Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	L-glutamate uniporter activity	SLC17A8 SLC17A6	1.11e-05	3	39	2	GO:0140788
GeneOntologyMolecularFunction	membrane potential driven uniporter activity	SLC17A8 SLC17A6	3.70e-05	5	39	2	GO:0022810
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS15 KEL ADAM15 TLL2	8.67e-05	120	39	4	GO:0004222
GeneOntologyMolecularFunction	uniporter activity	SLC17A8 SLC17A6	1.66e-04	10	39	2	GO:0015292
GeneOntologyMolecularFunction	growth factor binding	LTBP1 FGFR2 LTBP4 IL6R	2.38e-04	156	39	4	GO:0019838
GeneOntologyMolecularFunction	sodium:phosphate symporter activity	SLC17A8 SLC17A6	2.42e-04	12	39	2	GO:0005436
GeneOntologyMolecularFunction	transforming growth factor beta receptor activity	LTBP1 LTBP4	2.86e-04	13	39	2	GO:0005024
GeneOntologyMolecularFunction	L-glutamate transmembrane transporter activity	SLC17A8 SLC17A6	3.84e-04	15	39	2	GO:0005313
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	LTBP1 FGFR2 LTBP4	6.09e-04	85	39	3	GO:0019199
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS15 KEL ADAM15 TLL2	6.11e-04	200	39	4	GO:0008237
GeneOntologyMolecularFunction	transmembrane receptor protein serine/threonine kinase activity	LTBP1 LTBP4	6.91e-04	20	39	2	GO:0004675
GeneOntologyMolecularFunction	acidic amino acid transmembrane transporter activity	SLC17A8 SLC17A6	6.91e-04	20	39	2	GO:0015172
GeneOntologyMolecularFunction	neurotransmitter transmembrane transporter activity	SLC17A8 SLC17A6	7.62e-04	21	39	2	GO:0005326
GeneOntologyMolecularFunction	phosphate transmembrane transporter activity	SLC17A8 SLC17A6	9.98e-04	24	39	2	GO:0005315
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	ARHGEF25 MYCBP2 RALGPS1 VAV2	1.04e-03	231	39	4	GO:0005085
GeneOntologyMolecularFunction	transforming growth factor beta binding	LTBP1 LTBP4	1.17e-03	26	39	2	GO:0050431
GeneOntologyMolecularFunction	frizzled binding	WNT1 WNT9B	3.05e-03	42	39	2	GO:0005109
GeneOntologyMolecularFunction	structural constituent of skin epidermis	KRT4 KRT82	3.19e-03	43	39	2	GO:0030280
GeneOntologyMolecularFunction	cytokine binding	LTBP1 LTBP4 IL6R	3.54e-03	157	39	3	GO:0019955
GeneOntologyMolecularFunction	phosphotyrosine residue binding	IRS1 VAV2	4.46e-03	51	39	2	GO:0001784
GeneOntologyMolecularFunction	E-box binding	TCF3 ATOH1	6.33e-03	61	39	2	GO:0070888
GeneOntologyMolecularFunction	protein phosphorylated amino acid binding	IRS1 VAV2	8.03e-03	69	39	2	GO:0045309
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC17A8 SLC17A6	8.48e-03	71	39	2	GO:0015179
GeneOntologyMolecularFunction	extracellular matrix binding	ADAMTS15 LTBP1	8.95e-03	73	39	2	GO:0050840
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS15 KEL ADAM15 TLL2	9.62e-03	430	39	4	GO:0004175
GeneOntologyBiologicalProcess	cell fate commitment	TCF3 FGFR2 ATOH1 WNT1 IL6R WNT9B	3.29e-05	338	38	6	GO:0045165
GeneOntologyCellularComponent	pericellular basket	SLC17A8 SLC17A6	9.64e-06	3	38	2	GO:1990030
GeneOntologyCellularComponent	microfibril	LTBP1 LTBP4	2.48e-04	13	38	2	GO:0001527
GeneOntologyCellularComponent	cell surface	ADAMTS15 KRT4 TSPAN14 FGFR2 CUBN ADAM15 WNT1 IL6R	7.29e-04	1111	38	8	GO:0009986
GeneOntologyCellularComponent	intermediate filament	KRT4 KRTAP13-1 KRTAP13-2 KRT82	7.48e-04	227	38	4	GO:0005882
GeneOntologyCellularComponent	excitatory synapse	SLC17A8 FGFR2 SLC17A6	9.66e-04	107	38	3	GO:0060076
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRT4 KRTAP13-1 KRTAP13-2 KRT82	1.29e-03	263	38	4	GO:0045111
Domain	EGF_CA	LTBP1 CUBN LTBP4 TLL2	2.46e-05	86	37	4	PF07645
Domain	EGF_Ca-bd_CS	LTBP1 CUBN LTBP4 TLL2	3.96e-05	97	37	4	IPR018097
Domain	ZINC_PROTEASE	ADAMTS15 KEL ADAM15 TLL2	4.12e-05	98	37	4	PS00142
Domain	EGF_CA	LTBP1 CUBN LTBP4 TLL2	4.29e-05	99	37	4	PS01187
Domain	EGF-type_Asp/Asn_hydroxyl_site	LTBP1 CUBN LTBP4 TLL2	5.60e-05	106	37	4	IPR000152
Domain	TB	LTBP1 LTBP4	7.97e-05	7	37	2	PF00683
Domain	EGF_3	LTBP1 CUBN LTBP4 ADAM15 TLL2	9.48e-05	235	37	5	PS50026
Domain	EGF	LTBP1 CUBN LTBP4 ADAM15 TLL2	9.48e-05	235	37	5	SM00181
Domain	EGF_CA	LTBP1 CUBN LTBP4 TLL2	9.69e-05	122	37	4	SM00179
Domain	EGF-like_Ca-bd_dom	LTBP1 CUBN LTBP4 TLL2	1.03e-04	124	37	4	IPR001881
Domain	-	LTBP1 LTBP4	1.06e-04	8	37	2	3.90.290.10
Domain	EGF-like_dom	LTBP1 CUBN LTBP4 ADAM15 TLL2	1.24e-04	249	37	5	IPR000742
Domain	TB	LTBP1 LTBP4	1.36e-04	9	37	2	PS51364
Domain	TB_dom	LTBP1 LTBP4	1.36e-04	9	37	2	IPR017878
Domain	EGF_1	LTBP1 CUBN LTBP4 ADAM15 TLL2	1.39e-04	255	37	5	PS00022
Domain	EGF-like_CS	LTBP1 CUBN LTBP4 ADAM15 TLL2	1.55e-04	261	37	5	IPR013032
Domain	EGF_2	LTBP1 CUBN LTBP4 ADAM15 TLL2	1.66e-04	265	37	5	PS01186
Domain	PMG	KRTAP13-1 KRTAP13-2	2.94e-04	13	37	2	PF05287
Domain	KRTAP_PMG	KRTAP13-1 KRTAP13-2	2.94e-04	13	37	2	IPR007951
Domain	MetalloPept_cat_dom	ADAMTS15 ADAM15 TLL2	5.49e-04	81	37	3	IPR024079
Domain	-	ADAMTS15 ADAM15 TLL2	5.49e-04	81	37	3	3.40.390.10
Domain	Wnt	WNT1 WNT9B	6.39e-04	19	37	2	IPR005817
Domain	WNT1	WNT1 WNT9B	6.39e-04	19	37	2	SM00097
Domain	Wnt_CS	WNT1 WNT9B	6.39e-04	19	37	2	IPR018161
Domain	wnt	WNT1 WNT9B	6.39e-04	19	37	2	PF00110
Domain	WNT1	WNT1 WNT9B	6.39e-04	19	37	2	PS00246
Domain	ASX_HYDROXYL	LTBP1 CUBN LTBP4	1.01e-03	100	37	3	PS00010
Domain	Ig_E-set	MYCBP2 NFATC4 EBF4	1.14e-03	104	37	3	IPR014756
Domain	Keratin_II	KRT4 KRT82	1.20e-03	26	37	2	IPR003054
Domain	ADAM_Cys-rich	ADAMTS15 ADAM15	1.30e-03	27	37	2	IPR006586
Domain	IPT	NFATC4 EBF4	1.30e-03	27	37	2	SM00429
Domain	ACR	ADAMTS15 ADAM15	1.30e-03	27	37	2	SM00608
Domain	HLH	TCF3 ATOH1 EBF4	1.56e-03	116	37	3	SM00353
Domain	TIG	NFATC4 EBF4	1.71e-03	31	37	2	PF01833
Domain	IPT	NFATC4 EBF4	1.82e-03	32	37	2	IPR002909
Domain	EGF	LTBP1 CUBN TLL2	1.97e-03	126	37	3	PF00008
Domain	PH	IRS1 ARHGEF25 RALGPS1 VAV2	2.16e-03	278	37	4	SM00233
Domain	PH_DOMAIN	IRS1 ARHGEF25 RALGPS1 VAV2	2.18e-03	279	37	4	PS50003
Domain	PH_domain	IRS1 ARHGEF25 RALGPS1 VAV2	2.21e-03	280	37	4	IPR001849
Domain	Peptidase_M12B_N	ADAMTS15 ADAM15	2.70e-03	39	37	2	IPR002870
Domain	Pep_M12B_propep	ADAMTS15 ADAM15	2.70e-03	39	37	2	PF01562
Domain	DISINTEGRIN_1	ADAMTS15 ADAM15	2.84e-03	40	37	2	PS00427
Domain	ADAM_MEPRO	ADAMTS15 ADAM15	2.84e-03	40	37	2	PS50215
Domain	DISINTEGRIN_2	ADAMTS15 ADAM15	2.84e-03	40	37	2	PS50214
Domain	Reprolysin	ADAMTS15 ADAM15	2.84e-03	40	37	2	PF01421
Domain	Peptidase_M12B	ADAMTS15 ADAM15	2.84e-03	40	37	2	IPR001590
Domain	CYSTEINE_SWITCH	ADAMTS15 ADAM15	2.98e-03	41	37	2	PS00546
Domain	Disintegrin_dom	ADAMTS15 ADAM15	2.98e-03	41	37	2	IPR001762
Domain	Pept_M10_metallopeptidase	ADAMTS15 ADAM15	3.28e-03	43	37	2	IPR001818
Domain	Keratin_I	KRT4 KRT82	3.43e-03	44	37	2	IPR002957
Domain	Growth_fac_rcpt_	LTBP1 CUBN LTBP4	3.61e-03	156	37	3	IPR009030
Domain	CUB	CUBN TLL2	4.24e-03	49	37	2	PF00431
Domain	CUB	CUBN TLL2	4.41e-03	50	37	2	SM00042
Domain	-	CUBN TLL2	4.76e-03	52	37	2	2.60.120.290
Domain	CUB	CUBN TLL2	4.94e-03	53	37	2	PS01180
Domain	CUB_dom	CUBN TLL2	5.69e-03	57	37	2	IPR000859
Domain	Intermediate_filament_CS	KRT4 KRT82	6.91e-03	63	37	2	IPR018039
Domain	DH_1	ARHGEF25 VAV2	6.91e-03	63	37	2	PS00741
Domain	-	IRS1 ARHGEF25 RALGPS1 VAV2	7.24e-03	391	37	4	2.30.29.30
Domain	RhoGEF	ARHGEF25 VAV2	8.01e-03	68	37	2	SM00325
Domain	DH_2	ARHGEF25 VAV2	8.47e-03	70	37	2	PS50010
Domain	RhoGEF	ARHGEF25 VAV2	8.47e-03	70	37	2	PF00621
Domain	DH-domain	ARHGEF25 VAV2	8.71e-03	71	37	2	IPR000219
Domain	-	ARHGEF25 VAV2	8.71e-03	71	37	2	1.20.900.10
Domain	IF	KRT4 KRT82	8.95e-03	72	37	2	PS00226
Domain	Filament	KRT4 KRT82	9.19e-03	73	37	2	PF00038
Domain	-	FGFR2 MYCBP2 NFATC4 IL6R EBF4	9.45e-03	663	37	5	2.60.40.10
Domain	PH_dom-like	IRS1 ARHGEF25 RALGPS1 VAV2	9.73e-03	426	37	4	IPR011993
Pubmed	Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6.	FGFR2 ATOH1 WNT1	4.70e-07	14	39	3	16364898
Pubmed	Auditory Neural Activity in Congenitally Deaf Mice Induced by Infrared Neural Stimulation.	SLC17A8 ATOH1	1.23e-06	2	39	2	29321651
Pubmed	Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells.	SLC17A8 SLC17A6	1.23e-06	2	39	2	28559797
Pubmed	A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.	FGFR2 ATOH1 WNT1	1.47e-06	20	39	3	18536717
Pubmed	Enhancer viruses for combinatorial cell-subclass-specific labeling.	SLC17A8 VIPR2 SLC17A6	1.47e-06	20	39	3	33789083
Pubmed	A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality.	SLC17A8 VIPR2 SLC17A6	1.71e-06	21	39	3	30007418
Pubmed	Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.	ATOH1 WNT1 SLC17A6	2.60e-06	24	39	3	24335253
Pubmed	Glutamatergic cerebellar neurons differentially contribute to the acquisition of motor and social behaviors.	ATOH1 SLC17A6	3.67e-06	3	39	2	37188723
Pubmed	Median raphe controls acquisition of negative experience in the mouse.	SLC17A8 SLC17A6	3.67e-06	3	39	2	31780530
Pubmed	Homeostatic regulation of excitatory synapses on striatal medium spiny neurons expressing the D2 dopamine receptor.	SLC17A8 SLC17A6	3.67e-06	3	39	2	25782435
Pubmed	Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.	SLC17A8 SLC17A6	3.67e-06	3	39	2	23467360
Pubmed	Wnt1 expression temporally allocates upper rhombic lip progenitors and defines their terminal cell fate in the cerebellum.	ATOH1 WNT1	3.67e-06	3	39	2	22173107
Pubmed	Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.	SLC17A8 SLC17A6	3.67e-06	3	39	2	33440152
Pubmed	Docking and homology modeling explain inhibition of the human vesicular glutamate transporters.	SLC17A8 SLC17A6	3.67e-06	3	39	2	17660252
Pubmed	Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1.	SLC17A8 ATOH1 SLC17A6	3.74e-06	27	39	3	20080794
Pubmed	Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization.	SLC17A8 VIPR2 SLC17A6	6.32e-06	32	39	3	34387544
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	LTBP1 LTBP4	7.34e-06	4	39	2	12429738
Pubmed	Glutamate inputs send prediction error of reward, but not negative value of aversive stimuli, to dopamine neurons.	SLC17A8 SLC17A6	7.34e-06	4	39	2	38278147
Pubmed	Atoh1-dependent rhombic lip neurons are required for temporal delay between independent respiratory oscillators in embryonic mice.	ATOH1 SLC17A6	7.34e-06	4	39	2	24842997
Pubmed	Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.	LTBP1 LTBP4	7.34e-06	4	39	2	15611103
Pubmed	Shared and distinct transcriptomic cell types across neocortical areas.	SLC17A8 VIPR2	7.34e-06	4	39	2	30382198
Pubmed	Mammalian tolloid proteinases: role in growth factor signalling.	LTBP1 TLL2	7.34e-06	4	39	2	27391803
Pubmed	The latent transforming growth factor beta binding protein (LTBP) family.	LTBP1 LTBP4	7.34e-06	4	39	2	11104663
Pubmed	Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.	LTBP1 LTBP4	7.34e-06	4	39	2	16157329
Pubmed	A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation.	SLC17A8 VIPR2 SLC17A6	7.62e-06	34	39	3	34004146
Pubmed	Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.	CUBN WNT1 WNT9B	9.07e-06	36	39	3	33737325
Pubmed	Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain.	FGFR2 ATOH1 WNT1	9.07e-06	36	39	3	22278924
Pubmed	A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.	HOXB6 TCF3 ATOH1 CUBN	9.45e-06	118	39	4	16971476
Pubmed	Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head.	FGFR2 CUBN WNT1	9.86e-06	37	39	3	23592779
Pubmed	Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm.	LTBP1 LTBP4	1.22e-05	5	39	2	19897194
Pubmed	Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy.	SLC17A8 SLC17A6	1.22e-05	5	39	2	36595933
Pubmed	Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis.	ATOH1 WNT1	1.22e-05	5	39	2	8872459
Pubmed	Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling.	SLC17A8 SLC17A6	1.83e-05	6	39	2	28957668
Pubmed	Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.	LTBP1 LTBP4	1.83e-05	6	39	2	19349279
Pubmed	Mammalian Merkel cells are descended from the epidermal lineage.	ATOH1 SLC17A6	1.83e-05	6	39	2	19782676
Pubmed	Sensory representation and detection mechanisms of gut osmolality change.	VIPR2 SLC17A6	1.83e-05	6	39	2	35082448
Pubmed	The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors.	TCF3 ATOH1	1.83e-05	6	39	2	17878293
Pubmed	Dorsal Horn Circuits for Persistent Mechanical Pain.	SLC17A8 SLC17A6	1.83e-05	6	39	2	26291162
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	FGFR2 WNT1 WNT9B	2.04e-05	47	39	3	33141892
Pubmed	The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas.	SLC17A8 VIPR2 SLC17A6	2.18e-05	48	39	3	32386544
Pubmed	Regional and cell-type-specific afferent and efferent projections of the mouse claustrum.	SLC17A8 VIPR2 SLC17A6	2.46e-05	50	39	3	36774552
Pubmed	Independently specified Atoh1 domains define novel developmental compartments in rhombomere 1.	FGFR2 ATOH1	2.56e-05	7	39	2	24381197
Pubmed	Three types of neurochemical projection from the bed nucleus of the stria terminalis to the ventral tegmental area in adult mice.	SLC17A8 SLC17A6	2.56e-05	7	39	2	23238719
Pubmed	PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.	SLC17A8 ATOH1	2.56e-05	7	39	2	34244441
Pubmed	Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts.	TCF3 NFATC4	2.56e-05	7	39	2	17430895
Pubmed	Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression.	LTBP1 LTBP4	2.56e-05	7	39	2	19998449
Pubmed	Merkel cells are essential for light-touch responses.	ATOH1 SLC17A6	2.56e-05	7	39	2	19541997
Pubmed	Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.	LTBP1 LTBP4	2.56e-05	7	39	2	10930463
Pubmed	[A study of the single nucleotide polymorphism in seven genes (GHR, IGFBP3, IGFR1, IRS1, FMN1, ANXA2, TaGLN) in ethnic Russians and in patients with prostate cancer].	IRS1 SLC17A6	2.56e-05	7	39	2	20540360
Pubmed	Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules.	TCF3 IL6R	2.56e-05	7	39	2	25009770
Pubmed	Expression patterns of FGF receptors in the developing mammalian cochlea.	FGFR2 ATOH1	2.56e-05	7	39	2	20131355
Pubmed	Dissection of Merkel cell formation in hairy and glabrous skin reveals a common requirement for FGFR2-mediated signalling.	FGFR2 ATOH1	2.56e-05	7	39	2	30758073
Pubmed	Specific connections of the interpeduncular subnuclei reveal distinct components of the habenulopeduncular pathway.	SLC17A8 SLC17A6	2.56e-05	7	39	2	28387937
Pubmed	Endothelial Cyp26b1 restrains murine heart valve growth during development.	FGFR2 NFATC4 ADAM15 WNT9B	3.37e-05	163	39	4	35364055
Pubmed	The Transcription Factor Pou3f1 Sheds Light on the Development and Molecular Diversity of Glutamatergic Cerebellar Nuclear Neurons in the Mouse.	ATOH1 SLC17A6	3.42e-05	8	39	2	35935334
Pubmed	Piezo2 is required for Merkel-cell mechanotransduction.	ATOH1 SLC17A6	3.42e-05	8	39	2	24717433
Pubmed	Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.	LTBP1 LTBP4	3.42e-05	8	39	2	27339457
Pubmed	Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditory nuclei.	ATOH1 SLC17A6	3.42e-05	8	39	2	19741118
Pubmed	Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1.	ATOH1 SLC17A6	4.39e-05	9	39	2	28297715
Pubmed	The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO₂.	ATOH1 SLC17A6	4.39e-05	9	39	2	25866925
Pubmed	Respiratory Network Stability and Modulatory Response to Substance P Require Nalcn.	ATOH1 SLC17A6	4.39e-05	9	39	2	28392070
Pubmed	Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors.	TCF3 ATOH1	4.39e-05	9	39	2	8948587
Pubmed	Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth.	ATOH1 WNT1	4.39e-05	9	39	2	19741143
Pubmed	Enteroendocrine cell types that drive food reward and aversion.	SLC17A8 SLC17A6	4.39e-05	9	39	2	35913117
Pubmed	Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.	IRS1 IL6R	5.48e-05	10	39	2	19124510
Pubmed	The isthmic neuroepithelium is essential for cerebellar midline fusion.	ATOH1 WNT1	5.48e-05	10	39	2	14507778
Pubmed	Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons.	ATOH1 SLC17A6	5.48e-05	10	39	2	19940179
Pubmed	Roof plate and dorsal spinal cord dl1 interneuron development in the dreher mutant mouse.	ATOH1 WNT1	5.48e-05	10	39	2	15183721
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	IRS1 LTBP1 FGFR2 WNT1 IL6R	6.68e-05	383	39	5	19453261
Pubmed	The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons.	ATOH1 SLC17A6	6.70e-05	11	39	2	21307253
Pubmed	Fgf20 is required for sensory epithelial specification in the developing cochlea.	FGFR2 ATOH1	6.70e-05	11	39	2	18524904
Pubmed	Math1 is essential for the development of hindbrain neurons critical for perinatal breathing.	ATOH1 SLC17A6	6.70e-05	11	39	2	19914183
Pubmed	Bone morphogenetic protein signaling is required in the dorsal neural folds before neurulation for the induction of spinal neural crest cells and dorsal neurons.	ATOH1 WNT1	6.70e-05	11	39	2	21394823
Pubmed	Mitochondrial retention of Opa1 is required for mouse embryogenesis.	HOXB6 WNT1	6.70e-05	11	39	2	20652258
Pubmed	Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development.	SLC17A8 ATOH1	6.70e-05	11	39	2	35925886
Pubmed	Atoh1 drives the heterogeneity of the pontine nuclei neurons and promotes their differentiation.	ATOH1 SLC17A6	6.70e-05	11	39	2	37390208
Pubmed	Wnt produced by stretched roof-plate cells is required for the promotion of cell proliferation around the central canal of the spinal cord.	ATOH1 WNT1	6.70e-05	11	39	2	30651295
Pubmed	Teashirt 3 regulates development of neurons involved in both respiratory rhythm and airflow control.	ATOH1 SLC17A6	6.70e-05	11	39	2	20631175
Pubmed	Lim 1 is required for nephric duct extension and ureteric bud morphogenesis.	FGFR2 WNT9B	6.70e-05	11	39	2	16216236
Pubmed	Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord.	ATOH1 WNT1	8.03e-05	12	39	2	9808626
Pubmed	Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation.	ATOH1 WNT1	8.03e-05	12	39	2	17151198
Pubmed	Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development.	SLC17A8 ATOH1	8.03e-05	12	39	2	37171961
Pubmed	Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures.	FGFR2 WNT1	8.03e-05	12	39	2	10751172
Pubmed	Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding.	ATOH1 WNT1	8.03e-05	12	39	2	10952903
Pubmed	LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons.	TCF3 SLC17A6	8.03e-05	12	39	2	19323994
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	TCF3 ATOH1 MYCBP2	8.66e-05	76	39	3	27542412
Pubmed	Enforced expression of the transcription factor HOXD3 under the control of the Wnt1 regulatory element modulates cell adhesion properties in the developing mouse neural tube.	ATOH1 WNT1	9.48e-05	13	39	2	21929743
Pubmed	Analysis of Cdh22 expression and function in the developing mouse brain.	WNT1 SLC17A6	9.48e-05	13	39	2	21761482
Pubmed	LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia.	FGFR2 WNT9B	9.48e-05	13	39	2	26047795
Pubmed	A medullary centre for lapping in mice.	ATOH1 SLC17A6	9.48e-05	13	39	2	34728601
Pubmed	Wnt signalling required for expansion of neural crest and CNS progenitors.	ATOH1 WNT1	9.48e-05	13	39	2	9353119
Pubmed	Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord.	ATOH1 WNT1	9.48e-05	13	39	2	11877374
Pubmed	Molecular characterization of the mouse superior lateral parabrachial nucleus through expression of the transcription factor Runx1.	ATOH1 SLC17A6	1.11e-04	14	39	2	21085653
Pubmed	Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice.	HOXB6 WNT9B	1.11e-04	14	39	2	12753872
Pubmed	Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.	TCF3 ATOH1	1.11e-04	14	39	2	14757642
Pubmed	Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling.	LTBP1 LTBP4	1.27e-04	15	39	2	17804598
Pubmed	A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development.	ATOH1 WNT1	1.27e-04	15	39	2	27414798
Pubmed	EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development.	SLC17A8 ATOH1	1.27e-04	15	39	2	38176908
Pubmed	Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.	KRT4 KRT82	1.46e-04	16	39	2	12399393
Pubmed	HESX1- and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain.	TCF3 WNT1	1.46e-04	16	39	2	22007134
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	KRT4 ARHGEF25 WNT1 KRT82	4.53e-04	423	39	4	chr12q13
Cytoband	21q22.1	KRTAP13-1 KRTAP13-2	5.11e-04	39	39	2	21q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11p14	CCDC34 SLC17A6	1.21e-03	60	39	2	chr11p14
Cytoband	12q13	WNT1 KRT82	1.68e-03	71	39	2	12q13
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP1 LTBP4	1.59e-05	4	30	2	628
GeneFamily	Wnt family\|Endogenous ligands	WNT1 WNT9B	4.47e-04	19	30	2	360
GeneFamily	Keratins, type II	KRT4 KRT82	9.10e-04	27	30	2	609
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	IRS1 RALGPS1 VAV2	4.72e-03	206	30	3	682
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF25 VAV2	5.34e-03	66	30	2	722
GeneFamily	Keratin associated proteins	KRTAP13-1 KRTAP13-2	1.40e-02	109	30	2	619
GeneFamily	Basic helix-loop-helix proteins	TCF3 ATOH1	1.43e-02	110	30	2	420
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LTBP1 LTBP4 ADAM15 WNT9B	1.18e-05	161	39	4	f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSPAN14 LTBP1 ADAM15 WNT9B	1.64e-05	175	39	4	2e54961846c65b185d9bd6e305dd81205579d890
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSPAN14 LTBP1 ADAM15 WNT9B	1.64e-05	175	39	4	efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCell	NS-critical-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDCA5 ADAM15 CCDC34 EBF4	1.67e-05	176	39	4	7cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IRS1 LTBP1 NFATC4 EBF4	1.71e-05	177	39	4	e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell	Pericytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS15 VIPR2 LTBP1 ARHGEF25	1.87e-05	181	39	4	ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 LTBP1 ARHGEF25 LTBP4	1.87e-05	181	39	4	6d1f1ad35778a2a227f966f11f6edd8e89452576
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	LTBP1 LTBP4 ADAM15 WNT9B	1.99e-05	184	39	4	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FGFR2 CUBN EBF4 FAM149A	2.12e-05	187	39	4	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 VIPR2 LTBP1 LTBP4	2.26e-05	190	39	4	00fd993675faf53adf985b9316a18c8a33242029
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LTBP1 LTBP4 ADAM15 WNT9B	2.26e-05	190	39	4	e1b721bb74561fe51c53328a0394c9954e489049
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LTBP1 LTBP4 ADAM15 WNT9B	2.26e-05	190	39	4	9b0ad888eb20acc011904d8593bc32bdef18d050
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 VIPR2 LTBP1 LTBP4	2.26e-05	190	39	4	8cda09d761c6b504a744959d587c183f94f1beeb
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VIPR2 IRS1 ARHGEF25 LTBP4	2.30e-05	191	39	4	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS15 VIPR2 LTBP1 LTBP4	2.30e-05	191	39	4	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS15 LTBP1 ARHGEF25 LTBP4	2.30e-05	191	39	4	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIPR2 LTBP1 ARHGEF25 NFATC4	2.30e-05	191	39	4	8597a8af294f24496c317d995f07eb5dcc25c13c
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS15 LTBP1 ARHGEF25 LTBP4	2.30e-05	191	39	4	de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS15 LTBP1 ARHGEF25 LTBP4	2.30e-05	191	39	4	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS15 VIPR2 LTBP1 LTBP4	2.30e-05	191	39	4	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	droplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 VIPR2 LTBP1 LTBP4	2.35e-05	192	39	4	c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
ToppCell	droplet-Lung-1m-Mesenchymal\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS15 LTBP1 ARHGEF25 LTBP4	2.35e-05	192	39	4	01433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VIPR2 CDCA5 CCDC34 SLC17A6	2.35e-05	192	39	4	f518839ecd9377537a414e8798766f7d91eafeac
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 VIPR2 LTBP1 LTBP4	2.35e-05	192	39	4	d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VIPR2 IRS1 ARHGEF25 LTBP4	2.35e-05	192	39	4	992d08092edbc68c47b945deb8708379738c239a
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LTBP1 LTBP4 ADAM15 WNT9B	2.35e-05	192	39	4	c157981b9a179925edcaabc0cb3b8805f0929004
ToppCell	droplet-Lung-nan-21m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 VIPR2 HOXB6 LTBP4	2.35e-05	192	39	4	e429e8fbc48ad26204a0197b9129e58be56bd7b6
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LTBP1 LTBP4 ADAM15 WNT9B	2.35e-05	192	39	4	cd4c9b9ab17a779c154264f7459020f51e528ba5
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXB6 FGFR2 CUBN LTBP4	2.40e-05	193	39	4	2b80991e7ba7640f7ab2139d30e4c54d8e533862
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-myofibroblast_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXB6 FGFR2 CUBN LTBP4	2.40e-05	193	39	4	90cfc34c2d0d7c70f071703d35db1d6037961481
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS15 LTBP1 LTBP4 VAV2	2.40e-05	193	39	4	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CHSY3 LTBP1 NFATC4 LTBP4	2.60e-05	197	39	4	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CHSY3 LTBP1 NFATC4 LTBP4	2.60e-05	197	39	4	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	erythropoietic-Basophilic_Erythroblast\|World / Lineage and Cell class	KEL LTBP1 CDCA5 CCDC34	2.65e-05	198	39	4	b3db4db02c0e659163cefb3d83f53e4940cc04bf
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IRS1 LTBP1 ARHGEF25 LTBP4	2.71e-05	199	39	4	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ADAMTS15 LTBP1 MYCBP2 LTBP4	2.71e-05	199	39	4	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	IRS1 LTBP1 ARHGEF25 LTBP4	2.76e-05	200	39	4	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	IRS1 LTBP1 ARHGEF25 LTBP4	2.76e-05	200	39	4	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	IRS1 LTBP1 ARHGEF25 LTBP4	2.76e-05	200	39	4	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	ADAMTS15 LTBP1 MYCBP2 LTBP4	2.76e-05	200	39	4	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	IRS1 LTBP1 ARHGEF25 LTBP4	2.76e-05	200	39	4	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	IRS1 LTBP1 ARHGEF25 LTBP4	2.76e-05	200	39	4	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	VIPR2 IRS1 LTBP1 LTBP4	2.76e-05	200	39	4	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CHSY3 LTBP1 ARHGEF25 VAV2	2.76e-05	200	39	4	a372ef3f9e6ff6e3c3376d6e10182977c5067788
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IRS1 LTBP1 ARHGEF25 LTBP4	2.76e-05	200	39	4	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHSY3 IRS1 LTBP1 NFATC4	2.76e-05	200	39	4	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Adcyap1_(Dentate_hilum?)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KEL CUBN WNT9B	2.78e-05	67	39	3	52f6c244e8d89ccacb79bc5ef3663a5d01fd393c
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Adcyap1_(Dentate_hilum?)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KEL CUBN WNT9B	2.78e-05	67	39	3	e462f9b5dca7c64101a31891f25654c05f2d215d
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cacng4_(Non-anterior_nuclei)\|Thalamus / BrainAtlas - Mouse McCarroll V32	VIPR2 HOXB6 WNT9B	4.05e-05	76	39	3	4afc8d0e79870c635a89dd8e7ca91ebfe482b4ab
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS15 VIPR2 TRIM17	4.55e-05	79	39	3	cc17a013a4a57a99c404b10449ef61ce559631d1
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS15 VIPR2 TRIM17	4.55e-05	79	39	3	19fb2bc964589ea40e7b9f0809c641331c93dacd
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KEL CUBN WNT9B	4.55e-05	79	39	3	03c5af851b53800eced1c74e9da374c71092bcd4
ToppCell	Thalamus\|World / BrainAtlas - Mouse McCarroll V32	VIPR2 WNT9B SLC17A6	1.43e-04	116	39	3	5ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell	Severe-B_naive-9\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HOXB6 KEL RFX6	1.46e-04	117	39	3	b5c27f24272216fa9f9107f5d00f3077847bb7ed
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KRT4 CHSY3 FGFR2	2.04e-04	131	39	3	9ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCell	Severe-B_naive-9\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HOXB6 KEL RFX6	2.43e-04	139	39	3	b9b049953958f15d773eb5cca6d5dc34f4829543
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRS1 LTBP4 WNT1	2.48e-04	140	39	3	e442c46979d725ec82f525a001c46d971fcade4d
ToppCell	IIH-CD4-CD8_1\|IIH / Condition, Cell_class and T cell subcluster	VIPR2 FGFR2 TRIM17	2.75e-04	145	39	3	296b6b0eea3233d76742ea35252b2f54d4c27ab6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 LTBP1 ARHGEF25	3.16e-04	152	39	3	0cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 LTBP1 ARHGEF25	3.16e-04	152	39	3	ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCell	Club_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	KRT4 TRIM17 EBF4	3.22e-04	153	39	3	77030b0e033f3635b1bbe7552a28c074ea7bb106
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LTBP1 NFATC4 CDCA5	3.35e-04	155	39	3	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	Paneth_cell\|World / shred on cell type and cluster	NOXO1 ATOH1 TRIM17	3.67e-04	160	39	3	d787b7cdb8c3f677ac9c4934a5df9cc194df3987
ToppCell	C_07\|World / shred on cell type and cluster	NOXO1 ATOH1 TRIM17	3.67e-04	160	39	3	b7c5a8a1c85da92e1945721b6887b32fad7b76b8
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	VIPR2 LTBP1 ARHGEF25	3.74e-04	161	39	3	64891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF3 NFATC4 VAV2	3.74e-04	161	39	3	63f0b97c741b610c450f65fa5764d712bfe09ce8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 DRICH1 ARHGEF25	3.81e-04	162	39	3	68c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 DRICH1 ARHGEF25	3.81e-04	162	39	3	735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 LTBP1 ARHGEF25	4.02e-04	165	39	3	9de841c1c95967c562720feba930246debc626fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 LTBP1 ARHGEF25	4.02e-04	165	39	3	a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 LTBP1 ARHGEF25	4.02e-04	165	39	3	cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-6\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	KRT4 KRTAP13-1 KRTAP13-2	4.16e-04	167	39	3	4a533972a0f40fff82dccf8e64716cb34f75736e
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ARHGEF25 NFATC4 EBF4	4.16e-04	167	39	3	5c82d801e3b7d7c6c967a73b94b2ee2a8da1fd6e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHSY3 LTBP1 NFATC4	4.23e-04	168	39	3	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LTBP1 LTBP4 ADAM15	4.31e-04	169	39	3	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 LTBP1 ARHGEF25	4.31e-04	169	39	3	6ff1172da690ca17f7108f1617b255b766971a57
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LTBP1 LTBP4 ADAM15	4.31e-04	169	39	3	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	CDCA5 CCDC34 TRIM17	4.38e-04	170	39	3	5319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHSY3 DRICH1 NFATC4	4.53e-04	172	39	3	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	VIPR2 RALGPS1 IL6R	4.53e-04	172	39	3	a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHSY3 DRICH1 NFATC4	4.53e-04	172	39	3	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC17A8 CHSY3 FAM149A	4.61e-04	173	39	3	70c0c13febd28b395fb3171ec8d7fbbc6c9d4eb7
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IRS1 LTBP1 NFATC4	4.61e-04	173	39	3	f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	VIPR2 LTBP1 ARHGEF25	4.61e-04	173	39	3	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 ARHGEF25 LTBP4	4.69e-04	174	39	3	9c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 ARHGEF25 LTBP4	4.69e-04	174	39	3	bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell	Control-Lymphoid-Tregs\|Lymphoid / Condition, Lineage and Cell class	ADAM15 IL6R FAM149A	4.69e-04	174	39	3	522a6d5d9809271c63b85f62ac6ec52a6e3c355e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	KEL CDCA5 EBF4	4.77e-04	175	39	3	63e977b8bafae1c5f742fc35a4cc712fefa9727f
ToppCell	severe_influenza-Plasmablast\|World / disease group, cell group and cell class (v2)	CDCA5 CCDC34 FAM149A	4.77e-04	175	39	3	e6d6c44510d5dc4eb0bae820125e42366f7a4e74
ToppCell	21-Trachea-Epithelial-Submucosal_gland\|Trachea / Age, Tissue, Lineage and Cell class	FGFR2 NOXO1 LTBP4	5.01e-04	178	39	3	3e406e38eea0d38dc25edecf703c4c89ec6a28e0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF25 NFATC4 LTBP4	5.01e-04	178	39	3	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	VIPR2 HOXB6 NOXO1	5.18e-04	180	39	3	e53e9f3ebd48fb8237515e740ba5d9880ed6ade3
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	VIPR2 HOXB6 NOXO1	5.18e-04	180	39	3	9d18aa1044945fe6481ea3284037a777657fd837
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS15 LTBP1 LTBP4	5.26e-04	181	39	3	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HOXB6 LTBP1 LTBP4	5.26e-04	181	39	3	eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HOXB6 LTBP1 LTBP4	5.26e-04	181	39	3	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KRT4 FGFR2 FAM149A	5.35e-04	182	39	3	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 VIPR2 LTBP1	5.35e-04	182	39	3	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 VIPR2 LTBP1	5.35e-04	182	39	3	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LTBP1 LTBP4 IL6R	5.35e-04	182	39	3	19c5e3a9d9b3728303b682102e276adfe93aa759
Disease	transient cerebral ischemia (biomarker_via_orthology)	SLC17A8 LTBP1 FGFR2 SLC17A6	4.44e-05	157	37	4	DOID:224 (biomarker_via_orthology)
Disease	hip bone mineral density, hip bone size	HOXB6 FGFR2	2.26e-03	56	37	2	EFO_0004844, EFO_0007702
Disease	mosquito bite reaction size measurement	CHSY3 ADAM15 IL6R	2.37e-03	212	37	3	EFO_0008378
Disease	obesity (implicated_via_orthology)	TCF3 IRS1 WNT1	2.47e-03	215	37	3	DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
STSTPGRRSCFGFEG	CDCA5	156	Q96FF9
CFARGGRESYSIAGS	ARHGEF25	26	Q86VW2
YPVSAAGRASPCSFS	BEGAIN	431	Q9BUH8
AGRASPCSFSERYYG	BEGAIN	436	Q9BUH8
AFGSCGRNPSGSYVS	ADAM15	556	Q13444
LTGGSSDLRRCFYSG	ADAMTS15	91	Q8TE58
SRDFFSGSCAGSPYN	RFX6	736	Q8HWS3
SAGSGSARFSRRPTC	RALGPS1	306	Q5JS13
PTCSIYGRRAAGSFF	ODF3B	161	A8MYP8
GATPRDSGLYACTAS	FGFR2	96	P21802
SPYSRGSAASRAAGA	FAM149A	76	A5PLN7
RCSSGGFGSRSLYNL	KRT4	41	P19013
RYSRSSAAAGAPSRA	LTBP1	61	Q14766
GSYGFRLSCVASGPR	PDZD3	476	Q86UT5
FQPGSRCGSQSFSSY	KRT82	6	Q9NSB4
YGSSPCDFRSSFRSV	IRS1	431	P35568
SCNSSSFGPSGRRGR	HOXB6	136	P17509
FVSRCGSNFTGPSGY	CUBN	2916	O60494
SGNYSCYRAGRPAGT	IL6R	91	P08887
FPSSYAGFSADCRPR	CCDC34	11	Q96HJ3
GYARSCSSASPRGFA	EBF4	451	Q9BQW3
SCRTRFSAPASAGGY	ATOH1	271	Q92858
SGYTCACDSGFRLSP	LTBP4	566	Q8N2S1
GSFRCSCAPGYRAPS	LTBP4	856	Q8N2S1
FRATYAAFRCSPISG	CEP192	2326	Q8TEP8
YSGSLGFGSSSCRSL	KRTAP13-1	96	Q8IUC0
YSGSLGFGSSSCRSL	KRTAP13-2	96	Q52LG2
PSRVQGGCYRFDSSS	DRICH1	131	Q6PGQ1
CGKRRYSSSGTPSSA	NFATC4	266	Q14934
TGYGASCVSSGRPDR	MYCBP2	776	O75592
GSSGPQFCASRAYES	NOXO1	236	Q8NFA2
GSSLCSYYGRSAAGP	CHSY3	41	Q70JA7
RSRLATTSFCGSYAG	SLC17A6	211	Q9P2U8
PSYSGSSRRRAADGS	TCF3	151	P15923
GYDSSAPRLGRFCGS	TLL2	956	Q9Y6L7
TPSASRDYRVCGSSF	VIPR2	396	P41587
RRYLGSSPEGSGFCS	TRIM17	316	Q9Y577
PNFCTYSGRLGTAGT	WNT1	296	P04628
SGASYSREKCGVPFS	TSPAN14	171	Q8NG11
RASSRSPASCASYNF	VAV2	776	P52735
YSPGTAGRVCSREAS	WNT9B	296	O14905
RSRLATTSFCGSYAG	SLC17A8	216	Q8NDX2
SSTPAFARYFRCARG	KEL	706	P23276