Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	non-motile cilium membrane	CNGB1 CNGA4	8.81e-05	3	114	2	GO:0098804
GeneOntologyCellularComponent	histone deacetylase complex	HDAC7 NCOR1 NCOR2 RCOR1 CHD5	1.02e-04	85	114	5	GO:0000118
GeneOntologyCellularComponent	cochlear hair cell ribbon synapse	CACNA1D OTOF	4.36e-04	6	114	2	GO:0098683
GeneOntologyCellularComponent	intracellular cyclic nucleotide activated cation channel complex	CNGB1 CNGA4	6.08e-04	7	114	2	GO:0017071
GeneOntologyCellularComponent	nuclear matrix	STAG1 SPTBN4 NCOR2 PBRM1 PSPC1	1.03e-03	140	114	5	GO:0016363
GeneOntologyCellularComponent	axon hillock	SPTBN4 TPX2	1.04e-03	9	114	2	GO:0043203
GeneOntologyCellularComponent	spectrin	SPTAN1 SPTBN4	1.04e-03	9	114	2	GO:0008091
GeneOntologyCellularComponent	chromatin	STAG1 CALCOCO1 KLF15 FOXN3 CREBZF NCOR1 NCOR2 PBRM1 SF3B3 ZBED4 FERD3L NFIL3 CHD5 SHPRH ZFHX2 KDM4A VSX2 SLX4	1.07e-03	1480	114	18	GO:0000785
Domain	MYB_LIKE	BDP1 NCOR1 NCOR2 RCOR1 CDC5L	2.91e-06	38	111	5	PS50090
Domain	SANT	BDP1 NCOR1 NCOR2 RCOR1 CDC5L	1.16e-05	50	111	5	SM00717
Domain	SANT/Myb	BDP1 NCOR1 NCOR2 RCOR1 CDC5L	1.41e-05	52	111	5	IPR001005
Domain	N-CoR_GPS2_interact	NCOR1 NCOR2	3.50e-05	2	111	2	IPR031557
Domain	GPS2_interact	NCOR1 NCOR2	3.50e-05	2	111	2	PF15784
Domain	DH_1	MCF2L2 PLEKHG2 ARHGEF10 FGD1 AKAP13	3.62e-05	63	111	5	PS00741
Domain	RhoGEF	MCF2L2 PLEKHG2 ARHGEF10 FGD1 AKAP13	5.24e-05	68	111	5	SM00325
Domain	Myb_DNA-binding	NCOR1 NCOR2 RCOR1 CDC5L	5.37e-05	35	111	4	PF00249
Domain	RhoGEF	MCF2L2 PLEKHG2 ARHGEF10 FGD1 AKAP13	6.03e-05	70	111	5	PF00621
Domain	DH_2	MCF2L2 PLEKHG2 ARHGEF10 FGD1 AKAP13	6.03e-05	70	111	5	PS50010
Domain	DH-domain	MCF2L2 PLEKHG2 ARHGEF10 FGD1 AKAP13	6.45e-05	71	111	5	IPR000219
Domain	-	MCF2L2 PLEKHG2 ARHGEF10 FGD1 AKAP13	6.45e-05	71	111	5	1.20.900.10
Domain	CAC1F_C	CACNA1C CACNA1D	1.05e-04	3	111	2	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1D	1.05e-04	3	111	2	PF16885
Domain	VDCC_L_a1su	CACNA1C CACNA1D	2.08e-04	4	111	2	IPR005446
Domain	SANT_dom	NCOR1 NCOR2 RCOR1	4.81e-04	26	111	3	IPR017884
Domain	SANT	NCOR1 NCOR2 RCOR1	6.01e-04	28	111	3	PS51293
Domain	VDCC_a1su_IQ	CACNA1C CACNA1D	7.21e-04	7	111	2	IPR014873
Domain	GPHH	CACNA1C CACNA1D	7.21e-04	7	111	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1D	7.21e-04	7	111	2	IPR031649
Domain	Ca_chan_IQ	CACNA1C CACNA1D	7.21e-04	7	111	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1D	7.21e-04	7	111	2	PF08763
Domain	Spectrin/alpha-actinin	SPTAN1 MCF2L2 SPTBN4	8.94e-04	32	111	3	IPR018159
Domain	SPEC	SPTAN1 MCF2L2 SPTBN4	8.94e-04	32	111	3	SM00150
Domain	PH_dom-like	MYO7A MYO7B MCF2L2 PLEKHG2 WDFY4 SPTBN4 ARHGEF10 FGD1 AKAP13	9.98e-04	426	111	9	IPR011993
Domain	Cl-channel_core	CLCN5 CLCN7	1.23e-03	9	111	2	IPR014743
Domain	-	CLCN5 CLCN7	1.23e-03	9	111	2	1.10.3080.10
Domain	MYTH4	MYO7A MYO7B	1.23e-03	9	111	2	PS51016
Domain	MyTH4_dom	MYO7A MYO7B	1.23e-03	9	111	2	IPR000857
Domain	Voltage_CLC	CLCN5 CLCN7	1.23e-03	9	111	2	PF00654
Domain	Cl-channel_volt-gated	CLCN5 CLCN7	1.23e-03	9	111	2	IPR001807
Domain	MyTH4	MYO7A MYO7B	1.23e-03	9	111	2	PF00784
Domain	MyTH4	MYO7A MYO7B	1.23e-03	9	111	2	SM00139
Domain	VDCCAlpha1	CACNA1C CACNA1D	1.53e-03	10	111	2	IPR002077
Domain	Znf_FYVE_PHD	RBSN CHD5 SHPRH FGD1 KDM4A	1.85e-03	147	111	5	IPR011011
Domain	WD40_repeat_dom	LRRK2 WDR55 WDFY4 FBXW8 SF3B3 ARHGEF10 HERC1	1.99e-03	297	111	7	IPR017986
Domain	Homeodomain-like	BDP1 NCOR1 NCOR2 RCOR1 ZFHX2 CDC5L VSX2	3.69e-03	332	111	7	IPR009057
Domain	WD40/YVTN_repeat-like_dom	LRRK2 WDR55 WDFY4 FBXW8 SF3B3 ARHGEF10 HERC1	3.88e-03	335	111	7	IPR015943
Domain	CBS	CLCN5 CLCN7	3.98e-03	16	111	2	SM00116
Domain	cNMP-bd_CS	CNGB1 CNGA4	3.98e-03	16	111	2	IPR018488
Domain	Ion_trans_dom	CACNA1C CACNA1D CNGB1 CNGA4	4.78e-03	114	111	4	IPR005821
Domain	Ion_trans	CACNA1C CACNA1D CNGB1 CNGA4	4.78e-03	114	111	4	PF00520
Domain	-	RBBP6 RBSN RNF123 CHD5 SHPRH FGD1 KDM4A SYVN1	5.36e-03	449	111	8	3.30.40.10
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	HDAC7 NCOR1 NCOR2 NOTCH3	2.05e-05	28	83	4	M6177
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	MYO7B PBRM1 SF3B3 OTOF TPX2 GIGYF2 PPIP5K1 CDC5L HERC1 HSP90AB1	7.46e-09	234	117	10	36243803
Pubmed	Defining the membrane proteome of NK cells.	FKBP15 MFSD6 NCAPH2 NCOR1 NCOR2 CLCN5 CLCN7 MAP4K1 CHD5 HPS6 GIGYF2 AKAP13 EIF3A GNAS CDC5L SYVN1 BAG6 PIGO HSP90AB1	1.32e-08	1168	117	19	19946888
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SZT2 MYO7A PUF60 HECTD4 EXTL3 STK32C HDAC7 NCOR1 NCOR2 ZBED4 CLCN7 SUGP2 CHD5 HPS6 TMEM132A AKAP13 HERC1 SYVN1	3.25e-08	1105	117	18	35748872
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	NES PUF60 NCBP3 FBXW8 PBRM1 SF3B3 SUGP2 CIZ1 TJP2 GIGYF2 UTP20 EIF3A GNAS CDC5L PSPC1 BAG6 HSP90AB1	6.22e-08	1024	117	17	24711643
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	STAG1 L3MBTL2 CALCOCO1 STRIP1 TASOR2 PPP1R7 RCOR1 PBRM1 SF3B3 TSR1 TPX2 CCSER2 CIZ1 EIF3A GNAS CDC5L PDCD10 SLX4	6.32e-08	1155	117	18	20360068
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	BDP1 CACNA1C HGH1 MYO7A CT47A1 NCBP3 SHPRH TJP2 GIGYF2 KDM4A HERC1 BAG6	1.25e-07	497	117	12	36774506
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RBBP6 PUF60 ZFC3H1 NCOR1 PBRM1 SF3B3 SUGP2 TSR1 TPX2 TJP2 GIGYF2 UTP20 EIF3A CDC5L PSPC1	1.75e-07	847	117	15	35850772
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	STAG1 L3MBTL2 PUF60 WDR55 FOXN3 P3H4 NCOR1 NCOR2 FBXW8 SUGP2 NFIL3 TPX2 UTP20 NOTCH3 HSP90AB1	2.03e-07	857	117	15	25609649
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	PUF60 HDAC7 SF3B3 PI4KB SHPRH TJP2 AKAP13 CDC5L HSP90AB1	2.21e-07	255	117	9	15324660
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PCNP FKBP15 RBBP6 PUF60 WDR55 NCOR1 NCOR2 RCOR1 PBRM1 SF3B3 SUGP2 TSR1 TPX2 EIF3A CDC5L PSPC1	3.11e-07	1014	117	16	32416067
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBBP6 SPTAN1 HDAC7 STRIP1 NCOR1 NCOR2 SUGP2 MAP4K1 TPX2 TJP2 GIGYF2 UTP20 BAG6 HSP90AB1	3.61e-07	774	117	14	15302935
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	PUF60 TASOR2 PBRM1 SF3B3 SUGP2 TSR1 CHD5 EIF3A PSPC1	3.68e-07	271	117	9	32433965
Pubmed	Combinatorial roles of the nuclear receptor corepressor in transcription and development.	NES NCOR1 NCOR2	3.69e-07	5	117	3	11030619
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	RBBP6 SPTAN1 NCBP3 SF3B3 SUGP2 TJP2 GIGYF2 EIF3A HSP90AB1	4.03e-07	274	117	9	34244482
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	CACNA1C PUF60 CALCOCO1 STK32C TASOR2 SPTBN4 PI4KB EIF3A PSPC1 CCDC136 NOTCH3 HSP90AB1	4.47e-07	560	117	12	21653829
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBBP6 PUF60 TASOR2 NCBP3 NCOR1 NCOR2 SF3B3 SUGP2 TPX2 CIZ1 GIGYF2 CDC5L PSPC1 SLX4 HSP90AB1	7.85e-07	954	117	15	36373674
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	PUF60 NCOR1 NCOR2 PBRM1 SF3B3 SUGP2 CDC5L PSPC1	8.52e-07	220	117	8	35785414
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	FKBP15 NES SPTAN1 CALCOCO1 HECTD4 STRIP1 SPTBN4 PPP1R7 NCOR1 NCOR2 RCOR1 PBRM1 GIGYF2 CDC5L HSP90AB1	8.82e-07	963	117	15	28671696
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	CACNA1C TSNAXIP1 RILPL2 STAG1 L3MBTL2 PBRM1 TSR1 GIGYF2 KDM4A	9.31e-07	303	117	9	25056061
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NES SPTAN1 PLEKHG2 STK32C HDAC7 RBSN ARHGEF10 MAP4K1 PI4KB CCSER2 TJP2 GIGYF2 AKAP13 GNAS	1.27e-06	861	117	14	36931259
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PUF60 IRGQ HDAC7 STRIP1 PPP1R7 RNF123 SF3B3 TSR1 PI4KB TJP2 AKAP13 EIF3A GNAS CDC5L HERC1 PDCD10 BAG6	1.45e-06	1284	117	17	17353931
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	PCNP RBBP6 PUF60 SPTAN1 NCOR1 SUGP2 TPX2 CIZ1 TJP2 GIGYF2 CDC5L	2.64e-06	549	117	11	38280479
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	PCNP L3MBTL2 SPTAN1 TASOR2 SF3B3 CIZ1 GIGYF2 EIF3A CDC5L PSPC1 HSP90AB1	2.73e-06	551	117	11	34728620
Pubmed	Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.	HDAC7 NCOR1 NCOR2	3.07e-06	9	117	3	11466315
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RBBP6 PUF60 SPTAN1 ZFC3H1 TASOR2 SF3B3 TSR1 CHD5 TPX2 TJP2 UTP20 EIF3A GNAS CDC5L PSPC1 HSP90AB1	5.03e-06	1257	117	16	36526897
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	STAG1 SPTAN1 MCF2L2 HECTD4 NCAPH2 EXTL3 ZFC3H1 CREBZF SPTBN4 RNF123 OTOF ARHGEF10 KDM4A SLX4 MRFAP1L1 HSP90AB1	6.63e-06	1285	117	16	35914814
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RBBP6 STRIP1 NCOR1 RBSN PBRM1 TPX2 TJP2 AKAP13 BAG6 HSP90AB1	8.21e-06	503	117	10	16964243
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	PLEKHG2 ARHGAP4 FGD1 AKAP13	8.22e-06	38	117	4	11756498
Pubmed	N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso.	NCOR1 NCOR2 KDM4A	1.04e-05	13	117	3	14527417
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	MYO7A SPTAN1 SPTBN4	1.04e-05	13	117	3	18796539
Pubmed	CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.	NCOR1 NCOR2	1.12e-05	2	117	2	27733359
Pubmed	Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.	CACNA1C CACNA1D	1.12e-05	2	117	2	21054386
Pubmed	Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial-mesenchymal transition in lung endothelial cells.	NES NOTCH3	1.12e-05	2	117	2	37735673
Pubmed	Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes.	NCOR1 NCOR2	1.12e-05	2	117	2	22944139
Pubmed	An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.	CACNA1C CACNA1D	1.12e-05	2	117	2	24086669
Pubmed	Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.	NCOR1 NCOR2	1.12e-05	2	117	2	21131350
Pubmed	Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.	CACNA1C CACNA1D	1.12e-05	2	117	2	26049024
Pubmed	Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways.	NCOR1 NCOR2	1.12e-05	2	117	2	19299558
Pubmed	Unique forms of human and mouse nuclear receptor corepressor SMRT.	NCOR1 NCOR2	1.12e-05	2	117	2	10077563
Pubmed	Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.	CACNA1C CACNA1D	1.12e-05	2	117	2	19225208
Pubmed	Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.	CACNA1C CACNA1D	1.12e-05	2	117	2	16706838
Pubmed	Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.	CACNA1C CACNA1D	1.12e-05	2	117	2	23761887
Pubmed	Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.	CACNA1C CACNA1D	1.12e-05	2	117	2	14981074
Pubmed	Nomenclature for ion channel subunits.	CNGB1 CNGA4	1.12e-05	2	117	2	11764791
Pubmed	CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.	CACNA1C CACNA1D	1.12e-05	2	117	2	25292336
Pubmed	Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.	CACNA1C CACNA1D	1.12e-05	2	117	2	17526649
Pubmed	Ligand-activated signal transduction in the 2-cell embryo.	CACNA1C CACNA1D	1.12e-05	2	117	2	12606379
Pubmed	Nuclear Receptor Corepressors NCOR1 and SMRT Regulate Metabolism via Intestinal Regulation of Carbohydrate Transport.	NCOR1 NCOR2	1.12e-05	2	117	2	39106294
Pubmed	Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.	CACNA1C CACNA1D	1.12e-05	2	117	2	24941892
Pubmed	Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.	CACNA1C CACNA1D	1.12e-05	2	117	2	22826131
Pubmed	JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2).	NCOR1 KDM4A	1.12e-05	2	117	2	16024779
Pubmed	Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.	CACNA1C CACNA1D	1.12e-05	2	117	2	24470632
Pubmed	Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals.	NCOR1 NCOR2	1.12e-05	2	117	2	31208445
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.	CACNA1C CACNA1D	1.12e-05	2	117	2	24760982
Pubmed	Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.	CACNA1C CACNA1D	1.12e-05	2	117	2	20014384
Pubmed	NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming.	NCOR1 NCOR2	1.12e-05	2	117	2	29531310
Pubmed	Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.	CACNA1C CACNA1D	1.12e-05	2	117	2	30001160
Pubmed	Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.	CACNA1C CACNA1D	1.12e-05	2	117	2	21352396
Pubmed	Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.	CACNA1C CACNA1D	1.12e-05	2	117	2	17409250
Pubmed	Neuronal L-type calcium channels open quickly and are inhibited slowly.	CACNA1C CACNA1D	1.12e-05	2	117	2	16267232
Pubmed	Heterotrimeric G protein Gαs subunit attenuates PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, by direct interaction.	PLEKHG2 GNAS	1.12e-05	2	117	2	28108261
Pubmed	The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.	CACNA1C CACNA1D	1.12e-05	2	117	2	24996399
Pubmed	Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.	CACNA1C CACNA1D	1.12e-05	2	117	2	24849370
Pubmed	Regulation of corepressor alternative mRNA splicing by hormonal and metabolic signaling.	NCOR1 NCOR2	1.12e-05	2	117	2	26166430
Pubmed	Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.	CACNA1C CACNA1D	1.12e-05	2	117	2	17015854
Pubmed	Altered Gap Junction Network Topography in Mouse Models for Human Hereditary Deafness.	CACNA1D OTOF	1.12e-05	2	117	2	33036242
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.	CACNA1C CACNA1D	1.12e-05	2	117	2	24848473
Pubmed	Different CaV1.3 Channel Isoforms Control Distinct Components of the Synaptic Vesicle Cycle in Auditory Inner Hair Cells.	CACNA1D OTOF	1.12e-05	2	117	2	28193694
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	SPTAN1 NCOR2 RBSN CCSER2 CDC5L CCDC136	1.28e-05	151	117	6	17043677
Pubmed	NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.	PLEKHG2 ARHGAP4 FGD1 AKAP13	1.36e-05	43	117	4	12376548
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	SPTAN1 PBRM1 SF3B3 TJP2 EIF3A BAG6 HSP90AB1	1.55e-05	235	117	7	30258100
Pubmed	Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.	ARHGAP4 PBRM1 SF3B3 CDC5L PSPC1 HSP90AB1	1.71e-05	159	117	6	22751105
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	SPTAN1 NCAPH2 NCOR1 PBRM1 TSR1 HPS6 TPX2 HSP90AB1	1.75e-05	332	117	8	32786267
Pubmed	Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.	ZFC3H1 NCOR2 RBSN TSR1 CDC5L BAG6	1.83e-05	161	117	6	32572027
Pubmed	A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.	NCOR1 NCOR2 SF3B3	2.01e-05	16	117	3	11013263
Pubmed	Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.	CALCOCO1 NCOR1 NCOR2	2.44e-05	17	117	3	19183483
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	NES PUF60 SF3B3 TJP2 CDC5L CNGB1	2.49e-05	170	117	6	16159877
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	FKBP15 HECTD4 ZBED4 GIGYF2 KDM4A	2.54e-05	102	117	5	9734811
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	L3MBTL2 RBBP6 NCAPH2 ZFC3H1 NCOR1 NCOR2 RCOR1 PBRM1 SF3B3 ZBED4 NFIL3 TPX2 CIZ1 UTP20 CDC5L	3.02e-05	1294	117	15	30804502
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	PCNP RBBP6 TASOR2 NCBP3 RCOR1 PBRM1 TPX2 CDC5L BAG6	3.12e-05	469	117	9	27634302
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RBBP6 CALCOCO1 ZFC3H1 SPTBN4 OTOF TJP2 AKAP13 EIF3A	3.18e-05	361	117	8	26167880
Pubmed	Functional proteomics mapping of a human signaling pathway.	STAG1 RBBP6 CREBZF NCOR1 NCOR2 RNF123 PBRM1 SUSD1 HERC1 BAG6	3.26e-05	591	117	10	15231748
Pubmed	Characterization of the interaction between protein 4.1R and ZO-2. A possible link between the tight junction and the actin cytoskeleton.	SPTAN1 TJP2	3.36e-05	3	117	2	10874042
Pubmed	Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus.	NCOR1 NCOR2	3.36e-05	3	117	2	16030140
Pubmed	Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor.	NCOR1 NCOR2	3.36e-05	3	117	2	19098224
Pubmed	The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor.	NCOR1 NCOR2	3.36e-05	3	117	2	16373395
Pubmed	Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.	NCOR1 NCOR2	3.36e-05	3	117	2	31404087
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1D	3.36e-05	3	117	2	17767505
Pubmed	Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo.	NCOR1 NCOR2	3.36e-05	3	117	2	23292142
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1D	3.36e-05	3	117	2	2173707
Pubmed	Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.	NCOR1 NCOR2	3.36e-05	3	117	2	24268577
Pubmed	Oligomerization of ETO is obligatory for corepressor interaction.	NCOR1 NCOR2	3.36e-05	3	117	2	11113190
Pubmed	EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding.	NCOR1 NCOR2	3.36e-05	3	117	2	21518914
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1C CACNA1D	3.36e-05	3	117	2	26831068
Pubmed	Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT.	NCOR1 NCOR2	3.36e-05	3	117	2	15802375
Pubmed	JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5.	CHD5 KDM4A	3.36e-05	3	117	2	23168260
Pubmed	Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3.	PLEKHG2 GNAS	3.36e-05	3	117	2	28489964
Pubmed	SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling.	NCOR1 NCOR2	3.36e-05	3	117	2	36238311
Pubmed	A synaptic F-actin network controls otoferlin-dependent exocytosis in auditory inner hair cells.	CACNA1D OTOF	3.36e-05	3	117	2	26568308
Pubmed	Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.	CACNA1C CACNA1D	3.36e-05	3	117	2	23338940
Interaction	FBXO22 interactions	BDP1 CACNA1C HGH1 MYO7A CT47A1 NCBP3 NCOR1 NCOR2 SHPRH TJP2 GIGYF2 KDM4A HERC1 BAG6	2.48e-06	540	115	14	int:FBXO22
Interaction	NUP43 interactions	LRP12 L3MBTL2 SZT2 RBBP6 ZFC3H1 TASOR2 NCBP3 NCOR1 NCOR2 PBRM1 CCSER2 CIZ1 UTP20 SLX4 HSP90AB1	2.73e-06	625	115	15	int:NUP43
Interaction	NCOR1 interactions	KLF15 NCAPH2 HDAC7 NCOR1 NCOR2 RCOR1 SF3B3 KDM4A EIF3A IL17RA SLX4	7.44e-06	363	115	11	int:NCOR1
Interaction	SNAI3 interactions	STRIP1 RNF123 TJP2	9.93e-06	8	115	3	int:SNAI3
Interaction	AR interactions	MAGEA2 PUF60 HECTD4 HDAC7 NCOR1 NCOR2 RCOR1 PBRM1 SF3B3 SUGP2 HPS6 TPX2 KDM4A GNAS CDC5L PSPC1 BAG6 HSP90AB1	1.28e-05	992	115	18	int:AR
Interaction	SPDL1 interactions	SPTAN1 RCOR1 PBRM1 SF3B3 TJP2 EIF3A SYVN1 BAG6 SLX4 HSP90AB1	1.32e-05	315	115	10	int:SPDL1
Interaction	KIF20A interactions	NES RBBP6 PUF60 SPTAN1 MCF2L2 HECTD4 SPTBN4 SF3B3 SUGP2 FER1L4 TPX2 TJP2 GIGYF2 PPIP5K1 EIF3A GNAS HERC1 HSP90AB1	2.79e-05	1052	115	18	int:KIF20A
Interaction	GLRA2 interactions	LRP12 EXTL3 SYVN1 BAG6	2.81e-05	31	115	4	int:GLRA2
Interaction	BCOR interactions	L3MBTL2 KLF15 NCAPH2 NCOR1 NCOR2 RCOR1 SUGP2 IL17RA SLX4	5.93e-05	302	115	9	int:BCOR
Interaction	SCARNA22 interactions	ARHGAP4 PBRM1 SF3B3 CDC5L PSPC1 HSP90AB1	5.93e-05	118	115	6	int:SCARNA22
Interaction	SMARCC1 interactions	L3MBTL2 SPTAN1 NCAPH2 STRIP1 NCOR1 RCOR1 PBRM1 SF3B3 TSR1 SLX4	7.08e-05	384	115	10	int:SMARCC1
Interaction	MIR429 interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	7.42e-05	76	115	5	int:MIR429
Interaction	CRISP2 interactions	P3H4 RNF123 TMEM132A IL17RA	7.85e-05	40	115	4	int:CRISP2
Interaction	TOP3B interactions	SZT2 MYO7A PUF60 SPTAN1 HECTD4 EXTL3 STK32C HDAC7 NCOR1 NCOR2 ZBED4 CLCN7 SUGP2 CHD5 HPS6 TMEM132A AKAP13 KDM4A GNAS HERC1 SYVN1	7.94e-05	1470	115	21	int:TOP3B
Interaction	CCDC85C interactions	EXTL3 PPP1R7 RCOR1 OTOF TJP2 CCDC136	8.18e-05	125	115	6	int:CCDC85C
Interaction	NPAS1 interactions	NES ARHGAP4 NCOR2 HPS6 GIGYF2 HERC1 DNAJB5 HSP90AB1	8.22e-05	245	115	8	int:NPAS1
Interaction	CHD4 interactions	L3MBTL2 RBBP6 PUF60 SPTAN1 NCBP3 RCOR1 PBRM1 SF3B3 SUGP2 TSR1 CHD5 SHPRH GIGYF2 EIF3A CDC5L SLX4	8.46e-05	938	115	16	int:CHD4
Interaction	DHX40 interactions	RBBP6 ZFC3H1 TASOR2 NCBP3 UTP20 CDC5L HERC1 SLX4	9.20e-05	249	115	8	int:DHX40
Interaction	GLDC interactions	RBBP6 SPTAN1 NCBP3 SF3B3 SUGP2 TJP2 GIGYF2 EIF3A HSP90AB1	9.46e-05	321	115	9	int:GLDC
Interaction	MIR143 interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	9.48e-05	80	115	5	int:MIR143
Interaction	AHR interactions	CALCOCO1 NCOR2 RNF123 PBRM1 SF3B3 HSP90AB1	1.11e-04	132	115	6	int:AHR
Interaction	TBL1XR1 interactions	SPTAN1 NCAPH2 HDAC7 NCOR1 NCOR2 RCOR1 IL17RA	1.18e-04	192	115	7	int:TBL1XR1
Interaction	MIR107 interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	1.26e-04	85	115	5	int:MIR107
Interaction	BCORL1 interactions	L3MBTL2 KLF15 HDAC7 RCOR1 RNF123	1.26e-04	85	115	5	int:BCORL1
Interaction	IQGAP3 interactions	NCAPH2 STK32C SF3B3 IL17RA HERC1 SLX4	1.59e-04	141	115	6	int:IQGAP3
Interaction	ZBTB5 interactions	NCOR1 NCOR2 RCOR1 SLX4	1.75e-04	49	115	4	int:ZBTB5
Interaction	SMC5 interactions	RBBP6 PUF60 HDAC7 TASOR2 NCBP3 NCOR1 NCOR2 SF3B3 SUGP2 TPX2 CIZ1 GIGYF2 CDC5L PSPC1 SLX4 HSP90AB1	1.77e-04	1000	115	16	int:SMC5
Interaction	OBSL1 interactions	NES PUF60 TASOR2 NCBP3 FBXW8 PBRM1 SF3B3 SUGP2 CIZ1 TJP2 UTP20 EIF3A CDC5L PSPC1 HSP90AB1	1.89e-04	902	115	15	int:OBSL1
Interaction	STIP1 interactions	PUF60 SPTAN1 LRRK2 STK32C WDFY4 RNF123 SF3B3 SUGP2 ARHGEF10 MAP4K1 EIF3A CDC5L DNAJB5 BAG6 HSP90AB1 HSP90AB3P	1.89e-04	1006	115	16	int:STIP1
Interaction	CIT interactions	NES STAG1 RBBP6 PUF60 SPTAN1 LRRK2 SPTBN4 SF3B3 SUGP2 TSR1 TPX2 TJP2 UTP20 EIF3A GNAS CDC5L HERC1 PSPC1 HSP90AB1 HSP90AB3P	1.93e-04	1450	115	20	int:CIT
Interaction	MIR214 interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	1.93e-04	93	115	5	int:MIR214
Interaction	TTF2 interactions	HDAC7 TJP2 IL17RA CDC5L MRFAP1L1 HSP90AB1	1.99e-04	147	115	6	int:TTF2
Interaction	LINC02910 interactions	ZFC3H1 NCBP3 TJP2 GIGYF2 CDC5L	2.13e-04	95	115	5	int:LINC02910
Interaction	EIF3H interactions	BDP1 PUF60 ANGEL1 KLF15 EIF3A PSPC1 BAG6 HSP90AB1	2.16e-04	282	115	8	int:EIF3H
Interaction	MTA1 interactions	STAG1 L3MBTL2 LRRK2 RCOR1 CHD5 SHPRH AKAP13 BAG6	2.21e-04	283	115	8	int:MTA1
Interaction	C1orf87 interactions	FKBP15 LRRK2 HERC1	2.23e-04	21	115	3	int:C1orf87
Interaction	MIR363 interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	2.35e-04	97	115	5	int:MIR363
Interaction	KBTBD7 interactions	L3MBTL2 KLF15 FOXN3 TSR1 PI4KB TJP2 SLX4	2.36e-04	215	115	7	int:KBTBD7
Interaction	ADAR interactions	STAG1 PUF60 ZFC3H1 TASOR2 SF3B3 CHD5 PSPC1 SLX4	2.38e-04	286	115	8	int:ADAR
Interaction	MEN1 interactions	PCNP STAG1 RBBP6 FOXN3 ZFC3H1 NCBP3 NCOR1 PBRM1 SUGP2 TSR1 TPX2 TJP2 GIGYF2 UTP20 EIF3A PSPC1	2.44e-04	1029	115	16	int:MEN1
Interaction	MIR106B interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	2.47e-04	98	115	5	int:MIR106B
Interaction	RPA4 interactions	PCNP SPTAN1 NCOR1 RBSN SUGP2 TPX2 TJP2 CDC5L PSPC1 SLX4	2.67e-04	452	115	10	int:RPA4
Interaction	MIR19A interactions	RBBP6 PUF60 SF3B3 SUGP2 UTP20	2.71e-04	100	115	5	int:MIR19A
Interaction	MIRLET7D interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	2.84e-04	101	115	5	int:MIRLET7D
Interaction	MIR25 interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	2.84e-04	101	115	5	int:MIR25
Interaction	FBXW8 interactions	PCNP RBBP6 ZFC3H1 FBXW8 MAP4K1 FER1L4	2.84e-04	157	115	6	int:FBXW8
Interaction	C1D interactions	ZFC3H1 NCOR1 NCOR2 GIGYF2	2.94e-04	56	115	4	int:C1D
Interaction	EIF1B interactions	TSR1 TJP2 EIF3A PSPC1	2.94e-04	56	115	4	int:EIF1B
Interaction	ERG interactions	PUF60 SPTAN1 NCOR1 NCOR2 SF3B3 CDC5L SLX4	2.95e-04	223	115	7	int:ERG
Interaction	CCDC88A interactions	NES WDFY4 RCOR1 ARHGEF10 IL17RA BAG6 CCDC136	3.19e-04	226	115	7	int:CCDC88A
Interaction	TERF2IP interactions	PCNP RBBP6 PUF60 TASOR2 NCOR1 NCOR2 RCOR1 SUGP2 TPX2 CIZ1 SLX4	3.21e-04	552	115	11	int:TERF2IP
Interaction	HULC interactions	ZFC3H1 NCOR2 RBSN TSR1 CDC5L BAG6	3.25e-04	161	115	6	int:HULC
Interaction	MIR19B1 interactions	RBBP6 PUF60 SF3B3 SUGP2 UTP20	3.25e-04	104	115	5	int:MIR19B1
Interaction	STK25 interactions	LRRK2 STRIP1 CLCN7 PDCD10 HSP90AB1	3.25e-04	104	115	5	int:STK25
Interaction	HDAC4 interactions	CACNA1C STAG1 SPTAN1 HDAC7 NCOR1 NCOR2 PBRM1 GIGYF2 CDC5L DNAJB5 PDCD10 CCDC136 HSP90AB1	3.26e-04	744	115	13	int:HDAC4
Interaction	DDX46 interactions	PUF60 RCOR1 SF3B3 TPX2 CDC5L SLX4 HSP90AB1	3.28e-04	227	115	7	int:DDX46
Interaction	MYBL2 interactions	KLF15 NCOR1 NCOR2 CHD5 SHPRH SLX4	3.36e-04	162	115	6	int:MYBL2
Interaction	TNIK interactions	FKBP15 NES SPTAN1 CALCOCO1 STRIP1 NCOR2 RCOR1 PI4KB CDC5L	3.39e-04	381	115	9	int:TNIK
Interaction	SF3B3 interactions	STAG1 PUF60 SPTAN1 WDFY4 NCOR1 SF3B3 ARHGEF10 HPS6 PPIP5K1 CDC5L SLX4	3.52e-04	558	115	11	int:SF3B3
Interaction	MIRLET7E interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	3.55e-04	106	115	5	int:MIRLET7E
Interaction	CCDC185 interactions	MAGEA2 ZBED4 CDC5L CCDC136	3.84e-04	60	115	4	int:CCDC185
Interaction	HTR3A interactions	LRP12 PLPPR3 EXTL3 SYVN1 PIGO	3.87e-04	108	115	5	int:HTR3A
Interaction	STK24 interactions	LRRK2 STRIP1 PI4KB TJP2 CDC5L PDCD10	4.08e-04	168	115	6	int:STK24
Interaction	RPS25 interactions	HECTD4 WDFY4 RNF123 TSR1 SHPRH EIF3A CDC5L DNAJB5 PSPC1	4.17e-04	392	115	9	int:RPS25
Interaction	NCAPH2 interactions	WDR55 NCAPH2 TASOR2 NCOR1 GIGYF2 SLX4	4.21e-04	169	115	6	int:NCAPH2
Interaction	MIR34B interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	4.21e-04	110	115	5	int:MIR34B
Interaction	PRC1 interactions	BDP1 NES RBBP6 PUF60 SPTAN1 SPTBN4 PBRM1 SF3B3 CHD5 TPX2 UTP20 GNAS CDC5L HERC1 HSP90AB1	4.24e-04	973	115	15	int:PRC1
Interaction	DUSP16 interactions	SZT2 TASOR2 RNF123 GIGYF2 PPIP5K1 EIF3A DNAJB5	4.25e-04	237	115	7	int:DUSP16
Interaction	HDAC3 interactions	MAGEA2 L3MBTL2 HDAC7 NCOR1 NCOR2 RCOR1 KDM4A IL17RA	4.35e-04	313	115	8	int:HDAC3
Interaction	DOCK5 interactions	SZT2 FBXW8 RNF123 CDC5L HSP90AB1	4.39e-04	111	115	5	int:DOCK5
Interaction	USP7 interactions	PCNP CACNA1C MYO7B SPTAN1 LRRK2 PPP1R7 PBRM1 SF3B3 CLCN5 OTOF TPX2 ZFHX2 GIGYF2 PPIP5K1 CDC5L HERC1 SYVN1 BAG6	4.51e-04	1313	115	18	int:USP7
Interaction	AQP7 interactions	MFSD6 CLCN7	4.77e-04	6	115	2	int:AQP7
Interaction	FER1L4 interactions	FBXW8 FER1L4	4.77e-04	6	115	2	int:FER1L4
Interaction	MIRLET7I interactions	PUF60 SF3B3 SUGP2 UTP20 CDC5L	4.96e-04	114	115	5	int:MIRLET7I
Interaction	EED interactions	STAG1 L3MBTL2 SZT2 RBBP6 PUF60 SPTAN1 TASOR2 PPP1R7 NCOR1 PBRM1 SF3B3 SHPRH TJP2 UTP20 EIF3A CDC5L PSPC1 BAG6 HSP90AB1	5.17e-04	1445	115	19	int:EED
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	BDP1 NCOR1 NCOR2 RCOR1 CDC5L	3.86e-06	53	81	5	532
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	MCF2L2 PLEKHG2 ARHGEF10 FGD1 AKAP13	1.15e-05	66	81	5	722
GeneFamily	A-kinase anchoring proteins\|Myosins, class VII\|Deafness associated genes\|FERM domain containing	MYO7A MYO7B	1.98e-05	2	81	2	1102
GeneFamily	Ferlin family	OTOF FER1L4	2.94e-04	6	81	2	828
GeneFamily	EF-hand domain containing\|Spectrins	SPTAN1 SPTBN4	4.10e-04	7	81	2	1113
GeneFamily	Cyclic nucleotide gated channels	CNGB1 CNGA4	8.72e-04	10	81	2	250
GeneFamily	Chloride voltage-gated channels	CLCN5 CLCN7	8.72e-04	10	81	2	302
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STRIP1 PDCD10	3.57e-03	20	81	2	1371
GeneFamily	Ataxins\|Trinucleotide repeat containing	NCOR2 GIGYF2	5.56e-03	25	81	2	775
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1D	6.01e-03	26	81	2	253
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	MYO7A AKAP13	7.44e-03	29	81	2	396
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	RBSN FGD1	8.47e-03	31	81	2	81
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	FKBP15 PPP1R7 NCOR1 CLCN7	8.89e-03	181	81	4	694
Drug	Oxolinic acid [14698-29-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	LRP12 SZT2 FOXN3 P3H4 CLCN5 SUGP2 AKAP13 IL17RA NOTCH3	6.43e-07	196	114	9	2103_DN
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	CACNA1D RBBP6 FOXN3 CLCN5 ZBED4 CLCN7 CDC5L ZNF282	5.46e-06	191	114	8	6839_DN
Drug	Norfloxacin [70458-96-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A	SPTAN1 NCAPH2 CREBZF PPP1R7 NCOR1 CLCN5 CLCN7 SUGP2	5.89e-06	193	114	8	5985_DN
Drug	Pyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; HL60; HG-U133A	RBBP6 NCAPH2 IRGQ ARHGAP4 NCOR1 RNF123 CLCN7 CIZ1	6.12e-06	194	114	8	1759_UP
Drug	Cholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A	LRP12 FOXN3 HDAC7 CREBZF ARHGAP4 ZFHX2 IL17RA ZNF282	6.36e-06	195	114	8	3298_UP
Drug	0179445-0000 [211246-22-9]; Down 200; 1uM; MCF7; HT_HG-U133A	CACNA1D EXTL3 HDAC7 CLCN7 SUGP2 ARHGEF10 CIZ1 PIGO	6.60e-06	196	114	8	3633_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	LRP12 SPTAN1 PPP1R7 ZBED4 TSR1 CCSER2 UTP20 CDC5L	6.60e-06	196	114	8	1001_DN
Drug	Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A	TSNAXIP1 SZT2 NCAPH2 FOXN3 EXTL3 HDAC7 UTP20 AKAP13	6.60e-06	196	114	8	4359_DN
Drug	telL	CREBZF NCOR1 NCOR2 RCOR1	6.95e-06	25	114	4	CID000101525
Drug	Flecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	NCAPH2 EXTL3 P3H4 RNF123 CLCN7 HPS6 CIZ1 FGD1	7.11e-06	198	114	8	3843_DN
Drug	Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; HL60; HT_HG-U133A	SPTAN1 NCAPH2 HDAC7 ARHGEF10 MAP4K1 CHD5 GNAS DNAJB5	7.11e-06	198	114	8	3012_DN
Drug	Spiperone [749-02-0]; Down 200; 10.2uM; HL60; HG-U133A	STAG1 NCAPH2 CREBZF CLCN7 TSR1 CIZ1 TJP2 EIF3A	7.38e-06	199	114	8	1559_DN
Drug	thalicarpine	NCOR1 NCOR2 GML AKAP13	1.92e-05	32	114	4	CID000021470
Drug	Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A	LRP12 SPTAN1 WDR55 NCAPH2 CLCN7 ZFHX2 PIGO	4.73e-05	189	114	7	3371_DN
Drug	Benzydamine hydrochloride [132-69-4]; Down 200; 11.6uM; HL60; HG-U133A	LRP12 ANGEL1 IRGQ SUGP2 TSR1 CIZ1 TJP2	5.58e-05	194	114	7	1552_DN
Drug	Hemicholinium bromide [312-45-8]; Down 200; 7uM; PC3; HT_HG-U133A	TSNAXIP1 SPTAN1 NCAPH2 PPP1R7 SUGP2 HPS6 DNAJB5	5.77e-05	195	114	7	6739_DN
Drug	Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A	CACNA1D LRP12 CREBZF PPP1R7 FGD1 ZNF282 PIGO	5.95e-05	196	114	7	1512_DN
Drug	Calycanthine [595-05-1]; Down 200; 11.6uM; HL60; HG-U133A	STAG1 SPTAN1 NCOR1 TSR1 CIZ1 CDC5L MRFAP1L1	5.95e-05	196	114	7	1771_DN
Drug	Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A	SPTAN1 NCAPH2 EXTL3 HDAC7 PPP1R7 NCOR1 CLCN7	5.95e-05	196	114	7	6844_DN
Drug	Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A	NCAPH2 EXTL3 ARHGAP4 CLCN7 CHD5 CIZ1 ZFHX2	5.95e-05	196	114	7	6061_UP
Drug	Iopromide [73334-07-3]; Up 200; 5uM; PC3; HT_HG-U133A	TSNAXIP1 MYO7A NCAPH2 HDAC7 NCOR2 CLCN5 ARHGEF10	6.15e-05	197	114	7	4504_UP
Drug	Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; PC3; HT_HG-U133A	LRP12 WDR55 NCAPH2 HPS6 TMEM132A AKAP13 IL17RA	6.15e-05	197	114	7	6326_DN
Drug	Norethindrone [68-22-4]; Down 200; 13.4uM; PC3; HT_HG-U133A	SPTAN1 MFSD6 EXTL3 HDAC7 TMEM132A FGD1 NOTCH3	6.15e-05	197	114	7	5055_DN
Drug	Urapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; MCF7; HT_HG-U133A	NES CALCOCO1 NCAPH2 TSR1 HPS6 CIZ1 PIGO	6.15e-05	197	114	7	6455_DN
Drug	Gramine [87-52-5]; Down 200; 23uM; PC3; HT_HG-U133A	TSNAXIP1 NCAPH2 FOXN3 PPP1R7 CLCN5 CLCN7 DNAJB5	6.15e-05	197	114	7	3999_DN
Drug	Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; HL60; HT_HG-U133A	NCAPH2 HDAC7 CLCN7 ARHGEF10 CHD5 GNAS DNAJB5	6.15e-05	197	114	7	3009_DN
Drug	Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A	CACNA1D KLF15 NCAPH2 EXTL3 CHD5 GNAS NOTCH3	6.15e-05	197	114	7	3525_UP
Drug	Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	NCAPH2 FOXN3 NCOR1 CLCN5 CLCN7 TSR1 FGD1	6.15e-05	197	114	7	1468_DN
Drug	Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A	SPTAN1 NCAPH2 EXTL3 CREBZF CLCN5 DNAJB5 NOTCH3	6.35e-05	198	114	7	2320_DN
Drug	Bemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A	MFSD6 HDAC7 CLCN7 SUGP2 FGD1 GNAS NOTCH3	6.35e-05	198	114	7	6668_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	CACNA1D NCAPH2 FOXN3 CREBZF NCOR2 ZBED4 AKAP13	6.35e-05	198	114	7	4729_DN
Drug	Pepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A	CACNA1D FKBP15 NCAPH2 RNF123 CLCN7 AKAP13 IL17RA	6.35e-05	198	114	7	3264_DN
Drug	Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A	CACNA1D LRP12 SPTAN1 HDAC7 SPTBN4 CIZ1 CNGB1	6.35e-05	198	114	7	3548_UP
Drug	Sulfasalazine [599-79-1]; Down 200; 10uM; HL60; HG-U133A	WDR55 NCAPH2 PPP1R7 ZBED4 ARHGEF10 TPX2 AKAP13	6.55e-05	199	114	7	1733_DN
Drug	Dichlorphenamide [120-97-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A	SPTAN1 NCAPH2 PPP1R7 SUGP2 TSR1 PI4KB IL17RA	6.55e-05	199	114	7	5286_UP
Drug	Sulfabenzamide [127-71-9]; Down 200; 14.4uM; PC3; HT_HG-U133A	FKBP15 SPTAN1 PPP1R7 NCOR2 ZBED4 CLCN7 PIGO	6.55e-05	199	114	7	6634_DN
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A	MFSD6 NCAPH2 HDAC7 NCBP3 CLCN5 FGD1 DNAJB5	6.55e-05	199	114	7	4543_DN
Drug	Vitexin [3681-93-4]; Down 200; 9.2uM; MCF7; HT_HG-U133A	LRP12 SZT2 CREBZF CLCN5 FGD1 DNAJB5 NOTCH3	6.76e-05	200	114	7	4413_DN
Drug	Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A	CACNA1D SPTAN1 FOXN3 EXTL3 HDAC7 NCOR1 SUGP2	6.76e-05	200	114	7	6829_DN
Drug	NSC-686960	CACNA1C CACNA1D	1.48e-04	4	114	2	CID000192816
Drug	halofenate	NCOR1 NCOR2	1.48e-04	4	114	2	CID000033584
Drug	procyanidin C1	CALCOCO1 GNAS	1.48e-04	4	114	2	CID000169853
Drug	Nisoldipine	CACNA1C CACNA1D	2.46e-04	5	114	2	DB00401
Drug	B 874-67	CACNA1C CACNA1D	2.46e-04	5	114	2	CID000195466
Drug	nemadipine-A	CACNA1C CACNA1D	2.46e-04	5	114	2	CID002856102
Drug	Nilvadipine	CACNA1C CACNA1D	2.46e-04	5	114	2	DB06712
Drug	methyl beta-aminocrotonate	CACNA1C CACNA1D	2.46e-04	5	114	2	CID000084253
Drug	Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; HL60; HG-U133A	SPTAN1 IRGQ ARHGAP4 CLCN7 CIZ1 AKAP13	2.96e-04	180	114	6	1752_UP
Drug	CPU-23	CACNA1C CACNA1D	3.68e-04	6	114	2	CID003036051
Drug	Propofol [2078-54-8]; Down 200; 22.4uM; MCF7; HT_HG-U133A	CACNA1D LRP12 WDR55 SUGP2 ZFHX2 PIGO	4.06e-04	191	114	6	3386_DN
Drug	Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A	NES NCAPH2 NCOR1 HPS6 UTP20 CDC5L	4.17e-04	192	114	6	6207_DN
Drug	clozapine; Down 200; 10uM; HL60; HT_HG-U133A	SZT2 MYO7A CALCOCO1 CLCN7 PI4KB PIGO	4.17e-04	192	114	6	6188_DN
Drug	Astemizole [68844-77-9]; Down 200; 8.8uM; PC3; HT_HG-U133A	LRP12 IRGQ P3H4 HPS6 GNAS CDC5L	4.29e-04	193	114	6	2049_DN
Drug	Diethylstilbestrol [56-53-1]; Down 200; 15uM; HL60; HT_HG-U133A	SPTAN1 ANGEL1 FOXN3 CLCN7 CCSER2 PIGO	4.29e-04	193	114	6	2567_DN
Drug	Captopril [62571-86-2]; Up 200; 17.2uM; HL60; HG-U133A	SPTAN1 NCAPH2 FOXN3 PPP1R7 ARHGAP4 EIF3A	4.29e-04	193	114	6	1988_UP
Drug	Progesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A	SPTAN1 NCAPH2 EXTL3 HDAC7 CCSER2 PIGO	4.29e-04	193	114	6	6646_DN
Drug	Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A	LRP12 ZBED4 SUGP2 CCSER2 KDM4A PIGO	4.41e-04	194	114	6	7214_DN
Drug	Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A	WDR55 TSR1 PI4KB CIZ1 IL17RA PIGO	4.41e-04	194	114	6	4838_UP
Drug	Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT_HG-U133A	TSNAXIP1 EXTL3 HDAC7 ARHGAP4 HPS6 NOTCH3	4.41e-04	194	114	6	3526_UP
Drug	Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; MCF7; HT_HG-U133A	NES NCAPH2 EXTL3 ZBED4 CLCN7 IL17RA	4.41e-04	194	114	6	6832_DN
Drug	Dirithromycin [62013-04-1]; Down 200; 4.8uM; HL60; HG-U133A	ANGEL1 IRGQ ARHGEF10 CIZ1 AKAP13 EIF3A	4.41e-04	194	114	6	1712_DN
Drug	(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A	IRGQ HDAC7 SF3B3 TMEM132A CCSER2 AKAP13	4.41e-04	194	114	6	4524_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	FKBP15 NCAPH2 EXTL3 PPP1R7 IL17RA PIGO	4.41e-04	194	114	6	5221_DN
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; HL60; HG-U133A	CREBZF NCOR1 TSR1 CIZ1 TJP2 EIF3A	4.41e-04	194	114	6	1715_DN
Drug	17-AAG; Down 200; 1uM; HL60; HT_HG-U133A	RBBP6 PPP1R7 ZBED4 PI4KB CCSER2 GNAS	4.41e-04	194	114	6	1147_DN
Drug	Alexidine dihydrochloride [22573-93-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A	LRP12 FOXN3 CLCN5 ARHGEF10 IL17RA CDC5L	4.41e-04	194	114	6	4721_DN
Drug	Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; HL60; HT_HG-U133A	SZT2 ANGEL1 NCAPH2 SF3B3 SUGP2 PIGO	4.53e-04	195	114	6	1866_DN
Drug	Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; MCF7; HT_HG-U133A	LRP12 CALCOCO1 ZBED4 SUGP2 TMEM132A AKAP13	4.53e-04	195	114	6	2826_DN
Drug	Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; PC3; HT_HG-U133A	SPTAN1 NCAPH2 FOXN3 ARHGEF10 HPS6 IL17RA	4.53e-04	195	114	6	7394_UP
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A	CACNA1D SPTAN1 NCAPH2 EXTL3 CLCN5 TSR1	4.53e-04	195	114	6	1665_DN
Drug	novobiocin sodium, USP; Down 200; 100uM; SKMEL5; HG-U133A	RBBP6 ANGEL1 EXTL3 SF3B3 TMEM132A CIZ1	4.53e-04	195	114	6	632_DN
Drug	PHA-00816795 [212631-79-3]; Up 200; 10uM; PC3; HT_HG-U133A	SPTAN1 ANGEL1 NCAPH2 HDAC7 RNF123 IL17RA	4.53e-04	195	114	6	7072_UP
Drug	Sulfaphenazole [526-08-9]; Down 200; 12.8uM; PC3; HT_HG-U133A	P3H4 PI4KB AKAP13 IL17RA HERC1 PIGO	4.65e-04	196	114	6	1794_DN
Drug	Pepstatin A [26305-03-3]; Down 200; 5.8uM; PC3; HT_HG-U133A	FKBP15 EXTL3 ARHGEF10 PI4KB DNAJB5 NOTCH3	4.65e-04	196	114	6	4206_DN
Drug	Debrisoquin sulfate [581-88-4]; Up 200; 9uM; MCF7; HT_HG-U133A	SPTAN1 FOXN3 P3H4 NCOR1 NCOR2 CLCN7	4.65e-04	196	114	6	5288_UP
Drug	Ursolic acid [77-52-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A	NCAPH2 FOXN3 PPP1R7 RNF123 CIZ1 PIGO	4.65e-04	196	114	6	7181_DN
Drug	Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; HL60; HT_HG-U133A	LRP12 SPTAN1 ZBED4 CLCN7 SUGP2 CIZ1	4.65e-04	196	114	6	1841_DN
Drug	Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A	CACNA1D FOXN3 EXTL3 CREBZF CLCN7 ZFHX2	4.65e-04	196	114	6	3435_UP
Drug	Aceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A	NCAPH2 NCOR2 ARHGEF10 AKAP13 IL17RA NOTCH3	4.65e-04	196	114	6	7269_UP
Drug	Benzthiazide [91-33-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A	FKBP15 NCAPH2 FOXN3 RNF123 FGD1 CDC5L	4.65e-04	196	114	6	3329_DN
Drug	Chrysene-1,4-quinone [100900-16-1]; Down 200; 15.4uM; PC3; HT_HG-U133A	IRGQ CREBZF NCOR1 ARHGEF10 PI4KB AKAP13	4.65e-04	196	114	6	7139_DN
Drug	Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A	CREBZF NCOR1 CLCN7 FGD1 IL17RA ZNF282	4.65e-04	196	114	6	2751_DN
Drug	Cefaclor [70356-03-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A	FKBP15 NCAPH2 CREBZF RNF123 CLCN7 HPS6	4.65e-04	196	114	6	2843_DN
Drug	2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A_EA	NCAPH2 NCOR1 RNF123 PI4KB ZNF282 NOTCH3	4.65e-04	196	114	6	1002_DN
Drug	Probucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	CACNA1D LRP12 PI4KB GNAS PIGO NOTCH3	4.65e-04	196	114	6	5261_DN
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	LRP12 PPP1R7 CLCN7 HPS6 CDC5L PIGO	4.65e-04	196	114	6	3613_DN
Drug	Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; PC3; HT_HG-U133A	FKBP15 NCAPH2 EXTL3 P3H4 TMEM132A AKAP13	4.65e-04	196	114	6	7367_DN
Drug	Haloperidol [52-86-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A	NCAPH2 CREBZF PPP1R7 SUGP2 ARHGEF10 FGD1	4.65e-04	196	114	6	1539_DN
Drug	Iobenguane sulfate; Down 200; 10.8uM; HL60; HG-U133A	ANGEL1 IRGQ ZBED4 CLCN7 TSR1 AKAP13	4.65e-04	196	114	6	1729_DN
Drug	S-(+)-ibuprofen [51146-56-6]; Down 200; 19.4uM; MCF7; HT_HG-U133A	EXTL3 SF3B3 SUGP2 TMEM132A AKAP13 IL17RA	4.65e-04	196	114	6	6471_DN
Drug	chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A	FKBP15 SPTAN1 CREBZF CLCN7 ZFHX2 AKAP13	4.65e-04	196	114	6	5577_DN
Drug	Cortisone [53-06-5]; Up 200; 11uM; MCF7; HT_HG-U133A	CACNA1D NCAPH2 FOXN3 ARHGEF10 CNGB1 PIGO	4.78e-04	197	114	6	7458_UP
Drug	Etofylline [519-37-9]; Down 200; 17.8uM; PC3; HT_HG-U133A	CALCOCO1 NCAPH2 P3H4 SF3B3 TSR1 IL17RA	4.78e-04	197	114	6	2093_DN
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A	LRP12 WDR55 NCAPH2 CLCN7 AKAP13 IL17RA	4.78e-04	197	114	6	6012_DN
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A	SZT2 NCAPH2 HDAC7 NCOR2 ZFHX2 AKAP13	4.78e-04	197	114	6	5276_UP
Drug	Cytisine (-) [485-35-8]; Down 200; 21uM; MCF7; HT_HG-U133A	SPTAN1 NCAPH2 CLCN5 AKAP13 IL17RA NOTCH3	4.78e-04	197	114	6	6217_DN
Drug	Epirizole [18694-40-1]; Down 200; 17uM; PC3; HT_HG-U133A	NCAPH2 HDAC7 FGD1 AKAP13 ZNF282 PIGO	4.78e-04	197	114	6	1803_DN
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A	CALCOCO1 IRGQ PI4KB CIZ1 AKAP13 NOTCH3	4.78e-04	197	114	6	3415_DN
Drug	Myricetin [529-44-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	CACNA1D SPTAN1 CALCOCO1 CREBZF CLCN7 FGD1	4.78e-04	197	114	6	3270_DN
Drug	Alverine citrate salt [5560-59-8]; Up 200; 8.4uM; PC3; HT_HG-U133A	TSNAXIP1 MYO7A MFSD6 PPP1R7 ZFHX2 DNAJB5	4.78e-04	197	114	6	2110_UP
Disease	hypertension	CACNA1D SZT2 LRRC10B HECTD4 NCOR2 PBRM1 GML KDM4A BAG6	2.02e-06	307	108	9	EFO_0000537
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1D	7.93e-05	4	108	2	DOID:0060173 (implicated_via_orthology)
Disease	Agents acting on the renin-angiotensin system use measurement	CACNA1C CACNA1D LRRC10B HDAC7 SF3B3 TJP2 GML	2.39e-04	335	108	7	EFO_0009931
Disease	osteopetrosis (implicated_via_orthology)	CLCN5 CLCN7	2.75e-04	7	108	2	DOID:13533 (implicated_via_orthology)
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	OTOF FER1L4	2.75e-04	7	108	2	DOID:11724 (implicated_via_orthology)
Disease	mean arterial pressure	CACNA1D SZT2 LRRC10B HECTD4 HDAC7 FERD3L GML GNAS	5.08e-04	499	108	8	EFO_0006340
Disease	alopecia areata (is_marker_for)	HDAC7 KDM4A	5.86e-04	10	108	2	DOID:986 (is_marker_for)
Disease	alcohol use disorder (implicated_via_orthology)	PBRM1 MAP4K1 CIZ1 CDC5L NOTCH3	7.70e-04	195	108	5	DOID:1574 (implicated_via_orthology)
Disease	developmental disorder of mental health (implicated_via_orthology)	NCOR1 NCOR2 GIGYF2	7.77e-04	49	108	3	DOID:0060037 (implicated_via_orthology)
Disease	Calcium channel blocker use measurement	CACNA1C CACNA1D LRRC10B GML GNAS	1.14e-03	213	108	5	EFO_0009930
Disease	Impaired cognition	CACNA1C NOTCH3	1.17e-03	14	108	2	C0338656
Disease	Papillary Renal Cell Carcinoma	LRRK2 SPTBN4 PBRM1 AKAP13	1.28e-03	128	108	4	C1306837
Disease	Renal Cell Carcinoma	LRRK2 SPTBN4 PBRM1 AKAP13	1.28e-03	128	108	4	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	LRRK2 SPTBN4 PBRM1 AKAP13	1.28e-03	128	108	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	LRRK2 SPTBN4 PBRM1 AKAP13	1.28e-03	128	108	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	LRRK2 SPTBN4 PBRM1 AKAP13	1.28e-03	128	108	4	C1266044
Disease	diffuse idiopathic skeletal hyperostosis	NFIL3 CDC5L	1.35e-03	15	108	2	EFO_0007236
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	LRRK2 SPTBN4 PBRM1 AKAP13	2.17e-03	148	108	4	C0279702
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	PBRM1 HSP90AB1	2.18e-03	19	108	2	DOID:4928 (is_marker_for)
Disease	Deaf Mutism	CACNA1D OTOF	2.42e-03	20	108	2	C4082305
Disease	cerebellum white matter volume change measurement, age at assessment	TJP2 SYVN1	2.42e-03	20	108	2	EFO_0008007, EFO_0021498
Disease	Deafness, Acquired	CACNA1D OTOF	2.42e-03	20	108	2	C0751068
Disease	Hearing Loss, Extreme	CACNA1D OTOF	2.42e-03	20	108	2	C0086395
Disease	Complete Hearing Loss	CACNA1D OTOF	2.42e-03	20	108	2	C0581883
Disease	Prelingual Deafness	CACNA1D OTOF	2.42e-03	20	108	2	C0011052
Disease	Bilateral Deafness	CACNA1D OTOF	2.42e-03	20	108	2	C3665473
Disease	renal system measurement, blood urea nitrogen measurement	HECTD4 GNAS	2.92e-03	22	108	2	EFO_0004741, EFO_0004742
Disease	Parkinson disease	LRRK2 GIGYF2	2.92e-03	22	108	2	cv:C0030567
Disease	Myopia	LRP12 FER1L4 CCSER2 TJP2 AKAP13 GNAS	2.97e-03	385	108	6	HP_0000545
Disease	Nonsyndromic Deafness	BDP1 MYO7A TJP2	3.31e-03	81	108	3	C3711374
Disease	sensory perception of sweet taste	CACNA1C AKAP13 KDM4A	3.42e-03	82	108	3	GO_0050916
Disease	Intrahepatic Cholangiocarcinoma	PBRM1 GNAS	3.48e-03	24	108	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	PBRM1 GNAS	3.48e-03	24	108	2	C3805278

Protein segments in the cluster

Peptide	Gene	Start	Entry
EENGPEEVKPVDEME	BDP1	1156	A6H8Y1
MENPEEAIYDDVPRE	ARHGEF10	231	O15013
PDDMDVDEDEDPFGA	DNAJB5	126	O75953
PARPDPIDMDEDELE	CDC5L	136	Q99459
GTEEELPRLFAEEME	CHD5	6	Q8TDI0
SEAPPREPMEAEEVE	BAG6	226	P46379
REPMEAEEVEERAPA	BAG6	231	P46379
PEEPEGEEEDIQMER	ABCA9	1251	Q8IUA7
EPADPGDVEEEEMDS	AKAP13	1526	Q12802
KMPEEEDEAPVLDVR	RCOR1	466	Q9UKL0
EMDSDSGPEAEEPIE	RBSN	721	Q9H1K0
MRPLDIDEVEAPEEV	MRFAP1L1	1	Q96HT8
PADLAEMAREPAEEA	CT47A1	201	Q5JQC4
SEEAAFPPVVEDEEM	NCOR2	691	Q9Y618
DEIPPLEGDEDASRM	HSP90AB1	706	P08238
MEEEEEEEQDPGKPA	IL17RA	811	Q96F46
IEEMGEEDSEVIEPP	PBRM1	1326	Q86U86
GREDDDDVEMLIPIS	LRP12	766	Q9Y561
EEEGPRMFPDLESEF	MAGEA2	91	P43356
APPREEMVDEVCEDE	GPR179	636	Q6PRD1
PSSEPMEEEEDDDLE	L3MBTL2	11	Q969R5
IPPLEGDEDASRMEE	HSP90AB3P	581	Q58FF7
RGHEDPPEEEGEMEE	FER1L4	1036	A9Z1Z3
PEPEDEEEEREHEVM	HERC1	1366	Q15751
EEDPAEEDCPELVPM	CBWD2	11	Q8IUF1
SVELDDELLDPDMDP	CLCN7	61	P51798
DFESPEDMEIDPGEL	MCF2L2	771	Q86YR7
FLESEDEEDEPGMQP	FBXW8	246	Q8N3Y1
AAFNEDEDSEPEEMP	PCNP	111	Q8WW12
DDVEEYMIERPEPEF	PDCD10	86	Q9BUL8
EEQMPREGDSFEVLP	OPTC	31	Q9UBM4
EPMELESYTREPRDD	NFIL3	221	Q16649
PEEEDEDEVSMKGRP	FKBP15	1186	Q5T1M5
GALEPMPTEEDEADD	NOTCH3	1801	Q9UM47
EPEPMEVEEGELEIV	NCBP3	36	Q53F19
REEVMEPPLEEESLE	NES	1116	P48681
PRAGNEEECPEEDME	KDM4A	361	O75164
FIVPGMPEESREDTE	LRRK2	511	Q5S007
EGAVERMAERDEPTP	LRRC10B	231	A6NIK2
MDSQRPEPREEEEEE	ANKRD65	1	E5RJM6
MRPVDADEAREPREE	nan	1	B2RBV5
LFPDERMLEEKEEPG	HECTD4	606	Q9Y4D8
PDEEEDKTMLAERIP	MFSD6	626	Q6ZSS7
PSIEVGPEDMEEARE	PLA2G4F	731	Q68DD2
DDATPVRDEPMDAES	RBBP6	981	Q7Z6E9
DDDLMLDVDLPEDAP	CCSER2	551	Q9H7U1
ETTGEEDEEEPEMPV	CACNA1C	841	Q13936
PIPEEQEMDFRPVDE	GIGYF2	316	Q6Y7W6
IDIEDLEELDPDFIM	EIF3A	656	Q14152
PRRMARFEEGDPEEE	FERD3L	51	Q96RJ6
EMEGDPPADYDDRII	EXTL3	366	O43909
PDIRLEEGAMEDEEL	FOXN3	46	O00409
SMRDDVPPLDREVGE	CLCN5	41	P51795
LEEIEEFLEENMEPG	KLF15	141	Q9UIH9
EDRPSEQLVEEEEPM	HDAC7	936	Q8WUI4
LEPPAPGMEDEEELE	HPS6	356	Q86YV9
EEDPEEEHELPVDME	PPP1R7	56	Q15435
MERRASETPEDGDPE	SBK3	1	P0C264
PRPMDELVTLEEADG	CALCOCO1	121	Q9P1Z2
DMLPDEVTEEELPEG	GML	121	Q99445
EPDPGRDEEDLADEM	CACNA1D	2141	Q01668
MEEPPVREEEEEEGE	RILPL2	1	Q969X0
DEMRADAEAVLAPPE	IRGQ	606	Q8WZA9
GTAEEPEEEEPDESM	OTOF	1311	Q9HC10
PLAGPEDFSEEEMER	HGH1	251	Q9BTY7
EDFSEEEMERLPVDL	HGH1	256	Q9BTY7
MDVVDPDIFNRDPRD	MAP4K1	1	Q92918
EMPEDGEPDAAELRR	SYVN1	591	Q86TM6
MASERPEPEVEEAGQ	SZT2	1	Q5T011
EAIELPEPEAMELER	UTP20	1706	O75691
PEPEAMELERVDEEE	UTP20	1711	O75691
PPEDDDMNEDTVERI	RELL2	61	Q8NC24
EEELFPESERPEMLS	PUF60	421	Q9UHX1
REEEEEEEEEMVPAP	TMEM132A	826	Q24JP5
RPPVEEEAAEMEGAA	GNAS	351	Q5JWF2
EEDADPEFPELRMDS	PRR23B	156	Q6ZRT6
DEDVDGEPERQRMFP	NCOR1	886	O75376
EEEEEKDREIPVPLM	FGD1	346	P98174
LEGETFPLERDEVMP	STRIP1	391	Q5VSL9
EMIEDEEGLVDDRAP	SHPRH	1271	Q149N8
DDPPAQIREEEDEMG	PI4KB	91	Q9UBF8
EPELEAEMPAQEDDL	ARHGAP4	731	P98171
DKVEEMEPLEPGRDE	SLX4	901	Q8IY92
AEPVEDEAERSALPM	STK32C	461	Q86UX6
TDEEPAEPEDMERFE	CCDC136	836	Q96JN2
DLRAAENLDEPFPEM	ANGEL1	116	Q9UNK9
PEEYMEPEGADPREA	NCAPH2	441	Q6IBW4
MPEDLAEADDEGEPE	CNGA4	541	Q8IV77
EVEPEPEMEAEVEPE	CNGB1	26	Q14028
EEAAEPRMDTPEDQD	CIZ1	216	Q9ULV3
PPLDQDDRAFEVMDE	TJP2	131	Q9UDY2
EEMFPDEVDTPRDVA	TSR1	481	Q2NL82
DVEMAEIPASVRDDP	ZSCAN5DP	141	P0CG00
KEQEEEEEGLPPMDL	ZFHX2	96	Q9C0A1
IVEPMEQFDDEDGLP	PSPC1	231	Q8WXF1
HLRAPAEPMAEEEEE	PLPPR3	431	Q6T4P5
TAMDDLDEDEEPAPA	RNF123	636	Q5XPI4
DEMELEETEPPLEPE	P3H4	381	Q92791
MVEEGEPDPEFEAIL	SPTAN1	2361	Q13813
DVPDDAMEIPIGDRL	SUSD1	661	Q6UWL2
DLMEGEAEFEDEPPP	SUGP2	866	Q8IX01
REAELESPEVMPEEE	SUGP2	881	Q8IX01
EKEFQPLDVMEPEDD	WDFY4	1126	Q6ZS81
EEMEEEAIASLPGEE	CREBZF	81	Q9NS37
RLLDPEDVNMEAPDE	SPTBN4	256	Q9H254
VRGLMEEDAEPIFED	STAG1	1186	Q8WVM7
DDDEEPEFSSAMPLE	SF3B3	366	Q15393
DSEDREGDPEEREMG	ZNF697	26	Q5TEC3
PLEPEEEEEVELELM	ZNF853	311	P0CG23
EEEEVELELMPVDLG	ZNF853	316	P0CG23
EEDPDSMEAPTRIRD	WDR55	16	Q9H6Y2
DARVRPEEEEEPLME	PIGO	981	Q8TEQ8
PEEEEEEMDVREKGP	PRR29	91	P0C7W0
EEEEEGLEMDERGPS	PLEKHG2	596	Q9H7P9
EEMPAGEIEQFEEAP	TASOR2	1296	Q5VWN6
AFQLPESEMPEEGDE	TSNAXIP1	611	Q2TAA8
PFADEEEEEEMLLRE	ZFC3H1	616	O60293
GMRPEESDSELLEDE	PPIP5K1	31	Q6PFW1
PEEREIPMDPEAGAE	ZNF282	266	Q9UDV7
RMPTKEDEEEDEPVV	TPX2	496	Q9ULW0
EEDDDGIPPDSLERM	ZBED4	26	O75132
KPEEEEAMDEDRPAE	VSX2	336	P58304
EMVEEDLDAALPLPD	MYO7A	976	Q13402
PMAEEPEEDVDGLAE	MYO7B	956	Q6PIF6