Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of synaptic transmission, glutamatergic	IQSEC2 GRIN2D CCKBR CACNG3 PTK2B	1.66e-05	43	154	5	GO:0051968
GeneOntologyCellularComponent	keratin filament	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	6.00e-07	97	154	8	GO:0045095
GeneOntologyCellularComponent	postsynaptic specialization	GPHN SEMA4F DLGAP1 IQSEC2 MPDZ GRIN2D EPB41L3 CACNG3 PRR12 PTK2B P2RX6 RNF10 BSN AKAP1	2.21e-05	503	154	14	GO:0099572
GeneOntologyCellularComponent	postsynaptic specialization, intracellular component	GPHN DLGAP1 IQSEC2 PTK2B AKAP1	5.74e-05	56	154	5	GO:0099091
GeneOntologyCellularComponent	postsynaptic density	GPHN SEMA4F DLGAP1 IQSEC2 MPDZ GRIN2D EPB41L3 CACNG3 PRR12 PTK2B RNF10 BSN	1.33e-04	451	154	12	GO:0014069
GeneOntologyCellularComponent	pericellular basket	SLC17A8 SLC17A6	1.61e-04	3	154	2	GO:1990030
GeneOntologyCellularComponent	asymmetric synapse	GPHN SEMA4F DLGAP1 IQSEC2 MPDZ GRIN2D EPB41L3 CACNG3 PRR12 PTK2B RNF10 BSN	2.23e-04	477	154	12	GO:0032279
GeneOntologyCellularComponent	intermediate filament	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	2.87e-04	227	154	8	GO:0005882
GeneOntologyCellularComponent	glutamatergic synapse	SEMA4F DLGAP1 IQSEC2 MPDZ CLASP2 GRIN2D CACNG3 PTK2B DIP2A P2RX6 EIF4EBP1 RNF10 SLC17A8 FGFR1 BSN EPHB1	3.58e-04	817	154	16	GO:0098978
GeneOntologyCellularComponent	neuron to neuron synapse	GPHN SEMA4F DLGAP1 IQSEC2 MPDZ GRIN2D EPB41L3 CACNG3 PRR12 PTK2B RNF10 BSN	5.10e-04	523	154	12	GO:0098984
GeneOntologyCellularComponent	postsynaptic specialization membrane	GPHN SEMA4F IQSEC2 GRIN2D CACNG3 P2RX6 RNF10	7.39e-04	201	154	7	GO:0099634
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	7.59e-04	263	154	8	GO:0045111
GeneOntologyCellularComponent	excitatory synapse	CACNG3 P2RX6 SLC17A8 BSN SLC17A6	1.18e-03	107	154	5	GO:0060076
GeneOntologyCellularComponent	postsynapse	GPHN SEMA4F DLGAP1 IQSEC2 MPDZ GRIN2D EPB41L3 CACNG3 PRR12 PTK2B DIP2A P2RX6 EIF4EBP1 RNF10 FGFR1 BSN AKAP1	1.39e-03	1018	154	17	GO:0098794
GeneOntologyCellularComponent	dendrite	GPHN SEMA4F FAT3 MPDZ TRAK1 CACNG3 PTK2B CNNM1 DIP2A P2RX6 SLC17A8 ELK1 BSN EPHA8 EPHB1	1.71e-03	858	154	15	GO:0030425
GeneOntologyCellularComponent	dendritic tree	GPHN SEMA4F FAT3 MPDZ TRAK1 CACNG3 PTK2B CNNM1 DIP2A P2RX6 SLC17A8 ELK1 BSN EPHA8 EPHB1	1.75e-03	860	154	15	GO:0097447
GeneOntologyCellularComponent	NMDA selective glutamate receptor complex	GRIN2D PTK2B	1.88e-03	9	154	2	GO:0017146
HumanPheno	Diagnostic behavioral phenotype	GPHN IQSEC2 HECTD4 POU4F1 GRIN2D AHDC1 JMJD1C SH2B1 TRAK1 KMT2C TRPM3 SETD5 PCDH15 USP7 FGFR1 SRRM2 RAI1 FBXW11	2.77e-05	747	45	18	HP:0025783
HumanPheno	Autistic behavior	GPHN IQSEC2 HECTD4 POU4F1 GRIN2D AHDC1 JMJD1C SH2B1 TRAK1 KMT2C TRPM3 SETD5 USP7 FGFR1 SRRM2 RAI1 FBXW11	3.08e-05	678	45	17	HP:0000729
Domain	KAP	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	1.86e-08	58	149	8	IPR002494
Domain	Keratin_B2_2	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	2.22e-08	39	149	7	PF13885
Domain	Keratin_B2	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-6 KRTAP10-12	7.15e-07	40	149	6	PF01500
Domain	PH_dom-like	ARHGAP23 IQSEC2 FRMPD1 TRIOBP TNS2 PLEKHG2 EPB41L3 PLEKHG5 SH2B1 PTK2B ARHGEF40 RALGPS1 MTMR3 GAB3 ADAP2	1.66e-06	426	149	15	IPR011993
Domain	-	ARHGAP23 IQSEC2 TRIOBP TNS2 PLEKHG2 EPB41L3 PLEKHG5 SH2B1 ARHGEF40 RALGPS1 MTMR3 GAB3 ADAP2	1.56e-05	391	149	13	2.30.29.30
Domain	PH	ARHGAP23 IQSEC2 TRIOBP PLEKHG2 PLEKHG5 SH2B1 ARHGEF40 RALGPS1 GAB3 ADAP2	8.06e-05	278	149	10	SM00233
Domain	PH_DOMAIN	ARHGAP23 IQSEC2 TRIOBP PLEKHG2 PLEKHG5 SH2B1 ARHGEF40 RALGPS1 GAB3 ADAP2	8.30e-05	279	149	10	PS50003
Domain	PH_domain	ARHGAP23 IQSEC2 TRIOBP PLEKHG2 PLEKHG5 SH2B1 ARHGEF40 RALGPS1 GAB3 ADAP2	8.55e-05	280	149	10	IPR001849
Pubmed	A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	2.10e-15	16	160	8	15028290
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA4F SPEG HECTD4 CLASP2 GRIN2D RALGAPA2 PLEKHG5 AHDC1 TRAK1 PRR12 KMT2C DIP2A ARHGEF40 PNPLA6 SETD5 CCDC34 RALGPS1 NISCH TMCC2 MTMR3 USP7 C19orf44 DIP2C FGFR1 PRRT4 RAI1 BAHCC1	1.36e-12	1105	160	27	35748872
Pubmed	Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6	3.91e-12	11	160	6	14962103
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SNPH SPEG FRMPD1 URB2 MAP3K4 TRAK1 GRAMD1B SETD5 NISCH SPHKAP MTMR3 YY1AP1 SRRM2 PLXNB3	7.09e-09	407	160	14	12693553
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	STIM2 ARHGAP23 EPB41L3 RALGAPA2 JMJD1C SH2B1 PRR12 CEP68 PARP4 LDB3 TRPM3 SPON1 TMCC2 DIP2C SLX4	1.04e-08	493	160	15	15368895
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BRPF3 NYAP2 CAND2 PHRF1 HECTD4 TRIOBP DIDO1 PLEKHG5 KIAA1614 KMT2C RALGPS1 MDC1 RNF10 BSN RAI1	2.63e-08	529	160	15	14621295
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	JCAD STIM2 NYAP2 ARHGAP23 PHRF1 KMT2C BAHCC1 EPHA8	2.76e-08	103	160	8	10819331
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BRPF3 IL16 ARHGAP23 FAT3 PHRF1 RPP38 ZNF318 EPB41L3 RALGAPA2 KIF20A ARHGEF40 PNPLA6 SETD5 INTS13 GLI3 RTL9 USP7 SRRM2 RAI1 BAHCC1	2.32e-07	1116	160	20	31753913
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	UIMC1 MRM1 PHRF1 RPP38 TRIOBP MPDZ DIDO1 CLASP2 ZNF318 URB2 AHDC1 GREB1L PRR12 KMT2C PIGT PNPLA6 SETD5 INTS13 MDC1 USP7 AKAP1 ARMC8 ZC3HAV1	4.09e-07	1497	160	23	31527615
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 GPHN DLGAP1 NYAP2 IQSEC2 HECTD4 TRIOBP MPDZ DIDO1 CLASP2 ZNF318 GRIN2D EPB41L3 NISCH SPHKAP BSN RAI1 ARMC8	5.34e-07	963	160	18	28671696
Pubmed	Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.	KRTAP10-1 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6	1.12e-06	40	160	5	12359730
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	UIMC1 SP1 TICRR PHRF1 RPP38 DIDO1 ZNF318 AHDC1 JMJD1C KIF20A PRR12 KMT2C LIN37 TINF2 INTS13 MDC1 USP7 SRRM2 RAI1 ZC3HAV1	2.29e-06	1294	160	20	30804502
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GPHN JCAD STIM2 IQSEC2 MPDZ CLASP2 PLEKHG2 EPB41L3 CBL TRAK1 PTK2B RNF10 RNF180 SRRM2 AKAP1 ZC3HAV1	2.56e-06	861	160	16	36931259
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	GPHN SPEG CLASP2 GRIN2D EPB41L3 PTK2B BSN SRRM2	1.26e-05	231	160	8	16452087
Pubmed	The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons.	POU4F1 BARHL1 SLC17A6	1.53e-05	11	160	3	21307253
Pubmed	EphB1 controls long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells.	POU4F1 SLC17A6 EPHB1	1.53e-05	11	160	3	38345254
Pubmed	Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family.	PEAK3 CBL PTK2B	2.04e-05	12	160	3	35192416
Pubmed	Genetic identification of spinal interneurons that coordinate left-right locomotor activity necessary for walking movements.	POU4F1 BARHL1 SLC17A6	2.04e-05	12	160	3	15134635
Pubmed	Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.	SIGLEC14 SIGLEC5	2.10e-05	2	160	2	24799499
Pubmed	Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog.	DIP2A DIP2C	2.10e-05	2	160	2	12137943
Pubmed	Identification of risk genes for autism spectrum disorder through copy number variation analysis in Austrian families.	GPHN DIP2A	2.10e-05	2	160	2	24643514
Pubmed	Stimulation of TRPM3 channels increases the transcriptional activation potential of Elk-1 involving cytosolic Ca2+, extracellular signal-regulated protein kinase, and calcineurin.	TRPM3 ELK1	2.10e-05	2	160	2	30552902
Pubmed	Sp1 is required for glucose-induced transcriptional regulation of mouse vesicular glutamate transporter 2 gene.	SP1 SLC17A6	2.10e-05	2	160	2	18440316
Pubmed	Deubiquitinase ZRANB1 drives hepatocellular carcinoma progression through SP1-LOXL2 axis.	SP1 ZRANB1	2.10e-05	2	160	2	34765294
Pubmed	Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway.	CBL EPHB1	2.10e-05	2	160	2	18034775
Pubmed	Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14.	SIGLEC14 SIGLEC5	2.10e-05	2	160	2	26459514
Pubmed	Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells.	SLC17A8 SLC17A6	2.10e-05	2	160	2	28559797
Pubmed	Elimination of inhibitory synapses is a major component of adult ocular dominance plasticity.	GPHN SLC17A6	2.10e-05	2	160	2	22542189
Pubmed	Sp1-mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in DNA damage response pathway.	SP1 MDC1	2.10e-05	2	160	2	18173747
Pubmed	Recruitment of proteins to DNA double-strand breaks: MDC1 directly recruits RAP80.	UIMC1 MDC1	2.10e-05	2	160	2	21857162
Pubmed	The DNA sequence of human chromosome 21.	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	2.78e-05	258	160	8	10830953
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JCAD DLGAP1 CRIM1 IQSEC2 HECTD4 TRIOBP CMYA5 SH2B1 DIP2A NISCH MTMR3 RNF10 USP7 YY1AP1 SLX4 PLXNB3 FBXW11 ARMC8	2.82e-05	1285	160	18	35914814
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPHN DLGAP1 PDE1C IL16 SNPH ARHGAP23 IQSEC2 CLASP2 EPB41L3 PLEKHG5 GRAMD1B PTK2B DIP2A PNPLA6 SPON1 NISCH USP7 BSN ARMC8	3.45e-05	1431	160	19	37142655
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TRERF1 AHDC1 JMJD1C PRR12 INTS13 MDC1 USP7 RAI1	3.64e-05	268	160	8	33640491
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SEMA4F TICRR IQSEC2 GARS1 IGDCC3 BCL3 KMT2C DIP2A PARP4 PRR35 TRPM3 PLXNB3 RAI1	3.91e-05	736	160	13	29676528
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	MKNK2 CBL MAP3K4 PTK2B GLI3 EIF4EBP1 ELK1 FGFR1 FBXW11	5.95e-05	371	160	9	25241761
Pubmed	Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.	SP1 USP7	6.29e-05	3	160	2	36759621
Pubmed	Genetic models of mammalian neural tube defects.	GLI3 GRHL3	6.29e-05	3	160	2	8005021
Pubmed	Median raphe controls acquisition of negative experience in the mouse.	SLC17A8 SLC17A6	6.29e-05	3	160	2	31780530
Pubmed	Transcriptional activation of TINF2, a gene encoding the telomere-associated protein TIN2, by Sp1 and NF-κB factors.	SP1 TINF2	6.29e-05	3	160	2	21731707
Pubmed	Homeostatic regulation of excitatory synapses on striatal medium spiny neurons expressing the D2 dopamine receptor.	SLC17A8 SLC17A6	6.29e-05	3	160	2	25782435
Pubmed	Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	11579105
Pubmed	Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	30577572
Pubmed	A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	32247614
Pubmed	Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing.	SP1 ELK1	6.29e-05	3	160	2	17804646
Pubmed	CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.	DIP2A DIP2C	6.29e-05	3	160	2	17236128
Pubmed	The kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1.	CBL EPHB1	6.29e-05	3	160	2	11713248
Pubmed	Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.	SLC17A8 SLC17A6	6.29e-05	3	160	2	33440152
Pubmed	SP1-activated USP27X-AS1 promotes hepatocellular carcinoma progression via USP7-mediated AKT stabilisation.	SP1 USP7	6.29e-05	3	160	2	38279869
Pubmed	SH2B1β interacts with STAT3 and enhances fibroblast growth factor 1-induced gene expression during neuronal differentiation.	SP1 SH2B1	6.29e-05	3	160	2	24396070
Pubmed	Docking and homology modeling explain inhibition of the human vesicular glutamate transporters.	SLC17A8 SLC17A6	6.29e-05	3	160	2	17660252
Pubmed	Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	25497369
Pubmed	Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	24698729
Pubmed	Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.	SLC17A8 SLC17A6	6.29e-05	3	160	2	23467360
Pubmed	Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	17012248
Pubmed	Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	31520477
Pubmed	Antiallergic effect of anti-Siglec-F through reduction of eosinophilic inflammation in murine allergic rhinitis.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	23710953
Pubmed	Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	19783675
Pubmed	FGF8-FGFR1 signaling acts as a niche factor for maintaining undifferentiated spermatogonia in the mouse.	NANOS3 FGFR1	6.29e-05	3	160	2	25359900
Pubmed	Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II.	MAP3K4 PTK2B	6.29e-05	3	160	2	15881658
Pubmed	Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	32134149
Pubmed	Siglec-F is a novel intestinal M cell marker.	SIGLEC14 SIGLEC5	6.29e-05	3	160	2	27524237
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 UIMC1 SP1 PHRF1 DIDO1 ZNF318 PNPLA6 MDC1 USP7 YY1AP1 SRRM2 AKAP1 ZC3HAV1	6.51e-05	774	160	13	15302935
Pubmed	Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling.	RPP38 DIDO1 USP7	7.41e-05	18	160	3	19640993
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TRIOBP CEP68 KMT2C SPON1 TMCC2 RNF10 DIP2C	8.72e-05	225	160	7	12168954
Pubmed	Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.	DIDO1 AHDC1 MAP3K4 KIF20A FGFR1 FBXW11 EPHA8	9.99e-05	230	160	7	29513927
Pubmed	Local protease signaling contributes to neural tube closure in the mouse embryo.	PRSS36 CFB GRHL3	1.03e-04	20	160	3	20152175
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	CAND2 HECTD4 CLASP2 LDB3 FBXW11	1.13e-04	102	160	5	9734811
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	BRPF3 RALGAPA2 GRAMD1B PRR12 PLXNB3	1.18e-04	103	160	5	10574462
Pubmed	Plexin-B2 controls the development of cerebellar granule cells.	SEMA4F BARHL1 SLC17A6	1.20e-04	21	160	3	17409257
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SNPH DIDO1 RALGPS1 MTMR3 SRRM2	1.23e-04	104	160	5	9205841
Pubmed	Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.	SIGLEC14 SIGLEC5	1.25e-04	4	160	2	17562860
Pubmed	Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils.	SIGLEC14 SIGLEC5	1.25e-04	4	160	2	17272508
Pubmed	Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility.	CBL PTK2B	1.25e-04	4	160	2	11149930
Pubmed	Exome analysis of Smith-Magenis-like syndrome cohort identifies de novo likely pathogenic variants.	IQSEC2 RAI1	1.25e-04	4	160	2	28213671
Pubmed	Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins.	PIGZ PIGT	1.25e-04	4	160	2	12655644
Pubmed	Ucma--A novel secreted factor represents a highly specific marker for distal chondrocytes.	GLI3 FGFR1	1.25e-04	4	160	2	17707622
Pubmed	Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.	SIGLEC14 SIGLEC5	1.25e-04	4	160	2	19178537
Pubmed	Src kinase activity is essential for osteoclast function.	CBL PTK2B	1.25e-04	4	160	2	14739300
Pubmed	A novel hematopoietic adaptor protein, Chat-H, positively regulates T cell receptor-mediated interleukin-2 production by Jurkat cells.	SH2D3C PTK2B	1.25e-04	4	160	2	12486027
Pubmed	Induction of Siglec-FhiCD101hi eosinophils in the lungs following murine hookworm Nippostrongylus brasiliensis infection.	SIGLEC14 SIGLEC5	1.25e-04	4	160	2	37251384
Pubmed	Phosphatase and tensin homolog regulates stability and activity of EphB1 receptor.	CBL EPHB1	1.25e-04	4	160	2	23118026
Pubmed	Barhl1 is required for maintenance of a large population of neurons in the zonal layer of the superior colliculus.	POU4F1 BARHL1	1.25e-04	4	160	2	16752387
Pubmed	4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass.	SH2B1 EIF4EBP1	1.25e-04	4	160	2	27217487
Pubmed	Glutamate inputs send prediction error of reward, but not negative value of aversive stimuli, to dopamine neurons.	SLC17A8 SLC17A6	1.25e-04	4	160	2	38278147
Pubmed	JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks.	JMJD1C MDC1	1.25e-04	4	160	2	24240613
Pubmed	Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.	SIGLEC14 SIGLEC5	1.25e-04	4	160	2	33289969
Pubmed	The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking.	CBL FGFR1	1.25e-04	4	160	2	20038681
Pubmed	IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils.	SIGLEC14 SIGLEC5	1.25e-04	4	160	2	33976385
Pubmed	Chromosomal localization of the gastric and brain receptors for cholecystokinin (CCKAR and CCKBR) in human and mouse.	BCL3 CCKBR	1.25e-04	4	160	2	7759110
Pubmed	Hair Cell Mechanotransduction Regulates Spontaneous Activity and Spiral Ganglion Subtype Specification in the Auditory System.	PCDH15 SLC17A8	1.25e-04	4	160	2	30078710
Pubmed	Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl.	CBL PTK2B	1.25e-04	4	160	2	25960397
Pubmed	USP7 controls NGN3 stability and pancreatic endocrine lineage development.	SPEG PNPLA6 USP7 NANOS3	1.51e-04	58	160	4	37117185
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	CCR10 SP1 DLGAP1 BRPF3 RPP38 GRIN2D EPB41L3 CCKBR	1.51e-04	329	160	8	17474147
Pubmed	Assessment of community efforts to advance network-based prediction of protein-protein interactions.	ZNF438 IL16 TMEM31 KRTAP10-1 KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-8 ZRANB1 PROP1	1.72e-04	630	160	11	36949045
Pubmed	Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs.	SIGLEC14 SIGLEC5	2.08e-04	5	160	2	20395633
Pubmed	Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13.	SIGLEC14 SIGLEC5	2.08e-04	5	160	2	21040544
Pubmed	Foxg1 regulates retinal axon pathfinding by repressing an ipsilateral program in nasal retina and by causing optic chiasm cells to exert a net axonal growth-promoting activity.	POU4F1 EPHB1	2.08e-04	5	160	2	19004857
Pubmed	Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells.	ELK1 EPHB1	2.08e-04	5	160	2	8798570
Pubmed	Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.	GLI3 USP7	2.08e-04	5	160	2	26120032
Interaction	NKD1 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8 ZRANB1	8.91e-09	21	154	6	int:NKD1
Interaction	ZNF625 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-8	6.89e-08	15	154	5	int:ZNF625
Interaction	ZNF264 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8 USP7	6.51e-07	41	154	6	int:ZNF264
Interaction	MOBP interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	7.35e-07	23	154	5	int:MOBP
Interaction	RSPO2 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-6	9.23e-07	24	154	5	int:RSPO2
Interaction	SPATA3 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	9.23e-07	24	154	5	int:SPATA3
Interaction	CLK4 interactions	KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8 SRRM2 ZRANB1	1.00e-06	44	154	6	int:CLK4
Interaction	WT1 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-8 ZRANB1	1.87e-06	76	154	7	int:WT1
Interaction	TOP3B interactions	SEMA4F SPEG HECTD4 CLASP2 GRIN2D RALGAPA2 PLEKHG5 AHDC1 TRAK1 PRR12 KMT2C DIP2A ARHGEF40 PNPLA6 SETD5 CCDC34 RALGPS1 NISCH TMCC2 MDC1 MTMR3 USP7 C19orf44 DIP2C FGFR1 PRRT4 RAI1 BAHCC1 ZC3HAV1	2.01e-06	1470	154	29	int:TOP3B
Interaction	LCE3E interactions	KRTAP10-1 GSC2 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	6.43e-06	60	154	6	int:LCE3E
Interaction	PIN1 interactions	GPHN SP1 TNS2 DIDO1 PLEKHG2 KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8 SRRM2 ZRANB1 RAI1	8.04e-06	383	154	13	int:PIN1
Interaction	ZNF587 interactions	TNS2 KRTAP10-1 GSC2 KRTAP10-9 KRTAP10-7 KRTAP10-8 TMCC2 ZRANB1	9.45e-06	135	154	8	int:ZNF587
Interaction	ZNF138 interactions	KRTAP10-1 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.16e-05	19	154	4	int:ZNF138
Interaction	BAHD1 interactions	SP1 TNS2 KRTAP10-1 KRTAP10-7 KRTAP10-8 ZRANB1	1.23e-05	67	154	6	int:BAHD1
Interaction	ZNF440 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.29e-05	40	154	5	int:ZNF440
Interaction	CSF1 interactions	CBL KRTAP10-8 USP7 GAB3	1.44e-05	20	154	4	int:CSF1
Interaction	TNKS interactions	UIMC1 MPDZ TNS2 KIF20A ARHGEF40 TINF2 MDC1	1.61e-05	105	154	7	int:TNKS
Interaction	ZNF581 interactions	IL16 KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8 TMCC2 ZRANB1	2.32e-05	111	154	7	int:ZNF581
Interaction	LCE3B interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	2.60e-05	46	154	5	int:LCE3B
Interaction	YWHAG interactions	GPHN JCAD TICRR DLGAP1 STIM2 ARHGAP23 SPEG IQSEC2 SH2D3C HECTD4 MPDZ TNS2 CLASP2 PLEKHG2 EPB41L3 CBL PLEKHG5 TRAK1 TINF2 MTMR3 SRRM2 ZRANB1 FBXW11 ZC3HAV1	2.64e-05	1248	154	24	int:YWHAG
Interaction	AVPI1 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	3.21e-05	48	154	5	int:AVPI1
Interaction	KRTAP4-4 interactions	TNS2 KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	3.65e-05	81	154	6	int:KRTAP4-4
Interaction	ZNF490 interactions	KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8 ZRANB1	3.92e-05	50	154	5	int:ZNF490
Interaction	SLC23A1 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8	4.30e-05	26	154	4	int:SLC23A1
Interaction	GID8 interactions	EPB41L3 PIGT SPON1 NISCH USP7 SLX4 ARMC8	4.49e-05	123	154	7	int:GID8
Interaction	ZNF439 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8	5.02e-05	27	154	4	int:ZNF439
Interaction	ZNF575 interactions	TNS2 KRTAP10-7 KRTAP10-8 ZRANB1	5.02e-05	27	154	4	int:ZNF575
Interaction	FAM74A4 interactions	KRTAP10-9 KRTAP10-7 KRTAP10-8 TMCC2	5.02e-05	27	154	4	int:FAM74A4
Interaction	ZNF433 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7	5.05e-05	10	154	3	int:ZNF433
Interaction	CCDC26 interactions	KRTAP10-9 KRTAP10-7 KRTAP10-8	5.05e-05	10	154	3	int:CCDC26
Interaction	HPCAL1 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8 C19orf44 TPSG1	5.84e-05	88	154	6	int:HPCAL1
Interaction	CRKL interactions	TNS2 PEAK3 CBL KIF20A USP7 FGFR1 ZRANB1 SLX4 EPHA8	6.41e-05	227	154	9	int:CRKL
Interaction	NUAK2 interactions	TRIOBP EPB41L3 USP7 SRRM2 FBXW11	6.81e-05	56	154	5	int:NUAK2
Interaction	ZNF155 interactions	KRTAP10-9 KRTAP10-7 KRTAP10-6	6.90e-05	11	154	3	int:ZNF155
Interaction	POM121L8P interactions	KRTAP10-1 KRTAP10-7 KRTAP10-8	6.90e-05	11	154	3	int:POM121L8P
Interaction	BRCC3 interactions	GPHN UIMC1 TNS2 CBL MDC1 USP7 ZRANB1	7.04e-05	132	154	7	int:BRCC3
Interaction	ZNF124 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8 ZRANB1	8.76e-05	59	154	5	int:ZNF124
Interaction	ZNF664 interactions	MPDZ KRTAP10-1 TRAK1 ZRANB1	8.79e-05	31	154	4	int:ZNF664
Interaction	ITIH4 interactions	DLGAP1 KIF20A P2RX6 ZRANB1	8.79e-05	31	154	4	int:ITIH4
Interaction	TNP2 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8	8.79e-05	31	154	4	int:TNP2
Interaction	BABAM2 interactions	UIMC1 TNS2 CBL MDC1 USP7 ZRANB1	8.96e-05	95	154	6	int:BABAM2
Interaction	GLIDR interactions	KRTAP10-9 KRTAP10-7 KRTAP10-8	9.15e-05	12	154	3	int:GLIDR
Interaction	PEAK3 interactions	PEAK3 CBL PTK2B	9.15e-05	12	154	3	int:PEAK3
Interaction	ZNF792 interactions	KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8 ZRANB1	9.50e-05	60	154	5	int:ZNF792
Interaction	YWHAH interactions	JCAD TICRR DLGAP1 STIM2 SPEG IQSEC2 HECTD4 MPDZ TNS2 CLASP2 PLEKHG2 EPB41L3 CBL PLEKHG5 TRAK1 MTMR3 RNF10 SRRM2 AKAP1 ZRANB1 ZC3HAV1	1.01e-04	1102	154	21	int:YWHAH
Interaction	ZNF572 interactions	IL16 KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8	1.03e-04	61	154	5	int:ZNF572
Interaction	KRTAP5-2 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.11e-04	62	154	5	int:KRTAP5-2
Interaction	FAM76B interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8 CCDC34 ZRANB1	1.13e-04	99	154	6	int:FAM76B
Interaction	BCL6B interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8	1.13e-04	33	154	4	int:BCL6B
Interaction	GSK3B interactions	SP1 TANK MKNK2 GARS1 TRIOBP MPDZ CLASP2 BCL3 EPB41L3 MAP3K4 TRAK1 EIF4EBP1 USP7 DMBT1 ZRANB1 SLX4 RAI1 FBXW11	1.17e-04	868	154	18	int:GSK3B
Interaction	WT1-AS interactions	KRTAP10-9 KRTAP10-8 TMCC2	1.18e-04	13	154	3	int:WT1-AS
Interaction	KRTAP12-1 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8 PRR35	1.20e-04	63	154	5	int:KRTAP12-1
Interaction	KRTAP5-4 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.20e-04	63	154	5	int:KRTAP5-4
Interaction	SLC6A20 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8	1.27e-04	34	154	4	int:SLC6A20
Interaction	AMMECR1 interactions	TNS2 KRTAP10-1 KRTAP10-8 USP7	1.27e-04	34	154	4	int:AMMECR1
Interaction	NPDC1 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.39e-04	65	154	5	int:NPDC1
Interaction	KRTAP5-11 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.50e-04	66	154	5	int:KRTAP5-11
Interaction	KRTAP5-3 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.50e-04	66	154	5	int:KRTAP5-3
Interaction	CRX interactions	TRERF1 SP1 TNS2 IRX6 PRR12 KMT2C PRR35 RAI1 BAHCC1	1.51e-04	254	154	9	int:CRX
Interaction	TLE5 interactions	ISX TNS2 IRX6 CBL KRTAP10-9 KRTAP10-7 KRTAP10-8 DIP2A PRR35 TMCC2 ZRANB1 PROP1	1.58e-04	443	154	12	int:TLE5
Interaction	LCE3C interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.61e-04	67	154	5	int:LCE3C
Interaction	LCE1E interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.73e-04	68	154	5	int:LCE1E
Interaction	LCE2A interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.85e-04	69	154	5	int:LCE2A
Interaction	OTX1 interactions	TNS2 KRTAP10-1 KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-8 ZRANB1	1.92e-04	155	154	7	int:OTX1
Interaction	PLEKHG5 interactions	MPDZ PLEKHG5 USP7 FBXW11	1.98e-04	38	154	4	int:PLEKHG5
Interaction	LCE1D interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	1.98e-04	70	154	5	int:LCE1D
Interaction	LRCH4 interactions	KRTAP10-7 KRTAP10-8 ZRANB1 FBXW11	2.19e-04	39	154	4	int:LRCH4
Interaction	ZNF32 interactions	KRTAP10-4 KRTAP10-7 KRTAP10-8	2.28e-04	16	154	3	int:ZNF32
Interaction	LCE3D interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	2.41e-04	73	154	5	int:LCE3D
Interaction	NAGK interactions	STIM2 TNS2 AHDC1 PIGT P2RX6 SETD5 RAI1	2.52e-04	162	154	7	int:NAGK
Interaction	LCE2D interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	2.57e-04	74	154	5	int:LCE2D
Interaction	YWHAB interactions	TICRR DLGAP1 STIM2 ARHGAP23 SPEG IQSEC2 HECTD4 TNS2 CLASP2 EPB41L3 CBL PLEKHG5 TRAK1 RALGPS1 MTMR3 FGFR1 SRRM2 ZRANB1 FBXW11	2.75e-04	1014	154	19	int:YWHAB
Interaction	ZNF578 interactions	KRTAP10-9 KRTAP10-7 KRTAP10-8	2.75e-04	17	154	3	int:ZNF578
Interaction	KRTAP4-5 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	2.91e-04	76	154	5	int:KRTAP4-5
Interaction	GRIA3 interactions	SEMA4F DLGAP1 HECTD4 USP7	3.21e-04	43	154	4	int:GRIA3
Interaction	ZNF837 interactions	TNS2 KRTAP10-9 KRTAP10-7 KRTAP10-8 ZRANB1	3.49e-04	79	154	5	int:ZNF837
Interaction	ZNF497 interactions	TNS2 KRTAP10-9 KRTAP10-8 ZRANB1	3.51e-04	44	154	4	int:ZNF497
Interaction	IQUB interactions	KRTAP10-9 KRTAP10-7 DIP2A TMCC2 ZRANB1	3.70e-04	80	154	5	int:IQUB
Interaction	LCE4A interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	3.70e-04	80	154	5	int:LCE4A
Interaction	LCE2B interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	3.92e-04	81	154	5	int:LCE2B
Interaction	HOXC8 interactions	TNS2 KRTAP10-9 KRTAP10-7 KRTAP10-8 USP7 ZRANB1	4.01e-04	125	154	6	int:HOXC8
Interaction	KIT interactions	SH2D3C MPDZ TNS2 CBL SH2B1 FGFR1	4.01e-04	125	154	6	int:KIT
Interaction	CATSPER1 interactions	TNS2 KRTAP10-1 KRTAP10-9 KRTAP10-4 KRTAP10-7 KRTAP10-8	4.19e-04	126	154	6	int:CATSPER1
Interaction	ZNF417 interactions	TNS2 KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-8 TMCC2 ZRANB1	4.45e-04	178	154	7	int:ZNF417
Interaction	GRB2 interactions	DLGAP1 TNS2 CLASP2 PEAK3 CBL SH2B1 PTK2B RALGPS1 NISCH RNF10 GAB3 ELK1 FGFR1 ZRANB1 EPHA8 EPHB1	4.59e-04	806	154	16	int:GRB2
Interaction	WDR26 interactions	EPB41L3 PIGT SPON1 MDC1 FGFR1 ZRANB1 ARMC8	4.60e-04	179	154	7	int:WDR26
Interaction	LCE1A interactions	KRTAP10-1 KRTAP10-9 KRTAP10-7 KRTAP10-6 KRTAP10-8	4.64e-04	84	154	5	int:LCE1A
Cytoband	21q22.3	ERVH48-1 KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8 DIP2A	3.17e-11	128	160	10	21q22.3
Cytoband	Ensembl 112 genes in cytogenetic band chr21q22	ERVH48-1 KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8 DIP2A	9.46e-07	377	160	10	chr21q22
GeneFamily	Keratin associated proteins	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	3.31e-07	109	110	8	619
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGAP23 TRIOBP PLEKHG2 PLEKHG5 SH2B1 RALGPS1 GAB3 ADAP2	3.76e-05	206	110	8	682
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	CMYA5 SPHKAP AKAP1	7.14e-04	29	110	3	396
GeneFamily	PHD finger proteins	BRPF3 PHRF1 DIDO1 KMT2C	2.22e-03	90	110	4	88
GeneFamily	PDZ domain containing	IL16 ARHGAP23 FRMPD1 MPDZ LDB3	2.37e-03	152	110	5	1220
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA8 EPHB1	3.18e-03	14	110	2	1095
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMPD1 EPB41L3 PTK2B	3.49e-03	50	110	3	1293
GeneFamily	Cadherin related	FAT3 PCDH15	4.70e-03	17	110	2	24
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP4 ZC3HAV1	4.70e-03	17	110	2	684
GeneFamily	Actins\|Deafness associated genes	TRIOBP PCDH15 CEACAM16 SLC17A8	5.02e-03	113	110	4	1152
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRTAP10-1 KRTAP10-9 KRTAP10-2 KRTAP10-4 KRTAP10-7 KRTAP10-6 KRTAP10-12 KRTAP10-8	5.96e-08	146	160	8	522c32103c24fc26836bb5b642083904682d9292
ToppCell	mild-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SNPH SH2B1 PARP4 ARHGEF40 FBXL18 RALGPS1 ELK1 PRR14L	6.63e-07	200	160	8	ca0a08bf162c954f037a56aa0cbb8b5d7c6ffec0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C FAT3 MUC5B LDB3 TRPM3 PCDH15 ADAMTS20	4.70e-06	184	160	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C FAT3 MUC5B LDB3 TRPM3 PCDH15 ADAMTS20	4.70e-06	184	160	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C FAT3 MUC5B LDB3 TRPM3 PCDH15 ADAMTS20	4.70e-06	184	160	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRERF1 CMYA5 PTK2B TRPM3 SPON1 SPHKAP SLC17A6	6.21e-06	192	160	7	25460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 CCKBR CACNG3 PTK2B SPHKAP BSN SLC17A6	6.43e-06	193	160	7	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 CCKBR CACNG3 PTK2B SPHKAP BSN SLC17A6	6.43e-06	193	160	7	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NYAP2 FAT3 CCKBR CACNG3 PTK2B BSN SLC17A6	6.87e-06	195	160	7	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	CAND2 ARHGAP23 PLEKHG5 KIAA1614 GLI3 TMCC2 FGFR1	6.87e-06	195	160	7	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRMPD1 IGDCC3 CMYA5 PRR35 TRPM3 P2RX6	9.47e-06	135	160	6	7b456fa9a5f5ce58976a8f1fad18c0f96a096930
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	JMJD1C GSC2 SETD5 PCDH15 ADAMTS20 GRHL3	1.66e-05	149	160	6	768877bade04ca0321593b8470b5011ad8270431
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCR10 INHBE SH2D3C GRAMD1B BSN	2.78e-05	98	160	5	a74fb790c135bd0d0033df3aca7b789d8b25e361
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCR10 INHBE SH2D3C GRAMD1B BSN	2.78e-05	98	160	5	cb0941481aef9068d7dbce0d1b6cf125f482a98d
ToppCell	343B-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	BRPF3 ARHGAP23 CADM4 FRMPD1 BAHCC1 EPHB1	4.10e-05	175	160	6	b30589ff9dc18e745afe61f289e6d576c9c6c6b2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE1C NYAP2 PARP4 TRPM3 SPHKAP EPHB1	4.80e-05	180	160	6	8923a42a6db9c6e9f3ce2ca9530e620dfea700ba
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDE1C SH2D3C PLEKHG2 BCL3 RALGAPA2 LINC01565	4.80e-05	180	160	6	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPHN EPB41L3 GRAMD1B TRPM3 PCDH15 SRRM2	5.26e-05	183	160	6	facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 CADM4 SIGLEC5 TRPM3 ADAMTS20 PLXNB3	5.43e-05	184	160	6	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F DLGAP1 CADM4 SIGLEC5 ADAMTS20 PLXNB3	5.43e-05	184	160	6	a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 AHI1-DT TRPM3 GLI3 DIP2C FGFR1	5.76e-05	186	160	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F DLGAP1 CADM4 SIGLEC5 ADAMTS20 PLXNB3	6.11e-05	188	160	6	8385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F DLGAP1 CADM4 SIGLEC5 ADAMTS20 PLXNB3	6.11e-05	188	160	6	921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell	facs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C CADM4 SPEG LDB3 ADAMTS20 PLXNB3	6.11e-05	188	160	6	794fc1d9a726945c42f7eac221eed938309b47a9
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F DLGAP1 CADM4 SIGLEC5 ADAMTS20 PLXNB3	6.11e-05	188	160	6	cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NYAP2 FRMPD1 GRIN2D GREB1L SPHKAP PCDH15	6.29e-05	189	160	6	f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	GPHN EPB41L3 JMJD1C GRAMD1B TRPM3 DIP2C	6.87e-05	192	160	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPHN AHI1-DT CMYA5 TRPM3 RALGPS1 DIP2C	7.07e-05	193	160	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	HECTD4 PTK2B TMCC2 MTMR3 RNF10 USP7	7.07e-05	193	160	6	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	IRX6 GSC2 BARHL1 SLC17A8	7.32e-05	62	160	4	3eec7f31de7cc24762c5b180475650676437dc76
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	IRX6 GSC2 BARHL1 SLC17A8	7.32e-05	62	160	4	f5f5441f5be00ab80a7827c4af1afbe45c552c2e
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	IRX6 GSC2 BARHL1 SLC17A8	7.32e-05	62	160	4	6e81a37b9defa96528654bee1b23152108d9c0b7
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	PDE1C CMYA5 GREB1L GRAMD1B LDB3 SPHKAP	7.48e-05	195	160	6	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	PDE1C CMYA5 GREB1L GRAMD1B LDB3 SPHKAP	7.48e-05	195	160	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	proximal-Hematologic-Interstitial_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF438 PEAK3 PRSS36 GRAMD1B PTGDR2 ADAP2	7.69e-05	196	160	6	b6a858c43fef42cd724d56c8283e954bcb546106
ToppCell	proximal-3-Hematologic-Interstitial_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF438 PEAK3 PRSS36 GRAMD1B PTGDR2 ADAP2	7.69e-05	196	160	6	d8c9cb86233470c3044865ad05ea202e294d80bf
ToppCell	proximal-Hematologic-Interstitial_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF438 PEAK3 PRSS36 GRAMD1B PTGDR2 ADAP2	7.69e-05	196	160	6	9d4d8ffe9d30de7d1dc33d261bc2aaf4189ad86c
ToppCell	5'-Adult-LymphNode-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD SH2D3C MPDZ TNS2 RALGAPA2 PCDH15	8.14e-05	198	160	6	d7e15e61b6018e4c36461c9471ee29601929925c
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP23 CADM4 EPB41L3 DIP2A PLXNB3 EPHB1	8.60e-05	200	160	6	0e85c90719d9ec51a566e230c9dd2909d8df1f52
ToppCell	Neuronal-Excitatory-eG(DAPK2)-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE1C NYAP2 PARP4 TRPM3 SPHKAP EPHB1	8.60e-05	200	160	6	7cea58e2691564e653cc972bf5aaff2df1f2666e
ToppCell	Neuronal-Excitatory-eG(DAPK2)--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE1C NYAP2 PARP4 TRPM3 SPHKAP EPHB1	8.60e-05	200	160	6	193c42c31a366a60d80c4c1fc6a1592a5b01a3ad
ToppCell	Neuronal-Excitatory-eG(DAPK2)---\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE1C NYAP2 PARP4 TRPM3 SPHKAP EPHB1	8.60e-05	200	160	6	7c780e995a5fc3793080da61b6bf7a12880e9df8
ToppCell	Neuronal-Excitatory-eG(DAPK2)----L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE1C NYAP2 PARP4 TRPM3 SPHKAP EPHB1	8.60e-05	200	160	6	d0b31dc5eedc0635c0d7ceabaa6202386cf2a4a4
ToppCell	Neuronal-Excitatory-eG(DAPK2)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE1C NYAP2 PARP4 TRPM3 SPHKAP EPHB1	8.60e-05	200	160	6	8444ae3c10b1152dec67ca812e6c417cc3b9cf89
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DLGAP1 GRIN2D SPON1 PCDH15 SLC17A8 ADAMTS20	8.60e-05	200	160	6	107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 CLASP2 DIP2A PIGT PLXNB3 FBXW11	8.60e-05	200	160	6	f0c338877e39226a90c4effe12f6501d33542a73
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP23 CADM4 EPB41L3 PIGZ DIP2A PLXNB3	8.60e-05	200	160	6	e5b4821fff40566c4a7dc3f74a14e27eb06b165d
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_3\|367C / Donor, Lineage, Cell class and subclass (all cells)	TICRR DDIAS TRPM3 PRRT4 EPHB1	1.11e-04	131	160	5	aeeb5718b3a7122492ad2659d5c8112f60839ff3
Drug	Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	POU4F1 MUC5B CCKBR LDB3 FBXL18 USP7 DMBT1 TPSG1 PTGDR2 SLC17A6	1.37e-06	198	159	10	2293_UP
Disease	thyroid nodule	EPB41L3 TRPM3	2.60e-05	2	151	2	EFO_1001436
Disease	Smith-Magenis syndrome	IQSEC2 RAI1	1.55e-04	4	151	2	C0795864
Disease	cortical thickness	ZNF438 SP1 NYAP2 CRIM1 FAT3 TRIOBP ZNF318 JMJD1C KIAA1614 ARHGEF40 SETD5 RALGPS1 GLI3 MTMR3 ADAMTS20 FGFR1	1.96e-04	1113	151	16	EFO_0004840
Disease	reticulocyte count	SP1 NYAP2 SOWAHD HECTD4 CBL JMJD1C GREB1L LINC01565 FBXL18 NISCH TMCC2 MTMR3 RNF10 BSN ZC3HAV1	3.18e-04	1045	151	15	EFO_0007986
Disease	electrocardiography	JCAD CAND2 CRIM1 SPEG JMJD1C TRAK1 LDB3 TRPM3 RNF10 FGFR1	4.21e-04	530	151	10	EFO_0004327
Disease	myeloid neoplasm (is_implicated_in)	CBL FGFR1	5.37e-04	7	151	2	DOID:0070004 (is_implicated_in)
Disease	mean corpuscular hemoglobin concentration	SP1 TICRR NYAP2 GARS1 HECTD4 SIGLEC5 ZNF318 URB2 SH2B1 LINC01565 PRR35 INTS13 TMCC2 MTMR3 ADAP2	5.68e-04	1105	151	15	EFO_0004528
Disease	breast cancer anti-estrogen resistance protein 3 measurement	SH2D3C JMJD1C	7.14e-04	8	151	2	EFO_0008040
Disease	Growth Disorders	CBL TINF2 RAI1	8.29e-04	36	151	3	C0018273
Disease	testosterone measurement	ZNF438 DLGAP1 NYAP2 IQSEC2 ZNF318 JMJD1C SH2B1 GRAMD1B CEP68 ARHGEF40 NISCH RTL9 USP7 YY1AP1 FGFR1 RAI1	8.62e-04	1275	151	16	EFO_0004908
Disease	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement	SIGLEC14 SIGLEC5	1.14e-03	10	151	2	EFO_0801544
Disease	Malignant neoplasm of breast	TRERF1 ZNF438 INHBE TANK FRMPD1 ZNF318 GRIN2D EPB41L3 KRTAP10-8 NISCH MTMR3 DIP2C FGFR1 SLC17A6	1.28e-03	1074	151	14	C0006142
Disease	Neurodevelopmental Disorders	DLGAP1 IQSEC2 KMT2C SETD5	1.35e-03	93	151	4	C1535926
Disease	age-related hearing impairment	NYAP2 TRIOBP ZNF318 GLI3 PRR14L RNF180 ZRANB1	1.45e-03	324	151	7	EFO_0005782
Disease	response to beta blocker	PNPLA6 CCDC34 SPHKAP	1.59e-03	45	151	3	EFO_0007766
Disease	Gastric Adenocarcinoma	SPEG EPHA8 EPHB1	1.59e-03	45	151	3	C0278701
Disease	sialic acid-binding Ig-like lectin 14 measurement	SIGLEC14 SIGLEC5	1.66e-03	12	151	2	EFO_0008284
Disease	microphthalmia (implicated_via_orthology)	CRIM1 TRPM3	1.66e-03	12	151	2	DOID:10629 (implicated_via_orthology)
Disease	melanoma	ZNF438 RPP38 PTK2B CNNM1 ADAMTS20 RAI1	1.79e-03	248	151	6	C0025202
Disease	platelet component distribution width	JCAD NYAP2 TANK SIGLEC14 SIGLEC5 JMJD1C CEP68 TRPM3 TMCC2 USP7 NANOS3	1.81e-03	755	151	11	EFO_0007984
Disease	high density lipoprotein particle size measurement	INHBE NYAP2 PIGT NISCH RAI1	1.86e-03	170	151	5	EFO_0008592
Disease	Leukemia, Myelocytic, Acute	POU4F1 CBL KMT2C EIF4EBP1 SLX4	2.01e-03	173	151	5	C0023467
Disease	response to fenofibrate	JMJD1C GLI3 SPON1	2.16e-03	50	151	3	GO_1901557
Disease	cholesteryl esters to total lipids in IDL percentage	NYAP2 BCL3 JMJD1C	2.16e-03	50	151	3	EFO_0022247
Disease	mean reticulocyte volume	SP1 DLGAP1 NYAP2 CRIM1 ZNF318 URB2 JMJD1C SH2B1 DIP2A TMCC2 ADAP2	2.80e-03	799	151	11	EFO_0010701
Disease	pancreatitis	JCAD HECTD4	2.98e-03	16	151	2	EFO_0000278
Disease	reticulocyte measurement	GPHN SP1 NYAP2 SOWAHD HECTD4 CBL JMJD1C LINC01565 NISCH TMCC2 MTMR3 BSN ZC3HAV1	3.04e-03	1053	151	13	EFO_0010700
Disease	intelligence, self reported educational attainment	PDE1C TANK JMJD1C BSN	3.12e-03	117	151	4	EFO_0004337, EFO_0004784
Disease	Polydactyly	PNPLA6 GLI3 FGFR1 ARMC8	3.12e-03	117	151	4	C0152427
Disease	von Willebrand factor measurement, coronary artery disease	JCAD HECTD4 BARHL1 NANOS3	3.22e-03	118	151	4	EFO_0001645, EFO_0004629
Disease	IGA glomerulonephritis	NYAP2 SPHKAP MTMR3	3.30e-03	58	151	3	EFO_0004194
Disease	immature platelet measurement	JCAD JMJD1C TRPM3 TMCC2	3.32e-03	119	151	4	EFO_0803541
Disease	lean body mass	SNPH NYAP2 DIDO1 ARHGEF40 GLI3 MTMR3 NANOS3	3.47e-03	379	151	7	EFO_0004995
Disease	lymphocyte count	JCAD INHBE IL16 NYAP2 HECTD4 SIGLEC5 CBL JMJD1C GRAMD1B DIP2A FBXL18 USP7 C19orf44 DMBT1 RAI1 ZC3HAV1	3.48e-03	1464	151	16	EFO_0004587
Disease	velopharyngeal dysfunction	MPDZ DIP2A INTS13 PCDH15	3.63e-03	122	151	4	EFO_0009336
Disease	sinusitis (is_marker_for)	MUC5B CFB	3.77e-03	18	151	2	DOID:0050127 (is_marker_for)
Disease	peripheral neuropathy, response to docetaxel trihydrate	NYAP2 SPHKAP	4.20e-03	19	151	2	EFO_0003100, GO_1902519
Disease	mean arterial pressure	STIM2 NYAP2 HECTD4 TNS2 ZNF318 USP7 NANOS3 BAHCC1	4.29e-03	499	151	8	EFO_0006340
Disease	neutrophil count, eosinophil count	SP1 ARHGAP23 HECTD4 JMJD1C LINC01565	4.89e-03	213	151	5	EFO_0004833, EFO_0004842
Disease	Calcium channel blocker use measurement	STIM2 NYAP2 ZNF318 AHDC1 NANOS3	4.89e-03	213	151	5	EFO_0009930

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDSSTPLPIVRRTQC	URB2	556	Q14146
TEPSPALLVSSSCRR	BAHCC1	2041	Q9P281
PCRRSESSGILPNTT	AKAP1	101	Q92667
PRRPRLSSCSAPTET	CCR10	341	P46092
SRSTSPSPLEACLEA	ELK1	196	P19419
DRPTGRLSTCLLSAP	ARHGEF40	156	Q8TER5
FPQTLSLPRTTTICS	CEP68	131	Q76N32
RDTLRLMCSSPSPTA	CEACAM16	146	Q2WEN9
RCSELVSSTSLPRLS	LINC01565	11	O15544
ARCEQPTSPRSLTLT	A2ML1	1336	A8K2U0
SCSQTPSRAIPATRR	EIF4EBP1	6	Q13541
DCRSPLELSPRSESS	BARHL1	31	Q9BZE3
SSRSTEPRSRDLSPI	CACNG3	236	O60359
PRSRSCSESEGERSP	BRPF3	976	Q9ULD4
DECVSLRSSSPPRTT	DLGAP1	506	O14490
SAPPADVSACLRRRS	AHI1-DT	111	P0C7V0
PTPLRCDSRASTVSP	AHDC1	1051	Q5TGY3
SSSVGNLSCEPPRIR	CCKBR	31	P32239
STPACSPILRKRSRS	GRAMD1B	16	Q3KR37
SRPSDRQSCVLTPCS	ADAMTS20	1121	P59510
TIVTPERRFVLTCPS	ADAP2	331	Q9NPF8
TSTALRRLAPPTSCC	ISX	171	Q2M1V0
STTSPALPVSTVCVR	MUC5B	1321	Q9HC84
RSLESSPAPERLCSF	NANOS3	46	P60323
CTRSLTALSEPRTPG	RAI1	1056	Q7Z5J4
SARFSRRPTCPDTSV	RALGPS1	311	Q5JS13
PASARRLSVPRDSAC	IRX6	386	P78412
PRAQATSRLSTASCP	GPHN	271	Q9NQX3
RISPVDVNSRPSSCL	INTS13	336	Q9NVM9
EGTTRALRLPPTTTC	CFB	601	P00751
SRSPAEASPICTCRT	EPHB1	291	P54762
HSSSEAIRRACLPTP	POU4F1	26	Q01851
SLETPSAPLLSRCVS	PNPLA6	406	Q8IY17
PGRVSRSTSDPTLCT	FAM189A1	391	O60320
LALPRVPRFSSLSSC	GLI3	1016	P10071
TTANRPSPVRDLCSS	KMT2C	1941	Q8NEZ4
SLRGASERTALSPPC	IGDCC3	611	Q8IVU1
SPSVRERECSPSSPL	LIN37	126	Q96GY3
QLVTPEPTSRATRCR	MDC1	1586	Q14676
RRSSTPIEHAPVCTS	LDB3	296	O75112
RTVPCSRTSFLSPER	GAB3	471	Q8WWW8
SSRDSLREPPATGLC	IQSEC2	716	Q5JU85
SLPRVLSPESLSCTE	JCAD	231	Q9P266
LSRCSFHPIPTRSST	JMJD1C	681	Q15652
PSRSAVLRTCELPPS	KIAA1614	846	Q5VZ46
SLCRISSVPGTSRVE	BSN	1641	Q9UPA5
STSCCVPTARRPLSL	INHBE	311	P58166
RTSARIVCVTSPAPN	PLXNB3	886	Q9ULL4
LVRATSRCLQLSPPS	MKNK2	426	Q9HBH9
APSTSSTCRLTLPVI	PDE1C	641	Q14123
PSKACRLRTPGSLST	PEAK3	36	Q6ZS72
CPPSLLRLEETASSS	DDIAS	391	Q8IXT1
PRAPASTLCLRTLVE	FBXW11	476	Q9UKB1
TLTVRTRLTAPPSLC	IL16	296	Q14005
SRPRGRECSPTSSLE	PHRF1	1116	Q9P1Y6
STSSPQLRLPHTLRC	KLK11	181	Q9UBX7
TPVVTSRLGRCSVSP	NYAP2	586	Q9P242
SALPEALCSQSRTTP	PARP4	1481	Q9UKK3
DTLTIPLSRLCVPRS	HECTD4	1791	Q9Y4D8
VLRSSSTSDIPEPLC	RALGAPA2	761	Q2PPJ7
SIEASLRCSSVVPRP	GREB1L	21	Q9C091
STARSASPLALCSRP	PTGDR2	346	Q9Y5Y4
LPKASPSLTRFCSRS	PRR35	346	P0CG20
LRTPVNLSAASRPVC	PRSS36	416	Q5K4E3
SPSRPCVLHSSLSRR	PCDH15	1701	Q96QU1
LRCLRTIFTSPVTPE	ARMC8	126	Q8IUR7
SSSNRLPLKRTCSPF	GRHL3	481	Q8TE85
LSSLPERSLPARAAC	GSC2	26	O15499
DCRPRSRPSSDSCSV	CCDC34	21	Q96HJ3
PLSCSNSTRSLLSPL	CCDC34	56	Q96HJ3
AVLVTATLCTARPSP	FGFR1	11	P11362
LASCRPPTTASRIRA	C19orf44	76	Q9H6X5
RPARAHSCTTAPLSR	FRMPD1	1381	Q5SYB0
CSLPSERAIFRTAPS	CMYA5	3791	Q8N3K9
SLRATATVSRCPPPA	EPHA8	901	P29322
SLASTLSPDCRRRPQ	FAT3	4441	Q8TDW7
VELSCLVPRSRPAAT	CADM4	141	Q8NFZ8
SESCPSVSCERPVLR	CRIM1	786	Q9NZV1
CASSPEALTVAIRRP	DIP2C	651	Q9Y2E4
RDPRTAPSSSCTAVA	DIDO1	966	Q9BTC0
PCLTLVCTPVSRVSS	KRTAP10-1	41	P60331
RPSSSVSLLCRPVCS	KRTAP10-2	226	P60368
PCLSLVCTPVSRVSS	KRTAP10-4	51	P60372
PCLSLVCTPVSRVSS	KRTAP10-6	51	P60371
SSSVSLLCRPVCRPA	KRTAP10-7	306	P60409
SSSVSLLCRPVCRPA	KRTAP10-8	206	P60410
PCLTLVCTPVSRVSS	KRTAP10-9	41	P60411
PCLSLVCTPVSRVSS	KRTAP10-12	46	P60413
RPLRPLDTSQSSRAC	CBL	706	P22681
CASSPEALTVAIRRP	DIP2A	666	Q14689
PSDRPRFTELVCSLS	PTK2B	666	Q14289
RSPTCLRALLDSAAP	BCL3	216	P20749
RVPTSPTAIRTLIQC	CAND2	226	O75155
CSAAQSRSTPRPDTL	DMBT1	701	Q9UGM3
PLPSATQRRASCSPL	FAM86C2P	121	A6NEL3
PSVSGPRRLVSCLSS	SPACA3	21	Q8IXA5
PSTHCAPTSPTELRR	EPB41L3	516	Q9Y2J2
STLSLTRSPCALPLA	MTMR3	906	Q13615
AISDCRPSRPSHTLS	POM121L1P	251	Q3SYA9
ECLRRSSAPAPTATA	P2RX6	401	O15547
SLCTLSAPTRLEPET	PRR14L	1566	Q5THK1
IPDCRPSRPSHTLSS	nan	211	A6NNC1
AISDCRPSRPSHTLS	nan	481	A6NNC1
DCRPSRPSHTLSSLA	nan	756	A6NNC1
SSTPCPLCRTIISRV	RNF180	466	Q86T96
IARPARQTSRTDCPA	MAP3K4	206	Q9Y6R4
STPLRRPSACETVST	RTL9	911	Q8NET4
RPRLSIPCSSITDVR	SH2B1	316	Q9NRF2
DSRSPCSRLTVNVPI	SPHKAP	1241	Q2M3C7
SNCPVAVTESTPRRR	SPON1	126	Q9HCB6
TLSSRILPVCLPEAS	TPSG1	136	Q9NRR2
TPRRSRSVSPCSNVE	SRRM2	946	Q9UQ35
RSVSPCSNVESRLLP	SRRM2	951	Q9UQ35
RTPSRGRSECDSSPE	SRRM2	1471	Q9UQ35
SLSRSVPACQVPRLS	RPP38	151	P78345
PRTSLPISEADSCLT	SEMA4F	41	O95754
CRPRSSSTTDTALLL	TMCC2	216	O75069
TSRRNSCPLTPVVSK	MRM1	176	Q6IN84
RSLSLPVCSVADSAP	FBXL18	416	Q96ME1
LLRRSLSAASCPPIS	GARS1	31	P41250
CPLRITTDPTVLATT	SETD5	721	Q9C0A6
PVTSLTTASRCNTPL	SETD5	891	Q9C0A6
LEPLESGRPTRLSCS	SIGLEC5	151	O15389
APSITSVTPRGLCRD	TANK	206	Q92844
APTASLAPTSQSLRC	SOWAHD	11	A6NJG2
LPDLVSSCRSRPALS	PRR12	1121	Q9ULL5
SIRRISCRSLSQPSP	SNPH	471	O15079
SQPSPLALLAATCSR	SP1	56	P08047
CALRDNPRASSPSRT	TRIOBP	676	Q9H2D6
LVPATPLASRSRDCS	SLX4	1256	Q8IY92
IPRSQGCSREASPSR	CLASP2	496	O75122
PCSRSDGLRSPSEVV	CNNM1	841	Q9NRU3
STPVATPCTPRRLSL	TRAK1	706	Q9UPV9
TPCTPRRLSLAESFT	TRAK1	711	Q9UPV9
RCRLPSRRTPTTSSD	TMEM31	51	Q5JXX7
APPLERSRLATTSFC	SLC17A6	206	Q9P2U8
SVLARNVSTRSCPPR	PLEKHG5	16	O94827
SAPSRSLSELCLAVP	PLEKHG5	896	O94827
SSTAQPRRECLTPIR	TICRR	1231	Q7Z2Z1
CRRTVPPTTQSELDS	MPDZ	631	O75970
RTLTEPCPLASESRV	PIGT	266	Q969N2
TCSARLTVRPSLAPL	SPEG	1051	Q15772
SLCRSRRSIVPSSPQ	STIM2	511	Q9P246
RNLLPRTPTCQSSTD	KIF20A	851	O95235
AIPVSSCDCRDSSRP	TINF2	436	Q9BSI4
TLAIVPDSRRPSSCI	TRPM3	1411	Q9HCF6
ASQRSSARTPACPTR	ARHGAP23	381	Q9P227
TTEVCSLDTPSRPLA	RNF10	431	Q8N5U6
DSRLSAAPCIRPSSS	NISCH	476	Q9Y2I1
VPLSTVLLDPTRSCT	NISCH	946	Q9Y2I1
RDSSSMLLCSSPDRP	PRRT4	811	C9JH25
SVAVLLSTAAPPSCR	ERVH48-1	31	M5A8F1
PSSSCRSVLFPLLIS	PIGZ	86	Q86VD9
TPTTTVDSSAPPCRR	PROP1	31	O75360
KRRSLAATPSSSLPC	YY1AP1	36	Q9H869
VTRSDGCPTSTSLPR	SH2D3C	371	Q8N5H7
TSLPRPRDSIRSCAL	SH2D3C	381	Q8N5H7
SRCEIPEGSRLPSLS	PLEKHG2	646	Q9H7P9
CDSFPIRRLSTPSSV	ZC3HAV1	581	Q7Z2W4
LVATRTCTVTPEAPR	VSIG10L	566	Q86VR7
ERFSRLSESVLSPPC	USP7	76	Q93009
LTSRMLPCHSPSRSD	ZNF438	46	Q7Z4V0
TTRVSPAHRSPTVLC	ZNF318	2026	Q5VUA4
CRPSDASATRSRPLA	UIMC1	121	Q96RL1
LEPLESGRPTRLSCS	SIGLEC14	151	Q08ET2
ARASSAALSCSPRPT	TNS2	1296	Q63HR2
PCRPRTLLSATNDAS	WDR73	351	Q6P4I2
QCLSQRRTRSPTESP	ZRANB1	106	Q9UGI0
APPLERSRLATTSFC	SLC17A8	211	Q8NDX2
TPTPRVLLCRSNSID	TRERF1	746	Q96PN7
AESCLPSTRRRPSLS	FAM53A	211	Q6NSI3
APTSRSLEDLSSCPR	GRIN2D	1266	O15399