Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone methyltransferase activity

NSD1 SETDB1 KMT5B PRDM13 METTL22

2.99e-05711015GO:0042054
GeneOntologyMolecularFunctionhistone modifying activity

NSD1 CDY1 SETDB1 BRCA2 KMT5B PRDM13 METTL22

1.64e-042291017GO:0140993
GeneOntologyMolecularFunctionprotein methyltransferase activity

NSD1 SETDB1 KMT5B PRDM13 METTL22

1.77e-041031015GO:0008276
GeneOntologyMolecularFunctioncytoskeletal anchor activity

ANK2 ANK3 MAP1A

2.35e-04241013GO:0008093
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

NSD1 SETDB1 KMT5B METTL22

3.92e-04681014GO:0016279
GeneOntologyMolecularFunctioncytoskeletal protein binding

NPHS1 FLNB ANK2 ANK3 MAP1A ANXA8L1 CEACAM8 FXYD5 ANXA8 C10orf90 ADGRV1 TTBK2 BRCA2 NAV3 FHDC1

4.06e-04109910115GO:0008092
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

NSD1 SETDB1 KMT5B METTL22

4.14e-04691014GO:0016278
GeneOntologyMolecularFunctionspectrin binding

NPHS1 ANK2 ANK3

6.71e-04341013GO:0030507
GeneOntologyMolecularFunctionphosphorylation-dependent protein binding

ANK2 ANK3

1.11e-03101012GO:0140031
GeneOntologyMolecularFunctionhistone H4K20 methyltransferase activity

NSD1 KMT5B

1.11e-03101012GO:0042799
GeneOntologyMolecularFunctionchromatin binding

NSD1 MSL1 NR3C1 PHF21A SETDB1 ARID1B TOX4 SALL1 KMT5B ATAD2B PRDM13

1.28e-0373910111GO:0003682
GeneOntologyBiologicalProcesschromatin remodeling

PPM1D NSD1 MSL1 NR3C1 CDY1 YEATS2 SETDB1 ARID1B BRCA2 UBR5 KMT5B ATAD2B PRDM13 METTL22

1.50e-0574110114GO:0006338
GeneOntologyBiologicalProcessslit diaphragm assembly

NPHS1 PTPRO

2.37e-0521012GO:0036060
GeneOntologyBiologicalProcesschromatin organization

PPM1D NSD1 MSL1 NR3C1 PHF21A CDY1 YEATS2 SETDB1 ARID1B BRCA2 UBR5 KMT5B ATAD2B PRDM13 METTL22

2.98e-0589610115GO:0006325
GeneOntologyBiologicalProcessfiltration diaphragm assembly

NPHS1 PTPRO

7.10e-0531012GO:0036058
GeneOntologyBiologicalProcessnegative regulation of phospholipase A2 activity

ANXA8L1 ANXA8

7.10e-0531012GO:1900138
GeneOntologyBiologicalProcessprotein-DNA complex organization

PPM1D NSD1 MSL1 NR3C1 PHF21A CDY1 YEATS2 SETDB1 ARID1B BRCA2 UBR5 KMT5B ATAD2B PRDM13 METTL22

1.02e-0499910115GO:0071824
DomainAnnexinVIII

ANXA8L1 ANXA8

2.78e-052992IPR009115
DomainSET

NSD1 SETDB1 KMT5B PRDM13

1.02e-0446994SM00317
DomainSET_dom

NSD1 SETDB1 KMT5B PRDM13

1.42e-0450994IPR001214
DomainSET

NSD1 SETDB1 KMT5B PRDM13

1.42e-0450994PS50280
DomainZU5

ANK2 ANK3

9.77e-049992SM00218
DomainZU5

ANK2 ANK3

1.22e-0310992PS51145
DomainSET

NSD1 SETDB1 KMT5B

1.33e-0341993PF00856
DomainZU5

ANK2 ANK3

1.77e-0312992PF00791
DomainZU5_dom

ANK2 ANK3

1.77e-0312992IPR000906
DomainANX

ANXA8L1 ANXA8

2.09e-0313992SM00335
DomainAnnexin_repeat_CS

ANXA8L1 ANXA8

2.09e-0313992IPR018252
DomainAnnexin

ANXA8L1 ANXA8

2.09e-0313992PF00191
DomainAnnexin_repeat

ANXA8L1 ANXA8

2.09e-0313992IPR018502
DomainANNEXIN

ANXA8L1 ANXA8

2.09e-0313992PS00223
Domain-

ANXA8L1 ANXA8

2.09e-03139921.10.220.10
DomainAnnexin

ANXA8L1 ANXA8

2.43e-0314992IPR001464
DomainPost-SET_dom

NSD1 SETDB1

3.18e-0316992IPR003616
DomainPostSET

NSD1 SETDB1

3.18e-0316992SM00508
DomainPOST_SET

NSD1 SETDB1

3.18e-0316992PS50868
DomainSUGAR_TRANSPORT_2

SLC2A10 SLC22A3

3.59e-0317992PS00217
DomainAcyl_Trfase/lysoPLipase

FASN PNPLA8

3.59e-0317992IPR016035
DomainZinc_finger_PHD-type_CS

NSD1 PHF21A NFX1

4.97e-0365993IPR019786
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNB ZGRF1 ICE1 RB1CC1 PHF21A KIAA1671 YEATS2 SETDB1 FASN TOX4 SALL1 BRCA2 UBR5

3.65e-104181031334709266
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FLNB FAM234B AOC1 ANK3 ARHGAP26 FRMPD1 NSD1 ALS2 ZBTB41 TACC2 RPS6KC1 TTBK2 ARID1B VCAN NFX1 OTUD4

1.26e-0710841031611544199
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ELOA2 DRP2 ARHGAP26 MUC16 NR3C1 CDY1 YEATS2 TTBK2 ARID1B SALL1 OTUD4 FGD5

4.39e-076381031231182584
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MAP1A PPM1D ZGRF1 TACC2 NR3C1 KIAA1671 YEATS2 SETDB1 SALL1 BRCA2 UBR5

1.44e-065881031138580884
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

PITPNM2 PPP2R2D TMEM94 SMG5 DMXL1 RPS6KC1 TTC7B NFX1 NAV3 OTUD4

1.56e-064751031031040226
Pubmed

Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation.

NPHS1 SALL1 SIX2

2.98e-0610103330718617
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TMEM94 FRMPD1 ALS2 ZNF365 YEATS2 SETDB1 UBR5 NAV3 OTUD4

3.59e-06407103912693553
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PITPNM2 PPP2R2D SZT2 ARHGAP26 ICE1 SMG5 ADGRV1 PHF21A ARID1B HECW2

4.06e-065291031014621295
Pubmed

Fgf8 promotes survival of nephron progenitors by regulating BAX/BAK-mediated apoptosis.

NPHS1 SALL1 SIX2

5.44e-0612103336527791
Pubmed

TaqI polymorphisms at the annexin VIII locus (ANX8).

ANXA8L1 ANXA8

8.69e-06210321364010
Pubmed

Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.

ANXA8L1 ANXA8

8.69e-062103224769558
Pubmed

Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.

ANXA8L1 ANXA8

8.69e-062103229306076
Pubmed

Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.

ANXA8L1 ANXA8

8.69e-062103221344395
Pubmed

Annexin A8 is up-regulated during mouse mammary gland involution and predicts poor survival in breast cancer.

ANXA8L1 ANXA8

8.69e-062103216203777
Pubmed

Annexins: linking Ca2+ signalling to membrane dynamics.

ANXA8L1 ANXA8

8.69e-062103215928709
Pubmed

Clinicopathological Impact of Gene Polymorphism of Nephrin and Glucocorticoid Receptor Genes in Egyptian Children with Nonfamilial Nephrotic Syndrome.

NPHS1 NR3C1

8.69e-062103235946274
Pubmed

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

ANK2 ANK3

8.69e-062103211781319
Pubmed

Structural basis of diverse membrane target recognitions by ankyrins.

ANK2 ANK3

8.69e-062103225383926
Pubmed

Annexins: from structure to function.

ANXA8L1 ANXA8

8.69e-062103211917092
Pubmed

Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.

ANXA8L1 ANXA8

8.69e-062103225803307
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ANK3 PPP2R2D PPM1D TPTE2 RB1CC1 ITPR2 KIAA1671 ARID1B TOX4 TTC7B CEBPZ OTUD4 SIX2

1.38e-0510491031327880917
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 FLNB RAP1GAP ANK2 ANK3 MAP1A PRR36 ARHGAP26 ITPR2 FASN TTC7B HECW2 VCAN OTUD4 LRRFIP1

2.08e-0514311031537142655
Pubmed

Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors.

ITPR2 SLC22A3

2.60e-053103236170823
Pubmed

Specific expression of annexin A8 in adult murine stratified epithelia.

ANXA8L1 ANXA8

2.60e-053103217082908
Pubmed

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

ANK2 ANK3

2.60e-053103215611082
Pubmed

Human ankyrins and their contribution to disease biology: An update.

ANK2 ANK3

2.60e-053103233410423
Pubmed

Sall4 Is Transiently Expressed in the Caudal Wolffian Duct and the Ureteric Bud, but Dispensable for Kidney Development.

SALL1 SIX2

2.60e-053103223825698
Pubmed

The role of CA-125, GLS and FASN in predicting cytoreduction for epithelial ovarian cancers.

MUC16 FASN

2.60e-053103232698888
Pubmed

Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.

ANK2 ANK3

2.60e-053103234289389
Pubmed

Overexpression of Sall1 in vivo leads to reduced body weight without affecting kidney development.

SALL1 SIX2

2.60e-053103220053786
Pubmed

Vascular anticoagulant beta: a novel human Ca2+/phospholipid binding protein that inhibits coagulation and phospholipase A2 activity. Its molecular cloning, expression and comparison with VAC-alpha.

ANXA8L1 ANXA8

2.60e-05310322530088
Pubmed

BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer

PPM1D RB1CC1 BRCA2

3.23e-0521103320301425
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ANK3 NSD1 KIAA1671 YEATS2 FASN ARID1B TOX4 CEBPZ LRRFIP1

3.84e-05549103938280479
Pubmed

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.

NPHS1 SALL1 SIX2

4.28e-0523103318787044
Pubmed

Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.

NR3C1 FASN GYS2

4.88e-0524103327754788
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

DDX59 ITPR2 RPS6KC1 SETDB1 ARID1B UBR5 CEBPZ ANAPC4

5.13e-05440103834244565
Pubmed

GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression.

NR3C1 KMT5B

5.19e-054103219074285
Pubmed

Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling.

SALL1 SIX2

5.19e-054103221888672
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

MAP1A TACC2 NR3C1 PHF21A YEATS2 RNF220 SALL1 BRCA2

5.47e-05444103834795231
Pubmed

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.

ANK2 ANK3

8.64e-055103225950943
Pubmed

Glial ankyrins facilitate paranodal axoglial junction assembly.

ANK2 ANK3

8.64e-055103225362471
Pubmed

The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development.

NR3C1 VCAN

8.64e-055103212495930
Pubmed

An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.

ANK2 ANK3

8.64e-055103219109891
Pubmed

Axon initial segment-associated microglia.

ANK3 VCAN

8.64e-055103225653382
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ANK2 MAP1A TACC2 ICE1 NR3C1 PHF21A KIAA1671 YEATS2 FASN TOX4 ANAPC4

1.04e-049341031133916271
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PITPNM2 SZT2 TMEM94 ARHGAP26 NSD1 ICE1 SMG5 MDFI GBA2 ITPR2 FASN NFX1

1.07e-0411051031235748872
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NSD1 MSL1 ICE1 YEATS2 ARID1B TOX4 SALL1 BRCA2 CEBPZ ATAD2B ANAPC4

1.25e-049541031136373674
Pubmed

In vivo assembly of the axon initial segment in motor neurons.

ANK2 ANK3

1.29e-046103223728480
Pubmed

SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.

NPHS1 SIX2

1.29e-046103233514561
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

PSD2 PPP2R2D BRCA2 UBR5

1.34e-0487103417148452
Pubmed

Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.

ANK2 ANK3

1.81e-04710327495297
Pubmed

A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes.

PHF21A BRCA2

1.81e-047103212032298
Pubmed

The genetic origin of mouse annexin VIII.

ANXA8L1 ANXA8

1.81e-04710329434938
Pubmed

Elongator and codon bias regulate protein levels in mammalian peripheral neurons.

BRCA2 VCAN

1.81e-047103229497044
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

MUC16 RB1CC1 YEATS2 ARID1B SALL1 UBR5 ANAPC4

1.83e-04396103726687479
Pubmed

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.

NPHS1 NR3C1 SALL1 SIX2

1.88e-0495103420843830
Pubmed

SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.

SETDB1 BRCA2

2.40e-048103230393076
Pubmed

MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.

FLNB FASN

2.40e-048103234131310
Pubmed

Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene.

BRCA2 SCG3

2.40e-04810329063750
Pubmed

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.

ANK2 MAP1A ARID1B

2.86e-0443103336950384
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

ARHGAP26 FRMPD1 ADGRV1 ITPR2 UBR5 VCAN PNPLA8

3.01e-04430103732581705
Pubmed

Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.

SALL1 SIX2

3.08e-049103224744442
Pubmed

Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.

ANK2 ANK3

3.08e-049103229867141
Pubmed

Six1 is required for the early organogenesis of mammalian kidney.

SALL1 SIX2

3.08e-049103212783782
Pubmed

Genetic Steroid-Resistant Nephrotic Syndrome Overview

NPHS1 PTPRO

3.08e-049103234436835
Pubmed

β-Catenin overexpression in the metanephric mesenchyme leads to renal dysplasia genesis via cell-autonomous and non-cell-autonomous mechanisms.

NPHS1 SIX2

3.08e-049103224637293
Pubmed

Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy.

NPHS1 P3H2

3.08e-049103235499085
Pubmed

TBR1 regulates autism risk genes in the developing neocortex.

ANK2 ARID1B

3.08e-049103227325115
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FLNB ZBTB41 ICE1 ITPR2 RPS6KC1 KIAA1671 HECW2 ATAD2B PRDM13

3.47e-04736103929676528
Pubmed

Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.

NPHS1 SALL1 SIX2

3.49e-0446103323555292
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

ANK2 ANK3

3.85e-0410103222159418
Pubmed

Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme.

SALL1 SIX2

3.85e-0410103216442091
Pubmed

Esco2 is a novel corepressor that associates with various chromatin modifying enzymes.

PHF21A SETDB1

3.85e-0410103218501190
Pubmed

A cohesin-RAD21 interactome.

FLNB PPM1D YEATS2 FASN ANAPC4

3.97e-04208103522145905
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FLNB RAP1GAP ANK2 ANK3 SMG5 ZNF365 SETDB1 RNF220 TTC7B SCG3 NAV3 LRRFIP1

4.25e-0412851031235914814
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

COL12A1 EMILIN2 VCAN

4.47e-0450103323658023
Pubmed

Strain background effects and genetic modifiers of hearing in mice.

MAP1A ADGRV1

4.69e-0411103216579977
Pubmed

Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.

NPHS1 PTPRO

4.69e-0411103211435469
Pubmed

OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis.

FASN OTUD4

4.69e-0411103236411454
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

FLNB NSD1 MSL1 YEATS2 FASN TOX4

4.76e-04332103637433992
Pubmed

Tagging genes with cassette-exchange sites.

FLNB PPP2R2D ARHGAP26 SMG5 DMXL1 RNF220

4.99e-04335103615741177
Pubmed

Calcium signaling induces partial EMT and renal fibrosis in a Wnt4mCherry knock-in mouse model.

ANK2 NAV3 SIX2

5.31e-0453103338653356
Pubmed

Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.

FLNB FASN TOX4

5.61e-0454103325631074
Pubmed

The embryonic ontogeny of the gonadal somatic cells in mice and monkeys.

SALL1 SIX2

5.62e-0412103233951437
Pubmed

Stromal prorenin receptor is critical for normal kidney development.

SALL1 SIX2

5.62e-0412103230943054
Pubmed

WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.

NPHS1 SIX2

5.62e-0412103225804736
Pubmed

Dicer function is required in the metanephric mesenchyme for early kidney development.

SALL1 SIX2

5.62e-0412103224500693
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PITPNM2 FLNB ANK2 ANK3 MAP1A ANXA8L1 ANXA8 TACC2 RPS6KC1 NAV3 LRRFIP1

5.66e-0411391031136417873
Pubmed

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.

FLNB MAP1A FASN UBR5 LRRFIP1

5.79e-04226103531452512
Pubmed

The DNA sequence and comparative analysis of human chromosome 10.

PPP2R2D WBP1L ANXA8L1 C10orf90 TACC2 ZNF365

5.82e-04345103615164054
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

FLNB USP37 SETDB1 RNF220 UBR5 NFX1 OTUD4

5.86e-04481103728190767
Pubmed

A protein interaction landscape of breast cancer.

ANK3 SMG5 KIAA1671 ARID1B TOX4 BRCA2 UBR5 ANAPC4

6.08e-04634103834591612
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PPP2R2D ANXA8L1 ANXA8 MSL1 TACC2 TTBK2 FASN ARID1B TOX4 UBR5 ANAPC4

6.35e-0411551031120360068
Pubmed

New nomenclature for chromatin-modifying enzymes.

NSD1 SETDB1 KMT5B

6.57e-0457103318022353
Pubmed

Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease.

SALL1 SIX2

6.63e-0413103238692273
Pubmed

The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo.

NPHS1 SIX2

6.63e-0413103223559562
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

FLNB FASN UBR5 VCAN OTUD4

6.90e-04235103530258100
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

YEATS2 FASN TOX4 SALL1 BRCA2 UBR5

6.95e-04357103637059091
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

FLNB DENND4A COL12A1 HSPB3 ANK2 ARID1B ZNF417

7.10e-04497103723414517
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

COL12A1 EMILIN2 ANXA8 VCAN

7.13e-04135103428675934
InteractionPHF21A interactions

FLNB ZGRF1 ICE1 RB1CC1 PHF21A KIAA1671 YEATS2 TOX4 SALL1 BRCA2 UBR5

1.09e-0634310011int:PHF21A
InteractionRCOR1 interactions

ZGRF1 ICE1 NR3C1 RB1CC1 PHF21A YEATS2 FASN TOX4 SALL1 BRCA2 UBR5 LRRFIP1

6.12e-0649410012int:RCOR1
InteractionNUP43 interactions

SZT2 NSD1 MSL1 ICE1 PHF21A YEATS2 RNF220 ARID1B BRCA2 UBR5 CEBPZ ATAD2B ANAPC4

1.30e-0562510013int:NUP43
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD1 SETDB1 KMT5B

3.32e-0434723487
GeneFamilyAnnexins|Endogenous ligands

ANXA8L1 ANXA8

1.19e-0313722404
CoexpressionONKEN_UVEAL_MELANOMA_UP

RAP1GAP ANK2 WBP1L FXYD5 MSL1 TACC2 RB1CC1 PHF21A DMXL1 ITPR2 SETDB1 FASN UBR5 LRRFIP1

2.62e-0679010314M12490
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

1.10e-0818310388e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

1.36e-081881038eb6d79d733b53f64ca615bb777c64ed456866549
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

1.60e-081921038cc9911e182a289779a2612bc213daae5607689e7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

1.60e-08192103806013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PITPNM2 ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

1.73e-08194103897534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

1.88e-0819610387e5addaa844e66f8160e05858c341866a80aed23
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK3 TACC2 ADGRV1 RNF220 FASN P3H2 SLC22A3 FHDC1

2.03e-0819810382e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

2.20e-082001038b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

2.09e-071801037198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

2.52e-071851037563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

2.91e-0718910376f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

2.91e-071891037926b5fa3064b501a57ba78583e8af33532add455
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

3.02e-07190103727a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell368C-Epithelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

3.02e-071901037459811e88d3001816c2d89034e0921c24918c17f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RAP1GAP ANK3 C10orf90 ADGRV1 RNF220 P3H2 SLC22A3

3.13e-07191103734cc997e4e5c727495f321e6807a84aa124da486
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

3.13e-071911037a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

3.13e-071911037276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

3.24e-07192103758c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RAP1GAP ANK3 C10orf90 ADGRV1 RNF220 P3H2 SLC22A3

3.24e-071921037fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

3.35e-071931037fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

3.35e-071931037738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

3.35e-071931037f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

3.85e-071971037bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.12e-0719910379a65acfe9bf500db72142469cf17bf0973540001
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.12e-071991037a38a981cffa61c8444a980916de7414e689a1b63
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3 FHDC1

4.12e-0719910372dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLNB SZT2 FXYD5 EMILIN2 VCAN FGD5 LRRFIP1

4.12e-071991037379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.26e-0720010373c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCellLung_Parenchyma-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 FHDC1

4.26e-072001037c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.26e-072001037c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB ANK3 MUC16 TACC2 ADGRV1 KIAA1671 SLC22A3

4.26e-072001037d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

4.26e-07200103765c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.26e-07200103723088edc62bf7d4db890937bfd7925dc316fcc76
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

4.26e-07200103740e969883bc302e8fbc6b6ab9814529dc1472902
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 FHDC1

4.26e-0720010373ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

4.26e-072001037ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

4.26e-072001037acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.26e-072001037b2d61bc3afac0d78aa30082760da5b1a15d1fad2
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

4.26e-072001037ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.26e-07200103735c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellParenchyma_Control_(B.)-Epithelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 FHDC1

4.26e-0720010379970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RAP1GAP ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

4.26e-072001037eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP ANK3 TACC2 ADGRV1 FASN FHDC1

4.44e-0618410360ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

4.44e-061841036369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP ANK3 TACC2 ADGRV1 FASN FHDC1

4.44e-0618410362a8338e94937686a148b5433515700ca0f674058
ToppCellIPF-Epithelial-ATII|World / Disease state, Lineage and Cell class

ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.72e-0618610366a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

4.72e-061861036f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RAP1GAP ANK3 TACC2 ADGRV1 P3H2 SLC22A3

4.87e-0618710365df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

RAP1GAP ANK3 FASN P3H2 SLC22A3 FHDC1

4.87e-061871036030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

ANK3 TACC2 ADGRV1 FASN P3H2 SLC22A3

5.02e-061881036c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

RAP1GAP ANK2 PRR36 MUC16 TACC2 P3H2

5.02e-061881036a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

ANK3 TACC2 ADGRV1 P3H2 SLC22A3 FHDC1

5.17e-061891036dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK2 MAP1A CDHR3 ITPR2 NAV3 KIAA2012

5.17e-061891036cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

FLNB ARHGAP26 ITPR2 KIAA1671 VCAN FGD5

5.17e-06189103675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

ANK3 TACC2 FASN P3H2 SLC22A3 FHDC1

5.33e-061901036d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

5.50e-0619110366cb2c107bc674aa173b4009f320a1687a76f3979
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

5.83e-0619310368646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCellnormal_Lung-Epithelial_cells-AT2|normal_Lung / Location, Cell class and cell subclass

RAP1GAP ANK3 FASN P3H2 SLC22A3 FHDC1

5.83e-06193103680ad1bdc50ecb8a50362f718248441cae20904a6
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PHF21A KIAA1671 HECW2 NAV3 FGD5

5.83e-061931036e1d546165dcc2392f540162206852c4717d7306f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.19e-0619510366617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.19e-0619510366867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.19e-061951036fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.19e-0619510363e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.19e-061951036955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.19e-06195103637aa6e4123d37de4de42ca68d3020f2a7686ce02
ToppCell3'-Parenchyma_lung-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.19e-061951036eec187c087e432417bc346c5d3ead72f58bf3215
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.37e-06196103682b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCellcellseq-Epithelial-Epithelial_Alveolar|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RAP1GAP TACC2 FASN P3H2 SLC22A3 FHDC1

6.37e-061961036a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCellmedial-2-Epithelial-Alveolar_Epithelial_Type_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAP1GAP ANK3 FASN P3H2 SLC22A3 FHDC1

6.75e-061981036102a4cbb138adbfba11ed955420095daa098532f
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TACC2 ADGRV1 RNF220 P3H2 SLC22A3 FHDC1

6.75e-061981036f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_2-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAP1GAP ANK3 FASN P3H2 SLC22A3 FHDC1

6.75e-0619810367caeed2d5dc78866023c8f38edcec9886baa9f2c
ToppCellASK428-Epithelial-Type_2|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

RAP1GAP ANK3 FASN P3H2 SLC22A3 FHDC1

6.75e-061981036ec0d1801363adb70c6a26655b79d12b438c7417d
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAP1GAP ANK3 FASN P3H2 SLC22A3 FHDC1

6.75e-06198103653e5d76831d70b9a476f3ef3a81e13eda974d543
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 ANK2 MDFI P3H2 SLC22A3 VCAN

6.95e-0619910369b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 ANK2 MDFI P3H2 SLC22A3 VCAN

6.95e-061991036251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT2|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3

6.95e-061991036fa5ddba3ac1ebe712cd4cdc3f20339f7c715d039
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 ANK2 MDFI P3H2 SLC22A3 VCAN

6.95e-061991036117f4f43b6c06dda553799b1063e827bce697370
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RAP1GAP ANK3 ADGRV1 FASN P3H2 SLC22A3

7.15e-062001036e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3

7.15e-062001036cf1991853e10c562edae9a0d71a209f35b07db80
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAP1GAP ANK3 FASN P3H2 SLC22A3 FHDC1

7.15e-062001036bcaab6cb7f165dfcf3fb499497b361b062f9dbff
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3

7.15e-0620010367618ae284625c5c121bcc00eb9f07e5b1e3adf23
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RAP1GAP ANK3 TACC2 FASN P3H2 SLC22A3

7.15e-06200103623b319bf7e5ae03e5baa777c951da9bfc97cca8c
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP26 FXYD5 EMILIN2 VCAN PRDM13

2.94e-0515410351e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FXYD5 EMILIN2 SAMSN1 SLC22A3 KIAA2012

3.03e-051551035c648512305166d2a2f0e284c127bc802af908071
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

PITPNM2 ANK3 TACC2 ADGRV1 SLC22A3

3.23e-05157103531d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

PITPNM2 ANK3 TACC2 ADGRV1 SLC22A3

3.86e-051631035e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP ANK3 TACC2 FASN FHDC1

3.97e-051641035b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP ANK3 TACC2 FASN FHDC1

3.97e-0516410353aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP HSPB3 PTPRO VCAN METTL22

3.97e-0516410350853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCelldroplet-Fat-Scat-18m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP26 EMILIN2 SAMSN1 PTPRO VCAN

4.09e-051651035015f8f408d7fd17292defe63fa02b16eed642dfb
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FXYD5 EMILIN2 SAMSN1 PTPRO VCAN

4.33e-0516710358aacb102c1b0067a86eb6c2acedd07667198487d
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FXYD5 EMILIN2 SAMSN1 PTPRO VCAN

4.71e-051701035a6f2a792980e6a1025b8f1b0eda442a555938488
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

FLNB COL12A1 ANK3 TACC2 ADGRV1

4.71e-051701035e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 SALL1 SLC22A3 VCAN FGD5

4.85e-051711035a5634b76476b8b2488a706bbab5141f7bd94631f
ToppCellBronchial_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ANK2 ITPR2 SALL1 P3H2 NAV3

5.12e-051731035e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP TACC2 SLC2A10 SLC22A3 FHDC1

5.12e-051731035ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCellBronchial_Brush-Epithelial-Ionocytes|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ANK2 ITPR2 SALL1 P3H2 NAV3

5.12e-051731035f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 SALL1 SLC22A3 VCAN FGD5

5.41e-051751035e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

COL12A1 MAP1A HECW2 VCAN KIAA2012

5.86e-051781035ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 ADGRV1 RNF220 P3H2 SLC22A3

6.02e-051791035fd2cbee532e7b44113410dca82aec7db1a7fb69f
DiseaseMalignant neoplasm of breast

FLNB RAP1GAP DDX59 ANK2 PPM1D FRMPD1 TACC2 RB1CC1 ZNF365 SLC2A10 FASN ARID1B BRCA2 P3H2 FGD5 LRRFIP1

6.48e-07107410016C0006142
Diseasesitting height ratio

NSD1 C10orf90 ARID1B ATAD2B

2.75e-05511004EFO_0007118
DiseaseBREAST CANCER

PPM1D RB1CC1 BRCA2

4.81e-05211003114480
DiseaseMalignant tumor of breast

PPM1D RB1CC1 BRCA2

1.04e-04271003cv:C0006142
DiseaseBreast neoplasm

PPM1D RB1CC1 BRCA2

1.04e-04271003cv:C1458155
DiseaseFamilial cancer of breast

PPM1D RB1CC1 BRCA2

1.04e-04271003cv:C0346153
Diseasehematocrit

AOC1 ARHGAP26 WBP1L ADGRV1 NR3C1 USP37 ITPR2 TTBK2 ARID1B SALL1 GYS2 FGD5

1.61e-04101110012EFO_0004348
DiseaseC-reactive protein measurement

RAP1GAP ANK3 MAP1A PPP2R2D CDHR3 PHF21A YEATS2 SALL1 SCG3 GYS2 RP1L1 KIAA2012 ANAPC4

2.19e-04120610013EFO_0004458
DiseaseNeurodevelopmental Disorders

ANK2 PPM1D ARID1B KMT5B

2.88e-04931004C1535926
Diseasetestosterone measurement

DENND4A AOC1 ANK2 ANK3 MAP1A ARHGAP26 WBP1L NR3C1 FASN ARID1B P3H2 SLC22A3 ANAPC4

3.73e-04127510013EFO_0004908
DiseaseBreast Carcinoma

PPM1D RB1CC1 ZNF365 SLC2A10 FASN ARID1B BRCA2 FGD5

4.97e-045381008C0678222
Diseaseneuroblastoma (is_implicated_in)

NSD1 ARID1B

5.03e-04101002DOID:769 (is_implicated_in)
Diseaserenal Wilms' tumor (is_implicated_in)

SALL1 SIX2

5.03e-04101002DOID:5176 (is_implicated_in)
Diseasesuicide

FXYD5 RPS6KC1 RP1L1

6.59e-04501003EFO_0007624
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2D ITPR2

7.34e-04121002DOID:1441 (implicated_via_orthology)
Diseaserevision of total hip arthroplasty

ICE1 RXFP3

1.01e-03141002EFO_0020973
Diseasemean corpuscular hemoglobin concentration

DENND4A SMG5 DMXL1 ITPR2 TTBK2 UBR5 HECW2 ATAD2B RP1L1 OTUD4 KIAA2012

1.31e-03110510011EFO_0004528
Diseasesexual dimorphism measurement

PITPNM2 AOC1 ARHGAP26 WBP1L NSD1 MSL1 NR3C1 PHF21A SETDB1 ATAD2B OTUD4

1.32e-03110610011EFO_0021796
Diseasemelanoma

RAP1GAP SETDB1 FASN BRCA2 PTPRO

1.59e-032481005C0025202
Diseaseresponse to ketamine

ARHGAP26 NR3C1 KIAA1671

1.68e-03691003EFO_0009748
Diseasebreast cancer (is_implicated_in)

PPM1D RB1CC1 BRCA2 UBR5

1.72e-031501004DOID:1612 (is_implicated_in)
DiseaseMalignant Glioma

PPM1D DMXL1 BRCA2

1.75e-03701003C0555198
Diseasemixed gliomas

PPM1D DMXL1 BRCA2

1.75e-03701003C0259783
Diseasegamma-aminoisobutyric acid measurement

AOC1 TACC2

1.87e-03191002EFO_0010482
Diseasechronic kidney disease (is_marker_for)

SALL1 SIX2

2.08e-03201002DOID:784 (is_marker_for)
DiseaseMammary Carcinoma, Human

PPM1D RB1CC1 ZNF365 SLC2A10 FASN BRCA2 FGD5

2.09e-035251007C4704874
DiseaseMammary Neoplasms, Human

PPM1D RB1CC1 ZNF365 SLC2A10 FASN BRCA2 FGD5

2.09e-035251007C1257931
DiseaseMammary Neoplasms

PPM1D RB1CC1 ZNF365 SLC2A10 FASN BRCA2 FGD5

2.14e-035271007C1458155
Diseasecystatin C measurement

PPM1D NSD1 ADGRV1 USP37 SALL1 KIAA2012

2.50e-034021006EFO_0004617
Diseaselymphocyte count, response to vaccine

ARHGAP26 HECW2

2.51e-03221002EFO_0004587, EFO_0004645
DiseaseRenal glomerular disease

NPHS1 SALL1

2.75e-03231002C0268731
DiseaseGlomerulopathy Assessment

NPHS1 SALL1

2.75e-03231002C4521256
DiseaseAnhedonia

ANK3 SETDB1

2.99e-03241002C0178417
DiseaseGlioma

PPM1D DMXL1 BRCA2

3.26e-03871003C0017638

Protein segments in the cluster

PeptideGeneStartEntry
TLAPDSPFDHKTVSG

CDY1

141

Q9Y6F8
EKPESLHSFSVEAPV

ANAPC4

96

Q9UJX5
HTEPVSLFPEESSGE

VCAN

1536

P13611
SVREDSEHGEKPVPS

ALS2

356

Q96Q42
SEEVTGQFSVHPETP

CEACAM8

131

P31997
FHVELTSPPTTEGFK

GYS2

621

P54840
HGTPAVSEKPDVATV

ADGRV1

5196

Q8WXG9
HSKFFEEPEDPSSRS

PPP2R2D

271

Q66LE6
VHDPFSDVSDSSFPK

ARID1B

1306

Q8NFD5
KGHDSTEEPPLFSSH

AOC1

271

P19801
TDGPLVTDPETHKST

FXYD5

81

Q96DB9
PETHIFTAPEEGSSQ

DMRTC1;

31

Q5HYR2
SHDSPVKAVAVDPTE

DMXL1

2926

Q9Y485
DESFKSEHTVFVTPP

DENND4A

666

Q7Z401
QDSTPESRHGAVKSP

NSD1

211

Q96L73
HSLPEASVSSKPDEG

OTUD4

921

Q01804
HPSKQGSPTEHEDVT

ITPR2

951

Q14571
KGIPVDDTDRHSPSS

PLA2G2C

51

Q5R387
YKHEGLAETPETSPE

ANK2

2231

Q01484
EGVTVKSSSHFNPDP

ANXA8

11

P13928
PVSEDSAADGTPKHS

HECW2

371

Q9P2P5
TSFPKSVEHVSPDTA

RB1CC1

256

Q8TDY2
ESSTGSPEEPNKFHS

FHDC1

556

Q9C0D6
EPDSAGHTKISTSIP

MUC16

711

Q8WXI7
PDTEVTTISHFPEKT

MUC16

2256

Q8WXI7
PDHDKSTVPPDTFTG

MUC16

5236

Q8WXI7
EHPTPLTKVAAAGDS

NPHS1

841

O60500
ADSAGPKTVPSHVFS

ELOA2

446

Q8IYF1
SPDEHILTPDSSFSK

MAP1A

1311

P78559
TSQVTPAEEKDGHSP

MAP1A

2651

P78559
PTEPKDTDTLVHEAG

KIAA1671

1521

Q9BY89
VDTHVDPPFHKSSDG

MDP1

21

Q86V88
GVEDIKSHPFFTPVD

RPS6KC1

1046

Q96S38
PAGTDETATHKDLIP

SLC2A10

186

O95528
VDGSLSDSHVSPPAK

ATAD2B

76

Q9ULI0
IEESTPVHDSPGKDD

KMT5B

626

Q4FZB7
AKDSHPSEEPVKSFS

DDX59

81

Q5T1V6
VDSAAETPPREGKSH

HSPB3

56

Q12988
VSTKFADEHVPGSPF

FLNB

2071

O75369
ADEHVPGSPFTVKIS

FLNB

2076

O75369
TTSKHIPQTDTEGDP

NAV3

2331

Q8IVL0
KPHLSEVTTEGYPSE

FAM234B

71

A2RU67
PEKEEGSSEVGPIFH

FGD5

1416

Q6ZNL6
SHPDSPENEKTETTF

PHF21A

451

Q96BD5
EDAGPESTKPVGVFH

NFX1

201

Q12986
ESTKPVGVFHPDSSE

NFX1

206

Q12986
PESQKGVDSPRTSDH

KIAA2012

551

Q0VF49
PTEKEFPKTHSDVSS

NR3C1

151

P04150
GEFVVSPEPDTSVHT

PPM1D

286

O15297
KTSPHTPNEKFEGAT

P3H2

496

Q8IVL5
VKHEAVSDQTSGEPP

PITPNM2

271

Q9BZ72
GPSTHPKEKAFSSEI

MSL1

406

Q68DK7
HFTEETPEIPSGNIS

PTPRO

266

Q16827
SPDHPVVKSEFESSP

BTBD18

436

B2RXH4
SAEKSPEASHTGPAF

ICE1

1466

Q9Y2F5
EGVTVKSSSHFNPDP

ANXA8L1

11

Q5VT79
TPKHISESLGAEVDP

BRCA2

176

P51587
TVSVSAVHDEGESPP

COL12A1

1631

Q99715
PHGVPDKSSVQSDEV

GBA2

806

Q9HCG7
PEDRKSSTPGSLHEE

CACNA1S

1751

Q13698
VAENSPPGTSVHKFS

CDHR3

31

Q6ZTQ4
PKEPTIEHGDSSFSL

FRMPD1

1001

Q5SYB0
PGKESPSSDVFDHSP

ANK3

3056

Q12955
EVVTGSTHPAEAAPE

MDFI

36

Q99750
GEKAPEPISTQSHSV

MASP1

261

P48740
QHPKPDTTVSGDTET

EMILIN2

231

Q9BXX0
EDKPEEPTAHAFVST

FASN

1521

P49327
GPETHPKSIDIFDFT

BMP2KL

171

Q5H9B9
IPTTATPTHDEKGEE

PRDM13

121

Q9H4Q3
PETVDDVEKLGSPHS

SLC22A3

526

O75751
GFVHVSPQDSKDTPT

SALL1

1091

Q9NSC2
EPHSDENGSTTPKVK

CEBPZ

146

Q03701
SHPREKGQTTPDTEA

DRP2

901

Q13474
HKPTVSAFFTGPEEL

KBTBD6

26

Q86V97
AAEPKEVPAHSTEVG

LRRFIP1

481

Q32MZ4
PSVSHKPFESIDEGQ

HGD

66

Q93099
YKPGSESVHTVDKPT

PNPLA8

256

Q9NP80
RPFTATTKPEHEDQG

RXFP3

416

Q9NSD7
VPEHFTLPDSTKSGV

SZT2

516

Q5T011
PTGESSEPEAKVLHT

SMG5

6

Q9UPR3
SKPDDSTEAHEGDPT

SAMSN1

36

Q9NSI8
PTEGPRKSVSSASEH

PRR36

201

Q9H6K5
PEEAVHEDSSTPFRK

ARHGAP26

746

Q9UNA1
KTPDSGHVSQEPKSE

RAP1GAP

521

P47736
IKREGESPTASPHSS

RNF220

276

Q5VTB9
DVHTKEPPSAETGST

METTL22

71

Q9BUU2
IKSTVCGPESFTPDH

SARDH

376

Q9UL12
ENGLSETTSKDSHPP

SETDB1

936

Q15047
HADDKETSFSPDTPL

C10orf90

226

Q96M02
PGLPTSDTKASFEAH

ZNF365

146

Q70YC5
AEVAPGKTHTDPTST

RP1L1

1706

Q8IWN7
TVLFFSGKVEPPHSS

TMEM94

431

Q12767
DTEEPTKDPDVAFHG

PSD2

56

Q9BQI7
AVEKTDSETMHGPPF

ZNF587

191

Q96SQ5
PFHSELTEKSSPEET

ZBTB41

181

Q5SVQ8
GHKTTGSPSDEEPEV

TTBK2

571

Q6IQ55
AVEKTDSETMHGPPF

ZNF417

191

Q8TAU3
PSHSFSAVFDEDKPI

TACC2

2016

O95359
SSEDEKTPSGTPDHS

SIX2

211

Q9NPC8
HEDDDKPTSSPDTGF

USP37

726

Q86T82
TLPDFSDPETGSVHA

TTC7B

646

Q86TV6
GEHLPFLTSVSDKPT

ZGRF1

586

Q86YA3
KGTTEEAPAKESPHT

TPTE2

11

Q6XPS3
EAPAKESPHTSEFKG

TPTE2

16

Q6XPS3
DHITFVAETGPKPSE

TGM7

56

Q96PF1
DSSEHGAPDSKEKTP

WBP1L

226

Q9NX94
PAPSEKSHEETDSTK

SCG3

356

Q8WXD2
TFHTPSLGDEEFEIP

TOX4

26

O94842
QSHEPVPDTSVEKGF

YEATS2

371

Q9ULM3
ETESSKPGPSAHDLA

UBR5

2131

O95071