Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A2 MUC5AC COL7A1

2.19e-04188133GO:0005201
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A2 COL7A1

3.98e-0446132GO:0030020
GeneOntologyCellularComponentGolgi lumen

MUC5AC F10 GPC4

3.80e-05109133GO:0005796
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A2 COL7A1

7.45e-0521132GO:0098644
GeneOntologyCellularComponentextracellular matrix

COL4A2 MUC5AC COL7A1 GPC4

5.48e-04656134GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A2 MUC5AC COL7A1 GPC4

5.54e-04658134GO:0030312
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL4A2 COL7A1 F10

1.01e-03332133GO:0005788
GeneOntologyCellularComponentcollagen trimer

COL4A2 COL7A1

1.33e-0388132GO:0005581
GeneOntologyCellularComponentbasement membrane

COL4A2 COL7A1

2.53e-03122132GO:0005604
GeneOntologyCellularComponentexternal side of plasma membrane

SCART1 F10 GPC4

3.61e-03519133GO:0009897
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL4A2 COL7A1 GPC4

3.83e-03530133GO:0062023
GeneOntologyCellularComponentcell surface

SCART1 F10 NOTCH4 GPC4

3.86e-031111134GO:0009986
GeneOntologyCellularComponentside of membrane

SCART1 F10 GPC4

1.53e-02875133GO:0098552
DomainCollagen

COL4A2 COL7A1

1.31e-0385122PF01391
DomainCollagen

COL4A2 COL7A1

1.31e-0385122IPR008160
DomainEGF_Ca-bd_CS

F10 NOTCH4

1.70e-0397122IPR018097
DomainEGF_CA

F10 NOTCH4

1.77e-0399122PS01187
DomainASX_HYDROXYL

F10 NOTCH4

1.81e-03100122PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

F10 NOTCH4

2.03e-03106122IPR000152
DomainEGF_CA

F10 NOTCH4

2.68e-03122122SM00179
DomainEGF-like_Ca-bd_dom

F10 NOTCH4

2.76e-03124122IPR001881
DomainEGF

F10 NOTCH4

2.85e-03126122PF00008
DomainEGF

F10 NOTCH4

9.57e-03235122SM00181
DomainEGF_3

F10 NOTCH4

9.57e-03235122PS50026
DomainEGF-like_dom

F10 NOTCH4

1.07e-02249122IPR000742
DomainEGF_1

F10 NOTCH4

1.12e-02255122PS00022
DomainEGF-like_CS

F10 NOTCH4

1.17e-02261122IPR013032
DomainEGF_2

F10 NOTCH4

1.21e-02265122PS01186
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A2 COL7A1

5.78e-0515112M27161
PathwayBIOCARTA_AMI_PATHWAY

COL4A2 F10

1.04e-0420112M15394
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A2 F10

1.39e-0423112M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A2 F10

1.39e-0423112MM1427
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC5AC NOTCH4 GPC4

1.59e-04143113M27275
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A2 COL7A1

2.38e-0430112M27216
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL7A1

4.46e-0441112MM15538
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL7A1

5.14e-0444112M27812
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 COL7A1

6.64e-0450112MM14796
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A2 COL7A1

7.46e-0453112MM14566
PathwayREACTOME_NEGATIVE_REGULATION_OF_NOTCH4_SIGNALING

PSMC6 NOTCH4

7.75e-0454112M27931
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC5AC NOTCH4 GPC4

8.18e-04250113M27554
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 COL7A1

9.88e-0461112M27103
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A2 COL7A1

9.88e-0461112MM14637
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A2 COL7A1

1.09e-0364112M26953
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A2 COL7A1

1.19e-0367112M26999
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC5AC NOTCH4

1.23e-0368112M27303
PathwayREACTOME_COLLAGEN_FORMATION

COL4A2 COL7A1

1.53e-0376112MM14573
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A2 COL7A1

1.53e-0376112MM14867
PathwayREACTOME_SIGNALING_BY_NOTCH4

PSMC6 NOTCH4

1.78e-0382112M594
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A2 COL7A1

1.91e-0385112M16441
PathwayREACTOME_COLLAGEN_FORMATION

COL4A2 COL7A1

2.14e-0390112M631
PathwayWP_NEURAL_CREST_DIFFERENTIATION

ZIC5 NOTCH4

2.48e-0397112MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

ZIC5 NOTCH4

2.68e-03101112M39448
Pubmed

NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis.

FOSB NOTCH4

7.74e-07413237478314
Pubmed

Homologs of genes and anonymous loci on human chromosome 13 map to mouse chromosomes 8 and 14.

COL4A2 F10

2.71e-0671327613031
Pubmed

Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.

MUC5AC GPC4

1.97e-051813236057966
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

COL4A2 COL7A1

2.70e-052113227856617
Pubmed

E3 ubiquitin ligase FBXW7 balances airway cell fates.

MUC5AC NOTCH4

2.97e-052213234998785
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A2 COL7A1 GPC4

3.45e-0517513328071719
Pubmed

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.

MUC5AC NOTCH4

4.50e-052713221791528
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

MUC5AC NOTCH4

5.21e-052913221402740
Pubmed

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.

COL4A2 COL7A1

6.36e-053213223154389
Pubmed

FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex.

COL4A2 COL7A1

9.48e-053913233580754
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC5AC NOTCH4

1.05e-044113222675208
Pubmed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

COL4A2 COL7A1

2.41e-046213228344315
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

COL4A2 COL7A1

2.57e-046413222261194
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

ZIC5 MFHAS1 PSMC6 GPC4

2.90e-0492213427609421
InteractionHABP2 interactions

COL4A2 F10

4.95e-0518122int:HABP2
InteractionRASL11B interactions

MFHAS1 MUC5AC

5.53e-0519122int:RASL11B
InteractionZFAND5 interactions

MFHAS1 PSMC6

2.14e-0437122int:ZFAND5
InteractionCOL4A1 interactions

COL4A2 COL7A1

3.61e-0448122int:COL4A1
InteractionRITA1 interactions

COL4A2 PSMC6

3.76e-0449122int:RITA1
InteractionCENPO interactions

MFHAS1 FOSB

3.76e-0449122int:CENPO
Cytoband13q34

COL4A2 F10

1.05e-045413213q34
CytobandEnsembl 112 genes in cytogenetic band chr13q34

COL4A2 F10

2.79e-0488132chr13q34
GeneFamilyCollagens

COL4A2 COL7A1

2.81e-0446102490
CoexpressionDI_MARTINO_MATRISOME_HIGHLY_PROLIFERATIVE_HNSCC_TUMOR_CELL_DERIVED

COL4A2 COL7A1

3.08e-0517132M47995
CoexpressionBANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP

COL4A2 GPC4

4.29e-0520132M45002
CoexpressionBANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP

COL4A2 GPC4

4.29e-0520132MM1336
CoexpressionGSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP

COL4A2 MFHAS1 FOSB

5.04e-05150133M8796
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

COL4A2 COL7A1

5.71e-0523132M48001
CoexpressionDI_MARTINO_MATRISOME_HIGHLY_PROLIFERATIVE_HNSCC

COL4A2 COL7A1

7.91e-0527132M47994
CoexpressionNABA_MATRISOME

COL4A2 MUC5AC COL7A1 F10 GPC4

8.28e-051008135MM17056
CoexpressionNABA_MATRISOME

COL4A2 MUC5AC COL7A1 F10 GPC4

9.01e-051026135M5889
CoexpressionGSE34156_UNTREATED_VS_24H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP

MUC5AC SCART1 NOTCH4

1.08e-04194133M8674
CoexpressionGSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_UP

FAM47A COL7A1 GPC4

1.10e-04195133M3566
CoexpressionHALLMARK_COMPLEMENT

COL4A2 F10 NOTCH4

1.18e-04200133M5921
CoexpressionBRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B

COL4A2 COL7A1 FOSB GPC4

1.21e-04554134M2244
CoexpressionNABA_COLLAGENS

COL4A2 COL7A1

2.03e-0443132MM17060
CoexpressionNABA_COLLAGENS

COL4A2 COL7A1

2.12e-0444132M3005
CoexpressionLI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN

COL4A2 GPC4

2.53e-0448132M1246
CoexpressionHAY_BONE_MARROW_STROMAL

COL4A2 COL7A1 FOSB GPC4

4.21e-04767134M39209
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS

MFHAS1 MUC5AC NOTCH4 GPC4

4.62e-04786134M2388
CoexpressionBUSSLINGER_ESOPHAGEAL_QUIESCENT_BASAL_CELLS

COL7A1 FOSB

6.51e-0477132M40001
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS

MFHAS1 MUC5AC NOTCH4 GPC4

6.81e-04871134MM1005
CoexpressionSWEET_KRAS_TARGETS_UP

COL4A2 COL7A1

7.55e-0483132M2448
CoexpressionHU_FETAL_RETINA_FIBROBLAST

COL4A2 FOSB GPC4

8.06e-04385133M39264
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 COL7A1 FOSB GPC4

2.18e-071911342fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MFHAS1 COL7A1 GPC4

7.39e-061351335b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

COL4A2 ZIC5 COL7A1

1.58e-05174133fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A2 COL7A1 GPC4

1.64e-05176133e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A2 COL7A1 GPC4

1.64e-05176133f931192e3cc65414e2245354f443473696cc7ce8
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 FOSB

1.66e-05177133452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL7A1 GPC4

1.75e-0518013340a28b410f46215d6d7cf8a02a18078eb046b5b0
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL7A1 GPC4

1.75e-05180133dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL7A1 GPC4

1.75e-051801330153667e44fdbc3c0d444dcb023069925a2b69a2
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL7A1 GPC4

1.75e-05180133f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MFHAS1 COL7A1 GPC4

1.81e-05182133812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

SCART1 COL7A1 FOSB

1.81e-05182133ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 FOSB GPC4

1.96e-051871336820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCell3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 F10 FOSB

1.96e-05187133150023e6a50c9da461f2321074d2d5e96caafb06
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

COL4A2 MFHAS1 FOSB

2.02e-0518913346e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

COL7A1 FOSB NOTCH4

2.06e-051901334f15842b424eefadbfe451875e517cf70e29607f
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.09e-05191133716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.09e-051911331626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.15e-05193133d75f334fe3d9f39ef02a5de0f8202f7a761a8fc8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 FOSB GPC4

2.15e-05193133ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.15e-0519313341ea268e7697101fe70d8ef1045f3a43b9311739
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.15e-05193133b2abe939027a69b60d83a28d4d4cc53ba1dee4c5
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.15e-0519313387ce81ff5b27d9c4300826d76ff5a62e9c408d5d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.19e-051941333cffb5c58f6d5bd254f39ee9c41b7e1e4da0ff75
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.19e-051941338f19e553f18c313c2a2ff9453884b9484b255d71
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.19e-05194133f95935153bd2c4c3c7b2b729da6f7e98b45fed79
ToppCell3'-Distal_airway-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.19e-05194133f5e3e675187afb6efa774f2a8d685efcf813de82
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 F10 GPC4

2.19e-0519413367fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCelldistal-mesenchymal-Vascular_Smooth_Muscle-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL7A1 F10 GPC4

2.29e-05197133da653dc7d216e202f390e5ab0245f243e3ed213b
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17|GI_small-bowel / Manually curated celltypes from each tissue

MFHAS1 SCART1 FOSB

2.32e-05198133f4fc0cac858fc6dcd779d7959ccec51f78ea8cc2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL7A1 GPC4

2.36e-051991332e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCell(02)_MMP9/10+|World / shred by cell type by condition

COL4A2 COL7A1 GPC4

2.36e-051991333f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCelldistal-mesenchymal-Pericyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.36e-05199133000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCellmedial-mesenchymal-Pericyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-05200133bbda454260016be92b539e220ecf7bcbbc6139e4
ToppCellmedial-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-05200133a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL7A1 GPC4

2.39e-05200133ae91dc047dc80560ba298d8d21a772154fa2775d
ToppCelldistal-mesenchymal-Pericyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-05200133fe31287cfb51d45643bdedbaa5efc03ed87263c6
ToppCellmedial-mesenchymal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-052001334f19e1e40966e27779bf77e8c170ed3ecc24353e
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-05200133911db29f254bb697610e720ba78816e2c7f57933
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 F10 GPC4

2.39e-05200133d70bad979299615fcba707ba21296020918705e6
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 F10 GPC4

2.39e-0520013338c21ec379005f688df33aea65237a063c476c2e
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-05200133867935701fac71a3fe01578362da0676f959736c
ToppCelldistal-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-052001334ee0b2f56c2652435fa78bf6b3c90cea28df74e0
ToppCellmedial-mesenchymal-Pericyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-05200133f36d7cb6345daccebf76997f998e35d959b59452
ToppCellmedial-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 F10 GPC4

2.39e-052001339820fb4f6efcdfc6de937ef2302a98b48426baa3
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR50 MUC5AC

1.31e-0459132439a9d56eeecccd70a4defb430e228329655cb80
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR50 MUC5AC

1.31e-045913250432c7b52fd197e8856ba0296c34cf66a2faaf5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial|GW09 / Sample Type, Dataset, Time_group, and Cell type.

COL4A2 GPC4

2.59e-04831327893ce9fbf34c6250dca9c265fe9b2d4cb889ade
ToppCellMild/Remission-B_naive-13|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SCART1 FOSB

7.54e-0414213249873a2d9b1ae4bdbf253d1c09bf8845cc0cc917
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte|GW09 / Sample Type, Dataset, Time_group, and Cell type.

COL4A2 GPC4

7.54e-0414213285e573616e54d41391b4ad8c3d38e4ca92112673
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like-MAIT|blood / Manually curated celltypes from each tissue

SCART1 COL7A1

7.54e-041421321175d4390d204ffa3a2d2fe24486f85d3b639b72
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL7A1 FOSB

7.65e-0414313228e936c298a45f88d14f0146caf3d5a22d483cd5
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-4|TCGA-Bladder / Sample_Type by Project: Shred V9

F10 FOSB

8.41e-04150132bcb99c6fa81052556ab30f9db5875fccf1ae724b
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL7A1 F10

8.63e-0415213272499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A2 COL7A1

8.74e-0415313265641cc82883716dba0fefb749a30174a63f4da5
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 F10

8.74e-041531320ef7c45cdd854c79e527006034029767f8e108b2
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

SCART1 FOSB

8.97e-0415513283430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FOSB NOTCH4

9.20e-04157132432b8719a8afd289cf48068e12c26a349d753fcc
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 MUC5AC

9.20e-041571322c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SCART1 COL7A1

9.32e-0415813298712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F10 FOSB

9.44e-04159132c9e093d7c1dca83f6546adaf3d874929e2cea612
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

COL4A2 COL7A1

9.44e-041591324f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

COL4A2 NOTCH4

9.55e-04160132958256e3d3836160763b82bb48f794087918d935
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAM47A GPC4

9.55e-04160132f49b0577d8fca58ec2544eeb03b747a6b7fece6e
ToppCellBasal_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

COL7A1 FOSB

9.55e-04160132b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 GPC4

9.67e-0416113282ed45f144a07856fe92d37426c5f92e259a03a9
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MFHAS1 F10

9.79e-0416213264353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MFHAS1 F10

9.91e-041631329f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 NOTCH4

9.91e-04163132977a970b1296234c22178420294cea73506ee02f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 NOTCH4

9.91e-04163132ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 MUC5AC

1.02e-03165132f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FOSB GPC4

1.03e-03166132c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR-_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCART1 FOSB

1.03e-031661329fae71b0a42a9b2222453c03e0a1e83f30117ae9
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic|TCGA-Mesothelium / Sample_Type by Project: Shred V9

COL4A2 GPC4

1.04e-031671329062577a4b7902c9a888d706589d1b05221c0fa8
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

COL4A2 NOTCH4

1.04e-031671325af9127bae05768a5164d5708a4ad37edca99324
ToppCellControl|World / group, cell type (main and fine annotations)

MUC5AC FOSB

1.05e-03168132a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-ILC3|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCART1 FOSB

1.05e-031681324f2f78e14f044b535847bcdbbcec8c0fc8529870
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F10 NOTCH4

1.05e-03168132f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCell3'_v3-Lung-Lymphocytic_Invariant-Inducer-like|Lung / Manually curated celltypes from each tissue

SCART1 FOSB

1.05e-03168132b9bde6f542d730682d34a80e1f7f1609e5c699c7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL7A1 FOSB

1.06e-031691326ff1172da690ca17f7108f1617b255b766971a57
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 COL7A1

1.06e-03169132c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 NOTCH4

1.06e-031691320d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

COL4A2 GPC4

1.08e-03170132d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL7A1 GPC4

1.08e-03170132b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCelldroplet-Fat-Scat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F10 FOSB

1.08e-03170132de722bea7527d6ad11b69f8e9589638f52854beb
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 GPC4

1.08e-031701321f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SCART1 FOSB

1.08e-031701326c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like|bone_marrow / Manually curated celltypes from each tissue

SCART1 FOSB

1.09e-031711322977cffc146470733b5cfd8a1aa80d9346d4804d
ToppCellMyeloid-Myeloid-D_(Mast_cell)|Myeloid / shred on cell class and cell subclass (v4)

FOSB GPC4

1.09e-031711325f1aafc4c55a9c6c3153430186a8a351425a3cb9
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 GPC4

1.09e-031711327c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 COL7A1

1.09e-03171132a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellHealthy/Control-MAIT|World / Disease group and Cell class

SCART1 FOSB

1.09e-0317113261515114b17816a8f9ef6a57262eb9e977b6ede4
ToppCellHealthy_donor-MAIT|World / disease group, cell group and cell class (v2)

SCART1 FOSB

1.10e-031721326524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 GPC4

1.10e-031721320c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 NOTCH4

1.10e-03172132a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

MUC5AC FOSB

1.10e-03172132f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL7A1 FOSB

1.10e-03172132bd73fd3520064d430a153cfdd5c2858b6c184c59
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

COL4A2 NOTCH4

1.10e-03172132c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCellNasal_Brush-Epithelial-Basal_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

COL7A1 NOTCH4

1.10e-031721324483073469001770015526303772fd54906c5d68
ToppCellNasal_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL7A1 NOTCH4

1.10e-0317213258eaadf12366701103a0d1f133462c9495fedc30
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

COL4A2 COL7A1

7.48e-045092GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_2
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

COL4A2 NOTCH4

7.48e-045092GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_ENDO_1
Drug4-oxoretinol

COL4A2 MUC5AC

6.40e-0523122ctd:C041819
Drugalpha-Tocopherol

MUC5AC PSMC6 FOSB

7.70e-05164123ctd:D024502
DrugCamptothecine (S,+) [7689-03-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A

MUC5AC COL7A1 FOSB

1.05e-041821232321_UP
Drugfluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

COL4A2 MUC5AC COL7A1

1.12e-041861235597_UP
Drugestradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A

COL4A2 COL7A1 GPC4

1.31e-04196123373_DN
DrugFurazolidone [67-45-8]; Up 200; 17.8uM; MCF7; HT_HG-U133A

COL4A2 MUC5AC COL7A1

1.37e-041991233358_UP
Druggamma-Tocopherol

MUC5AC FOSB

1.59e-0436122ctd:D024504
DrugSimvastatin

MUC5AC COL7A1 FOSB NOTCH4

1.76e-04581124ctd:D019821
DrugAspirin

COL4A2 PSMC6 COL7A1 FOSB

3.19e-04678124ctd:D001241
Drug1q91

MUC5AC F10

4.28e-0459122CID000448050
DrugMRK 003

ZIC5 MFHAS1 F10 NOTCH4

4.92e-04760124ctd:C523799
Drugapocarotenal

COL4A2 MUC5AC

8.46e-0483122ctd:C004984
DrugAC1L1G2K

F10 FOSB

8.67e-0484122CID000003498
Drugticlopidine

COL7A1 F10

1.30e-03103122CID000005472
Drughydroxylysine

MUC5AC COL7A1

1.45e-03109122CID000001029
DrugAC1L1C2F

MUC5AC COL7A1

1.48e-03110122CID000001711
DrugPPACK

COL7A1 F10

1.56e-03113122CID003036757
Drug4-oxoretinoic acid

COL4A2 MUC5AC

1.61e-03115122ctd:C002202
Drugtyrphostin AG 1478

MUC5AC FOSB

1.81e-03122122ctd:C101044
DrugAC1OCADI

MUC5AC F10

2.06e-03130122CID006914639
Drugdecanoate

PSMC6 COL7A1

2.09e-03131122CID000002969
DrugPCR 4099

COL7A1 F10

2.35e-03139122CID000002806
DiseaseIGFBP-3 measurement

MFHAS1 NOTCH4

2.53e-0454132EFO_0004626
Diseaseinterstitial lung disease

MUC5AC NOTCH4

3.90e-0467132EFO_0004244
Diseaseotosclerosis

COL4A2 MFHAS1

5.69e-0481132EFO_0004213
DiseaseCraniofacial Abnormalities

ZIC5 GPC4

2.08e-03156132C0376634
DiseaseMood Disorders

GPR50 FOSB

2.41e-03168132C0525045

Protein segments in the cluster

PeptideGeneStartEntry
CQCYPEKGGRGQPGP

COL4A2

51

P08572
GCPGGGDKEKCYPPS

MFHAS1

436

Q9Y4C4
KVFQGCGPPKPLPAG

GPC4

336

O75487
YGCIGCKLPQPEYPP

GPR50

11

Q13585
RGLEGCYPKCPPEAP

MUC5AC

1201

P98088
GCKIPYEEGPGPGPL

FOSB

221

P53539
TEPGKYPCGKFCPRP

FAM47A

291

Q5JRC9
PCPVYCPKGQKGEPG

COL7A1

1246

Q02388
GKACIPTGPYPCGKQ

F10

161

P00742
PKGCGPPSPCLYNGS

NOTCH4

1131

Q99466
CGPAVGAPKYVPLPG

SCART1

71

Q4G0T1
PPKGCLLYGPPGTGK

PSMC6

166

P62333
TGEKPFPCPFPGCGK

ZIC5

486

Q96T25