Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin binding	MYO5A MAP2 MYO5B SCNN1A DAAM2 ACTN3 WDR1 EPB41L3 ACE MYO5C	3.24e-05	479	84	10	GO:0003779
GeneOntologyMolecularFunction	calcium ion sensor activity	EFHB MICU1	3.62e-04	7	84	2	GO:0061891
GeneOntologyMolecularFunction	calmodulin binding	MYO5A MAP2 MYO5B OBSCN ACE MYO5C	4.21e-04	230	84	6	GO:0005516
GeneOntologyMolecularFunction	metal ion sensor activity	EFHB MICU1	4.82e-04	8	84	2	GO:0140784
GeneOntologyMolecularFunction	microfilament motor activity	MYO5A MYO5B MYO5C	5.45e-04	38	84	3	GO:0000146
GeneOntologyMolecularFunction	cytoskeletal protein binding	MYO5A MAP2 MYO5B KIF1B OBSCN SCNN1A DAAM2 ACTN3 WDR1 EPB41L3 ADNP ACE MYO5C	6.49e-04	1099	84	13	GO:0008092
GeneOntologyBiologicalProcess	vesicle transport along actin filament	MYO5A MYO5B MYO5C	5.57e-06	9	85	3	GO:0030050
GeneOntologyBiologicalProcess	vesicle cytoskeletal trafficking	MYO5A MAP2 MYO5B KIF1B MYO5C	8.34e-06	67	85	5	GO:0099518
GeneOntologyBiologicalProcess	actin filament-based transport	MYO5A MYO5B MYO5C	1.09e-05	11	85	3	GO:0099515
GeneOntologyBiologicalProcess	secretory granule localization	MYO5A MAP2 KIF1B MYO5C	1.13e-05	34	85	4	GO:0032252
GeneOntologyBiologicalProcess	cellular response to mineralocorticoid stimulus	FOXO3 SCNN1A ACE	2.38e-05	14	85	3	GO:0071389
GeneOntologyBiologicalProcess	positive regulation of intestinal cholesterol absorption	ENPP7 ACAT2	1.00e-04	4	85	2	GO:0045797
GeneOntologyBiologicalProcess	positive regulation of intestinal lipid absorption	ENPP7 ACAT2	1.66e-04	5	85	2	GO:1904731
GeneOntologyBiologicalProcess	positive regulation of intestinal absorption	ENPP7 ACAT2	1.66e-04	5	85	2	GO:1904480
Domain	Myosin_S1_N	MYO5A MYO5B MYO5C	8.41e-07	5	83	3	IPR008989
Domain	DIL	MYO5A MYO5B MYO5C	1.68e-06	6	83	3	PF01843
Domain	Dilute_dom	MYO5A MYO5B MYO5C	1.68e-06	6	83	3	IPR002710
Domain	DILUTE	MYO5A MYO5B MYO5C	1.68e-06	6	83	3	PS51126
Domain	DIL	MYO5A MYO5B MYO5C	1.68e-06	6	83	3	SM01132
Domain	POLO_box_2	PLK2 PLK3	5.84e-05	3	83	2	IPR033695
Domain	-	PLK2 PLK3	1.16e-04	4	83	2	3.30.1120.30
Domain	POLO_box	PLK2 PLK3	1.16e-04	4	83	2	PF00659
Domain	POLO_BOX	PLK2 PLK3	1.16e-04	4	83	2	PS50078
Domain	POLO_box_1	PLK2 PLK3	1.16e-04	4	83	2	IPR033701
Domain	POLO_box_dom	PLK2 PLK3	1.93e-04	5	83	2	IPR000959
Domain	Bromodomain_CS	BAZ2A CECR2 BRPF1	2.04e-04	26	83	3	IPR018359
Domain	IQ	MYO5A MYO5B OBSCN MYO5C	2.81e-04	71	83	4	PF00612
Domain	IQ	MYO5A MYO5B OBSCN MYO5C	4.65e-04	81	83	4	SM00015
Domain	BROMODOMAIN_1	BAZ2A CECR2 BRPF1	5.90e-04	37	83	3	PS00633
Domain	Myosin_head_motor_dom	MYO5A MYO5B MYO5C	6.38e-04	38	83	3	IPR001609
Domain	Bromodomain	BAZ2A CECR2 BRPF1	6.38e-04	38	83	3	PF00439
Domain	MYOSIN_MOTOR	MYO5A MYO5B MYO5C	6.38e-04	38	83	3	PS51456
Domain	Myosin_head	MYO5A MYO5B MYO5C	6.38e-04	38	83	3	PF00063
Domain	MYSc	MYO5A MYO5B MYO5C	6.38e-04	38	83	3	SM00242
Domain	IQ_motif_EF-hand-BS	MYO5A MYO5B OBSCN MYO5C	6.93e-04	90	83	4	IPR000048
Domain	IQ	MYO5A MYO5B OBSCN MYO5C	7.84e-04	93	83	4	PS50096
Domain	BROMODOMAIN_2	BAZ2A CECR2 BRPF1	7.99e-04	41	83	3	PS50014
Domain	BROMO	BAZ2A CECR2 BRPF1	8.57e-04	42	83	3	SM00297
Domain	Bromodomain	BAZ2A CECR2 BRPF1	8.57e-04	42	83	3	IPR001487
Domain	-	BAZ2A CECR2 BRPF1	8.57e-04	42	83	3	1.20.920.10
Domain	Methyl_CpG_DNA-bd	SETDB1 BAZ2A	1.05e-03	11	83	2	IPR001739
Domain	MBD	SETDB1 BAZ2A	1.05e-03	11	83	2	PF01429
Domain	DNA-bd_dom	SETDB1 BAZ2A	1.05e-03	11	83	2	IPR016177
Domain	MBD	SETDB1 BAZ2A	1.05e-03	11	83	2	SM00391
Domain	MBD	SETDB1 BAZ2A	1.05e-03	11	83	2	PS50982
Domain	AT_hook	BAZ2A CECR2	2.25e-03	16	83	2	PF02178
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	PLK2 EFHB PLK3	3.59e-03	69	83	3	IPR020636
Domain	EF_HAND_2	FLG ACTN3 EFHB ZZEF1 MICU1	3.68e-03	231	83	5	PS50222
Domain	EF_hand_dom	FLG ACTN3 EFHB ZZEF1 MICU1	3.75e-03	232	83	5	IPR002048
Pubmed	Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.	MYO5A MYO5B MYO5C	1.41e-08	3	85	3	24339992
Pubmed	Structural insights into functional overlapping and differentiation among myosin V motors.	MYO5A MYO5B MYO5C	1.41e-08	3	85	3	24097982
Pubmed	Alternative splicing in class V myosins determines association with Rab10.	MYO5A MYO5B MYO5C	5.63e-08	4	85	3	19008234
Pubmed	Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.	MYO5A MAP2 MYO5B	2.80e-07	6	85	3	25673849
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	MYO5A MAP2 MATR3 GRIN2A EPB41L3 TRIM3 PRRC2B	1.66e-06	231	85	7	16452087
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SETDB1 NAA35 RASAL3 RIBC2 BAZ2A NACC1 CECR2 BRPF1 EPB41L3 ZZEF1 TRRAP PRRC2B KPNA1	3.10e-06	1116	85	13	31753913
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MIA3 MYO5A NACC1 MATR3 GRIN2A WDR1 EPB41L3 ADNP TTC3 TRIM3 PRRC2B KPNA1	3.90e-06	963	85	12	28671696
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO5A MYO5B MYO5C	5.03e-06	14	85	3	8022818
Pubmed	No association between ACTN3 R577X and ACE I/D polymorphisms and endurance running times in 698 Caucasian athletes.	ACTN3 ACE	5.90e-06	2	85	2	29298672
Pubmed	ACE I/D and ACTN3 R/X polymorphisms and muscle function and muscularity of older Caucasian men.	ACTN3 ACE	5.90e-06	2	85	2	20069311
Pubmed	The influence of genetic polymorphisms on performance and cardiac and hemodynamic parameters among Brazilian soccer players.	ACTN3 ACE	5.90e-06	2	85	2	28177711
Pubmed	Prevalence of alpha actinin-3 gene (ACTN3) R577X and angiotensin converting enzyme (ACE) insertion / deletion gene polymorphisms in national and amateur Turkish athletes.	ACTN3 ACE	5.90e-06	2	85	2	29729690
Pubmed	Genetic variation of the human ACE and ACTN3 genes and their association with functional muscle properties in Lithuanian elite athletes.	ACTN3 ACE	5.90e-06	2	85	2	21956137
Pubmed	Investigation on PLK2 and PLK3 substrate recognition.	PLK2 PLK3	5.90e-06	2	85	2	22828320
Pubmed	Association between Complex ACTN3 and ACE Gene Polymorphisms and Elite Endurance Sports in Koreans: A Case-Control Study.	ACTN3 ACE	5.90e-06	2	85	2	39336701
Pubmed	ACTN3 and ACE genotypes in elite Jamaican and US sprinters.	ACTN3 ACE	5.90e-06	2	85	2	20010124
Pubmed	Forkhead box o3a suppresses lipopolysaccharide-stimulated proliferation and inflammation in fibroblast-like synoviocytes through regulating tripartite motif-containing protein 3.	FOXO3 TRIM3	5.90e-06	2	85	2	30980385
Pubmed	Polymorphisms in ACE and ACTN3 Genes and Blood Pressure Response to Acute Exercise in Elite Male Athletes from Serbia.	ACTN3 ACE	5.90e-06	2	85	2	29269700
Pubmed	Cloning and characterization of a novel RING finger protein that interacts with class V myosins.	MYO5A TRIM3	5.90e-06	2	85	2	10391919
Pubmed	The influence of ACE ID and ACTN3 R577X polymorphisms on lower-extremity function in older women in response to high-speed power training.	ACTN3 ACE	5.90e-06	2	85	2	24313907
Pubmed	Distribution of performance-related gene polymorphisms (ACTN3 R577X and ACE ID) in different ethnic groups of the Indian Army.	ACTN3 ACE	5.90e-06	2	85	2	24114905
Pubmed	Association of angiotensin-converting enzyme I/D and α-actinin-3 R577X genotypes with metabolic syndrome risk factors in Korean children.	ACTN3 ACE	5.90e-06	2	85	2	26483160
Pubmed	Genetic ACE I/D and ACTN3 R577X polymorphisms and adolescent idiopathic scoliosis.	ACTN3 ACE	5.90e-06	2	85	2	27819725
Pubmed	Muscle Work and Its Relationship with ACE and ACTN3 Polymorphisms Are Associated with the Improvement of Explosive Strength.	ACTN3 ACE	5.90e-06	2	85	2	34440352
Pubmed	Combination of ACTN3 R577X and ACE I/D polymorphisms as a tool for prediction of obesity risk in children.	ACTN3 ACE	5.90e-06	2	85	2	32873907
Pubmed	A Pilot Study on the Prediction of Non-Contact Muscle Injuries Based on ACTN3 R577X and ACE I/D Polymorphisms in Professional Soccer Athletes.	ACTN3 ACE	5.90e-06	2	85	2	36360246
Pubmed	Human myosin-Vc is a novel class V myosin expressed in epithelial cells.	MYO5A MYO5C	5.90e-06	2	85	2	11870218
Pubmed	Effect of angiotensin I-converting enzyme and α-actinin-3 gene polymorphisms on sport performance.	ACTN3 ACE	5.90e-06	2	85	2	24566537
Pubmed	The individual and combined influence of ACE and ACTN3 genotypes on muscle phenotypes before and after strength training.	ACTN3 ACE	5.90e-06	2	85	2	23384112
Pubmed	Higher frequency of the ACTN3 R allele + ACE DD genotype in Japanese elite wrestlers.	ACTN3 ACE	5.90e-06	2	85	2	22996021
Pubmed	Single and combined influence of ACE and ACTN3 genotypes on muscle phenotypes in octogenarians.	ACTN3 ACE	5.90e-06	2	85	2	22045415
Pubmed	Does the ACE I/D polymorphism, alone or in combination with the ACTN3 R577X polymorphism, influence muscle power phenotypes in young, non-athletic adults?	ACTN3 ACE	5.90e-06	2	85	2	20734058
Pubmed	ACTN3 R577X and ACE I/D gene variants influence performance in elite sprinters: a multi-cohort study.	ACTN3 ACE	5.90e-06	2	85	2	27075997
Pubmed	Endurance performance: genes or gene combinations?	ACTN3 ACE	5.90e-06	2	85	2	18651373
Pubmed	Human angiotensin-converting enzyme I/D and alpha-actinin 3 R577X genotypes and muscle functional and contractile properties.	ACTN3 ACE	5.90e-06	2	85	2	18676575
Pubmed	The association of the ACTN3 R577X and ACE I/D polymorphisms with athlete status in football: a systematic review and meta-analysis.	ACTN3 ACE	5.90e-06	2	85	2	32856541
Pubmed	ACE I/D and ACTN3 R/X polymorphisms as potential factors in modulating exercise-related phenotypes in older women in response to a muscle power training stimuli.	ACTN3 ACE	5.90e-06	2	85	2	22855367
Pubmed	Genetic markers and explosive leg-muscle strength in elite Italian soccer players.	ACTN3 ACE	5.90e-06	2	85	2	22648472
Pubmed	In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain.	PLK2 PLK3	5.90e-06	2	85	2	24128992
Pubmed	The association of sport performance with ACE and ACTN3 genetic polymorphisms: a systematic review and meta-analysis.	ACTN3 ACE	5.90e-06	2	85	2	23358679
Pubmed	Is there an ACE ID - ACTN3 R577X polymorphisms interaction that influences sprint performance?	ACTN3 ACE	5.90e-06	2	85	2	20013558
Pubmed	Association analysis of ACE and ACTN3 in elite Caucasian and East Asian swimmers.	ACTN3 ACE	5.90e-06	2	85	2	23190598
Pubmed	Exome sequencing identifies GRIN2A as frequently mutated in melanoma.	GRIN2A TRRAP	5.90e-06	2	85	2	21499247
Pubmed	Moderate exercise reveals the influence of ACTN3 R577X and ACE I/D polymorphisms on physical performance in non-athlete active subjects.	ACTN3 ACE	5.90e-06	2	85	2	36220449
Pubmed	Association between ACE and ACTN3 genes polymorphisms and athletic performance in elite and sub-elite Chinese youth male football players.	ACTN3 ACE	5.90e-06	2	85	2	36992938
Pubmed	ACTN3/ACE genotypes and mitochondrial genome in professional soccer players performance.	ACTN3 ACE	5.90e-06	2	85	2	28337894
Pubmed	ACE and ACTN3 genes and muscle phenotypes in nonagenarians.	ACTN3 ACE	5.90e-06	2	85	2	20148371
Pubmed	Identification of the Isoform-specific Interactions between the Tail and the Head of Class V Myosin.	MYO5A MYO5C	5.90e-06	2	85	2	26912658
Pubmed	Interaction of transcription factor FoxO3 with histone acetyltransferase complex subunit TRRAP modulates gene expression and apoptosis.	FOXO3 TRRAP	5.90e-06	2	85	2	35151693
Pubmed	Association of ACTN3 R577X but not ACE I/D gene variants with elite rugby union player status and playing position.	ACTN3 ACE	5.90e-06	2	85	2	26757799
Pubmed	Individual and Combined Influence of ACE and ACTN3 Genes on Muscle Phenotypes in Polish Athletes.	ACTN3 ACE	5.90e-06	2	85	2	28195972
Pubmed	Human transcription factor protein interaction networks.	FLG SETDB1 RBM12 L3MBTL2 MYO5A NACC1 MATR3 TBXT WDR1 ADNP TRRAP PRRC2B MYO5C RAD21	9.08e-06	1429	85	14	35140242
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	L3MBTL2 MYO5B BAZ2A MATR3 ZDBF2 EPB41L3 ADNP KPNA1 RAD21	1.31e-05	583	85	9	29844126
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RBM12 L3MBTL2 BAZ2A NACC1 MATR3 WDR1 EPB41L3 ADNP PUS7 PRRC2B RAD21	1.72e-05	934	85	11	33916271
Pubmed	Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages.	PLK2 PLK3	1.77e-05	3	85	2	11039900
Pubmed	Performance enhancing genetic variants, oxygen uptake, heart rate, blood pressure and body mass index of elite high altitude mountaineers.	ACTN3 ACE	1.77e-05	3	85	2	24058088
Pubmed	Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.	MYO5A MYO5B	1.77e-05	3	85	2	28939769
Pubmed	The association of ACE, ACTN3 and PPARA gene variants with strength phenotypes in middle school-age children.	ACTN3 ACE	1.77e-05	3	85	2	22983821
Pubmed	The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity.	PLK2 PLK3	1.77e-05	3	85	2	10523297
Pubmed	Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.	MYO5A MYO5B	1.77e-05	3	85	2	24508725
Pubmed	Genetic polymorphisms in the angiotensin converting enzyme, actinin 3 and paraoxonase 1 genes in women with diabetes and hypertension.	ACTN3 ACE	1.77e-05	3	85	2	37948561
Pubmed	ACE and ACTN3 genotypes in older women: muscular phenotypes.	ACTN3 ACE	1.77e-05	3	85	2	21072744
Pubmed	The temporal and spatial expression pattern of myosin Va, Vb and VI in the mouse ovary.	MYO5A MYO5B	1.77e-05	3	85	2	16713372
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	COL8A1 NAA35 FBXL18 L3MBTL2 MYO5A ACAT2 BAZ2A MATR3 WDR1 EPB41L3 ADNP TRRAP KPNA1	2.41e-05	1353	85	13	29467282
Pubmed	Pathogenicity of lupus anti-ribosomal P antibodies: role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model.	GRIN2A ZZEF1	3.53e-05	4	85	2	25709106
Pubmed	Facilitation of dendritic mRNA transport by CPEB.	MAP2 KIF1B	3.53e-05	4	85	2	12629046
Pubmed	Identification and assessment of PLK1/2/3/4 in lung adenocarcinoma and lung squamous cell carcinoma: Evidence from methylation profile.	PLK2 PLK3	3.53e-05	4	85	2	34080290
Pubmed	Structural basis of myosin V Rab GTPase-dependent cargo recognition.	MYO5A MYO5B	3.53e-05	4	85	2	24248336
Pubmed	ACE I/D, ACTN3 R577X, PPARD T294C and PPARGC1A Gly482Ser polymorphisms and physical fitness in Taiwanese late adolescent girls.	ACTN3 ACE	3.53e-05	4	85	2	22247001
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	SORT1 FOXO3 L3MBTL2 NACC1 DRAP1 ADNP TRRAP GAA TRIM3 KPNA1	4.63e-05	857	85	10	25609649
Pubmed	Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice.	FOXO3 MYO5A MYO5B	5.45e-05	30	85	3	28077597
Pubmed	Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.	MAP2 WDR1 EPB41L3 TRIM3	5.52e-05	84	85	4	19165527
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	MYO5B MATR3 ZDBF2 TRRAP KPNA1 RAD21	5.65e-05	272	85	6	31010829
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	L3MBTL2 NACC1 CXXC5 ADNP TRRAP	5.78e-05	167	85	5	20362541
Pubmed	Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.	PLK2 PLK3	5.87e-05	5	85	2	19597481
Pubmed	Phosphorylation of synucleins by members of the Polo-like kinase family.	PLK2 PLK3	5.87e-05	5	85	2	19889641
Pubmed	Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG.	GRIN2A ZZEF1	5.87e-05	5	85	2	33158444
Pubmed	CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling.	MYO5A TRIM3	5.87e-05	5	85	2	15772161
Pubmed	Genotype modulators of clinical severity in McArdle disease.	ACTN3 ACE	5.87e-05	5	85	2	17630210
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NAA35 FRAS1 MIA3 L3MBTL2 MYO5A MAP2 BAZ2A DNAJC27 EPB41L3 TTC3 PUS7 RAD21 MICU1	6.36e-05	1487	85	13	33957083
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETDB1 FRAS1 AVL9 BAZ2A KIF1B DAAM2 PRRC2B	6.43e-05	407	85	7	12693553
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FOXO3 MIA3 MYO5A MAP2 KIF1B OBSCN MKLN1 SCNN1A CXXC5 TTC3 TRRAP KPNA1 MICU1	6.44e-05	1489	85	13	28611215
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 SETDB1 PLK2 MYO5A KIF1B MKLN1 CXXC5 DAAM2 PJA1 TTC3 KPNA1 MICU1	6.71e-05	1285	85	12	35914814
Pubmed	World-class performance in lightweight rowing: is it genetically influenced? A comparison with cyclists, runners and non-athletes.	ACTN3 ACE	8.80e-05	6	85	2	18801770
Pubmed	Can we identify a power-oriented polygenic profile?	ACTN3 ACE	8.80e-05	6	85	2	20044471
Pubmed	Is there an optimum endurance polygenic profile?	ACTN3 ACE	8.80e-05	6	85	2	19237423
Pubmed	Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis.	UNCX TBXT	1.23e-04	7	85	2	37024462
Pubmed	The physical association and phosphorylation of Cdc25C protein phosphatase by Prk.	PLK2 PLK3	1.23e-04	7	85	2	10557092
Pubmed	Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus.	MAP2 GRIN2A	1.23e-04	7	85	2	12103442
Pubmed	Does the polygenic profile determine the potential for becoming a world-class athlete? Insights from the sport of rowing.	ACTN3 ACE	1.23e-04	7	85	2	19422651
Pubmed	A new gain-of-function mouse line to study the role of Wnt3a in development and disease.	UNCX TBXT	1.23e-04	7	85	2	27411055
Pubmed	The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo.	UNCX TBXT	1.23e-04	7	85	2	19056682
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	SETDB1 COL8A1 MYO5B MATR3 DRAP1 EPB41L3 PRRC2B KPNA1	1.23e-04	608	85	8	16713569
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	L3MBTL2 BAZ2A NACC1 BRPF1 ADNP TRRAP KPNA1 RAD21	1.23e-04	608	85	8	36089195
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	MYO5A MAP2 MYO5B KIF1B GRIN2A EPB41L3 TRRAP TRIM3	1.42e-04	621	85	8	22794259
Pubmed	Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.	SETDB1 KIF1B RAD21	1.51e-04	42	85	3	7584044
Pubmed	Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.	L3MBTL2 TRRAP RAD21	1.51e-04	42	85	3	29028833
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	NAA35 MIA3 MATR3 BRPF1 DAAM2 ALDH1L1 WDR1 ZZEF1 ACE	1.59e-04	807	85	9	30575818
Pubmed	BRACHYURY directs histone acetylation to target loci during mesoderm development.	UNCX TBXT	1.64e-04	8	85	2	29141987
Pubmed	Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis.	UNCX TBXT	1.64e-04	8	85	2	19660449
Interaction	PIPSL interactions	NSUN3 L3MBTL2 MYO5A KIF1B ZDBF2 PUS7 MYO5C RAD21	9.40e-06	252	83	8	int:PIPSL
Cytoband	15q21	MYO5A MYO5C	1.84e-04	11	85	2	15q21
Cytoband	5q31.2	MATR3 CXXC5	1.24e-03	28	85	2	5q31.2
Cytoband	6p21.2	C6orf89 DAAM2	2.05e-03	36	85	2	6p21.2
GeneFamily	Myosins, class V	MYO5A MYO5B MYO5C	2.81e-08	3	56	3	1100
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	SETDB1 BAZ2A	5.09e-04	11	56	2	1025
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B CECR2 SCNN1A DAAM2 EPB41L3 MYO5C	4.93e-08	177	85	7	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL5A2 COL8A1 FRAS1 BHLHE22 SCNN1A ALDH1L1	5.93e-07	158	85	6	c8af8964a140acb2987e3b4906d72c546108d229
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B CECR2 SCNN1A EPB41L3 MYO5C	1.23e-06	179	85	6	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B CECR2 SCNN1A EPB41L3 MYO5C	1.31e-06	181	85	6	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B CECR2 SCNN1A EPB41L3 MYO5C	1.44e-06	184	85	6	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B CECR2 SCNN1A EPB41L3 MYO5C	1.49e-06	185	85	6	c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B CECR2 SCNN1A EPB41L3 MYO5C	1.54e-06	186	85	6	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B CECR2 SCNN1A EPB41L3 MYO5C	1.54e-06	186	85	6	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B CECR2 SCNN1A EPB41L3 MYO5C	1.58e-06	187	85	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL8A1 MAP2 MYO5B SCNN1A EPB41L3 MYO5C	2.02e-06	195	85	6	a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	PRSS35 FRAS1 MYO5B SCNN1A EPB41L3 MYO5C	2.21e-06	198	85	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	PRSS35 FRAS1 MYO5B SCNN1A EPB41L3 MYO5C	2.21e-06	198	85	6	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL8A1 WWC3 MYO5B CECR2 SCNN1A MYO5C	2.27e-06	199	85	6	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PRSS35 DPY19L3 MYO5B OBSCN ZNF541	3.72e-06	122	85	5	37612ad087d9c11d4a3466244ab36224de31930b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS35 DPY19L3 MYO5B OBSCN IL17RA	1.48e-05	162	85	5	4d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	COL8A1 MAP2 MYO5B EPB41L3 MYO5C	2.09e-05	174	85	5	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	15-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	MYO5B RIBC2 CFAP74 DEUP1 MYO5C	2.33e-05	178	85	5	d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	COL8A1 MAP2 MYO5B SCNN1A MYO5C	2.39e-05	179	85	5	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 MYO5B SCNN1A EPB41L3 TRIM3	2.59e-05	182	85	5	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 MYO5B SCNN1A EPB41L3 TRIM3	2.59e-05	182	85	5	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL8A1 MAP2 MYO5B SCNN1A MYO5C	2.66e-05	183	85	5	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	18-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	MYO5B RIBC2 CFAP74 DEUP1 MYO5C	2.66e-05	183	85	5	a75cda2131755931117c387f2e0ae3394efa8e80
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	COL8A1 MAP2 MYO5B SCNN1A MYO5C	2.66e-05	183	85	5	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B CECR2 SCNN1A EPB41L3 MYO5C	2.66e-05	183	85	5	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL8A1 MAP2 MYO5B SCNN1A MYO5C	2.73e-05	184	85	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B CECR2 SCNN1A EPB41L3 MYO5C	2.73e-05	184	85	5	7cc5796557379c3d1db078c1aeda40659c6e401c
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B CECR2 SCNN1A EPB41L3 MYO5C	2.73e-05	184	85	5	cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL8A1 MAP2 MYO5B SCNN1A MYO5C	2.73e-05	184	85	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL8A1 MAP2 MYO5B EPB41L3 MYO5C	2.80e-05	185	85	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL8A1 PLK2 ALDH1L1 ITIH5 MYO5C	2.80e-05	185	85	5	fd1911b57927c03470f9387962ca9581e5643fb3
ToppCell	facs-Large_Intestine-Distal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL8A1 PLK2 ALDH1L1 ITIH5 MYO5C	2.80e-05	185	85	5	7a18d525de6f874924bfc61b9666b307da86421a
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 MYO5B SCNN1A EPB41L3 MYO5C	2.95e-05	187	85	5	ff26a533d310126521efe1d05cf8b9d32e524550
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	COL8A1 MAP2 MYO5B SCNN1A MYO5C	2.95e-05	187	85	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	COL5A2 COL8A1 WWC3 AVL9 ADNP	3.02e-05	188	85	5	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXO3 COL5A2 OBSCN DAAM2 GRIN2A	3.02e-05	188	85	5	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	SupraBC-Differ-KC\|World / shred by cell class for mouse tongue	SORT1 SERPINB13 MAP2 MYO5B SCNN1A	3.10e-05	189	85	5	6412741b88e241304033b41effca0c77a374d907
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYO5A KIF1B DAAM2 SRGAP2B EPB41L3	3.18e-05	190	85	5	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	facs-Tongue-nan-3m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 SERPINB13 MAP2 MYO5B SCNN1A	3.18e-05	190	85	5	719a5cecc3e8001ca9c38165258b5ff9c800713a
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A2 COL8A1 MAP2 ACE ITIH5	3.26e-05	191	85	5	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	COL8A1 MYO5B CECR2 SCNN1A MYO5C	3.34e-05	192	85	5	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPB41L3 TTC3 GAA PUS7 ITIH5	3.34e-05	192	85	5	03dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	MYO5A DAAM2 IL17RA SRGAP2B EPB41L3	3.34e-05	192	85	5	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 FRAS1 MYO5B SCNN1A MYO5C	3.34e-05	192	85	5	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 MYO5B SCNN1A EPB41L3 TRIM3	3.34e-05	192	85	5	790282d4232311df3dac4ad97c80fc53443beccc
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 MYO5B SCNN1A EPB41L3 TRIM3	3.34e-05	192	85	5	b2d9bffccd6264b4f12d88a0780646ee0b41969f
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	COL5A2 COL8A1 FRAS1 MAP2 CECR2	3.34e-05	192	85	5	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PRSS35 COL8A1 MAP2 NAB1 DAAM2	3.42e-05	193	85	5	ba6eb29478d16589172f48f9992e5116328c81d6
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PRSS35 COL8A1 MYO5B ASXL3 DAAM2	3.69e-05	196	85	5	57df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-AT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL8A1 MAP2 MYO5B SCNN1A MYO5C	3.87e-05	198	85	5	54228dd9a50616d2022712d162a419ed0327cabd
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FRAS1 MYO5B SCNN1A EPB41L3 MYO5C	3.87e-05	198	85	5	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MAP2 BHLHE22 DAAM2 GRIN2A ITIH5	3.87e-05	198	85	5	0f1feed8a37293ae02465909f99548ab58dc7ce5
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_alveolar-AT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL8A1 MAP2 MYO5B SCNN1A MYO5C	3.96e-05	199	85	5	aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK3 COL5A2 COL8A1 KCNA7 ITIH5	3.96e-05	199	85	5	e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FRAS1 MYO5B SCNN1A EPB41L3 MYO5C	3.96e-05	199	85	5	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	Neuron\|World / Primary Cells by Cluster	PLK2 MAP2 ASXL3 BHLHE22 TTC3	3.96e-05	199	85	5	1f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCell	Neuron-Postmitotic\|World / Primary Cells by Cluster	PLK2 MAP2 ASXL3 BHLHE22 TTC3	3.96e-05	199	85	5	1973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	PLK2 MAP2 BHLHE22 EPB41L3 TTC3	4.06e-05	200	85	5	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	MYO5B CECR2 SCNN1A EPB41L3 MYO5C	4.06e-05	200	85	5	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DPY19L3 MIA3 MYO5B SCNN1A MYO5C	4.06e-05	200	85	5	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PLK2 DPY19L3 TRIM3 PUS7 ZNF541	4.06e-05	200	85	5	a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FRAS1 MYO5B SCNN1A EPB41L3 MYO5C	4.06e-05	200	85	5	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	PLK2 MAP2 BHLHE22 EPB41L3 TTC3	4.06e-05	200	85	5	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PRSS35 COL5A2 COL8A1 DAAM2 SLC36A2	4.06e-05	200	85	5	3c898e81444b001835c3f1bbc68183078701b135
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	PLK2 MAP2 ASXL3 BHLHE22 TTC3	4.06e-05	200	85	5	306926cb7a847871641f02e03d52dc56fd55711c
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PRSS35 COL5A2 COL8A1 DAAM2 SLC36A2	4.06e-05	200	85	5	3eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DPY19L3 MIA3 MYO5B SCNN1A MYO5C	4.06e-05	200	85	5	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	Control-B_naive-4\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PLK2 RIBC2 SCNN1A DAAM2	4.72e-05	104	85	4	5f72aa686b0fb83d401621e1b9d9c69e56105570
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FOXO3 MYO5B CECR2 SCNN1A	1.12e-04	130	85	4	eb16a8f8f62add5fdd29c78d4608b6d1a06767f1
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_D\|E18.5-samps / Age Group, Lineage, Cell class and subclass	PRSS35 MAP2 YRDC ITIH5	1.90e-04	149	85	4	dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS35 MYO5B OBSCN IL17RA	2.00e-04	151	85	4	f50c5ae9dae507df750df25e151b58685fec70ce
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS35 MYO5B OBSCN IL17RA	2.15e-04	154	85	4	12cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS35 MYO5B OBSCN IL17RA	2.26e-04	156	85	4	fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SORT1 FRAS1 PLK2 BHLHE22	2.55e-04	161	85	4	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS35 DPY19L3 OBSCN IL17RA	2.61e-04	162	85	4	58da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	COL8A1 DPY19L3 TRRAP GAA	2.68e-04	163	85	4	63b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell	Ciliated_cells-A-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	RIBC2 CFAP74 EFHB DEUP1	2.68e-04	163	85	4	43194c6127df1ce3d29242f719645de3c11fd7c0
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DPY19L3 OBSCN ZNF541 MYO5C	2.68e-04	163	85	4	218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DPY19L3 OBSCN IL17RA ALDH1L1	2.68e-04	163	85	4	b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ALDH1L1 EPB41L3 SLC36A2 SLC5A2	3.00e-04	168	85	4	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAB1 SCNN1A IL17RA ACE	3.00e-04	168	85	4	4b5be7c6662eceddf90a65015f12908278d1664e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAB1 SCNN1A IL17RA ACE	3.00e-04	168	85	4	689c41f6e9f65381570991cc311cba49a57ec955
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAB1 SCNN1A IL17RA ACE	3.07e-04	169	85	4	411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCell	droplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAB1 SCNN1A IL17RA ACE	3.07e-04	169	85	4	39b1acfd099abb9de18c29c05c7a67709ea76775
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL8A1 BAZ2A DAAM2 GRIN2A	3.21e-04	171	85	4	2a34685f7d83d1cf9a88d304173cbca868c5f9fd
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Deuterosomal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MYO5B RIBC2 CFAP74 DEUP1	3.21e-04	171	85	4	52aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	SORT1 DPY19L3 MYO5B PRRC2B	3.35e-04	173	85	4	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	COL8A1 MAP2 MYO5B SCNN1A	3.35e-04	173	85	4	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DPY19L3 FBXL18 DNAJC27 DRAP1	3.43e-04	174	85	4	a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 SCNN1A CFAP74 MYO5C	3.43e-04	174	85	4	d927504d27b07bbc580bf57c60b383bd28624652
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 FBXL18 ITIH5 RAD21	3.50e-04	175	85	4	0801cccec6915aefc135262fc74580280fd51aa5
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 FBXL18 ITIH5 RAD21	3.50e-04	175	85	4	09163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCell	P03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FRAS1 KCNA7 SCNN1A TRIM3	3.58e-04	176	85	4	f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A2 COL8A1 PLK2 ACE	3.58e-04	176	85	4	27e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A2 COL8A1 PLK2 ACE	3.58e-04	176	85	4	d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CECR2 SCNN1A EPB41L3 ITIH5	3.66e-04	177	85	4	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	AT1_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	COL8A1 MAP2 SCNN1A MYO5C	3.66e-04	177	85	4	3128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A2 MAP2 DAAM2 ITIH5	3.66e-04	177	85	4	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A2 MAP2 DAAM2 ITIH5	3.66e-04	177	85	4	3645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL5A2 OBSCN DAAM2 ITIH5	3.74e-04	178	85	4	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	Control-Epithelial_alveolar-AT_1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B SCNN1A EPB41L3 MYO5C	3.74e-04	178	85	4	aa7d43c655df493f1330a5001efaa484e4a19f69
Computational	Neighborhood of UBE2N	FOXO3 BAZ2A NAB1 CXXC5 ADNP PRRC2B	1.41e-04	154	56	6	GCM_UBE2N
Disease	uric acid measurement	FRAS1 NSUN3 UNCX C6orf89 RDH14 TBXT WDR1 DRAP1 EPB41L3 PRRC2B	8.31e-06	610	83	10	EFO_0004761
Disease	focal segmental glomerulosclerosis 1 (implicated_via_orthology)	ACTN3 ACE	7.77e-05	5	83	2	DOID:0111128 (implicated_via_orthology)
Disease	schizophrenia (is_marker_for)	SETDB1 MAP2 ACE	2.62e-04	44	83	3	DOID:5419 (is_marker_for)
Disease	body fat distribution	DOCK3 UNCX KIF1B CXXC5 DNAJC27	2.69e-04	202	83	5	EFO_0004341
Disease	cesarean section, intelligence	C6orf89 GRIN2A	5.07e-04	12	83	2	EFO_0004337, EFO_0009636
Disease	1-stearoyl-2-linoleoyl-GPI (18:0/18:2) measurement	MYO5B ZPR1	5.98e-04	13	83	2	EFO_0800413
Disease	Coronary Arteriosclerosis	SORT1 MIA3 ACE	8.27e-04	65	83	3	C0010054
Disease	Coronary Artery Disease	SORT1 MIA3 ACE	8.27e-04	65	83	3	C1956346
Disease	Pre-Eclampsia	SCNN1A ACE	9.14e-04	16	83	2	C0032914
Disease	ischemia (implicated_via_orthology)	SCNN1A ADNP	1.03e-03	17	83	2	DOID:326 (implicated_via_orthology)
Disease	bipolar disorder	PRSS35 DPY19L3 MAP2 MKLN1 GRIN2A ACTN3 PUS7	1.21e-03	577	83	7	MONDO_0004985
Disease	nephrotic syndrome (implicated_via_orthology)	SCNN1A ACE	2.07e-03	24	83	2	DOID:1184 (implicated_via_orthology)
Disease	large artery stroke, coronary artery disease	C6orf89 ZPR1	2.25e-03	25	83	2	EFO_0001645, EFO_0005524
Disease	Left Ventricular Hypertrophy	ACE GAA	2.25e-03	25	83	2	C0149721
Disease	childhood onset asthma	FLG MIA3 NSUN3 C6orf89 MKLN1	2.55e-03	334	83	5	MONDO_0005405

Protein segments in the cluster

Peptide	Gene	Start	Entry
QFDNMTDGVAEPMHG	ADNP	1076	Q9H2P0
EDGNGKIMPASTFDM	CARNMT1	141	Q8N4J0
EGGSDEHDINFLMKM	ACE	1041	P12821
MEMEANDHFNFTGLP	BAZ2A	1	Q9UIF9
MERGMHLGAAAAGED	BHLHE22	1	Q8NFJ8
KNPDDPDMVDVFMDH	FLG	46	P20930
LLDIANGHMMDGPGE	DPY19L3	656	Q6ZPD9
NTHLKGMMGDLDPGE	DEUP1	426	Q05D60
FHRAMMKHFPGEDGD	CECR2	531	Q9BXF3
MKEGDEVGGTAHTMP	ASXL3	1996	Q9C0F0
PDMQGDGEDNHMDGD	DRAP1	91	Q14919
NEKGMPTGEAMVAFE	RBM12	891	Q9NTZ6
MGFMNSFLEEHGPAM	RASAL3	661	Q86YV0
EDEGFMGMSPLLQAH	ADIPOR2	71	Q86V24
HDDMDEDDNVSMGGP	RAD21	261	O60216
ALMHFGEHDSKMQPD	DAAM2	941	Q86T65
HGKPVGDLFTAAMNM	IL17RA	471	Q96F46
ELDGRKMGDAQPEMF	NSUN3	191	Q9H649
DHQVMYIMKEDPGAG	FRAS1	2111	Q86XX4
HHANDSDLPMEEGMA	METAP1D	266	Q6UB28
PDNDTGHTMGDPFML	MATR3	331	P43243
DGLEEAHGMSAAMGP	ITIH5	631	Q86UX2
LFNMDCPNHGFKVGM	L3MBTL2	526	Q969R5
MIGHIFEMNDDDPHK	NAB1	231	Q13506
LAEMKQELGPHGNME	DNAJC27	111	Q9NZQ0
GKMVMEGFSEEIGNH	KIF1B	1096	O60333
AFKMFDLNGDGEVDM	MICU1	226	Q9BPX6
SGMQKFMGEDLNFHE	RIBC2	141	Q9H4K1
HMAGLAEYPMQGELA	CXXC5	236	Q7LFL8
EMKQQEGPMFSHTFG	OBSCN	4891	Q5VST9
EGEEAGMFSHVDMQP	KCNA7	406	Q96RP8
GSMGDAPEDLYHHMQ	DOCK3	1701	Q8IZD9
MAGNHGEDAAMKTEE	AVL9	281	Q8NBF6
AALGDIMGHYDESMP	COL5A2	1231	P05997
DGLAMGKEMPHLQYG	COL8A1	66	P27658
DMVAEFHDQVPFDGM	GAA	501	P10253
MNMEIGHPHEGKDDL	EFHB	1	Q8N7U6
MHKMPDLFIIGSGEA	C6orf89	276	Q6UWU4
GEHGFDNKDMDMKTI	ENPP7	351	Q6UWV6
VMVHGQDEPAFMDDG	SCNN1A	351	P37088
CQHMMFVEGGDPLDV	CFAP74	1476	Q9C0B2
GMTPAEAEMHFLENA	EPB41L3	276	Q9Y2J2
VMGHEKFPSDLDLDM	FOXO3	601	O43524
ANDDMVFMHVDEPGD	SORT1	356	Q99523
LGGAMEEMQPLHEDN	MIA3	1051	Q5JRA6
DGGPKLVFDHQMCMD	MKLN1	381	Q9UL63
GFHEAQISNMEMAPG	KPNA1	66	P52294
DDDDMHPAAAGMADG	FBXL18	11	Q96ME1
FADMMKHGLTEADVG	PUS7	101	Q96PZ0
MDYGDTVMHGLEANP	SLC36A2	121	Q495M3
KFEFQPHMGDMASQL	SRGAP2B	341	P0DMP2
SPDNEHFASGGMDMM	WDR1	541	O75083
MKTEDGFEMQFGVNH	RDH14	151	Q9HBH5
EGDDFEDKKNMTGPM	SETDB1	1141	Q15047
AEKMGIDFETGMHIP	BRPF1	736	P55201
HFDRKQNGMMEPDDF	ACTN3	771	Q08043
DHMFIAKEESFGPVM	ALDH1L1	796	O75891
HYQDCMEDMDGRAPG	ADPRH	86	P54922
MEDMDGRAPGGASVH	ADPRH	91	P54922
KPGGSLDGMDMLHNF	NLN	671	Q9BYT8
ASYMEQHLMKGGDLP	PLK3	536	Q9H4B4
EGNMKAHFIMDDPAG	ZPR1	396	O75312
QNDTTKGDHPIMMGF	NAA35	286	Q5VZE5
AGGMENMSKAPHLAY	ACAT2	116	Q9BWD1
MEEHTEAGSAPEMGA	SLC5A2	1	P31639
AAMGMGDAFSEHKAD	SERPINB13	301	Q9UIV8
KMPGGMIHFSGFDND	PRSS35	301	Q8N3Z0
PAALHDFEMSGNMSD	SOGA1	1091	O94964
LMDMNCESHGPEMGF	ZDBF2	656	Q9HCK1
QFLEEHGPLDMSNKM	TTC3	1116	P53804
REPSQMEMKGFHFAD	PRRC2B	2126	Q5JSZ5
HKEMMEEPGDSQQPG	TBXT	226	O15178
QEADAFMGVESGHMK	MAP2	1086	P11137
PEGHGDDHEMVNMEF	ZZEF1	1816	O43149
SHYMEENLMDGGDLP	PLK2	576	Q9NYY3
DNDSGHELMQPGVFM	PJA1	476	Q8NG27
MFHSEENGSKGMDPL	TRRAP	1076	Q9Y4A5
AHASAMGDEDLPGMA	WWC3	501	Q9ULE0
MEAMQQAPDGAHDPE	TRIM3	86	O75382
HIGSMAMGQEKDGEE	ZNF541	926	Q9H0D2
MMDGRLLEHPHAQFG	UNCX	1	A6NJT0
DHAFMQDLAQMFEGP	YRDC	176	Q86U90
NMGDMDPHIFAVAEE	MYO5A	131	Q9Y4I1
NMGDMDPHIFAVAEE	MYO5B	131	Q9ULV0
SGQNMGDMDPHIFAV	MYO5C	126	Q9NQX4
TGKIEPDMMGVEHGF	NACC1	496	Q96RE7
PDMMGVEHGFETASH	NACC1	501	Q96RE7
GIHGGASMIMADKDP	GRIN2A	126	Q12879