Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncomplement component C1q complex binding

C4A C4B

3.19e-0410542GO:0001849
GeneOntologyMolecularFunctionstructural constituent of eye lens

CRYGC CRYGD

1.91e-0324542GO:0005212
GeneOntologyMolecularFunctionopsonin binding

C4A C4B

2.07e-0325542GO:0001846
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCNA5 KCNT2

2.41e-0327542GO:0015271
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM6A JMJD1C

2.59e-0328542GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM6A JMJD1C

3.17e-0331542GO:0032452
GeneOntologyMolecularFunctioncomplement binding

C4A C4B

3.38e-0332542GO:0001848
GeneOntologyMolecularFunctionprotein demethylase activity

KDM6A JMJD1C

3.38e-0332542GO:0140457
GeneOntologyCellularComponentpresynaptic active zone membrane

LRFN1 TENM3 RIMS1 GRM4

4.57e-0578534GO:0048787
GeneOntologyCellularComponentsymbiont cell surface

C4A C4B

1.75e-048532GO:0106139
GeneOntologyCellularComponentother organism part

C4A C4B

2.24e-049532GO:0044217
GeneOntologyCellularComponentpresynaptic active zone

LRFN1 TENM3 RIMS1 GRM4

4.49e-04141534GO:0048786
GeneOntologyCellularComponentdendrite

SLITRK2 PNMT YBX1 C4A C4B INPP5F N4BP3 GRM4

1.34e-03858538GO:0030425
GeneOntologyCellularComponentdendritic tree

SLITRK2 PNMT YBX1 C4A C4B INPP5F N4BP3 GRM4

1.36e-03860538GO:0097447
GeneOntologyCellularComponentaxon

PNMT TENM3 C4A C4B IRX3 INPP5F N4BP3 GRM4

1.71e-03891538GO:0030424
HumanPhenoAbnormal uvea morphology

RLBP1 CRYGC CRYGD TENM3 LOXL1 ADAMTS18 C4A FGFR1 RIMS1 SPRTN KDM6A JMJD1C

2.70e-059651912HP:0000553
HumanPhenoAbnormal anterior chamber morphology

RLBP1 CRYGC CRYGD TENM3 LOXL1 ADAMTS18 FGFR1 SPRTN KDM6A

2.96e-05500199HP:0000593
HumanPhenoMicrocornea

CRYGC CRYGD TENM3 ADAMTS18 KDM6A

1.01e-04134195HP:0000482
HumanPhenoDecreased corneal diameter

CRYGC CRYGD TENM3 ADAMTS18 KDM6A

1.01e-04134195HP:0100688
HumanPhenoAbnormal cornea morphology

RLBP1 CRYGC CRYGD ARID1B TENM3 ADAMTS18 C4A FGFR1 KDM6A JMJD1C

1.10e-047441910HP:0000481
HumanPhenoOcular anterior segment dysgenesis

RLBP1 CRYGC CRYGD TENM3 ADAMTS18 FGFR1 SPRTN KDM6A

1.21e-04456198HP:0007700
DomainAnaphylatoxin_comp_syst

C4A C4B

8.16e-055542IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

8.16e-055542IPR001840
DomainCOLD_SHOCK

YBX1 YBX3

1.22e-046542PS00352
DomainCold-shock_CS

YBX1 YBX3

1.22e-046542IPR019844
DomainANATO

C4A C4B

1.71e-047542SM00104
DomainANATO

C4A C4B

1.71e-047542PF01821
DomainANAPHYLATOXIN_2

C4A C4B

1.71e-047542PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.71e-047542PS01177
DomainAnaphylatoxin/fibulin

C4A C4B

1.71e-047542IPR000020
DomainCSP

YBX1 YBX3

2.27e-048542SM00357
DomainCold_shock_prot

YBX1 YBX3

2.27e-048542IPR011129
DomainCSD

YBX1 YBX3

2.27e-048542PF00313
DomainThiol-ester_cl

C4A C4B

2.27e-048542PF10569
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

2.27e-048542IPR019565
DomainMacrogloblnA2_CS

C4A C4B

2.27e-048542IPR019742
DomainCSP_DNA-bd

YBX1 YBX3

2.27e-048542IPR002059
DomainA2M_N

C4A C4B

3.64e-0410542PF01835
DomainA2M_N

C4A C4B

3.64e-0410542IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

3.64e-0410542IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

3.64e-0410542PS00477
DomainA2M

C4A C4B

3.64e-0410542PF00207
DomainA2M_N_2

C4A C4B

3.64e-0410542IPR011625
DomainA2M_comp

C4A C4B

3.64e-0410542IPR011626
DomainA2M_N_2

C4A C4B

3.64e-0410542PF07703
DomainA2M_recep

C4A C4B

3.64e-0410542PF07677
DomainA2M_comp

C4A C4B

3.64e-0410542PF07678
DomainMacroglobln_a2

C4A C4B

3.64e-0410542IPR001599
DomainCRYSTALLIN_BETA_GAMMA

CRYGC CRYGD

8.41e-0415542PS50915
DomainCrystall

CRYGC CRYGD

8.41e-0415542PF00030
DomainBeta/gamma_crystallin

CRYGC CRYGD

8.41e-0415542IPR001064
DomainXTALbg

CRYGC CRYGD

8.41e-0415542SM00247
DomainC345C

C4A C4B

1.09e-0317542SM00643
DomainG_crystallin-rel

CRYGC CRYGD

1.22e-0318542IPR011024
DomainTerpenoid_cyclase/PrenylTrfase

C4A C4B

1.22e-0318542IPR008930
DomainNTR

C4A C4B

1.36e-0319542PF01759
DomainNetrin_module_non-TIMP

C4A C4B

1.36e-0319542IPR018933
DomainNTR

C4A C4B

2.00e-0323542PS50189
DomainNetrin_domain

C4A C4B

2.00e-0323542IPR001134
DomainJmjC

KDM6A JMJD1C

2.17e-0324542PF02373
DomainCys-rich_flank_reg_C

LRFN1 SLITRK2 ADGRA3

2.25e-0390543IPR000483
DomainLRRCT

LRFN1 SLITRK2 ADGRA3

2.25e-0390543SM00082
DomainTIMP-like_OB-fold

C4A C4B

2.55e-0326542IPR008993
DomainJMJC

KDM6A JMJD1C

3.85e-0332542PS51184
DomainJmjC_dom

KDM6A JMJD1C

3.85e-0332542IPR003347
DomainJmjC

KDM6A JMJD1C

4.09e-0333542SM00558
Domain-

RC3H1 DUS3L

5.97e-03405424.10.1000.10
Domainzf-CCCH

RC3H1 DUS3L

8.85e-0349542PF00642
PathwayREACTOME_ACTIVATION_OF_C3_AND_C5

C4A C4B

1.47e-047382MM14685
PathwayREACTOME_ACTIVATION_OF_C3_AND_C5

C4A C4B

1.96e-048382M27031
PathwayKEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

C4A C4B

1.96e-048382M47872
PathwayBIOCARTA_LECTIN_PATHWAY

C4A C4B

3.83e-0411382MM1430
PathwayKEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

C4A C4B

3.83e-0411382M47874
PathwayBIOCARTA_CLASSIC_PATHWAY

C4A C4B

4.59e-0412382MM1368
PathwayWP_SIDS_SUSCEPTIBILITY_PATHWAYS

YBX1 C4A C4B

5.29e-0459383MM15838
PathwayBIOCARTA_LECTIN_PATHWAY

C4A C4B

5.42e-0413382M4732
PathwayBIOCARTA_CLASSIC_PATHWAY

C4A C4B

7.27e-0415382M7146
PathwayWP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY

C4A C4B

9.38e-0417382MM15944
PathwayBIOCARTA_COMP_PATHWAY

C4A C4B

9.38e-0417382MM1369
PathwayBIOCARTA_COMP_PATHWAY

C4A C4B

1.30e-0320382M917
Pubmed

Molecular genetics of the human MHC complement gene cluster.

DXO C4A C4B

1.97e-07854310072631
Pubmed

Organizations and gene duplications of the human and mouse MHC complement gene clusters.

DXO C4A C4B

5.79e-071154310686478
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

2.37e-06254222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

2.37e-06254216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

2.37e-06254215998580
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

2.37e-06254225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

2.37e-06254217728371
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

2.37e-0625427373044
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

2.37e-06254219062096
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

2.37e-0625423696167
Pubmed

Structure and organization of the C4 genes.

C4A C4B

2.37e-0625426149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

2.37e-0625426149581
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

2.37e-0625421357031
Pubmed

A locus for a human hereditary cataract is closely linked to the gamma-crystallin gene family.

CRYGC CRYGD

2.37e-0625423025877
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

2.37e-06254216098595
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

2.37e-06254219933335
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

2.37e-06254212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

2.37e-0625423542363
Pubmed

Differential distribution of Y-box-binding protein 1 and cold shock domain protein A in developing and adult human brain.

YBX1 YBX3

2.37e-06254224817634
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

2.37e-0625422387317
Pubmed

Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.

C4A C4B

2.37e-0625428132550
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

2.37e-0625422459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

2.37e-06254217645767
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

2.37e-06254215787745
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

2.37e-06254212207352
Pubmed

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.

TPSAB1 TPSB2

2.37e-0625429521329
Pubmed

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.

C4A C4B

2.37e-0625422395880
Pubmed

The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.

TPSAB1 TPSB2

2.37e-06254210500112
Pubmed

Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.

C4A C4B

2.37e-06254226814708
Pubmed

cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).

C4A C4B

2.37e-0625426192448
Pubmed

Complete primary structure of human C4a anaphylatoxin.

C4A C4B

2.37e-0625426167582
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

2.37e-06254216908004
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

2.37e-06254230026462
Pubmed

Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.

C4A C4B

2.37e-0625421438267
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

2.37e-0625427365238
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

2.37e-0625426559257
Pubmed

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.

TPSAB1 TPSB2

2.37e-0625422187193
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

2.37e-06254227758680
Pubmed

Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.

TPSAB1 TPSB2

2.37e-0625428434231
Pubmed

Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.

C4A C4B

2.37e-06254219150565
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

2.37e-0625427391573
Pubmed

Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.

C4A C4B

2.37e-06254217506029
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

2.37e-06254222387014
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

2.37e-06254217971360
Pubmed

Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.

C4A C4B

2.37e-06254234299197
Pubmed

Assessment of complement C4 gene copy number using the paralog ratio test.

C4A C4B

2.37e-06254220506482
Pubmed

Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.

C4A C4B

2.37e-06254223715124
Pubmed

Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.

C4A C4B

2.37e-0625423464002
Pubmed

Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.

C4A C4B

2.37e-0625422993295
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

2.37e-06254229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

2.37e-06254217971229
Pubmed

Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.

C4A C4B

2.37e-06254212480675
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

2.37e-0625426881182
Pubmed

Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.

TPSAB1 TPSB2

2.37e-06254215567416
Pubmed

Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.

C4A C4B

2.37e-06254226800705
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

2.37e-06254223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

2.37e-06254223918728
Pubmed

Identification of the site of sulfation of the fourth component of human complement.

C4A C4B

2.37e-0625423944109
Pubmed

Murine complement C4 is not required for experimental autoimmune encephalomyelitis.

C4A C4B

2.37e-06254215390104
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

2.37e-0625423037333
Pubmed

Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.

TPSAB1 TPSB2

2.37e-06254210391906
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

2.37e-06254211726230
Pubmed

The human mast cell tryptase tetramer: a fascinating riddle solved by structure.

TPSAB1 TPSB2

2.37e-06254210708850
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

2.37e-0625424216347
Pubmed

Cloning and characterization of a second complementary DNA for human tryptase.

TPSAB1 TPSB2

2.37e-0625422203827
Pubmed

Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.

TPSAB1 TPSB2

2.37e-06254217449330
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

2.37e-06254217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

2.37e-06254221880985
Pubmed

Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.

C4A C4B

2.37e-0625421699796
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

2.37e-0625426978711
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

2.37e-0625426950384
Pubmed

Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.

C4A C4B

2.37e-0625422997024
Pubmed

YB-3 substitutes YB-1 in global mRNA binding.

YBX1 YBX3

2.37e-06254231944153
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

2.37e-06254235898513
Pubmed

Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.

C4A C4B

2.37e-06254233353966
Pubmed

Sequence comparison of alleles of the fourth component of complement (C4) and sex-limited protein (Slp).

C4A C4B

2.37e-0625423008092
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

2.37e-0625428660986
Pubmed

Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.

C4A C4B

2.37e-0625423624865
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

2.37e-06254228873507
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

2.37e-0625428428773
Pubmed

Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.

C4A C4B

2.37e-06254221857912
Pubmed

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.

TPSAB1 TPSB2

2.37e-06254231337736
Pubmed

The molecular basis for the difference in immune hemolysis activity of the Chido and Rodgers isotypes of human complement component C4.

C4A C4B

2.37e-0625426609966
Pubmed

Heterogeneity and linkage of equine C4 and steroid 21-hydroxylase genes.

C4A C4B

2.37e-0625422900855
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

2.37e-06254224638111
Pubmed

Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.

C4A C4B

2.37e-0625426208559
Pubmed

The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.

C4A C4B

2.37e-0625424514997
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

2.37e-062542276882
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

2.37e-06254221345967
Pubmed

The inheritance of susceptibility to the Gross leukemia virus in mice.

C4A C4B

2.37e-0625425919331
Pubmed

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.

C4A C4B

2.37e-0625426832377
Pubmed

An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.

C4A C4B

2.37e-0625423167981
Pubmed

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.

C4A C4B

2.37e-0625423794341
Pubmed

Complement and c4 null alleles in severe chronic adult periodontitis.

C4A C4B

2.37e-06254217257223
Pubmed

Three extra copies of a C4-related gene in H-2w7 mice are C4/Slp hybrid genes generated by multiple recombinational events.

C4A C4B

2.37e-0625422272665
Pubmed

Multiple C4/Slp genes distinguished by expression after transfection.

C4A C4B

2.37e-0625423023818
Pubmed

The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.

C4A C4B

2.37e-0625427545960
Pubmed

Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.

TPSAB1 TPSB2

2.37e-06254210898108
Pubmed

Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.

C4A C4B

2.37e-06254230041577
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

2.37e-0625422572548
Cytoband6p21.3

DXO C4A C4B GRM4

2.19e-042505446p21.3
Cytoband2q24.1

PKP4 GALNT13

4.68e-04275422q24.1
Cytoband2q33.3

CRYGC CRYGD

5.78e-04305422q33.3
CytobandEnsembl 112 genes in cytogenetic band chr9q34

GBGT1 FBXW5 SEC16A ST6GALNAC6

5.90e-04325544chr9q34
CytobandEnsembl 112 genes in cytogenetic band chr6p21

DXO C4A C4B GRM4

2.92e-03503544chr6p21
GeneFamilyY box binding proteins

YBX1 YBX3

1.36e-053392106
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

1.62e-0493921234
GeneFamilyBeta-gamma crystallins

CRYGC CRYGD

4.68e-04153921359
GeneFamilyPHD finger proteins|Lysine demethylases

KDM6A JMJD1C

1.21e-0324392485
GeneFamilyComplement system|Sushi domain containing

C4A C4B

2.73e-0336392492
GeneFamilyGlycosyltransferase family 6|Blood group antigens

C4A C4B

2.88e-0337392454
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRFN1 FGFR1 ADGRA3

5.01e-03161393593
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

MYO1G USP9Y

5.41e-0351392870
GeneFamilyRing finger proteins

RC3H1 TRIM17 TTC3

2.13e-0227539358
GeneFamilyOlfactory receptors, family 2

OR2T2 OR2L13

2.47e-02113392149
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC3 KDM6A

2.55e-02115392769
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FNDC1 SLITRK2 KCNT2 TENM3 C4A C4B

1.42e-0719754688a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FNDC1 SLITRK2 KCNT2 TENM3 C4A C4B

1.42e-071975462773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-basophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 CRYGD PNMT TPSB2 GALNT13

1.07e-06150545408b7c2c3a42f5455c8c26a83d9e366a1c8d5ecc
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 YBX1 PKP4 IRX3 N4BP3

1.56e-06162545465cb483f41023d6125ea147e16f404d8e8dc9bb
ToppCellControl-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

SLITRK2 KCNT2 C4A C4B ADGRA3

1.76e-0616654532ebaefa6c074b28193fff764ee7c2c0e9357e20
ToppCellControl-Epithelial-Mesothelial|Control / Disease state, Lineage and Cell class

SLITRK2 KCNT2 C4A C4B ADGRA3

1.76e-061665451ed3788257e14f097862b999f020bfe2a57de52b
ToppCellwk_20-22-Hematologic-Myeloid-Mast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 PNMT OR2L13 MACIR TPSB2

1.76e-06166545004ab6a1425d812c7ce572205875fd702d4a9659
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO1G TPSAB1 CRYGD PNMT TPSB2

2.15e-06173545b9dc42d629d13e63aada5ae49ba0cbb0952c5fe9
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO1G TPSAB1 CRYGD PNMT TPSB2

2.22e-0617454536080fa12497faa752ff07ae52cd3864053eafef
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPSAB1 CRYGD PNMT MACIR TPSB2

2.48e-06178545c6704fcd21a9d2fe45679a1d998f04213b3bf224
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 CRYGD PNMT MACIR TPSB2

2.84e-061835455ac38a2ce93c53f23a89faf287b81ea138560623
ToppCellCOPD-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

KCNT2 TENM3 C4A C4B FGFR1

3.24e-06188545159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 KCNT2 LOXL1 C4B FGFR1

3.59e-06192545a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 KCNT2 LOXL1 C4B FGFR1

3.59e-06192545eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 TENM3 LOXL1 C4B FGFR1

3.68e-06193545025836c5c5a711e477c326559e618e47cae42d11
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FNDC1 KCNT2 TENM3 LOXL1 FGFR1

3.68e-06193545051f61156b0e2e95292b2d8377faf3190b50f264
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast|World / Lineage, cell class and subclass

TPSAB1 CRYGD PNMT GBGT1 TPSB2

3.77e-06194545f054d78429364622d402ce1d9bf6ad13a1a1bf7e
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FNDC1 TENM3 LOXL1 DLX3 RIMS1

3.96e-0619654557df2a57b35be9851ac0b1e5731baa53052511f0
ToppCellBiopsy_IPF-Mesenchymal-Mesothelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

SLITRK2 KCNT2 TENM3 C4A C4B

4.37e-06200545553386523fd8f8f36617a0d81032224b7ddce442
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Thalamus / BrainAtlas - Mouse McCarroll V32

MYO1G TPSAB1 GBGT1 TPSB2

1.01e-05111544a1b7940c6fa0e5a58aa4798b604469d79f33fa44
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Thalamus / BrainAtlas - Mouse McCarroll V32

MYO1G TPSAB1 GBGT1 TPSB2

1.01e-05111544567e5ac2c78d45db207067f0f152bb24ed048c50
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Thalamus / BrainAtlas - Mouse McCarroll V32

MYO1G TPSAB1 GBGT1 TPSB2

1.01e-05111544d1ec8e8e9adb11511b4ef363cc6f99286e2cc842
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Thalamus / BrainAtlas - Mouse McCarroll V32

MYO1G TPSAB1 GBGT1 TPSB2

1.01e-05111544fd7aa25e83a0d762969e3966a658652da40c490e
ToppCellThalamus-Hematopoietic-MACROPHAGE|Thalamus / BrainAtlas - Mouse McCarroll V32

MYO1G TPSAB1 GBGT1 TPSB2

1.01e-05111544d48561078c387ac856c1c30e3d7a3e75ebde942e
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

FNDC1 KCNA5 TENM3 LOXL1

3.21e-05149544dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPSAB1 PNMT MACIR TPSB2

3.38e-05151544bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCellAdult-Immune-mast_cell-D122|Adult / Lineage, Cell type, age group and donor

INTS6L TPSAB1 PNMT TPSB2

3.75e-051555447c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCellAdult-Immune-mast_cell|Adult / Lineage, Cell type, age group and donor

INTS6L TPSAB1 PNMT TPSB2

4.35e-0516154444f5c0256b3ce264a6c7b62740f32dcd45ee052d
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

MAGEA4 TPSAB1 YBX1 TPSB2

4.56e-05163544be774c0ba38fa89a9c0076524cf05d593c6c6826
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INTS6L TPSAB1 MACIR TPSB2

4.78e-0516554437615622c736e43260c38016e7c9e565ac97a3e8
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INTS6L TPSAB1 MACIR TPSB2

4.78e-05165544640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INTS6L TPSAB1 MACIR TPSB2

4.78e-05165544f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCellfacs-Tongue-nan-24m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLITRK2 YBX1 C4B YBX3

5.01e-0516754473fdf4b81a45ec686d2929eaf641b434f70b7898
ToppCellfacs-Tongue-nan-24m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLITRK2 YBX1 C4B YBX3

5.01e-05167544c4157fb31b44fe7c44be4215dda8ae2d37cf49a8
ToppCellwk_20-22-Hematologic-Myeloid-Eosinophil|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 CRYGD PNMT TPSB2

5.49e-05171544fa6e856e62b82ec4972e0098e73f237cc611891f
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RLBP1 SLITRK2 KCNT2 TENM3

5.62e-051725448d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCellImmune-mast_cell|World / Lineage, Cell type, age group and donor

INTS6L TPSAB1 PNMT TPSB2

5.62e-051725446e8e0aac5a20dbc789bf8c6916833bb8709a411a
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO1G TPSAB1 CRYGD TPSB2

5.62e-051725442ab720a4c96073339a1f8b95ec7699682df98acf
ToppCellwk_15-18-Hematologic-Myeloid-Eosinophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 PNMT MACIR TPSB2

5.75e-05173544a85cead231e03945fabbc7762540ad21fe4299df
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

INTS6L TPSAB1 PNMT TPSB2

6.14e-05176544473c45a381ca109207d66ed1635668b391ea0e1f
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLITRK2 C4A C4B FGFR1

6.28e-051775440912a291cff32a4ff8a2d7680ed1a1cd867fb90f
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TENM3 TRIM17 ADAMTS18 DLX3

6.42e-05178544e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCellCOVID-19_Mild-Hematopoietic_SC-HSPC|COVID-19_Mild / Disease group, lineage and cell class

TPSAB1 CRYGD PNMT TPSB2

6.56e-0517954419fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCLAF3 KCNA5 PKP4 IRX3

6.56e-0517954408cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellCOVID-19_Mild-Hematopoietic_SC|COVID-19_Mild / Disease group, lineage and cell class

TPSAB1 CRYGD PNMT TPSB2

6.56e-0517954450a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Undetermined|normal_Pleural_Fluid / Location, Cell class and cell subclass

MAGEA4 TPSAB1 YBX1 TPSB2

7.00e-05182544bfab19f855c4a595f7d652d43f159f0fcd8d56d1
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TENM3 TRIM17 ADAMTS18 DLX3

7.00e-05182544193cb2df3d7ea4cb9a11390b92955e7d9b0a053a
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cells|lymph-node_spleen / Manually curated celltypes from each tissue

TPSAB1 CRYGD PNMT TPSB2

7.30e-05184544ed266bd2d12f86e8786473e64fbcd58319cd4c2a
ToppCell3'_v3-lymph-node_spleen-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

TPSAB1 CRYGD PNMT TPSB2

7.30e-0518454483675c7a083c52fb74dc8b9d35df0ef69715f707
ToppCellCOVID-19_Moderate-HSPC|World / disease group, cell group and cell class

TPSAB1 CRYGD PNMT TPSB2

7.30e-05184544ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

TPSAB1 PNMT MACIR TPSB2

7.30e-05184544bc394eaa441fcaffcc4ace062741bca1da229324
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNDC1 KCNT2 TENM3 ADGRA3

7.45e-051855448ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Mast_cells|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

TPSAB1 PNMT MACIR TPSB2

7.45e-05185544a6e5328801c233a44153420e2cdae644b253f540
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

KCNT2 C4A C4B ADGRA3

7.45e-0518554423579988036fc1925992c31919750f9b3fe9f790
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNDC1 KCNT2 TENM3 ADGRA3

7.45e-05185544b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCellCOVID-19_Moderate-HSPC|COVID-19_Moderate / disease group, cell group and cell class

TPSAB1 CRYGD PNMT TPSB2

7.45e-05185544cacc6ab5f26f6c803894567fb838ea06eaa7efe5
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RLBP1 ADAMTS18 IRX3 ADGRA3

7.61e-0518654441e03be964044dae690d566bd078dab3d8045eba
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMS1 ST6GALNAC6 TTC3 GALNT13

7.61e-05186544d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PNMT MACIR TPSB2

7.61e-05186544f690e26b2ed024bd8ede494b8e9a00976fdc9734
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 LOXL1 C4B FGFR1

7.77e-051875447beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMS1 GRM4 TTC3 GALNT13

7.77e-051875441b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 KCNT2 LOXL1 FGFR1

7.77e-05187544ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 LOXL1 C4B FGFR1

7.77e-051875442c145e9d11424939dd99012a8cedf5d998b966e9
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 YBX1 PKP4 N4BP3

7.93e-051885448a87daf2851d9404df7c36f279db599574b47c69
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 YBX1 PKP4 N4BP3

7.93e-051885440f426cca2ad7671fed9c6d2aa09f6a8627a518cd
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM3 PKP4 SEC16A TTC3

7.93e-05188544a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

FNDC1 KCNT2 TENM3 ADGRA3

7.93e-051885447b1e3f8a941eaa68e89c562129a92314642eec66
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RLBP1 FNDC1 SLITRK2 GALNT13

7.93e-05188544006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RLBP1 FNDC1 SLITRK2 GALNT13

7.93e-05188544d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 YBX1 PKP4 N4BP3

7.93e-05188544aec7485f1a9412bd3a62b70c801cb7f8dcca232d
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

KCNT2 C4A C4B ADGRA3

8.10e-0518954479bb2593ad5d17f94b17972884241f03a0f43770
ToppCellfacs-Skin-nan-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 KCNT2 LOXL1 ST6GALNAC6

8.10e-0518954429287525120be2953b76881ba3cfc4379c265e7a
ToppCellfacs-Skin-nan-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 KCNT2 LOXL1 ST6GALNAC6

8.10e-051895447150dad9a92a715487c2d8130fa01b752ea69663
ToppCellfacs-Skin-nan-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 KCNT2 LOXL1 ST6GALNAC6

8.10e-051895446e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCellfacs-GAT-Fat-24m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 PKP4 IRX3 N4BP3

8.26e-05190544da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCellfacs-GAT-Fat-24m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 PKP4 IRX3 N4BP3

8.26e-05190544e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 LOXL1 C4B FGFR1

8.26e-0519054497772e69e6f51ebffbb5433ca7b40f1048723220
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 PNMT MACIR TPSB2

8.26e-051905447774dc0b4ae7d5920b516800f3b90cbf831f8d3d
ToppCellfacs-GAT-Fat-24m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 PKP4 IRX3 N4BP3

8.26e-051905443395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 YBX1 PKP4 N4BP3

8.26e-05190544f98e2d45fab7d9e16629d7f13cc2ccfb939ef4dd
ToppCelldroplet-Lung-nan-18m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 LOXL1 C4B FGFR1

8.26e-0519054472c2b824acdc43139e6635785df3ed3feb58ec46
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 LOXL1 C4B FGFR1

8.43e-051915441efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 YBX1 PKP4 N4BP3

8.43e-051915445020fe6c3452e7fab57847f5043d28ebbc5aa381
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.43e-051915442b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 KCNT2 TENM3 LOXL1

8.43e-0519154424dc77ee8de01b42559f92721655f4281b114e17
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FNDC1 KCNT2 LOXL1 FGFR1

8.43e-051915449f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 LOXL1 C4B FGFR1

8.43e-051915449214655dca96d766737c9f30b624d7fe7050342e
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.60e-0519254432acd89617934016cd135d2cc797e8e79ae1b37f
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 YBX1 PKP4 N4BP3

8.60e-0519254424d28e28a5c54ca7770f7e5ad7f4d00039e0aaf9
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.60e-05192544c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 LOXL1 C4B FGFR1

8.60e-051925445e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.60e-051925447a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FNDC1 LOXL1 C4B FGFR1

8.60e-05192544cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.60e-05192544f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.60e-051925440e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FNDC1 LOXL1 C4B FGFR1

8.60e-0519254429bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.60e-05192544011634a24b0c61d9b463fe755502edbc5cd70b7a
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.60e-051925447b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellfacs-Trachea-24m-Mesenchymal|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 LOXL1 C4B FGFR1

8.60e-05192544e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 LOXL1 C4B FGFR1

8.60e-051925442d9e2262f1342fe17735f21f733c029d1275e955
DrugT1 p

CRYGC CRYGD PPAT KDM6A

6.50e-0651544CID000657023
Drugthymidine glycol monophosphate

TPSAB1 TPSB2

1.65e-053542CID000165415
Drug2-aminothiophenol

C4A C4B

1.65e-053542ctd:C005464
DrugAC1NRA23

TPSAB1 CSN3 C4A TPSB2

2.72e-0573544CID005287657
DrugBrunfelsamidine

TPSAB1 TPSB2

3.30e-054542CID005281683
Diseasecataract 2 multiple types (implicated_via_orthology)

CRYGC CRYGD

2.93e-062512DOID:0110235 (implicated_via_orthology)
DiseaseCATARACT, AUTOSOMAL DOMINANT

CRYGC CRYGD

1.75e-054512C1858679
Diseasetaste liking measurement

ARID1B KCNA5 OR10G3 PKP4 C4B MACIR

5.43e-05388516EFO_0010155
Diseasesystemic lupus erythematosus (implicated_via_orthology)

RC3H1 C4A C4B

5.72e-0543513DOID:9074 (implicated_via_orthology)
DiseaseCATARACT, COPPOCK-LIKE

CRYGC CRYGD

1.05e-049512C1852438
DiseaseCataract, Pulverulent

CRYGC CRYGD

1.05e-049512C1833118
DiseaseCataract microcornea syndrome

CRYGC CRYGD

1.05e-049512C1861829
Diseasetryptase beta-2 measurement

TPSAB1 TPSB2

1.05e-049512EFO_0008306
DiseaseNuclear cataract

CRYGC CRYGD

4.40e-0418512C0392557
DiseaseNuclear non-senile cataract

CRYGC CRYGD

4.40e-0418512C1112705
DiseaseMalignant neoplasm of breast

MAGEA4 ARID1B KCNA5 KCNT2 YBX1 FGFR1 TTC3 MACIR

4.76e-041074518C0006142
Diseaseurticaria

TPSAB1 TPSB2

5.46e-0420512EFO_0005531
Diseasetotal cortical area measurement

KCNA5 LOXL1 ADAMTS18

5.84e-0494513EFO_0008381
DiseasePseudoaphakia

CRYGC CRYGD

7.89e-0424512C0524524
DiseaseLens Opacities

CRYGC CRYGD

7.89e-0424512C1510497
DiseaseComplement deficiency disease

C4A C4B

1.49e-0333512C0272242
Diseasejoint hypermobility measurement

FNDC1 LOXL1

1.49e-0333512EFO_0007905

Protein segments in the cluster

PeptideGeneStartEntry
ATYAEPYRPIQYRVQ

PKP4

476

Q99569
PYRPIQYRVQECNYN

PKP4

481

Q99569
DQPIYNPGQRVRYRV

C4B

146

P0C0L5
RRAYLAYRERQYNPP

ADGRA3

1221

Q8IWK6
APGRYDIYQYQLRND

GRM4

471

Q14833
RRPIQGQYPYPYSRE

ARID1B

1486

Q8NFD5
QRINERPPYYLGRDY

DUS3L

596

Q96G46
TLCRYRDYRNPPDYN

ANO9

676

A1A5B4
SYRQYGAYREQPLPA

DLX3

91

O60479
YQRSFNRPERLYAPG

ADAMTS18

821

Q8TE60
PESRERYQQIESYYP

RC3H1

706

Q5TC82
PQTYRNAYDIPRRGL

INTS6L

506

Q5JSJ4
YDRYVAVCNPLRYPL

OR2T2

121

Q6IF00
YLEYRQVPGSNPARY

MAGEA4

256

P43358
ARPRPQQRYSFDGDY

LRFN1

696

Q9P244
PYSLNGYRVRVYRQD

JMJD1C

186

Q15652
YEANVPVYRFIQRPG

KDM6A

1201

O15550
SAGVIYPYQPRARYE

LOXL1

221

Q08397
YRYYQVARDVPRHPA

FBXW5

51

Q969U6
SRYYQPYEIPAVNGR

MACIR

111

Q96GV9
GLYNFIVPLRAYYRP

KCNT2

731

Q6UVM3
YDRYLAICQPLRYPV

OR10G3

121

Q8NGC4
NFDLRDGYPDRYQPR

DXO

81

O77932
YQTRYRSDPNLARYP

RIMS1

351

Q86UR5
NIYPDSQIPRRYYSL

GALNT13

416

Q8IUC8
GRQYLLMPGDYRRYQ

CRYGD

141

P07320
LYYYQSGGRLRRPVN

KCNA5

176

P22460
PRIPSRGNIYYQSYE

BCLAF3

61

A2AJT9
YYAVPRQQFPYERRR

GBGT1

231

Q8N5D6
EYLQARRPPGLEYCY

FGFR1

571

P11362
QGYYRQYRQEPVRFG

FNDC1

1856

Q4ZHG4
PYYGTNLYQRRPAIA

CSN3

56

P07498
YERPNYQGQQYLLRR

CRYGC

46

P07315
YQGQQYLLRRGEYPD

CRYGC

51

P07315
QVGYRYNPRPRLDRS

INPP5F

336

Q9Y2H2
DQPIYNPGQRVRYRV

C4A

146

P0C0L4
LGYQYIRPLYPSERP

IRX3

6

P78415
YAPFVYTYLRPRNLR

OR2L13

251

Q8N349
PNRPGIYTRVTYYLD

TPSAB1

251

Q15661
PNRPGIYTRVTYYLD

TPSB2

251

P20231
RRLYLNGNYLEVLYP

SLITRK2

426

Q9H156
SQRPRLQRMPYHYYE

ST6GALNAC6

271

Q969X2
PAQPGFERLRRQYLY

CNGA4

206

Q8IV77
EPRAYLRNNYAPPRG

PNMT

31

P11086
PQYRPQYRQRRFPPY

YBX3

226

P16989
NQPSVRRGYRRPYNY

YBX3

321

P16989
YYMRRPYGRRPQYSN

YBX1

196

P67809
ASAYAQNYRYPEPER

SEC16A

1206

O15027
RDVIYAVRDPYGNRP

PPAT

191

Q06203
RAIEYRPENYLLYGN

TTC3

256

P53804
RSIGYYRNIYNPPES

TENM3

1906

Q9P273
YELLRGYVNFRLQYP

RLBP1

111

P12271
ELERRPYTGNPQYSY

USP9Y

2426

O00507
RPPYYGYVKRATNRE

SPRTN

176

Q9H040
PYLLLYESRQRRYLG

TRIM17

306

Q9Y577
YQGRELYERPPHLYA

MYO1G

66

B0I1T2
PRNEPADYATLYYRE

N4BP3

76

O15049