Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontroponin T binding

TNNC1 TNNI2

9.94e-054822GO:0031014
GeneOntologyBiologicalProcessactin filament-based movement

MYH6 MYH9 SLC9A1 AKAP9 SYNE2 TNNC1

3.10e-05153816GO:0030048
GeneOntologyBiologicalProcesscardiac muscle contraction

MYH6 ADRA1B SLC9A1 AKAP9 TNNC1 TNNI2

5.06e-05167816GO:0060048
GeneOntologyCellularComponentciliary basal body

AKAP9 IFT57 ERC1 MLF1 PTPN23 CFAP70 CDC45

1.16e-05195827GO:0036064
GeneOntologyCellularComponentlaminin-5 complex

LAMA5 LAMC2

9.07e-054822GO:0005610
GeneOntologyCellularComponentmicrotubule organizing center

AKAP9 IFT57 RNF19A ERC1 DYNLL2 MLF1 PTPN23 CFAP70 CNTLN NEK9 CCDC116 CDC45

2.36e-049198212GO:0005815
GeneOntologyCellularComponentactin cytoskeleton

MYH6 MYH9 PVALB SPTBN2 DYNLL2 TNNC1 ATP12A TNNI2 LCP1

4.22e-04576829GO:0015629
GeneOntologyCellularComponenttroponin complex

TNNC1 TNNI2

5.38e-049822GO:0005861
GeneOntologyCellularComponentcell cortex

MYH9 ERC1 PVALB SPTBN2 EXOC6B LAMC2 TRAK1

6.36e-04371827GO:0005938
GeneOntologyCellularComponentlaminin complex

LAMA5 LAMC2

6.70e-0410822GO:0043256
GeneOntologyCellularComponentcilium

AKAP4 AKAP9 IFT57 GUCY2F ERC1 RP1L1 DYNLL2 MLF1 PTPN23 CFAP70 CDC45

7.45e-048988211GO:0005929
GeneOntologyCellularComponentnon-motile cilium

IFT57 GUCY2F RP1L1 DYNLL2 MLF1

1.05e-03196825GO:0097730
GeneOntologyCellularComponentmyosin complex

MYH6 MYH9 DYNLL2

1.61e-0359823GO:0016459
GeneOntologyCellularComponentcortical cytoskeleton

MYH9 ERC1 PVALB SPTBN2

1.67e-03129824GO:0030863
DomainCRAL_TRIO_N

SEC14L3 SEC14L4 SEC14L2

1.17e-0511793PF03765
DomainCRAL-bd_toc_tran

SEC14L3 SEC14L4 SEC14L2

1.56e-0512793IPR001071
DomainCRAL_TRIO_N

SEC14L3 SEC14L4 SEC14L2

1.56e-0512793SM01100
DomainEMP24_GP25L

SEC14L3 SEC14L4 SEC14L2

3.19e-0515793PF01105
DomainCRAL/TRIO_N_dom

SEC14L3 SEC14L4 SEC14L2

3.19e-0515793IPR011074
DomainGOLD_dom

SEC14L3 SEC14L4 SEC14L2

6.72e-0519793IPR009038
DomainGOLD

SEC14L3 SEC14L4 SEC14L2

6.72e-0519793PS50866
DomainCRAL_TRIO

SEC14L3 SEC14L4 SEC14L2

9.17e-0521793PF00650
DomainActinin_actin-bd_CS

SPTBN2 SYNE2 LCP1

1.21e-0423793IPR001589
Domain-

SEC14L3 SEC14L4 SEC14L2

1.21e-04237933.40.525.10
DomainACTININ_2

SPTBN2 SYNE2 LCP1

1.21e-0423793PS00020
DomainACTININ_1

SPTBN2 SYNE2 LCP1

1.21e-0423793PS00019
DomainSEC14

SEC14L3 SEC14L4 SEC14L2

1.57e-0425793SM00516
DomainCRAL_TRIO

SEC14L3 SEC14L4 SEC14L2

1.98e-0427793PS50191
DomainCRAL-TRIO_dom

SEC14L3 SEC14L4 SEC14L2

2.21e-0428793IPR001251
DomainLAMININ_IVA

LAMA5 LAMC2

4.87e-048792PS51115
DomainLaminin_B

LAMA5 LAMC2

4.87e-048792PF00052
DomainLamB

LAMA5 LAMC2

4.87e-048792SM00281
DomainLaminin_IV

LAMA5 LAMC2

4.87e-048792IPR000034
DomainMyosin_N

MYH6 MYH9

1.79e-0315792PF02736
DomainMyosin_N

MYH6 MYH9

1.79e-0315792IPR004009
DomainTumour_necrosis_fac-like_dom

SEC14L3 SEC14L4 SEC14L2

1.90e-0358793IPR008983
DomainMyosin_tail_1

MYH6 MYH9

2.59e-0318792PF01576
DomainMyosin_tail

MYH6 MYH9

2.59e-0318792IPR002928
DomainCH

SPTBN2 SYNE2 LCP1

2.63e-0365793SM00033
DomainMyosin-like_IQ_dom

MYH6 MYH9

2.88e-0319792IPR027401
Domain-

MYH6 MYH9

2.88e-03197924.10.270.10
DomainRCC1

MYCBP2 NEK9

3.19e-0320792PF00415
DomainCH

SPTBN2 SYNE2 LCP1

3.25e-0370793PF00307
Domain-

SPTBN2 SYNE2 LCP1

3.39e-03717931.10.418.10
DomainRCC1_1

MYCBP2 NEK9

3.52e-0321792PS00625
DomainRCC1_2

MYCBP2 NEK9

3.52e-0321792PS00626
DomainRCC1_3

MYCBP2 NEK9

3.52e-0321792PS50012
DomainCH

SPTBN2 SYNE2 LCP1

3.66e-0373793PS50021
DomainTPR-contain_dom

SUGT1 NASP PTPN23 CFAP70

3.77e-03150794IPR013026
DomainReg_chr_condens

MYCBP2 NEK9

3.86e-0322792IPR000408
Domain-

MYCBP2 NEK9

3.86e-03227922.130.10.30
DomainEF-hand_1

PVALB TESC TNNC1 LCP1

3.95e-03152794PF00036
DomainCH-domain

SPTBN2 SYNE2 LCP1

3.95e-0375793IPR001715
DomainSpectrin

SPTBN2 SYNE2

4.22e-0323792PF00435
DomainRCC1/BLIP-II

MYCBP2 NEK9

4.22e-0323792IPR009091
DomainEFh

PVALB TESC TNNC1 LCP1

4.53e-03158794SM00054
DomaintRNA-bd_arm

CNTLN TRAK1

4.59e-0324792IPR010978
DomainMetalloPept_cat_dom

THOP1 ADAM32 MMP14

4.90e-0381793IPR024079
Domain-

THOP1 ADAM32 MMP14

4.90e-03817933.40.390.10
DomainTPR_REGION

SUGT1 NASP PTPN23 CFAP70

5.28e-03165794PS50293
DomainTPR

SUGT1 NASP PTPN23 CFAP70

5.28e-03165794PS50005
DomainEF-hand_7

PVALB TNNC1 LCP1

5.61e-0385793PF13499
DomainEF_Hand_1_Ca_BS

PVALB TESC TNNC1 LCP1

6.48e-03175794IPR018247
DomainZnF_U1

ZFHX4 TUT7

6.66e-0329792SM00451
DomainZnf_U1

ZFHX4 TUT7

6.66e-0329792IPR003604
DomainSpectrin_repeat

SPTBN2 SYNE2

6.66e-0329792IPR002017
DomainEGF_LAM_2

LAMA5 LAMC2

7.12e-0330792PS50027
DomainEGF_LAM_1

LAMA5 LAMC2

7.12e-0330792PS01248
DomainSpectrin/alpha-actinin

SPTBN2 SYNE2

8.07e-0332792IPR018159
DomainSPEC

SPTBN2 SYNE2

8.07e-0332792SM00150
Pubmed

Rat supernatant protein factor-like protein stimulates squalene monooxygenase and is activated by protein kinase A.

SEC14L3 SEC14L4 SEC14L2

1.26e-08382315033454
Pubmed

Cloning of novel human SEC14p-like proteins: ligand binding and functional properties.

SEC14L3 SEC14L4 SEC14L2

5.04e-08482312757856
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ZC3H14 SUGT1 MYCBP2 ERC1 SPTBN2 NASP PTPN23 NEK9 SNRNP200 PPP6R3

6.84e-07549821038280479
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

ZC3H14 ARFGAP2 MYH9 SUGT1 ERC1 SYNE2 NASP LAMA5 PTPN23 VPS26A SNRNP200

1.60e-06754821135906200
Pubmed

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.

MYH6 MYH9 SPTBN2 LAMA5 ITIH3

2.70e-069282537343697
Pubmed

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.

MYH9 SETX DYNLL2 EIF3C TNNC1 SNRNP200 SYNCRIP

2.77e-0625982731162944
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZC3H14 MYH9 MYCBP2 TUT7 SPTBN2 SYNE2 LCP1 SNRNP200 PPP6R3 SYNCRIP

3.23e-06653821022586326
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

ARFGAP2 SUGT1 ERC1 TUT7 SPTBN2 DYNLL2 MLF1 PTPN23 CNTLN LCP1 PPP6R3

5.20e-06853821128718761
Pubmed

NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP.

SLC9A1 MMP14

5.49e-06282221669197
Pubmed

Controlled release systems containing solid dispersions: strategies and mechanisms.

SLC9A1 TESC

5.49e-06282221553168
Pubmed

Relation between laminin-5 gamma 2 chain and cell surface metalloproteinase MT1-MMP in clear cell carcinoma of the ovary.

LAMC2 MMP14

5.49e-06282219047908
Pubmed

Human homolog of mouse tescalcin associates with Na(+)/H(+) exchanger type-1.

SLC9A1 TESC

5.49e-06282211696366
Pubmed

Conformation of the critical pH sensitive region of troponin depends upon a single residue in troponin I.

TNNC1 TNNI2

5.49e-06282224333682
Pubmed

NHE1 mediates migration and invasion of HeLa cells via regulating the expression and localization of MT1-MMP.

SLC9A1 MMP14

5.49e-06282221997166
Pubmed

N-myristoylation and Ca2+ binding of calcineurin B homologous protein CHP3 are required to enhance Na+/H+ exchanger NHE1 half-life and activity at the plasma membrane.

SLC9A1 TESC

5.49e-06282222984264
Pubmed

Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.

PVALB TNNC1 TNNI2

5.63e-061582324852826
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

AKAP9 SUGT1 MYCBP2 IFT57 ERC1 SPTBN2 SYNE2 KCTD3 NUCKS1 PTPN23 EIF3C PPP6R3

6.33e-061049821227880917
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

MYH9 THOP1 SUGT1 NUCKS1 NASP IREB2 PTPN23 PSMD9 EIF3C VPS26A NEK9 SNRNP200 PPP6R3 SYNCRIP

7.23e-061455821422863883
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZC3H14 MYH9 SUGT1 ERC1 NUCKS1 NASP PTPN23 EIF3C NEK9 SNRNP200 PPP6R3

1.22e-05934821133916271
Pubmed

The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.

MYH6 PVALB TNNC1 TNNI2

1.35e-056182427166947
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYH9 SETX SUGT1 MYCBP2 TUT7 PTPN23 VPS26A SRBD1 MMP14 NEK9 SNRNP200 SYNCRIP CDC45

1.62e-051353821329467282
Pubmed

Calcineurin B homologous protein 3 binds with high affinity to the CHP binding domain of the human sodium/proton exchanger NHE1.

SLC9A1 TESC

1.64e-05382230287853
Pubmed

The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling.

SEC14L3 SEC14L2

1.64e-05382228463110
Pubmed

LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration.

SYNE2 MMP14

1.64e-05382229934494
Pubmed

The Na+/H+ exchanger cytoplasmic tail: structure, function, and interactions with tescalcin.

SLC9A1 TESC

1.64e-05382212809501
Pubmed

NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA.

MYH9 NEK9

1.64e-05382234078910
Pubmed

Identification and mutagenesis of a highly conserved domain in troponin T responsible for troponin I binding: potential role for coiled coil interaction.

TNNC1 TNNI2

1.64e-0538229448267
Pubmed

Gamma oscillation plasticity is mediated via parvalbumin interneurons.

PVALB GRM5

1.64e-05382238295164
Pubmed

Proton-magnetic-resonance studies on the interaction of rabbit skeletal-muscle troponin I with troponin C and actin.

TNNC1 TNNI2

1.64e-0538227103951
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

THOP1 KCTD3 PTPN23 EIF3C VPS26A LCP1 MMP14 SNRNP200 PPP6R3 SYNCRIP CDC45

1.79e-05974821128675297
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

MYH9 SETX SUGT1 ERC1 NUCKS1 NASP EIF3C PPP6R3

2.53e-0550382816964243
Pubmed

Localization of laminin-5, HD1/plectin, and BP230 in the submandibular glands of developing and adult mice.

LAMA5 LAMC2

3.28e-05482210651091
Pubmed

Cloning and developmental expression of nonmuscle myosin IIA (Myh9) in the mammalian inner ear.

MYH6 MYH9

3.28e-05482215079858
Pubmed

Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis.

SEC14L4 SEC14L2

3.28e-05482217077281
Pubmed

Calcium affects CHP1 and CHP2 conformation and their interaction with sodium/proton exchanger 1.

SLC9A1 TESC

3.28e-05482231912575
Pubmed

Contractile protein mutations and heart disease.

MYH6 TNNC1

3.28e-0548228791411
Pubmed

Changes in expression of nonmuscle myosin heavy chain isoforms during muscle and nonmuscle tissue development.

MYH6 MYH9

3.28e-0548228482409
Pubmed

Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration.

LAMA5 MMP14

3.28e-05482215967115
Pubmed

Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons.

PVALB GRM5

3.28e-05482235045338
Pubmed

Cholinergic Neurons of the Medial Septum Are Crucial for Sensorimotor Gating.

PVALB GRM5

3.28e-05482231028115
Pubmed

Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma.

LAMC2 MMP14

3.28e-05482215743799
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

MYH9 MYCBP2 KCTD3 SNRNP200

5.03e-058582416051665
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

EDEM3 MYH9 THOP1 SETX SUGT1 MYCBP2 SYNE2 LAMA5 PTPN23 PSMD9 PPP6R3 SYNCRIP

5.11e-051297821233545068
Pubmed

Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.

MYH6 TNNC1 TNNI2

5.41e-053182321985497
Pubmed

The lipid-binding SEC14 domain.

SEC14L3 SEC14L2

5.47e-05582217428729
Pubmed

Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts.

LAMA5 LAMC2

5.47e-0558229719032
Pubmed

Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution.

TNNC1 TNNI2

5.47e-0558229560191
Pubmed

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system.

TNNC1 TNNI2

5.47e-0558228987992
Pubmed

Coding sequence rare variants identified in MYBPC3, MYH6, TPM1, TNNC1, and TNNI3 from 312 patients with familial or idiopathic dilated cardiomyopathy.

MYH6 TNNC1

5.47e-05582220215591
Pubmed

The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.

MYH6 TNNC1 TNNI2

5.96e-053282323369715
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

PANK2 MYCBP2 IFT57 ERC1 KCTD3 DYNLL2 EXOC6B MLF1 PSMD9 NEK9 SNRNP200 SYNCRIP

6.10e-051321821227173435
Pubmed

Hereditary Ataxia Overview

SLC9A1 SETX ATN1 SPTBN2

6.85e-059282420301317
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

EDEM3 MYH9 AKAP9 MYCBP2 ERC1 TUT7 PSMD9 EIF3C NEK9

7.21e-0575482933060197
Pubmed

The DNA sequence of human chromosome 22.

SEC14L3 MYH9 PVALB POTEH SEC14L4 SEC14L2

7.92e-0530082610591208
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

MYH9 MYCBP2 ERC1 SPTBN2 NUCKS1 NASP PSMD9 LCP1 NEK9 SNRNP200 SYNCRIP

8.00e-051149821135446349
Pubmed

Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice.

TNNC1 TNNI2

8.19e-0568227958896
Pubmed

Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation.

LAMC2 MMP14

8.19e-05682215572153
Pubmed

ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.

MYH9 SPTBN2

8.19e-05682237069398
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYH9 TRIM67 AKAP9 MYCBP2 ERC1 SPTBN2 SYNE2 KCNJ16 GRM5 NEK9

8.92e-05963821028671696
Pubmed

Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation.

MYH9 SETX NEK9

9.26e-053782323180766
Pubmed

The matrix metalloproteinase-14 (MMP-14) gene is structurally distinct from other MMP genes and is co-expressed with the TIMP-2 gene during mouse embryogenesis.

MYH6 MMP14

1.14e-0478229325265
Pubmed

Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.

MYH6 MYH9

1.14e-04782221126233
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

TUT7 LAMC2 EIF3C SRBD1 SNRNP200 SYNCRIP POLR3C

1.23e-0446982737314180
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

ZC3H14 MYH9 SPTBN2 KCTD3 EIF3C SNRNP200 SYNCRIP

1.37e-0447782731300519
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH6 MYH9 TRIM67 ERC1 SPTBN2 SYNE2 DYNLL2 SRBD1 ATP12A LCP1 SYNCRIP CCDC148

1.39e-041442821235575683
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

MYH9 SPTBN2 NUCKS1 EIF3C SNRNP200 SYNCRIP

1.42e-0433482630425250
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

SUGT1 MYCBP2 ERC1 DYNLL2 NASP SRBD1 LCP1 NEK9

1.43e-0464582825281560
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMA5 LAMC2

1.52e-0488229489770
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA5 LAMC2

1.52e-0488228872465
Pubmed

Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.

LAMA5 LAMC2

1.52e-04882223529140
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

MYH9 ERC1 SPTBN2 DYNLL2 NUCKS1 NASP EIF3C LCP1 SNRNP200

1.73e-0484782935235311
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP9 MYCBP2 SYNE2 MLF1 NUCKS1 EIF3C NEK9

1.76e-0449782723414517
Pubmed

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

MYH9 EIF3C SRBD1 SNRNP200 SYNCRIP

1.89e-0422382520020773
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARFGAP2 PANK2 SETX AKAP9 MYCBP2 ERC1 SYNE2 NEK9 TRAK1

1.95e-0486182936931259
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

MYH9 NUCKS1 NASP LAMC2 LCP1 NEK9 SNRNP200

1.96e-0450682730890647
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYCBP2 ERC1 SYNE2 PTPN23 SNRNP200

1.97e-0422582512168954
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

ZC3H14 MYH9 PANK2 MYCBP2 ERC1 SYNE2

2.07e-0435882632460013
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

MYH9 PANK2 MYCBP2 ERC1 UBAC1 DYNLL2 NASP GSKIP NEK9 SNRNP200 SYNCRIP

2.11e-041284821117353931
Pubmed

Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.

PVALB TNNC1 TNNI2

2.29e-045082327597886
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA5 LAMC2

2.44e-04108229034910
Pubmed

Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area.

PVALB SLC16A10

2.44e-041082229377458
Pubmed

Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.

LAMA5 LAMC2

2.44e-041082211784026
Pubmed

Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.

LAMA5 LAMC2

2.44e-041082215623520
Pubmed

Functional cooperation between FACT and MCM helicase facilitates initiation of chromatin DNA replication.

NEK9 CDC45

2.44e-041082216902406
Pubmed

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.

PANK2 TUT7 PPP6R3

2.87e-045482326288249
Pubmed

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.

LAMA5 LAMC2

2.98e-04118228707838
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA5 LAMC2

2.98e-041182221524702
Pubmed

The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes.

AKAP9 TNNI2

2.98e-041182236627242
Pubmed

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.

LAMA5 LAMC2

2.98e-041182223472759
Pubmed

The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons.

MYH6 PVALB

2.98e-041182220739404
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

MYH9 SPTBN2 EIF3C SRBD1 NEK9 SNRNP200 SYNCRIP

3.29e-0455182734728620
Pubmed

Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.

MYH9 NASP NEK9

3.37e-045782338223760
Pubmed

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression.

PVALB MLF1 TNNI2

3.55e-045882321884692
Pubmed

Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).

SLC9A1 SPTBN2

3.57e-041282221705333
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMA5 LAMC2

3.57e-04128229396756
Pubmed

Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.

MYH6 MYH9

3.57e-04128228424456
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

MYH9 SUGT1 NUCKS1 NASP SNRNP200

3.57e-0425682533397691
Pubmed

Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.

LAMA5 LAMC2

4.21e-04138229670011
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

MYH9 TUT7 DYNLL2 NASP LCP1 SYNCRIP

4.31e-0441182636652389
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

FHAD1 ABCA5 LAMA5

4.53e-046382311572484
InteractionSEC14L3 interactions

SEC14L3 SEC14L4 SEC14L2

1.24e-066813int:SEC14L3
InteractionACTR1A interactions

ARFGAP2 MYH9 TRIM67 SUGT1 SPTBN2 DYNLL2 NASP CDC45

1.44e-05274818int:ACTR1A
InteractionEML4 interactions

MYH9 TRIM67 DYNLL2 NASP NEK9 PPP6R3

1.89e-05137816int:EML4
InteractionCRLF3 interactions

TRIM67 SUGT1 ERC1 VPS26A

1.98e-0540814int:CRLF3
InteractionRCOR1 interactions

MYH9 TRIM67 ZFHX4 MYCBP2 ERC1 DYNLL2 NUCKS1 PSMD9 NEK9 PPP6R3

2.83e-054948110int:RCOR1
InteractionHSF1 interactions

ZC3H14 ARFGAP2 SETX TRIM67 SUGT1 ERC1 SYNE2 PTPN23 VPS26A SNRNP200 SYNCRIP

3.12e-056098111int:HSF1
CytobandEnsembl 112 genes in cytogenetic band chr22q12

SEC14L3 MYH9 PVALB SEC14L4 SEC14L2

6.67e-05235825chr22q12
Cytoband22q12.2

SEC14L3 SEC14L4 SEC14L2

1.58e-045882322q12.2
Cytoband17q24.3

ABCA5 KCNJ16

4.21e-041782217q24.3
CytobandXq22

GUCY2F BEX1

7.11e-0422822Xq22
Cytoband13q14.3

SUGT1 LCP1

2.47e-034182213q14.3
Cytoband3p21.1

TNNC1 ITIH3

2.59e-03428223p21.1
GeneFamilySEC14 family|PRELI domain containing

SEC14L3 SEC14L4 SEC14L2

5.01e-0765431063
GeneFamilyEF-hand domain containing|Troponin complex subunits

TNNC1 TNNI2

2.42e-0485421219
GeneFamilyLaminin subunits

LAMA5 LAMC2

5.67e-0412542626
GeneFamilyMyosin heavy chains

MYH6 MYH9

8.97e-04155421098
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP4 AKAP9

3.38e-0329542396
GeneFamilyEF-hand domain containing

PVALB TESC TNNC1 LCP1

4.13e-03219544863
ToppCellVE|World / Condition, Cell_class and T cell subcluster

MYH9 SETX MYCBP2 RNF19A SYNE2 NASP LCP1

8.85e-082008278ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellfacs-Heart-RV-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINA11 MYH6 MLF1 TESC TNNC1 SEC14L4

4.79e-071588262ef43d14ee65d004dc62c12ff209bbe12e4db681
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADRA1B RNF19A MLF1 LAMC2 TESC CCL23

8.71e-071758268a37b2811f39bb9baa537e8755a29d559eb8185a
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

SYNE2 KCNJ16 LAMC2 CFAP70 CCDC148

1.03e-0515682510d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 CFAP70 GRM5 SEC14L4 CCDC148

1.52e-0516982514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 SLC9A1 NASP LAMC2 PSMD9

1.80e-05175825711ace94fa9a763c6ae48171a690953f25deebe4
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 ADRA1B MLF1 TESC TNNC1

1.90e-05177825692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 ADRA1B MLF1 TESC TNNC1

1.90e-05177825c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADRA1B MLF1 LAMC2 TESC CCL23

1.95e-05178825a95bb77a2c2ce7c38989e6f971812f7ee9f5bd4b
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1|TCGA-Liver / Sample_Type by Project: Shred V9

SLC9A1 KCNJ16 LAMC2 ICA1L CCDC148

1.95e-0517882551c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 TRIM67 PVALB MLF1 TNNC1

2.12e-0518182509a574a3257e25c8b05a2ab20623a6b07331411a
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 TRIM67 PVALB MLF1 TNNC1

2.12e-05181825ac4142aa93706b7067f63d2d38e2456859e60768
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 ADRA1B MLF1 TNNC1 TNNI2

2.23e-05183825905e1e9be0f15be184447df04b134a6aa8279074
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 ADRA1B MLF1 TNNC1 TNNI2

2.23e-0518382592eed783347a372b850de3189e72525082390014
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA5 PVALB KCNJ16 TNNC1 HMGCLL1

2.23e-051838252f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

FHAD1 MYH9 TUT7 SYNE2 LCP1

2.29e-05184825791f1bcb954aadc63d4117c400537d036f68734d
ToppCellP15-Epithelial-airway_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEC14L3 FHAD1 MYH6 MLF1 CFAP70

2.54e-05188825e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 FHAD1 MLF1 CFAP70 CCDC148

2.60e-0518982538cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEX1 UBAC1 PVALB MLF1 TNNI2

2.60e-05189825d2b008f98739c6af7ee63b643011a240db20e4d8
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA5 IFT57 RNF19A SYNE2 NEK9

3.02e-05195825ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 RNF19A SYNE2 DYNLL2 LCP1

3.10e-05196825ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellAT1|World / shred by cell class for parenchyma

LAMA5 LAMC2 TNS4 TNNC1 CDC45

3.10e-051968252bc487f8a109a6961ebff111dec79c2227ea60ac
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEC14L3 FHAD1 AKAP9 MLF1 CFAP70

3.18e-0519782591637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEC14L3 FHAD1 AKAP9 MLF1 CFAP70

3.18e-0519782522c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 AKAP9 SYNE2 CFAP70 TNNI2

3.18e-0519782574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

AKAP9 ABCA5 IFT57 SYNE2 CFAP70

3.18e-05197825272c7f4e582ef57564450540242b0db766b78328
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEC14L3 FHAD1 AKAP9 MLF1 CFAP70

3.18e-051978253bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEC14L3 FHAD1 AKAP9 MLF1 CFAP70

3.18e-0519782587db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

AKAP9 SYNE2 LAMA5 LAMC2 TNS4

3.25e-05198825f5b7013045b61fc56894f80092f799770dde1c8f
ToppCellEpithelial_cells-AT1-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MYH9 LAMA5 LAMC2 TNNC1 MMP14

3.25e-05198825fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

FHAD1 SETX AKAP9 RNF19A SYNE2

3.33e-0519982561b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(4)_Endothelial_cells-(4)_Blood_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MYH9 LAMA5 TESC CCL23 LCN6

3.33e-05199825e24d70e79f25cdd3300bf5e2322713355264d4c5
ToppCellASK452-Epithelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

FHAD1 IFT57 MLF1 LAMC2 CFAP70

3.33e-05199825e8778d4d2bc7e15b4c7989a93e5808a76738df46
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

ZFHX4 SYNE2 NASP CNTLN CDC45

3.41e-052008254923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellsevere|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYH9 RNF19A SYNE2 NUCKS1 LCP1

3.41e-05200825accc618d6b960bff30cb531c1226295bfc8650f6
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

MYH9 SETX SYNE2 EIF3C LCP1

3.41e-052008252281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

ZFHX4 SYNE2 NASP CNTLN CDC45

3.41e-05200825dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellCOVID-19|World / Disease, condition lineage and cell class

MYH9 MYCBP2 RNF19A SYNE2 LCP1

3.41e-052008257dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Ptrf|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX4 TESC LCN6 SEC14L2

1.07e-04133824a1bc34e5dda4ff4716b857931cc196f6770f58f4
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

AKAP9 RNF19A SYNE2 CCDC116

1.13e-04135824ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|E18.5-samps / Age Group, Lineage, Cell class and subclass

SEC14L3 LAMA5 LAMC2 TRAK1

1.37e-0414282477fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

EDEM3 TUT7 LAMA5 EIF3C

1.49e-04145824fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNS4 TNNI2 LCP1 ICA1L

1.78e-0415282427718e92715ddc80f28b457a5d6d6a3ac2b205d2
ToppCellfrontal_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

FHAD1 ADRA1B ZFHX4 TNNC1

1.78e-04152824f9c29d4568402ca07a717dbffb3ccc7f35c5fe56
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

ABCA5 UBAC1 TNNI2 SLC16A10

1.92e-04155824d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYH9 SETX TUT7 EIF3C

1.92e-041558240a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFHX4 BEX1 DYNLL2 NASP

1.97e-04156824b28bbdb515317368f1231b0b15d7442352f3b400
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA5 KCNJ16 HMGCLL1 CCDC148

1.97e-041568244d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 TRIM67 MLF1 TNNC1

2.02e-041578249021900d9b1a71210c9c414a9d165eaf399eb607
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 TRIM67 MLF1 TNNC1

2.02e-04157824c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA5 KCNJ16 HMGCLL1 TRAK1

2.07e-041588247960337d87afecf2692ab65e5991f052ceddfacc
ToppCellcontrol-Epithelial-Ciliated-diff|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FHAD1 IFT57 MLF1 SEC14L4

2.22e-04161824ef4b946914a4e2727ed57362dc6965c299520f35
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA5 PVALB KCNJ16 TNNC1

2.28e-0416282436ddebe3bb172c992739353b7b049b2dde98b559
ToppCell11.5-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

SEC14L3 UBAC1 CFAP70 SEC14L4

2.33e-04163824e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCell11.5-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

SEC14L3 UBAC1 CFAP70 SEC14L4

2.33e-0416382431b60e065bac4ad380247964e7574f210106ebae
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP4 ATN1 HMGCLL1 CCDC116

2.44e-041658240edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP4 ATN1 HMGCLL1 CCDC116

2.44e-04165824fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 ABCA5 LAMC2 ADAM32

2.50e-0416682411b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

ERC1 PTPN23 CFAP70 TRAK1

2.50e-0416682432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellfacs-BAT-Fat-24m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 AKAP4 MLF1 TNNC1

2.50e-04166824001a31aaa4ab4d5606b894faf6fcaad524405064
ToppCellfacs-BAT-Fat-24m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 AKAP4 MLF1 TNNC1

2.50e-0416682431ed1290b4a977eabfc29674a5c593985bff6a74
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 ABCA5 LAMC2 ADAM32

2.50e-04166824fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellfacs-BAT-Fat-24m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 AKAP4 MLF1 TNNC1

2.50e-04166824c71ad3fc6a14507609d17756431d3deff9fda418
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

SEC14L3 FHAD1 MLF1 CFAP70

2.56e-0416782426cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 ABCA5 LAMC2 ADAM32

2.56e-04167824bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 ABCA5 LAMC2 ADAM32

2.56e-041678249f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 FHAD1 MLF1 CFAP70

2.61e-04168824fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 FHAD1 MLF1 CFAP70

2.61e-041688247edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF19 BEX1 TESC TNNC1

2.61e-0416882408f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 KCNJ16 CFAP70 CCDC148

2.67e-041698248bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TESC CCL23 ITIH3 CCDC148

2.67e-04169824a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCellcontrol-Epithelial-Ciliated-diff|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FHAD1 IFT57 MLF1 SEC14L4

2.74e-04170824334c4103eb6e021766f5638a4ab14b59ad085ac7
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DYNLL2 TNNI2 CCDC116 CDC45

2.80e-041718241efce222989460bb59bd9fa955e7d9a60c73994c
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYH9 SETX TUT7 EIF3C

2.80e-04171824d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 FHAD1 MLF1 CFAP70

2.80e-041718244f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PVALB TMIGD3 CCL23 CCDC148

2.92e-04173824b9dc42d629d13e63aada5ae49ba0cbb0952c5fe9
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIM67 ZFHX4 IFT57 CCDC148

2.99e-04174824742c73c9e090848b464323cb17579b86658c6792
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SEC14L3 FHAD1 MLF1 CFAP70

2.99e-04174824f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIM67 ZFHX4 IFT57 CCDC148

2.99e-041748247fed9722e64c60843092f2ba71256e3043011ef6
ToppCelldroplet-Heart-4Chambers-21m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 ADRA1B DYNLL2 TNNC1

2.99e-04174824f098778ea74012861ec74b425e45776a31f67679
ToppCellwk_15-18-Hematologic-Myeloid-Promyelocyte-like|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TESC TNNI2 CCL23 LCP1

2.99e-041748241c0c04c37bfdbdb47bda57784734e0c5f1e8ed87
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

PVALB TNNI2 CCL23 LCP1

3.05e-041758241cf99de391552d4f8dbe2ed5b01fc3b8adca61b6
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SEC14L3 FHAD1 MLF1 CFAP70

3.05e-04175824c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGAP2 IFT57 TNNC1 TNNI2

3.12e-041768246b4afd2c9268172063fe5832896bea15e862579e
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 LAMC2 TNNC1 HMGCLL1

3.12e-04176824458720776b0151cd55acc352d509599cb62f0ca8
ToppCellASK452-Epithelial-Secretory|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

EDEM3 TNS4 SRBD1 ATP12A

3.12e-04176824dd334c8a8a31dc26b2d558df0ef6bed6dc1a6610
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 SERPINA11 FHAD1 CCDC148

3.19e-041778243cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC14L3 SERPINA11 FHAD1 CCDC148

3.19e-0417782412a52a12a87a31e501ced611f46a90d172ca7e35
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBAC1 PVALB MLF1 TNNI2

3.19e-04177824f6ff1b035fa2418f2448c99d81faa927ece93dfa
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBAC1 PVALB MLF1 TNNI2

3.26e-0417882469f68eeab11b088fcb1f963c92eff0f1cd0e711a
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 LAMC2 SEC14L4 HMGCLL1

3.33e-0417982488dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 LAMC2 SEC14L4 HMGCLL1

3.33e-04179824daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PVALB SPTBN2 TESC HMGCLL1

3.40e-04180824fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEX1 PVALB MLF1 TNNI2

3.40e-04180824cea62fc006d68c3815c88bf17ec2617d7e41c3d2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 SPTBN2 TRAK1 SLC16A10

3.40e-04180824023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PVALB SPTBN2 TESC HMGCLL1

3.40e-041808246763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCellP03-Epithelial-airway_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEC14L3 FHAD1 MLF1 CFAP70

3.47e-041818241ea21d860d4d7abab3e21e130a16d044006656ee
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 SPTBN2 KCNJ16 SLC16A10

3.47e-04181824aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Red_blood_cells-RBC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEC14L3 UBAC1 TESC SEC14L4

3.47e-04181824f4cd6dba4c04c5cb550f44468eb29c07238fbda4
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADRA1B TESC CCL23 ITIH3

3.47e-041818244d7d367f4ed390908888391335c714a22b5a75c4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

MYH9 SETX AKAP9 SYNE2

1.02e-0449544GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Diseasecalcineurin B homologous protein 1 measurement

SLC9A1 TESC

2.12e-053792EFO_0802353
DiseaseHypertrophic Cardiomyopathy

MYH6 SLC9A1 TNNC1

4.87e-0457793C0007194
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH6 TNNI2

7.27e-0415792DOID:0050646 (implicated_via_orthology)
Diseasenon-melanoma skin carcinoma

SEC14L3 ZFHX4 RNF19A GUCY2F GRM5

7.38e-04265795EFO_0009260
DiseaseHypertriglyceridemia

LAMC2 LCP1

1.18e-0319792EFO_0004211
DiseasePrimary familial hypertrophic cardiomyopathy

MYH6 TNNC1

1.58e-0322792cv:C0949658
Diseasepsoriatic arthritis

SEC14L3 CCDC116 SLC16A10

1.67e-0387793EFO_0003778
DiseaseHypertrophic obstructive cardiomyopathy

MYH6 SLC9A1

2.04e-0325792C4551472
Diseaseage at assessment, lateral ventricle volume change measurement

RNF19A LCP1

2.38e-0327792EFO_0008007, EFO_0021502
Diseasealpha fetoprotein measurement

SERPINA11 SETX NASP

2.48e-03100793EFO_0010583

Protein segments in the cluster

PeptideGeneStartEntry
VKGMSASDMKEVISR

ABCA5

1401

Q8WWZ7
EEMKTRHKGEMENAL

AKAP9

461

Q99996
ARVTKDAETEFMMSK

CCL23

21

P55773
EKATERMAAMKTEAG

CCDC116

91

Q8IYX3
DTMASKARMGIEIEE

CCDC148

511

Q8NFR7
SADRAKSEMATMKVR

CNTLN

801

Q9NXG0
MESKEKRAVNSLSME

BEX1

1

Q9HBH7
EFSTMKAEMKERDKG

AKAP4

466

Q5JQC9
NKDSMSMRSGRKKEA

ATN1

6

P54259
NLEAGVMKEMSNSKE

ADRA1B

236

P35368
EDMGSIMERASGKTE

ADAM32

666

Q8TC27
DAKKQAEESMVASMR

ARFGAP2

261

Q8N6H7
VTGKADADTMKAMRR

MMP14

76

P50281
MKDSKISSMERGLRD

ERC1

386

Q8IUD2
MVDFAAMREAVKTLG

IREB2

96

P48200
MDKRVSEEGMKVSCT

PTPN23

131

Q9H3S7
EGKASGMEARSVEMS

ARHGEF19

231

Q8IW93
ASKAASKQREMLMED

NUCKS1

96

Q9H1E3
SGMEAFKDMSAKEGI

GRM5

226

P41594
GMHSKGTQTAKEEME

NEK9

941

Q8TD19
KAAVVTGMELKDMSS

ATP12A

676

P54707
MKDVRTGSHEDRMDS

EDEM3

446

Q9BZQ6
RDGAVKAMEEMNGKD

SYNCRIP

381

O60506
MMELREAFAKVDTDG

LCP1

11

P13796
ASREKGFAMEKDMKN

LCN6

41

P62502
EAREKMMAAKRADGA

SLC7A5P2

21

Q9GIP4
MEDLMSSKDDVGKSV

MYH9

1506

P35579
MERGKMAEAESLETA

EXOC6B

1

Q9Y2D4
AMLAMDTDETSKKIA

LAMA5

2616

O15230
SEMEKGGREDMDISK

NASP

176

P49321
SFGNMMSKEKREAVS

PANK2

471

Q9BZ23
ESMREHVVAASKAMK

EIF3C

731

Q99613
EGTDMKDMRLEAEAV

GSKIP

26

Q9P0R6
REMIEESANKFGMKD

CDC45

341

O75419
AMEKSGKMDVAEALE

FHAD1

1226

B1AJZ9
VKQEMEEKGSSMTDG

IFT57

356

Q9NWB7
RMFGKQVAKLESDMD

CFAP70

531

Q5T0N1
SIKSRASDVFEMMKD

GUCY2F

586

P51841
AMEKGLASLKSEMRE

LAMC2

1041

Q13753
DNKDMDMKTIFRAVG

ENPP7

356

Q6UWV6
ERDATQAGKMMDATG

ICA1L

96

Q8NDH6
KTKMGERQRAGEMTE

SEC14L2

321

O76054
KTKMGERQRAGEMTD

SEC14L3

321

Q9UDX4
KTKMGEQQSAREMTE

SEC14L4

321

Q9UDX3
TAMDMVNKSEDKDVG

KCTD3

571

Q9Y597
MSDRKAVIKNADMSE

DYNLL2

1

Q96FJ2
SMGKFEEVVKSARHM

HMGCLL1

191

Q8TB92
DMAEAHKEAMSRKLG

PSMD9

111

O00233
LKMLDMSFKDAERGD

SYNE2

1381

Q8WXH0
EARTFVKSMEDKGMT

ITIH3

346

Q06033
KEESEQMGKTSRKDM

SETX

621

Q7Z333
DSKTMKAMVEFREHT

MYCBP2

4331

O75592
ETEKEMATMKEEFGR

MYH6

846

P13533
RAKLTSDAEKESVMM

SRBD1

506

Q8N5C6
KESARSIADGAMMEA

TESC

151

Q96BS2
MDSLAAEIEGTMRKE

TRAK1

371

Q9UPV9
EEKSGMEGRKKMFES

TNNI2

166

P48788
ARASVVKDMMLGKDD

TRIM67

671

Q6ZTA4
MDDKSMAGLEDSKAN

ZFHX4

1281

Q86UP3
ADRLTETMEDGKTMD

POLR3C

126

Q9BUI4
KGNMKINETREDMDA

RNF19A

681

Q9NV58
IKKLEDFMSTMDANG

SPTBN2

1211

O15020
MMGQEKAKDELSAQA

SPTBN2

1611

O15020
GDDMKKKVRMNEDGS

RP1L1

306

Q8IWN7
VSHKAMVDMSEKGTE

SERPINA11

356

Q86U17
AQSTMSMRKKEESEA

TNS4

131

Q8IZW8
RDLSAKETKMLMAAG

PVALB

76

P20472
DSEGRMTMAFKDLKL

KCNJ16

226

Q9NPI9
RKAMRDSDSGLEKMA

MLF1

141

P58340
EDDDGGIMMRSKETS

SLC9A1

756

P19634
SDEVKRAMNKSFMES

SUGT1

321

Q9Y2Z0
SAQSEAEKERIMGKM

SNRNP200

336

O75643
GETRKMAEMKTEDGK

VPS26A

21

O75436
SREKSKATEVMADMF

TSPYL6

26

Q8N831
KATEVMADMFDGRLE

TSPYL6

31

Q8N831
ARAVISLMEMGFDEK

UBAC1

291

Q9BSL1
SDAMVMDEKVKRSFV

TMIGD3

71

P0DMS9
MKVFTKMCDIGDASR

TUT7

1151

Q5VYS8
ADKKLSEFDVEMSMR

THOP1

101

P52888
MVRCMKDDSKGKSEE

TNNC1

81

P63316
TDKVTETVMNGGMKE

PPP6R3

786

Q5H9R7
GDHDDSAMKTLRSKM

POTEH

121

Q6S545
SEKMSMEDENFRKRK

ZC3H14

281

Q6PJT7
VSMLETFGSKDDDKM

SLC16A10

96

Q8TF71