Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainC2H2_Znf_fam

ZNF202 ZNF641

8.66e-0424342IPR027775
DomainVWC

CHRDL1 CRIM1

1.18e-0328342PF00093
DomainVWFC_1

CHRDL1 CRIM1

1.95e-0336342PS01208
DomainVWC

CHRDL1 CRIM1

2.17e-0338342SM00214
DomainVWFC_2

CHRDL1 CRIM1

2.17e-0338342PS50184
DomainVWF_dom

CHRDL1 CRIM1

2.65e-0342342IPR001007
DomainKRAB

ZNF10 ZNF202 ZKSCAN5 ZNF641

3.91e-03358344PS50805
DomainKRAB

ZNF10 ZNF202 ZKSCAN5 ZNF641

3.91e-03358344PF01352
DomainKRAB

ZNF10 ZNF202 ZKSCAN5 ZNF641

4.35e-03369344SM00349
DomainKRAB

ZNF10 ZNF202 ZKSCAN5 ZNF641

4.40e-03370344IPR001909
DomainFN3

FLNC ANOS1 LRFN1

4.57e-03185343SM00060
DomainSCAN

ZNF202 ZKSCAN5

4.66e-0356342SM00431
DomainSCAN_BOX

ZNF202 ZKSCAN5

4.99e-0358342PS50804
DomainSCAN

ZNF202 ZKSCAN5

4.99e-0358342PF02023
DomainSCAN_dom

ZNF202 ZKSCAN5

4.99e-0358342IPR003309
DomainRetrov_capsid_C

ZNF202 ZKSCAN5

5.16e-0359342IPR008916
DomainFN3_dom

FLNC ANOS1 LRFN1

6.40e-03209343IPR003961
Pubmed

K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.

IRF1 SPHK1

2.74e-05835224464131
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FOCAD TRIOBP ZNF202 YY1AP1 CRIM1 CCDC24 ZKSCAN5

2.51e-04128535735914814
Pubmed

The human and mouse receptors for hyaluronan-mediated motility, RHAMM, genes (HMMR) map to human chromosome 5q33.2-qter and mouse chromosome 11.

IRF1 THRA

3.40e-04273528595891
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOCAD FLNC MRPL21 LRFN1 SPHK1 TMEM132A

7.48e-04110535635748872
Pubmed

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ.

ITGA8 TRIOBP

7.49e-044035227197753
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF10 ZNF202 ZKSCAN5 ZNF641

3.88e-0371817428
GeneFamilyFibronectin type III domain containing

ANOS1 LRFN1

9.70e-03160172555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRFN1 HMCN2

9.82e-03161172593
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

TRIOBP CHRDL1 FLNC SPHK1 GRAP

4.46e-07197355a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIOBP CHRDL1 FLNC SPHK1

1.01e-0517335485083b9ce20351dd69aa2327ad087b848b4307ff
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

CHRDL1 FLNC SPHK1 GRAP

1.08e-05176354b288116a4588a1f9db9d49af92cea118937c9201
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHRDL1 SPHK1 CYP8B1 GRAP

1.15e-0517935435fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHRDL1 SPHK1 CYP8B1 GRAP

1.15e-05179354ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL1 FLNC SPHK1 GRAP

1.26e-05183354764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL2 GPR12 CCDC24 ZNF641

1.26e-05183354bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL2 GPR12 CCDC24 ZNF641

1.26e-051833544c325ee6da070513097a11445ec95b0415ffd8a2
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|tumor_Lung / Location, Cell class and cell subclass

TRIOBP FLNC SPHK1 GRAP

1.37e-0518735487ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

ITGA8 HMCN2 CRIM1 STK38L

1.40e-0518835434e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellEndothelial-B|World / lung cells shred on cell class, cell subclass, sample id

CHRDL1 FLNC SPHK1 GRAP

1.40e-051883545959a88728812a5f4cbfa54eddc7a73ccbaa2f68
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ITGA8 HMCN2 CRIM1 STK38L

1.43e-051893546b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEM6 FLNC SPHK1 GRAP

1.46e-05190354b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1 GRAP

1.52e-05192354291df12b4b5ff11fbaa43033692b8f4b5cdf65a1
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1 GRAP

1.52e-0519235435ffe7aa9ffab85eac3326651e901c39d0119650
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CHRDL1 FLNC SPHK1 GRAP

1.58e-05194354640ff8da7084a9486fc2752493b8d8059ecf4ab7
ToppCellASK440-Endothelial-Lymphatic|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

CHRDL1 FLNC SPHK1 GRAP

1.58e-051943544aa68e39e36094359dfbedf1e9bdf3ea5c32ed1a
ToppCellcellseq-Endothelial-Endothelial_Lymphatic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHRDL1 FLNC SPHK1 GRAP

1.61e-05195354d8f01746c8f92532bd1a5c1b0bbb86208d64c3cd
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1 GRAP

1.61e-051953548f3b455553215f6e191842a5953a79c606f22c08
ToppCellcellseq-Endothelial-Endothelial_Lymphatic-LEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHRDL1 FLNC SPHK1 GRAP

1.61e-05195354918b68a271a81202778714e10b09c5c724575b73
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1 GRAP

1.61e-051953540ff59b073b88fab1f6ed98508714cab430c7d079
ToppCellcellseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHRDL1 FLNC SPHK1 GRAP

1.61e-051953548321531bb976e5005973b82f32177be88113abb3
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL1 FLNC SPHK1 GRAP

1.61e-0519535436d4a11bc77a4cc97a22525c78ef8359f4a3ca66
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1 GRAP

1.61e-051953547e71b1707b34ce47fffadf6f64d9554768221fc6
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1 GRAP

1.61e-051953543ea2b5ecb66faddeefffbf0d39fc7cb5abf35ad7
ToppCellfacs-Mammary_Gland|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC KCTD11 SPHK1 TMEM132A

1.61e-0519535421cfcb751e548591fc8724a8329c294da6012e0f
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA8 FLNC HMCN2 STK38L

1.68e-05197354bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCelldistal-3-Endothelial-Lymphatic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 FLNC SPHK1 GRAP

1.68e-051973549ea0e2ed9c3f97591a06e70570640996580417d5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC ANOS1 HMCN2 STK38L

1.68e-051973545a63c2b824c7d0dbbc706e408459c9b9fe65daaa
ToppCelldistal-Endothelial-Lymphatic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRDL1 FLNC SPHK1 GRAP

1.68e-051973548f2e19409ebe9a490d5a245fa82c765ed6d77c3e
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC SPHK1 CYP8B1 GRAP

1.71e-051983549ab0db78394e730f6866b2db80047149024ad5f6
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC SPHK1 CYP8B1 GRAP

1.71e-05198354e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellParenchyma_COVID-19-Endothelial-TX-Lymphatic|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

FLNC CRIM1 SPHK1 GRAP

1.75e-0519935488f33b8dcd837abfa1d12c28719e073a7da6e979
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLNC CRIM1 SPHK1 GRAP

1.75e-0519935464b19aff72e2a109cb5857cb248bd4712dd49b43
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLNC CRIM1 SPHK1 GRAP

1.75e-051993542b9e1e069b36b3a61cc3e384f4523687b0e03905
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TRIOBP FLNC SPHK1 GRAP

1.78e-0520035476e90231aa94afc12e618da8ae314c51644acab4
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TRIOBP FLNC SPHK1 GRAP

1.78e-05200354e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 CHRDL1 GPR12

2.61e-041593535ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ITGA8 CRIM1 SEC14L5

2.66e-041603530293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ITGA8 CRIM1 SEC14L5

2.66e-041603533eaae86fa08f7651021316f8e5811bf48055591e
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC FAM228A HMCN2

2.66e-041603538624f101828efd32cdd38a65df8d94d690720a63
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC FAM228A HMCN2

2.66e-041603539de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC CYP8B1 GRAP

2.76e-041623532ac02523348660e514d464f8f2434ee0c312d784
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL2 SPHK1 ZNF641

2.96e-04166353ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CHRDL1 FLNC GRAP

2.96e-04166353c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN1 HMCN2 STK38L

2.96e-041663538e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CRIM1 SPHK1 CYP8B1

3.01e-04167353d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC SPHK1 GRAP

3.17e-04170353dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC SPHK1 GRAP

3.17e-041703536035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC SPHK1 GRAP

3.17e-04170353c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 CHRDL1 GPR12

3.17e-04170353876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 CHRDL1 GPR12

3.17e-041703531f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CHRDL1 FLNC GRAP

3.28e-04172353c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCelldroplet-Marrow-nan-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDT1 SPHK1 GRAP

3.34e-0417335337825d0dda028cf677ff6ff16ea58bff75cb25a7
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

CRIM1 CYP8B1 GRAP

3.34e-04173353dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCelldroplet-Marrow-nan-24m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDT1 SPHK1 GRAP

3.34e-0417335335dc897e06f905419d44093a92170d2cec35dd51
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 FLNC CRIM1

3.34e-04173353901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 FLNC CRIM1

3.34e-04173353fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 FLNC KCTD11

3.34e-04173353ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 FLNC KCTD11

3.34e-04173353b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN1 KCTD11 GRAP

3.45e-041753533031f1eef3cfef8a7e5f57e567cb0868d06cac38
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC SPHK1 GRAP

3.51e-041763535d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL1 FLNC ANOS1

3.51e-04176353a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 CHRDL1 FLNC

3.57e-0417735388403b055eb9fdf96e4695fb6e0d78179e30a1e3
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPHK1 SEC14L5 GRAP

3.57e-04177353d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

ITGA8 CRIM1 SEC14L5

3.57e-041773537617270f49cd6b7ba66db72d20560cee985012b2
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

ITGA8 CRIM1 SEC14L5

3.57e-041773538220cc2fc0ee8764a67a3be51d75248be2453040
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA8 CHRDL1 CYP8B1

3.57e-04177353b75f519d72611b293d9684f7dcfb1b70fbf54a90
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 CHRDL1 FLNC

3.57e-041773538903aeaab61abd81a148ea623038c5114b8a183b
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA8 IRF1 ANOS1

3.63e-041783530fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

CHRDL1 CYP8B1 GRAP

3.69e-04179353411620201a860716a8773b92f50f7b94ef34a586
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL1 ANOS1 CYP8B1

3.69e-0417935340c65e8623547aeb80f9cd2366e29072467ce069
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

ITGA8 HMCN2 CRIM1

3.94e-04183353818fd886e0188091310825f9145fa53328f2c979
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IBA57 PODXL2 GPR12

3.94e-04183353262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IBA57 PODXL2 GPR12

3.94e-04183353c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC SPHK1 GRAP

3.94e-0418335338a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC SPHK1 CYP8B1

3.94e-04183353bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ITGA8 HMCN2 STK38L

3.94e-04183353cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1

4.00e-04184353968afa6b5ba84169377a24c150bb68749fa674d9
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA8 FLNC SPHK1

4.00e-04184353e33e2a887aafba7b6a31f00bb0dbe974b4359fd6
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

ITGA8 FLNC HMCN2

4.00e-041843530b336489c10e8c3c957795dd845454f03404382b
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1

4.00e-0418435315cbddea9efb2346a2028d77edfe9ba32923568f
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1

4.00e-041843530087c605c161fd8a39aa394f51994a04e8353bf1
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLNC SPHK1

4.00e-04184353920f95625978132c2b6c76654ef6298244103e2d
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC SPHK1 GRAP

4.00e-041843533b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC SPHK1 GRAP

4.00e-041843531a4297b9d3cc4744bea0408fd5ee7b33ba2a1d78
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL1 FLNC SPHK1

4.06e-041853539de1db2ce9e44956b1214daf6e1e161334679c88
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL1 FLNC SPHK1

4.06e-0418535318f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

PODXL2 LRFN1 TMEM132A

4.06e-041853539d53e0a92e4f99370be2e4be1dd737630796b1ca
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

FLNC SPHK1 GRAP

4.06e-0418535397a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL1 FLNC SPHK1

4.13e-0418635330dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CHRDL1 FLNC GRAP

4.13e-041863536b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL1 FLNC SPHK1

4.13e-04186353eeacf59a9e6bf1c9fd59b6b13d35e8abae228cf0
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

HMCN2 CRIM1 TMEM132A

4.13e-041863532e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

HMCN2 CRIM1 TMEM132A

4.13e-04186353c3449e54454009973818fc1101933c6f0168258c
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|343B / Donor, Lineage, Cell class and subclass (all cells)

FLNC SPHK1 GRAP

4.13e-041863537a8da2ad140bea3207bd868212cc5e201d586772
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|343B / Donor, Lineage, Cell class and subclass (all cells)

FLNC SPHK1 GRAP

4.13e-04186353dc394034929c6b10ae0e1c1a028cc3d4ce873298
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC CRIM1 GRAP

4.13e-0418635320340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

PODXL2 LRFN1 TMEM132A

4.19e-04187353fa0452f3382c22c0391b241d06504fda3c6a19f0
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

TRIOBP ZKSCAN5 LCMT2

4.19e-041873533c10b8501226c69d71bcd99dc1c064a3c2154f87
Drug(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A

ZNF10 IRF1 FLNC THRA ZKSCAN5

1.13e-051943553539_DN
DrugPimethixene maleate [13187-06-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A

ZNF10 IRF1 PODXL2 THRA RPAP2

1.18e-051963557426_UP
Drugfluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA

TRIOBP ZNF202 THEM6 CDT1 TMEM132A

1.21e-051973551075_DN
Diseaseneutrophil count

CHRDL1 IRF1 YY1AP1 THRA FAM228A STK38L ZKSCAN5 SPHK1 CYP8B1

1.47e-051382339EFO_0004833
Diseaseage of onset of asthma

IRF1 RPAP2

3.54e-0379332OBA_2001001
Diseaselymphocyte:monocyte ratio

CYP8B1 ACP2 RPAP2

4.04e-03288333EFO_0600088

Protein segments in the cluster

PeptideGeneStartEntry
EHFRPEKLREWPEPE

FAM228A

11

Q86W67
VEPEPELVVNPWDIV

GPR12

36

P47775
RGDIIEVLERPDPHW

GRAP

181

Q13588
VEPHPELRVWAVLPS

IBA57

151

Q5T440
WHPRFNVDEVPDIEP

CDT1

331

Q9H211
TLPDWHIPVEVVPDS

IRF1

191

P10914
LVEPPWHMPPREEEE

PODXL2

151

Q9NZ53
VTIVWDLPEEPDIPV

ANOS1

311

P23352
VDAWEVELRVLEPPH

HMCN2

1236

Q8NDA2
DPEPVVHWVAPDGRL

LRFN1

326

Q9P244
ARPTHWATEEPVVPV

FLNC

1761

Q14315
VHDCPSWDPERLEPV

LCA10

6

Q71F78
PQIVLPIHNWEPEEE

ITGA8

796

P53708
WQPIPVHTVPITEDR

ACP2

136

P11117
LETERPPQVEVHVWT

CHRDL1

366

Q9BU40
HRGEVDLEVPLWPTP

CRIM1

891

Q9NZV1
SHIPRWTPAPVREED

SEC14L5

176

O43304
PSLWELVEEHVPLRE

CCDC24

6

Q8N4L8
ALHWVEPREHIIPVV

CDH16

731

O75309
VDPDTPLPHVDPQRW

CYP8B1

466

Q9UNU6
PLITVLEHRPDCWPV

FOCAD

136

Q5VW36
HLEWAPRPVELPEVE

KCTD11

156

Q693B1
VDWEHIRERPAAIPI

STK38L

386

Q9Y2H1
RVEPPELPADLQHWI

THEM6

171

Q8WUY1
VTEPHQRPVPWDVRA

TMEM132A

111

Q24JP5
PEAWEEKPTHELPRE

TRIOBP

1491

Q9H2D6
IPKTPVWVREEERHP

RPAP2

151

Q8IXW5
WPEVVLPDPVEETRH

MRPL21

61

Q7Z2W9
EIQPHQWKPPIEREE

YY1AP1

356

Q9H869
EPWLVEREIHQETHP

ZNF10

71

P21506
LEEPVPSHWTVVPDE

SPHK1

241

Q9NYA1
QRPEPTPEEWDLIHI

THRA

156

P10827
WVRIPVEGEVPEARH

LCMT2

521

O60294
PVLGEPEIHQTPDWE

ZNF202

341

O95125
ILPEEFQPWVREHHP

ZKSCAN5

101

Q9Y2L8
QEERPWRTVPGPLEH

ZNF641

46

Q96N77