteomics mapping of a human signaling pathway.

TPM2 PPP1R8 ZBTB16 KMT2B L1TD1 ASCC3 NOMO3 RYR2 NOMO1

1.93e-0559188915231748
InteractionRYR2 interactions

TPM1 TPM2 TPM3 TPM4 NCL RYR2 RYR3

5.96e-0958887int:RYR2
InteractionPLCH2 interactions

TPM2 TPM3 TPM4 SSTR3

1.64e-0712884int:PLCH2
InteractionPIM3 interactions

TPM1 TPM2 TPM3 TPM4 HNRNPCL1 SFN

3.25e-0763886int:PIM3
InteractionZIC3 interactions

TPM1 TPM3 TPM4 FLOT2

4.00e-0625884int:ZIC3
InteractionPRKAG2 interactions

TPM1 TPM2 TPM3 TPM4 SSTR3

1.19e-0568885int:PRKAG2
InteractionDYRK3 interactions

TPM1 TPM2 TPM3 TPM4

3.68e-0543884int:DYRK3
InteractionRGS12 interactions

CACNA1B NBEA SSTR3 SFN

4.41e-0545884int:RGS12
InteractionTFPT interactions

TPM1 TPM2 TPM3 CEP170 ZNF638 ACTL6A

7.22e-05160886int:TFPT
InteractionNR3C1 interactions

FLOT2 ARRB1 ZBTB16 STXBP1 ANXA6 LMOD1 NBEA NCL UTY ATP2B3 NOMO3 HNRNPCL2 RYR2 SFN

7.88e-059748814int:NR3C1
InteractionSNAPIN interactions

TPM1 TPM2 TPM3 CEP170 TPM4 LAMA2

9.77e-05169886int:SNAPIN
InteractionSCN9A interactions

CACNA1B NCL SSTR3

1.01e-0421883int:SCN9A
InteractionACTN2 interactions

TPM1 TPM2 TPM3 TPM4 KCNA4 RYR2

1.04e-04171886int:ACTN2
InteractionMAST2 interactions

TPM1 TPM2 TPM3 SFN

1.20e-0458884int:MAST2
GeneFamilyTropomyosins

TPM1 TPM2 TPM3 TPM4

1.43e-104644777
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

3.69e-053642287
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

NASP ODAD4 IFIT2 UTY

7.35e-04115644769
GeneFamilyZinc fingers CXXC-type

KMT2B TET3

7.96e-0412642136
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEM POTEG

9.38e-0413642685
GeneFamilyDyneins, axonemal

DNAL4 DNAI2

1.62e-0317642536
GeneFamilyDNA helicases

NCL ASCC3

1.62e-03176421167
GeneFamilyWD repeat domain containing

CFAP251 DNAI2 WDR55 NBEA BRWD3

2.34e-03262645362
GeneFamilyCalcium voltage-gated channel subunits

CACNA1B CACNA2D1

3.80e-0326642253
GeneFamilyEF-hand domain containing

CACNA1B NKD1 RYR2 RYR3

7.55e-03219644863
CoexpressionLAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS

CACNA2D1 PIEZO2 ZBTB16 PTPRD LAMA2 NBEA ASCC3

2.28e-06177887M39245
CoexpressionAtlasBM Top 100 - saphenous vein

TPM1 TPM2 SHOX2 LMOD1 COL14A1

9.94e-0669885BM Top 100 - saphenous vein
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

TPM1 TPM2 TPM4 NKD1 SLC20A2 LMOD1 COL14A1 RYR2 RYR3

1.38e-1018888934e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 ZEB1 NKD1 LAMA2 LMOD1 RYR3

4.03e-09189888b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 ZEB1 NKD1 LAMA2 LMOD1 ADAMTS14

4.03e-09189888f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 ZEB1 NKD1 LMOD1 RCSD1 ADAMTS14 RYR3

4.03e-09189888da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 MASP1 NKD1 LAMA2 LMOD1 COL14A1 RYR2

4.20e-09190888562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 TPM4 PIEZO2 ZEB1 NKD1 LAMA2 LMOD1

4.20e-0919088870c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 MASP1 NKD1 LAMA2 LMOD1 COL14A1 RYR2

4.20e-09190888f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 ZEB1 NKD1 ANXA6 LMOD1 ADAMTS14

4.56e-091928887ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 PIEZO2 PTPRD ANXA6 LAMA2 COL14A1

5.36e-09196888dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 ZEB1 NKD1 ANXA6 LMOD1 RCSD1

5.81e-09198888637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 TPM4 TCEAL4 LAMA2 NASP LMOD1

6.28e-08177887b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

TPM1 TPM2 CACNA2D1 NKD1 LMOD1 COL14A1 RYR2

7.05e-08180887d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

TPM2 MASP1 NKD1 SHOX2 LMOD1 COL14A1 ADAMTS14

7.32e-0818188735c470988a93381eefa300831aabb813fa1b90bd
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 ZEB1 NKD1 LAMA2 LMOD1

7.89e-08183887e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

TPM1 TPM2 CACNA2D1 LAMA2 LMOD1 COL14A1 RYR2

9.15e-08187887464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPM1 CACNA2D1 MASP1 NKD1 LAMA2 LMOD1 RYR2

9.49e-08188887ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 ZEB1 NKD1 LMOD1 ADAMTS14

9.49e-081888873004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

TPM1 TPM2 TPM4 NKD1 LMOD1 COL14A1 RYR3

9.84e-081898876b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 TPM4 NKD1 LAMA2 LMOD1 RYR2

1.02e-071908872e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 TPM4 NKD1 LAMA2 LMOD1 RYR2

1.02e-071908870028f886c789ba238c031eae5d96acaed4af8c25
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPM2 TPM4 PIEZO2 ZEB1 NKD1 LAMA2 LMOD1

1.06e-07191887107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPM2 TPM4 PIEZO2 ZEB1 NKD1 LAMA2 LMOD1

1.06e-07191887bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPM1 CACNA2D1 PIEZO2 ZBTB16 NKD1 LAMA2 RYR2

1.18e-07194887e93de9428c986b8943fc169258847c650cfab0e5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA2D1 PIEZO2 ZBTB16 PTPRD NKD1 LAMA2 RYR2

1.18e-0719488735f132cc38ac133be01834ed0946188aa0757eb4
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 ZEB1 NKD1 ANXA6 LMOD1

1.22e-07195887dba2a87efd7e067c094c4b367feb4138cab62735
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 TPM2 TPM4 ZEB1 NKD1 ANXA6 LMOD1

1.22e-0719588726a3a5daf389606ef1ebb35533f12e60853b3a12
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPM2 ZBTB16 NKD1 LAMA2 LMOD1 COL14A1 RYR2

1.26e-071968871522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 PIEZO2 ZBTB16 NKD1 LAMA2 COL14A1 RYR2

1.26e-07196887bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPM2 ZBTB16 NKD1 LAMA2 LMOD1 COL14A1 RYR2

1.26e-071968871c8294014713684b50885e638668f2ce75f357f0
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 TPM2 TPM4 NKD1 LMOD1 COL14A1 RYR2

1.30e-07197887bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

TPM1 CACNA2D1 PIEZO2 PTPRD LAMA2 COL14A1 RYR2

1.30e-07197887f1c8936986123a3151140c374fcd62d6705c530b
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 MASP1 NKD1 ANXA6 LMOD1

1.35e-07198887c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 MASP1 NKD1 ANXA6 LMOD1

1.40e-07199887aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCellcellseq-Mesenchymal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TPM1 TPM2 NKD1 ANXA6 LAMA2 LMOD1 COL14A1

1.45e-07200887238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 TPM2 TPM4 NKD1 LMOD1 COL14A1 RYR2

1.45e-07200887a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 TPM2 TPM4 MASP1 NKD1 LMOD1 RYR2

1.45e-072008878158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 TPM2 TPM4 MASP1 NKD1 LMOD1 RYR2

1.45e-07200887600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TPM1 TPM2 SOX30 LMOD1 COL14A1 ADAMTS14

4.06e-071438869bfb3674c8f011b9cf928b522777b8d54478db8d
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

TPM1 TPM2 SLC20A2 LMOD1 RYR2 RYR3

6.03e-07153886ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

TPM1 TPM2 NKD1 LMOD1 CAMK1 RYR2

7.29e-071588868d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

TPM1 TPM2 LMOD1 COL14A1 RYR2 RYR3

8.13e-0716188664891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPM1 TPM2 CACNA2D1 NKD1 LMOD1 RYR2

9.39e-071658868a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 ZEB1 ZBTB16 NKD1 LAMA2 LMOD1

9.72e-0716688694636dbc039f794c735960c3425e00bdd5523602
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

TPM1 TPM2 CACNA2D1 LMOD1 COL14A1 RYR2

1.20e-06172886c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

TPM1 TPM2 LMOD1 COL14A1 RYR2 RYR3

1.24e-06173886a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TPM1 TPM2 CACNA2D1 LMOD1 COL14A1 RYR2

1.24e-06173886cb6389536195443633adb06e5f1b7483530773d1
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPM1 TPM2 CACNA2D1 NKD1 LMOD1 RYR2

1.24e-061738865416b092321c7d9b63f0418c60f2402a138355bf
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPM1 CACNA2D1 MASP1 NKD1 LMOD1 RYR2

1.61e-06181886451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

TPM1 TPM2 MASP1 NKD1 LMOD1 RYR2

1.61e-06181886f74941e49950027360d71ea3b205fc20c6929766
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TPM1 TPM2 ZEB1 NKD1 LAMA2 LMOD1

1.61e-06181886d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM4 NKD1 LAMA2 LMOD1 COL14A1

1.66e-0618288644764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM4 NKD1 LAMA2 LMOD1 COL14A1

1.66e-06182886d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

TPM1 TPM2 CACNA2D1 LAMA2 CHN2 RYR2

1.77e-06184886ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 MASP1 LAMA2 LMOD1 RYR2

1.88e-06186886888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 MASP1 ANXA6 LAMA2 LMOD1

1.94e-061878868ee3bf885897efd634c3a0567637142a9f55e693
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 ZEB1 NKD1 LMOD1 RYR3

2.00e-0618888674f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 TPM2 MASP1 NKD1 TCEAL4 LMOD1

2.00e-06188886879de94924de978478696fc7838e05a4d795b905
ToppCellfacs-BAT-Fat-3m|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPM4 ZBTB16 ANXA6 COL14A1 BIRC6 ANAPC5

2.07e-061898867ce71f9c81512ed38c804f025908746b4af3aab1
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA2D1 PIEZO2 PTPRD NKD1 LAMA2 COL14A1

2.07e-06189886203c80030df08ae112f9ae4043709f455d87ce89
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

MASP1 ZEB1 LAMA2 LMOD1 ADAMTS14 RYR2

2.07e-06189886d7ed96add29f219183c802895fbff519b627f635
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

TPM1 TPM2 CACNA2D1 PTPRD LAMA2 COL14A1

2.07e-061898860c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

TPM1 CACNA2D1 PIEZO2 NKD1 LAMA2 RYR2

2.13e-061908863a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 TPM2 TPM4 ANXA6 LMOD1 COL14A1

2.20e-0619188689d03c4133dda852a3713c0902a7d67941cf5b21
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

TPM1 TPM2 CACNA2D1 LMOD1 COL14A1 RYR2

2.20e-06191886fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TPM1 TPM2 ZEB1 LAMA2 LMOD1 ADAMTS14

2.26e-0619288667e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TPM1 PIEZO2 ZBTB16 NKD1 LAMA2 RYR2

2.26e-0619288699ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellE15.5-Mesenchymal-myocytic_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TPM1 TPM2 CACNA2D1 NKD1 ANXA6 LMOD1

2.33e-061938863316d6a39abb6a518d45b846254325fc7a8b2035
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 MASP1 ZBTB16 ANXA6 LMOD1

2.33e-0619388687ce81ff5b27d9c4300826d76ff5a62e9c408d5d
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM2 PIEZO2 TCEAL4 ANXA6 LAMA2 COL14A1

2.33e-061938865bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCellE15.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TPM1 TPM2 CACNA2D1 NKD1 ANXA6 LMOD1

2.33e-06193886e787e618f6e8a1e22be366ce606bf78831b60a90
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CACNA2D1 PIEZO2 PTPRD NKD1 LAMA2 RYR2

2.33e-06193886acad568621ed677031797b8c2e34dafea798d681
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TPM1 TPM2 ZEB1 LMOD1 ADAMTS14 RYR2

2.40e-061948862d66091097e106c7bee22e5281f50724700bdf8d
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 TPM2 ZEB1 NKD1 ANXA6 LMOD1

2.40e-0619488615060cc25baf49dd04d9c20499e28718610ef754
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 ZBTB16 NKD1 LMOD1 RYR2

2.40e-061948865c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 ZBTB16 NKD1 LMOD1 RYR2

2.40e-06194886ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 MASP1 ZEB1 NKD1 LMOD1

2.40e-0619488667f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell3'-Distal_airway-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 MASP1 ZBTB16 ANXA6 LMOD1

2.40e-06194886f5e3e675187afb6efa774f2a8d685efcf813de82
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 TPM2 TPM4 NKD1 ANXA6 LMOD1

2.48e-06195886bd7526dd80a60ff7bc866e4f5a0e8acdbc10d191
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 ZEB1 NKD1 LAMA2 LMOD1

2.48e-0619588649c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellE12.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TPM1 TPM2 TPM4 NKD1 ANXA6 LMOD1

2.48e-06195886bff7685784688425bebd78b0f284a6d4475a9415
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 TPM2 ZEB1 NKD1 LAMA2 LMOD1

2.48e-06195886dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellE12.5-Mesenchymal-myocytic_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TPM1 TPM2 TPM4 NKD1 ANXA6 LMOD1

2.48e-06195886aed243418cdb5df4563a7b935c1ecbd744590901
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 STXBP1 NBEA BOD1L1 ASCC3 UTY

2.48e-061958863e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPM2 CACNA2D1 ZBTB16 PTPRD LAMA2 ASCC3

2.48e-061958865c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

TPM2 PIEZO2 NKD1 LAMA2 LMOD1 RYR2

2.48e-06195886aa0add081881d349099d12efca5cdee098038d4e
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 NKD1 ANXA6 LMOD1 COL14A1

2.55e-06196886cda3681f032f740cb09c64c62b9153cb62dbb5d2
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

TPM1 TPM2 TPM4 ZEB1 NKD1 LMOD1

2.55e-0619688605530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 ZBTB16 ANXA6 LMOD1 COL14A1

2.55e-06196886f78951b460913866d092ba92af70ea76a2afa73e
ToppCellPND28-Mesenchymal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TPM1 TPM2 PTPRD LAMA2 LMOD1 COL14A1

2.55e-06196886119265efd2219f328d8152dbee52af8327aec89c
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 NKD1 ANXA6 LMOD1 COL14A1

2.55e-06196886b55aa507429ddce89ad4f42ab6daeca2f34fd676
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TPM2 PIEZO2 PTPRD SOX30 COL14A1 RYR2

2.55e-06196886614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 MASP1 NKD1 LMOD1 COL14A1

2.55e-061968868c25fa61c117a60ddd4cbd2f95ae5b66f986a1ec
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 ZBTB16 ANXA6 LMOD1 COL14A1

2.55e-0619688669ad90a429af4dad5a45556544224001ebcb1607
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 NKD1 ANXA6 LMOD1 COL14A1

2.55e-06196886208ddedd29e1b9ca89cbb9b527c2e193a44cada2
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 TPM2 ZBTB16 ANXA6 LMOD1 COL14A1

2.55e-061968864da96672a9c72268cfcc82d61eb3caae6e02d4c4
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 TPM2 TPM4 ANXA6 LMOD1 COL14A1

2.63e-06197886398a66c06df63567b176ab2cc85e27837e94d0d9
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TPM2 CACNA2D1 PIEZO2 PTPRD LAMA2 COL14A1

2.63e-0619788673a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellFibroblast|World / shred by cell class for bronchial biopsy

TPM1 TPM2 PIEZO2 ANXA6 LMOD1 COL14A1

2.63e-061978868bf9846228b6b6721b10375fe54a2fb389ff64a6
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 ZEB1 NKD1 LMOD1

2.63e-061978864797f414330316e2ac2cf7cd2570d991877d7a38
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TPM1 TPM2 TPM4 MASP1 ANXA6 LAMA2

2.63e-0619788644cd1ece3633a31e8c9b667cd3cbc2749c06f478
DrugCP-31

TPM1 TPM2 TPM3 TPM4 NCL

9.57e-119885CID000452624
Drugamphidinolide D

TPM1 TPM2 TPM3 TPM4

1.04e-095884CID006439238
Drugeudistomin M

TPM1 TPM2 TPM3 TPM4

1.04e-095884CID000145927
Drugdidansylcystine

TPM1 TPM2 TPM3 TPM4

3.11e-096884CID000167721
DrugTopanol Ca

TPM1 TPM2 TPM3 TPM4

7.23e-097884CID000092905
DrugTCNB

TPM1 TPM2 TPM3 TPM4 LAMA2 ACTL6A RYR2 RYR3

1.99e-08119888CID000008330
DrugNpCaM

TPM1 TPM2 TPM3 TPM4 ANXA6 ACTL6A

3.02e-0848886CID000122259
DrugIASL

TPM1 TPM2 TPM3 TPM4

4.30e-0810884CID002724305
DrugNSC3260

TPM1 TPM2 TPM3 TPM4 FLOT2 ACTL6A ATP2B3 RYR2 RYR3

6.57e-08195889CID000220461
DrugAC1NRD2N

TPM1 TPM2 TPM3 TPM4

1.01e-0712884CID005289322
DrugTMBr-3

TPM1 TPM2 TPM3 TPM4

1.45e-0713884CID000518955
DrugN,N'-p-phenylenedimaleimide

TPM1 TPM2 TPM3 TPM4 ACTL6A

1.96e-0734885CID000076765
DrugAC1MP21W

TPM1 TPM2 TPM3 TPM4

2.02e-0714884CID003378340
Druggoniodomin A

TPM1 TPM2 TPM3 TPM4

2.02e-0714884CID006440832
DrugAC1NSKFN

TPM1 TPM2 TPM3 TPM4 ACTL6A

2.64e-0736885CID005311324
DrugK-Cl

TPM1 TPM2 TPM3 TPM4 CACNA1B CACNA2D1 ZEB1 LDHAL6A NCL ACTL6A ATP2B3 RYR2 RYR3

2.69e-075678813CID000004873
Drugconen

TPM1 TPM2 TPM3 TPM4

2.75e-0715884CID000093117
DrugA-G-T-C

TPM1 TPM2 TPM3 TPM4

2.75e-0715884CID003037868
DrugAC1Q5G4B

TPM1 TPM2 TPM3 TPM4 BIRC6

3.49e-0738885CID000207983
DrugDABMI

TPM1 TPM2 TPM3 TPM4

4.77e-0717884CID000137371
Drugethylene glycol tetraacetic acid

TPM1 TPM2 TPM3 TPM4 CACNA2D1

7.41e-0744885CID000006207
Drugbenzophenone-4-iodoacetamide

TPM1 TPM2 TPM3 TPM4

7.72e-0719884CID000131289
Drugchloro-m-cresol

CACNA2D1 RYR2 RYR3

1.11e-066883CID000012008
Drug7-azatryptophan

TPM1 TPM2 TPM3 TPM4

1.74e-0623884CID005354789
Drugdansylaziridine

TPM1 TPM2 TPM3 TPM4

1.74e-0623884CID000104008
DrugAzumoleno

CACNA2D1 RYR2 RYR3

1.93e-067883CID000056259
DrugNSC 32050

TPM1 TPM2 TPM3 TPM4

4.60e-0629884CID000022780
Drug5-IAF

TPM1 TPM2 TPM3 TPM4 ACTL6A

5.71e-0666885CID000123822
Druggallopamil

CACNA1B CACNA2D1 BIRC6 RYR2 RYR3

6.15e-0667885CID000001234
DrugNSC7524

CACNA1B CACNA2D1 LDHAL6A ANXA6 CAMK1 RYR2 RYR3

6.84e-06182887CID000005657
DrugAC1MNW2N

TPM1 TPM2 TPM3 TPM4 ACTL6A

7.64e-0670885CID003359490
DrugCNS 1145

CACNA1B CACNA2D1 RYR2 RYR3

7.82e-0633884CID000190902
DrugIHC-64

CACNA1B CACNA2D1 RYR2 RYR3

7.82e-0633884CID000162753
Drugfluo-3

CACNA2D1 PTPRD ABCB5 ATP2B3 RYR2 RYR3

7.92e-06122886CID000104978
DrugDichloro-phen

TPM1 TPM2 TPM3 TPM4

8.84e-0634884CID000003037
Drugdihydropyridine

CACNA1B CACNA2D1 ABCB5 COL14A1 ATP2B3 RYR2 RYR3

1.00e-05193887CID000104822
Druguranyl acetate

TPM1 TPM2 TPM3 TPM4

1.12e-0536884CID000010915
Drugnisoldipine

CACNA1B CACNA2D1 LDHAL6A RYR2 RYR3

1.30e-0578885CID000004499
DrugXeC compound

CACNA1B CACNA2D1 ATP2B3 RYR2 RYR3

1.87e-0584885CID000005701
Drugnimodipine

CACNA1B CACNA2D1 ABCB5 ATP2B3 RYR2 RYR3

2.12e-05145886CID000004497
Drug3-(2-carboxyindol-3-yl)propionic acid

TPM1 TPM2 TPM3 TPM4

2.29e-0543884CID000169313
Drugsilaned

TPM1 TPM2 TPM3 TPM4

2.29e-0543884CID006335299
Drugfluorescein isothiocyanate

TPM1 TPM2 TPM3 TPM4 ACTL6A ATP2B3

2.29e-05147886CID000018730
DrugFPL 64176

CACNA2D1 RYR2 RYR3

2.45e-0515883CID000003423
DrugBay K 8644

CACNA1B CACNA2D1 KCNA4 ATP2B3 RYR2 RYR3

2.57e-05150886CID000002303
Drugbenzophenone-4-maleimide

TPM1 TPM2 TPM3 TPM4

2.75e-0545884CID000146390
DrugAC1L9NBR

TPM1 TPM2 TPM3 TPM4 ABCB5

2.90e-0592885CID000449625
Drugnor-BNI

TPM3 CEP170 CACNA1B LMOD1

3.00e-0546884CID000004533
Drugnifedipine

CACNA1B CACNA2D1 LDHAL6A ABCB5 COL14A1 BIRC6 ATP2B3 RYR2 RYR3

3.26e-05415889CID000004485
Drugpemoline

TPM1 TPM2 TPM3 TPM4

3.27e-0547884CID000004723
Drug3-(1H-pyrrole-2-carboxylate

CACNA1B CACNA2D1 ANXA6 CAMK1 ATP2B3 RYR2 RYR3

3.37e-05233887CID000005114
Drugmanidipine

CACNA1B CACNA2D1 ACTL6A RYR2 RYR3

3.39e-0595885CID000004008
Drugisotetrandrine

CACNA1B CACNA2D1 ABCB5 RYR2 RYR3

3.75e-0597885CID000005422
DrugG 2 (antioxidant)

TPM1 TPM2 TPM3 TPM4

3.87e-0549884CID000202003
Drug2-hydroxycarbazole

RYR2 RYR3

4.42e-053882CID000093551
Drugcis-diammineplatinum(II

RYR2 RYR3

4.42e-053882CID000159790
Drug2-hydroxyheptanoic acid

RYR2 RYR3

4.42e-053882CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR2 RYR3

4.42e-053882CID005748312
Drug8N3-cADPR

RYR2 RYR3

4.42e-053882CID000127713
Drugaminodantrolene

RYR2 RYR3

4.42e-053882CID009570289
Drugloperamide

CACNA1B CACNA2D1 ABCB5 RYR2 RYR3

5.48e-05105885CID000003954
Drugdansyl chloride

TPM1 TPM2 TPM3 TPM4 CAMK1

6.27e-05108885CID000011801
DrugCinildipine

CACNA1B CACNA2D1 RYR2 RYR3

6.56e-0556884CID000002752
Drugacrylodan

TPM1 TPM2 TPM3 TPM4

6.56e-0556884CID000104901
DrugAC1NSKPI

TPM1 ABCB5 ANXA6 ATP2B3

7.04e-0557884CID005311482
Drugindo-1/AM

CACNA2D1 RYR2 RYR3

7.06e-0521883CID000123918
Drugthulium

TPM1 TPM2 TPM3 TPM4 ABCB5

7.14e-05111885CID000023961
Drugpurealin

TPM1 TPM2 TPM3 TPM4

7.54e-0558884CID006419303
Drugetorphine

CACNA1B CACNA2D1 ARRB1 SSTR3

8.06e-0559884CID000026721
Drugnilvadipine

CACNA1B CACNA2D1 RYR2 RYR3

8.61e-0560884CID000004494
DrugAC 110

CACNA1B CACNA2D1

8.82e-054882CID000022860
DrugPCB74

RYR2 RYR3

8.82e-054882CID000036218
Drug148504-47-6

RYR2 RYR3

8.82e-054882CID006444275
DrugAHC-52

CACNA2D1 ABCB5

8.82e-054882CID000164115
DrugSC 38249

RYR2 RYR3

8.82e-054882CID000134834
Drugteludipine

CACNA2D1 ABCB5

8.82e-054882CID006436165
DrugGabapentin

CACNA1B CACNA2D1

8.82e-054882DB00996
DrugAC1L1U7A

RYR2 RYR3

8.82e-054882CID000035682
DrugIAA-94

CACNA1B CACNA2D1 RYR2 RYR3

9.19e-0561884CID000003667
DrugNSC759576

CACNA1B CACNA2D1 ABCB5 BIRC6 RYR2 RYR3

9.87e-05191886CID000003075
Druglercanidipine

CACNA1B CACNA2D1 RYR2 RYR3

1.04e-0463884CID000065866
DrugEthambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A

TPM1 ARRB1 SHOX2 LMOD1 COL14A1 CAMK1

1.17e-041978864120_UP
DrugVigabatrin [60643-86-9]; Up 200; 31uM; PC3; HT_HG-U133A

TPM1 TPM2 CACNA2D1 DNAL4 KMT2B UTY

1.17e-041978866314_UP
DrugMyosmine [532-12-7]; Up 200; 27.4uM; PC3; HT_HG-U133A

TPM3 CACNA2D1 L1TD1 SHOX2 LMOD1 UTY

1.20e-041988864293_UP
DrugQuinic acid [86-68-0]; Down 200; 19.6uM; MCF7; HT_HG-U133A

MICAL1 NEK1 ZEB1 SLC20A2 COL14A1 RYR2

1.20e-041988863540_DN
DrugAC1L1I3V

CACNA2D1 BIRC6 RYR2

1.21e-0425883CID000004411
Drugbepridil

CACNA1B CACNA2D1 BIRC6 RYR2 RYR3

1.30e-04126885CID000002351
DrugS 8510

CACNA1B CACNA2D1

1.47e-045882CID005488383
DrugSdz 280 446

CACNA2D1 ABCB5

1.47e-045882CID000164287
DrugSDB-ethylenediamine

CACNA2D1 ABCB5

1.47e-045882CID006438957
DrugAC1L2AC7

CACNA1B CACNA2D1 RYR2 RYR3

1.49e-0469884CID000068733
Drugeniluracil

CACNA1B CACNA2D1 SSTR3

1.53e-0427883CID000043157
Drugpyrene

TPM1 TPM2 TPM3 TPM4 ACTL6A

1.56e-04131885CID000031423
DrugAC1L1D8L

STK10 ZBTB16 RYR2 RYR3

1.66e-0471884CID000002241
Drugflecainide

CACNA2D1 KCNA4 RYR2 RYR3

1.66e-0471884CID000003355
Drugazidopine

TPM3 CACNA2D1 ABCB5

1.70e-0428883CID000656406
DrugCAS 298-57-7

CACNA1B CACNA2D1 RYR2 RYR3

1.85e-0473884CID000002761
Druglanthanum

CACNA1B CACNA2D1 ATP2B3 RYR2 RYR3

1.86e-04136885CID000023926
DrugAC1NRBPQ

TPM1 TPM2 TPM3 TPM4 ACTL6A

1.92e-04137885CID005288569
DrugAC1L1B35

TPM1 TPM2 TPM3 TPM4

1.95e-0474884CID000001263
Diseasealcohol use disorder (implicated_via_orthology)

RHBDL2 STXBP1 ACTL6A UTY RYR2 RYR3

2.04e-05195846DOID:1574 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

2.40e-053842DOID:3529 (implicated_via_orthology)
DiseaseCap Myopathy

TPM2 TPM3

2.40e-053842C3710589
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

2.40e-053842DOID:8545 (implicated_via_orthology)
DiseaseInflammatory Myofibroblastic Tumor

TPM3 TPM4

1.19e-046842C0334121
DiseaseARTHROGRYPOSIS, DISTAL, TYPE 2B

TPM2 PIEZO2

1.19e-046842C1834523
DiseaseCongenital myopathy with fiber type disproportion

TPM2 TPM3

1.19e-046842cv:C0546264
DiseaseNemaline Myopathy, Childhood Onset

TPM2 TPM3

1.67e-047842C0546125
DiseaseMyopathies, Nemaline

TPM2 TPM3

2.22e-048842C0206157
DiseaseNemaline myopathy

TPM2 TPM3

2.22e-048842cv:C0206157
DiseaseDistal arthrogryposis

TPM2 PIEZO2

2.85e-049842cv:C0265213
DiseaseIntellectual Disability

CACNA1B ZBTB40 NBEA ACTL6A ASCC3 TET3 BRWD3

2.90e-04447847C3714756
DiseaseMacrocephaly

TET3 BRWD3

4.33e-0411842C0221355
DiseaseCongenital myopathy (disorder)

TPM2 TPM3

5.19e-0412842C0270960
DiseaseGlobal developmental delay

CACNA1B NBEA ACTL6A TET3

5.76e-04133844C0557874
DiseaseAutosomal Dominant Myotubular Myopathy

TPM2 TPM3

6.12e-0413842C3661489
DiseaseCentronuclear myopathy

TPM2 TPM3

6.12e-0413842C0175709
Diseasesalicylurate measurement

ZNF638 RYR2

6.12e-0413842EFO_0010532
DiseaseX-linked centronuclear myopathy

TPM2 TPM3

6.12e-0413842C0410203
DiseaseCongenital Structural Myopathy

TPM2 TPM3

6.12e-0413842C0752282
DiseaseMyopathy, Centronuclear, 1

TPM2 TPM3

6.12e-0413842C4551952
DiseaseMyopathy, Centronuclear, Autosomal Dominant

TPM2 TPM3

7.13e-0414842C1834558
DiseaseTubular Aggregate Myopathy

TPM2 TPM3

7.13e-0414842C0410207
Diseaseunipolar depression, mood disorder, response to antidepressant

SLC4A8 PTPRD

7.13e-0414842EFO_0003761, EFO_0004247, GO_0036276
DiseaseAutosomal Recessive Centronuclear Myopathy

TPM2 TPM3

8.21e-0415842C3645536
Diseaseerythritol measurement

CACNA2D1 NASP

1.06e-0317842EFO_0021171
DiseaseCongenital Fiber Type Disproportion

TPM2 TPM3

1.19e-0318842C0546264
Diseaseintellectual disability (implicated_via_orthology)

NDST2 BOD1L1 SFN

1.30e-0375843DOID:1059 (implicated_via_orthology)
DiseaseEsophageal Neoplasms

TPM1 TPM4 SFN

1.45e-0378843C0014859
DiseaseMalignant neoplasm of esophagus

TPM1 TPM4 SFN

1.45e-0378843C0546837
Diseaseexercise test

PTPRD RYR2

1.47e-0320842EFO_0004328
DiseaseLiver Cirrhosis, Experimental

TPM1 TPM3 TPM4 STK10 PTPRD NBEA RCSD1 RDH13

1.63e-03774848C0023893
DiseaseAutism Spectrum Disorders

NEMF TET3 RYR2

1.86e-0385843C1510586
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

ZBTB16 CHFR LAMA2 NBEA ASCC3 BIRC6 TET3 RYR2

2.02e-03801848EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseSquamous cell carcinoma of esophagus

TPM1 TPM2 SFN

2.55e-0395843C0279626
Diseaseazoospermia (implicated_via_orthology)

PTPRD NDST2

2.68e-0327842DOID:14227 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
SEEVEARKMIDKVFG

CEP170

511

Q5SW79
EMVSEDEDGKLGFKV

BIRC6

4541

Q9NR09
MKGAVEKGEELSCEE

SFN

26

P31947
RMTDDIDKISDGIGD

ABCB5

166

Q2M3G0
KIGEAEAAVIEAMGK

FLOT2

321

Q14254
ERDDGSTLMEIDGDK

ACTL6A

46

O96019
EEKPAGEEAEMEKAT

RCSD1

301

Q6JBY9
GEEAEMEKATEVKGE

RCSD1

306

Q6JBY9
EDENMGGEDKEKKET

BRWD3

1581

Q6RI45
EMRLKEKGKAEGRDE

DNAI2

516

Q9GZS0
EGKKEVEADDVMRSG

CACNA1B

1106

Q00975
LKGMKDDKEEEEDGT

ARRB1

396

P49407
SAEGGEMEEREKKKA

ATP2B3

336

Q16720
DKEVGSMKADDKCGV

ADAMTS14

691

Q8WXS8
KAMEGAGTDEKALIE

ANXA6

446

P08133
EGEEEGKEDKKIVME

CFAP251

61

Q8TBY9
GLGSGDEKKMERVSE

NKD1

96

Q969G9
REKNGNEEGEERMTK

NOMO3

721

P69849
DEGERKMEKEELDVS

ANAPC5

181

Q9UJX4
RAFEDEKKARMGVVE

PA2G4

281

Q9UQ80
KDETHVKMESEGGAE

HNRNPCL1

231

O60812
REKNGNEEGEERMTK

NOMO2

721

Q5JPE7
GKMASRRSEEKEAGE

LUC7L

356

Q9NQ29
KDETHVKMESEGGAE

HNRNPCL2

231

B2RXH8
GQEGSEEADMRRKKI

NEK1

591

Q96PY6
EVRKDQDSVGEMKDE

NEMF

756

O60524
MAEEKGGKQVLEESA

CFAP58

1

Q5T655
MGETEGKKDEADYKR

DNAL4

1

O96015
RAGGNTDMKKEDEKV

LMOD1

241

P29536
GSKERMCGEELEDTK

FAM169B

151

Q8N8A8
REKNGNEEGEERMTK

NOMO1

721

Q15155
DVDGVFLSKMELEGK

KRT78

221

Q8N1N4
AEDAGGKKLRLEMEA

MICAL1

651

Q8TDZ2
KLFGESRGENEEMEK

LAMA2

1756

P24043
KEGEEKEERAVAEEM

KMT2B

376

Q9UMN6
GKTREGAEDKMTSGD

BPNT2

96

Q9NX62
DKEQDSEMEKGGRED

NASP

171

P49321
AKEAMEDGEIDGNKV

NCL

626

P19338
DMEKCEAAAKDIRGE

RDH13

71

Q8NBN7
IAKEALEGKEGSMEN

CAMK1

51

Q14012
TREAIGHMKEGEEEK

PUS10

396

Q3MIT2
ERAGTVMEEKDGSGI

BOD1L1

2241

Q8NFC6
IEDVKMAFDRDGEKA

CHN2

321

P52757
EDVRAAAGKPDKMEE

CHFR

286

Q96EP1
KVEIRNKMIDGESGE

CACNA2D1

571

P54289
EGLAGDEKEMKIGET

COL14A1

481

Q05707
TRDMICAGEKEGGKD

MASP1

626

P48740
KMREEGEEEGEGEKL

IFIT2

221

P09913
EERKEGAEKMVREAE

EXOC3

621

O60645
AEAEIEAEEGGVEMK

SLC20A2

441

Q08357
EKLDVGVRKEVDGMG

RYR2

336

Q92736
DGKMVEEVDGRATQK

PTPRD

1056

P23468
GDEAKKMAEGKASRE

UTY

16

O14607
AVKGDEKMGGEDDEL

PPP1R8

136

Q12972
EEEKMREDGGGKDRA

RHBDL2

26

Q9NX52
EDGEESREGGKGKEM

SSTR3

356

P32745
EIGETKKTGNEMEKE

ODAD4

656

Q96NG3
TTGAKGGMEIREIED

NBEA

991

Q8NFP9
KDRKEDAKGMEDEGQ

SHOX2

121

O60902
EEEAEKMLEIGGDKF

SLC4A8

1026

Q2Y0W8
DLAMGTDAEGEKIKD

STXBP1

371

P61764
DEKGKLEAEEVMRDS

SOX30

181

O94993
EKKAGEDLEVSEGLM

ASCC3

351

Q8N3C0
KGMEGSEIVEEDVNK

CLUAP1

111

Q96AJ1
AKEGKSEREGESEME

TCEAL4

71

Q96EI5
TMADGGAEEEEDRKA

ZBTB16

136

Q05516
EKAADESERGMKVIE

TPM4

81

P67936
MKAERGVEAAEEKFE

TIGD1

116

Q96MW7
AEGKVESEKADMEDG

RYR3

4336

Q15413
KAEVMEEIEDGRDEG

STK10

311

O94804
DGVEGELEESTKLKM

PIEZO2

186

Q9H5I5
AMDTGTKEAGKDGRE

TLL2

111

Q9Y6L7
AAVEKEGEAGAAMEE

TSPYL4

161

Q9UJ04
EGEAGAAMEEKKVVQ

TSPYL4

166

Q9UJ04
DIDDIFVGKEGTRMK

NDST2

316

P52849
FVGKEGTRMKVADVE

NDST2

321

P52849
LEGKIKSVVMEGGEE

TET3

286

O43151
ENEGEEAKTEGLMKD

ZEB1

1081

P37275
AEKAADESERGMKVI

TPM1

116

P09493
GLREEGEDSMAQEEK

WDR55

361

Q9H6Y2
AEKAADESERGMKVI

TPM2

116

P07951
DKIGMEVKVDSDAGI

TSBP1

286

Q5SRN2
EINKGGDRKVEEEMK

POTEG

406

Q6S5H5
EINKGGDRKVEEEMK

POTEM

406

A6NI47
EAEKAADESERGMKV

TPM3

116

P06753
IGTEKAEKNEGRMDA

ZNF638

1326

Q14966
GEREVMEKLVKRDSG

ZBTB40

496

Q9NUA8
AMGQEKDGEERDSKE

ZNF541

931

Q9H0D2
GDKSEYLEMEEGVKE

KCNA4

606

P22459
GGQEMMEVVKRDDET

LDAH

241

Q9H6V9
VDVDEGKLKGETMDL

LDHAL6A

51

Q6ZMR3
KDGEDEFVKEMREER

L1TD1

201

Q5T7N2