Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FRAS1 VWF LAMA1 ZP2 SSPOP FBLN2 FBN1 MUC2 FBN3

1.93e-051881589GO:0005201
GeneOntologyMolecularFunctionubiquitin conjugating enzyme binding

SIAH2 RNF217 PRKN RNF180

1.82e-04361584GO:0031624
GeneOntologyCellularComponentextracellular matrix

FBLN7 INHBE FRAS1 VWF LAMA1 MUC5B ADAMTS5 SMOC2 ZP2 SSPOP F12 SVEP1 TGM4 FBLN2 FBN1 GPC3 FCN2 CD180 MUC2 FBN3

1.69e-0765616120GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

FBLN7 INHBE FRAS1 VWF LAMA1 MUC5B ADAMTS5 SMOC2 ZP2 SSPOP F12 SVEP1 TGM4 FBLN2 FBN1 GPC3 FCN2 CD180 MUC2 FBN3

1.77e-0765816120GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

INHBE FRAS1 VWF LAMA1 ADAMTS5 SMOC2 ZP2 SSPOP F12 TGM4 FBLN2 FBN1 GPC3 FCN2 MUC2

1.56e-0553016115GO:0062023
DomainVWC_out

FRAS1 VWF CRIM1 KCP MUC5B SSPOP JAG2 MUC2

1.61e-12191598SM00215
DomainVWFC_1

FRAS1 VWF CRIM1 KCP MUC5B SSPOP JAG2 PXDNL MUC2

1.45e-11361599PS01208
DomainVWFC_2

FRAS1 VWF CRIM1 KCP MUC5B SSPOP JAG2 PXDNL MUC2

2.47e-11381599PS50184
DomainVWC

FRAS1 VWF CRIM1 KCP MUC5B SSPOP JAG2 PXDNL MUC2

2.47e-11381599SM00214
DomainVWF_dom

FRAS1 VWF CRIM1 KCP MUC5B SSPOP JAG2 PXDNL MUC2

6.56e-11421599IPR001007
DomainGrowth_fac_rcpt_

FRAS1 CRIM1 KRT32 LAMA1 MUC13 SVEP1 JAG2 FBLN2 FBN1 MEGF8 FBN3 NOTCH4 EPHA7

8.21e-1015615913IPR009030
DomainEGF_2

FBLN7 LAMA1 MUC13 SSPOP F12 SVEP1 JAG2 FBLN2 FBN1 MALRD1 MEGF8 ASTN2 FBN3 NOTCH4 EPHA7

8.40e-0926515915PS01186
DomainEGF_1

FBLN7 LAMA1 MUC13 SSPOP F12 SVEP1 JAG2 FBLN2 FBN1 MALRD1 MEGF8 ASTN2 FBN3 NOTCH4

3.96e-0825515914PS00022
DomainUnchr_dom_Cys-rich

VWF KCP MUC5B SSPOP MUC2

5.11e-08131595IPR014853
DomainC8

VWF KCP MUC5B SSPOP MUC2

5.11e-08131595SM00832
DomainTIL_dom

VWF KCP MUC5B SSPOP MUC2

7.90e-08141595IPR002919
DomainVWC

FRAS1 VWF CRIM1 KCP MUC5B PXDNL

1.12e-07281596PF00093
DomainEGF

FBLN7 FRAS1 LAMA1 MUC13 F12 SVEP1 JAG2 FBLN2 FBN1 MALRD1 MEGF8 FBN3 NOTCH4

1.13e-0723515913SM00181
DomainEGF_3

FBLN7 MUC13 SSPOP F12 SVEP1 JAG2 FBLN2 FBN1 MALRD1 MEGF8 ASTN2 FBN3 NOTCH4

1.13e-0723515913PS50026
DomainVWF_type-D

VWF KCP MUC5B SSPOP MUC2

1.70e-07161595IPR001846
DomainVWFD

VWF KCP MUC5B SSPOP MUC2

1.70e-07161595PS51233
DomainVWD

VWF KCP MUC5B SSPOP MUC2

1.70e-07161595SM00216
DomainVWD

VWF KCP MUC5B SSPOP MUC2

1.70e-07161595PF00094
DomainEGF-like_dom

FBLN7 FRAS1 LAMA1 MUC13 F12 SVEP1 JAG2 FBLN2 FBN1 MALRD1 MEGF8 FBN3 NOTCH4

2.21e-0724915913IPR000742
DomainEGF-like_CS

FBLN7 LAMA1 MUC13 F12 SVEP1 JAG2 FBLN2 FBN1 MALRD1 MEGF8 FBN3 NOTCH4 EPHA7

3.79e-0726115913IPR013032
DomainEGF_CA

FBLN7 SVEP1 JAG2 FBLN2 FBN1 MEGF8 FBN3 NOTCH4

6.99e-07861598PF07645
DomainEGF_CA

FBLN7 F12 SVEP1 JAG2 FBLN2 FBN1 MEGF8 FBN3 NOTCH4

1.00e-061221599SM00179
DomainEGF-like_Ca-bd_dom

FBLN7 F12 SVEP1 JAG2 FBLN2 FBN1 MEGF8 FBN3 NOTCH4

1.15e-061241599IPR001881
DomainEGF_Ca-bd_CS

FBLN7 SVEP1 JAG2 FBLN2 FBN1 MEGF8 FBN3 NOTCH4

1.76e-06971598IPR018097
DomainEGF_CA

FBLN7 SVEP1 JAG2 FBLN2 FBN1 MEGF8 FBN3 NOTCH4

2.05e-06991598PS01187
DomainASX_HYDROXYL

FBLN7 SVEP1 JAG2 FBLN2 FBN1 MEGF8 FBN3 NOTCH4

2.22e-061001598PS00010
DomainC8

VWF MUC5B SSPOP MUC2

2.37e-06121594PF08742
DomainTIL

VWF MUC5B SSPOP MUC2

2.37e-06121594PF01826
DomainEGF-type_Asp/Asn_hydroxyl_site

FBLN7 SVEP1 JAG2 FBLN2 FBN1 MEGF8 FBN3 NOTCH4

3.44e-061061598IPR000152
DomainCTCK_1

VWF MUC5B SSPOP MUC2

1.41e-05181594PS01185
DomainLDLR_class-A_CS

TMPRSS15 CD320 MFRP SSPOP MALRD1

2.17e-05401595IPR023415
DomainLdl_recept_a

TMPRSS15 CD320 MFRP SSPOP MALRD1

3.90e-05451595PF00057
Domain-

TMPRSS15 CD320 MFRP SSPOP MALRD1

4.34e-054615954.10.400.10
DomainLDLRA_1

TMPRSS15 CD320 MFRP SSPOP MALRD1

5.35e-05481595PS01209
DomainCys_knot_C

VWF MUC5B SSPOP MUC2

5.56e-05251594IPR006207
DomainCTCK_2

VWF MUC5B SSPOP MUC2

5.56e-05251594PS01225
DomainLDrepeatLR_classA_rpt

TMPRSS15 CD320 MFRP SSPOP MALRD1

5.92e-05491595IPR002172
DomainLDLa

TMPRSS15 CD320 MFRP SSPOP MALRD1

5.92e-05491595SM00192
DomainLDLRA_2

TMPRSS15 CD320 MFRP SSPOP MALRD1

5.92e-05491595PS50068
DomainhEGF

SVEP1 JAG2 FBN3 NOTCH4

8.83e-05281594PF12661
DomainEphrin_rec_like

SVEP1 TG EPHA7

9.50e-05111593PF07699
DomainEGF

FBLN7 F12 SVEP1 JAG2 MALRD1 FBN3 NOTCH4

1.03e-041261597PF00008
DomainIBR

RNF217 FBXO43 PRKN

2.06e-04141593PF01485
DomainIBR

RNF217 FBXO43 PRKN

2.06e-04141593SM00647
DomainFBN

FBN1 FBN3

2.15e-0431592IPR011398
DomainIBR_dom

RNF217 FBXO43 PRKN

2.56e-04151593IPR002867
DomainCT

VWF MUC5B MUC2

8.28e-04221593SM00041
DomainWxxW_domain

MUC5B MUC2

1.06e-0361592IPR025155
DomainMucin2_WxxW

MUC5B MUC2

1.06e-0361592PF13330
DomainEphrin_rec_like

SVEP1 TG EPHA7

1.21e-03251593SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SVEP1 TG EPHA7

1.21e-03251593IPR011641
DomaincEGF

FBLN2 FBN1 FBN3

1.36e-03261593PF12662
DomaincEGF

FBLN2 FBN1 FBN3

1.36e-03261593IPR026823
DomainTB

FBN1 FBN3

1.47e-0371592PF00683
DomainNotch_dom

PAPPA2 NOTCH4

1.47e-0371592IPR000800
DomainNotch

PAPPA2 NOTCH4

1.47e-0371592PF00066
DomainNL

PAPPA2 NOTCH4

1.47e-0371592SM00004
DomainDWB

SMAD1 SMAD9

1.95e-0381592SM00524
DomainMH2

SMAD1 SMAD9

1.95e-0381592PS51076
DomainMH1

SMAD1 SMAD9

1.95e-0381592PS51075
Domain-

FBN1 FBN3

1.95e-03815923.90.290.10
Domain-

SMAD1 SMAD9

1.95e-03815923.90.520.10
DomainMAD_homology_MH1

SMAD1 SMAD9

1.95e-0381592IPR013019
DomainDwarfin

SMAD1 SMAD9

1.95e-0381592IPR013790
DomainEPL1

BRPF1 BRD1

1.95e-0381592PF10513
DomainEnhancer_polycomb-like_N

BRPF1 BRD1

1.95e-0381592IPR019542
DomainMH2

SMAD1 SMAD9

1.95e-0381592PF03166
DomainSMAD_dom_Dwarfin-type

SMAD1 SMAD9

1.95e-0381592IPR001132
DomainTSP_1

ADGRB2 ADAMTS5 THSD7B SSPOP

2.04e-03631594PF00090
DomainTSP1

ADGRB2 ADAMTS5 THSD7B SSPOP

2.29e-03651594SM00209
DomainTSP1_rpt

ADGRB2 ADAMTS5 THSD7B SSPOP

2.29e-03651594IPR000884
DomainTSP1

ADGRB2 ADAMTS5 THSD7B SSPOP

2.29e-03651594PS50092
DomainAlpha_adaptinC2

GGA2 AP1B1

2.49e-0391592PF02883
DomainTB_dom

FBN1 FBN3

2.49e-0391592IPR017878
DomainClathrin_a/b/g-adaptin_app_Ig

GGA2 AP1B1

2.49e-0391592IPR008152
DomainAlpha_adaptinC2

GGA2 AP1B1

2.49e-0391592SM00809
DomainTB

FBN1 FBN3

2.49e-0391592PS51364
DomainE3_UB_ligase_RBR

RNF217 PRKN

3.10e-03101592IPR031127
PathwayWP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM

SPRY1 FRAS1 CRIM1 ITGA8 GPC3 SMAD1

7.76e-06601126M40048
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC5B ADAMTS5 THSD7B MUC13 SSPOP NOTCH4

1.61e-05681126M27303
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 TBKBP1 MAEA ADGRB2 SIAH2 HUWE1 PRAG1 BABAM2 ADCY9 TYK2 JAG2 KANSL1 EPOP MEGF8 PLEKHM2 CDK13 MTMR3 DIP2C NLRC5 IRS2 SNX11

7.25e-0811051652135748872
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

SPRY1 VWF CRIM1 TSPOAP1 ITPRID2 JAG2 FBN1 MEGF8

1.02e-07118165821078624
Pubmed

Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon.

SMAD1 PLCE1 SMAD9

1.04e-065165315743817
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC5B TFF2 JAG2 MUC2 NOTCH4

1.48e-0641165522675208
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TBKBP1 EPB41L4B MAEA ENC1 HUWE1 KLKP1 SMOC2 SSPOP BABAM2 ITFG1 TYK2 JAG2 ATXN1 CDK13 HPN LRRC1 DIP2C NLRC5 ASTN2 PRKN HSD11B2 CPNE7

2.40e-0614891652228611215
Pubmed

Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.

SMOC2 JAG2 MUC2 SMAD1 SMAD9

2.95e-0647165532747435
Pubmed

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.

FRAS1 ITGA8 SMAD1 SMAD9

4.03e-0623165418787044
Pubmed

Functional proteomics mapping of a human signaling pathway.

PAPPA2 VWF SIAH2 HUWE1 SVEP1 MTMR11 KANSL1 AP1B1 CDK13 BRD1 SMAD1 VCPIP1 SMAD9

5.46e-065911651315231748
Pubmed

Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

LAMA1 FBN1 SMAD1 NOTCH4

7.87e-0627165435894043
Pubmed

Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.

SRY JAG2 NOTCH4

8.63e-069165311944948
Pubmed

Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program.

VWF SMOC2 SMAD1 SMAD9

1.58e-0532165430936179
Pubmed

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.

JAG2 SMAD1 NOTCH4 SMAD9

2.03e-0534165421311046
Pubmed

Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.

CRIM1 SMAD1 SMAD9

2.24e-0512165317460146
Pubmed

Confocal laser scanning analysis of the association of fibulin-2 with fibrillin-1 and fibronectin define different stages of skin regeneration.

FBLN2 FBN1

2.24e-05216529886271
Pubmed

Fibrillin-1 and alpha8 integrin are co-expressed in the glomerulus and interact to convey adhesion of mesangial cells.

ITGA8 FBN1

2.24e-052165225482639
Pubmed

Fibrillin-1 and fibulin-2 interact and are colocalized in some tissues.

FBLN2 FBN1

2.24e-05216528702639
Pubmed

Regulation of human MutYH DNA glycosylase by the E3 ubiquitin ligase mule.

HUWE1 MUTYH

2.24e-052165224443563
Pubmed

Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain.

BRPF1 BRD1

2.24e-052165224333487
Pubmed

The complete cDNA sequence and structural polymorphism of the polypeptide chain of porcine submaxillary mucin.

VWF MUC2

2.24e-05216529407109
Pubmed

Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.

FBN1 FBN3

2.24e-052165215221638
Pubmed

TALEN-mediated editing of the mouse Y chromosome.

SRY UTY

2.24e-052165223666012
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC5B MUC2

2.24e-052165220873538
Pubmed

RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family.

MUC13 CD180

2.24e-05216527897216
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 TSPOAP1 FHIP2A SNX19 KANSL1 MEGF8 PLEKHM2 MTMR3 PLCE1 VCPIP1

2.70e-054071651012693553
Pubmed

Regional regulation of Filiform tongue papillae development by Ikkα/Irf6.

JAG2 SMAD1 SMAD9

2.90e-0513165327302476
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

LAMA1 TG SMAD1 SMAD9

3.91e-0540165427068110
Pubmed

Sprouty1 haploinsufficiency prevents renal agenesis in a model of Fraser syndrome.

SPRY1 FRAS1 ITGA8

4.58e-0515165323064016
Pubmed

The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation.

LAMA1 SMAD1 SMAD9

5.61e-0516165319733164
Pubmed

Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx5.

MUC13 TFF2 SMAD1 SMAD9

5.72e-0544165429463648
Pubmed

Non-canonical cyclic AMP SMAD1/5/8 signalling in human granulosa cells.

SMAD1 SMAD9

6.69e-053165230953749
Pubmed

The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2.

TYK2 IRS2

6.69e-05316528550573
Pubmed

Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys.

SMAD1 SMAD9

6.69e-053165221381028
Pubmed

Smad1 and 5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis toward the postnatal state.

SMAD1 SMAD9

6.69e-053165224023003
Pubmed

Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice.

SMAD1 SMAD9

6.69e-053165231127639
Pubmed

Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils.

VWF F12

6.69e-053165230898865
Pubmed

Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences.

LAMA1 FBLN2

6.69e-05316529006922
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC2

6.69e-053165219718741
Pubmed

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells.

ADAMTS5 FBLN2

6.69e-053165228099917
Pubmed

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1.

BRPF1 BRD1

6.69e-053165220400950
Pubmed

MADR1, a MAD-related protein that functions in BMP2 signaling pathways.

SMAD1 SMAD9

6.69e-05316528653785
Pubmed

Autosomal recessive polycystic kidney disease epithelial cell model reveals multiple basolateral epidermal growth factor receptor sorting pathways.

AP1B1 BICC1

6.69e-053165220519437
Pubmed

Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation.

SMAD1 SMAD9

6.69e-053165227848974
Pubmed

Structural and functional analysis of the recombinant G domain of the laminin alpha4 chain and its proteolytic processing in tissues.

LAMA1 FBLN2

6.69e-053165210934193
Pubmed

Activated NF-κB in bone marrow mesenchymal stem cells from systemic lupus erythematosus patients inhibits osteogenic differentiation through downregulating Smad signaling.

SMAD1 SMAD9

6.69e-053165222897816
Pubmed

The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1.

SACS ATXN1

6.69e-053165219208651
Pubmed

Siah proteins induce the epidermal growth factor-dependent degradation of phospholipase Cepsilon.

SIAH2 PLCE1

6.69e-053165217998205
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC5B MUC13 MUC2

8.12e-0518165318834073
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

FBN1 SMAD1 SMAD9

8.12e-0518165335503090
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

INHBE VWF F12 FBLN2 FBN1 MUC2

9.45e-05153165625037231
Pubmed

LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea.

JAG2 SMAD1 SMAD9

9.61e-0519165325057208
Pubmed

BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter.

FBLN2 SMAD1 SMAD9

1.13e-0420165328655168
Pubmed

ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.

ADAMTS5 SMAD1 SMAD9

1.13e-0420165319922873
Pubmed

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

VWF SIAH2 SNX19 TG TYK2

1.13e-0499165519730683
Pubmed

Ureteric morphogenesis requires Fgfr1 and Fgfr2/Frs2α signaling in the metanephric mesenchyme.

SPRY1 SMAD1 SMAD9

1.31e-0421165322282599
Pubmed

Mendelian randomization and experimental IUGR reveal the adverse effect of low birth weight on lung structure and function.

VWF SMAD1 SMAD9

1.31e-0421165333372189
Pubmed

A crucial role of a high mobility group protein HMGA2 in cardiogenesis.

SMAD1 SMAD9

1.33e-044165218425117
Pubmed

Bone morphogenetic protein 4 promotes mammalian oogonial stem cell differentiation via Smad1/5/8 signaling.

SMAD1 SMAD9

1.33e-044165223993924
Pubmed

Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.

BRPF1 BRD1

1.33e-044165224258712
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN3

1.33e-044165225034023
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC2

1.33e-044165225638393
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC2

1.33e-044165222269464
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

JAG2 MUC2

1.33e-044165222691042
Pubmed

A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.

FRAS1 DIP2C

1.33e-044165223703922
Pubmed

Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin.

SMAD1 SMAD9

1.33e-044165222452883
Pubmed

Accumulation of gene polymorphisms related to plaque disruption and thrombosis is associated with cerebral infarction in subjects with type 2 diabetes.

VWF F12

1.33e-044165219933990
Pubmed

SIAH2 antagonizes TYK2-STAT3 signaling in lung carcinoma cells.

SIAH2 TYK2

1.33e-044165224833526
Pubmed

Characterization of new bone morphogenetic protein (Bmp)-2 regulatory alleles.

SMAD1 SMAD9

1.33e-044165228401685
Pubmed

Regulation of Sprouty2 stability by mammalian Seven-in-Absentia homolog 2.

SPRY1 SIAH2

1.33e-044165216888801
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC2

1.33e-044165223807779
Pubmed

Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering.

FBLN2 FBN1

1.33e-044165215610515
Pubmed

Downregulation of Grem1 expression in the distal limb mesoderm is a necessary precondition for phalanx development.

SMAD1 SMAD9

1.33e-044165234719843
Pubmed

The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival.

BRPF1 BRD1

1.33e-044165226677226
Pubmed

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.

BRPF1 BRD1

1.33e-044165224065767
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC2

1.33e-044165217471237
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC2

1.33e-044165214984930
Pubmed

Lack of evidence that fibrillin1 regulates bone morphogenetic protein 4 activity in kidney or lung.

FBN1 SMAD1

1.33e-044165236825302
Pubmed

Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.

SMAD1 SMAD9

1.33e-044165217967875
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC2

1.33e-044165229869461
Pubmed

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

MUC5B MUC2

1.33e-044165221596555
Pubmed

A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses.

CHST2 FUT7

1.33e-044165237735247
Pubmed

KMUP-1 Promotes Osteoblast Differentiation Through cAMP and cGMP Pathways and Signaling of BMP-2/Smad1/5/8 and Wnt/β-Catenin.

SMAD1 SMAD9

1.33e-044165225536014
Pubmed

Serotonin induces Rho/ROCK-dependent activation of Smads 1/5/8 in pulmonary artery smooth muscle cells.

SMAD1 SMAD9

1.33e-044165219244313
Pubmed

A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.

NRDC THSD7B

1.33e-044165221703634
Pubmed

Signal transduction of bone morphogenetic protein receptors.

SMAD1 SMAD9

1.33e-044165214687659
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC2

1.33e-044165212676567
Pubmed

Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell Differentiation.

SMAD1 SMAD9

1.33e-044165225755279
Pubmed

FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development.

SPRY1 FBLN2 SMAD1 SMAD9

1.38e-0455165435020897
Pubmed

The role of Irf6 in tooth epithelial invagination.

JAG2 SMAD1 SMAD9

1.51e-0422165322366192
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FRAS1 VWF LAMA1 FBLN2 FBN1 MUC2

1.53e-04167165622159717
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZNF469 CDK13 ZNF333 FBN3 VCPIP1

1.63e-04107165511347906
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

SIAH2 SSPOP BABAM2 JAG2 FBLN2 ZBTB32 MEGF8 SACS ATXN1 USP54 RTL8C

1.66e-046081651116713569
Pubmed

Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion.

JAG2 SMAD1 SMAD9

1.73e-0423165329981310
Pubmed

Msx genes define a population of mural cell precursors required for head blood vessel maturation.

VWF SMAD1 SMAD9

1.73e-0423165321693521
Pubmed

Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.

GGA2 ITPRID2 RIN1 IRS2 BICC1

1.85e-04110165537219487
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

VWF LAMA1 ADAMTS5 MFRP SVEP1 FBLN2 FBN1

1.92e-04248165724006456
Pubmed

Betulinic acid synergically enhances BMP2-induced bone formation via stimulating Smad 1/5/8 and p38 pathways.

SMAD1 SMAD9

2.22e-045165227188281
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC2

2.22e-045165211062147
Pubmed

A Japanese-specific allele in the GALNT11 gene.

FBN1 CEP152

2.22e-045165220547088
Pubmed

Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells.

SMAD1 SMAD9

2.22e-045165211121043
Pubmed

Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14.

MUC13 MUC2

2.22e-045165212507512
InteractionATXN7 interactions

SPRY1 VWF CRIM1 ITPRID2 JAG2 FBN1 MEGF8 PRKN

2.43e-061091598int:ATXN7
Cytoband2p23.2

PCARE BABAM2 SPDYA

1.25e-051316432p23.2
GeneFamilyCD molecules|Mucins

MUC5B MUC13 MUC2

2.55e-04211083648
GeneFamilySMAD family

SMAD1 SMAD9

9.67e-0481082750
GeneFamilyFibulins

FBLN7 FBLN2

9.67e-0481082556
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR11 MTMR3

3.53e-03151082903
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF134 ZNF786 ZNF490 ZNF469 ZBTB32 ZNF665 ZNF648 ZNF333 ZBTB18 ZNF564 ZNF646

3.75e-037181081128
GeneFamilyExonucleases

TREX1 AEN

4.02e-03161082544
GeneFamilyOTU domain containing

OTUD7A VCPIP1

4.53e-03171082669
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAPPA2 FBLN7 SVEP1

4.80e-035710831179
GeneFamilyLIM domain containing

PDLIM3 WTIP FHL3

5.29e-035910831218
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLA2G4E PLCE1

5.66e-03191082832
GeneFamilyProteases, serine

TMPRSS15 PRSS36 HPN

6.35e-03631083738
CoexpressionNABA_ECM_GLYCOPROTEINS

FBLN7 FRAS1 VWF CRIM1 LAMA1 KCP SMOC2 ZP2 SSPOP SVEP1 FBLN2 FBN1 PXDNL FBN3

2.44e-1119616314M3008
CoexpressionNABA_MATRISOME

PAPPA2 FBLN7 INHBE FRAS1 TMPRSS15 VWF CRIM1 LAMA1 KCP MUC5B ADAMTS5 MUC13 SMOC2 ZP2 SSPOP F12 SVEP1 TGM4 FBLN2 FBN1 GPC3 MEGF8 PXDNL FCN2 MUC2 FBN3

1.11e-09102616326M5889
CoexpressionNABA_CORE_MATRISOME

FBLN7 FRAS1 VWF CRIM1 LAMA1 KCP SMOC2 ZP2 SSPOP SVEP1 FBLN2 FBN1 PXDNL FBN3

2.11e-0927516314M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

FBLN7 FRAS1 VWF CRIM1 LAMA1 KCP SMOC2 ZP2 SSPOP SVEP1 FBLN2 FBN1

2.95e-0919116312MM17059
CoexpressionNABA_MATRISOME

PAPPA2 FBLN7 INHBE FRAS1 TMPRSS15 VWF CRIM1 LAMA1 KCP MUC5B ADAMTS5 MUC13 SMOC2 MFRP ZP2 SSPOP F12 SVEP1 TGM4 FBLN2 FBN1 GPC3 MEGF8 FCN2 MUC2

3.73e-09100816325MM17056
CoexpressionNABA_CORE_MATRISOME

FBLN7 FRAS1 VWF CRIM1 LAMA1 KCP SMOC2 ZP2 SSPOP SVEP1 FBLN2 FBN1

1.37e-0727016312MM17057
CoexpressionDESCARTES_FETAL_PANCREAS_VASCULAR_ENDOTHELIAL_CELLS

CD320 JAG2 SLC9C1 EXOC3L1 NOSTRIN NOTCH4

3.22e-06651636M40266
CoexpressionJONES_OVARY_PERICYTE

SELENOP CRIM1 SNRK ADAMTS5 SMOC2 FBN1 C11orf96 NOSTRIN

1.28e-051721638M48351
CoexpressionJONES_OVARY_NK_CELL

CRIM1 SNRK ADAMTS5 SMOC2 FBN1 NOTCH4

2.00e-05891636M48353
CoexpressionAIZARANI_LIVER_C10_MVECS_1

SPRY1 VWF CRIM1 SNRK CD320 FBLN2 C11orf96 NOSTRIN NOTCH4

4.99e-052691639M39114
CoexpressionBHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP

VWF TBKBP1 SIAH2 MCM10 ADCY9 TFF2 PDLIM3 AP1B1

5.52e-052111638M2230
CoexpressionJONES_OVARY_ENDOTHELIAL

SELENOP VWF CRIM1 SNRK NOSTRIN SMAD1 NOTCH4

7.19e-051621637M48350
CoexpressionCUI_DEVELOPING_HEART_C3_FIBROBLAST_LIKE_CELL

SPRY1 SMOC2 FBLN2 FBN1 GPC3 BICC1

9.34e-051171636M39300
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

PAPPA2 ENC1 LAMA1 ITGA8 ADAMTS5 SMOC2 SVEP1 FBLN2 FBN1 GPC3 HSD11B2 CDC25C UTY BICC1 PLCE1 VCPIP1 EPHA7

5.19e-0576815617gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

LAMA1 ADAMTS5 SMOC2 SVEP1 FBN1 GPC3 PDLIM3 BICC1

6.16e-051821568gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

PAPPA2 ENC1 LAMA1 ITGA8 SMOC2 FBLN2 FBN1 GPC3 HSD11B2 BICC1 EPHA7

8.21e-0536415611gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2

TREX1 TBKBP1 SPNS2 ENC1 ADGRB2 KCP SIAH2 SMOC2 PRSS36 SVEP1 FBLN2 MTMR11 FBN1 GPC3 WTIP PRKN PRR14L RNF180 FHL3 BICC1 PLCE1 SMAD9

9.54e-05122815622facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

PAPPA2 LAMA1 ITGA8 ADAMTS5 SMOC2 SVEP1 FBN1 GPC3 HSD11B2 BICC1

1.02e-0431015610gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

VWF EPB41L4B ENC1 ADGRB2 KCP SMOC2 RNF217 SVEP1 FBLN2 FBN1 GPC3 MEGF8 LRRC1 PRR14L CHST2 CD180 RNF180 BICC1 PLCE1 EPHA7 SMAD9

1.04e-04114815621facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlasJC_iEC_top-relative-expression-ranked_2500_k-means-cluster#1

FBLN7 FAM110D ENC1 ITGA8 SNRK ITPRID2 ADAMTS5 CD320 ADGB MTMR11 SACS EXOC3L1 NOSTRIN RNF180 EPHA7

1.34e-0467215615JC_iEC_2500_K1
ToppCelldroplet-Bladder-Unstain-18m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 VWF TBKBP1 SPNS2 FAM110D ITGA8 C16orf89 C11orf96 NOTCH4 CPNE7

3.05e-0919516410fbfe4a8ae9775764108b45920eec92003b24fb2e
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 VWF TBKBP1 SPNS2 FAM110D ITGA8 C16orf89 C11orf96 NOTCH4 CPNE7

3.05e-09195164102a6056172c41c46acfe0242be22269ef1d07921e
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPRY1 VWF CRIM1 SPNS2 FAM110D JAG2 LRRC1 NOSTRIN NOTCH4 SMAD9

3.89e-092001641027507c4b41d45c7cc50e4993169c0302be22ee34
ToppCellParenchyma_COVID-19-Endothelial-TX-Endothelial-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SPRY1 VWF CRIM1 SPNS2 FAM110D JAG2 LRRC1 NOSTRIN NOTCH4 SMAD9

3.89e-0920016410b65fb8d378abd91cdabf5faac5f4b90d527f8c44
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPRY1 VWF CRIM1 SPNS2 FAM110D JAG2 LRRC1 NOSTRIN NOTCH4 SMAD9

3.89e-09200164102cb6e35add34b9dc564ebcf5d3cbc761325ca9f4
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 SELENOP FRAS1 CRIM1 ITGA8 PCARE SVEP1 GPC3 BICC1

2.06e-0817716498220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 SELENOP FRAS1 CRIM1 ITGA8 PCARE SVEP1 GPC3 BICC1

2.06e-0817716497617270f49cd6b7ba66db72d20560cee985012b2
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM110D ENC1 SNRK ADAMTS5 CRACR2B C16orf89 EXOC3L1 CHST2 NOSTRIN

3.47e-08188164951c6796a9488c056a10d048082015342c2e037f9
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM110D ENC1 SNRK ADAMTS5 CRACR2B C16orf89 EXOC3L1 CHST2 NOSTRIN

3.47e-081881649b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF SPNS2 FAM110D CRACR2B C16orf89 FBLN2 PDLIM3 EXOC3L1 NOTCH4

3.64e-0818916492e43428f1ef9683c6f8c9897d46aa7d34bf9047f
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF SPNS2 FAM110D LAMA1 CRACR2B C16orf89 RIN1 PDLIM3 C11orf96

3.98e-0819116499fc674a58f20b47255e4457d5195c8cff17b0414
ToppCelldroplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF SPNS2 FAM110D LAMA1 CRACR2B C16orf89 RIN1 PDLIM3 C11orf96

3.98e-081911649c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCelldroplet-Fat-Mat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 SPNS2 FAM110D SNRK CRACR2B C16orf89 PDLIM3 C11orf96

4.35e-08193164954024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCelldroplet-Fat-Mat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 SPNS2 FAM110D SNRK CRACR2B C16orf89 PDLIM3 C11orf96

4.35e-08193164981d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 VWF SPNS2 FAM110D ITGA8 C16orf89 C11orf96 NOTCH4 CPNE7

4.55e-0819416499d7cbbcf995274019ca10be0562f114513ec197a
ToppCelldroplet-Fat-Mat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 SPNS2 FAM110D SNRK CRACR2B C16orf89 PDLIM3 C11orf96

4.55e-08194164974d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCelldistal-Endothelial-Bronchial_Vessel_1-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPRY1 VWF CRIM1 FAM110D FBLN2 EPOP FCN2 LRRC1 NOSTRIN

5.19e-0819716490d1afd1ad7489c071db08b3dfff598423097d7e0
ToppCell3'-Parenchyma_lung-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA8 ADAMTS5 SVEP1 FBLN2 FBN1 GPC3 PDLIM3 C11orf96 BICC1

5.91e-082001649ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCellmedial-Endothelial-Vein-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWF CRIM1 SPNS2 FAM110D EPOP LRRC1 LTF NOSTRIN SMAD9

5.91e-0820016493f689029f5bc7db0af50a405f1e252aeec529077
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

SPRY1 SELENOP LAMA1 ITGA8 SVEP1 FBN1 GPC3 PXDNL BICC1

5.91e-082001649a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellmedial-Endothelial-Vein|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWF CRIM1 SPNS2 FAM110D EPOP LRRC1 LTF NOSTRIN SMAD9

5.91e-0820016491163e5f6dfb304c94bf8885629350454f4b6bee8
ToppCellmedial-2-Endothelial-Vein|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWF CRIM1 SPNS2 FAM110D EPOP LRRC1 LTF NOSTRIN SMAD9

5.91e-08200164949da4e3ff10262a492c2cf566a7f2e35e418bfda
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

PLA2G4E ZNF469 FBLN2 FBN1 LTF CD180 FHL3 BICC1

2.13e-071681648aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_RSAD2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HTR2C ITGA8 RFPL4B SLC9C1 LRRC1 HS3ST4 LMNTD1 CPNE7

2.33e-07170164863dfbc4746717132dc81b6bac868c7498fc96283
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRAS1 CRIM1 ADAMTS5 SMOC2 FBLN2 GPC3 BICC1 PLCE1

2.66e-07173164830d67738633493d47f06ae452424382f069b6c0a
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRAS1 CRIM1 ADAMTS5 SMOC2 FBLN2 GPC3 BICC1 PLCE1

2.78e-071741648a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ITGA8 ADAMTS5 SVEP1 FBLN2 FBN1 PDLIM3 C11orf96 BICC1

3.04e-071761648510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A8 LAMA1 KCP ADGB MALRD1 GPC3 PXDNL ASTN2

3.31e-0717816484df6218b20c2f076c22346d23260964cc0d73e65
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

FRAS1 SPNS2 ENC1 CRACR2B HS3ST4 UTY PLCE1 EPHA7

3.31e-07178164835a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 LAMA1 SNRK SMOC2 HPN ASTN2 BICC1 EPHA7

3.76e-0718116489d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF SPNS2 FAM110D SNRK CD320 JAG2 FBLN2 FBN1

3.92e-071821648d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 LAMA1 SNRK SMOC2 HPN ASTN2 BICC1 EPHA7

3.92e-071821648eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TMPRSS15 LAMA1 MUC5B SSPOP MYOM2 PLCE1 EPHA7

4.26e-0718416482cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TMPRSS15 LAMA1 MUC5B SSPOP MYOM2 PLCE1 EPHA7

4.26e-071841648ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TMPRSS15 LAMA1 MUC5B SSPOP MYOM2 PLCE1 EPHA7

4.26e-0718416482b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SPRY1 VWF CRIM1 SPNS2 LRRC1 NOSTRIN NOTCH4 SMAD9

4.44e-071851648f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF SPNS2 CRACR2B C16orf89 FBLN2 PDLIM3 EXOC3L1 NOTCH4

4.62e-071861648b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF SPNS2 CRACR2B C16orf89 FBLN2 PDLIM3 EXOC3L1 NOTCH4

4.62e-0718616488a8ed1502542d4895cba3fd5d534256206578716
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 LAMA1 SNRK SMOC2 HPN ASTN2 BICC1 EPHA7

4.81e-071871648c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

VWF CRIM1 ITPRID2 ADAMTS5 C16orf89 FBLN2 FBN1 PDLIM3

5.01e-0718816482777eb7689b271c199021fe7d9db88ccebff14de
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 SNRK KANSL1 PXDNL ASTN2 PRKN UTY BICC1

5.22e-071891648830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF SPNS2 FAM110D CD320 JAG2 FBLN2 FBN1 NOSTRIN

5.22e-071891648fccadf8efbef17b7f12291b069c71060a71b04e2
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA8 SVEP1 ADCY9 FBN1 GPC3 PXDNL ASTN2 BICC1

5.22e-0718916482a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPRY1 VWF ITGA8 ADAMTS5 JAG2 BRWD1-AS2 NOSTRIN NOTCH4

5.43e-07190164806bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCell15-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

SMOC2 FBLN2 FBN1 GPC3 PDLIM3 HSD11B2 CARNS1 BICC1

5.43e-071901648b47472dc9fe6ed99c2365203a3d8a59879e74a70
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS5 THSD7B SMOC2 SVEP1 FBN1 SPDYA BICC1 PLCE1

5.65e-071911648b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPRY1 ITGA8 ADAMTS5 SVEP1 FBN1 GPC3 ASTN2 BICC1

5.65e-071911648cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 ADAMTS5 SMOC2 SVEP1 FBLN2 FBN1 HSD11B2 SMAD9

6.11e-07193164859b8186d0221fba06a16157e9d148399ed801f38
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELENOP ADAMTS5 SMOC2 SVEP1 FBLN2 FBN1 GPC3 BICC1

6.11e-071931648f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 ADAMTS5 SMOC2 SVEP1 FBLN2 FBN1 HSD11B2 SMAD9

6.11e-071931648dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 ADAMTS5 SMOC2 SVEP1 FBLN2 FBN1 HSD11B2 SMAD9

6.11e-07193164803678162648bd5b1d65a5450b60c8863edbf95c7
ToppCellIPF-Endothelial-VE_Venous|IPF / Disease state, Lineage and Cell class

VWF CRIM1 SPNS2 FAM110D LRRC1 NOSTRIN NOTCH4 SMAD9

6.11e-07193164829a655fa80feaabe846c90a28363b037e22d24ae
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELENOP ADAMTS5 SMOC2 SVEP1 FBLN2 FBN1 GPC3 BICC1

6.11e-07193164885faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCellIPF-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

VWF CRIM1 SPNS2 FAM110D LRRC1 NOSTRIN NOTCH4 SMAD9

6.11e-071931648ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCellfacs-MAT-Fat-3m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELENOP ADAMTS5 SMOC2 SVEP1 FBLN2 FBN1 GPC3 BICC1

6.11e-071931648110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

SPRY1 ADAMTS5 SMOC2 SVEP1 FBLN2 FBN1 IRS2 BICC1

6.36e-071941648014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellIPF-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

SPRY1 VWF SPNS2 FAM110D LRRC1 NOSTRIN NOTCH4 SMAD9

6.61e-071951648120296531bbc8080dcabacbd64733cc1dc34603a
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

VWF CRIM1 SPNS2 PRAG1 JAG2 SLC9C1 NOSTRIN NOTCH4

6.61e-071951648fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF SPNS2 FAM110D SNRK CD320 EXOC3L1 NOSTRIN NOTCH4

6.61e-071951648f65053811074a7f2ff0368f3a63b88e2a08da1a0
ToppCellIPF-Endothelial-VE_Peribronchial|IPF / Disease state, Lineage and Cell class

SPRY1 VWF SPNS2 FAM110D LRRC1 NOSTRIN NOTCH4 SMAD9

6.61e-0719516482c3ad3cb79f11119ac69c413a938d21199145040
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF SPNS2 FAM110D SNRK JAG2 FBLN2 FBN1 NOSTRIN

6.61e-071951648752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ENC1 SMOC2 SVEP1 ZNF469 FBLN2 FBN1 PDLIM3 BICC1

6.87e-071961648525d6c8a277364e624e7cc586275f8a891436b57
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

VWF SPNS2 FAM110D SNRK EPOP NOSTRIN NOTCH4 SMAD9

6.87e-07196164814dd6956ef420b660be0baf52a66960e57d75d16
ToppCellPCW_10-12-Endothelial-Endothelial_mature|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VWF SPNS2 FAM110D THSD7B JAG2 EXOC3L1 NOSTRIN NOTCH4

6.87e-071961648481d79bdaec069ad2746a28d39eeee8d3edf7305
ToppCellASK454-Endothelial-Endothelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

VWF SPNS2 FAM110D SNRK EPOP NOSTRIN NOTCH4 SMAD9

6.87e-0719616482b777a2026b56839112fd179f2db482c49f4594a
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

SPRY1 SELENOP ITGA8 SVEP1 GPC3 PXDNL HPN UTY

7.14e-0719716480a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPRY1 SMOC2 SVEP1 FBLN2 FBN1 GPC3 C11orf96 BICC1

7.14e-071971648ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SPRY1 SELENOP EPB41L4B SMOC2 SVEP1 FBN1 GPC3 BICC1

7.14e-0719716485afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF SPNS2 FAM110D SNRK CD320 EXOC3L1 NOSTRIN NOTCH4

7.14e-071971648131bc6ef55f467cc802db68daf7e7d757ea64fc6
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SPRY1 SELENOP EPB41L4B SMOC2 SVEP1 FBN1 GPC3 BICC1

7.14e-0719716481baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCelldistal-Endothelial-Bronchial_Vessel_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPRY1 VWF FAM110D CD320 FBLN2 LRRC1 NOSTRIN SMAD1

7.14e-071971648f45a93b5ad80a16b760acbaa6467648ffc05a0d3
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

VWF CRIM1 SPNS2 PRAG1 JAG2 SLC9C1 NOSTRIN NOTCH4

7.14e-071971648ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SPRY1 SELENOP EPB41L4B SMOC2 SVEP1 FBN1 GPC3 BICC1

7.14e-071971648b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

VWF SPNS2 FAM110D SNRK JAG2 EXOC3L1 NOSTRIN NOTCH4

7.14e-0719716489b3d6fe76dd7d61a286a28d9466b5f2fece048e1
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPRY1 VWF FAM110D CD320 JAG2 EXOC3L1 NOSTRIN NOTCH4

7.14e-071971648c29ed0e706999d4c2b93e6e3bf46c42aeceb4813
ToppCell390C-Endothelial_cells|390C / Donor, Lineage, Cell class and subclass (all cells)

VWF CRIM1 SPNS2 FAM110D EXOC3L1 NOSTRIN SMAD1 NOTCH4

7.14e-071971648aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCellPCW_10-12-Endothelial-Endothelial_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VWF SPNS2 FAM110D THSD7B JAG2 EXOC3L1 NOSTRIN NOTCH4

7.41e-071981648eac26ed95b4a4343a5dfe1fbecef9374e5947884
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF SPNS2 SNRK CD320 JAG2 EXOC3L1 NOSTRIN NOTCH4

7.41e-071981648ff8a9adc1302a4679ccdfe9ef95ef53e4c7a5391
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

SELENOP ITGA8 SVEP1 FBLN2 FBN1 GPC3 PDLIM3 BICC1

7.41e-0719816482d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF CRIM1 SPNS2 FAM110D CD320 NOSTRIN SMAD1 NOTCH4

7.41e-0719816485b86dc00acf8ac2ede008f5d79c09996485bf250
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF SPNS2 SNRK CD320 JAG2 EXOC3L1 NOSTRIN NOTCH4

7.41e-07198164809e452742aed9f48bf1ffc35c6b06a296bcfe076
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF SPNS2 FAM110D SNRK CD320 EXOC3L1 NOSTRIN NOTCH4

7.41e-07198164837d6557833877fc2ff51fbeb589e3eb832dbef5f
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SPRY1 SELENOP SMOC2 RNF217 SVEP1 FBN1 GPC3 C11orf96

7.41e-071981648a8c21f4db6730d0aa05b61fbe72bf9f7571a9015
ToppCell(6)_Endothelial-A_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SPRY1 VWF CRIM1 SPNS2 FAM110D LRRC1 NOSTRIN NOTCH4

7.41e-07198164844f8cd5afa3685dcc8bfea0b15af5e8817e12e2e
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SPRY1 SELENOP SMOC2 RNF217 SVEP1 FBN1 GPC3 C11orf96

7.41e-0719816488b68fc887e5ad0a59ea4d93dfd1edda67030f142
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF CRIM1 SPNS2 FAM110D CD320 NOSTRIN SMAD1 NOTCH4

7.41e-07198164813203249e5743ba2699871c184d141207e550a86
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VWF SPNS2 FAM110D THSD7B JAG2 EXOC3L1 NOSTRIN NOTCH4

7.41e-0719816485fe186d46c47ea1ca450cf67e8eb01c2c3f7f83c
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SPRY1 SELENOP SMOC2 RNF217 SVEP1 FBN1 GPC3 C11orf96

7.41e-0719816484739b2e4ab141c66772e61686b45614a1839483e
ToppCellASK452-Mesenchymal-Fibroblast|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

SMOC2 SVEP1 FBLN2 FBN1 GPC3 PDLIM3 C11orf96 RNF180

7.70e-0719916484d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCellASK452-Mesenchymal|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

SMOC2 SVEP1 FBLN2 FBN1 GPC3 PDLIM3 C11orf96 RNF180

7.70e-07199164893e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

SPRY1 SELENOP ITGA8 SVEP1 FBN1 GPC3 PXDNL BICC1

7.70e-071991648211c3a08f2d484ab7a3368006767289088f0d957
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPRY1 VWF FAM110D ITGA8 JAG2 EXOC3L1 NOSTRIN NOTCH4

7.70e-0719916480602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPRY1 VWF CRIM1 ITGA8 JAG2 EXOC3L1 NOSTRIN NOTCH4

7.70e-071991648463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

SPRY1 SELENOP ITGA8 SVEP1 FBN1 GPC3 PXDNL BICC1

7.70e-0719916481a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)|367C / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 VWF CRIM1 SPNS2 FAM110D LRRC1 NOSTRIN NOTCH4

7.70e-07199164829ed081bd5204a32068b420f2244f3704891547b
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 SELENOP FRAS1 CRIM1 ITGA8 SVEP1 GPC3 IRS2

7.70e-071991648212e89d097753790061310373a1fafba773488b6
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 VWF CRIM1 SPNS2 FAM110D LRRC1 NOSTRIN NOTCH4

7.70e-071991648c2d85f80037f209a4a329790f475d9f98f590262
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 SELENOP FRAS1 CRIM1 ITGA8 SVEP1 GPC3 IRS2

7.70e-07199164814b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SELENOP LAMA1 ITGA8 SVEP1 FBN1 GPC3 PXDNL BICC1

8.00e-0720016489b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellcellseq-Mesenchymal-Fibroblastic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SELENOP ITGA8 SVEP1 FBLN2 FBN1 GPC3 PDLIM3 BICC1

8.00e-0720016488978867bf69c830b1e48cac2ad6b512dbe60f149
Diseasepulse pressure measurement

PAPPA2 CRIM1 MAEA PCDHA12 SMOC2 ZNF831 SSPOP SNX19 SVEP1 FBN1 MALRD1 KANSL1 MEGF8 ATXN1 PLEKHM2 PXDNL C11orf96 LRRC1 SNX11 BRD1 FHL3 BICC1 PLCE1

2.15e-06139216123EFO_0005763
Diseasemesangial proliferative glomerulonephritis (biomarker_via_orthology)

VWF ITGA8 FBN1

8.75e-0681613DOID:4783 (biomarker_via_orthology)
DiseaseO-methylcatechol sulfate measurement

SPNS2 CARNS1

2.96e-0521612EFO_0022102
DiseaseCOVID-19 symptoms measurement

MUC5B TYK2 KANSL1 LTF

3.92e-05351614EFO_0600019
DiseaseX-24513 measurement

SPNS2 CARNS1

8.84e-0531612EFO_0022133
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN3

8.84e-0531612DOID:65 (implicated_via_orthology)
DiseaseX-21658 measurement

SPNS2 CARNS1

1.76e-0441612EFO_0022121
Diseaselactotransferrin measurement

ACCS LTF

1.76e-0441612EFO_0020526
Diseasehypertension, pregnancy-induced

ZNF831 PLCE1

2.93e-0451612MONDO_0024664
Diseasecentral corneal thickness

FBLN7 CRIM1 SMOC2 BABAM2 ZNF469 FBN1 ATXN1 BICC1

3.11e-043091618EFO_0005213
Diseasecortical surface area measurement

SPRY1 SMOC2 SVEP1 TG JAG2 ZNF469 MTMR11 FBN1 KANSL1 EPOP ASTN2 BRD1 CD180 CDC25C ZBTB18 FBN3 PLCE1 EPHA7

4.14e-04134516118EFO_0010736
Diseasebeta-hydroxybutyric acid measurement

THSD7B NOSTRIN

4.37e-0461612EFO_0010465
Disease2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA) measurement

SPNS2 CARNS1

4.37e-0461612EFO_0800111
Diseasesolute carrier family 22 member 16 measurement

SELENOP MALRD1

4.37e-0461612EFO_0802079
DiseaseIGF-like family receptor 1 measurement

ZBTB32 PROSER3

4.37e-0461612EFO_0801687
Diseasecysteine-rich with EGF-like domain protein 1 measurement

IL17RC BRPF1 BRD1

7.04e-04321613EFO_0021870
Diseasecesarean section, anxiety

ATXN1 DIP2C

8.11e-0481612EFO_0005230, EFO_0009636
Diseasecorneal resistance factor

FBLN7 CRACR2B SMOC2 BABAM2 ZNF469 FBLN2 FBN1 ATXN1 BICC1

8.69e-044511619EFO_0010067
Diseaseschizophrenia (is_implicated_in)

HTR2C ITGA8 BRD1 NOTCH4

8.90e-04781614DOID:5419 (is_implicated_in)
DiseaseIdiopathic pulmonary hypertension

SMAD1 SMAD9

1.04e-0391612C0152171
Diseasepropionylcarnitine measurement

MALRD1 CARNS1

1.04e-0391612EFO_0020942
Diseasevisceral heterotaxy (implicated_via_orthology)

AP1B1 MEGF8 BICC1

1.08e-03371613DOID:0050545 (implicated_via_orthology)
Diseasecortical thickness

FBLN7 CRIM1 LAMA1 SMOC2 TG JAG2 ZNF469 FBN1 ZBTB32 MALRD1 KANSL1 MTMR3 ASTN2 PLCE1 EPHA7

1.18e-03111316115EFO_0004840
DiseaseDegenerative Diseases, Central Nervous System

SELENOP ATXN1 HCRT

1.26e-03391613C0270715
DiseaseNeurodegenerative Disorders

SELENOP ATXN1 HCRT

1.26e-03391613C0524851
DiseaseDegenerative Diseases, Spinal Cord

SELENOP ATXN1 HCRT

1.26e-03391613C0751733
Diseaseresponse to anticoagulant

SMOC2 EPHA7 ZNF646

1.46e-03411613GO_0061476
Diseasemicrophthalmia (implicated_via_orthology)

CRIM1 MFRP

1.88e-03121612DOID:10629 (implicated_via_orthology)
Diseasethyroid stimulating hormone measurement

AEN SPPL3 ITGA8 CD320 SMOC2 ADCY9 TG

2.05e-033231617EFO_0004748
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

SMAD1 SMAD9

2.22e-03131612DOID:0050787 (implicated_via_orthology)
DiseaseSkin Abnormalities

ZNF469 AP1B1

2.22e-03131612C0037268
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

SMAD1 SMAD9

2.58e-03141612C1150929
Diseaseretinal drusen

VWF PRR18 SVEP1

2.74e-03511613EFO_1001155
Diseaselymphocyte count

INHBE FRAS1 ENC1 SPPL3 ZNF831 ADCY9 TYK2 ZNF469 FBN1 MTHFD1 CDK13 NLRC5 PRKN CHST2 NOSTRIN FUT7 PLCE1

2.75e-03146416117EFO_0004587
Diseasebody surface area

PAPPA2 CRIM1 EPB41L4B SMOC2 ADCY9 FBLN2 MTMR11 FBN1 MTMR3 ASTN2

2.89e-0364316110EFO_0022196
DiseaseInherited oocyte maturation defect

ZP2 FBXO43

3.38e-03161612cv:CN238505
Diseasepreeclampsia, hypertension, pregnancy-induced

ZNF831 PLCE1

3.38e-03161612EFO_0000668, MONDO_0024664
DiseaseIdiopathic pulmonary arterial hypertension

SMAD1 SMAD9

3.38e-03161612C3203102
Diseasephysical activity measurement, body mass index

TBKBP1 ADCY9 ASTN2 PRKN

3.58e-031141614EFO_0004340, EFO_0008002
Diseaselymphocyte percentage of leukocytes

TSPOAP1 TSPAN32 ZNF831 ADCY9 TYK2 KANSL1 ATXN1 CDK13 NLRC5 NOTCH4

3.67e-0366516110EFO_0007993
DiseaseFamilial primary pulmonary hypertension

SMAD1 SMAD9

3.81e-03171612C0340543
DiseaseWithdrawal Symptoms

HTR2C HCRT SMAD1

3.95e-03581613C0087169
DiseaseDrug Withdrawal Symptoms

HTR2C HCRT SMAD1

3.95e-03581613C0086189
DiseaseSubstance Withdrawal Syndrome

HTR2C HCRT SMAD1

3.95e-03581613C0038587
Diseaseaspartate aminotransferase measurement

FBLN7 SPPL3 THSD7B PRAG1 HARS2 AP1B1 ATXN1 NLRC5 ASTN2 NOSTRIN NOTCH4 PLCE1

4.12e-0390416112EFO_0004736
Diseaseischemia (biomarker_via_orthology)

MUC13 MUC2

4.27e-03181612DOID:326 (biomarker_via_orthology)
DiseaseLipoidosis

INHBE HPN

4.76e-03191612C0023794
Diseaselongevity

MFRP PRR18 SVEP1 MTHFD1 PRDM13 NOTCH4

4.80e-032841616EFO_0004300
DiseaseCocaine Abuse

HTR2C TYK2 HCRT SMAD1

5.25e-031271614C0009171
Diseaseglomerulonephritis (biomarker_via_orthology)

FBN1 SMAD1

5.27e-03201612DOID:2921 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

SELENOP LAMA1 FBLN2 SACS FCN2 DIP2C FHL3 MUTYH EPHA7 SMAD9

5.34e-0370216110C0009402

Protein segments in the cluster

PeptideGeneStartEntry
CLSRPTAPKSGACLA

nan

46

A8MZ25
KCPPNASGSASRRCL

ADGRB2

556

O60241
KASGPLPSKCVAIDC

AEN

101

Q8WTP8
ALAPASCLPSGSCAR

EXOC3L1

726

Q86VI1
TPSAKRCILCNFLPG

BRWD1-AS2

21

P59051
SPLCDSSFNAPKCGR

BRD1

861

O95696
QTLCKTPPRSLSAGA

CEP152

1236

O94986
PCGLSDLCRSLMTKP

C16orf89

176

Q6UX73
QKDFRAPTTCLGPTC

ACCS

6

Q96QU6
LPCLSRDSPCNSFAI

ADGB

1091

Q8N7X0
KGCPLSQRPSAFKQC

ADAMTS5

911

Q9UNA0
PPGLSLDFLKCCKRN

HTR2C

256

P28335
TALLCQELGLPCSSP

CARNS1

481

A5YM72
PGNPSCTDLELSLKC

AP1B1

916

Q10567
CPERTSQLFDLPCSK

ATXN1

661

P54253
LNSPGAIELRTCCSP

HSD11B2

116

P80365
TCANPPSLRGVKLSD

CD180

606

Q99467
TNLCLNGRCLPTPSS

FBN3

416

Q75N90
ASCPAGLACPSLDIL

BICC1

431

Q9H694
AQLELISRICGSPCP

CDK13

921

Q14004
TCHLCRRPGKEQLSP

ASTN2

986

O75129
PASCPDVSSCRGSLR

MUC5B

5631

Q9HC84
ALEPGLASCLSPKCL

TSPOAP1

1481

O95153
LGSVLPPCRSVCQEA

MFRP

531

Q9BY79
LACPEPRASQNCLSK

FBLN7

16

Q53RD9
SHCTACSPPKALRQG

FRAS1

621

Q86XX4
SPDCPVCSRSLNKLA

MAEA

311

Q7L5Y9
QPSSCLASRCLPGEQ

MTMR11

36

A4FU01
DLQVCLPKGPTCCSR

GPC3

61

P51654
SAQCPLGQRCLEKAP

JAG2

921

Q9Y219
PTKFQCRTSGLCVPL

CD320

56

Q9NPF0
LQASLKSCPRPASVC

KRT32

11

Q14532
ASLCPCQSVKFRPGL

DUX5

11

Q96PT3
PGSSPCTDALTCIKA

TMPRSS15

186

P98073
CPSCGGSKLAPQAER

INHBE

26

P58166
SLSEPCRPGFSCINT

FBLN2

816

P98095
RTATLCPKTCPGNLV

MUC2

286

Q02817
DCTPSPLCQLIKDSL

MUC2

4686

Q02817
NGRPLCASCLVPTVA

FUT7

206

Q11130
PCRLLSSPEACNQSG

MEGF8

1876

Q7Z7M0
STIRPGCDVNPSCAL

KANSL1

621

Q7Z3B3
KSPHILCSQPNACSR

KLKP1

36

Q107X0
ASPDCITILCKPNGQ

LMNTD1

231

Q8N9Z9
NCCEEKRNPSSSTLP

GGA2

391

Q9UJY4
CPCGNRSISLDRLPN

MCM10

816

Q7L590
CKRLLPLATTGDGNC

OTUD7A

196

Q8TE49
LTKDPRLACVLGTPC

RFPL4B

126

Q6ZWI9
ADVSPINCSLCLKPD

NPEPPSL1

56

A6NEC2
LRDCNSLPGVLGTCK

EPHA7

106

Q15375
LLSLCTPNSLPSGCE

HUWE1

951

Q7Z6Z7
CGSRSADNLSCPSPL

ITPRID2

1051

P28290
GSQAPLIAPLCCAAA

ITGA8

11

P53708
PCCSRPKVAALTAGT

HPN

11

P05981
SEPTCQENLPRCGAL

LRRC1

421

Q9BTT6
LPTFLAGLASCTCRP

NLRC5

561

Q86WI3
CSPAQLLCSTPNGLD

CDC25C

121

P30307
ENCTIALPECGKAPR

PRSS36

316

Q5K4E3
CCRSRKKGPISQPLD

PLA2G4E

286

Q3MJ16
LFTDEALKPCPRCQS

FBXO43

631

Q4G163
SLAATPPAAKCSSCR

IRS2

346

Q9Y4H2
FQDCSPLLSPERKCT

MALRD1

1251

Q5VYJ5
PASCLLSCNQRSLPA

NT5DC4

406

Q86YG4
IHRPCGKQDSCPSLL

PAPPA2

1386

Q9BXP8
LSGCTARRPLPNCSN

PXDNL

706

A1KZ92
LFAPKCSSCKRPIVG

FHL3

216

Q13643
AASAPSSLLDQPCLC

HDAC10

391

Q969S8
KSGCTSLTPGPNCDR

BABAM2

41

Q9NXR7
RKPCRGTQEFSPLCL

EPOP

26

A6NHQ4
QPCLTGPRTCKDLLD

FCN2

96

Q15485
PRKCAPGTCQNLDGS

FBN1

1981

P35555
LPAPCASKVELRLSC

CPNE7

16

Q9UBL6
KALTTARLPGPTCCC

CRACR2B

366

Q8N4Y2
PPACGELSNCTLTGK

CRIM1

466

Q9NZV1
KGLRQEVICPCASSP

DIP2C

641

Q9Y2E4
NLKTCPSCGITFAPK

ADCY9

626

O60503
IPSPRKEFSACAIGC

ENC1

326

O14682
LAPAPRSGECLCLTD

EMC9

31

Q9Y3B6
PEPAAAKCLTQSTCL

FHIP2A

291

Q5W0V3
SLPRSACLCSRNSAP

RTL8C

56

O15255
LKCKVCLRPFGDPSN

PRDM13

601

Q9H4Q3
SSPDTNCHIGKLPCR

SACS

3106

Q9NZJ4
DFRDSKLQCCPGPTS

EPB41L4B

831

Q9H329
GPCPDSAARFCLNLT

PRR18

126

Q8N4B5
ARGDLNDCFIPCTPK

MTHFD1

136

P11586
RKPACAQSLLPCSVA

C18orf63

351

Q68DL7
CLKKPEDSSAPRCLG

HS3ST4

396

Q9Y661
CALEPSGCTSLPSKA

IL17RC

481

Q8NAC3
DTRCPKPASQIGCSA

WDR77

196

Q9BQA1
TRSPCALPLAECKEG

MTMR3

911

Q13615
VVCGPCSEKRFLLPS

PLEKHF2

181

Q9H8W4
ESCTSPCLLGAPRKA

PRR14L

1481

Q5THK1
GRSSCQPRKPALDLS

PCARE

911

A6NGG8
RCAPGKPTLVCSSAV

PCDHA12

731

Q9UN75
CLRTLAKDNPSSTPC

RNF180

456

Q86T96
PAPGAAQLSSRLCKA

NOSTRIN

431

Q8IVI9
LLSSGAAAQPLPDCC

HCRT

26

O43612
CQLKRDQPSPCLSSA

PLEKHM2

551

Q8IWE5
CLPSGAARPSETTLC

F12

486

P00748
ICPSSTEVLKACRNP

UTY

836

O14607
PSATPVDCSLCGKKR

SPDYA

221

Q5MJ70
LSSPLCCDFGRPKEG

SNX11

226

Q9Y5W9
CQALCMRLPEASGPS

RIN1

101

Q13671
LSQLLRPPCASCTGA

HARS2

16

P49590
VPISSCRCGLPSANA

SSPOP

4721

A2VEC9
SLPCVAGCPNSLIKE

PRKN

286

O60260
ATARSPQPCSLLGTK

SLC9C1

1146

Q4G0N8
SCAPGSDPRSNLCAL

LTF

511

P02788
RDLGTPECQSSLPCL

PLCE1

561

Q9P212
PLPCKLQVTERGSCC

KCP

941

Q6ZWJ8
TFALRADNPLGCSPC

LAMA1

1136

P25391
QKLSCCPTCRGALTP

SIAH2

106

O43255
ETCNSPPCGAKDSLI

SPNS2

351

Q8IVW8
ELGATVCTPQRPLCS

MUTYH

281

Q9UIF7
RITPGSKAAAANLCP

PDLIM3

31

Q53GG5
IRKSEATPSPGACLQ

PROSER3

336

Q2NL68
FCCGPSPLTAIRKGD

TGM4

361

P49221
SCCLLSPDANVKAAP

SPATA3

81

Q8NHX4
LGRIDSSTKPCPQCK

RNF217

336

Q8TC41
PGKNISCRCDPSEIN

SLC4A8

1051

Q2Y0W8
GLKNFPCTPESLCDV

SNUPN

231

O95149
SAIGCASRCLPNSKL

THAP6

6

Q8TBB0
QTSAKCEKISCGPPA

SVEP1

3406

Q4LDE5
GPLCNLPLSSCQKAA

NOTCH4

876

Q99466
RNPKEGLLCASSPAS

SNRK

746

Q9NRH2
AGKRALCPTCSLPLS

FAM110D

146

Q8TAY7
ITUQCKENLPSLCSU

SELENOP

316

P49908
ERALSCPGQPSKCVT

SMAD9

56

O15198
LEKALSCPGQPSNCV

SMAD1

51

Q15797
LQSPSRAVDCALCPN

BRPF1

321

P55201
GAATNKVVCSSPLCP

CHST2

251

Q9Y4C5
GKDPCCSLRPLSNSV

C11orf96

36

Q7Z7L8
SLDISCKCVNTDLPP

ZNF665

46

Q9H7R5
CPECGKAFISLPSVR

ZNF564

171

Q8TBZ8
SPSSALRLCCAGPSQ

nan

91

Q96NJ1
NLETPTGLKPCDCSV

ZNF490

146

Q9ULM2
KLECRKTTCNPCPLG

VWF

2616

P04275
GLACDCKSDLQRPNP

MUC13

341

Q9H3R2
SLDCAGSPQKPLCAS

SMOC2

41

Q9H3U7
ACGRQPQEPSLLRCS

TSPAN32

241

Q96QS1
LTRPCSPQNKISFGC

SPPL3

121

Q8TCT6
SKPAADVNVPTCSLC

ZBTB18

401

Q99592
GLCALAGSEKPSPCQ

TFF2

16

Q03403
AGSEKPSPCQCSRLS

TFF2

21

Q03403
RPGEATSAQPFLCCL

ZNF646

871

O15015
PGRNKAKSTCSCPDL

NRDC

51

O43847
KCKCGECTAPRTLPS

SPRY1

186

O43609
SQCPKNAPCSLAILS

TRBV23-1

86

A0A0A0MS06
DRRILSGSCPDPKCQ

VCPIP1

41

Q96JH7
ILDCCPGSPVAKAAS

PRAG1

256

Q86YV5
CPSRPSCLEKDLTND

SNX19

476

Q92543
LTTSPCDPKEALAGC

ZNF469

2171

Q96JG9
PCKPSCVSQLGQRAE

ZNF333

46

Q96JL9
AQCTPCGKRSLPVDS

ZNF786

296

Q8N393
PCPDCGKAFVRSSDL

ZNF648

336

Q5T619
NCSLLPADPASVLCS

SRY

141

Q05066
ASCARPILPAQGCET

WTIP

351

A6NIX2
TGEKPFSCSLCPQRS

ZBTB32

396

Q9Y2Y4
DSILKQLCSVPCPGD

THSD7B

1356

Q9C0I4
CCLSRSVPLPAEQKA

ZNF831

1186

Q5JPB2
SGLCSNDCPRKITPF

ITFG1

446

Q8TB96
SDIRSCPLCQLGFPV

TBKBP1

581

A7MCY6
KLSLCVAPGKACSPA

TREX1

66

Q9NSU2
AKCLPNSPCSLEIQA

TRBV16

86

A0A087WV62
SKLPTCPGSCEEAKL

TG

916

P01266
SALICNRLSPDSPLC

ZP2

616

Q05996
KAGLPAQTALPCDIC

ZNF134

41

P52741
SLRRCCLPQPGETSN

TYK2

546

P29597
GSRCDNSSCSKLPPQ

USP54

1001

Q70EL1
SATVAAKGHPCLRCP

NAA30

61

Q147X3
CGKSASPLKVLCTPE

MYOM2

1231

P54296