Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainARM-type_fold

SMG1 SAAL1 GBF1 DOCK11 MROH5 TRRAP ASPM UTP20 HEATR5B TNPO2 UBR4 VEPH1 SCYL3 ARFGEF1 APOB PPP4R4 PRKDC

7.26e-0833919017IPR016024
DomainARM-like

SMG1 SAAL1 SETX MROH5 TRRAP ASPM UTP20 HEATR5B TNPO2 SCYL3 ARFGEF1 PPP4R4 PRKDC

4.12e-0627019013IPR011989
DomainHEAT_REPEAT

SMG1 UTP20 HEATR5B TNPO2 SCYL3 PPP4R4 PRKDC

7.04e-06701907PS50077
Domain-

SAAL1 MROH5 TRRAP ASPM UTP20 HEATR5B TNPO2 SCYL3 ARFGEF1 PPP4R4 PRKDC

1.77e-05222190111.25.10.10
DomainFAT

SMG1 TRRAP PRKDC

2.03e-0561903PS51189
DomainFATC

SMG1 TRRAP PRKDC

2.03e-0561903PS51190
DomainFATC_dom

SMG1 TRRAP PRKDC

2.03e-0561903IPR003152
DomainPIK_FAT

SMG1 TRRAP PRKDC

2.03e-0561903IPR014009
DomainFATC

SMG1 TRRAP PRKDC

2.03e-0561903SM01343
DomainFzo_mitofusin

MFN2 MFN1

1.03e-0421902PF04799
DomainMitofusin_fam

MFN2 MFN1

1.03e-0421902IPR027094
DomainFzo/mitofusin_HR2

MFN2 MFN1

1.03e-0421902IPR006884
DomainRB_A

RB1 RBL2

3.07e-0431902IPR002720
DomainDUF3452

RB1 RBL2

3.07e-0431902PF11934
DomainRB_B

RB1 RBL2

3.07e-0431902IPR002719
DomainRB_C

RB1 RBL2

3.07e-0431902IPR015030
DomainRB_fam

RB1 RBL2

3.07e-0431902IPR028309
DomainRB_N

RB1 RBL2

3.07e-0431902IPR024599
DomainRB_A

RB1 RBL2

3.07e-0431902PF01858
DomainRB_B

RB1 RBL2

3.07e-0431902PF01857
DomainDUF3452

RB1 RBL2

3.07e-0431902SM01367
DomainRb_C

RB1 RBL2

3.07e-0431902SM01369
DomainRB_A

RB1 RBL2

3.07e-0431902SM01368
DomainP-loop_NTPase

SETX ATAD5 ZGRF1 RAB8B MCM6 SRCAP RAB8A ABCG4 ASPM MFN2 KIF14 DLG4 DYNC2H1 RNF213 DDX55 MFN1 ORC5 PSTK MYO1F CARD11

4.17e-0484819020IPR027417
DomainPOU

POU3F1 POU3F2 POU5F1

5.26e-04161903SM00352
DomainPOU_dom

POU3F1 POU3F2 POU5F1

5.26e-04161903IPR000327
Domain-

SMG1 TRRAP PRKDC

5.26e-041619031.10.1070.11
DomainPou

POU3F1 POU3F2 POU5F1

5.26e-04161903PF00157
DomainPOU_1

POU3F1 POU3F2 POU5F1

5.26e-04161903PS00035
DomainPI3Kc

SMG1 TRRAP PRKDC

5.26e-04161903SM00146
DomainPOU_2

POU3F1 POU3F2 POU5F1

5.26e-04161903PS00465
DomainPOU_3

POU3F1 POU3F2 POU5F1

5.26e-04161903PS51179
DomainSHR-BD

VPS13D VPS13B

6.09e-0441902IPR009543
DomainTF_POU_3

POU3F1 POU3F2

6.09e-0441902IPR016362
DomainMatrilin_ccoil

MATN2 MATN3

6.09e-0441902SM01279
Domain-

MATN2 MATN3

6.09e-04419021.20.5.30
DomainMatrilin_ccoil

MATN2 MATN3

6.09e-0441902PF10393
DomainSec7_N

GBF1 ARFGEF1

6.09e-0441902IPR032691
DomainVPS13_C

VPS13D VPS13B

6.09e-0441902PF16909
DomainSec7_N

GBF1 ARFGEF1

6.09e-0441902PF12783
DomainMatrilin_coiled-coil_trimer

MATN2 MATN3

6.09e-0441902IPR019466
DomainVPS13_C

VPS13D VPS13B

6.09e-0441902IPR031645
DomainSHR-BD

VPS13D VPS13B

6.09e-0441902PF06650
Domain-

SETX ATAD5 ZGRF1 RAB8B MCM6 SRCAP RAB8A ABCG4 MFN2 DLG4 DYNC2H1 RNF213 DDX55 MFN1 ORC5 PSTK MYO1F CARD11

6.27e-04746190183.40.50.300
DomainPOU

POU3F1 POU3F2 POU5F1

6.34e-04171903IPR013847
DomainPI3_PI4_kinase

SMG1 TRRAP PRKDC

7.56e-04181903PF00454
DomainPI3_4_KINASE_1

SMG1 TRRAP PRKDC

7.56e-04181903PS00915
DomainPI3_4_KINASE_2

SMG1 TRRAP PRKDC

7.56e-04181903PS00916
DomainPI3/4_kinase_cat_dom

SMG1 TRRAP PRKDC

7.56e-04181903IPR000403
DomainPI3_4_KINASE_3

SMG1 TRRAP PRKDC

7.56e-04181903PS50290
DomainFATC

SMG1 PRKDC

1.01e-0351902PF02260
Domainfn3

PTPRG MID1 COL12A1 DSCAM IGSF9B EPHA10 EPHA5

1.37e-031621907PF00041
DomainHEAT

UTP20 TNPO2 SCYL3 PRKDC

1.42e-03481904PF02985
DomainSURP

U2SURP SUGP2

1.50e-0361902PS50128
DomainSurp

U2SURP SUGP2

1.50e-0361902PF01805
DomainSWAP

U2SURP SUGP2

1.50e-0361902SM00648
DomainFAT

TRRAP PRKDC

1.50e-0361902PF02259
DomainPIK-rel_kinase_FAT

TRRAP PRKDC

1.50e-0361902IPR003151
DomainSurp

U2SURP SUGP2

1.50e-0361902IPR000061
DomainEphrin_rec_like

ELAPOR1 EPHA10 EPHA5

2.02e-03251903SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

ELAPOR1 EPHA10 EPHA5

2.02e-03251903IPR011641
DomainRho_GTPase_activation_prot

BCR ARHGAP21 OPHN1 FAM13A PLXNC1

2.05e-03881905IPR008936
DomainCarn_acyl_trans

CPT2 CROT

2.09e-0371902IPR000542
DomainCarn_acyltransf

CPT2 CROT

2.09e-0371902PF00755
DomainACYLTRANSF_C_1

CPT2 CROT

2.09e-0371902PS00439
DomainACYLTRANSF_C_2

CPT2 CROT

2.09e-0371902PS00440
DomainZnf_GRF

ZGRF1 NEIL3

2.09e-0371902IPR010666
Domainzf-GRF

ZGRF1 NEIL3

2.09e-0371902PF06839
DomainVWA

MATN2 MATN3 COL12A1 ITGA10

2.52e-03561904PF00092
Domain-

POU3F1 POU3F2 POU5F1

2.53e-032719031.10.260.40
DomainChorein_N

VPS13D VPS13B

2.77e-0381902PF12624
DomainVPS13_N

VPS13D VPS13B

2.77e-0381902IPR026854
DomainHEAT

UTP20 TNPO2 SCYL3 PRKDC

2.87e-03581904IPR000357
DomainFN3

PTPRG MID1 COL12A1 DSCAM IGSF9B EPHA10 EPHA5

2.90e-031851907SM00060
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

SETX GBF1 HK2 MCM6 FOXA2 TRRAP LIN9 UTP20 LRRC41 COPA RB1 RBL2 UBR4 FRMPD1 CPOX ORC5 FOXD3 SUGP2 TLE4 CTBP2

9.06e-088571952025609649
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

GBF1 HK2 SRP14 MCM6 NOL10 HMGCL PGAM1 CKB KIF14 UTP20 DLST TDRD6 MAP4K4 FLII COPA DYNC2H1 U2SURP UBR4 LRRC40 APOB CPOX DDX55 POLR3A CTBP2 PRKDC USP39

1.30e-0714251952630948266
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CYLD GRIPAP1 SETX TASOR2 ARHGAP21 IGSF3 DSCAM CCDC146 SCYL3 ARFGEF1 ZC3HC1 RNF213 APOB KBTBD2 LIG1 SUGP2 UNC5C PRKDC

4.58e-077771951835844135
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CYLD ANO9 SAAL1 SETX SRCAP MED24 AREL1 KCNH1 ARHGAP21 PML AKAP6 FRMPD1 OAS1 APOB CPT2 SLC44A1 CSNK1G3 TLE4 UNC5C PAN3 VPS13B

8.98e-0710841952111544199
Pubmed

Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1.

RAB8A UCP1 DRD2 COL12A1

1.65e-061619548649810
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETX HK2 SRP14 MCM6 NOL10 SRCAP LARP4 TRRAP ASPM MLH1 UTP20 DLST PRR14L FLII COPA RB1 U2SURP UBR4 LRRC40 POLR3A SUGP2 CTBP2 PRKDC

2.42e-0613531952329467282
Pubmed

Defining the membrane proteome of NK cells.

GBF1 HK2 PDGFRA TMEM237 LARP4 BCR PGAM1 MLH1 KIF14 DLST HEATR5B LRRC41 COPA UBR4 RNF213 LRRC40 DDX55 POLR3A SLC44A1 PLXNC1 PRKDC

2.90e-0611681952119946888
Pubmed

The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates.

POU3F1 POU3F2 POU5F1

3.43e-066195321185279
Pubmed

PDGF signalling controls age-dependent proliferation in pancreatic β-cells.

PDGFRA RB1 RBL2

3.43e-066195321993628
Pubmed

Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer.

RB1 RBL2 PRKDC

3.43e-066195327373157
Pubmed

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.

RB1 RBL2 PRKDC

3.43e-066195321875955
Pubmed

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.

LIN9 RB1 RBL2

3.43e-066195315479636
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

GRIPAP1 FRS3 MCM6 TASOR2 MLH1 DLG4 PML SCYL3 SPTBN4 FAM13A DACH2 CTBP2 MAPKBP1 GPSM1

3.83e-065601951421653829
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SETX DOCK11 FBXL7 UTP20 CCDC170 CFAP47 RB1 TNPO2 UBR4 RNF213 LRRC40 GRIN1 ZBTB44 IGSF9B PRKDC USP39

4.58e-067361951629676528
Pubmed

Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer.

RB1 RBL2 PRKDC

5.98e-067195338788720
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 RAB8B CCNO SRP14 HMGCL SRCAP PGAM1 TASOR2 RAB8A ASPM DLST ARHGAP21 COPA U2SURP UBR4 APOB CPOX ZFC3H1 DDX55 PPP4R4 SPTBN4 UNC5C PRKDC

6.89e-0614421952335575683
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SMG1 DOCK11 SRP14 MCM6 SRCAP LARP4 TRRAP MIOS PML ZFC3H1 DDX55 THAP12

8.06e-064401951234244565
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

CYLD GRIPAP1 GBF1 BCR KIF14 MAP4K4 FLII POLR3A ALG13

1.34e-05251195929778605
Pubmed

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.

SETX RAB8B RB1CC1 RAB8A UBR4

1.59e-0556195527103069
Pubmed

Tel2 regulates the stability of PI3K-related protein kinases.

SMG1 TRRAP PRKDC

2.02e-0510195318160036
Pubmed

Real-time resolution of point mutations that cause phenovariance in mice.

MAP4K4 KBTBD2 PRKDC

2.02e-0510195325605905
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MCM6 NOL10 LARP4 PGAM1 TRRAP TASOR2 CKB KIF14 UTP20 COPA U2SURP UBR4 SUGP2 PRKDC

2.14e-056531951422586326
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

CTTNBP2 PGAM1 CKB PRR14L TAF4B HEATR5B FLII UBR4 MINPP1 INTS8 POLR3A FOXD3 PRKDC

2.37e-055731951328330616
Pubmed

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.

CISH KIF14 IL17RA CPT2 LIG1

2.43e-0561195527694478
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

TTC39B TREX1 CTTNBP2 GBF1 MATN3 TRRAP CISH FBXL7 ASPM DLG4 SMYD3 ASTE1 ZC3HC1 OAS1 GRIN1 CPT2 DDX55 CSNK1G3 WFIKKN2 ALG13

2.49e-0512421952030973865
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

SMG1 TRRAP PRKDC

2.77e-0511195320427287
Pubmed

Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.

DLG4 GRIN1 EPHA5

2.77e-0511195320824214
Pubmed

Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells.

MFN2 MFN1

3.13e-052195231431479
Pubmed

Silencing of RB1 and RB2/P130 during adipogenesis of bone marrow stromal cells results in dysregulated differentiation.

RB1 RBL2

3.13e-052195224281253
Pubmed

A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space.

MFN2 MFN1

3.13e-052195229212658
Pubmed

Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML.

PML RB1

3.13e-05219529671498
Pubmed

Structural basis for RNA polymerase III transcription repression by Maf1.

MAF1 POLR3A

3.13e-052195232066962
Pubmed

Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors.

DLG4 GRIN1

3.13e-05219529502803
Pubmed

Hijacking components of the cellular secretory pathway for replication of poliovirus RNA.

GBF1 ARFGEF1

3.13e-052195217079330
Pubmed

Loss of mitofusin 2 promotes endoplasmic reticulum stress.

MFN2 MFN1

3.13e-052195222511781
Pubmed

The retinoblastoma-related gene, RB2, maps to human chromosome 16q12 and rat chromosome 19.

RB1 RBL2

3.13e-05219528247552
Pubmed

Mitofusin 2 tethers endoplasmic reticulum to mitochondria.

MFN2 MFN1

3.13e-052195219052620
Pubmed

The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein.

PML RB1

3.13e-05219529448006
Pubmed

Overlapping roles of pocket proteins in the myocardium are unmasked by germ line deletion of p130 plus heart-specific deletion of Rb.

RB1 RBL2

3.13e-052195215743840
Pubmed

Adult skeletal muscle deletion of Mitofusin 1 and 2 impedes exercise performance and training capacity.

MFN2 MFN1

3.13e-052195230260752
Pubmed

p600, a unique protein required for membrane morphogenesis and cell survival.

RB1 UBR4

3.13e-052195216214886
Pubmed

Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells.

MFN2 MFN1

3.13e-052195221839087
Pubmed

Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells.

DLG4 GRIN1

3.13e-052195220577261
Pubmed

Structural basis of mitochondrial tethering by mitofusin complexes.

MFN2 MFN1

3.13e-052195215297672
Pubmed

Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group.

TLX1 TLX3

3.13e-052195218368072
Pubmed

Mitochondrial toxic effects of Aβ through mitofusins in the early pathogenesis of Alzheimer's disease.

MFN2 MFN1

3.13e-052195224710686
Pubmed

CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling.

CYLD CARD11

3.13e-052195220233721
Pubmed

Mitofusin1 in oocyte is essential for female fertility.

MFN2 MFN1

3.13e-052195230690319
Pubmed

The effect of gestational diabetes on the expression of mitochondrial fusion proteins in placental tissue.

MFN2 MFN1

3.13e-052195234600274
Pubmed

Isolation, characterization and mapping of the mouse and human RB1CC1 genes.

RB1CC1 RB1

3.13e-052195212095676
Pubmed

The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins.

FRMPD1 GPSM1

3.13e-052195218566450
Pubmed

Mitochondrial Dynamics in Tachycardiomyopathy.

MFN2 MFN1

3.13e-052195230873819
Pubmed

MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.

MFN2 MFN1

3.13e-052195233674260
Pubmed

Expression of integrin alpha 10 is transcriptionally activated by pRb in mouse osteoblasts and is downregulated in multiple solid tumors.

RB1 ITGA10

3.13e-052195224287699
Pubmed

Gene profiling approaches help to define the specific functions of retinoblastoma family in epidermis.

RB1 RBL2

3.13e-052195217932948
Pubmed

Endoplasmic reticulum-mitochondrial interaction mediated by mitofusin-1 or mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation.

MFN2 MFN1

3.13e-052195227404125
Pubmed

Mitofusin 1 overexpression rescues the abnormal mitochondrial dynamics caused by the Mitofusin 2 K357T mutation in vitro.

MFN2 MFN1

3.13e-052195237220142
Pubmed

A catalytic domain variant of mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion.

MFN2 MFN1

3.13e-052195230936207
Pubmed

Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells.

RB1 RBL2

3.13e-052195223370776
Pubmed

Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells.

RB1 POU3F2

3.13e-052195217163992
Pubmed

RB family tumor suppressor activity may not relate to active silencing of E2F target genes.

RB1 RBL2

3.13e-052195225056122
Pubmed

Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk.

MFN2 MFN1

3.13e-052195222777004
Pubmed

Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein.

LIN9 RB1

3.13e-052195215538385
Pubmed

Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.

MFN2 MFN1

3.13e-052195224074867
Pubmed

Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations.

MFN2 MFN1

3.13e-052195217296794
Pubmed

Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells.

MFN2 MFN1

3.13e-052195232281181
Pubmed

Arsenite inhibits the function of CD133+ CD13+ liver cancer stem cells by reducing PML and Oct4 protein expression.

PML POU5F1

3.13e-052195227517564
Pubmed

The retinoblastoma protein and PML collaborate to organize heterochromatin and silence E2F-responsive genes during senescence.

PML RB1

3.13e-052195224351540
Pubmed

Simultaneous visualization of Q-bands and FISH signals using a novel fluorochrome.

FOXA2 RB1

3.13e-05219527606937
Pubmed

MFN2 Plays a Distinct Role from MFN1 in Regulating Spermatogonial Differentiation.

MFN2 MFN1

3.13e-052195232330448
Pubmed

Changes in cortical N-methyl-D-aspartate receptors and post-synaptic density protein 95 in schizophrenia, mood disorders and suicide.

DLG4 GRIN1

3.13e-052195226013316
Pubmed

Dynamic assembly of ribbon synapses and circuit maintenance in a vertebrate sensory system.

DLG4 CTBP2

3.13e-052195231092821
Pubmed

RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells.

RB1CC1 RB1

3.13e-052195214533007
Pubmed

Mfn2 is critical for brown adipose tissue thermogenic function.

MFN2 MFN1

3.13e-052195228348166
Pubmed

Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.

MFN2 MFN1

3.13e-052195230882371
Pubmed

Recent ultra-rare inherited variants implicate new autism candidate risk genes.

KCNH1 DSCAM

3.13e-052195234312540
Pubmed

MFN1 and MFN2 Are Dispensable for Sperm Development and Functions in Mice.

MFN2 MFN1

3.13e-052195234948301
Pubmed

The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression.

POU5F1 FOXD3

3.13e-052195211891324
Pubmed

The heptad repeat domain 1 of Mitofusin has membrane destabilization function in mitochondrial fusion.

MFN2 MFN1

3.13e-052195229661855
Pubmed

Expression and regulation of RB1CC1 in developing murine and human tissues.

RB1CC1 RB1

3.13e-052195215375585
Pubmed

Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells.

MFN2 MFN1

3.13e-052195212759376
Pubmed

Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo.

MFN2 MFN1

3.13e-052195211950885
Pubmed

Control of mitochondrial morphology by a human mitofusin.

MFN2 MFN1

3.13e-052195211181170
Pubmed

Evaluation of the role of mitofusin-1 and mitofusin-2 in periodontal disease.

MFN2 MFN1

3.13e-052195237436713
Pubmed

Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion.

MFN2 MFN1

3.13e-052195224813948
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CYLD CTTNBP2 DOCK11 BCR MIOS MFN2 DLG4 MAP4K4 ARHGAP21 FLII DSCAM UBR4 TPPP GRIN1 SPTBN4 CCDC88C CTBP2

3.36e-059631951728671696
Pubmed

Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.

MFN2 CPT2 MFN1 OPHN1

3.45e-0533195422904094
Pubmed

Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast.

FOXA2 POU3F1 POU5F1

3.68e-0512195327292645
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

HK2 NOL10 LARP4 RAB8A FBXL4 CKB MFN2 DLST FLII COPA UBR4 RNF213 LRRC40 CPOX CPT2 DDX55 MFN1 POLR3A GEMIN7 VPS13D VPS13B ALG13

3.79e-0514961952232877691
Pubmed

Mitochondrial function and intracellular distribution is severely affected in in vitro cultured mouse embryos.

MFN2 POU5F1 MFN1

4.76e-0513195336167966
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CYLD CTTNBP2 GBF1 DOCK11 RAB8A KIF14 MAP4K4 CCDC88C PRKDC THAP12 ALG13

4.82e-054461951124255178
Pubmed

Human transcription factor protein interaction networks.

CYLD SMG1 ATAD5 SRCAP LARP4 TRRAP LIN9 RAB8A TLX1 CKB MED24 PML COPA RB1 TNPO2 UBR4 TLX3 SUGP2 TLE4 CTBP2 PAN3

5.80e-0514291952135140242
Pubmed

Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.

POU3F1 POU3F2 TLE4

6.04e-0514195315273690
Pubmed

Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.

RB1CC1 SRCAP TRRAP

6.04e-0514195328263302
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CYLD ATAD5 SRP14 SRCAP BCR TRRAP MLKL ASPM MLH1 DLG4 TAF4B LRRC41 PML WDR72 RB1 RNF213 SUGP2 ALG13

6.30e-0511161951831753913
Pubmed

A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.

HK2 PGAM1 UCP1 POU5F1

6.76e-0539195433059001
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

MCM6 LARP4 COPA RBL2 U2SURP LAMP2 PRKDC

7.20e-05179195736261009
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

IRF6 FLII RB1 DYNC2H1 RBL2 TNPO2 LRRC40 GEMIN7 CTBP2 PRKDC

9.15e-053981951035016035
Pubmed

Cytoplasmic and nuclear interaction between Rb family proteins and PAI-2: a physiological crosstalk in human corneal and conjunctival epithelial cells.

RB1 RBL2

9.35e-053195216397580
Pubmed

Retinoblastoma family proteins have distinct functions in pulmonary epithelial cells in vivo critical for suppressing cell growth and tumorigenesis.

RB1 RBL2

9.35e-053195219887614
InteractionGYPA interactions

SMG1 SAAL1 SETX GBF1 NEK6 TMEM237 MFN2 KIF14 UTP20 RB1 DYNC2H1 TNPO2 ORC5

1.11e-0817419013int:GYPA
InteractionC3orf18 interactions

SMG1 SAAL1 MFN2 KIF14 UTP20 DYNC2H1 TNPO2 ORC5 PRKDC

1.45e-061151909int:C3orf18
InteractionC19orf38 interactions

SAAL1 SETX KIF14 DYNC2H1 TNPO2 RNF213 ORC5 PRKDC

1.53e-06861908int:C19orf38
InteractionHERC4 interactions

CYLD DOCK11 FDXACB1 WDR72 FLII RB1 UBR4

1.14e-05811907int:HERC4
InteractionNPTN interactions

SMG1 SETX GBF1 KIF14 UTP20 HEATR5B DYNC2H1 TNPO2 ARFGEF1 RNF213 INTS8 MFN1

1.38e-0527819012int:NPTN
InteractionAKAP1 interactions

HK2 RAB8B LARP4 TRRAP RAB8A FBXL4 CKB MFN2 UTP20 LRRC41 FLII UBR4 MFN1 VPS13D KBTBD4 ALG13

2.39e-0550319016int:AKAP1
Cytoband2p24-p23

MATN3 APOB

1.79e-05219522p24-p23
Cytoband1q44

OR2G6 OR2M5 OR2M3 SMYD3 LYPD8

1.12e-0411019551q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2G6 OR2M5 OR2M3 SMYD3 LYPD8

2.28e-041281955chr1q44
Cytoband8q11

RB1CC1 PRKDC

2.66e-04619528q11
Cytoband1p36.22

MFN2 CENPS VPS13D

5.27e-043719531p36.22
GeneFamilyFibronectin type III domain containing

PTPRG MID1 COL12A1 DSCAM IGSF9B EPHA10 EPHA5

1.74e-041601327555
GeneFamilyPOU class homeoboxes and pseudogenes

POU3F1 POU3F2 POU5F1

6.05e-04231323523
GeneFamilyZinc fingers GRF-type|Topoisomerases

ZGRF1 NEIL3

1.08e-0371322135
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PDGFRA PXDNL DSCAM WFIKKN2 UNC5C IGSF9B

1.18e-031611326593
CoexpressionGAUTAM_EYE_CORNEA_CYTOTOXIC_T_CELLS

MATN2 FBXL4 MLKL ASPM SMYD3 FDXACB1 PHOSPHO2 PSTK FAM13A MAPKBP1

1.73e-0714819510M43625
CoexpressionLASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN

GBF1 HMGCL PGAM1 ABCG4 MLH1 MFN2 FDXACB1 LRRC41 DYNC2H1 UBR4 LRRC40 CENPS MINPP1 POLR3A ZBTB44 PSTK VPS13D CTBP2 THAP12 EPHA10

2.79e-0680719520M14594
CoexpressionDING_LUNG_CANCER_BY_MUTATION_RATE

SMG1 PDGFRA PTPRG PRKDC

1.31e-05201954M1189
CoexpressionULE_SPLICING_VIA_NOVA2

MAP4K4 ARHGAP21 CACNA1B GRIN1 EPHA5

1.66e-05431955M1551
CoexpressionULE_SPLICING_VIA_NOVA2

MAP4K4 ARHGAP21 CACNA1B GRIN1 EPHA5

1.66e-05431955MM666
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPROGBP

HK2 ZGRF1 MCM6 FOXA2 MID1 ASPM KIF14 VEPH1 POU3F1 POU3F2 CROT

1.66e-0530019511M39059
CoexpressionGSE4811_CLASSSICALY_ACTIVATED_VS_TYPE_2_ACTIVATED_MACROPHAGE_DN

MATN2 DLG4 TNPO2 VEPH1 CASR POU3F2 GRIN1 FOXD3 TAS1R2

2.01e-052001959M6548
CoexpressionBENPORATH_ES_WITH_H3K27ME3

PDGFRA FOXA2 TLX1 ABCG4 KCNH1 UCP1 ELAPOR1 CACNA1B COL12A1 TLX3 FRMPD1 POU3F1 POU3F2 GRIN1 TRIM7 SPTBN4 FOXD3 DACH2 PLXNC1 UNC5C EPHA10 EPHA5

3.15e-05111519522M10371
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPROGFPL

TSPAN18 HK2 ATAD5 MCM6 FOXA2 FBXL7 MID1 ASPM KIF14 VEPH1 POU3F1

3.19e-0532219511M39060
CoexpressionGSE14415_INDUCED_VS_NATURAL_TREG_DN

HK2 ATAD5 GPR55 ASPM KIF14 TDRD6 CENPS NEIL3

6.63e-051811958M2969
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP

ATAD5 MCM6 ASPM KIF14 RNF213 CENPS LIG1 NEIL3

7.16e-051831958M2993
CoexpressionRIEGE_DELTANP63_DIRECT_TARGETS_UP

TMEM237 IRF6 KIF14 PPP4R4 TRIM7 LIG1 MAPKBP1

8.07e-051381957M41739
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_200

LYPD6 PDGFRA MATN2 COL12A1 RNF213 TEX15 PPP4R4 PLXNC1

4.34e-051431898gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_200
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

CYLD TTC39B ZGRF1 TASOR2 KIF14 TAF4B RB1 CENPS POU5F1 TEX15 PDE5A PRKDC ALG13

4.37e-0538518913gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

TTC39B SETX ZGRF1 LARP4 TASOR2 CKB KIF14 UTP20 TAF4B CCDC170 RB1 RNF213 LRRC40 CENPS POU5F1 TEX15 LIG1 PDE5A PRKDC ALG13

4.70e-0582218920gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_100

LYPD6 PDGFRA MATN2 COL12A1 RNF213 PLXNC1

5.56e-05751896gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_100
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TTC39B TSPAN18 HK2 CCNO FBXL7 TAF4B TLE4 CARD11 CTBP2

1.46e-0718719597e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 MATN2 RB1CC1 LARP4 KCNH1 MAP4K4 COPA LAMP2 PAN3

2.48e-0719919598d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellLymphoid-Lymphoid-T_cells_(Cd8+_T_cell)|Lymphoid / shred on cell class and cell subclass (v4)

RAB8B MATN2 MCM6 NOL10 CKB FLII MYO1F CTBP2

8.67e-07170195820fd1a312c81c1bf3c5d2d6caf9b578e6b7a4171
ToppCelldroplet-Marrow-BM-30m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 MCM6 ABCG4 ST3GAL6 SLC43A3 MINPP1 CPOX LIG1

1.84e-061881958f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

ATAD5 MCM6 ASPM UTP20 IGSF3 WDR72 LIG1 PRKDC

1.92e-061891958946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellsevere_COVID-19-T/NK_proliferative|severe_COVID-19 / disease group, cell group and cell class (v2)

TMEM237 ATAD5 ZGRF1 MCM6 ASPM KIF14 CENPS LIG1

2.71e-061981958ed86b0247006befe55400c287d334d2202b470bd
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 PTPRG TDRD6 CACNA1B COL12A1 UNC5C EPHA5

6.87e-061601957c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 PTPRG TDRD6 CACNA1B COL12A1 UNC5C EPHA5

6.87e-06160195725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 CCNO MCM6 ELAPOR1 WDR72 CENPS LIG1

8.08e-0616419576ea188e17895961cd112152fb111d08641cc5e45
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 ASPM KIF14 TEX15 LIG1 NEIL3

9.83e-0616919570bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNO ELAPOR1 CFAP47 DRD2 CCDC146 CFAP52 FAM13A

1.06e-0517119574f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ATAD5 MCM6 TASOR2 DYNC2H1 ITGA10 CENPS LIG1

1.10e-0517219577c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ATAD5 ZGRF1 ASPM LRRC40 LIG1 NEIL3 RNF207

1.14e-05173195720889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ATAD5 ZGRF1 ASPM LRRC40 LIG1 NEIL3 RNF207

1.14e-05173195746e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATAD5 LIN9 ASPM KIF14 CENPS LIG1 LIPI

1.43e-051791957ac987c9425a1b4106d1b8779a2c5461383eae2ae
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA ATAD5 MCM6 CKB CENPS LIG1 PDE5A

1.43e-051791957ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 MID1 POU3F1 PPP4R4 FOXD3 IGSF9B EPHA5

1.59e-051821957c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATAD5 MCM6 KIF14 SMYD3 LIG1 NEIL3 ALG13

1.65e-0518319576c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

GBF1 MATN2 GPR55 MIOS RNF213 INTS8 ORC5

1.89e-051871957689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 LIN9 FBXL7 ASPM KIF14 NEIL3

1.89e-051871957e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GBF1 MATN2 GPR55 MIOS RNF213 INTS8 ORC5

1.89e-0518719574527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 LIN9 FBXL7 ASPM KIF14 NEIL3

1.89e-051871957cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 ELAPOR1 ASPM KIF14 LIG1 NEIL3

1.89e-0518719579351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 RB1CC1 TASOR2 ARFGEF1 RNF213 FAM13A GPCPD1

1.96e-051881957ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA ASPM KIF14 POU3F1 CENPS PDE5A NEIL3

1.96e-05188195795d0a796d62ce6d121e2028c378faffc14b35275
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 MCM6 ABCG4 ST3GAL6 SLC43A3 CPOX LIG1

2.03e-05189195716dfc37d8d390ed7f927bc844c47c9c5a89a0928
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 MCM6 ABCG4 ST3GAL6 SLC43A3 CPOX LIG1

2.03e-0518919573ade3fa9369e85304b20d7233b581f18ad5ecc89
ToppCelldroplet-Marrow-nan-24m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM6 ABCG4 ST3GAL6 SLC43A3 MINPP1 CPOX LIG1

2.03e-05189195798ace332c3c046694c6ade47de8c8bf57ec51271
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TSPAN18 CKB PXDNL COL12A1 ITGA10 CCDC88C DACH2

2.10e-051901957938d1f66094b1c94606e0d40213a39e5112f3322
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATAD5 MCM6 LIN9 ASPM KIF14 LIG1 NEIL3

2.17e-05191195715dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD6 IRF6 CISH IGSF3 FRMPD1 TPPP PLXNC1

2.17e-0519119574bfdf44d4402a42530d30c89d94946acdda4321b
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATAD5 MCM6 LIN9 ASPM KIF14 LIG1 NEIL3

2.17e-05191195745c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM6 ABCG4 ST3GAL6 SLC43A3 MINPP1 CPOX LIG1

2.17e-05191195724ebc8d4a9fc3782510162e04fe586f7cb371eed
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 MCM6 ASPM KIF14 LRRC40 LIG1 NEIL3

2.24e-051921957e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCellNS-critical-d_0-4-Epithelial-Basal|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATAD5 FBXL7 DLG4 TRIM7 ORC5 SUGP2 RNF207

2.32e-0519319571affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM237 ATAD5 LIN9 ASPM KIF14 CENPS LIG1

2.32e-051931957cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-22|World / Primary Cells by Cluster

CTTNBP2 SRP14 ELAPOR1 ARHGAP21 POU3F2 CCDC88C FAM13A

2.32e-0519319573b927d4b8ecb21a408424ef91a23746c21741f49
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA ZGRF1 MCM6 CENPS GRIN1 LIG1 PDE5A

2.40e-051941957af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 GBF1 MATN2 CKB GRIN1 PDE5A GPSM1

2.48e-051951957bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

ATAD5 ZGRF1 ASPM KIF14 LIG1 NEIL3 CARD11

2.48e-051951957764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellsevere_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

TMEM237 ATAD5 MCM6 ASPM KIF14 CENPS LIG1

2.64e-051971957189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC39B HK2 CKB VEPH1 FAM13A UNC5C LYPD8

2.73e-051981957efdbac7a3a02bff4ca48841772e0c136556c2b9b
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 RB1CC1 LARP4 MAP4K4 COPA LAMP2 PAN3

2.73e-0519819572f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellCOVID-19_Moderate-T/NK_proliferative|COVID-19_Moderate / disease group, cell group and cell class

ATAD5 ZGRF1 MCM6 ASPM KIF14 LIG1 NEIL3

2.73e-051981957166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCellCOVID-19_Moderate-T/NK_proliferative|World / disease group, cell group and cell class

ATAD5 ZGRF1 MCM6 ASPM KIF14 LIG1 NEIL3

2.73e-051981957bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SRP14 ST3GAL6 ELAPOR1 ARHGAP21 POU3F2 FAM13A EPHA5

2.73e-05198195732d58379a89be19b6b1a494bf033416546771c19
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 RB1CC1 LARP4 MAP4K4 COPA LAMP2 PAN3

2.73e-051981957f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATAD5 ZGRF1 MCM6 ASPM KIF14 LIG1 NEIL3

2.73e-051981957bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
ToppCell(0)_NK_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ATAD5 ZGRF1 MCM6 ASPM KIF14 LIG1 NEIL3

2.73e-0519819575ebb4965b723302152b42bfaf48bb77a57dd02c5
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATAD5 ZGRF1 ASPM KIF14 TEX15 NEIL3

2.78e-0513419564d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ATAD5 ZGRF1 MCM6 ASPM KIF14 CENPS LIG1

2.82e-05199195711c3d9fe811a4619347f47d2b0e94066e3085625
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 TTC39B ARFGEF1 RNF213 ZFC3H1 SUGP2 VPS13B

2.82e-051991957f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATAD5 ZGRF1 MCM6 ASPM KIF14 CENPS LIG1

2.82e-05199195736c80907b2ec1cbcd1b4e841e6c02a4792591d74
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ATAD5 ZGRF1 MCM6 ASPM KIF14 CENPS LIG1

2.82e-051991957bf4c31902ae8358215245a2e11b5a2fe4ca1bc8c
ToppCellCOVID-19_Mild-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Mild / Disease group, lineage and cell class

ATAD5 ZGRF1 MCM6 ASPM KIF14 CENPS LIG1

2.82e-051991957ddea0e5c1cb6a096ab8e09a8c3c37c1bff381d9c
ToppCelltumor_Lung-T/NK_cells-Undetermined|tumor_Lung / Location, Cell class and cell subclass

ATAD5 MCM6 PGAM1 ASPM KIF14 LIG1 NEIL3

2.82e-0519919572e222e2e080bc2be63d0fdf285e1790676b911ef
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATAD5 ZGRF1 MCM6 ASPM KIF14 CENPS LIG1

2.82e-0519919577beb0e07a27fea94674f24eb61c381b0de38ed3e
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

ATAD5 MCM6 TRRAP SLC43A3 CCDC88C LIG1 PAN3

2.91e-052001957691b3edf7d8449556e8bf611662eb85772959f0f
ToppCellBiopsy_IPF-Epithelial-Differentiating_Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

CCNO CKB ELAPOR1 CCDC170 CCDC146 DYNC2H1 CFAP52

2.91e-0520019578dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

ATAD5 MCM6 TRRAP SLC43A3 CCDC88C LIG1 PAN3

2.91e-05200195736a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCellSigmoid-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

SETX ATAD5 MCM6 KIF14 SLC43A3 CPT2 LIG1

2.91e-052001957372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell|GW08 / Sample Type, Dataset, Time_group, and Cell type.

ATAD5 MCM6 TRRAP SLC43A3 CCDC88C LIG1 PAN3

2.91e-0520019574e077aa7faddcebdfc54667f8b3990704441005b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

ATAD5 MCM6 TRRAP SLC43A3 CCDC88C LIG1 PAN3

2.91e-052001957d17ba4239e1fd702a3d757687110f0f2c6f91ef7
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HK2 GPR55 CCDC170 CENPS LIG1 ALG13

6.50e-0515619568349604bd801e20d33770f7d8243598c3756302b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSPAN18 UFSP2 MATN2 IRF6 APOB THAP12

6.50e-0515619567569cab30caafcb273e8ef0b73c9e1bf87076984
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA MCM6 CKB KCNG2 LIG1 PDE5A

8.01e-0516219563f264263878af630921911c2b344ac56eb1e7099
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CTTNBP2 TSPAN18 FBXL7 PXDNL DACH2 IGSF9B

8.57e-051641956e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 MCM6 LIN9 KIF14 LIG1

8.86e-05165195688681101d7cf60b99b8ace5d8c0944323b937306
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD6 LIN9 MLH1 NSUN7 IGSF9B ALG13

8.86e-0516519561703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellBronchial_Brush-Epithelial-Goblet_2|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

HK2 MATN3 UTP20 PML CARD11 GPSM1

9.16e-0516619568ac0a769be886d16642e7e6334471ebadd1a426b
ToppCellBronchial_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

HK2 MATN3 UTP20 PML CARD11 GPSM1

9.47e-051671956806d1c00c137da0c5f042adf866873eb6dd4bb27
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CYLD CISH IGSF3 VEPH1 IGSF9B RNF207

9.79e-0516819565e721268f0baa51d3f640f7f4c41db769ebef210
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

GRIPAP1 CTTNBP2 RB1CC1 ST3GAL6 PLXNC1 MYO1F

9.79e-051681956bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEK6 GPR55 CKB CCDC146 SPTBN4 PLXNC1

1.01e-04169195646f0f0de9a0894c454f93032e7a7a800f47c8276
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZGRF1 MCM6 CENPS SLC43A3 LIG1 NEIL3

1.19e-04174195666555c610251ea04f968c258e312d720c18e7cde
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRA PTPRG COL12A1 ITGA10 DACH2 PDE5A

1.22e-0417519561799a7be623dc3bf53ba580a7c47d2619969d708
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREX1 NEK6 BCR TMEM86A CARD11 LYPD8

1.26e-041761956d4075796c38b775fe721abb47426e662a0d415e3
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD5 MCM6 CENPS CCDC88C LIG1 NEIL3

1.26e-0417619569e719e6323597ecfc758c957256872cd4ae24d4d
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMG1 RAB8B SCYL3 POLR3A SUGP2 PLXNC1

1.34e-041781956c87945146b2734141f07b39d268e0d8086ee0364
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTC39B NEK6 MCM6 LIN9 SCYL3 LIG1

1.38e-0417919569dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCelldroplet-Bladder-nan-24m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 AKAP6 CCDC146 POU3F1 SLC43A3 FOXD3

1.38e-0417919563d6bb3cfe89d60f2f00aead9341f9967e5313763
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 MCM6 LIG1 NEIL3 PRKDC

1.38e-04179195688d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 MCM6 KIF14 LIG1 NEIL3

1.38e-04179195680112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 ASPM KIF14 CASR NEIL3

1.43e-041801956401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 ASPM KIF14 LIG1 NEIL3

1.43e-041801956f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEK6 LARP4 BCR LRRC41 TNPO2 ITGA10

1.47e-041811956e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 KCNH1 COL12A1 POU3F1 FOXD3 SLC44A1

1.47e-0418119560b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTTNBP2 PDGFRA COL12A1 APOB DACH2 PNPLA7

1.47e-041811956b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEK6 LARP4 BCR LRRC41 TNPO2 ITGA10

1.47e-041811956d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCellHSPCs-Erythroblasts|World / Lineage and Cell class

ABCG4 ST3GAL6 MINPP1 CPOX ORC5 LIG1

1.47e-041811956ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 HK2 DOCK11 FBXL7 UNC5C IGSF9B

1.47e-0418119565f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 HK2 DOCK11 FBXL7 UNC5C IGSF9B

1.47e-041811956c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T|Liver / Manually curated celltypes from each tissue

ATAD5 MCM6 ASPM KIF14 LIG1 NEIL3

1.52e-04182195681557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 POU3F1 POU3F2 FOXD3 SLC44A1 IGSF9B

1.52e-04182195682ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

CTTNBP2 FBXL7 ST3GAL6 DACH2 UNC5C GPSM1

1.56e-041831956fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellControl-T/NK_proliferative|Control / Disease group and Cell class

CKB ASPM KIF14 POU3F1 CENPS NEIL3

1.56e-04183195609c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA ARHGAP21 PML ZFC3H1 PDE5A EPHA5

1.61e-041841956a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATAD5 MCM6 ASPM LIG1 NEIL3 CARD11

1.66e-04185195657c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCelldroplet-Marrow-nan-18m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCG4 ST3GAL6 SLC43A3 MINPP1 CPOX LIG1

1.66e-041851956a45756f91b62cf0fac3582786e5868deb8fd8435
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ZGRF1 ELAPOR1 ASPM KIF14 NEIL3

1.66e-04185195630e041d6f6e310d64809e9d6d93cd30052972f3b
DrugCPG-oligonucleotide

SMG1 TREX1 SETX CCNO MLH1 RB1 ASTE1 CENPS LIG1 NEIL3 PRKDC

4.90e-0718419211ctd:C408982
DiseaseCharcot-Marie-Tooth disease type 2A2A (implicated_via_orthology)

MFN2 MFN1

4.04e-0521882DOID:0110155 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease type 2A2B (implicated_via_orthology)

MFN2 MFN1

4.04e-0521882DOID:0111557 (implicated_via_orthology)
Diseaselysophosphatidylethanolamine 18:0 measurement

KBTBD3 MATN2 FBXL7

1.09e-04151883EFO_0010367
DiseaseGastric Adenocarcinoma

TRRAP MLKL MLH1 EPHA10

1.94e-04451884C0278701
DiseaseCharcot-Marie-Tooth disease type 2 (implicated_via_orthology)

MFN2 MFN1

2.40e-0441882DOID:0050539 (implicated_via_orthology)
DiseaseDyggve-Melchior-Clausen disease (implicated_via_orthology)

RAB8B RAB8A

2.40e-0441882DOID:0111167 (implicated_via_orthology)
Diseasein situ carcinoma (is_marker_for)

PDGFRA RB1 POU5F1

3.11e-04211883DOID:8719 (is_marker_for)
DiseaseNeurodevelopmental Disorders

SRCAP KCNH1 DLG4 DSCAM ALG13

3.29e-04931885C1535926
Diseaseseminoma (is_marker_for)

PDGFRA RB1 POU5F1

3.59e-04221883DOID:4440 (is_marker_for)
DiseaseSmith-McCort dysplasia (implicated_via_orthology)

RAB8B RAB8A

3.99e-0451882DOID:0060247 (implicated_via_orthology)
Diseaseworry measurement

CTTNBP2 AREL1 DLST DRD2 DSCAM IGSF9B

4.75e-041541886EFO_0009589
DiseaseInvoluntary Movements

DRD2 GRIN1

8.30e-0471882C0427086
Diseaseembryonal carcinoma (is_marker_for)

RB1 POU5F1

8.30e-0471882DOID:3308 (is_marker_for)
Diseaseprimary pulmonary hypertension (is_marker_for)

MFN2 MFN1

1.10e-0381882DOID:14557 (is_marker_for)
DiseaseVasodilators used in cardiac diseases use measurement

DYNC2H1 RNF213 APOB

1.32e-03341883EFO_0009926
DiseaseAlzheimer's disease (is_marker_for)

UCP1 MFN2 DLG4 PLCD1 DRD2 GRIN1 MFN1

1.36e-032571887DOID:10652 (is_marker_for)
Diseaseage at menarche

RB1CC1 PTPRG PML CCDC170 DSCAM ZC3HC1 POU3F2 KBTBD2 CTBP2 PAN3 EPHA5

1.58e-0359418811EFO_0004703
Diseasevascular endothelial growth factor receptor 3 measurement

ST3GAL6 CPOX

1.76e-03101882EFO_0008315
Diseasequality of life during menstruation measurement, dysmenorrheic pain measurement

RB1CC1 VPS13B

2.14e-03111882EFO_0007889, EFO_0009366
Diseaseurate measurement, bone density

FBXL4 PTPRG KIF14 TAF4B AKAP6 DSCAM POU3F1 MINPP1 CCER1 PLXNC1 PRKDC

2.17e-0361918811EFO_0003923, EFO_0004531
DiseaseSclerocystic Ovaries

LARP4 ASPM DLG4 TNPO2 SPTBN4

2.34e-031441885C1136382
DiseasePolycystic Ovary Syndrome

LARP4 ASPM DLG4 TNPO2 SPTBN4

2.34e-031441885C0032460
Diseasefeeling nervous measurement

AREL1 DLST DSCAM POU3F2

2.35e-03871884EFO_0009597
Diseasemismatch repair cancer syndrome (is_implicated_in)

MLH1 ASTE1

2.56e-03121882DOID:0112182 (is_implicated_in)
Diseaseprediabetes syndrome (biomarker_via_orthology)

UCP1 MFN2

2.56e-03121882DOID:11716 (biomarker_via_orthology)
Diseasegait measurement

KIF14 IGSF3 AKAP6 DRD2 CTBP2

2.80e-031501885EFO_0007680
Diseaseleukemia (is_implicated_in)

PDGFRA BCR

3.01e-03131882DOID:1240 (is_implicated_in)
Diseasepulse pressure measurement

NEK6 PDGFRA CIB4 SRCAP LARP4 AREL1 FBXL7 PXDNL DSCAM DYNC2H1 RNF213 INTS8 CCDC197 SPTBN4 FAM13A PLXNC1 CSNK1G3 RNF207

3.56e-03139218818EFO_0005763
Diseasearm span

DSCAM POU3F2

4.01e-03151882EFO_0005108
DiseaseHypertriglyceridemia

APOB LIPI

4.01e-03151882C0020557
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

ASPM KIF14

4.57e-03161882DOID:0070296 (is_implicated_in)
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

BCR TLX1 TLX3

4.72e-03531883C1961099
Diseasetype 2 diabetes mellitus (is_implicated_in)

HK2 FOXA2 UCP1 DRD2 APOB

4.88e-031711885DOID:9352 (is_implicated_in)
Diseasehair morphology measurement

FBXL7 CPOX PLXNC1

4.97e-03541883EFO_0007821
Diseaseendometriosis

MROH5 KCNG2 CCDC170 COL12A1 PDE5A VPS13B

5.70e-032521886EFO_0001065
Diseasebipolar disorder, sex interaction measurement

TTC39B TLE4

5.78e-03181882EFO_0008343, MONDO_0004985

Protein segments in the cluster

PeptideGeneStartEntry
NCEAFTVTLISKDRL

PTPRG

1271

P23470
DFVTLLTANTCDIRK

ATAD5

1381

Q96QE3
FATSTLTQFCILFKR

ABCG4

366

Q9H172
SELTFRQCENFAKDL

CENPS

51

Q8N2Z9
TAKDASCLFRAISEQ

ALG13

236

Q9NP73
ESLRNCVNKEFFVTS

CTBP2

351

P56545
FESLCLTVNTLDRFL

CCNO

151

P22674
FALLRSCQEVFDKLA

B4GAT1

176

O43505
KKCFRSFSLTSVELQ

BCR

866

P11274
TIDSFQDAVKCLSEF

ARFGEF1

1316

Q9Y6D6
RIFDTCNTVSKALEA

CASR

96

P41180
IFIELKFTLRDCNSL

EPHA5

126

P54756
DLLCIAKTFSYLRES

CISH

66

Q9NSE2
FSLFEASQISKEICE

ANO9

216

A1A5B4
FTASQDTQKRLEAFC

CCDC197

86

Q8NCU1
LITRKDFETLFTDCT

DACH2

146

Q96NX9
SLEKNERACIDFAIS

CACNA1B

1431

Q00975
AEEKRENFISCTFLN

CCER1

371

Q8TC90
ASKEILLAFSRDFLS

ASPM

921

Q8IZT6
VLSSDSDFCIFDLKT

ASTE1

156

Q2TB18
NEESLRKVDSAVFCL

CPT2

311

P23786
DVLFALFSKLERTCE

RB1

156

P06400
KTCVLFRFSEDAFNS

RAB8A

21

P61006
KTCLLFRFSEDAFNT

RAB8B

21

Q92930
DFLLEVCSRSVNLEK

INTS8

416

Q75QN2
TESIDKRFCFDIETN

OPHN1

326

O60890
FLQVSFLSKACSDFL

KBTBD3

131

Q8NAB2
FNEESLLKSTNCFDI

KBTBD3

256

Q8NAB2
KLCSDFQEDIVFRFS

MFN1

511

Q8IWA4
RILKCSEQSLIEFFN

RBL2

116

Q08999
EKVVQLNSSFSLRCF

PDGFRA

36

P16234
SIQTIKEDLCHFRTF

RB1CC1

811

Q8TDY2
TNERLCVRFEFLSKL

IL17RA

121

Q96F46
CQKLFLDFLEEFQSS

MCM6

26

Q14566
LCERNDKVFFASVRS

MAP4K4

1206

O95819
LESLAKSLLFCFESE

KIF14

1571

Q15058
DSSLLNSEFCFILKV

FLII

1076

Q13045
CSSAFFEEERSALKQ

LIN9

176

Q5TKA1
CENKRADLVFIIDSS

MATN2

51

O00339
IEKLSSRFQETFCAL

MATN3

251

O15232
VNCSLFSAVREDFKD

MAF1

131

Q9H063
FKTALFETVCFASIL

NMUR2

121

Q9GZQ4
VQLTKDLICFFDSSV

NEIL3

121

Q8TAT5
TRFCTGLTQIETLFK

CKB

251

P12277
ECFFDLLTKFQSSRM

GPSM1

496

Q86YR5
NKEVARITFVFETLC

ELAPOR1

491

Q6UXG2
ECNLIFRLKDLDFAS

DDX55

436

Q8NHQ9
SDASRKSFVFELNEC

CCDC88C

446

Q9P219
KSFVFELNECASSRI

CCDC88C

451

Q9P219
IFETKFLSQIESDCL

HK2

781

P52789
RVSFTDFKETLIATC

CFAP52

316

Q8N1V2
VKDRCLFASFLTIAL

PLXNC1

1081

O60486
FEFLLRSLQAESKCA

KCNG2

231

Q9UJ96
ILSCSDTSIFEKILF

OR2M3

186

Q8NG83
ILSCNDTSIFEKVLF

OR2M5

186

A3KFT3
DVIKLACADTTFNRL

OR51B5

181

Q9H339
SLFLVCEDSSNDKFL

PDE5A

186

O76074
CEDSSNDKFLISRLF

PDE5A

191

O76074
TIEDTVRSCVAKLFF

VEPH1

576

Q14D04
LLSFADLFSCEELKQ

KBTBD2

136

Q8IY47
LSFRCSLADFQIEKK

NEK6

36

Q9HC98
TTICRFEALQLSFKN

POU3F1

291

Q03052
DKVVLFLCTFSDITA

KCNH1

121

O95259
FRCNSLSTLEKNDVV

LAMP2

151

P13473
IFVELQFTLRDCSSI

EPHA10

101

Q5JZY3
SLKFERCLDSEVVTF

NOL10

86

Q9BSC4
FSTCFTELQRDFLKQ

OAS1

186

P00973
TLKTDFSARCFLDQF

FAM13A

901

O94988
FIVECRAKQSISFFL

GPR55

256

Q9Y2T6
LFDLCDRTFSLKTVL

CSNK1G3

126

Q9Y6M4
IEKFSNRSNICRFLT

MLKL

76

Q8NB16
CRFLTASQDKILFKD

MLKL

86

Q8NB16
KFDCIIISDSNSVFI

PHOSPHO2

91

Q8TCD6
FTVKANRDCSFLSIS

PNPLA7

541

Q6ZV29
FERRFEECISQSAVK

MFN2

341

O95140
GKVFSQTTICRFEAL

POU5F1

176

Q01860
QTTICRFEALQLSFK

POU5F1

181

Q01860
LRKRFETTAVNTLFC

THAP12

216

O43422
CFSIVFKDQRNTLDL

PLCD1

96

P51178
FKFLLDRVSCLSEEL

SCYL3

271

Q8IZE3
KVSCEDTLFREFILF

OR9A1P

186

Q8NGU1
SVRFFRTTAVCKDDL

DLST

56

P36957
SDLKRCFENTFQELI

PAN3

866

Q58A45
FRVFCNLTSVKNFED

PXDNL

1156

A1KZ92
TFTDCTRFDALIKDV

DYNC2H1

1911

Q8NCM8
EKFDLRRFLCTESEQ

DYNC2H1

3236

Q8NCM8
AVLCEFISQSIKSFD

APOB

3191

P04114
EKAAFQLDCSIVSRS

IGSF3

966

O75054
ASCFFLLKQFDDVLI

TTC26

366

A0AVF1
FTVFQTLDKCNDIIR

HEATR5B

86

Q9P2D3
KRRIVFSSFDADICT

GPCPD1

496

Q9NPB8
LTVLDTISFFTQCFK

DOCK11

1406

Q5JSL3
RKSAAFQIQSFDIVC

COL12A1

2696

Q99715
FSKEQLLDLFISSAC

CTTNBP2

1166

Q8WZ74
QKLFLTANRSVCDTD

FBXL4

536

Q9UKA2
IKELSVSDCRFVSDF

FBXL7

326

Q9UJT9
LFACESAVKDFQSIL

C7orf25

301

Q9BPX7
FVKDEKTRFSLALEC

COPA

641

P53621
LTAAVFCLTQKFRAS

FRMPD1

1561

Q5SYB0
IFAFKCSRAEEIFNL

FRS3

86

O43559
EALLRCSDIISYTFK

GEMIN7

116

Q9H840
FELICKALFDTTNQL

AREL1

511

O15033
RATKLEQEFTECFSA

DLG4

676

P78352
QLEFCFSRENLSKDL

LARP4

126

Q71RC2
LADCLKAAQSRDFTV

LYPD6

16

Q86Y78
VIFRKFECANVNSLT

LYPD8

191

Q6UX82
IATSCSDKNLSIFDF

MAPKBP1

676

O60336
FEFSCSSLLSQVFVK

ITGA10

896

O75578
SDVFDNLIISLCKFT

GBF1

971

Q92538
FELCVKTLRIFVEAS

GBF1

1411

Q92538
FCTSAKDAFVILVEN

SLC44A1

511

Q8WWI5
RSELAATLVKFECAQ

CCDC170

46

Q8IYT3
KFSRIHCDIFVTLDV

DRD2

101

P14416
FTELLLAITNCEERF

CYLD

96

Q9NQC7
LAITNCEERFSLFKN

CYLD

101

Q9NQC7
SFCRLQTEKETLFND

GRIPAP1

241

Q4V328
RELLAKFFQSCADVL

FDXACB1

101

Q9BRP7
ISEVLKRFEEAAFTC

LIG1

551

P18858
CEFLSNIFQALTKET

SAAL1

401

Q96ER3
VSFFTNLLFCDDRKN

CFAP47

1391

Q6ZTR5
SKEEVFRFVQSCARA

CPOX

346

P36551
FTICKSDIVTRDEFL

CARD11

1001

Q9BXL7
EFDICFTSVQKRAIR

PGAM1

51

P18669
KLTLSGICEFISNRF

FOXD3

161

Q9UJU5
EISRCLFFVFSLTEK

IFNE

171

Q86WN2
LSFNKLSFISLELCV

LRRC40

456

Q9H9A6
ETDAEKLVQLTFCAF

CROT

586

Q9UKG9
SCNDFLFERKSIVSL

PRR14L

561

Q5THK1
FCLETFLSDLIAHQK

IRF6

346

O14896
KLACVDTTFNEAELF

OR2G6

186

Q5TZ20
ERKSQLLSTCFRSVF

MROH5

491

Q6ZUA9
SIRHSLSFNDCFLKV

FOXA2

206

Q9Y261
QLRHAKFTITECFIS

DSCAM

1826

O60469
YILCSDTRSQLKFLE

TAF4B

716

Q92750
SRKLLCTVFETLSDF

UTP20

1406

O75691
ICSSFLSLANKAEFL

RNF207

296

Q6ZRF8
KCTIFALASINEELF

TDRD6

921

O60522
RTSEAAIRCEFVKFQ

TDRD6

1441

O60522
FLDTCEFIIEIFSKS

PPP4R4

586

Q6NUP7
INRSVLDFDFEKLCS

USP39

111

Q53GS9
CLEFSQLSVKDSFRD

LIPI

21

Q6XZB0
TLQEITFSFCRLFEK

LRRC41

671

Q15345
DFFTKPSRLIQCFDT

KBTBD4

391

Q9NVX7
CSLKEIQLSTDKFFR

NSUN7

476

Q8NE18
CETFNDFVRLFKQVT

ORC5

96

O43913
FDEFKVRLQDLSSCI

PML

376

P29590
CSIEESFQRFDAILK

HMGCL

141

P35914
LQTIKEFFRLCGTFS

SMG1

3026

Q96Q15
IVNVKTLFRNSCFSE

SMG1

3061

Q96Q15
AISKFDDFSRDLCVQ

MED24

81

O75448
TEDVNCAFEFLLKLT

MED24

331

O75448
LLTLKDTFFDRAKAC

POLR3A

551

O14802
DTFFDRAKACQIIAS

POLR3A

556

O14802
LALSKLQSCDLFDEF

ST3GAL6

96

Q9Y274
QTDAVCDKVTEFFLL

SETX

446

Q7Z333
ADCKAQDERFSLIFT

SLC43A3

61

Q8NBI5
NADKRIFCFILSTRS

SRCAP

2106

Q6ZRS2
VCERFTTSKLQSFED

MLH1

76

P40692
TTICRFEALQLSFKN

POU3F2

306

P20265
KLSCNNTLFTEFILF

OR9A4

186

Q8NGU2
LFEAFAKVICNSFTI

SMYD3

171

Q9H7B4
RKFFETKLCQIFSDL

U2SURP

616

O15042
DTELFIFNSCLRQEK

AKAP6

1096

Q13023
VREKEDFIFTCNSRI

CCDC146

841

Q8IYE0
TFLTRNEILCIHDTF

CIB4

21

A0PJX0
TDASACKNILRFIQF

UFSP2

76

Q9NUQ7
ALSTISAFDRIDFAK

TMEM237

281

Q96Q45
AILVSEFLDRFQSLC

ZC3HC1

176

Q86WB0
FVCFEQLKRELSKSR

UCP1

286

P25874
NSFFVDLVSTICFKD

RNF213

4066

Q63HN8
FIISDLTIALNKFCF

TMEM86A

186

Q8N2M4
FLQEFKSTLSRCSNV

TRIM7

281

Q9C029
FNSFSVDDECLVKLL

TTC39B

576

Q5VTQ0
RVAFACKFLSDTQLN

MIOS

616

Q9NXC5
IQVAFFTCSFDLAIK

MINPP1

281

Q9UNW1
SEQFLTELTRLFQKC

SRP14

6

P37108
FTISESCDRIKEEFQ

TLE4

26

Q04727
AAILFSTLAACFVNK

IGSF9B

736

Q9UPX0
TCLKDQDLIFSAAFE

PSTK

116

Q8IV42
KRVQEAACSAFATLE

TNPO2

491

O14787
TFALDFSREKKLLEC

MID1

361

O15344
TFSLASSFRQEKILE

SUGP2

486

Q8IX01
KVVLAACSDFFRTKL

ZBTB44

46

Q8NCP5
ESKFLESLNCQTIRF

WDR72

206

Q3MJ13
CFNLSDDIRVAISKK

ZBED8

561

Q8IZ13
TAAASLFECSRIKAL

SPTBN4

41

Q9H254
QSETSCFKRQLVFLE

TAS1R2

546

Q8TE23
AFCKTLTRTLLTFFD

SMIM10

41

Q96HG1
TSFSRVQICELEKRF

TLX3

171

O43711
DIITNRCFFLSKIEE

PRKDC

3181

P78527
TSFTRLQICELEKRF

TLX1

206

P31314
FKFASVFRLLTLDSE

TSPAN18

156

Q96SJ8
KSCRTITFEQFQEAL

TPPP

106

O94811
VAFREFNLSESKVCE

VPS13B

2391

Q7Z7G8
SKTLDFELDTFIACS

ZGRF1

1486

Q86YA3
KCLEDRGFFILLTSS

TASOR2

121

Q5VWN6
SSEEFSTKFNLICRE

TEX15

531

Q9BXT5
ACFDVSSVIQKNLRF

THAP10

61

Q9P2Z0
NRLDSVACDVLFSKL

UBR4

946

Q5T4S7
KNVFRLTTSDCECLF

ARHGAP21

1006

Q5T5U3
FCVDSITALKALERA

TREX1

151

Q9NSU2
FTLERFSLNTVELVC

UNC5C

781

O95185
IEEKCRFLSNFSAQT

TRRAP

3461

Q9Y4A5
FKFFTDLVNRCLVTV

ZFC3H1

1806

O60293
LCSIFTEHKDIFSRE

ZNF736

156

B4DX44
RQKLVTSFCRSDFVI

WFIKKN2

451

Q8TEU8
SFTFVERSKQECFLN

VPS13D

1271

Q5THJ4
VFKTEFVSLLCKRFE

MYO1F

846

O00160
SQKCDLVTTGELFFR

GRIN1

741

Q05586