Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

6.65e-062522GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

6.65e-062522GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

1.99e-053522GO:0043993
GeneOntologyMolecularFunctionATP-dependent activity

DDX19B DDX19A KATNAL2 MYH6 ABCA2 MYO9A RFC1 DHX9

1.74e-04614528GO:0140657
GeneOntologyMolecularFunctioncomplement component C1q complex binding

C4A C4B

2.95e-0410522GO:0001849
GeneOntologyMolecularFunctiontranscription coactivator binding

FLYWCH1 CREBBP EP300

3.76e-0454523GO:0001223
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

6.83e-0415522GO:0010484
GeneOntologyMolecularFunctionchromatin DNA binding

H2AL3 CREBBP EP300 DHX9

9.35e-04167524GO:0031490
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX19B DDX19A KATNAL2 ABCA2 RFC1 DHX9

9.67e-04441526GO:0016887
GeneOntologyMolecularFunctionRNA helicase activity

DDX19B DDX19A DHX9

1.10e-0378523GO:0003724
GeneOntologyMolecularFunctiontranscription coactivator activity

MTA3 CREBBP JMY EP300 DHX9

1.13e-03303525GO:0003713
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DDX19B DDX19A DHX9

1.19e-0380523GO:0008186
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

1.35e-0321522GO:0042975
GeneOntologyMolecularFunctionendopeptidase regulator activity

ABCA2 C3 C4A C4B

1.85e-03201524GO:0061135
GeneOntologyMolecularFunctionopsonin binding

C4A C4B

1.92e-0325522GO:0001846
GeneOntologyMolecularFunctioncomplement binding

C4A C4B

3.14e-0332522GO:0001848
GeneOntologyMolecularFunctiontranscription coregulator activity

MTA3 FLYWCH1 CREBBP JMY EP300 DHX9

3.29e-03562526GO:0003712
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP EP300

4.18e-0337522GO:0043425
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH6 MYO9A

4.40e-0338522GO:0000146
GeneOntologyMolecularFunctionpeptidase regulator activity

ABCA2 C3 C4A C4B

4.47e-03257524GO:0061134
GeneOntologyMolecularFunctiontranscription coregulator binding

FLYWCH1 CREBBP EP300

5.80e-03140523GO:0001221
GeneOntologyBiologicalProcesspositive regulation of apoptotic cell clearance

C3 C4A C4B

8.89e-078533GO:2000427
GeneOntologyBiologicalProcessregulation of apoptotic cell clearance

C3 C4A C4B

1.90e-0610533GO:2000425
GeneOntologyBiologicalProcesspoly(A)+ mRNA export from nucleus

DDX19B DDX19A IWS1

3.54e-0525533GO:0016973
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

3.87e-054532GO:0018076
GeneOntologyBiologicalProcessN-terminal protein amino acid modification

CREBBP EP300 HHATL

5.58e-0529533GO:0031365
GeneOntologyBiologicalProcesspositive regulation of cellular response to transforming growth factor beta stimulus

CDKN2B CREBBP EP300

9.89e-0535533GO:1903846
GeneOntologyBiologicalProcesspositive regulation of transforming growth factor beta receptor signaling pathway

CDKN2B CREBBP EP300

9.89e-0535533GO:0030511
GeneOntologyBiologicalProcessRNA export from nucleus

DDX19B DDX19A DHX9 IWS1

1.08e-0496534GO:0006405
GeneOntologyBiologicalProcesspositive regulation of phagocytosis

C3 C4A C4B TUB

1.22e-0499534GO:0050766
GeneOntologyBiologicalProcessface morphogenesis

ANKRD11 CREBBP EP300

1.59e-0441533GO:0060325
GeneOntologyBiologicalProcessprotein acylation

ANKRD11 CREBBP EP300 HHATL

1.71e-04108534GO:0043543
GeneOntologyBiologicalProcesscomplement activation, classical pathway

C3 C4A C4B

1.97e-0444533GO:0006958
GeneOntologyBiologicalProcessapoptotic cell clearance

C3 C4A C4B

2.55e-0448533GO:0043277
GeneOntologyBiologicalProcesshead morphogenesis

ANKRD11 CREBBP EP300

2.55e-0448533GO:0060323
GeneOntologyBiologicalProcessregulation of phagocytosis

C3 C4A C4B TUB

4.12e-04136534GO:0050764
GeneOntologyCellularComponentsymbiont cell surface

C4A C4B

1.75e-048532GO:0106139
GeneOntologyCellularComponentother organism part

C4A C4B

2.24e-049532GO:0044217
HumanPhenoAbnormality of the incisor

STAG1 ANKRD11 ARHGAP29 WNT10A CREBBP EP300

1.71e-06108196HP:0000676
HumanPhenoAbnormal number of permanent teeth

ARHGAP29 WNT10A CREBBP EP300

6.73e-0635194HP:0011044
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

1.32e-052192HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

1.32e-052192HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

1.32e-052192HP:0001042
HumanPhenoSkin appendage neoplasm

WNT10A CREBBP EP300

3.47e-0518193HP:0012842
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

3.95e-053192HP:0008752
HumanPhenoPhobia

CREBBP EP300

3.95e-053192HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

3.95e-053192HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

3.95e-053192HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

3.95e-053192HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

3.95e-053192HP:0005895
HumanPhenoAbnormal incisor morphology

ARHGAP29 WNT10A CREBBP EP300

6.73e-0562194HP:0011063
HumanPhenoAgenesis of permanent teeth

WNT10A CREBBP EP300

7.43e-0523193HP:0006349
HumanPhenoTrichiasis

CREBBP EP300

7.87e-054192HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

7.87e-054192HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

7.87e-054192HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

7.87e-054192HP:0006200
HumanPhenoVascular ring

CREBBP EP300

7.87e-054192HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

7.87e-054192HP:0031207
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

1.31e-045192HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

1.31e-045192HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

1.31e-045192HP:0030421
HumanPhenoAbnormal epididymis morphology

C4A CREBBP EP300

1.68e-0430193HP:0009714
HumanPhenoLarge foramen magnum

CREBBP EP300

1.96e-046192HP:0002700
HumanPhenoDeviated nasal septum

CREBBP EP300

2.74e-047192HP:0004411
HumanPhenoPilomatrixoma

CREBBP EP300

4.67e-049192HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

4.67e-049192HP:0002341
HumanPhenoDecreased circulating complement C3 concentration

C3 C4A C4B

4.94e-0443193HP:0005421
HumanPhenoMeningioma

CDKN2B CREBBP EP300

5.29e-0444193HP:0002858
HumanPhenoWidely-spaced maxillary central incisors

STAG1 ANKRD11

5.83e-0410192HP:0001566
HumanPhenoFrontal hirsutism

CREBBP EP300

5.83e-0410192HP:0011335
HumanPhenoProminent fingertip pads

CREBBP EP300 NR2F1

6.04e-0446193HP:0001212
HumanPhenoPneumonia

MYH6 PKHD1 C3 C4B CREBBP EP300

6.79e-04311196HP:0002090
HumanPhenoChiari type I malformation

STAG1 CREBBP EP300

6.85e-0448193HP:0007099
HumanPhenoProminent digit pad

CREBBP EP300 NR2F1

6.85e-0448193HP:0011298
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

7.11e-0411192HP:0031251
HumanPhenoCongenital malformation of the left heart

ANKRD11 CREBBP EP300

8.18e-0451193HP:0045017
HumanPhenoDuodenal ulcer

CDKN2B EP300

8.51e-0412192HP:0002588
HumanPhenoAnorexia

CDKN2B PKHD1 C4A C4B

9.76e-04124194HP:0002039
HumanPhenoFacial grimacing

CREBBP EP300

1.00e-0313192HP:0000273
HumanPhenoCentral incisor gap

STAG1 ANKRD11

1.00e-0313192HP:0001570
HumanPhenoKeloids

CREBBP EP300

1.00e-0313192HP:0010562
HumanPhenoWidely-spaced incisors

STAG1 ANKRD11

1.00e-0313192HP:0006304
HumanPhenoLow weight

CDKN2B STAG1 PKHD1 C4A C4B CREBBP EP300 B4GALT1

1.10e-03627198HP:0001823
HumanPhenoDuplication of phalanx of hallux

CREBBP EP300

1.17e-0314192HP:0010066
HumanPhenoHypoplastic aortic arch

CREBBP EP300

1.17e-0314192HP:0012304
HumanPhenoParietal foramina

CREBBP EP300

1.17e-0314192HP:0002697
HumanPhenoAbnormal spaced incisors

STAG1 ANKRD11

1.17e-0314192HP:0040159
HumanPhenoReduced circulating complement concentration

C3 C4A C4B

1.19e-0358193HP:0004431
MousePhenoabnormal renal glomerulus morphology

STAG1 MYO9A PKHD1 C3 C4A C4B B4GALT1

1.67e-05264447MP:0005325
MousePhenodecreased vascular permeability

C3 C4A C4B

2.30e-0518443MP:0003071
MousePhenoabnormal renal corpuscle morphology

STAG1 MYO9A PKHD1 C3 C4A C4B B4GALT1

3.26e-05293447MP:0002827
MousePhenodecreased spleen germinal center size

C3 C4A C4B

4.30e-0522443MP:0008484
MousePhenoabnormal kidney cortex morphology

STAG1 MYO9A PKHD1 C3 C4A C4B B4GALT1

6.17e-05324447MP:0000521
MousePhenodecreased spleen germinal center number

C3 C4A C4B

7.19e-0526443MP:0008482
MousePhenodecreased susceptibility to Coronaviridae infection

C3 C4A C4B

9.02e-0528443MP:0020950
MousePhenoabnormal fear/anxiety-related behavior

URB1 ABCA2 TRPC4AP PTPRA AJAP1 C3 C4A C4B CREBBP NR2F1 HHATL

9.60e-059194411MP:0002065
MousePhenocortical renal glomerulopathies

MYO9A C3 C4A C4B B4GALT1

1.24e-04156445MP:0000523
MousePhenoglomerulonephritis

C3 C4A C4B B4GALT1

2.21e-0495444MP:0002743
MousePhenodecreased hair follicle number

STAG1 PNN B4GALT1

2.85e-0441443MP:0000379
MousePhenoabnormal digestive system morphology

KATNAL2 PNN PKHD1 ARHGAP29 WNT10A C3 C4A C4B CREBBP EP300 CNR2 B4GALT1

3.08e-0412334412MP:0000462
MousePhenoabnormal nephron morphology

STAG1 MYO9A PKHD1 C3 C4A C4B B4GALT1

3.36e-04426447MP:0003881
DomainAnaphylatoxin_comp_syst

C3 C4A C4B

2.03e-075523IPR018081
DomainAnaphylatoxn_comp_syst_dom

C3 C4A C4B

2.03e-075523IPR001840
DomainANATO

C3 C4A C4B

7.07e-077523SM00104
DomainANATO

C3 C4A C4B

7.07e-077523PF01821
DomainANAPHYLATOXIN_2

C3 C4A C4B

7.07e-077523PS01178
DomainANAPHYLATOXIN_1

C3 C4A C4B

7.07e-077523PS01177
DomainAnaphylatoxin/fibulin

C3 C4A C4B

7.07e-077523IPR000020
DomainThiol-ester_cl

C3 C4A C4B

1.13e-068523PF10569
DomainMacrogloblnA2_thiol-ester-bond

C3 C4A C4B

1.13e-068523IPR019565
DomainMacrogloblnA2_CS

C3 C4A C4B

1.13e-068523IPR019742
DomainA2M_N

C3 C4A C4B

2.41e-0610523PF01835
DomainA2M_N

C3 C4A C4B

2.41e-0610523IPR002890
DomainA-macroglobulin_rcpt-bd

C3 C4A C4B

2.41e-0610523IPR009048
DomainALPHA_2_MACROGLOBULIN

C3 C4A C4B

2.41e-0610523PS00477
DomainA2M

C3 C4A C4B

2.41e-0610523PF00207
DomainA2M_N_2

C3 C4A C4B

2.41e-0610523IPR011625
DomainA2M_comp

C3 C4A C4B

2.41e-0610523IPR011626
DomainA2M_N_2

C3 C4A C4B

2.41e-0610523PF07703
DomainA2M_recep

C3 C4A C4B

2.41e-0610523PF07677
DomainA2M_comp

C3 C4A C4B

2.41e-0610523PF07678
DomainMacroglobln_a2

C3 C4A C4B

2.41e-0610523IPR001599
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

7.60e-062522IPR014744
DomainHAT_KAT11

CREBBP EP300

7.60e-062522PF08214
DomainKIX

CREBBP EP300

7.60e-062522PS50952
DomainZnF_TAZ

CREBBP EP300

7.60e-062522SM00551
DomainCBP_P300_HAT

CREBBP EP300

7.60e-062522IPR031162
DomainDUF902

CREBBP EP300

7.60e-062522PF06001
Domain-

CREBBP EP300

7.60e-0625221.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

7.60e-062522IPR010303
Domain-

CREBBP EP300

7.60e-0625221.10.1630.10
DomainCreb_binding

CREBBP EP300

7.60e-062522PF09030
Domain-

CREBBP EP300

7.60e-0625221.10.246.20
Domainzf-TAZ

CREBBP EP300

7.60e-062522PF02135
DomainZF_TAZ

CREBBP EP300

7.60e-062522PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

7.60e-062522IPR013178
DomainKAT11

CREBBP EP300

7.60e-062522SM01250
DomainZnf_TAZ

CREBBP EP300

7.60e-062522IPR000197
DomainKIX_dom

CREBBP EP300

7.60e-062522IPR003101
DomainKIX

CREBBP EP300

7.60e-062522PF02172
DomainCBP_P300_HAT

CREBBP EP300

7.60e-062522PS51727
DomainC345C

C3 C4A C4B

1.35e-0517523SM00643
DomainTerpenoid_cyclase/PrenylTrfase

C3 C4A C4B

1.61e-0518523IPR008930
DomainNTR

C3 C4A C4B

1.91e-0519523PF01759
DomainNetrin_module_non-TIMP

C3 C4A C4B

1.91e-0519523IPR018933
DomainNTR

C3 C4A C4B

3.47e-0523523PS50189
DomainNetrin_domain

C3 C4A C4B

3.47e-0523523IPR001134
Domain-

C3 C4A

4.55e-0545221.20.91.20
DomainTIMP-like_OB-fold

C3 C4A C4B

5.06e-0526523IPR008993
DomainP-loop_NTPase

DDX19B DDX19A KATNAL2 MYH6 ABCA2 MYO15B MYO9A RFC1 UST DHX9

9.85e-058485210IPR027417
DomainNuc_rcpt_coact

CREBBP EP300

1.13e-046522IPR009110
DomainMyosin_head_motor_dom

MYH6 MYO15B MYO9A

1.60e-0438523IPR001609
DomainMYOSIN_MOTOR

MYH6 MYO15B MYO9A

1.60e-0438523PS51456
DomainMyosin_head

MYH6 MYO15B MYO9A

1.60e-0438523PF00063
DomainMYSc

MYH6 MYO15B MYO9A

1.60e-0438523SM00242
DomainA2M_N_2

C3 C4A

2.11e-048522SM01359
Domain-

C3 C4A

2.11e-0485222.60.40.690
DomainA2M_recep

C3 C4A

2.11e-048522SM01361
DomainA2M

C3 C4A

2.11e-048522SM01360
Domain-

C3 C4A

4.93e-04125221.50.10.20
DomainDEAD/DEAH_box_helicase_dom

DDX19B DDX19A DHX9

1.10e-0373523IPR011545
DomainDEAD

DDX19B DDX19A DHX9

1.10e-0373523PF00270
DomainZZ

CREBBP EP300

1.13e-0318522PF00569
DomainZF_ZZ_2

CREBBP EP300

1.13e-0318522PS50135
DomainZF_ZZ_1

CREBBP EP300

1.13e-0318522PS01357
DomainZnf_ZZ

CREBBP EP300

1.26e-0319522IPR000433
DomainZnF_ZZ

CREBBP EP300

1.26e-0319522SM00291
DomainIQ_motif_EF-hand-BS

MYH6 MYO15B MYO9A

2.02e-0390523IPR000048
DomainIQ

MYH6 MYO15B MYO9A

2.21e-0393523PS50096
DomainBromodomain_CS

CREBBP EP300

2.37e-0326522IPR018359
DomainHelicase_C

DDX19B DDX19A DHX9

3.30e-03107523PF00271
PathwayREACTOME_ACTIVATION_OF_C3_AND_C5

C3 C4A C4B

9.17e-077433MM14685
PathwayREACTOME_ACTIVATION_OF_C3_AND_C5

C3 C4A C4B

1.46e-068433M27031
PathwayBIOCARTA_LECTIN_PATHWAY

C3 C4A C4B

4.29e-0611433MM1430
PathwayBIOCARTA_CLASSIC_PATHWAY

C3 C4A C4B

5.71e-0612433MM1368
PathwayBIOCARTA_LECTIN_PATHWAY

C3 C4A C4B

7.40e-0613433M4732
PathwayBIOCARTA_CLASSIC_PATHWAY

C3 C4A C4B

1.17e-0515433M7146
PathwayWP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY

C3 C4A C4B

1.74e-0517433MM15944
PathwayBIOCARTA_COMP_PATHWAY

C3 C4A C4B

1.74e-0517433MM1369
PathwayBIOCARTA_COMP_PATHWAY

C3 C4A C4B

2.91e-0520433M917
PathwayWP_COMPLEMENT_ACTIVATION

C3 C4A C4B

3.91e-0522433M39502
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

9.04e-055432MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

9.04e-055432M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

9.04e-055432M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

9.04e-055432M27228
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.35e-046432M22062
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.89e-047432MM1573
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

2.52e-048432M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

2.52e-048432M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

2.52e-048432M48024
PathwayKEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

C4A C4B

2.52e-048432M47872
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

2.52e-048432M46443
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

3.23e-049432M47451
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

4.03e-0410432M27945
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

4.91e-0411432MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

4.91e-0411432M48021
PathwayKEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

C4A C4B

4.91e-0411432M47874
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

4.91e-0411432M26924
PathwayKEGG_CELL_CYCLE

CDKN2B STAG1 CREBBP EP300

5.56e-04125434M7963
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

5.88e-0412432M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

5.88e-0412432M27765
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

C3 C4A C4B

5.88e-0454433MM14655
PathwayWP_SIDS_SUSCEPTIBILITY_PATHWAYS

C4A C4B EP300

7.63e-0459433MM15838
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

8.08e-0414432M27808
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

9.31e-0415432MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

9.31e-0415432M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

9.31e-0415432MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

9.31e-0415432M953
PathwayREACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA

CREBBP EP300 DHX9

9.68e-0464433M27046
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

1.06e-0316432M27121
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.06e-0316432M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.06e-0316432MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.06e-0316432M8516
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

1.06e-0316432M27940
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

1.20e-0317432MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

1.20e-0317432M48025
PathwayKEGG_COMPLEMENT_AND_COAGULATION_CASCADES

C3 C4A C4B

1.20e-0369433M16894
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION

JMY EP300

1.35e-0318432MM15342
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

1.35e-0318432M26942
PathwayWP_SUDDEN_INFANT_DEATH_SYNDROME_SIDS_SUSCEPTIBILITY_PATHWAYS

C4A C4B CREBBP EP300

1.37e-03159434M39373
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

1.50e-0319432M18933
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION

JMY EP300

1.50e-0319432M27639
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

1.50e-0319432M46442
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

1.67e-0320432M27881
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

1.84e-0321432M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

1.84e-0321432M27485
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

C3 C4A C4B

1.84e-0380433M6121
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

CDKN2B CREBBP EP300

1.98e-0382433M2
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

2.02e-0322432MM1370
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

2.02e-0322432MM1443
PathwayREACTOME_COMPLEMENT_CASCADE

C3 C4A C4B

2.12e-0384433MM14653
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

2.21e-0323432M2821
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

CDKN2B CREBBP EP300

2.27e-0386433M2642
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

2.40e-0324432M13404
PathwayWP_ALLOGRAFT_REJECTION

C3 C4A C4B

2.50e-0389433M39398
PathwayREACTOME_SUMOYLATION

STAG1 CREBBP EP300 NSMCE4A

2.57e-03189434M27214
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

2.61e-0325432M27880
PathwayBIOCARTA_CARM_ER_PATHWAY

CREBBP EP300

2.82e-0326432M2499
PathwayPID_HDAC_CLASSIII_PATHWAY

CREBBP EP300

2.82e-0326432M32
PathwayREACTOME_ATTENUATION_PHASE

CREBBP EP300

3.27e-0328432M27254
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

WNT10A CREBBP EP300

3.58e-03101433M39387
PathwayKEGG_MELANOGENESIS

WNT10A CREBBP EP300

3.58e-03101433M7761
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

WNT10A CREBBP EP300

3.58e-03101433MM15829
PathwayPID_RETINOIC_ACID_PATHWAY

CREBBP EP300

3.74e-0330432M207
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

CREBBP EP300

3.74e-0330432M936
PathwayWP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY

C3 C4A C4B

4.10e-03106433M42535
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

CREBBP EP300

4.25e-0332432M39521
PathwayREACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA

EP300 DHX9

4.25e-0332432MM14707
Pubmed

Genetic polymorphism of murine C3 controlled by a single co-dominant locus on chromosome 17.

C3 C4A C4B

3.54e-093543681746
Pubmed

Serum complement component 3, complement component 4 and complement component 1q levels predict progressive visual field loss in older women with primary angle closure glaucoma.

C3 C4A C4B

3.54e-09354335017157
Pubmed

Genetic evidence for involvement of classical complement pathway in induction of experimental autoimmune myasthenia gravis.

C3 C4A C4B

3.54e-09354314500686
Pubmed

In vitro C3 deposition on Cryptococcus capsule occurs via multiple complement activation pathways.

C3 C4A C4B

3.54e-09354321723612
Pubmed

Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria.

C3 C4A C4B

3.54e-0935439829481
Pubmed

Three distinct profiles of serum complement C4 proteins in pediatric systemic lupus erythematosus (SLE) patients: tight associations of complement C4 and C3 protein levels in SLE but not in healthy subjects.

C3 C4A C4B

3.54e-09354316893076
Pubmed

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

C3 C4A C4B

3.54e-0935438524789
Pubmed

Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes.

C3 C4A C4B

3.54e-09354337234916
Pubmed

Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli.

C3 C4A C4B

3.54e-09354311433344
Pubmed

Immune complex glomerulonephritis in C4- and C3-deficient mice.

C3 C4A C4B

3.54e-0935439461092
Pubmed

Regulation of the B cell response to T-dependent antigens by classical pathway complement.

C3 C4A C4B

3.54e-0935438752901
Pubmed

Increased susceptibility to endotoxin shock in complement C3- and C4-deficient mice is corrected by C1 inhibitor replacement.

C3 C4A C4B

3.54e-0935439218619
Pubmed

Complement genes contribute sex-biased vulnerability in diverse disorders.

C3 C4A C4B

3.54e-09354332499649
Pubmed

Role of complement in a murine model of peanut-induced anaphylaxis.

C3 C4A C4B

3.54e-09354323182714
Pubmed

Impaired mast cell-dependent natural immunity in complement C3-deficient mice.

C3 C4A C4B

1.41e-0845439367154
Pubmed

The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia.

C3 C4A C4B

1.41e-08454315102802
Pubmed

Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells.

C3 C4A C4B

1.41e-08454316304047
Pubmed

Efficient amyloid A clearance in the absence of immunoglobulins and complement factors.

C3 C4A C4B

1.41e-08454323454183
Pubmed

The human complement system: assembly of the classical pathway C3 convertase.

C3 C4A C4B

1.41e-0845436906228
Pubmed

Functional analysis of Ficolin-3 mediated complement activation.

C3 C4A C4B

1.41e-08454321085669
Pubmed

Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice.

C3 C4A C4B

1.41e-0845439409643
Pubmed

Complement C4 is protective for lupus disease independent of C3.

C3 C4A C4B

1.41e-08454311801636
Pubmed

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo.

C3 C4A C4B

1.41e-08454310934224
Pubmed

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis.

C3 C4A C4B

1.41e-08454330301856
Pubmed

Allelic distribution of complement components BF, C4A, C4B, and C3 in Psoriasis vulgaris.

C3 C4A C4B

1.41e-08454311803045
Pubmed

Intestinal reperfusion injury is mediated by IgM and complement.

C3 C4A C4B

1.41e-08454310066708
Pubmed

Antigen localization within the splenic marginal zone restores humoral immune response and IgG class switch in complement C4-deficient mice.

C3 C4A C4B

1.41e-08454315477230
Pubmed

Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells.

C3 C4A C4B

1.41e-08454319302245
Pubmed

Evidence for non-traditional activation of complement factor C3 during murine liver regeneration.

C3 C4A C4B

1.41e-08454318452991
Pubmed

Phylogeny of the C3/C4/C5 complement-component gene family indicates that C5 diverged first.

C3 C4A C4B

1.41e-0845438015436
Pubmed

Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency.

C3 C4A C4B

3.53e-08554325039245
Pubmed

Both complement and IgG fc receptors are required for development of attenuated antiglomerular basement membrane nephritis in mice.

C3 C4A C4B

3.53e-08554319710463
Pubmed

The generation of thymus-independent germinal centers depends on CD40 but not on CD154, the T cell-derived CD40-ligand.

C3 C4A C4B

3.53e-08554316783845
Pubmed

Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction.

C3 C4A C4B

3.53e-08554318056835
Pubmed

Complement proteins C3 and C4 bind to collagen and elastin in the vascular wall: a potential role in vascular stiffness and atherosclerosis.

C3 C4A C4B

3.53e-08554321707943
Pubmed

Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia.

C3 C4A C4B

3.53e-08554315192652
Pubmed

A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis.

C3 C4A C4B

3.53e-0855439382884
Pubmed

Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.

C3 C4A C4B

3.53e-08554329743491
Pubmed

Protective T cell-independent antiviral antibody responses are dependent on complement.

C3 C4A C4B

3.53e-08554310523614
Pubmed

Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.

C3 C4A C4B

3.53e-08554317947689
Pubmed

Formation of high affinity C5 convertase of the classical pathway of complement.

C3 C4A C4B

3.53e-08554312878586
Pubmed

The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria.

C3 C4A C4B

3.53e-08554322689574
Pubmed

Predominant role for C5b-9 in renal ischemia/reperfusion injury.

C3 C4A C4B

3.53e-08554310811844
Pubmed

Complement C4A Regulates Autoreactive B Cells in Murine Lupus.

C3 C4A C4B

3.53e-08554333147456
Pubmed

CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression.

C3 C4A C4B

7.05e-08654319710450
Pubmed

Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice.

C3 C4A C4B

7.05e-08654317363917
Pubmed

Modulation of the antitumor immune response by complement.

C3 C4A C4B

7.05e-08654318820683
Pubmed

Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro.

C3 C4A C4B

7.05e-08654315597324
Pubmed

A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q.

C3 C4A C4B

7.05e-08654316615889
Pubmed

Complement component C3 binds to activated normal platelets without preceding proteolytic activation and promotes binding to complement receptor 1.

C3 C4A C4B

1.23e-07754320139276
Pubmed

Protection from Streptococcus pneumoniae infection by C-reactive protein and natural antibody requires complement but not Fc gamma receptors.

C3 C4A C4B

1.23e-07754312055255
Pubmed

A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3.

C3 C4A C4B

1.23e-07754322037602
Pubmed

Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking.

C3 C4A C4B

1.23e-07754329233958
Pubmed

Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis.

C3 C4A C4B

1.97e-07854320870940
Pubmed

Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A(H1N1) 2009 virus infection.

C3 C4A C4B

1.97e-07854328301559
Pubmed

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping.

C3 C4A C4B

1.97e-07854330173917
Pubmed

Divergent immunoglobulin g subclass activity through selective Fc receptor binding.

C3 C4A C4B

1.97e-07854316322460
Pubmed

Impaired antibody response causes persistence of prototypic T cell-contained virus.

C3 C4A C4B

1.97e-07854319355789
Pubmed

C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens.

C3 C4A C4B

1.97e-07854324474777
Pubmed

Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.

C3 C4A C4B

1.97e-07854314670299
Pubmed

The role of complement in cryoglobulin-induced immune complex glomerulonephritis.

C3 C4A C4B

1.97e-07854316272350
Pubmed

Surviving mousepox infection requires the complement system.

C3 C4A C4B

2.95e-07954319112490
Pubmed

Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement.

C3 C4A C4B

4.21e-071054321943708
Pubmed

Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.

C3 C4A C4B

4.21e-071054330429287
Pubmed

Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.

C3 C4A C4B

5.79e-071154323204401
Pubmed

Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg.

C3 C4A C4B

7.71e-071254318524992
Pubmed

The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity.

C3 C4A C4B

7.71e-071254331801071
Pubmed

Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17.

C3 C4A C4B

1.00e-06135431970332
Pubmed

Blocking properdin, the alternative pathway, and anaphylatoxin receptors ameliorates renal ischemia-reperfusion injury in decay-accelerating factor and CD59 double-knockout mice.

C3 C4A C4B

1.00e-061354323427256
Pubmed

Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position.

C3 C4A C4B

1.59e-06155432885372
Pubmed

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.

STAG1 CREBBP EP300

1.95e-061654322780989
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

2.37e-06254227881875
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

2.37e-06254222737222
Pubmed

The early predictive role of complement C3 and C4 in patients with acute pancreatitis.

C3 C4A

2.37e-06254232187754
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

2.37e-06254216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

2.37e-06254215998580
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

2.37e-0625427373044
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

2.37e-06254219062096
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

2.37e-06254234845315
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

2.37e-0625423696167
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

2.37e-0625421357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

2.37e-06254216098595
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

2.37e-06254219729597
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

2.37e-06254219933335
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

2.37e-06254215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

2.37e-06254229460469
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

2.37e-0625422459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

2.37e-06254217645767
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

2.37e-06254215787745
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

2.37e-06254212207352
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

2.37e-06254224551300
Pubmed

Centenarian longevity is positively correlated with IgE levels but negatively correlated with C3/C4 levels, abdominal obesity and metabolic syndrome.

C3 C4A

2.37e-06254232132668
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

2.37e-06254230026462
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

2.37e-0625426559257
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

2.37e-06254227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

2.37e-06254222387014
Pubmed

C4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3.

C3 C4B

2.37e-06254218682851
Pubmed

Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.

C4A C4B

2.37e-06254234299197
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

2.37e-06254233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

2.37e-0625429018065
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C3 C4A C4B

9.01e-0794131234
GeneFamilyComplement system|Sushi domain containing

C3 C4A C4B

7.34e-0536413492
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

6.68e-0417412486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

7.50e-041841291
GeneFamilyNucleoporins

DDX19B DDX19A

2.38e-03324121051
GeneFamilyGlycosyltransferase family 6|Blood group antigens

C4A C4B

3.18e-0337412454
GeneFamilyDEAD-box helicases

DDX19B DDX19A

4.08e-0342412499
GeneFamilyAAA ATPases

KATNAL2 RFC1

6.43e-0353412413
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 STAG1 PNN MYO9A DHX9

2.34e-06176545749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP1B1 MYH6 RNASE1 KCNG4 ARHGAP29

2.99e-061855450ab1be455f2cd883c9d1522ca78112c37833352e
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

WSB1 STAG1 C3 ADAMTSL3 UST

3.87e-06195545ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 MYO9A PKHD1 ARHGAP29 WNT10A

4.27e-061995452e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29 TUB

2.73e-051435447a7a9829ba63468c9745904d9e993590051207ab
ToppCellfacs-Liver|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMDHD1 TTC36 C3 C4B

4.04e-05158544ea7db6bd9742153ceb6e444892a6d1df9c7fcc96
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_F|PND01-03-samps / Age Group, Lineage, Cell class and subclass

AJAP1 C4A ADAMTSL3 NR2F1

5.37e-0517054471718dcebd48105994c313bb55babc70301170a0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29 TUB

5.37e-051705445d5f208682be21ed58320f5fc083a7898f8712da
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCNG4 RFC1 ADAMTSL3 NR2F1

5.62e-0517254403a0aff6b7971093a4347b5ed12546d78374c56f
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDKN2B AJAP1 MYO9A PKHD1

6.28e-051775449af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDKN2B RNASE1 PKHD1 C3

6.42e-05178544f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C3 ADAMTSL3 TUB NR2F1

6.56e-05179544dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29 TUB

6.85e-05181544071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29 TUB

7.15e-05183544738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29 TUB

7.15e-0518354492fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

C3 C4A C4B NR2F1

7.45e-0518554423579988036fc1925992c31919750f9b3fe9f790
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 C4B ADAMTSL3 B4GALT1

7.61e-05186544ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

STAG1 CREBBP EP300 IWS1

7.61e-0518654403db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 ADAMTSL3 UST NR2F1

7.93e-05188544ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

C3 C4A C4B NR2F1

8.10e-0518954479bb2593ad5d17f94b17972884241f03a0f43770
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C4B LRRTM3 ADAMTSL3

8.10e-051895446b3b42d758b63a0df62310c34fa3bde421c1afd7
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C4B LRRTM3 ADAMTSL3

8.10e-05189544344b23d3c47d0665dda1cd4856a5e72f1c28cfb3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29 ADAMTSL3

8.26e-051905441cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 ADAMTSL3 UST NR2F1

8.26e-05190544efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29 WNT10A

8.26e-051905443fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29 ADAMTSL3

8.26e-0519054459bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C3 C4B UST

8.43e-051915449214655dca96d766737c9f30b624d7fe7050342e
ToppCellfacs-Trachea-nan-18m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C3 C4B ADAMTSL3

8.43e-05191544783e8c436de90623bb1bc4117270d60c8c8a9461
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C3 C4B ADAMTSL3

8.60e-05192544853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C3 C4B ADAMTSL3

8.60e-05192544d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C3 C4B ADAMTSL3

8.60e-0519254449281626ecad0456fdbded2378b7028d7b589686
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AJAP1 MYO9A PKHD1 ARHGAP29

8.78e-0519354480e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AJAP1 MYO9A PKHD1 ARHGAP29

8.78e-05193544b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AJAP1 MYO9A PKHD1 ARHGAP29

8.78e-05193544263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

C3 ADAMTSL3 UST NR2F1

8.95e-05194544c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

C3 ADAMTSL3 TUB B4GALT1

9.13e-05195544ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellAT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

WSB1 CYP1B1 RNASE1 C3

9.13e-05195544bb45a17871a8a2593bc16a95f22e3c239c49985b
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C3 ADAMTSL3 NR2F1

9.32e-051965446bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 C3 ADAMTSL3 NR2F1

9.32e-05196544c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell(05)_Secretory|World / shred by cell type by condition

WSB1 RNASE1 C3 B4GALT1

9.32e-051965448032c25b51ef96aeba28cc52686a2bd45213453d
ToppCell(4)_Endothelial_cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CYP1B1 RNASE1 ARHGAP29 NR2F1

9.50e-05197544dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell(5)_Fibroblasts-(5)_Fibroblast-F|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CDKN2B CYP1B1 C3 ADAMTSL3

9.50e-05197544fbff2fb7a8142b88c9dc71aa10980f4350b7e081
ToppCell(4)_Blood_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CYP1B1 RNASE1 ARHGAP29 NR2F1

9.50e-051975441b82979a41ef46c814c82527a585900586d71260
ToppCellILEUM-non-inflamed-(7)_ACKR1+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CYP1B1 RNASE1 ARHGAP29 NR2F1

9.69e-05198544f8a6a75c9f2fbe32a22b14b6a029411c73c09f68
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CYP1B1 C4A C4B NR2F1

9.69e-051985447a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCellBiopsy_Control_(H.)-Mesenchymal-Mesothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

C3 C4A C4B NR2F1

9.88e-05199544ca970114b5aef4518ce580897a62ac88688b2671
ToppCell(5)_Fibroblast-F|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CYP1B1 C3 ADAMTSL3 NR2F1

9.88e-051995441f66db4f502de4a5159cde90fcb3befb26b8d375
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

CDKN2B PNN ANKRD11 RFC1

9.88e-05199544a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC4AP PTPRA ADO ANKRD11

1.01e-04200544fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CYP1B1 C3 C4B NR2F1

1.01e-0420054436de49593cf6ff1c9229fcceb150c1d68658a360
ToppCellcellseq2-Mesenchymal-Fibroblastic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP1B1 C3 ADAMTSL3 NR2F1

1.01e-042005441c10597edd532bf172ca09870a937d35e2585081
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP1B1 C3 ADAMTSL3 NR2F1

1.01e-04200544440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP1B1 C3 ADAMTSL3 NR2F1

1.01e-0420054444317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCellLung_Parenchyma|World / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNASE1 ARHGAP29 C3 NR2F1

1.03e-0420154491ec5eebe93a3c7b1a33c27e5da949b123b676a8
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C3 C4B NR2F1

1.90e-049254384ac97a16920b912a67ea80e71146eddf9dfa92f
ToppCellThalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)|Thalamus / BrainAtlas - Mouse McCarroll V32

RNASE1 C4A CA5B

2.51e-041015431d74f6b30d23e942f26fc57665b5c533ff0c089f
ToppCellThalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--|Thalamus / BrainAtlas - Mouse McCarroll V32

RNASE1 C4A CA5B

2.51e-04101543578946c048084f48a74d4352743017f04039d5e8
ToppCellThalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-|Thalamus / BrainAtlas - Mouse McCarroll V32

RNASE1 C4A CA5B

2.51e-041015438a3b8abe06a8c5b546ce40c9429401058fe671d7
ToppCellControl-NK_activated|Control / Disease condition and Cell class

DOC2A KCNG4 C3

4.06e-041195430d0bab03d56e269c6e637b0bbeffe9d1491dfc33
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOC2A C3 C4A

6.25e-04138543d5342383c5e52b92c39d7afe76560501be3ea5cd
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOC2A C3 C4A

6.25e-04138543e2659949944bdf39b23c7275e380a7a937e2726c
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|healthy_donor / Disease condition, Lineage, Cell class and subclass

KATNAL2 WNT10A ADAMTSL3

6.25e-0413854397f5dc17522462133e582b508ad0ef036e656872
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOC2A CYP1B1 RNASE1

8.58e-04154543ec56b7fb88e39041416c384f371c767f3b4e92fa
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMDHD1 TTC36 C4A

9.07e-041575435af1b77dd08cf7f3b629e0f59defdf1ebee5cc3e
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP1B1 KATNAL2 C3

9.07e-04157543c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 ARHGAP29

9.24e-041585431cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

DOC2A WNT10A NR2F1

9.41e-0415954318e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH6 CELSR2 NR2F1

9.41e-04159543cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH6 CELSR2 NR2F1

9.41e-04159543330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC36 C3 C4B

9.76e-04161543274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCelldroplet-Heart-4Chambers|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 MYH6 HHATL

9.93e-041625435625ec6dae204d5537883f05ea546970628d10bb
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

WSB1 PHF7 UST

1.01e-031635431e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma|TCGA-Endometrium / Sample_Type by Project: Shred V9

CDKN2B ARHGAP29 WNT10A

1.03e-0316454308c725548e751f815b4df778607270498204b353
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WSB1 RNASE1 C3

1.03e-03164543b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A PKHD1 C3

1.03e-031645431cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WSB1 RNASE1 C3

1.03e-031645433aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AJAP1 ARHGAP29 TUB

1.03e-03164543382e42701779d12a7948690b3be72d06dd75c8b4
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC36 UST TAB3

1.03e-03164543f9a2cc12179d5621c9174ec01d7418a71edd28d1
ToppCellfacs-Kidney-nan-24m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 KCNG4 AMDHD1

1.05e-03165543c746bb22ef52d7f7fa6ee9c37ae6bbe0ccce718e
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 C4B B4GALT1

1.05e-03165543f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCellfacs-Kidney-nan-24m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 KCNG4 AMDHD1

1.05e-031655434cdd80580d5638fd649280ba3893251c2f898f3f
ToppCellControl-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

C3 C4A C4B

1.07e-0316654332ebaefa6c074b28193fff764ee7c2c0e9357e20
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOC2A PNN C4A

1.07e-0316654366026988509e39e41274fa0de738383219e8ff30
ToppCellControl-Epithelial-Mesothelial|Control / Disease state, Lineage and Cell class

C3 C4A C4B

1.07e-031665431ed3788257e14f097862b999f020bfe2a57de52b
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ARHGAP29 ADAMTSL3 NR2F1

1.08e-031675436a03d16165e0b003092c39972928981abd4a75aa
ToppCellfacs-Tongue-nan-24m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN2B C3 C4B

1.08e-0316754373fdf4b81a45ec686d2929eaf641b434f70b7898
ToppCellfacs-Tongue-nan-24m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN2B C3 C4B

1.08e-03167543c4157fb31b44fe7c44be4215dda8ae2d37cf49a8
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT10A ADAMTSL3 TUB

1.12e-03169543c5015ddb838849ea892a2cae5a739b554eb6d793
ToppCellfacs-Tongue-nan-24m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN2B C3 C4B

1.12e-031695430054f9bfd4d377c7fd94873c1308622051c59a8e
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX19A C4B TAB3

1.14e-0317054337c647f67505aa1ff12a198df1eeddd9f406fe15
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP1B1 ARHGAP29 NR2F1

1.14e-031705434848965bc7e9356c6601bb41eeea1553d2eea87e
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX19A C4B TAB3

1.14e-03170543b180ec9a1b79025a180c8559c27c31272410dea8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOC2A KCNG4 WNT10A

1.16e-03171543d07e2c5f7d7f12c68860d4161d76372de174f1d8
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNASE1 C3 LRRTM3

1.16e-03171543d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNASE1 C3 LRRTM3

1.16e-03171543fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNASE1 C3 LRRTM3

1.16e-03171543d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

URB1 KCNG4 CA5B

1.16e-03171543846a9acfff0bf0a9baf65dc07b7d7a9217ed6598
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNASE1 C3 LRRTM3

1.16e-031715434347e6f62c04ea43299893ad4b79719049009a56
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT10A ADAMTSL3 TUB

1.16e-0317154320ac3de9c164b409b70a30a8b6544ea491ef7c0e
ToppCellfacs-Heart-RV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMDHD1 WNT10A CNR2

1.18e-031725432dcc9d67d6ecc35940eabbc8ed528f5f884f6976
ComputationalComplement.

C3 C4A C4B

5.84e-0523363MODULE_130
DrugRapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A

WSB1 CDKN2B CYP1B1 ABCA2 UST CNR2

5.05e-061935264431_UP
DrugNSC56408

DDX19B ADO C3 TUB

1.22e-0562524CID000005604
Drug2-aminothiophenol

C4A C4B

1.53e-053522ctd:C005464
Drugsodium;isothiocyanate

DDX19B RNASE1 DHX9

1.93e-0523523CID010953423
DrugPhe-gly

DDX19B CDKN2B CREBBP EP300

2.34e-0573524CID000098207
DrugC3 P

RNASE1 ADO C3

2.49e-0525523CID000066535
Drug3-O-methyl-6-deoxy-d-talose

ABCA2 DHX9

3.06e-054522CID000150840
DrugSA-3

RNASE1 STAG1 DHX9

3.54e-0528523CID000657084
Drug3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide

CREBBP EP300

5.09e-055522ctd:C575894
DrugRS)-AHPA

ADO C3

5.09e-055522CID000146832
Drug3'-dCTP

STAG1 C4A CREBBP EP300

5.35e-0590524CID000153054
Drugcytosine

WSB1 CDKN2B CYP1B1 RNASE1 ADO C3 SPPL2C

6.15e-05441527CID000000597
DrugAlprostadil [745-65-3]; Up 200; 11.2uM; PC3; HT_HG-U133A

ABCA2 PHF7 C3 UST B4GALT1

7.08e-051895254099_UP
Drugcornin

RNASE1 C3

7.63e-056522CID000073467
Drug5213008; Up 200; 18uM; MCF7; HT_HG-U133A_EA

WSB1 CYP1B1 PTPRA B4GALT1 DHX9

8.01e-05194525898_UP
DrugDubinidine [22964-77-8]; Up 200; 14.6uM; PC3; HT_HG-U133A

DOC2A CYP1B1 CA5B CNR2 B4GALT1

8.01e-051945255774_UP
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A

WSB1 ABCA2 PTPRA CELSR2 EP300

8.41e-051965251666_UP
DrugHydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A

WSB1 CYP1B1 URB1 AJAP1 CREBBP

8.61e-051975253292_UP
DrugDihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; PC3; HT_HG-U133A

CYP1B1 C3 CA5B UST B4GALT1

8.61e-051975254502_UP
DrugLiothyronine [6893-02-3]; Up 200; 6.2uM; MCF7; HT_HG-U133A

URB1 AJAP1 CA5B NR2F1 CNR2

8.82e-051985253324_UP
DrugHexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; PC3; HG-U133A

CYP1B1 DDX19A ANKRD11 NR2F1 B4GALT1

9.03e-051995251901_DN
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

WSB1 AJAP1 CA5B CREBBP NR2F1

9.25e-052005253354_UP
Drugkanamycin A derivative

MYH6 RNASE1

1.07e-047522CID000499917
Drug2-Kddha

C4A DHX9

1.07e-047522CID000127425
Drugaa 2

RNASE1 STAG1 C3

1.13e-0441523CID000447622
DiseaseMenke-Hennekam syndrome

CREBBP EP300

3.29e-062542cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

3.29e-062542DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

3.29e-062542cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.29e-062542C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.29e-062542180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

3.29e-062542cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

3.29e-062542DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

3.29e-062542C0035934
DiseaseComplement deficiency disease

C3 C4A C4B

3.04e-0533543C0272242
Diseasesystemic lupus erythematosus (implicated_via_orthology)

C4A C4B EP300

6.79e-0543543DOID:9074 (implicated_via_orthology)
DiseaseLymphoma, Lymphocytic, Intermediate

ARHGAP29 WNT10A

1.79e-0411542C0751958
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

CYP1B1 CREBBP EP300

1.93e-0461543C1961102
Diseasesystemic lupus erythematosus (is_implicated_in)

C3 C4A C4B

2.03e-0462543DOID:9074 (is_implicated_in)
Diseasedevelopmental dysplasia of the hip

AJAP1 ADAMTSL3

3.88e-0416542EFO_1000648
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

ARHGAP29 WNT10A

3.88e-0416542C0334634
Diseasebasal cell carcinoma

CYP1B1 RNASE1 TRPC4AP ANKRD11

4.02e-04189544EFO_0004193
DiseaseAntibody Deficiency Syndrome

C3 C4A

4.39e-0417542C0003257
DiseaseImmunologic Deficiency Syndromes

C3 C4A

8.11e-0423542C0021051
Diseasesuntan

CYP1B1 TRPC4AP ANKRD11

9.00e-04103543EFO_0004279
Diseasekeratinocyte carcinoma

CYP1B1 RNASE1 ANKRD11

1.33e-03118543EFO_0010176
Diseasetotal blood protein measurement

TRPC4AP ADO STAG1 PKHD1 ARHGAP29

1.37e-03449545EFO_0004536
Diseasecoronary artery disease

CDKN2B CYP1B1 RNASE1 TRPC4AP CELSR2 STAG1 PKHD1 TUB

1.40e-031194548EFO_0001645
Diseasecutaneous melanoma

CDKN2B CYP1B1 ANKRD11

1.43e-03121543EFO_0000389
DiseaseSquamous cell carcinoma

CYP1B1 CREBBP EP300

1.54e-03124543C0007137
DiseaseC-reactive protein measurement, high density lipoprotein cholesterol measurement

CELSR2 STAG1

1.78e-0334542EFO_0004458, EFO_0004612

Protein segments in the cluster

PeptideGeneStartEntry
PSQFRDILRRQQMMQ

EP300

2176

Q09472
MSISRPNAVVGRCRM

B4GALT1

326

P15291
RMVDNFRPLQPLMNR

CA5B

276

Q9Y2D0
EIPQRMTRNRAQMLA

ANKRD11

2331

Q6UB99
PMMRSCEQRAARVQQ

C4B

711

P0C0L5
MPRDNMASLIQRIAR

ADO

1

Q96SZ5
MAGNKMFCRPRRQRL

H2AL3

1

A0A3B3IU63
VERIHGQMQMPRARR

AJAP1

86

Q9UKB5
RRRMATMNTRNVPQQ

CREBBP

1866

Q92793
DGMRENPMRFSCQRR

C3

696

P01024
PVRMRQFVGCMRNLQ

CELSR2

1536

Q9HCU4
HQDRQVPGMARMRLD

CNR2

226

P34972
MRREAVQRGRMPPTQ

NR2F1

151

P10589
QRDLEQMPQRRRMNS

IWS1

706

Q96ST2
VQMSRRVRALFGAMN

HHATL

421

Q9HCP6
PFRDMRELAMLRRQQ

JMY

386

Q8N9B5
MGCRSRAITQGRRVM

FLYWCH1

546

Q4VC44
GMVQELLRMVRQGRR

LRRC75A

56

Q8NAA5
GLCMNRLREMVENPQ

KCNG4

201

Q8TDN1
EQINKMEARPRRQSM

PNN

276

Q9H307
LPQRSRGKTRRMMND

KATNAL2

101

Q8IYT4
FINARRRMVQPMIDQ

MEIS3P2

296

A8K0S8
RRMVQPMIDQSNRIG

MEIS3P2

301

A8K0S8
QRVLPRMQARMRGFQ

MYO15B

356

Q96JP2
NPMCQRPRLKRMQQF

ARHGAP29

1236

Q52LW3
MRGRRGDRMTINIQE

DOC2A

1

Q14183
QSIRIQRMLPRNCQM

DDX19B

256

Q9UMR2
NGVNRFGRRAIQVMM

CDKN2B

41

P42772
TIMCQYNFLRRPQRM

ABCA2

2006

Q9BZC7
RSLQQRLQCMMRAGT

AMDHD1

136

Q96NU7
MMRNFFTRQPRSRQV

CYP1B1

151

Q16678
SIRIQRMLPRNCQML

DDX19A

256

Q9NUU7
PMMRSCEQRAARVQQ

C4A

711

P0C0L4
PVNERMLNMIRQISR

DHX9

1126

Q08211
RIRAQRCQMVQTDMQ

PTPRA

476

P18433
PRVRSHVSRQAMQGM

MTA3

436

Q9BTC8
CVLLMGRQRNQVHRM

TRPC4AP

396

Q8TEL6
PEEMTRLRSMNRQLQ

TAB3

571

Q8N5C8
PASMKQLQQRSLMRR

LRRTM3

446

Q86VH5
QCNNRKEFPQEMLRM

PHF7

206

Q9BWX1
RFQRPRVEQIKGAMM

RFC1

771

P35251
QRPLRQTTAMVMRGN

SPPL2C

86

Q8IUH8
VIQEERAMPAQLRRM

NSMCE4A

241

Q9NXX6
YRRVGQRRPLMMEMN

PKHD1

3631

P08F94
IITRMQAQARGQLMR

MYH6

786

P13533
QMMRRRNMTQGRCKP

RNASE1

56

P07998
RMMQTILHFPQNRRL

URB1

1601

O60287
QNHMIRTPSMRQEER

UST

211

Q9Y2C2
RGTVRIEMFRNMQNA

STAG1

131

Q8WVM7
CNRMLADMMGQLRRP

TTC36

171

A6NLP5
CRMSIRRVMPTQEVQ

WSB1

391

Q9Y6I7
NNRVGRQAVMENMRR

WNT10A

246

Q9GZT5
GMNMVHERVSIRPRN

TUB

391

P50607
NRCPGRCMGRAVRMQ

ADAMTSL3

1551

P82987
RCMGRAVRMQQRHTA

ADAMTSL3

1556

P82987
RRRMMERGFLPQPQQ

MYO9A

131

B2RTY4