Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ceramide floppase activity	ABCB1 ABCB4	2.07e-05	3	53	2	GO:0099038
GeneOntologyMolecularFunction	sphingolipid floppase activity	ABCB1 ABCB4	4.13e-05	4	53	2	GO:0046623
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCB1 ABCB4	1.92e-04	8	53	2	GO:0090554
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCG4 ABCB1 ABCB4	2.98e-04	49	53	3	GO:0140359
GeneOntologyMolecularFunction	muscle alpha-actinin binding	PKD2 PKD2L1	7.10e-04	15	53	2	GO:0051371
GeneOntologyMolecularFunction	floppase activity	ABCB1 ABCB4	8.10e-04	16	53	2	GO:0140328
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCG4 SLC38A9 SLC26A5 PKD2 PKD2L1 GRIA1 SLC45A2 SLC44A4 ABCB1 ABCB4	9.50e-04	1180	53	10	GO:0022857
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC38A9 SLC26A5 GRIA1 SLC44A4 ABCB1	1.06e-03	293	53	5	GO:0008514
GeneOntologyMolecularFunction	sphingolipid transporter activity	ABCB1 ABCB4	1.27e-03	20	53	2	GO:0046624
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCB1 ABCB4	1.27e-03	20	53	2	GO:0008525
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCG4 SLC26A5 SLC45A2 SLC44A4 ABCB1 ABCB4	1.60e-03	477	53	6	GO:0022804
GeneOntologyMolecularFunction	transporter activity	ABCG4 SLC38A9 SLC26A5 PKD2 PKD2L1 GRIA1 SLC45A2 SLC44A4 ABCB1 ABCB4	1.85e-03	1289	53	10	GO:0005215
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC38A9 SLC26A5 GRIA1 ABCB1	2.21e-03	207	53	4	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC38A9 SLC26A5 GRIA1 ABCB1	2.25e-03	208	53	4	GO:0005342
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCB1 ABCB4	2.50e-03	28	53	2	GO:0140326
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	EDEM3 MGAM OTOG	2.59e-03	103	53	3	GO:0004553
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCG4 ABCB1 ABCB4	3.04e-03	109	53	3	GO:0042626
GeneOntologyMolecularFunction	alpha-actinin binding	PKD2 PKD2L1	3.06e-03	31	53	2	GO:0051393
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	PKD2 GRIA1	3.06e-03	31	53	2	GO:0099604
GeneOntologyBiologicalProcess	response to water	PKD2 PKD2L1 PLEC	5.39e-06	14	52	3	GO:0009415
GeneOntologyBiologicalProcess	cellular response to hydrostatic pressure	PKD2 PLEC	1.87e-05	3	52	2	GO:0071464
GeneOntologyBiologicalProcess	ceramide translocation	ABCB1 ABCB4	1.87e-05	3	52	2	GO:0099040
GeneOntologyBiologicalProcess	sphingolipid translocation	ABCB1 ABCB4	6.20e-05	5	52	2	GO:0099039
GeneOntologyBiologicalProcess	cellular response to water stimulus	PKD2 PLEC	9.29e-05	6	52	2	GO:0071462
GeneOntologyBiologicalProcess	hemidesmosome assembly	LAMA3 PLEC	9.29e-05	6	52	2	GO:0031581
GeneOntologyBiologicalProcess	response to hydrostatic pressure	PKD2 PLEC	1.30e-04	7	52	2	GO:0051599
GeneOntologyBiologicalProcess	response to acid chemical	SLC38A9 PKD2 PKD2L1 GRIA1 PLEC	2.69e-04	228	52	5	GO:0001101
GeneOntologyBiologicalProcess	peptide modification	LANCL3 LANCL2	2.77e-04	10	52	2	GO:0031179
GeneOntologyCellularComponent	membrane attack complex	C8A C9	1.31e-04	7	53	2	GO:0005579
GeneOntologyCellularComponent	apical plasma membrane	MGAM PLEC SLC44A4 USH2A OTOG ABCB1 ABCB4	2.18e-04	487	53	7	GO:0016324
GeneOntologyCellularComponent	intercellular canaliculus	ABCB1 ABCB4	2.24e-04	9	53	2	GO:0046581
GeneOntologyCellularComponent	hemidesmosome	LAMA3 PLEC	3.42e-04	11	53	2	GO:0030056
GeneOntologyCellularComponent	insulin-responsive compartment	RAB4B RAB4A	3.42e-04	11	53	2	GO:0032593
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	ABCG4 MGAM RAB4B SLC38A9 SEC23IP PKD2 GRIA1 SLC45A2 ASB14 PCSK4 RAB4A	3.66e-04	1307	53	11	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	ABCG4 MGAM RAB4B SLC38A9 SEC23IP PKD2 GRIA1 SLC45A2 ASB14 PCSK4 RAB4A	4.11e-04	1325	53	11	GO:0012506
GeneOntologyCellularComponent	apical part of cell	MGAM PLEC SLC44A4 USH2A OTOG ABCB1 ABCB4	7.02e-04	592	53	7	GO:0045177
GeneOntologyCellularComponent	condensed nuclear chromosome	NEK2 RSPH1 ADD3	1.60e-03	91	53	3	GO:0000794
Domain	LANC_like	LANCL3 LANCL2	2.28e-05	3	52	2	PF05147
Domain	LanC-like_prot_euk	LANCL3 LANCL2	2.28e-05	3	52	2	IPR020464
Domain	LANC-like	LANCL3 LANCL2	2.28e-05	3	52	2	IPR007822
Domain	LANC_like	LANCL3 LANCL2	2.28e-05	3	52	2	SM01260
Domain	PKD_2	PKD2 PKD2L1	7.56e-05	5	52	2	IPR003915
Domain	MACPF_CS	C8A C9	1.13e-04	6	52	2	IPR020863
Domain	Gal_Oxidase_b-propeller	KLHL10 KLHL28 KLHDC10	1.15e-04	34	52	3	IPR015916
Domain	MACPF_2	C8A C9	1.58e-04	7	52	2	PS51412
Domain	MACPF_1	C8A C9	1.58e-04	7	52	2	PS00279
Domain	LAM_G_DOMAIN	FAT3 LAMA3 USH2A	1.60e-04	38	52	3	PS50025
Domain	LDLR_class-A_CS	LRP12 C8A C9	1.87e-04	40	52	3	IPR023415
Domain	Laminin_G_2	FAT3 LAMA3 USH2A	1.87e-04	40	52	3	PF02210
Domain	6hp_glycosidase	LANCL3 LANCL2	2.11e-04	8	52	2	IPR012341
Domain	-	LANCL3 LANCL2	2.11e-04	8	52	2	1.50.10.10
Domain	ABC_transporter_CS	ABCG4 ABCB1 ABCB4	2.16e-04	42	52	3	IPR017871
Domain	LamG	FAT3 LAMA3 USH2A	2.49e-04	44	52	3	SM00282
Domain	Ldl_recept_a	LRP12 C8A C9	2.66e-04	45	52	3	PF00057
Domain	-	LRP12 C8A C9	2.84e-04	46	52	3	4.10.400.10
Domain	LDLRA_1	LRP12 C8A C9	3.22e-04	48	52	3	PS01209
Domain	ABC_tran	ABCG4 ABCB1 ABCB4	3.22e-04	48	52	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCG4 ABCB1 ABCB4	3.22e-04	48	52	3	PS50893
Domain	MAC_perforin	C8A C9	3.37e-04	10	52	2	IPR001862
Domain	ABC_TRANSPORTER_1	ABCG4 ABCB1 ABCB4	3.43e-04	49	52	3	PS00211
Domain	LDLRA_2	LRP12 C8A C9	3.43e-04	49	52	3	PS50068
Domain	LDrepeatLR_classA_rpt	LRP12 C8A C9	3.43e-04	49	52	3	IPR002172
Domain	LDLa	LRP12 C8A C9	3.43e-04	49	52	3	SM00192
Domain	ABC_transporter-like	ABCG4 ABCB1 ABCB4	3.64e-04	50	52	3	IPR003439
Domain	MACPF	C8A C9	4.11e-04	11	52	2	PF01823
Domain	PKD_channel	PKD2 PKD2L1	4.11e-04	11	52	2	PF08016
Domain	PKD1_2_channel	PKD2 PKD2L1	4.11e-04	11	52	2	IPR013122
Domain	MACPF	C8A C9	4.93e-04	12	52	2	SM00457
Domain	MACPF	C8A C9	4.93e-04	12	52	2	IPR020864
Domain	Laminin_G	FAT3 LAMA3 USH2A	5.64e-04	58	52	3	IPR001791
Domain	Kelch	KLHL10 KLHL28 KLHDC10	5.64e-04	58	52	3	SM00612
Domain	6-hairpin_glycosidase-like	LANCL3 LANCL2	5.82e-04	13	52	2	IPR008928
Domain	EGF-like_dom	FAT3 LAMA3 C8A C9 OTOG	6.31e-04	249	52	5	IPR000742
Domain	EGF_1	FAT3 LAMA3 C8A C9 USH2A	7.02e-04	255	52	5	PS00022
Domain	Laminin_N	LAMA3 USH2A	8.90e-04	16	52	2	IPR008211
Domain	LAMININ_NTER	LAMA3 USH2A	8.90e-04	16	52	2	PS51117
Domain	Laminin_N	LAMA3 USH2A	8.90e-04	16	52	2	PF00055
Domain	LamNT	LAMA3 USH2A	8.90e-04	16	52	2	SM00136
Domain	Growth_fac_rcpt_	LAMA3 C8A C9 PCSK4	9.28e-04	156	52	4	IPR009030
Domain	Kelch_1	KLHL10 KLHL28 KLHDC10	9.77e-04	70	52	3	PF01344
Domain	Kelch_1	KLHL10 KLHL28 KLHDC10	9.77e-04	70	52	3	IPR006652
Domain	ABC_membrane	ABCB1 ABCB4	2.02e-03	24	52	2	PF00664
Domain	-	FAT3 LAMA3 USH2A	2.35e-03	95	52	3	2.60.120.200
Domain	-	KLHL10 KLHL28	2.55e-03	27	52	2	2.130.10.80
Domain	ABC_TM1F	ABCB1 ABCB4	2.74e-03	28	52	2	PS50929
Domain	ABC1_TM_dom	ABCB1 ABCB4	2.74e-03	28	52	2	IPR011527
Domain	EGF_LAM_2	LAMA3 USH2A	3.15e-03	30	52	2	PS50027
Domain	EGF_LAM_1	LAMA3 USH2A	3.15e-03	30	52	2	PS01248
Domain	Thioredoxin	DNAJC16 TXNDC16	3.36e-03	31	52	2	PF00085
Domain	EGF_3	FAT3 C8A C9 OTOG	4.12e-03	235	52	4	PS50026
Domain	Laminin_EGF	LAMA3 USH2A	4.27e-03	35	52	2	PF00053
Domain	EGF_Lam	LAMA3 USH2A	4.27e-03	35	52	2	SM00180
Domain	Laminin_EGF	LAMA3 USH2A	5.01e-03	38	52	2	IPR002049
Domain	Thioredoxin_domain	DNAJC16 TXNDC16	5.82e-03	41	52	2	IPR013766
Domain	EGF-like_CS	FAT3 LAMA3 C8A C9	5.96e-03	261	52	4	IPR013032
Pathway	BIOCARTA_MRP_PATHWAY	ABCB1 ABCB4	9.45e-05	6	36	2	M22078
Pathway	KEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION	C8A C9	1.32e-04	7	36	2	M47873
Pathway	REACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT	C8A C9	1.76e-04	8	36	2	M27006
Pathway	REACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT	C8A C9	1.76e-04	8	36	2	MM14656
Pathway	KEGG_ABC_TRANSPORTERS	ABCG4 ABCB1 ABCB4	1.89e-04	44	36	3	M11911
Pathway	BIOCARTA_ALTERNATIVE_PATHWAY	C8A C9	2.26e-04	9	36	2	M22072
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION	C8A C9	2.26e-04	9	36	2	M47881
Pathway	REACTOME_MET_RECEPTOR_RECYCLING	RAB4B RAB4A	2.82e-04	10	36	2	M27777
Pathway	REACTOME_MET_RECEPTOR_RECYCLING	RAB4B RAB4A	2.82e-04	10	36	2	MM15516
Pathway	REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY	LAMA3 PLEC	3.44e-04	11	36	2	M27372
Pathway	WP_COMPLEMENTMEDIATED_INFLAMMATION_OF_PULMONARY_ALVEOLUS_IN_COVID19_HYPOTHETICAL_PATHWAY	C8A C9	4.12e-04	12	36	2	M48316
Pathway	BIOCARTA_LECTIN_PATHWAY	C8A C9	4.86e-04	13	36	2	M4732
Pathway	BIOCARTA_CLASSIC_PATHWAY	C8A C9	6.52e-04	15	36	2	M7146
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C8A C9	8.42e-04	17	36	2	MM15944
Pathway	REACTOME_SIGNALING_BY_MET	RAB4B LAMA3 RAB4A	1.06e-03	79	36	3	M27643
Pathway	BIOCARTA_COMP_PATHWAY	C8A C9	1.17e-03	20	36	2	M917
Pathway	WP_COMPLEMENT_ACTIVATION	C8A C9	1.42e-03	22	36	2	M39502
Pathway	WP_ALLOGRAFT_REJECTION	C8A C9 ABCB1	1.49e-03	89	36	3	M39398
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCG4 ABCB1 ABCB4	2.03e-03	99	36	3	MM14986
Pathway	WP_INTRACELLULAR_TRAFFICKING_PROTEINS_INVOLVED_IN_CMT_NEUROPATHY	RAB4B RAB4A	2.14e-03	27	36	2	M39899
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCG4 ABCB1 ABCB4	2.27e-03	103	36	3	M758
Pathway	WP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT	ABCB1 ABCB4	2.47e-03	29	36	2	M45551
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCB1 ABCB4	2.64e-03	30	36	2	MM15866
Pubmed	Temporal/spatial expression and efflux activity of ABC transporter, P-glycoprotein/Abcb1 isoforms and Bcrp/Abcg2 during early murine development.	ABCG4 ABCB1 ABCB4	3.33e-08	5	53	3	16458078
Pubmed	Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.	ABCB1 ABCB4	2.28e-06	2	53	2	10488067
Pubmed	Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.	ABCB1 ABCB4	2.28e-06	2	53	2	21705081
Pubmed	The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.	ABCB1 ABCB4	2.28e-06	2	53	2	10552998
Pubmed	Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.	ABCB1 ABCB4	2.28e-06	2	53	2	28441502
Pubmed	Genetic dissection of the function of mammalian P-glycoproteins.	ABCB1 ABCB4	2.28e-06	2	53	2	9196326
Pubmed	MDR1 and MDR3 genes and drug resistance to cisplatin of ovarian cancer cells.	ABCB1 ABCB4	2.28e-06	2	53	2	18231753
Pubmed	Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.	ABCB1 ABCB4	2.28e-06	2	53	2	22184139
Pubmed	Isolation and expression of a complementary DNA that confers multidrug resistance.	ABCB1 ABCB4	2.28e-06	2	53	2	3022150
Pubmed	ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans.	ABCB1 ABCB4	2.28e-06	2	53	2	32058310
Pubmed	Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.	ABCB1 ABCB4	2.28e-06	2	53	2	2570420
Pubmed	MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.	ABCB1 ABCB4	2.28e-06	2	53	2	8898203
Pubmed	Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes.	ABCB1 ABCB4	2.28e-06	2	53	2	2473069
Pubmed	Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.	ABCB1 ABCB4	2.28e-06	2	53	2	28274756
Pubmed	Novel autosomal recessive LAMA3 and PLEC variants underlie junctional epidermolysis bullosa generalized intermediate and epidermolysis bullosa simplex with muscular dystrophy in two consanguineous families.	LAMA3 PLEC	2.28e-06	2	53	2	29797489
Pubmed	A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.	ABCB1 ABCB4	2.28e-06	2	53	2	19185004
Pubmed	Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins.	ABCB1 ABCB4	2.28e-06	2	53	2	3768958
Pubmed	Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.	PKD2 PKD2L1	2.28e-06	2	53	2	29899465
Pubmed	Binding of human complement C8 to C9: role of the N-terminal modules in the C8 alpha subunit.	C8A C9	2.28e-06	2	53	2	12463754
Pubmed	Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice.	ABCB1 ABCB4	2.28e-06	2	53	2	38522903
Pubmed	Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.	ABCB1 ABCB4	2.28e-06	2	53	2	3477522
Pubmed	Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.	ABCB1 ABCB4	2.28e-06	2	53	2	18215618
Pubmed	Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study.	ABCB1 ABCB4	2.28e-06	2	53	2	16857572
Pubmed	Rab4 interacts with the human P-glycoprotein and modulates its surface expression in multidrug resistant K562 cells.	RAB4A ABCB1	2.28e-06	2	53	2	20209493
Pubmed	Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2.	PKD2 PKD2L1	2.28e-06	2	53	2	20408813
Pubmed	Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.	ABCB1 ABCB4	2.28e-06	2	53	2	1969609
Pubmed	Expression of MDR1 and MDR3 gene products in paclitaxel-, doxorubicin- and vincristine-resistant cell lines.	ABCB1 ABCB4	2.28e-06	2	53	2	24140176
Pubmed	Analysis of the specific association of the eighth and ninth components of human complement: identification of a direct role for the alpha subunit of C8.	C8A C9	2.28e-06	2	53	2	4063341
Pubmed	Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis.	ABCB1 ABCB4	2.28e-06	2	53	2	9419367
Pubmed	Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.	ABCB1 ABCB4	2.28e-06	2	53	2	2248681
Pubmed	The role of multiple drug resistance proteins in fetal and/or placental protection against teratogen-induced orofacial clefting.	ABCB1 ABCB4	2.28e-06	2	53	2	17440929
Pubmed	Amplification of the murine mdr2 gene and a reconsideration of the structure of the murine mdr gene locus.	ABCB1 ABCB4	2.28e-06	2	53	2	7832992
Pubmed	Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.	ABCB1 ABCB4	2.28e-06	2	53	2	11826402
Pubmed	What have we learnt thus far from mice with disrupted P-glycoprotein genes?	ABCB1 ABCB4	2.28e-06	2	53	2	8763339
Pubmed	Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.	ABCB1 ABCB4	2.28e-06	2	53	2	9473291
Pubmed	mdr1a-encoded P-glycoprotein is not required for peripheral T cell proliferation, cytokine release, or cytotoxic effector function in mice.	ABCB1 ABCB4	2.28e-06	2	53	2	10453001
Pubmed	The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.	ABCB1 ABCB4	2.28e-06	2	53	2	2471060
Pubmed	The DNA sequence of human chromosome 7.	MGAM DPP6 PDK4 SLC26A5 LANCL2 ABCB1 ABCB4	4.68e-06	441	53	7	12853948
Pubmed	Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.	ABCB1 ABCB4	6.83e-06	3	53	2	7814632
Pubmed	Immunolocalization of ABC drug transporters in human placenta from normal and gestational diabetic pregnancies.	ABCB1 ABCB4	6.83e-06	3	53	2	25029804
Pubmed	LanCL proteins are not Involved in Lanthionine Synthesis in Mammals.	LANCL3 LANCL2	6.83e-06	3	53	2	28106097
Pubmed	Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1).	ABCB1 ABCB4	6.83e-06	3	53	2	9778357
Pubmed	Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9.	C8A C9	6.83e-06	3	53	2	21507937
Pubmed	Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort.	ABCB1 ABCB4	6.83e-06	3	53	2	24732756
Pubmed	Polycystin-2 interacts with troponin I, an angiogenesis inhibitor.	PKD2 PKD2L1	6.83e-06	3	53	2	12525172
Pubmed	LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome.	LANCL3 LANCL2	6.83e-06	3	53	2	33932340
Pubmed	Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine.	ABCB1 ABCB4	6.83e-06	3	53	2	8547326
Pubmed	Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell subsets from healthy donors and HIV-infected patients.	ABCB1 ABCB4	6.83e-06	3	53	2	9542318
Pubmed	Polycystin-2 expression and function in adult mouse lacrimal acinar cells.	PKD2 PKD2L1	6.83e-06	3	53	2	21508103
Pubmed	Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization in adipocyte.	RAB4B RAB4A	6.83e-06	3	53	2	19590752
Pubmed	Structural and functional characterization of the mouse multidrug resistance gene family.	ABCB1 ABCB4	6.83e-06	3	53	2	1980424
Pubmed	Specific association of the gene product of PKD2 with the TRPC1 channel.	PKD2 PKD2L1	1.36e-05	4	53	2	10097141
Pubmed	Evidence that C5b recognizes and mediates C8 incorporation into the cytolytic complex of complement.	C8A C9	1.36e-05	4	53	2	3624872
Pubmed	Functional cross-talk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4.	RAB4B RAB4A	1.36e-05	4	53	2	20534812
Pubmed	Murine mdr-1, mdr-2, and mdr-3 gene expression: no coinduction with the Cyp1a-1 and Nmo-1 genes in liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin.	ABCB1 ABCB4	1.36e-05	4	53	2	2069718
Pubmed	Functional studies of the MACPF domain of human complement protein C8alpha reveal sites for simultaneous binding of C8beta, C8gamma, and C9.	C8A C9	1.36e-05	4	53	2	16618117
Pubmed	Polycystin channels and kidney disease.	PKD2 PKD2L1	2.27e-05	5	53	2	11698076
Pubmed	The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues.	C8A C9	2.27e-05	5	53	2	10551839
Pubmed	Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells.	ABCB1 ABCB4	2.27e-05	5	53	2	15159385
Pubmed	Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.	PKD2 PKD2L1	2.27e-05	5	53	2	12809519
Pubmed	Genetic mapping of the mouse gene encoding dipeptidyl aminopeptidase-like proteins.	DPP6 ABCB1	2.27e-05	5	53	2	8499659
Pubmed	The Rab protein family: genetic mapping of six Rab genes in the mouse.	RAB4B RAB4A	3.40e-05	6	53	2	8825628
Pubmed	Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.	C8A C9	3.40e-05	6	53	2	22832194
Pubmed	High-resolution genetic map and YAC contig around the mouse neurological locus reeler.	DPP6 ABCB1	3.40e-05	6	53	2	7894155
Pubmed	Junctional Epidermolysis Bullosa	LAMA3 PLEC	3.40e-05	6	53	2	20301304
Pubmed	CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.	C8A C9	4.76e-05	7	53	2	30552328
Pubmed	Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.	LAMA3 PLEC	8.15e-05	9	53	2	12482924
Pubmed	Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.	PKD2 PKD2L1	1.02e-04	10	53	2	16805797
Pubmed	Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes.	ABCB1 ABCB4	1.02e-04	10	53	2	12068294
Pubmed	Localization of serine kinases, SRPK1 (SFRSK1) and SRPK2 (SFRSK2), specific for the SR family of splicing factors in mouse and human chromosomes.	DPP6 ABCB1	1.02e-04	10	53	2	10198174
Pubmed	Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1).	RAB4B RAB4A	1.02e-04	10	53	2	10329441
Pubmed	The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.	LAMA3 PLEC	1.24e-04	11	53	2	10811835
Pubmed	Current insights into the formation and breakdown of hemidesmosomes.	LAMA3 PLEC	1.24e-04	11	53	2	16757171
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	POLR3B TTC28 RSPH1 SEC23IP DNAAF9 EIF3D PLEC PLP1 ADD3	1.28e-04	1285	53	9	35914814
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	MGAM KRT24 LAMA3 C8A C9 SLC44A4 ABCB1 ABCB4	2.03e-04	1070	53	8	23533145
Pubmed	Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells.	ABCB1 ABCB4	2.70e-04	16	53	2	19794400
Pubmed	Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.	ABCB1 ABCB4	4.25e-04	20	53	2	21072184
Pubmed	Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.	RIN3 RAB4B PLEC KLHDC10 LANCL2	4.37e-04	418	53	5	32552912
Pubmed	A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.	DPP6 TTC28 USH2A	5.61e-04	105	53	3	23284306
Pubmed	An introduction to TRP channels.	PKD2 PKD2L1	7.80e-04	27	53	2	16460286
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	EDEM3 POLR3B TTC28 DNAJC16 SEC23IP CLUH	8.49e-04	733	53	6	34672954
Pubmed	Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.	C8A C9	1.10e-03	32	53	2	18842294
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	PKD2 PKD2L1	1.17e-03	33	53	2	19834762
Pubmed	Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma.	NEK2 C8A	1.24e-03	34	53	2	34050187
Pubmed	Human chromosome 7: DNA sequence and biology.	PDK4 KLHDC10 LANCL2 ABCB1 ABCB4	1.33e-03	536	53	5	12690205
Pubmed	Effects of glucokinase haploinsufficiency on the pancreatic β-cell mass and function of long-term high-fat, high-sucrose diet-fed mice.	DPP6 PDK4	1.47e-03	37	53	2	39305123
Cytoband	Ensembl 112 genes in cytogenetic band chr7q21	PDK4 ABCB1 ABCB4	1.16e-03	178	53	3	chr7q21
GeneFamily	ATP binding cassette subfamily B	ABCB1 ABCB4	2.22e-04	11	37	2	806
GeneFamily	Transient receptor potential cation channels	PKD2 PKD2L1	1.49e-03	28	37	2	249
GeneFamily	Complement system\|Sushi domain containing	C8A C9	2.46e-03	36	37	2	492
GeneFamily	Kelch like\|BTB domain containing	KLHL10 KLHL28	3.33e-03	42	37	2	617
GeneFamily	RAB, member RAS oncogene GTPases	RAB4B RAB4A	7.82e-03	65	37	2	388
GeneFamily	Solute carriers	SLC38A9 SLC26A5 SLC45A2 SLC44A4	8.39e-03	395	37	4	752
Coexpression	MITSIADES_RESPONSE_TO_APLIDIN_DN	EDEM3 CERK NEK2 PLEC RAB4A ADD3	1.12e-05	250	53	6	M11318
Coexpression	GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP	CERK TNFSF10 DNAJC16 PLEC CFAP46	5.12e-05	199	53	5	M3478
Coexpression	GSE4142_PLASMA_CELL_VS_GC_BCELL_UP	PDK4 GRIA1 DNAAF9 PLEC LANCL2	5.24e-05	200	53	5	M6390
Coexpression	GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_DN	CERK RIN3 PLEC ADD3 ABCB4	5.24e-05	200	53	5	M9735
Coexpression	GSE22432_CDC_VS_COMMON_DC_PROGENITOR_UP	CERK RIN3 RAB4B KLHL28 TXNDC16	5.24e-05	200	53	5	M7831
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KLHL10 RSPH1 SLC26A5 LAMA3 OTOG	2.08e-07	110	53	5	c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCell	facs-Heart-Unknown-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDK4 C8A C9 PLP1 ABCB1	1.22e-06	157	53	5	2ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDK4 C8A C9 PLP1 ABCB1	1.22e-06	157	53	5	8a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDK4 C8A C9 PLP1 ABCB1	1.22e-06	157	53	5	8d30d8e6fae93afcada6bd68799439335cd65b69
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEK2 RSPH1 SLC45A2 SLC44A4 CFAP46	2.13e-06	176	53	5	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	ASK452-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	RSPH1 IQCA1 PDK4 SLC44A4 CFAP46	3.35e-06	193	53	5	c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell	ASK452-Epithelial-Ciliated\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	RSPH1 IQCA1 PDK4 SLC44A4 CFAP46	3.43e-06	194	53	5	5aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC26A5 DHRS13 LAMA3 OTOG	8.40e-06	108	53	4	d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFSF10 FAT3 SLC44A4 PCSK4	1.69e-05	129	53	4	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-\|Striatum / BrainAtlas - Mouse McCarroll V32	PKD2L1 SLC45A2 C9	2.91e-05	50	53	3	5c06f52adbb2bbcf156f82e930948b10331ed730
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE-O1-Trf\|Striatum / BrainAtlas - Mouse McCarroll V32	PKD2L1 SLC45A2 C9	2.91e-05	50	53	3	1f1fee2a62d0665ac6ef8ece456c51e3cec3a6b6
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE-O1\|Striatum / BrainAtlas - Mouse McCarroll V32	PKD2L1 SLC45A2 C9	2.91e-05	50	53	3	041339abc4feded9a58b797204e04052e338c009
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)\|Striatum / BrainAtlas - Mouse McCarroll V32	PKD2L1 SLC45A2 C9	2.91e-05	50	53	3	301eaec701ee1f7ce825dfb905c37c7107e3dc88
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDK4 NNT RAB4A ABCB1	4.55e-05	166	53	4	94a00edf66d54bc5f7343daea700ca26cf38fd90
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN3 TNFSF10 TXNDC16 KLHDC10	5.96e-05	178	53	4	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEK2 RSPH1 PCSK4 CFAP46	6.23e-05	180	53	4	0c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEK2 RSPH1 PCSK4 CFAP46	6.23e-05	180	53	4	e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEK2 RSPH1 PCSK4 CFAP46	6.23e-05	180	53	4	11455ba704ac73f69b474845136cfecec6a88349
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 TNFSF10 PDK4 ADD3	6.36e-05	181	53	4	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH1 IQCA1 FAT3 SLC44A4	6.64e-05	183	53	4	2df1611c8acccb2a6f233d3d68bd9df2381a7278
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FAT3 USH2A OTOG	6.78e-05	184	53	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FAT3 USH2A OTOG	6.78e-05	184	53	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FAT3 USH2A OTOG	6.78e-05	184	53	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH1 IQCA1 FAT3 SLC44A4	6.78e-05	184	53	4	6388c47b7f1d8203e3069eba0e74107256dcae51
ToppCell	3'-Adult-SmallIntestine-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM PDK4 C8A ABCB1	6.78e-05	184	53	4	ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCell	droplet-Heart-4Chambers-18m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH1 IQCA1 FAT3 SLC44A4	6.78e-05	184	53	4	d83ae1dc64aa1b27d3b524c137567418cc0ff8c6
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH1 PKD2L1 SLC44A4 CFAP46	7.07e-05	186	53	4	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM PDK4 C8A ABCB1	7.07e-05	186	53	4	bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 IQCA1 SLC26A5 LAMA3	7.22e-05	187	53	4	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM PDK4 C8A ABCB1	7.22e-05	187	53	4	9042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTC28 IQCA1 TNFSF10 ABCB1	7.52e-05	189	53	4	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH1 IQCA1 SLC44A4 CFAP46	7.68e-05	190	53	4	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH1 IQCA1 SLC44A4 CFAP46	7.68e-05	190	53	4	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)\|356C / Donor, Lineage, Cell class and subclass (all cells)	RSPH1 IQCA1 SLC44A4 CFAP46	7.83e-05	191	53	4	e314dd8f1a841cab847ae3703bedfe1bc623ac61
ToppCell	ASK428-Epithelial-Ciliated\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	RSPH1 IQCA1 SLC44A4 CFAP46	7.83e-05	191	53	4	0c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	RSPH1 IQCA1 SLC44A4 CFAP46	7.83e-05	191	53	4	8a5a2188b13ef4bbfd626a42565566708a751c1b
ToppCell	LAM-Epithelial-AirwayEpi\|LAM / Condition, Lineage and Cell class	RSPH1 IQCA1 SLC44A4 CFAP46	7.99e-05	192	53	4	7404fc65be3b7bd09447725b43fa31819004dfee
ToppCell	Immune_cells-small_pre-B.\|Immune_cells / Lineage and Cell class	CERK NEK2 RSPH1 NNT	8.32e-05	194	53	4	6a440c09805110b1e48e5959a3a9e094c6716bfb
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQCA1 TNFSF10 SLC44A4 ABCB1	8.32e-05	194	53	4	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	RSPH1 IQCA1 SLC44A4 CFAP46	8.32e-05	194	53	4	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	DPP6 TTC28 FAT3 GRIA1	8.49e-05	195	53	4	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	RSPH1 IQCA1 SLC44A4 CFAP46	8.65e-05	196	53	4	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	RSPH1 IQCA1 SLC44A4 CFAP46	8.83e-05	197	53	4	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IQCA1 SLC26A5 LAMA3 SLC44A4	8.83e-05	197	53	4	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	distal-Epithelial-Ciliated-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RSPH1 IQCA1 SLC44A4 CFAP46	9.00e-05	198	53	4	d30d6c6a0a78b7571318b5b2a0186df96dd0f5a9
ToppCell	medial-Epithelial-Ciliated-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RSPH1 IQCA1 SLC44A4 CFAP46	9.18e-05	199	53	4	526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DPP6 IQCA1 SLC26A5 LAMA3	9.18e-05	199	53	4	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	distal-Epithelial-Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RSPH1 IQCA1 SLC44A4 CFAP46	9.18e-05	199	53	4	6ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCell	medial-Epithelial-Ciliated\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RSPH1 IQCA1 SLC44A4 CFAP46	9.18e-05	199	53	4	a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCell	distal-Epithelial-Ciliated\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RSPH1 IQCA1 SLC44A4 CFAP46	9.18e-05	199	53	4	18ca031cfe702afb9bf94e03c0f3680c38e7599e
ToppCell	distal-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RSPH1 IQCA1 SLC44A4 CFAP46	9.18e-05	199	53	4	97b66b82c76c7bc1fcd7da7b94dd2aa2d4d70a60
ToppCell	distal-1-Epithelial-Ciliated\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RSPH1 IQCA1 SLC44A4 CFAP46	9.18e-05	199	53	4	4120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCell	medial-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RSPH1 IQCA1 SLC44A4 CFAP46	9.18e-05	199	53	4	c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RSPH1 IQCA1 SLC44A4 CFAP46	9.36e-05	200	53	4	9c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EDEM3 LRP12 SLC26A5 SLC44A4	9.36e-05	200	53	4	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RSPH1 IQCA1 SLC44A4 CFAP46	9.36e-05	200	53	4	5abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CEACAM19 RSPH1 ASB14 SLC44A4	9.36e-05	200	53	4	4992dbf0514d674017315dbd20d91dfec0c608e9
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DPP6 IQCA1 SLC26A5 LAMA3	9.36e-05	200	53	4	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	severe_influenza-B_cell\|World / disease group, cell group and cell class (v2)	RAB4B ABCB1 ABCB4	1.47e-04	86	53	3	7b595bcba4bcb72b7de7c06e19f690f0c739c529
ToppCell	facs-MAT-Fat-3m-Epithelial-epithelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 PKD2L1 PLP1	1.86e-04	93	53	3	0d6d1d8dd9c91ba31eb35a4b5979d087890936c1
ToppCell	facs-MAT-Fat-3m-Epithelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 PKD2L1 PLP1	1.86e-04	93	53	3	abffb1fd5a919b7c08e62e1c3c08a8dd8783a4ca
ToppCell	facs-MAT-Fat-3m-Epithelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 PKD2L1 PLP1	1.86e-04	93	53	3	dbfaa7f23d25f5c286ab7ca3ca795b734cb95153
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE-O2-Tfr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PKD2L1 SLC45A2 PLP1	2.10e-04	97	53	3	4b74b3c5b9590a8215b7370b37e9723e9f040b9c
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE-O2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PKD2L1 SLC45A2 PLP1	2.10e-04	97	53	3	7b17dc28454949a23701ab127300a29a8899d7d6
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TNFSF10 LAMA3 SLC45A2	2.44e-04	102	53	3	2c3622fc3cd62d9b7e185d0204cf7f03e7dde73c
ToppCell	TCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Testicular_Germ_Cell_Tumor-2\|TCGA-Testes / Sample_Type by Project: Shred V9	KRT24 SLC45A2 C8A	3.13e-04	111	53	3	dbd6a30298c9f3b09b2b5ad93a14305e3438793d
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL10 DHRS13 ABCB1	4.54e-04	126	53	3	e33957cf1541733b06de9f9e7b2801b3d8ae831d
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	DPP6 FAT3 GRIA1	4.64e-04	127	53	3	5e4d110cc6e68cd8fc7a4771a65e6f8cd83e7721
ToppCell	severe_influenza-B_cell\|severe_influenza / disease group, cell group and cell class (v2)	RAB4B ABCB1 ABCB4	4.75e-04	128	53	3	92b250186d6bb08ce4f2f5cc4fb93928f6b92d3a
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CEACAM19 DPP6 LAMA3	4.97e-04	130	53	3	6434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell	facs-Heart-RV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHDC10 SLC44A4 PCSK4	5.55e-04	135	53	3	1fe684ed5913ae757ad6befbbe12d1bee481dd12
ToppCell	facs-Heart-RV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHDC10 SLC44A4 PCSK4	5.55e-04	135	53	3	99e7ac9b1139fe4ff036f6f048a8f1cc514c1fb9
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SLC45A2 USH2A	6.04e-04	139	53	3	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SLC45A2 USH2A	6.04e-04	139	53	3	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM PDK4 FAT3	6.29e-04	141	53	3	091b5b72811db5fca2314f4a79d467566920e257
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MGAM DNAAF9 CLUH	6.69e-04	144	53	3	5e948d4cb913ccd8f82262a1b4d20967aadab3ab
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC26A5 PKD2L1 USH2A	6.83e-04	145	53	3	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ABCG4 LANCL3 CFAP46	6.83e-04	145	53	3	8b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCell	E18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell\|E18.5-samps / Age Group, Lineage, Cell class and subclass	KLHL10 ASB14 SLC44A4	7.39e-04	149	53	3	82edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCell	E18.5-samps-Epithelial-Epithelial-non_alveolar\|E18.5-samps / Age Group, Lineage, Cell class and subclass	KLHL10 ASB14 SLC44A4	7.39e-04	149	53	3	14a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-4\|TCGA-Bladder / Sample_Type by Project: Shred V9	SLC26A5 PLP1 ABCB1	7.53e-04	150	53	3	bcb99c6fa81052556ab30f9db5875fccf1ae724b
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IQCA1 SLC26A5 ABCB1	8.13e-04	154	53	3	e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RSPH1 USH2A CFAP46	8.13e-04	154	53	3	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RSPH1 USH2A CFAP46	8.13e-04	154	53	3	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C8A C9 ABCB4	8.43e-04	156	53	3	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RSPH1 IQCA1 ABCB1	8.43e-04	156	53	3	bb2876bdf2375866d7509eba3c48322326349fa8
ToppCell	facs-Marrow-T-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT24 LAMA3 RAB4A	8.59e-04	157	53	3	ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC26A5 LAMA3	8.59e-04	157	53	3	9665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCell	facs-Marrow-T-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT24 LAMA3 RAB4A	8.59e-04	157	53	3	fddcb24776b9f86e000208bae54541b15b2adefd
ToppCell	facs-Heart-LV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM IQCA1 SLC45A2	8.75e-04	158	53	3	12a82230c01de552f12977634c304626e1cd6903
ToppCell	facs-Heart-LV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM IQCA1 SLC45A2	8.75e-04	158	53	3	bd432ecd2524656804e7c2775250e27db7906b70
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-9\|TCGA-Colorectal / Sample_Type by Project: Shred V9	DPP6 GRIA1 PLP1	8.91e-04	159	53	3	f376bf6cd0ed374211edac3c384f3a78f0caef2a
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LANCL3 GRIA1 SLC45A2	9.07e-04	160	53	3	dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RIN3 TNFSF10 SLC45A2	9.07e-04	160	53	3	04714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LANCL3 PCSK4 PLP1	9.07e-04	160	53	3	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC26A5 LAMA3	9.24e-04	161	53	3	1e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCell	Mild-MAIT\|Mild / Disease group and Cell class	CERK PDK4 ABCB1	9.24e-04	161	53	3	0c1a04485708d5302600cdc2d7dac1cb76b4033a
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LANCL3 IQCA1 FAT3	9.24e-04	161	53	3	f5df8c6a340d5026726804b103e32137f363ca40
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT3 PKD2L1 USH2A	9.41e-04	162	53	3	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	TCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	DPP6 FAT3 PLP1	9.41e-04	162	53	3	b115b5799137122bd60696f8ae2aebadad6cd044
Drug	avermectin	GRIA1 C8A ABCB1 ABCB4	4.72e-06	48	53	4	CID006450460
Drug	1,9-dideoxyforskolin	ABCB1 ABCB4	5.32e-06	2	53	2	ctd:C047983
Drug	magnesium	MGAM CERK POLR3B RAB4B PDK4 ENTPD6 LAMA3 GRIA1 PLEC NNT RAB4A ABCB1 ABCB4	7.83e-06	1325	53	13	CID000000888
Drug	Pgh1	MGAM ABCB1 ABCB4	7.91e-06	17	53	3	CID005283048
Drug	C19565	MGAM SLC45A2 PLEC	1.32e-05	20	53	3	CID000107819
Drug	AC1L3NFS	POLR3B LAMA3 SLC45A2	1.54e-05	21	53	3	CID000092111
Drug	DA-8159	SLC45A2 PLP1 ABCB1	1.54e-05	21	53	3	CID006918523
Drug	Technetium Tc 99m Sestamibi	ABCB1 ABCB4	1.59e-05	3	53	2	ctd:D017256
Drug	N(3)ATP	MGAM ABCB1	1.59e-05	3	53	2	CID000133414
Drug	pregnenolone-16 alpha-carbonitrile	SLC45A2 PLEC ABCB1 ABCB4	1.80e-05	67	53	4	CID000015032
Drug	dimethylaminobenzoate	ABCB1 ABCB4	3.18e-05	4	53	2	CID012241998
Drug	3 alpha,6 alpha-dihydroxy-5 beta-cholanoic acid	PLEC ABCB1 ABCB4	4.17e-05	29	53	3	CID000006747
Drug	rostafuroxin	ADD3 ABCB1	5.29e-05	5	53	2	ctd:C106263
Drug	AC1L2MCS	ABCB1 ABCB4	5.29e-05	5	53	2	CID000023441
Drug	pyropheophorbide-a methyl ester	MGAM ABCB1	7.93e-05	6	53	2	CID005476777
Drug	PIHCA	ABCB1 ABCB4	7.93e-05	6	53	2	CID000108097
Drug	v 104	ABCB1 ABCB4	7.93e-05	6	53	2	CID000107262
Drug	AC1L99H3	ABCB1 ABCB4	7.93e-05	6	53	2	CID000440540
Drug	AC1L3Z73	SLC45A2 ABCB1	7.93e-05	6	53	2	CID000097765
Drug	LY294002; Up 200; 10uM; SKMEL5; HG-U133A	ABCG4 EDEM3 PDK4 PLEC KLHDC10	8.57e-05	193	53	5	501_UP
Drug	MIANS	NNT ABCB1 ABCB4	8.75e-05	37	53	3	CID000119532
Drug	galangin	MGAM SLC45A2 ABCB1	8.75e-05	37	53	3	CID005281616
Drug	Dienestrol [84-17-3]; Down 200; 15uM; MCF7; HT_HG-U133A	EDEM3 CERK SEC23IP LAMA3 NNT	9.67e-05	198	53	5	6208_DN
Drug	Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; HL60; HG-U133A	ABCG4 MGAM RIN3 PLEC KLHDC10	9.90e-05	199	53	5	2012_UP
Drug	valinomycin	NNT ABCB1 ABCB4	1.03e-04	39	53	3	CID000005649
Drug	C12-NBD-PC	ABCB1 ABCB4	1.11e-04	7	53	2	CID006439314
Drug	N-dodecylimidazole	MGAM ABCB1	1.11e-04	7	53	2	CID000078002
Drug	racemethorphan	CERK GRIA1 SLC45A2 ABCB1	1.13e-04	107	53	4	CID000003008
Drug	perfluoro-n-nonanoic acid	PDK4 C9 ABCB1 ABCB4	1.44e-04	114	53	4	ctd:C101816
Drug	tBCEU	ABCB1 ABCB4	1.48e-04	8	53	2	CID000164059
Drug	tri-n-butylmethylammonium	ABCB1 ABCB4	1.48e-04	8	53	2	CID000036208
Drug	nicotine glucuronide	ABCB1 ABCB4	1.48e-04	8	53	2	CID003035848
Drug	iodoarylazidoprazosin	ABCB1 ABCB4	1.48e-04	8	53	2	CID000115344
Drug	T beta-MC	ABCB1 ABCB4	1.48e-04	8	53	2	CID000168408
Drug	thiopyrylium	ABCB1 ABCB4	1.48e-04	8	53	2	CID011344401
Drug	tXMP	ABCB1 ABCB4	1.48e-04	8	53	2	CID003081384
Drug	ciprofibrate	PDK4 C9 ABCB1 ABCB4	1.49e-04	115	53	4	ctd:C019304
Drug	AC1L1R04	SLC45A2 PLEC ABCB1	1.80e-04	47	53	3	CID000008439
Drug	GW3965	PLEC ABCB1 ABCB4	1.80e-04	47	53	3	CID000447905
Drug	AC1L8B0O	SLC45A2 ABCB1	1.89e-04	9	53	2	CID000324941
Drug	Ca 5	MGAM C9	1.89e-04	9	53	2	CID000090511
Drug	So324	ABCB1 ABCB4	1.89e-04	9	53	2	CID000462261
Drug	c219	ABCB1 ABCB4	1.89e-04	9	53	2	CID004198643
Drug	atorvastatin lactone	SLC45A2 ABCB1	1.89e-04	9	53	2	CID006483036
Disease	polycystic kidney disease 2 (implicated_via_orthology)	PKD2 PKD2L1	9.13e-06	3	52	2	DOID:0110859 (implicated_via_orthology)
Disease	colorectal adenocarcinoma (is_implicated_in)	RSPH1 PCSK4 ABCB1	3.25e-05	35	52	3	DOID:0050861 (is_implicated_in)
Disease	gallbladder neoplasm	ABCB1 ABCB4	1.09e-04	9	52	2	EFO_0004606
Disease	cystic fibrosis (implicated_via_orthology)	ABCB1 ABCB4	1.09e-04	9	52	2	DOID:1485 (implicated_via_orthology)
Disease	Alzheimer disease, dementia	POLR3B CFAP46	1.99e-04	12	52	2	MONDO_0001627, MONDO_0004975
Disease	Liver carcinoma	NEK2 TNFSF10 PDK4 C9 ABCB1 ABCB4	2.60e-04	507	52	6	C2239176
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	PKD2 PKD2L1	2.73e-04	14	52	2	DOID:898 (implicated_via_orthology)
Disease	hepatic encephalopathy (biomarker_via_orthology)	GRIA1 ABCB1	3.15e-04	15	52	2	DOID:13413 (biomarker_via_orthology)
Disease	Intrahepatic cholestasis of pregnancy	ABCB1 ABCB4	3.60e-04	16	52	2	EFO_0009048
Disease	Nonsyndromic Deafness	SLC26A5 SLC44A4 OTOG	4.00e-04	81	52	3	C3711374
Disease	Antibody Deficiency Syndrome	C8A C9	4.07e-04	17	52	2	C0003257
Disease	epilepsy (biomarker_via_orthology)	GRIA1 ABCB1	6.26e-04	21	52	2	DOID:1826 (biomarker_via_orthology)
Disease	Immunologic Deficiency Syndromes	C8A C9	7.53e-04	23	52	2	C0021051
Disease	aspartate aminotransferase to alanine aminotransferase ratio	PKD2L1 PLEC ABCB1 ABCB4	8.38e-04	239	52	4	EFO_0010934
Disease	apolipoprotein B measurement	CEACAM19 ENTPD6 PKD2L1 PLEC ABCB1 ABCB4	1.06e-03	663	52	6	EFO_0004615
Disease	forced expiratory volume, response to bronchodilator	DPP6 RIN3 RAB4B GRIA1 PLEC	1.11e-03	445	52	5	EFO_0004314, GO_0097366
Disease	Toxic Encephalitis	ADD3 ABCB1	1.20e-03	29	52	2	C0154659
Disease	Neurotoxicity Syndromes	ADD3 ABCB1	1.20e-03	29	52	2	C0235032
Disease	Encephalopathy, Toxic	ADD3 ABCB1	1.20e-03	29	52	2	C0149504
Disease	Complement deficiency disease	C8A C9	1.55e-03	33	52	2	C0272242

Protein segments in the cluster

Peptide	Gene	Start	Entry
SYLSYVRYGFEGVIL	ABCG4	566	Q9H172
YITSGSMGGIYEYIL	C8A	341	P07357
LLGDVAYYDYQGSLE	ADD3	256	Q9UEY8
AYYLEAYGLAQGAVA	CFAP46	1806	Q8IYW2
LYKEYDLYGQGIFTG	ASB14	571	A6NK59
LSDYIGEYSYLGTTL	IQCA1	516	Q86XH1
SYYRGAAGALLVYDI	RAB4A	81	P20338
SYYRGAAGALLVYDI	RAB4B	76	P61018
YYYSGIGAGVLVAAY	ABCB1	116	P08183
YSLSGYGTDAIIYLK	PDK4	351	Q16654
LDGTGYGDYVKIYDG	LRP12	306	Q9Y561
GDKVSSYGGYLTYQA	LAMA3	1526	Q16787
EDYEVLYTIGTGSYG	NEK2	6	P51955
GQSIDTYGKGLYYLA	MGAM	2651	O43451
SGVGAGIDSYYEYLL	EDEM3	286	Q9BZQ6
AGYLYALLYLNTEIG	LANCL2	201	Q9NS86
GTLYRYTLLLYGTAE	PCSK4	566	Q6UW60
NGSLYVFGGTTGYIY	KLHDC10	216	Q6PID8
DYLSFGYVYVGLRGT	DNAJC16	296	Q9Y2G8
GGSGRDYSKYYSIIE	KRT24	186	Q2M2I5
YYGTEYLGAAHGLSS	LANCL3	226	Q6ZV70
YAYYYSGLGAGVLVA	ABCB4	116	P21439
YLKGYVYIIGGFDSV	KLHL10	336	Q6JEL2
GELYALGGYDGQSYL	KLHL28	386	Q9NXS3
NYLYVVGGHSGSSYL	KLHL28	526	Q9NXS3
LRYSVSLLGYGFYGD	CERK	281	Q8TCT0
LAGSEYLKLGYVSRY	EIF3D	441	O15371
ADIGSNGYIRYSLYG	FAT3	3056	Q8TDW7
LGTYLTGGEGAYLYS	DNAAF9	536	Q5TEA3
YLGEETYGGTRLFTY	CEACAM19	66	Q7Z692
LILGVLGVLAYGIYY	SLC44A4	261	Q53GD3
VAVFGKDYGGYLSTY	DPP6	706	P42658
GYSYRLEIVSDGKYG	GRIA1	451	P42261
LVSYIGLKGLYFTGY	SLC45A2	391	Q9UMX9
LGSAYKLQSYTEGYG	SLC38A9	101	Q8NBW4
YSSSGSLGGLYELIY	C9	346	P02748
LGAGLLLGAYVLVYY	DHRS13	6	Q6UX07
GEGSYYLTTTYGALE	RIN3	821	Q8TB24
ETFDGLYYYLSGKGS	OTOG	161	Q6ZRI0
LYYYLSGKGSYTLVG	OTOG	166	Q6ZRI0
VGGYLAALYSGYNIE	NNT	606	Q13423
YPNGVITSYGLYLDG	USH2A	2266	O75445
AFSYYYDLAAGVGLI	ENTPD6	381	O75354
EYGDVGIYVYLAGCS	SLC26A5	666	P58743
GTYLYAETGSKYVGT	RSPH1	126	Q8WYR4
VLGTDGGRYDVYLYD	SEC23IP	311	Q9Y6Y8
GLYTLGTVVVDYRGY	CLUH	466	O75153
EAGNYLKGYVITGIY	TXNDC16	546	Q9P2K2
YNYLGKDYVTSGITG	POLR3B	981	Q9NW08
CYLYGTGSVAGVYLP	PLEC	3821	Q15149
GIIATYSGAGYYLDL	PKD2	381	Q13563
RLTSYSGGGYYLDLP	PKD2L1	261	Q9P0L9
GQRGLVLYYSLAAGY	TTC28	1231	Q96AY4
EYGLYSIYQGGIFEL	TNFSF10	236	P50591
LYGALLLAEGFYTTG	PLP1	81	P60201