Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransition metal ion binding

MYCBP2 ZSWIM5 SF3A2 RIOX1 SEC24A APOBEC1

8.27e-041189206GO:0046914
GeneOntologyMolecularFunctionzinc ion binding

MYCBP2 ZSWIM5 SF3A2 SEC24A APOBEC1

1.55e-03891205GO:0008270
GeneOntologyMolecularFunctionenzyme regulator activity

TBXA2R ELP3 MYCBP2 CCAR2 APOBEC1 ARHGAP39

2.07e-031418206GO:0030234
GeneOntologyBiologicalProcesspositive regulation of synapse maturation

NRXN1 ADGRL1

3.60e-0510192GO:0090129
MousePhenodecreased synaptic glutamate release

NRXN1 ADGRL1

2.60e-058142MP:0004495
MousePhenoabnormal synaptic glutamate release

NRXN1 ADGRL1

7.22e-0513142MP:0004494
MousePhenodecreased neurotransmitter release

NRXN1 ADGRL1

2.54e-0424142MP:0003990
Pubmed

Genetic analysis of alpha-latrotoxin receptors reveals functional interdependence of CIRL/latrophilin 1 and neurexin 1 alpha.

NRXN1 ADGRL1

3.47e-07221211741895
Pubmed

Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints.

TBXA2R SF3A2

2.04e-043521210984455
Pubmed

Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity.

NRXN1 MYCBP2

3.24e-044421222645275
Pubmed

A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.

MYCBP2 CCAR2

3.24e-044421226471122
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ELP3 MYCBP2 CCAR2 SEC24A ARHGAP39

3.36e-04104921527880917
Pubmed

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.

NRXN1 ADGRL1

4.52e-045221224613359
CytobandEnsembl 112 genes in cytogenetic band chr8p21

ELP3 CCAR2 R3HCC1

3.18e-05135213chr8p21
Cytoband19p13.3

TBXA2R SF3A2

5.22e-0323721219p13.3
CytobandEnsembl 112 genes in cytogenetic band chr19p13

TBXA2R ADGRL1 SF3A2

5.49e-03797213chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHA13 SEC24A

8.13e-03298212chr5q31
CytobandEnsembl 112 genes in cytogenetic band chr22q13

CHKB PNPLA5

9.88e-03330212chr22q13
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 ZSWIM5 CCAR2

8.34e-051832132f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 ZSWIM5 CCAR2

8.34e-051832130f02136359787bd78146617990968baa47a65d86
ToppCellfacs-Heart-RA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 ZSWIM5 CCAR2

9.32e-05190213bfbdf16d488359d7935a419c4c1823288f39c183
ToppCellfacs-Heart-RA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 ZSWIM5 CCAR2

9.32e-05190213eb1f8bb4d903b08e50c2dc173b06c0c79d8e316e
ToppCellfacs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 NTMT2 CCAR2

9.47e-051912138e06cc61eaff1796c2ce014074029408ba88d561
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 NTMT2 CCAR2

9.47e-05191213501d4f6ad389d9ac5051d4247b9bd3da96f713f9
Drugalpha-latrotoxin

NRXN1 ADGRL1

4.86e-064212ctd:C020763
Drugblack widow spider venom

NRXN1 ADGRL1

4.86e-064212ctd:C038599
DrugVerapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; PC3; HT_HG-U133A

TBXA2R ELP3 ADGRL1 SEC24A

2.96e-051982146287_DN
DiseaseMyopia

CHKB NRXN1 FER1L4

2.46e-03385213HP_0000545
DiseaseAbnormality of refraction

PCDHA13 CCAR2 FER1L4

1.16e-02673213HP_0000539

Protein segments in the cluster

PeptideGeneStartEntry
PRRLQTVVVYLPDVW

CCAR2

416

Q8N163
RRIEPWEFDVFYDPR

APOBEC1

16

P41238
PELFCEPREVRRVQW

ADGRL1

476

O94910
WRRVQPEELRVYPVS

CHKB

61

Q9Y259
PLYVPRVLRRQEEWG

R3HCC1

136

Q9Y3T6
ERYPERQLPWVQTRL

ARHGAP39

901

Q9C0H5
RQRIPYRLGRVVDEW

NRXN1

216

P58400
PRQPISYELRVVIWN

FER1L4

1486

A9Z1Z3
DIVYSFRRPVWPAVV

PCDHA13

276

Q9Y5I0
VPPWTRVYRVQRDIP

ELP3

356

Q9H9T3
IQRRFPTWTPDQYLR

LYG1

141

Q8N1E2
EFTPPFRRYDVIWIQ

NTMT2

176

Q5VVY1
RKQPEYWFAVPRERV

NCOA7

686

Q8NI08
WLREQRPFFPILYVI

SEC24A

1041

O95486
YFRSRRLVVWLPDVP

PNPLA5

356

Q7Z6Z6
DPVYDVIWRFRPNTR

MYCBP2

1131

O75592
EQRIEPPDRRWQYLL

SF3A2

156

Q15428
LWRVYRPRVPTEELA

RIOX1

356

Q9H6W3
DLLIYPWPELRRRQV

RPP38-DT

96

Q8N326
FERIPEPVQRRIVYW

ZSWIM5

86

Q9P217
EPVQRRIVYWSFPRN

ZSWIM5

91

Q9P217
QILDPWVYILFRRAV

TBXA2R

301

P21731