Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	apical plasma membrane	KCNA5 PRKAA1 NHS CYP4F2 PLEC TEK SLC4A2	8.70e-05	487	46	7	GO:0016324
GeneOntologyCellularComponent	apical part of cell	KCNA5 PRKAA1 NHS CYP4F2 PLEC TEK SLC4A2	2.89e-04	592	46	7	GO:0045177
Domain	RasGAP_dom	IQGAP3 PLXNB1 RASAL2	1.27e-05	18	48	3	IPR001936
Domain	Transcription_factor_COE	EBF2 EBF3	3.87e-05	4	48	2	IPR003523
Domain	COE_HLH	EBF2 EBF3	3.87e-05	4	48	2	IPR032201
Domain	COE_DBD	EBF2 EBF3	3.87e-05	4	48	2	IPR032200
Domain	Transcription_factor_COE_CS	EBF2 EBF3	3.87e-05	4	48	2	IPR018350
Domain	COE1_HLH	EBF2 EBF3	3.87e-05	4	48	2	PF16423
Domain	COE1_DBD	EBF2 EBF3	3.87e-05	4	48	2	PF16422
Domain	COE	EBF2 EBF3	3.87e-05	4	48	2	PS01345
Domain	cEGF	FBLN2 LRP4 LTBP3	3.97e-05	26	48	3	IPR026823
Domain	cEGF	FBLN2 LRP4 LTBP3	3.97e-05	26	48	3	PF12662
Domain	IPT	EBF2 EBF3 PLXNB1	4.46e-05	27	48	3	SM00429
Domain	Ig-like_fold	EBF2 SDK2 CD22 EBF3 MID1 OBSL1 TEK PLXNB1 SLC4A2	6.69e-05	706	48	9	IPR013783
Domain	TIG	EBF2 EBF3 PLXNB1	6.81e-05	31	48	3	PF01833
Domain	IPT	EBF2 EBF3 PLXNB1	7.50e-05	32	48	3	IPR002909
Domain	-	EBF2 SDK2 CD22 EBF3 MID1 OBSL1 TEK PLXNB1	2.60e-04	663	48	8	2.60.40.10
Domain	RasGAP	IQGAP3 RASAL2	5.77e-04	14	48	2	SM00323
Domain	RasGAP_CS	IQGAP3 RASAL2	5.77e-04	14	48	2	IPR023152
Domain	RasGAP	IQGAP3 RASAL2	6.65e-04	15	48	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	IQGAP3 RASAL2	6.65e-04	15	48	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	IQGAP3 RASAL2	6.65e-04	15	48	2	PS50018
Domain	Growth_fac_rcpt_	FBLN2 LRP4 LTBP3 TEK	6.85e-04	156	48	4	IPR009030
Domain	-	IQGAP3 RASAL2	7.58e-04	16	48	2	1.10.506.10
Domain	fn3	SDK2 MID1 OBSL1 TEK	7.88e-04	162	48	4	PF00041
Domain	FN3	SDK2 MID1 OBSL1 TEK	1.29e-03	185	48	4	SM00060
Domain	EGF_CA	FBLN2 LRP4 LTBP3	1.40e-03	86	48	3	PF07645
Domain	Rho_GTPase_activation_prot	IQGAP3 PLXNB1 RASAL2	1.50e-03	88	48	3	IPR008936
Domain	FN3	SDK2 MID1 OBSL1 TEK	1.69e-03	199	48	4	PS50853
Domain	EGF_Ca-bd_CS	FBLN2 LRP4 LTBP3	1.98e-03	97	48	3	IPR018097
Domain	FN3_dom	SDK2 MID1 OBSL1 TEK	2.02e-03	209	48	4	IPR003961
Domain	EGF_CA	FBLN2 LRP4 LTBP3	2.10e-03	99	48	3	PS01187
Domain	ASX_HYDROXYL	FBLN2 LRP4 LTBP3	2.16e-03	100	48	3	PS00010
Domain	Ig_E-set	EBF2 EBF3 PLXNB1	2.42e-03	104	48	3	IPR014756
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBLN2 LRP4 LTBP3	2.55e-03	106	48	3	IPR000152
Domain	EGF_3	FBLN2 LRP4 LTBP3 TEK	3.08e-03	235	48	4	PS50026
Domain	EGF	FBLN2 LRP4 LTBP3 TEK	3.08e-03	235	48	4	SM00181
Domain	EGF-like_dom	FBLN2 LRP4 LTBP3 TEK	3.79e-03	249	48	4	IPR000742
Domain	EGF_CA	FBLN2 LRP4 LTBP3	3.80e-03	122	48	3	SM00179
Domain	EGF-like_Ca-bd_dom	FBLN2 LRP4 LTBP3	3.97e-03	124	48	3	IPR001881
Domain	EGF_1	FBLN2 LRP4 LTBP3 TEK	4.12e-03	255	48	4	PS00022
Domain	EGF-like_CS	FBLN2 LRP4 LTBP3 TEK	4.48e-03	261	48	4	IPR013032
Domain	EGF_2	FBLN2 LRP4 LTBP3 TEK	4.72e-03	265	48	4	PS01186
Domain	Cyt_P450_E_grp-I	CYP2B6 CYP4F2	5.97e-03	45	48	2	IPR002401
Domain	Cyt_P450_CS	CYP2B6 CYP4F2	8.20e-03	53	48	2	IPR017972
Domain	CYTOCHROME_P450	CYP2B6 CYP4F2	9.43e-03	57	48	2	PS00086
Domain	-	CYP2B6 CYP4F2	9.76e-03	58	48	2	1.10.630.10
Domain	p450	CYP2B6 CYP4F2	9.76e-03	58	48	2	PF00067
Pubmed	Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.	EBF2 EBF3 ISL1	5.24e-08	6	49	3	9389446
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MID1 PRKAA1 SLTM OBSL1 IQGAP3 MFSD12 PLXNB1 RASAL2 SLC4A2	2.78e-07	650	49	9	38777146
Pubmed	Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b.	EBF2 EBF3 ISL1	4.30e-07	11	49	3	10704382
Pubmed	Transient and lineage-restricted requirement of Ebf3 for sternum ossification.	EBF2 EBF3 ISL1	5.73e-07	12	49	3	32398354
Pubmed	Control of the migratory pathway of facial branchiomotor neurones.	EBF2 EBF3 ISL1	7.44e-07	13	49	3	11076752
Pubmed	Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse.	EBF2 EBF3 ISL1	1.18e-06	15	49	3	25762221
Pubmed	Downregulation of Kv1.5 K channels by the AMP-activated protein kinase.	KCNA5 PRKAA1	1.94e-06	2	49	2	23221389
Pubmed	Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors.	EBF2 EBF3 ISL1	5.21e-06	24	49	3	20826655
Pubmed	The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.	EBF2 EBF3	5.83e-06	3	49	2	9151732
Pubmed	Multimodal Hox5 activity generates motor neuron diversity.	EBF2 EBF3 ISL1	9.36e-06	29	49	3	39289460
Pubmed	Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development.	EBF2 EBF3	1.16e-05	4	49	2	9151733
Pubmed	Cloning of a novel Olf-1/EBF-like gene, O/E-4, by degenerate oligo-based direct selection.	EBF2 EBF3	1.16e-05	4	49	2	12139918
Pubmed	Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11.	EBF2 EBF3	1.94e-05	5	49	2	12917357
Pubmed	Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction.	NCOR2 ISL1	1.94e-05	5	49	2	29033129
Pubmed	Expression patterns of the coe/ebf transcription factor genes during chicken and mouse limb development.	EBF2 EBF3	1.94e-05	5	49	2	15261831
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NCOR2 SLC38A10 LZTR1 LRP4 LTBP3 PLEC MED13L IQGAP3 MFSD12	2.09e-05	1105	49	9	35748872
Pubmed	Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.	EBF2 EBF3	4.07e-05	7	49	2	24786561
Pubmed	Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection.	EBF2 EBF3	5.42e-05	8	49	2	14993187
Pubmed	Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons.	ISL1 DAGLA	5.42e-05	8	49	2	23319656
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	SDK2 OBSL1 HEATR1 PLEC IQGAP3	6.66e-05	302	49	5	30561431
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	CD22 OBSL1 ISL1 TEK	8.16e-05	162	49	4	25826454
Pubmed	Filament-associated TSGA10 protein is expressed in professional antigen presenting cells and interacts with vimentin.	OBSL1 PLEC	8.69e-05	10	49	2	20797700
Pubmed	Regulation of axonal morphogenesis by the mitochondrial protein Efhd1.	PRKAA1 ISL1	8.69e-05	10	49	2	32414840
Pubmed	Sulfatase 1 promotes the motor neuron-to-oligodendrocyte fate switch by activating Shh signaling in Olig2 progenitors of the embryonic ventral spinal cord.	EBF2 ISL1	1.06e-04	11	49	2	23238718
Pubmed	An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development.	EBF2 EBF3	1.27e-04	12	49	2	30658714
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	CTBS LTBP3 MED13L	1.40e-04	71	49	3	33541421
Pubmed	Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.	MCMBP SLTM HEATR1	1.46e-04	72	49	3	33106477
Pubmed	Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.	EBF2 EBF3	1.50e-04	13	49	2	22421355
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	NCOR2 SLC38A10 FBLN2 FAM120C PRKAA1 LTBP3 PLEC BAG6 SLC4A2	1.70e-04	1451	49	9	30550785
Pubmed	Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk.	ISL1 TEK	2.02e-04	15	49	2	33510480
Pubmed	Spatiotemporal regulation of GLI target genes in the mammalian limb bud.	NCOR2 SDK2 EBF3 ISL1	2.09e-04	207	49	4	26238476
Pubmed	Control of neuronal morphology by the atypical cadherin Fat3.	EBF2 EBF3	2.30e-04	16	49	2	21903076
Pubmed	Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling.	KCNA5 EBF3	2.30e-04	16	49	2	17444492
Pubmed	Identification of transcripts with enriched expression in the developing and adult pancreas.	EBF2 LARGE2 SLC38A10 FBLN2 ISL1 MTCH1	2.36e-04	624	49	6	18554416
Pubmed	The Transcription Factors EBF1 and EBF2 Are Positive Regulators of Myelination in Schwann Cells.	EBF2 EBF3	2.61e-04	17	49	2	27889898
Pubmed	Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1.	EBF3 ISL1	2.61e-04	17	49	2	12023301
Pubmed	Megane/Heslike is required for normal GABAergic differentiation in the mouse superior colliculus.	EBF2 ISL1	3.27e-04	19	49	2	16968817
Pubmed	A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography.	EBF2 EBF3	3.64e-04	20	49	2	16774995
Pubmed	The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.	EBF2 EBF3	4.01e-04	21	49	2	27600842
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	MCMBP LZTR1 WDR97 PRKAA1 OBSL1 HEATR1 BAG6	4.07e-04	974	49	7	28675297
Pubmed	Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.	EBF2 EBF3	5.71e-04	25	49	2	15229182
Pubmed	Congenital Myasthenic Syndromes Overview	LRP4 PLEC	6.18e-04	26	49	2	20301347
Pubmed	miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors.	ISL1 TEK	6.18e-04	26	49	2	21708977
Pubmed	Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.	EBF2 EBF3	6.67e-04	27	49	2	33760820
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	MID1 OBSL1 APBA3 BAG6	6.82e-04	283	49	4	21903422
Pubmed	The DNA sequence and biology of human chromosome 19.	CYP2B6 CD22 APBA3 CYP4F2	6.91e-04	284	49	4	15057824
Pubmed	Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.	OBSL1 BAG6	7.18e-04	28	49	2	25752541
Pubmed	Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons.	EBF3 ISL1	7.18e-04	28	49	2	30796806
Pubmed	EBF2 determines and maintains brown adipocyte identity.	EBF2 EBF3	7.71e-04	29	49	2	23499423
Pubmed	SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron.	NCOR2 ISL1	7.71e-04	29	49	2	17928865
Pubmed	EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.	PLEC BAG6 PLXNB1	7.93e-04	128	49	3	23858473
Pubmed	Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.	EBF3 ISL1	8.25e-04	30	49	2	30127719
Pubmed	Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation.	ISL1 TEK	8.81e-04	31	49	2	15843414
Pubmed	c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections.	EBF2 ISL1	9.39e-04	32	49	2	22514301
Pubmed	Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons.	EBF2 ISL1	9.39e-04	32	49	2	36596814
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	LARGE2 NCOR2 LZTR1	1.07e-03	142	49	3	19851296
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	LARGE2 NCOR2 LZTR1	1.09e-03	143	49	3	20198315
Pubmed	Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.	ISL1 TEK	1.12e-03	35	49	2	28172500
Pubmed	OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin.	PRKAA1 TEK	1.12e-03	35	49	2	34157307
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NCOR2 EBF3 OBSL1 ISL1 HEATR1 WASF1	1.25e-03	857	49	6	25609649
Interaction	TANK interactions	SDK2 OBSL1 APBA3 HEATR1 PLEC IQGAP3	1.19e-05	216	48	6	int:TANK
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EBF2 FBLN2 OBSL1 LTBP3 GRIN3A	1.83e-06	185	49	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	Basal_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	LARGE2 SDK2 LRP4 NHS PLXNB1	2.14e-06	191	49	5	a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EBF2 EBF3 NHS ISL1 GRIN3A	2.20e-06	192	49	5	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 FBLN2 EBF3 MID1 MTCH1	2.62e-06	199	49	5	9846d6a31635fde759d55674631c11ab9270a603
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2B6 MID1 NHS PLXNB1	2.68e-05	157	49	4	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	10x5'-Liver-Hematopoietic_progenitors\|Liver / Manually curated celltypes from each tissue	MID1 NHS GRIN3A IQGAP3	3.33e-05	166	49	4	ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell	10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Liver / Manually curated celltypes from each tissue	MID1 NHS GRIN3A IQGAP3	3.33e-05	166	49	4	a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 FBLN2 EBF3 ISL1	4.27e-05	177	49	4	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EBF2 FBLN2 LTBP3 DAGLA	4.56e-05	180	49	4	39ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 FBLN2 EBF3 GRIN3A	5.40e-05	188	49	4	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	EBF2 FBLN2 EBF3 WASF1	5.63e-05	190	49	4	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	LARGE2 SDK2 MID1 NHS	5.86e-05	192	49	4	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	343B-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PSMF1 SCNN1D HEATR1 SLC4A2	5.86e-05	192	49	4	445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	LARGE2 SLC38A10 OBSL1 PLXNB1	6.47e-05	197	49	4	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EBF2 FBLN2 EBF3 OBSL1	6.47e-05	197	49	4	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LARGE2 SLC38A10 OBSL1 PLXNB1	6.47e-05	197	49	4	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	SDK2 LRP4 NHS PLXNB1	6.47e-05	197	49	4	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EBF2 FBLN2 EBF3 OBSL1	6.47e-05	197	49	4	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 FBLN2 EBF3 ISL1	6.47e-05	197	49	4	05e303fff86db31f7b742324c64980eb2b9cff9a
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EBF2 FBLN2 EBF3 OBSL1	6.47e-05	197	49	4	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	EBF2 FBLN2 KCNA5 EBF3	6.47e-05	197	49	4	9a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 FBLN2 EBF3 ISL1	6.60e-05	198	49	4	cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / Treatment groups by lineage, cell group, cell type	FBLN2 MID1 PLEC TEK	6.86e-05	200	49	4	b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	NCOR2 LZTR1 RASAL2 SLC4A2	6.86e-05	200	49	4	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 FBLN2 LRP4 WASF1	6.86e-05	200	49	4	8a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 FBLN2 LRP4 NHS	6.86e-05	200	49	4	4c3c11dd5e71ebc3d62264eeaeb71a850b149779
Computational	Genes upregulated in subsets of cells of a given type within various tumors	FBLN2 PLEC TEK	1.79e-04	50	24	3	GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_HEV_2
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	SLC38A10 LZTR1 OBSL1 WASF1 RASAL2 SLC4A2	3.54e-06	193	49	6	3262_UP
Disease	developmental disorder of mental health (implicated_via_orthology)	NCOR2 PLXNB1 RASAL2	7.06e-05	49	48	3	DOID:0060037 (implicated_via_orthology)
Disease	gliosarcoma	CYP2B6 LZTR1	3.06e-04	16	48	2	C0206726
Disease	obesity (implicated_via_orthology)	SDK2 PRKAA1 MED13L PLXNB1	4.15e-04	215	48	4	DOID:9970 (implicated_via_orthology)
Disease	Myasthenic Syndromes, Congenital	LRP4 PLEC	6.99e-04	24	48	2	C0751882
Disease	level of Phosphatidylethanolamine (18:0_18:2) in blood serum	SLTM DAGLA	9.53e-04	28	48	2	OBA_2045139
Disease	osteoarthritis (is_implicated_in)	NCOR2 BAG6	9.53e-04	28	48	2	DOID:8398 (is_implicated_in)
Disease	level of Phosphatidylcholine (18:0_20:4) in blood serum	ZBTB3 DAGLA	1.17e-03	31	48	2	OBA_2045094
Disease	diffuse plaque measurement	NCOR2 PSMF1 SDK2 FBLN2 SLC27A6 SLC4A2	1.38e-03	758	48	6	EFO_0010699

Protein segments in the cluster

Peptide	Gene	Start	Entry
AEHLPHRPAVEKDVP	nan	36	A8MUN3
RARPRAPHKPHEVFV	SLC4A2	311	P04920
VIGPHRPPELHDRAK	CYP2B6	331	P20813
VIHLVERAPPQTHLP	BAG6	81	P46379
RIQRHHTFLEPLPIP	ARMC2	851	Q8NEN0
PPVTTAIIHRPHARE	APBA3	481	O96018
ITPHAIRVQTPPRHI	EBF2	296	Q9HAK2
PELCRPIRHHPDFEV	CTBS	46	Q01459
TVHRVHVTFLPHEPP	LARGE2	411	Q8N3Y3
VQDPPVHIVDPREHV	OBSL1	801	O75147
HEIPREELRHTPELP	NCOR2	1426	Q9Y618
QHRPHSPRLVDIALP	FAM201A	136	Q5SY85
KRPLIPFHHRPSVAE	MED13L	481	Q71F56
PPLLHVAIREAEARP	LZTR1	506	Q8N653
PRKPQVLPHSHVEED	FBLN2	406	P98095
VEQPLPRHHALREAP	PLXNB1	1441	O43157
HPEPPETRASHLRVD	FAM47B	236	Q8NA70
RRHTVPDRHIPLALP	RASAL2	846	Q9UJF2
RILVHAPHPPLSVVR	IQGAP3	841	Q86VI3
LHIPVISIVRHEFPR	GRIN3A	216	Q8TCU5
RDERELLRHPPAPHQ	KCNA5	276	P22460
PPVAPEVLRVAEHRH	FAM120C	601	Q9NX05
LHPPVPVISRHVTQD	CYP4F2	391	P78329
PVVNVRVHHPPEASV	LTBP3	226	Q9NS15
PPGRIIHVVHNHPAE	DAGLA	601	Q9Y4D2
ALPHVPEHRRLPILV	HEATR1	1386	Q9H583
ITPHAIRVQTPPRHI	EBF3	306	Q9H4W6
VRQLPHAPEHPVATL	SDK2	586	Q58EX2
TVPRHEPPFHLDREI	SCNN1D	341	P51172
RHEPPVPHDKVVVDE	SLC38A10	496	Q9HBR0
ERRRPHAEEPGEHTP	MFSD12	241	Q6NUT3
RIHLNVSERPFPPHI	CD22	131	P20273
ATAREVDPLRIPPHH	PSMF1	161	Q92530
VHSPPASLVPRIHVI	MCMBP	296	Q9BTE3
VEARARDPPPAHRAH	MTCH1	36	Q9NZJ7
VHRHEPPVTAEPIRL	RPUSD2	211	Q8IZ73
PATRPPCVEELHRHA	NHS	216	Q6T4R5
VIIHDRPDITHPRHP	SLTM	856	Q9NWH9
PREFRLVEVHDPPLH	SUPT7L	26	O94864
EPISARQPALRPHVH	ISL1	161	P61371
HLTRPHPERVPFLVA	PRKAA1	366	Q13131
AHHDPPVAIRDPPVV	PRR19	41	A6NJB7
RLAVAPVPPHHVLRC	WDR97	251	A6NE52
VRHNSKEIPIEPAPH	MID1	586	O15344
PRHEVPDILEVHLPH	TEK	166	Q02763
IIDPVHSHRVPVDVA	PLEC	3611	Q15149
RPHEPEKVPRAPHDR	WASF1	186	Q92558
PDEPVPRSHHVVSLL	SLC27A6	201	Q9Y2P4
EVDAPHLRAPHPPVA	ZBTB3	251	Q9H5J0
DIHVFHRRRPPVSTP	LRP4	991	O75096