Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP1B VLDLR

2.85e-0716173GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP1B VLDLR

6.75e-0721173GO:0030228
GeneOntologyMolecularFunctioncalcium ion binding

NRXN1 LRP1 ADAM8 LTBP4 LRP1B VLDLR RAB11FIP4

1.42e-06749177GO:0005509
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 LRP1B VLDLR

4.85e-0585173GO:0038024
GeneOntologyMolecularFunctionapolipoprotein binding

LRP1 VLDLR

1.28e-0420172GO:0034185
GeneOntologyMolecularFunctioncalcium-dependent protein binding

NRXN1 VLDLR

3.09e-0398172GO:0048306
GeneOntologyMolecularFunctionmetalloendopeptidase activity

MMP11 ADAM8

4.59e-03120172GO:0004222
GeneOntologyMolecularFunctionendopeptidase activity

MMP11 ADAM8 USP9X

5.39e-03430173GO:0004175
GeneOntologyMolecularFunctionintegrin binding

ADAM8 LTBP4

9.53e-03175172GO:0005178
GeneOntologyMolecularFunctionserine-type endopeptidase activity

MMP11 ADAM8

1.12e-02190172GO:0004252
GeneOntologyMolecularFunctionmetallopeptidase activity

MMP11 ADAM8

1.23e-02200172GO:0008237
GeneOntologyMolecularFunctionserine-type peptidase activity

MMP11 ADAM8

1.31e-02207172GO:0008236
GeneOntologyMolecularFunctioncell adhesion molecule binding

NRXN1 ADAM8 LTBP4

1.33e-02599173GO:0050839
GeneOntologyMolecularFunctionserine hydrolase activity

MMP11 ADAM8

1.37e-02212172GO:0017171
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

LRP1 LTBP4 USP9X SPRED3 MAPK7

8.01e-06336185GO:0071560
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

LRP1 LTBP4 USP9X SPRED3 MAPK7

8.86e-06343185GO:0071559
GeneOntologyBiologicalProcessextracellular matrix disassembly

MMP11 LRP1 ADAM8

3.62e-0575183GO:0022617
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

NRXN1 LRP1 LTBP4 USP9X SPRED3 MAPK7

5.83e-05850186GO:0071363
GeneOntologyBiologicalProcessresponse to growth factor

NRXN1 LRP1 LTBP4 USP9X SPRED3 MAPK7

7.21e-05883186GO:0070848
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

LRP1 LTBP4 USP9X SPRED3

8.28e-05276184GO:0007179
GeneOntologyBiologicalProcesscell junction assembly

NRXN1 LRP1 ELFN1 VLDLR USP9X

9.98e-05569185GO:0034329
GeneOntologyBiologicalProcesssynapse assembly

NRXN1 ELFN1 VLDLR USP9X

1.26e-04308184GO:0007416
GeneOntologyBiologicalProcessregulation of cell junction assembly

NRXN1 LRP1 VLDLR USP9X

1.28e-04309184GO:1901888
GeneOntologyBiologicalProcessextracellular matrix organization

MMP11 LRP1 ADAM8 LTBP4

2.74e-04377184GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

MMP11 LRP1 ADAM8 LTBP4

2.77e-04378184GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

MMP11 LRP1 ADAM8 LTBP4

2.80e-04379184GO:0045229
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

NRXN1 LRP1 LTBP4 SPRED3

3.84e-04412184GO:0090287
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

LRP1 LTBP4 USP9X SPRED3

5.14e-04445184GO:0141091
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

LRP1 LTBP4 SPRED3

5.85e-04192183GO:0017015
GeneOntologyBiologicalProcesssynaptic membrane adhesion

NRXN1 ELFN1

6.07e-0442182GO:0099560
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

LRP1 LTBP4 SPRED3

6.11e-04195183GO:1903844
GeneOntologyBiologicalProcessregulation of synapse assembly

NRXN1 VLDLR USP9X

6.78e-04202183GO:0051963
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

LRP1 LTBP4 USP9X SPRED3

6.95e-04482184GO:0007178
GeneOntologyBiologicalProcesscerebellar cortex morphogenesis

NRXN1 USP9X

7.92e-0448182GO:0021696
GeneOntologyBiologicalProcessMAPK cascade

NRXN1 LRP1 ADAM8 SPRED3 MAPK7

9.66e-04930185GO:0000165
GeneOntologyBiologicalProcesscell junction organization

NRXN1 LRP1 ELFN1 VLDLR USP9X

1.19e-03974185GO:0034330
GeneOntologyBiologicalProcesscerebellum morphogenesis

NRXN1 USP9X

1.24e-0360182GO:0021587
GeneOntologyBiologicalProcesspositive regulation of neuron projection development

NRXN1 LRP1 VLDLR

1.24e-03249183GO:0010976
GeneOntologyBiologicalProcesshindbrain morphogenesis

NRXN1 USP9X

1.40e-0364182GO:0021575
GeneOntologyBiologicalProcesspositive regulation of protein localization to plasma membrane

NRXN1 LRP1

1.68e-0370182GO:1903078
GeneOntologyBiologicalProcesscerebellar cortex development

NRXN1 USP9X

1.72e-0371182GO:0021695
GeneOntologyBiologicalProcesssignal release

NRXN1 LRP1 ADAM8 LTBP4

2.14e-03653184GO:0023061
GeneOntologyBiologicalProcesspositive regulation of protein localization to cell periphery

NRXN1 LRP1

2.29e-0382182GO:1904377
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

NRXN1 ELFN1 MAPK7

2.38e-03313183GO:0098742
GeneOntologyBiologicalProcesspositive regulation of protein binding

LRP1 USP9X

2.46e-0385182GO:0032092
GeneOntologyBiologicalProcesssynapse organization

NRXN1 ELFN1 VLDLR USP9X

2.54e-03685184GO:0050808
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

NRXN1 LRP1 LTBP4 USP9X SPRED3

2.85e-031186185GO:0007167
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

NRXN1 LRP1 VLDLR USP9X SLX1A

2.88e-031189185GO:0044087
GeneOntologyBiologicalProcesscell morphogenesis

NRXN1 LRP1 ADAM8 VLDLR USP9X

2.93e-031194185GO:0000902
GeneOntologyBiologicalProcesspostsynapse assembly

NRXN1 USP9X

2.94e-0393182GO:0099068
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

LRP1 LRP1B VLDLR

2.94e-03337183GO:0006898
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 LTBP4 SPRED3

3.19e-03347183GO:0090092
GeneOntologyBiologicalProcessprotein K48-linked ubiquitination

RNF187 TRIM44

3.38e-03100182GO:0070936
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

NRXN1 LRP1 VLDLR USP9X

3.50e-03748184GO:0048667
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

LRP1 ADAM8 MAPK7

3.97e-03375183GO:0007162
GeneOntologyBiologicalProcesspositive regulation of intracellular signal transduction

NRXN1 LRP1 ADAM8 TRIM44 USP9X

4.22e-031299185GO:1902533
GeneOntologyBiologicalProcessregulation of ERK1 and ERK2 cascade

NRXN1 LRP1 SPRED3

4.28e-03385183GO:0070372
GeneOntologyBiologicalProcessregulation of synapse organization

NRXN1 VLDLR USP9X

4.34e-03387183GO:0050807
GeneOntologyBiologicalProcessregulation of response to external stimulus

NRXN1 LRP1 ADAM8 TRIM44 MAPK7

4.46e-031316185GO:0032101
GeneOntologyBiologicalProcessneuron projection morphogenesis

NRXN1 LRP1 VLDLR USP9X

4.49e-03802184GO:0048812
GeneOntologyBiologicalProcessregulation of synapse structure or activity

NRXN1 VLDLR USP9X

4.59e-03395183GO:0050803
GeneOntologyBiologicalProcessregulation of MAPK cascade

NRXN1 LRP1 ADAM8 SPRED3

4.75e-03815184GO:0043408
GeneOntologyBiologicalProcessblood vessel morphogenesis

NRXN1 LRP1 ADAM8 MAPK7

4.79e-03817184GO:0048514
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

NRXN1 LRP1 VLDLR USP9X

4.84e-03819184GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

NRXN1 LRP1 VLDLR USP9X

4.99e-03826184GO:0048858
GeneOntologyCellularComponentendocytic vesicle

NRXN1 LRP1 ADAM8 RAB11FIP4

2.80e-04384184GO:0030139
GeneOntologyCellularComponentdistal axon

NRXN1 LRP1 ELFN1 USP9X

4.49e-04435184GO:0150034
GeneOntologyCellularComponentaxonal growth cone

NRXN1 LRP1

6.78e-0445182GO:0044295
GeneOntologyCellularComponentgrowth cone

NRXN1 LRP1 USP9X

1.14e-03245183GO:0030426
GeneOntologyCellularComponentsite of polarized growth

NRXN1 LRP1 USP9X

1.25e-03253183GO:0030427
GeneOntologyCellularComponentclathrin-coated pit

LRP1 VLDLR

2.13e-0380182GO:0005905
GeneOntologyCellularComponentexcitatory synapse

NRXN1 ELFN1

3.76e-03107182GO:0060076
DomainASX_HYDROXYL

NRXN1 LRP1 LTBP4 LRP1B VLDLR

2.34e-08100175PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NRXN1 LRP1 LTBP4 LRP1B VLDLR

3.14e-08106175IPR000152
DomainEGF

NRXN1 LRP1 ADAM8 LTBP4 LRP1B VLDLR

4.10e-08235176SM00181
DomainEGF_3

NRXN1 LRP1 ADAM8 LTBP4 LRP1B VLDLR

4.10e-08235176PS50026
DomainEGF-like_dom

NRXN1 LRP1 ADAM8 LTBP4 LRP1B VLDLR

5.79e-08249176IPR000742
DomainEGF_1

NRXN1 LRP1 ADAM8 LTBP4 LRP1B VLDLR

6.66e-08255176PS00022
DomainEGF-like_CS

NRXN1 LRP1 ADAM8 LTBP4 LRP1B VLDLR

7.65e-08261176IPR013032
DomainEGF_2

NRXN1 LRP1 ADAM8 LTBP4 LRP1B VLDLR

8.37e-08265176PS01186
DomainLdl_recept_b

LRP1 LRP1B VLDLR

2.27e-0714173PF00058
DomainLDLRB

LRP1 LRP1B VLDLR

2.27e-0714173PS51120
DomainLY

LRP1 LRP1B VLDLR

2.83e-0715173SM00135
DomainLDLR_classB_rpt

LRP1 LRP1B VLDLR

2.83e-0715173IPR000033
DomainDUF5050

LRP1 LRP1B

7.80e-072172PF16472
DomainDUF5050

LRP1 LRP1B

7.80e-072172IPR032485
DomainEGF_CA

LRP1 LTBP4 LRP1B VLDLR

9.53e-0786174PF07645
DomainEGF_Ca-bd_CS

LRP1 LTBP4 LRP1B VLDLR

1.54e-0697174IPR018097
DomainEGF_CA

LRP1 LTBP4 LRP1B VLDLR

1.68e-0699174PS01187
DomainEGF_CA

LRP1 LTBP4 LRP1B VLDLR

3.86e-06122174SM00179
DomainEGF-like_Ca-bd_dom

LRP1 LTBP4 LRP1B VLDLR

4.12e-06124174IPR001881
DomainEGF

NRXN1 LRP1 LRP1B VLDLR

4.39e-06126174PF00008
Domain-

LRP1 LRP1B VLDLR

5.61e-06391732.120.10.30
DomainLDLR_class-A_CS

LRP1 LRP1B VLDLR

6.06e-0640173IPR023415
DomainLdl_recept_a

LRP1 LRP1B VLDLR

8.68e-0645173PF00057
Domain-

LRP1 LRP1B VLDLR

9.28e-06461734.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP1 LRP1B VLDLR

9.28e-0646173IPR011042
DomainGrowth_fac_rcpt_

LRP1 LTBP4 LRP1B VLDLR

1.02e-05156174IPR009030
DomainLDLRA_1

LRP1 LRP1B VLDLR

1.06e-0548173PS01209
DomainLDLa

LRP1 LRP1B VLDLR

1.12e-0549173SM00192
DomainLDLRA_2

LRP1 LRP1B VLDLR

1.12e-0549173PS50068
DomainLDrepeatLR_classA_rpt

LRP1 LRP1B VLDLR

1.12e-0549173IPR002172
DomaincEGF

LRP1 LRP1B

2.50e-0426172PF12662
DomaincEGF

LRP1 LRP1B

2.50e-0426172IPR026823
DomainEGF_extracell

ADAM8 LRP1B

1.34e-0360172IPR013111
DomainEGF_2

ADAM8 LRP1B

1.34e-0360172PF07974
Domain-

MMP11 ADAM8

2.42e-03811723.40.390.10
DomainMetalloPept_cat_dom

MMP11 ADAM8

2.42e-0381172IPR024079
DomainZINC_PROTEASE

MMP11 ADAM8

3.52e-0398172PS00142
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_3

LRP1 VLDLR

7.10e-0513142M42551
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

MMP11 NRXN1 ADAM8 LTBP4

1.70e-04300144M610
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP1B VLDLR

4.22e-081418315082773
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP1B VLDLR

1.54e-072118321337463
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

2.53e-07218215963947
Pubmed

Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.

LRP1 VLDLR

2.53e-07218215327526
Pubmed

The relationship among apolipoprotein(a) polymorphisms, the low-density lipoprotein receptor-related protein, and the very low density lipoprotein receptor genes, and plasma lipoprotein(A) concentration in the Czech population.

LRP1 VLDLR

7.59e-07318211931574
Pubmed

The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.

LRP1 VLDLR

7.59e-07318218277139
Pubmed

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.

LRP1 VLDLR

7.59e-07318218367731
Pubmed

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.

LRP1 VLDLR

1.52e-06418215863833
Pubmed

LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo.

LRP1 VLDLR

1.52e-06418215840700
Pubmed

Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19.

LRP1 VLDLR

2.53e-0651828013374
Pubmed

Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.

LRP1 VLDLR

2.53e-06518212746448
Pubmed

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.

LRP1 VLDLR

2.53e-06518218992221
Pubmed

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.

LRP1 VLDLR

2.53e-06518223959870
Pubmed

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.

LRP1 VLDLR

2.53e-06518230700132
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

LRP1 VLDLR

2.53e-06518218685438
Pubmed

Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.

LRP1 VLDLR

3.79e-06618216478678
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP1 VLDLR

5.30e-06718212169628
Pubmed

Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes.

LRP1 VLDLR

5.30e-06718223760271
Pubmed

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

LRP1 VLDLR

7.07e-06818210380922
Pubmed

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

LRP1 VLDLR

9.09e-06918220005821
Pubmed

Targeted inactivation of the mouse alpha 2-macroglobulin gene.

LRP1 VLDLR

9.09e-0691827544347
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP1B

1.39e-051118224639464
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP1 LRP1B VLDLR

1.88e-0510118323382219
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 VLDLR

2.29e-051418217389516
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

LRP1 VLDLR

3.85e-051818210827173
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

MMP11 LTBP4

1.58e-043618220587546
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

LRP1 LRP1B VLDLR USP9X RAB11FIP4

3.91e-04128518535914814
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

MMP11 LRP1 LRP1B USP9X

4.66e-0473018434857952
InteractionZNF408 interactions

LTBP4 LRP1B VLDLR USP9X

7.27e-06145184int:ZNF408
InteractionZFP41 interactions

LRP1 LTBP4 LRP1B

1.70e-0557183int:ZFP41
InteractionANKRD36B interactions

LRP1 LRP1B VLDLR

1.98e-0560183int:ANKRD36B
InteractionZNF563 interactions

LTBP4 LRP1B

4.95e-0512182int:ZNF563
InteractionSYT1 interactions

NRXN1 LRP1B VLDLR

1.06e-04105183int:SYT1
InteractionMMP16 interactions

MMP11 LRP1

1.14e-0418182int:MMP16
InteractionNTN5 interactions

LTBP4 LRP1B

2.06e-0424182int:NTN5
InteractionZNF517 interactions

LTBP4 LRP1B

3.02e-0429182int:ZNF517
InteractionELFN2 interactions

ELFN1 RAB11FIP4

3.02e-0429182int:ELFN2
InteractionMMP13 interactions

MMP11 LRP1

3.45e-0431182int:MMP13
InteractionZNF74 interactions

RNF187 LTBP4

4.16e-0434182int:ZNF74
InteractionLDLR interactions

LRP1B EPC2 VLDLR USP9X

4.39e-04417184int:LDLR
InteractionLPL interactions

LRP1 VLDLR

4.41e-0435182int:LPL
InteractionRNF187 interactions

RNF187 TRIM44

4.66e-0436182int:RNF187
InteractionMZF1 interactions

LTBP4 USP9X

4.93e-0437182int:MZF1
InteractionLRPAP1 interactions

LRP1 LRP1B VLDLR

5.18e-04180183int:LRPAP1
GeneFamilyLow density lipoprotein receptors

LRP1 LRP1B VLDLR

6.36e-0813123634
GeneFamilyRing finger proteins

RNF187 TRIM44

1.38e-0227512258
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_UP

LRP1 EPC2 TRIM44 USP9X

9.26e-06200184M6629
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

NRXN1 SRRM3 LRP1B SPRED3 RAB11FIP4

8.77e-05703185M39070
CoexpressionLEE_BMP2_TARGETS_UP

MMP11 LRP1 LTBP4 HAGHL VLDLR

1.43e-04780185M2324
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

NRXN1 USP9X

1.55e-0427182M14833
CoexpressionLEE_BMP2_TARGETS_UP

MMP11 LRP1 LTBP4 HAGHL VLDLR

1.66e-04805185MM1067
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

NRXN1 USP9X

2.32e-0433182MM477
CoexpressionGSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_DN

MMP11 LRP1 VLDLR

3.05e-04195183M9309
CoexpressionGSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_UP

RNF187 LRP1 MAPK7

3.23e-04199183M9351
CoexpressionGSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP

MMP11 ADAM8 LTBP4

3.23e-04199183M5203
CoexpressionGSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP

HAGHL VLDLR TRIM44

3.28e-04200183M6990
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000

MMP11 NRXN1 SRRM3 LTBP4 HAGHL USP9X RAB11FIP4

8.53e-06974187Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#3

NRXN1 SRRM3 LTBP4 USP9X

1.01e-05166184Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K3
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500_k-means-cluster#3

MMP11 SRRM3 RAB11FIP4

2.37e-0567183Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_500_K3
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500

MMP11 SRRM3 HAGHL USP9X RAB11FIP4

4.24e-05489185Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#3

NRXN1 SRRM3 LTBP4 EPC2

6.90e-05271184Facebase_RNAseq_e10.5_Mandibular Arch_1000_K3
CoexpressionAtlascerebral cortex

NRXN1 SRRM3 LRP1B HAGHL ELFN1 SPRED3 RAB11FIP4

1.01e-041428187cerebral cortex
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#3_top-relative-expression-ranked_100

VLDLR USP9X

1.55e-0422182gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_100_k3
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MMP11 LRP1 SRRM3 LTBP4

1.08e-061991846b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 VLDLR RAB11FIP4

2.43e-05142183a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 VLDLR RAB11FIP4

2.43e-05142183d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NRXN1 SRRM3 SPRED3

3.40e-051591837747cef94c55144fddcd024a7495318357f1351b
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LRP1B MAPK7

3.66e-05163183b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LRP1B MAPK7

3.66e-05163183360cd65decda24853124f33a174f5224d7f3ce23
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

MMP11 LRP1B ELFN1

3.93e-051671835af9127bae05768a5164d5708a4ad37edca99324
ToppCelldroplet-Heart-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 VLDLR

4.08e-051691832e5bb6437bc9c614e337c5ffb6f6457cd9fc7f4c
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRXN1 LRP1 LRP1B

4.15e-051701835570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LRP1 LTBP4 VLDLR

4.37e-05173183b23b408acc29a667cce104429afef1a6cf2720a5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN1 LRP1 LTBP4

4.45e-051741839c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN1 LRP1 LTBP4

4.45e-05174183bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP11 ELFN1 VLDLR

4.52e-05175183cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP11 ELFN1 VLDLR

4.52e-0517518396219e58dcb327fd27190be78193e7a0d611e62b
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 VLDLR MAPK7

5.08e-05182183ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 LRP1 ELFN1

5.25e-051841838d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 LRP1 ELFN1

5.25e-05184183278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 VLDLR

5.42e-05186183f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN1 LRP1 LTBP4

5.59e-05188183c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN1 LRP1 LTBP4

5.59e-051881831cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 LTBP4 VLDLR

5.59e-051881833f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LTBP4 VLDLR

5.68e-0518918340cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 LTBP4 MAPK7

5.68e-051891830c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellfacs-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LTBP4 VLDLR

5.68e-05189183bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCellfacs-GAT-Fat-24m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP11 LRP1 LTBP4

5.77e-051901833720e64129f3f3268b1dc14031a76f41c38241c2
ToppCellfacs-GAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP11 LRP1 LTBP4

5.77e-0519018373a50426f972f08f9bb525ad5c0b774187ab5d6a
ToppCellfacs-GAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP11 LRP1 LTBP4

5.77e-05190183b55cf1fb586b724295b7b038483249847bb344fc
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 LRP1 ELFN1

5.77e-05190183d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 LRP1 ELFN1

5.77e-051901839b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCellfacs-GAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP11 LTBP4 VLDLR

5.86e-051911831f5d1e8c313a8dc83c06d2ee45f369b0ec507fbf
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LRP1 LTBP4

5.86e-05191183094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LTBP4 VLDLR

5.86e-051911838a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MMP11 NRXN1 LRP1B

5.86e-05191183156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LRP1 LTBP4

5.86e-051911835c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LTBP4 VLDLR

5.86e-05191183b5210de890d338602857b5907135705a507bc2b0
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

LRP1 SRRM3 VLDLR

5.86e-05191183e7c605b56934d1383237c1f946dbccef25d91368
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 LTBP4 VLDLR

5.86e-051911833379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LTBP4 VLDLR

5.86e-05191183c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LTBP4 VLDLR

5.86e-05191183997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LRP1 LTBP4

5.86e-0519118380484d39f34703a33b9bac09826b7a526e883cab
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LTBP4 VLDLR

5.86e-05191183243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 LTBP4 VLDLR

5.96e-0519218325492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LTBP4 VLDLR

5.96e-051921832d3790bd80a7f214b37094121a2a86ff16362569
ToppCellP03-Mesenchymal-mesenchymal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 LTBP4 VLDLR

5.96e-05192183e79f2253e084a9ab9afcaf7ec42a5012ade42d36
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 LTBP4 VLDLR

5.96e-05192183de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP11 LTBP4 VLDLR

5.96e-05192183ff4b728a55c2550c806c47e9ae3d057c35df8464
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP11 LRP1 LTBP4

5.96e-051921835876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP11 LRP1 LTBP4

6.05e-051931834c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCellfacs-MAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP11 LRP1 LTBP4

6.05e-05193183733f557bdc80293b40ccdf560f1675793df932d6
ToppCellfacs-MAT-Fat-24m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP11 LRP1 LTBP4

6.05e-05193183eb3c46b6fb06dc8708dc3032189b47ed93ee2357
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MMP11 NRXN1 VLDLR

6.05e-05193183cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP11 LRP1 LTBP4

6.05e-05193183ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 VLDLR

6.05e-05193183ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 VLDLR

6.05e-0519318322c58032e58730715224d7934968ce92d150b0e8
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 VLDLR

6.05e-05193183573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MMP11 LRP1 LTBP4

6.05e-05193183dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MMP11 LRP1 LTBP4

6.05e-05193183e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellfacs-MAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP11 LRP1 LTBP4

6.05e-05193183b45cd02081f97904eaea2d013e1fa980505d060b
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 VLDLR

6.14e-05194183f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 VLDLR

6.14e-0519418354a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 VLDLR

6.14e-05194183da926441053b499cb5107ccb116fb1b3844d82b7
ToppCellP03-Mesenchymal|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 LTBP4 VLDLR

6.24e-051951836180309c6ae278b996fd98c57461cbc129c028ba
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MMP11 NRXN1 SRRM3

6.33e-0519618395544097577f20ed7f4144bd940471cde0617554
ToppCellE18.5-Mesenchymal-Mesenchymal_structural|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 LTBP4 VLDLR

6.33e-0519618397e26622d9582b092c18ff5b7e957818f99d9631
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 LTBP4 VLDLR

6.33e-05196183f429f045ba45e24717963315832150b12a115bfa
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MMP11 LRP1 LTBP4

6.43e-051971834cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 LRP1B

6.52e-05198183ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 LRP1B

6.52e-05198183abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 VLDLR

6.52e-051981830dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell3'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 LRP1B

6.52e-05198183698166b4ca173176ed563af6a1efc8c7d0a18e0b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP11 LRP1 LTBP4

6.62e-05199183e78f661b40da34768469549b6e755d330be6bbd8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NRXN1 LRP1 LRP1B

6.62e-0519918319a97e27a4758e794ce7246d295e112b47931a48
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP11 LRP1 LTBP4

6.62e-05199183edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MMP11 LRP1 LTBP4

6.62e-0519918338cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

NRXN1 SRRM3 USP9X

6.72e-05200183ac0e023dbb383bbc46c5cc525431778be8f7ef46
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

LTBP4 ELFN1 VLDLR

6.72e-05200183b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

MMP11 LRP1 LTBP4

6.72e-05200183a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MMP11 LRP1 LTBP4

6.72e-0520018309537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LTBP4 ELFN1 VLDLR

6.72e-05200183ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Mme_Fam114a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MMP11 ELFN1

8.52e-041081824536cbe1748aee37f0a13648c5679fd592af6322
ToppCellBronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NRXN1 SPRED3

9.81e-04116182b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRXN1 LRP1B

1.19e-0312818291072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

LRP1 LTBP4

1.21e-0312918213cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRXN1 LRP1B

1.23e-031301821ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellCOVID-19-kidney-Epithelial_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRXN1 LRP1B

1.29e-03133182a8abb6b54862123961ae6defbf251ee6e9575258
ToppCellRA-15._Ventricular_Cardiomyocyte_III|RA / Chamber and Cluster_Paper

MMP11 SPRED3

1.31e-0313418260ee3accc54108e5b9a0018f6aa8488dc39d5ade
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-3|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

LRP1 MAPK7

1.34e-031361824f5e0b6c7d6e3e922af4daa7c3eb56490455c1df
ToppCellRA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MMP11 SPRED3

1.38e-031381825a713f24f633de463ef47ca37fbb2bb60c7fdb77
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRXN1 LRP1B

1.40e-03139182a1945b07f177cde40e7eea03a19236ce76165857
ToppCellCOVID-19-kidney-Technical/muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRXN1 LRP1B

1.40e-0313918213247bcb21c57c808657e0f543d6f134eeea7cc1
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 MAPK7

1.42e-03140182e442c46979d725ec82f525a001c46d971fcade4d
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NRXN1 SRRM3

1.46e-03142182819e983688d126d89a71abc03d72525cc759a347
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAM8 SPRED3

1.48e-031431825a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 ELFN1

1.51e-03144182121853910eeea1ea0642b3cc99f9200015480368
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM8 SPRED3

1.53e-03145182997bd540c43725a85ca97e4b79ebe0d336860287
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM8 RAB11FIP4

1.53e-0314518288e463d5396a8fea2b7b1ecf3c9b144e16b35234
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM8 RAB11FIP4

1.53e-03145182911fee7f27694393e348d94470a1a4e890038902
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SRRM3

1.53e-0314518207acbf086cffce0628accf078d31bf190f803988
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP11 SRRM3

1.55e-0314618286cddd0e7f954547b7ffdccb0329cd5c4b725ac1
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRXN1 LRP1B

1.59e-03148182d6ac5972267254651dfbe16bb4e9a62228093cc7
DrugMeclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

ADAM8 LTBP4 LRP1B MAPK7

1.51e-051971844729_UP
Drughaloperidol; Down 200; 10uM; PC3; HT_HG-U133A

LRP1 ADAM8 LTBP4 MAPK7

1.54e-051981844468_DN
Drug1-4a

MMP11 USP9X SLX1A

2.29e-0571183CID000657007
DrugSuccimer

MMP11 LRP1 ADAM8 HAGHL VLDLR TRIM44 USP9X

2.96e-051264187ctd:D004113
DrugMagnetite Nanoparticles

MMP11 LRP1 ADAM8 HAGHL VLDLR TRIM44 USP9X

3.73e-051310187ctd:D058185
Drugtroglitazone

LRP1 LRP1B VLDLR SLX1A MAPK7

4.31e-05526185CID000005591
Drugmonatepil

LRP1 LRP1B

2.37e-0429182CID000060810
Drugprobucol

LRP1 LRP1B VLDLR

2.67e-04162183CID000004912
Drugethylnylestradiol

MMP11 LRP1 LRP1B VLDLR SLX1A MAPK7

2.85e-041251186CID000003285
DrugCyclosporin A [59865-13-3]; Up 200; 3.4uM; MCF7; HT_HG-U133A

ADAM8 LTBP4 VLDLR

3.02e-041691834411_UP
DrugTetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; HL60; HT_HG-U133A

LRP1 ADAM8 MAPK7

3.35e-041751832507_UP
DrugDNOC

VLDLR SLX1A

3.46e-0435182CID000010800
DrugRaloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A

LTBP4 VLDLR MAPK7

3.81e-041831833480_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

MMP11 VLDLR MAPK7

4.19e-041891835586_UP
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A

MMP11 LRP1 MAPK7

4.26e-041901834274_UP
DrugNocodazole [31430-18-9]; Up 200; 13.2uM; PC3; HT_HG-U133A

LRP1 VLDLR MAPK7

4.26e-041901837145_UP
DrugMonobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A

MMP11 VLDLR MAPK7

4.39e-041921833391_UP
DrugFlunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A

LRP1 ADAM8 MAPK7

4.39e-041921834303_UP
DrugSelegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; MCF7; HT_HG-U133A

MMP11 ADAM8 LTBP4

4.46e-041931834146_UP
DrugZidovudine, AZT [30516-87-1]; Down 200; 15uM; PC3; HT_HG-U133A

LRP1 ADAM8 MAPK7

4.46e-041931836733_DN
DrugErgocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A

MMP11 LTBP4 VLDLR

4.52e-041941833900_UP
DrugMegestrol acetate [595-33-5]; Down 200; 10.4uM; PC3; HT_HG-U133A

LRP1 ADAM8 MAPK7

4.52e-041941836667_DN
DrugHydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

MMP11 ADAM8 MAPK7

4.59e-041951834746_UP
DrugGanciclovir [82410-32-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A

MMP11 ADAM8 MAPK7

4.66e-041961833368_UP
DrugTocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

LTBP4 VLDLR MAPK7

4.66e-041961833256_UP
DrugAminocaproic acid [60-32-2]; Up 200; 30.4uM; MCF7; HT_HG-U133A

MMP11 LTBP4 MAPK7

4.66e-041961836501_UP
Drug2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A

LTBP4 VLDLR MAPK7

4.66e-041961836934_UP
DrugBeta-sistosterol [83-46-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A

ADAM8 LTBP4 MAPK7

4.66e-041961834154_UP
DrugBetulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

MMP11 ADAM8 LTBP4

4.73e-041971834181_UP
DrugPyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A

MMP11 LTBP4 VLDLR

4.73e-041971832839_UP
DrugDropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A

MMP11 LRP1 MAPK7

4.73e-041971835106_UP
DrugClonidine hydrochloride [4205-91-8]; Up 200; 15uM; MCF7; HT_HG-U133A

MMP11 LTBP4 MAPK7

4.73e-041971836814_UP
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; MCF7; HT_HG-U133A

MMP11 LTBP4 MAPK7

4.73e-041971833355_UP
DrugCrotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A

MMP11 ADAM8 MAPK7

4.73e-041971833388_UP
DrugFlutamide [13311-84-7]; Up 200; 14.4uM; PC3; HT_HG-U133A

LRP1 LTBP4 VLDLR

4.80e-041981833803_UP
DrugSulfamerazine [127-79-7]; Up 200; 15.2uM; PC3; HT_HG-U133A

MMP11 LRP1 LTBP4

4.87e-041991833718_UP
DrugTomatidine [77-59-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A

LTBP4 VLDLR MAPK7

4.94e-042001837166_UP
Diseasefacial attractiveness measurement

LRP1B RAB11FIP4

5.31e-0519172EFO_0009892
Diseasekeratoconus

LRP1B RAB11FIP4

6.56e-0466172MONDO_0015486
Diseaseschizophrenia (implicated_via_orthology)

NRXN1 ELFN1

6.96e-0468172DOID:5419 (implicated_via_orthology)
Diseasesevere acute respiratory syndrome, COVID-19

NRXN1 LRP1B USP9X

2.00e-03447173EFO_0000694, MONDO_0100096
Diseasecarotid artery intima media thickness

LRP1 LTBP4 LRP1B

2.04e-03450173EFO_0007117
DiseaseAlzheimer's disease (is_implicated_in)

LRP1 VLDLR

2.58e-03132172DOID:10652 (is_implicated_in)
Diseaseepilepsy (implicated_via_orthology)

LRP1 LRP1B

3.91e-03163172DOID:1826 (implicated_via_orthology)
Diseasepain

NRXN1 LRP1

5.59e-03196172EFO_0003843

Protein segments in the cluster

PeptideGeneStartEntry
SEPEEENDPDGPCAF

EPC2

386

Q52LR7
PPEPSDMPCADDECF

ELFN1

281

P0C7U0
EEFCDGRHPECPEDA

ADAM8

476

P78325
EGDDVDCAPSSPCPD

RAB11FIP4

221

Q86YS3
EDDCPDPPALFSGDA

HAGHL

121

Q6PII5
HDPDDEPDCAPPFDF

MAPK7

351

Q13164
EPDCAPPFDFAFDRE

MAPK7

356

Q13164
AECPSDDEDIDPCEP

NRXN1

351

P58400
LCDGDPDCPDDSDES

LRP1B

51

Q9NZR2
DCGDGSDEPDDCPEF

LRP1B

3341

Q9NZR2
EDDCGDHSDEPPDCP

LRP1

3356

Q07954
AECPSDDEDIDPCEP

NRXN1

1356

Q9ULB1
ACEEDVDECAQEPPP

LTBP4

706

Q8N2S1
EPDAPPDACEASFDA

MMP11

286

P24347
CELCPEEEPDDQDAP

USP9X

2471

Q93008
PFDDDDGPVDCDCPA

SRRM3

131

A6NNA2
GTCDECEPDEAPGAE

TRIM44

16

Q96DX7
AEEDGPFPCPECADD

RNF187

41

Q5TA31
AEGDFSDPCACEPGH

SPRED3

346

Q2MJR0
DDAEPEPDQGDPGAC

SLX1A

171

Q9BQ83
CDGDPDCEDGSDESP

VLDLR

91

P98155