Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RIN1 PSD PLEKHG6 ARHGEF17 DENND2B TIAM2 PSD4	2.16e-05	231	73	7	GO:0005085
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RIN1 PSD PLEKHG6 ARHGAP30 ARHGEF17 DENND2B TIAM2 PSD4	5.17e-04	507	73	8	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RIN1 PSD PLEKHG6 ARHGAP30 ARHGEF17 DENND2B TIAM2 PSD4	5.17e-04	507	73	8	GO:0030695
Domain	-	PSD PLEKHG6 PLEKHM2 PLEKHF1 FRMPD2 APBB3 ARHGEF17 TIAM2 PLEKHH3 PSD4	2.13e-06	391	71	10	2.30.29.30
Domain	PH_dom-like	PSD PLEKHG6 PLEKHM2 PLEKHF1 FRMPD2 APBB3 ARHGEF17 TIAM2 PLEKHH3 PSD4	4.57e-06	426	71	10	IPR011993
Domain	PH	PSD PLEKHG6 PLEKHM2 PLEKHF1 TIAM2 PLEKHH3 PSD4	8.85e-05	278	71	7	SM00233
Domain	PH_DOMAIN	PSD PLEKHG6 PLEKHM2 PLEKHF1 TIAM2 PLEKHH3 PSD4	9.05e-05	279	71	7	PS50003
Domain	PH_domain	PSD PLEKHG6 PLEKHM2 PLEKHF1 TIAM2 PLEKHH3 PSD4	9.26e-05	280	71	7	IPR001849
Domain	Peptidase_S8_Asp-AS	FURIN PCSK4	2.12e-04	6	71	2	IPR023827
Domain	PrprotnconvertsP	FURIN PCSK4	2.96e-04	7	71	2	IPR002884
Domain	P_proprotein	FURIN PCSK4	2.96e-04	7	71	2	PF01483
Domain	S8_pro-domain	FURIN PCSK4	2.96e-04	7	71	2	IPR032815
Domain	-	FURIN PCSK4	2.96e-04	7	71	2	3.30.70.850
Domain	S8_pro-domain	FURIN PCSK4	2.96e-04	7	71	2	PF16470
Domain	Peptidase_S8_His-AS	FURIN PCSK4	5.04e-04	9	71	2	IPR022398
Domain	PH_dom-spectrin-type	PSD PSD4	5.04e-04	9	71	2	IPR001605
Domain	Peptidase_S8_Ser-AS	FURIN PCSK4	5.04e-04	9	71	2	IPR023828
Domain	Peptidase_S8_subtilisin-rel	FURIN PCSK4	6.29e-04	10	71	2	IPR015500
Domain	SUBTILASE_ASP	FURIN PCSK4	6.29e-04	10	71	2	PS00136
Domain	SUBTILASE_HIS	FURIN PCSK4	6.29e-04	10	71	2	PS00137
Domain	SUBTILASE_SER	FURIN PCSK4	6.29e-04	10	71	2	PS00138
Domain	-	FURIN PCSK4	7.66e-04	11	71	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	FURIN PCSK4	7.66e-04	11	71	2	IPR000209
Domain	Peptidase_S8	FURIN PCSK4	7.66e-04	11	71	2	PF00082
Domain	-	PSD PSD4	1.45e-03	15	71	2	1.10.1000.11
Domain	Sec7	PSD PSD4	1.45e-03	15	71	2	PF01369
Domain	Sec7_alpha_orthog	PSD PSD4	1.45e-03	15	71	2	IPR023394
Domain	Sec7	PSD PSD4	1.65e-03	16	71	2	SM00222
Domain	SEC7	PSD PSD4	1.65e-03	16	71	2	PS50190
Domain	Sec7_dom	PSD PSD4	1.65e-03	16	71	2	IPR000904
Domain	DH_1	PLEKHG6 ARHGEF17 TIAM2	1.78e-03	63	71	3	PS00741
Domain	PH	PSD PLEKHM2 PLEKHF1 TIAM2 PSD4	1.79e-03	229	71	5	PF00169
Domain	Propept_inh	FURIN PCSK4	1.87e-03	17	71	2	IPR009020
Domain	PDZ	FRMPD2 TIAM2 AHNAK2 TJP3	2.04e-03	141	71	4	PF00595
Domain	Furin_repeat	FURIN PCSK4	2.10e-03	18	71	2	IPR006212
Domain	FU	FURIN PCSK4	2.10e-03	18	71	2	SM00261
Domain	RhoGEF	PLEKHG6 ARHGEF17 TIAM2	2.21e-03	68	71	3	SM00325
Domain	RhoGEF	PLEKHG6 ARHGEF17 TIAM2	2.40e-03	70	71	3	PF00621
Domain	DH_2	PLEKHG6 ARHGEF17 TIAM2	2.40e-03	70	71	3	PS50010
Domain	PDZ	FRMPD2 TIAM2 AHNAK2 TJP3	2.44e-03	148	71	4	SM00228
Domain	DH-domain	PLEKHG6 ARHGEF17 TIAM2	2.50e-03	71	71	3	IPR000219
Domain	-	PLEKHG6 ARHGEF17 TIAM2	2.50e-03	71	71	3	1.20.900.10
Domain	-	FRMPD2 TIAM2 AHNAK2 TJP3	2.56e-03	150	71	4	2.30.42.10
Domain	PDZ	FRMPD2 TIAM2 AHNAK2 TJP3	2.62e-03	151	71	4	PS50106
Domain	PDZ	FRMPD2 TIAM2 AHNAK2 TJP3	2.68e-03	152	71	4	IPR001478
Domain	RA	RIN1 PLEKHH3	8.26e-03	36	71	2	PF00788
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	B4GALNT4 PLEKHM2 SPEG FURIN ZNF316 SEC16A APBB3 AKNA LMTK2 RNF43 TIAM2 PLEKHH3 AHNAK2 TJP3	6.35e-08	1105	73	14	35748872
Pubmed	Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization.	FURIN PCSK4	4.35e-06	2	73	2	8422932
Pubmed	USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly.	PSD PSD4	1.30e-05	3	73	2	20339350
Pubmed	Private rare deletions in SEC16A and MAMDC4 may represent novel pathogenic variants in familial axial spondyloarthritis.	SEC16A MAMDC4	1.30e-05	3	73	2	25956157
Pubmed	Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides.	FURIN PCSK4	2.60e-05	4	73	2	10701998
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 MAP1A WEE1 AP5B1 DDN KMT2E APOBR	3.39e-05	430	73	7	35044719
Pubmed	Control mechanism of the circadian clock for timing of cell division in vivo.	WEE1 CRY1	4.33e-05	5	73	2	12934012
Pubmed	The new enzymology of precursor processing endoproteases.	FURIN PCSK4	4.33e-05	5	73	2	1429684
Pubmed	EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis.	PSD PSD4	4.33e-05	5	73	2	23603394
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PRUNE2 SEC16A ARHGEF17 ZNF646	7.01e-05	104	73	4	9205841
Pubmed	Proteolytic processing in the secretory pathway.	FURIN PCSK4	9.06e-05	7	73	2	10409610
Pubmed	The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.	FURIN PCSK4	9.06e-05	7	73	2	7819324
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCAF8 PSD MAP1A WEE1 BRPF1 ZNF316 TNRC6A SEC16A RNF43 ZNF646	1.10e-04	1116	73	10	31753913
Pubmed	Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.	FURIN PCSK4	1.21e-04	8	73	2	7782070
Pubmed	Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.	FURIN PCSK4	1.21e-04	8	73	2	9885250
Pubmed	The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions.	FURIN PCSK4	1.55e-04	9	73	2	23775089
Pubmed	The activation and physiological functions of the proprotein convertases.	FURIN PCSK4	1.55e-04	9	73	2	18343183
Pubmed	SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.	FURIN PCSK4	1.55e-04	9	73	2	8698813
Pubmed	The prohormone theory and the proprotein convertases: it is all about serendipity.	FURIN PCSK4	1.55e-04	9	73	2	21805236
Pubmed	The proprotein convertases, 20 years later.	FURIN PCSK4	1.55e-04	9	73	2	21805237
Pubmed	The biology and therapeutic targeting of the proprotein convertases.	FURIN PCSK4	1.55e-04	9	73	2	22679642
Pubmed	Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1).	WEE1 DENND2B	1.93e-04	10	73	2	11528126
Pubmed	Distinct spatiotemporal expression of EFA6D, a guanine nucleotide exchange factor for ARF6, among the EFA6 family in mouse brain.	PSD PSD4	1.93e-04	10	73	2	16707115
Pubmed	Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.	FURIN PCSK4	1.93e-04	10	73	2	16163737
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PLEKHM2 SPEG PDE4DIP SEC16A DDN ARHGEF17	2.18e-04	407	73	6	12693553
Pubmed	HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.	STRN ZRANB1	3.34e-04	13	73	2	23277359
Pubmed	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.	PDE4DIP CEP164	3.34e-04	13	73	2	17920017
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF13B WEE1 CEP95 SEC16A LMTK2 ARHGEF17 DENND2B AHNAK2	4.44e-04	861	73	8	36931259
Pubmed	Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.	DLL3 NKX3-2	4.48e-04	15	73	2	19520072
Pubmed	Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7.	WEE1 DENND2B	5.12e-04	16	73	2	11528127
Pubmed	Identification and characterization of proteins interacting with Traf4, an enigmatic p53 target.	PDE4DIP YJEFN3	5.12e-04	16	73	2	16969126
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	STRN DCAF8 PDE4DIP ZNF316 SHMT2 PLEKHH3 ZNF646	6.10e-04	689	73	7	36543142
Pubmed	A crucial role for Arf6 in the response of commissural axons to Slit.	PSD PSD4	7.26e-04	19	73	2	30674481
Pubmed	Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism.	DCAF8 CRY1	8.06e-04	20	73	2	31155351
Pubmed	Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.	DLL3 NKX3-2	9.77e-04	22	73	2	21750033
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MAP1A TNRC6A SEC16A DDHD2	9.97e-04	209	73	4	36779422
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	STRN DCAF8 TASOR ZRANB1	1.05e-03	212	73	4	33853758
Pubmed	Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.	TGFBR3 DLL3	1.07e-03	23	73	2	14701881
Pubmed	Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity.	PDE4DIP SEC16A	1.07e-03	23	73	2	22792062
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ERICH1 PLEKHM2 FURIN TNRC6A SEC16A TJAP1 TASOR	1.23e-03	777	73	7	35844135
Pubmed	The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.	TGFBR3 FURIN DLL3	1.24e-03	100	73	3	24859004
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	WEE1 ARHGEF17 DENND2B	1.31e-03	102	73	3	15778465
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	LMTK2 TASOR CEP164	1.39e-03	104	73	3	10470851
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KIF13B STRN MAP1A WEE1 TNRC6A SEC16A	1.49e-03	588	73	6	38580884
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	PLEKHM2 PDE4DIP AKNA KMT2E	1.49e-03	233	73	4	37704626
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	DCAF8 MAP1A CEP95 SURF2 FURIN PDE4DIP BSCL2 TMBIM1 TIAM2	1.51e-03	1293	73	9	15342556
Interaction	RAPGEFL1 interactions	PLEKHG6 SHMT2 ARHGAP30 ARHGEF17	3.14e-06	29	71	4	int:RAPGEFL1
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD PLEKHG6 PLEKHM2 PLEKHF1 TIAM2 PLEKHH3 PSD4	8.27e-07	206	46	7	682
GeneFamily	Proprotein convertase subtilisin/kexin family	FURIN PCSK4	2.25e-04	9	46	2	973
GeneFamily	PDZ domain containing	FRMPD2 TIAM2 AHNAK2 TJP3	5.95e-04	152	46	4	1220
Drug	Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A	PRUNE2 STRN DCAF8 PDE4DIP NKX3-2 TJAP1 DENND2B ZNF646	2.26e-07	197	73	8	1695_UP
Drug	Enalapril maleate [76095-16-4]; Up 200; 8.2uM; HL60; HT_HG-U133A	PRUNE2 KIF13B SPEG TMBIM1 AKAP7 TJP3 ZNF646	3.39e-06	198	73	7	2397_UP
Drug	Lidoflazine [3416-26-0]; Down 200; 8.2uM; PC3; HT_HG-U133A	RIN1 STRN PDE4DIP NKX3-2 TJAP1 ARHGEF17 AKAP7	3.51e-06	199	73	7	5804_DN
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	TGFBR3 STRN PLEKHM2 PDE4DIP RNF43 AKAP7 TJP3	3.51e-06	199	73	7	5535_DN
Drug	irinotecan HCl; Up 200; 100uM; MCF7; HT_HG-U133A	RIN1 MAP1A PLEKHF1 NKX3-2 RHBDL1 DDN	2.88e-05	185	73	6	7498_UP
Drug	Methocarbamol [532-03-6]; Down 200; 16.6uM; PC3; HT_HG-U133A	PLEKHM2 FURIN PLEKHF1 PDE4DIP TMBIM1 TJP3	3.75e-05	194	73	6	2111_DN
Drug	Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A	STRN PLEKHG6 PLEKHF1 ARHGEF17 AKAP7 PSD4	3.97e-05	196	73	6	3892_DN
Drug	Aminophylline [317-34-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A	TGFBR3 STRN FURIN PLEKHF1 CEP164 AHNAK2	3.97e-05	196	73	6	3374_DN
Drug	Anabasine [494-52-0]; Up 200; 24.6uM; MCF7; HT_HG-U133A	TGFBR3 RIN1 PLEKHM2 PDE4DIP TJAP1 ARHGEF17	3.97e-05	196	73	6	6774_UP
Drug	Flecainide acetate [54143-56-5]; Down 200; 8.4uM; HL60; HT_HG-U133A	PLEKHG6 FURIN CEP164 TMBIM1 TJP3 PSD4	4.09e-05	197	73	6	2557_DN
Drug	Scoulerine [6451-73-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	DCAF8 PLEKHM2 WEE1 FURIN PDE4DIP RNF43	4.09e-05	197	73	6	5536_DN
Drug	Chlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	RIN1 PLEKHM2 PDE4DIP ARHGEF17 TJP3 PSD4	4.21e-05	198	73	6	6800_UP
Drug	Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A	TGFBR3 DCAF8 BRPF1 ARHGEF17 RNF43 AKAP7	4.33e-05	199	73	6	3574_DN
Drug	Zomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; HL60; HT_HG-U133A	KIF13B STRN PLEKHF1 PDE4DIP AKAP7 PSD4	4.33e-05	199	73	6	2713_DN
Drug	Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	RIN1 STRN DCAF8 NKX3-2 CEP164 AKAP7	4.33e-05	199	73	6	4708_DN
Disease	hypertension	HOXB-AS3 FURIN KLF14 DDHD2 RNF43	9.34e-04	307	72	5	EFO_0000537
Disease	alcohol use disorder (implicated_via_orthology)	PSD RHBDL1 SHMT2 PSD4	1.34e-03	195	72	4	DOID:1574 (implicated_via_orthology)
Disease	cutaneous squamous cell carcinoma	WEE1 SEC16A	2.95e-03	33	72	2	EFO_1001927

Protein segments in the cluster

Peptide	Gene	Start	Entry
GTTDFESPEAGGWED	MAMDC4	491	Q6UXC1
ESPEAGGWEDASVGR	MAMDC4	496	Q6UXC1
PTWAGEEEGADSGEE	ERICH1	306	Q86X53
SWSSGEKNGGEPDDA	AKAP7	36	O43687
RETEPDGGSGWTKTQ	HTR3C	396	Q8WXA8
GDWSSEGCSTEVRPE	ADGRG3	226	Q86Y34
EGSGDGPSSSVDWNR	DLL3	551	Q9NYJ7
EKREGSGSEWAASEG	DENND2B	186	P78524
SDGSDTEAPGASWRN	DDN	641	O94850
TPERGAWESDAGPSD	ADAMTS20	111	P59510
RGWTGQESLSDSDPE	SHMT2	41	P34897
RWSGGPGLREEDTDT	ARHGEF17	21	Q96PE2
DGSDQGSWSPADCRG	LDLRAD2	201	Q5SZI1
EERAVSDSFGPGEWD	TMBIM1	76	Q969X1
EADSWGDTKRTPGVG	MAP1A	1026	P78559
SEEAPGVAWSGSESG	HOXB-AS3	31	C0HLZ6
SASWGPEDDGRTVDG	PCSK4	256	Q6UW60
GPGTFESWRSDSDVV	MUC19	701	Q7Z5P9
WREPGVGATDADSDE	DCAF8	561	Q5TAQ9
AGSDDWGSTPTEQGR	DDHD2	176	O94830
EIDPSSDGSNFGWET	KMT2E	261	Q8IZD2
SESSTDEEGGGFEWD	LMTK2	1406	Q8IWU2
SWPAAEEGEGERSLT	AP5B1	241	Q2VPB7
GTPGSSEEDEDTTWT	MEIOSIN	486	C9JSJ3
ADSAGESPWESSGEE	PLEKHG6	701	Q3KR16
AGRTAESPEGWDSDS	NKX3-2	81	P78367
DLSTPDPSEEWGSGD	NPAS4	716	Q8IUM7
WELGDAEDPGTGTEG	APBB3	61	O95704
EDSWRDSASPDAGEG	FRMPD2	1206	Q68DX3
SASWGPEDDGKTVDG	FURIN	251	P09958
DTDGLSSAVWPGGET	CRY1	201	Q16526
PSDSLDSTWEGETDG	AKNA	211	Q7Z591
LGPSWDGDEAESTGE	CEP95	166	Q96GE4
SGEGSWENSGEAPRA	KLF14	96	Q8TD94
QGPGSDWTERSSSAE	FAM216A	21	Q8WUB2
LEPEASDGSGSWEDA	BSCL2	341	Q96G97
STEWDLGGFSEPDSE	KBTBD6	641	Q86V97
SSSSEPEWVGAEDGE	ARHGAP30	516	Q7Z6I6
WEDGDLTDTVSGPRS	PLEKHM2	236	Q8IWE5
PEAGGWDATLTGEEE	KIF13B	1191	Q9NQT8
EDKEGSRDGDWPSSV	PLEKHF1	251	Q96S99
EGDNESRSAGDGTDW	STRN	296	O43815
WPETQGAVTEEEGSG	RIN1	706	Q13671
AAEEAGLEDSPDSGW	PLEKHH3	476	Q7Z736
PGSEWDGSTPSEDSR	PRUNE2	2031	Q8WUY3
SSAADGPWTQRGEEE	PSD	471	A5PKW4
SGEDSSEPEGEGQAW	PSD4	211	Q8NDX1
GEGPSEWSSDTAEGR	RNF43	741	Q68DV7
WEPTSSDEGGAASDD	SURF2	151	Q15527
DGGTTEELEDWDPGT	RHBDL1	6	O75783
WTSSDRGVDSPGGAG	FAM110D	211	Q8TAY7
QPTDASWESGGGGDD	TASOR	11	Q9UK61
GAGWLSEDEDSPLDA	BRPF1	1071	P55201
SEDSEEAAGPALGRW	B4GALNT4	661	Q76KP1
PWGDSLEETGAATGS	AHNAK2	361	Q8IVF2
EEAGTASGGDEAWTT	APOBR	361	Q0VD83
PWGGRVEAEESAGAE	APOBR	836	Q0VD83
WEEASDEGTLGGSPT	CEP164	1201	Q9UPV0
WEEESGFRREGSSGP	CILP2	691	Q8IUL8
ATEGESQEDWGGPTE	SLC7A14	711	Q8TBB6
TEEGPGTSHTEGRAW	TJAP1	506	Q5JTD0
GDSWEEEGFGSSSPV	WEE1	111	P30291
DSPWGNAGELSEAEG	TIAM2	251	Q8IVF5
AGDVWGDTASTGVPD	SEC16A	436	O15027
HPAWEARGGDGESSE	SPEG	2426	Q15772
EDGADGWGPSTNSAR	ZNF646	181	O15015
SGWDAETGSDSEDGL	YJEFN3	231	A6XGL0
EGPASWREGRGASSS	ZNF786	321	Q8N393
DGDSSSGSGRSWDER	TJP3	131	O95049
GTWGPDDSDSAQTPE	ZNF316	281	A6NFI3
GGSDSDRSVSGWNEL	TNRC6A	876	Q8NDV7
SSDVGRDWDPSSTEG	ZRANB1	46	Q9UGI0
GDSSGWPDGYEDLES	TGFBR3	531	Q03167
DSDSDWDGGSRLSPF	TMEM91	76	Q6ZNR0
SVPDEDEGWLSDGTG	PDE4DIP	1411	Q5VU43