Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainEGF_1

FAT2 EREG FBLN2 ZAN ADAM15 LRP5 LTBP1 LTBP3 USH2A NOTCH3

5.10e-072559210PS00022
DomainEGF

FAT2 EREG FBLN2 ZAN ADAM15 LRP5 LTBP1 LTBP3 NOTCH3

2.38e-06235929SM00181
DomainEGF_3

FAT2 EREG FBLN2 ZAN ADAM15 LRP5 LTBP1 LTBP3 NOTCH3

2.38e-06235929PS50026
DomainEGF-like_dom

FAT2 EREG FBLN2 ZAN ADAM15 LRP5 LTBP1 LTBP3 NOTCH3

3.82e-06249929IPR000742
DomainEGF-like_CS

FAT2 EREG FBLN2 ZAN ADAM15 LRP5 LTBP1 LTBP3 NOTCH3

5.60e-06261929IPR013032
DomainEGF_2

FAT2 EREG FBLN2 ZAN ADAM15 LRP5 LTBP1 LTBP3 NOTCH3

6.33e-06265929PS01186
Domain-

FSTL3 LTBP1 LTBP3

6.36e-0689233.90.290.10
DomainTB_dom

FSTL3 LTBP1 LTBP3

9.51e-069923IPR017878
DomainTB

FSTL3 LTBP1 LTBP3

9.51e-069923PS51364
DomainEGF-like_Ca-bd_dom

FAT2 FBLN2 LRP5 LTBP1 LTBP3 NOTCH3

3.39e-05124926IPR001881
DomainEGF

FAT2 EREG ZAN LRP5 LTBP1 NOTCH3

3.71e-05126926PF00008
DomainEGF_CA

FBLN2 LRP5 LTBP1 LTBP3 NOTCH3

1.29e-0499925PS01187
DomaincEGF

FBLN2 LTBP1 LTBP3

2.77e-0426923PF12662
DomaincEGF

FBLN2 LTBP1 LTBP3

2.77e-0426923IPR026823
DomainEGF_CA

FAT2 FBLN2 LTBP1 LTBP3 NOTCH3

3.42e-04122925SM00179
DomainTB

LTBP1 LTBP3

4.96e-047922PF00683
Domainzf-TRAF

TRAF4 PDZRN3

6.59e-048922PF02176
DomainEGF_CA

FBLN2 LTBP1 LTBP3 NOTCH3

8.60e-0486924PF07645
DomainGrowth_fac_rcpt_

FBLN2 LTBP1 LTBP3 FBXL19 NOTCH3

1.05e-03156925IPR009030
DomainEGF_Ca-bd_CS

FBLN2 LTBP1 LTBP3 NOTCH3

1.35e-0397924IPR018097
DomainASX_HYDROXYL

FBLN2 LTBP1 LTBP3 NOTCH3

1.51e-03100924PS00010
DomainZnf_TRAF

TRAF4 PDZRN3

1.53e-0312922IPR001293
DomainZF_TRAF

TRAF4 PDZRN3

1.81e-0313922PS50145
DomainEGF-type_Asp/Asn_hydroxyl_site

FBLN2 LTBP1 LTBP3 NOTCH3

1.87e-03106924IPR000152
Domain-

TRAF4 PDZRN3

2.10e-03149223.90.890.10
DomainSIAH-type

TRAF4 PDZRN3

2.75e-0316922IPR013323
DomainIntegrin_alpha-2

ITGA11 ITGA5

3.49e-0318922IPR013649
DomainINTEGRIN_ALPHA

ITGA11 ITGA5

3.49e-0318922PS00242
DomainIntegrin_alpha2

ITGA11 ITGA5

3.49e-0318922PF08441
DomainIntegrin_alpha

ITGA11 ITGA5

3.49e-0318922IPR000413
DomainInt_alpha

ITGA11 ITGA5

3.89e-0319922SM00191
DomainInt_alpha_beta-p

ITGA11 ITGA5

3.89e-0319922IPR013519
DomainBRCT

MCPH1 BARD1

3.89e-0319922PF00533
DomainAnk_2

CTTNBP2 ASB10 BARD1 NOTCH3 AGAP2

4.22e-03215925PF12796
DomainDAPIN

NLRP14 NLRP3

5.20e-0322922PS50824
DomainFG_GAP

ITGA11 ITGA5

5.20e-0322922PS51470
DomainPYRIN

NLRP14 NLRP3

5.20e-0322922SM01289
DomainPYRIN

NLRP14 NLRP3

5.20e-0322922PF02758
DomainDAPIN

NLRP14 NLRP3

5.20e-0322922IPR004020
DomainBRCT

MCPH1 BARD1

5.20e-0322922SM00292
DomainAnk

CTTNBP2 ASB10 BARD1 NOTCH3 AGAP2

5.40e-03228925PF00023
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBLN2 LTBP1 LTBP3 ITGA5

3.80e-0539694MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBLN2 LTBP1 LTBP3 ITGA5

6.16e-0544694M26969
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 MST1R TRAF4 TRIO PI4KA POLE OSBPL5 SHC1 LRP5 DDX56 HMGXB3 LTBP3 FBXL19 ITGA5 PUM1 ESPL1 ULK2 TTC38 PLEKHH3

1.12e-101105941935748872
Pubmed

Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

UQCRFS1 UQCRFS1P1

7.23e-06294223415911
Pubmed

A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice.

UQCRFS1 UQCRFS1P1

7.23e-06294222028811
Pubmed

Assignment of the gene (UQCRFS1) for the Rieske iron-sulfur protein subunit of the mitochondrial cytochrome bc1 complex to the 22q13 and 19q12-q13.1 regions of the human genome.

UQCRFS1 UQCRFS1P1

7.23e-0629428088805
Pubmed

Cells lacking Rieske iron-sulfur protein have a reactive oxygen species-associated decrease in respiratory complexes I and IV.

UQCRFS1 UQCRFS1P1

7.23e-06294222106410
Pubmed

A 3' UTR modification of the mitochondrial rieske iron sulfur protein in mice produces a specific skin pigmentation phenotype.

UQCRFS1 UQCRFS1P1

7.23e-06294218401429
Pubmed

p66Shc/Notch-3 interplay controls self-renewal and hypoxia survival in human stem/progenitor cells of the mammary gland expanded in vitro as mammospheres.

SHC1 NOTCH3

7.23e-06294217158237
Pubmed

Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits.

LTBP1 NOTCH3

7.23e-06294225190493
Pubmed

Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution.

RTEL1 POLDIP3

7.23e-06294232561545
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MYH7 NCAPG GTF3C1 PI4KA POLE UQCRFS1 NOL9 PUM1 STAG2 NOTCH3 NUP205

2.05e-05857941125609649
Pubmed

Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation.

UQCRFS1 UQCRFS1P1

2.16e-05394223328522
Pubmed

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair.

UQCRFS1 UQCRFS1P1

2.16e-05394230595481
Pubmed

Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3).

LTBP1 LTBP3

2.16e-0539427730318
Pubmed

The NLRP3 Inflammasome Is a Pathogen Sensor for Invasive Entamoeba histolytica via Activation of α5β1 Integrin at the Macrophage-Amebae Intercellular Junction.

ITGA5 NLRP3

2.16e-05394225955828
Pubmed

TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III.

UQCRFS1 UQCRFS1P1

2.16e-05394228673544
Pubmed

Oxygen regulation of breathing is abolished in mitochondrial complex III-deficient arterial chemoreceptors.

UQCRFS1 UQCRFS1P1

2.16e-05394236122208
Pubmed

A defect in the mitochondrial complex III, but not complex IV, triggers early ROS-dependent damage in defined brain regions.

UQCRFS1 UQCRFS1P1

2.16e-05394222914734
Pubmed

Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells.

LTBP1 LTBP3

2.16e-05394218672106
Pubmed

Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.

LTBP1 LTBP3

2.16e-05394210743502
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

ITGA11 ITGA5 CSMD3

2.84e-052294335245678
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CYP26B1 GTF3C1 MCPH1 PI4KA KIF21A PIWIL2 ARHGEF17 ATXN1L DNAH14 NUP205

3.10e-05736941029676528
Pubmed

The role of annexin A1 in the modulation of the NLRP3 inflammasome.

FPR2 NLRP3

4.32e-05494232107769
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP1 LTBP3

4.32e-05494215611103
Pubmed

Compensatory elevation of voluntary activity in mouse mutants with impaired mitochondrial energy metabolism.

UQCRFS1 UQCRFS1P1

4.32e-05494225413331
Pubmed

Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization.

FPR2 NLRP3

4.32e-05494234595678
Pubmed

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy.

SHC1 NLRP3

4.32e-05494225075770
Pubmed

The mitochondrial respiratory chain is essential for haematopoietic stem cell function.

UQCRFS1 UQCRFS1P1

4.32e-05494228504706
Pubmed

Integrin-mediated first signal for inflammasome activation in intestinal epithelial cells.

ITGA5 NLRP3

4.32e-05494224965773
Pubmed

Mutations in TTC19 cause mitochondrial complex III deficiency and neurological impairment in humans and flies.

UQCRFS1 UQCRFS1P1

4.32e-05494221278747
Pubmed

Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart.

LTBP1 LTBP3

4.32e-0549429008713
Pubmed

The latent transforming growth factor beta binding protein (LTBP) family.

LTBP1 LTBP3

4.32e-05494211104663
Pubmed

Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.

LTBP1 LTBP3

4.32e-05494216157329
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NCAPG ADAM15 PI4KA POLE MTR SLC35B2 PUM1 ESPL1 STAG2 PCK2 NUP205

4.84e-05942941131073040
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

MYH7 FAT2 RTEL1 MAP3K21 ESPL1

5.99e-0515294534299191
Pubmed

Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm.

LTBP1 LTBP3

7.19e-05594219897194
Pubmed

TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis.

TRAF4 SHC1

7.19e-05594229715200
Pubmed

CXCL5 promotes lipotoxicity of hepatocytes through upregulating NLRP3/Caspase-1/IL-1β signaling in Kupffer cells and exacerbates nonalcoholic steatohepatitis in mice.

CXCL5 NLRP3

7.19e-05594237573690
Pubmed

Mitochondrial complex III is essential for suppressive function of regulatory T cells.

UQCRFS1 UQCRFS1P1

7.19e-05594230626970
Pubmed

The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells.

MST1R CXCL5

7.19e-05594219838218
Pubmed

A common mechanism for recruiting the Rrm3 and RTEL1 accessory helicases to the eukaryotic replisome.

RTEL1 POLE

7.19e-05594239039288
Pubmed

Characterization of initial key steps of IL-17 receptor B oncogenic signaling for targeted therapy of pancreatic cancer.

MAP3K21 IL17RB

7.19e-05594233658352
Pubmed

Endothelial Cyp26b1 restrains murine heart valve growth during development.

FBLN2 CYP26B1 ADAM15 LRP5 ITGA5

8.34e-0516394535364055
Pubmed

Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.

ADAM15 KIF21A PCK2

8.96e-053294331815296
Pubmed

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.

NCAPG ESPL1 PCK2 PDLIM4

9.38e-058794433798452
Pubmed

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.

FBLN2 LTBP1

1.08e-04694219349279
Pubmed

Tetraspanin CD81 is linked to ERK/MAPKinase signaling by Shc in liver tumor cells.

PI4KA SHC1

1.08e-04694214676841
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

MYH7 FBLN2 NOTCH3

1.18e-043594321252157
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NCAPG GTF3C1 TRIO POLDIP3 PI4KA POLE MTR DDX56 NOL9 TDRD6 PUM1 STAG2 NUP205

1.19e-041425941330948266
Pubmed

Role of multiple beta1 integrins in cell adhesion to the disintegrin domains of ADAMs 2 and 3.

ADAM15 ITGA5

1.50e-04794214516789
Pubmed

Murine lipid phosphate phosphohydrolase-3 acts as a cell-associated integrin ligand.

SHC1 ITGA5

1.50e-04794216099422
Pubmed

Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria.

UQCRFS1 UQCRFS1P1

1.50e-04794229228266
Pubmed

Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.

LTBP1 LTBP3

1.50e-04794210930463
Pubmed

Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.

MST1R SHC1

1.50e-04794214982882
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

GTF3C1 MCPH1 TRIO RTEL1 RIN2 OSBPL5 BARD1 ZFHX2 LRP5 DDX56 STAG2 DNAH14 NOTCH3

1.84e-041489941328611215
Pubmed

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

HMGXB3 ESPL1 AGAP2

1.89e-04419438724849
Pubmed

Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.

LTBP1 LTBP3

2.00e-04894227339457
Pubmed

STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family.

MST1R SHC1

2.00e-0489428918464
Pubmed

Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression.

PIWIL2 TDRD6

2.00e-04894228254886
Pubmed

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.

PIWIL2 TDRD6

3.21e-041094219584108
Pubmed

IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway.

RTEL1 POLE

3.21e-041094223585563
Pubmed

Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosa.

IL17RB NLRP3

3.21e-041094224663677
Pubmed

IL-1β suppresses innate IL-25 and IL-33 production and maintains helminth chronicity.

IL17RB NLRP3

3.91e-041194223935505
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

GTF3C1 POLDIP3 POLE DDX56 NOL9 PUM1 STAG2 NUP205

3.99e-0465394822586326
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

MST1R ITGA11 GTF3C1 FSTL3 ADAM15 LRP5 SLC35B2 LTBP1 LTBP3 ITGA5 NOTCH3

4.00e-041201941135696571
Pubmed

NODs: intracellular proteins involved in inflammation and apoptosis.

NLRP14 NLRP3

4.69e-041294212766759
Pubmed

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.

UQCRFS1 UQCRFS1P1

5.53e-041394217376863
Pubmed

Characterization of the piRNA complex from rat testes.

RAD54B SHC1 PHF7 OTUD7B

5.79e-0414094416778019
Pubmed

Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro.

CYP26B1 RXRG

6.44e-041494218561907
Pubmed

Retinoic acid induces prostatic bud formation.

CYP26B1 RXRG

6.44e-041494218393306
Pubmed

The genetics of NOD-like receptors in Crohn's disease.

NLRP14 NLRP3

6.44e-041494220403135
Pubmed

NALPs: a novel protein family involved in inflammation.

NLRP14 NLRP3

6.44e-041494212563287
Pubmed

Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina.

RXRG NOTCH3

6.44e-041494225100656
Pubmed

Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling.

LTBP1 LTBP3

7.42e-041594217804598
Pubmed

Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria.

UQCRFS1 UQCRFS1P1

7.42e-041594216120479
Pubmed

CRL4-DCAF8L2 E3 ligase promotes ubiquitination and degradation of BARD1.

BARD1 IL17RB

7.42e-041594235487060
Pubmed

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing.

PIWIL2 TDRD6

7.42e-041594225762440
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

GTF3C1 PI4KA DDX56 STAG2

7.50e-0415094430154076
Pubmed

Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta.

CYP26B1 RXRG

8.46e-041694225577283
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TRIO POLDIP3 ADAM15 MTR PUM1 ESPL1 TRIP4 PDZRN3

8.49e-0473394834672954
Pubmed

Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression.

PIWIL2 TDRD6

9.57e-041794219345099
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

GTF3C1 POLDIP3 POLE BARD1 DDX56 NOL9 ESPL1 NUP205

1.06e-0375994835915203
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

TRIO POLDIP3 SHC1 LTBP1 TDRD6

1.06e-0328494529459677
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NCAPG GTF3C1 POLDIP3 PI4KA POLE KIF21A DDX56 NOL9 PUM1 PCK2 NUP205

1.07e-031353941129467282
Pubmed

Chromosomal mapping of Adam9, Adam15 and Adam21.

ADAM15 RXRG

1.08e-031894210842103
Pubmed

The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map.

OR2C1 CYP26B1

1.08e-031894226446231
Pubmed

Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly.

MCPH1 PCK2

1.33e-032094232294449
Pubmed

Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning.

CYP26B1 RXRG

1.33e-032094219605690
Pubmed

Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions.

POLDIP3 UQCRFS1 UQCRFS1P1 AGAP2

1.36e-0317694418614564
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

CILP2 ADAM15 LTBP1 LTBP3 ITGA5 PUM1 NUP205

1.39e-0361394722268729
Pubmed

Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.

MACROD2 LTBP3

1.47e-032194220708005
Pubmed

The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex.

TRAF4 PHF7

1.47e-032194225590999
Pubmed

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.

MYH7 NOTCH3

1.61e-032294236877136
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

PTP4A2 LRRN2 C4BPB NOL9 PUM1 MAP3K21 USH2A RXRG NLRP3

1.91e-03103194916710414
Pubmed

Neural crest cell-autonomous roles of fibronectin in cardiovascular development.

ITGA5 NOTCH3

1.92e-032494226552887
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

TRAF4 BARD1 DDX56 LTBP1 TRIP4 OTUD7B

1.98e-0348194628190767
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

KIF13B POLDIP3 MACROD2 TDRD6

2.05e-0319794420811636
Pubmed

Gse1, a component of the CoREST complex, is required for placenta development in the mouse.

ISLR2 ITGA5

2.08e-032594237019373
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

TCAF2 CTTNBP2 MCPH1 PHF7 NUP205

2.08e-0333194519490893
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

POLDIP3 DDX56 NOL9 MEAK7 NUP205

2.11e-0333294525693804
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PTP4A2 NCAPG TRIO PI4KA SHC1 LTBP1 ITGA5 PUM1 RBM20

2.15e-03104994927880917
InteractionTOP3B interactions

VWA5B2 MST1R TRAF4 TRIO RTEL1 POLDIP3 PI4KA POLE OSBPL5 SHC1 LRP5 DDX56 HMGXB3 LTBP3 FBXL19 ITGA5 PUM1 ESPL1 ULK2 TTC38 PLEKHH3

1.80e-0614709121int:TOP3B
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP1 LTBP3

9.34e-054722628
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

NCAPG MCPH1 POLE RAD54B BARD1 PIWIL2 ESPL1 NUP205

1.52e-05258918gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#4_top-relative-expression-ranked_1000

MYH7 MACROD2 HIF3A TRIP4

5.32e-0548914gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k4
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

ISLR2 ITGA11 ASB10 LTBP1 ARHGEF17 NOTCH3 PLEKHH3

2.28e-07200947b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCellP15-Epithelial-epithelial_progenitor_cell-epi_progenitor|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH7 FAT2 RTEL1 KIF21A LTBP3 MAP3K21

1.12e-06159946a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ISLR2 ITGA11 MACROD2 RBM20 PDZRN3 NOTCH3

1.70e-061719464ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

ITGA11 LTBP1 ITGA5 RBM20 PDZRN3 NOTCH3

2.29e-06180946d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBLN2 CTTNBP2 CYP26B1 ADAM15 LTBP1 ITGA5

3.04e-06189946c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellfacs-MAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 FBLN2 CYP26B1 FSTL3 LRRN2 PDLIM4

3.23e-06191946b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

ITGA11 LTBP1 ARHGEF17 RBM20 PDZRN3 NOTCH3

3.23e-06191946fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA11 LTBP1 ITGA5 RBM20 PDZRN3 NOTCH3

3.86e-06197946bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHC1 DDX56 LTBP1 LTBP3 ARHGEF17 PDLIM4

3.97e-06198946399760b6b6fef8639ded53b14f251b9fce600e81
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FSTL3 LRRN2 LTBP1 LTBP3 ARHGEF17 CSMD3

4.09e-06199946fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHC1 DDX56 LTBP1 LTBP3 ITGA5 PDLIM4

4.09e-0619994685bb28369e0568b7b3bda095722102fc793f60ef
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ISLR2 ITGA11 LTBP1 ARHGEF17 NOTCH3 PLEKHH3

4.21e-062009469169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FBLN2 CTTNBP2 CYP26B1 ADAM15 LTBP1 RXRG

4.21e-06200946b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ISLR2 ARHGEF17 RXRG NOTCH3 ZNF697

1.46e-051469452ac9b487a7991fdc15444aeb93533030e09825bb
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-3|TCGA-Stomach / Sample_Type by Project: Shred V9

ISLR2 ITGA11 CYP26B1 ITGA5 NLRP3

1.56e-05148945c95a732163050cfb5d604c2a4c9eb1afa9f19a95
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

ITGA11 EREG FSTL3 LTBP1 NOTCH3

1.61e-05149945dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GTF3C1 KIF21A OSBPL5 TTC38 AGAP2

2.56e-0516494584a1808bc6f501218ac2a5a05eb188a07ccd3890
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPG POLE BARD1 IL17RB NLRP3

2.79e-05167945859dfe0764cb69de27e79e1c1aa65f9d538f79ea
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

CILP2 FBLN2 ITGA5 PDZRN3 AGAP2

2.87e-05168945aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA11 FBLN2 TRIO LTBP1 OVCH1

3.21e-05172945e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

ISLR2 LTBP1 ITGA5 RBM20 PDZRN3

3.30e-05173945a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ITGA11 LTBP1 RBM20 PDZRN3 NOTCH3

3.30e-051739455416b092321c7d9b63f0418c60f2402a138355bf
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Striatum / BrainAtlas - Mouse McCarroll V32

NCAPG POLE RAD54B BARD1 ESPL1

3.58e-05176945d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1|Striatum / BrainAtlas - Mouse McCarroll V32

NCAPG POLE RAD54B BARD1 ESPL1

3.58e-05176945a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CTTNBP2 LTBP1 LTBP3 HIF3A PDZRN3

3.68e-05177945b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 LTBP1 ARHGEF17 RBM20 NOTCH3

3.68e-05177945a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 LTBP1 ARHGEF17 RBM20 NOTCH3

3.68e-051779453645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF4 NCAPG RAD54B MTR NLRP3

3.89e-051799459dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA11 FBLN2 FSTL3 LRRN2 LTBP3

3.99e-0518094539ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

ISLR2 ITGA11 FSTL3 LTBP1 PDZRN3

4.10e-05181945bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellPericytes-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ITGA11 CTTNBP2 LTBP1 PDZRN3 NOTCH3

4.10e-05181945ff445a8e56522e57e27405184d123cf905caf8cc
ToppCellwk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ITGA11 CILP2 FBLN2 LTBP1 PCK2

4.20e-051829450e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CILP2 FBLN2 FSTL3 LTBP1 PDZRN3

4.32e-051839452beb5414958d38a5341870d55229f3b1707e76bf
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

ITGA11 FBLN2 LTBP1 HIF3A PDZRN3

4.43e-051849452b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

ITGA11 FBLN2 CTTNBP2 LTBP1 PDZRN3

4.54e-05185945fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA11 MACROD2 LTBP1 RBM20 NOTCH3

4.66e-051869454780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN2 CYP26B1 ADAM15 LTBP1 ITGA5

4.91e-051889455eb107122064f0a99dfd445cc87d3766f7257216
ToppCellfacs-Heart-LV-3m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7 ASB10 MTR RBM20 RXRG

4.91e-0518894540ce7125fca6f6b6b5cc1637c87d43c29b08f4f1
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

ISLR2 ITGA11 TRIO LTBP1 NOTCH3

4.91e-0518894514bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

KIF13B ISLR2 CILP2 LTBP3 NLRP3

4.91e-05188945c90669b51e1902fe7726555290c91c92a911df83
ToppCellfacs-Heart-LV-3m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7 ASB10 MTR RBM20 RXRG

4.91e-05188945ba7f7ce034c0f42742bf2461f68f8d343ee593a5
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN2 CYP26B1 RIN2 MACROD2 PDLIM4

4.91e-051889459b95730ddd13eb4624321bab3ab4989414977ca3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ASB10 LTBP1 ARHGEF17 RBM20 NOTCH3

5.03e-05189945127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN2 ADAM15 HIF3A ITGA5 OVCH1

5.03e-0518994512b6f1c3bf526b90e112374bf937701f645c5780
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ASB10 LTBP1 ARHGEF17 RBM20 NOTCH3

5.03e-051899452cfb4d12f75678d1619f4743838a0e954bd57761
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EREG FBLN2 FSTL3 LTBP1 ITGA5

5.03e-05189945562f8bf5a7d38afb4a8f2415d617d5f79cfb7e3f
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EREG FBLN2 FSTL3 LTBP1 ITGA5

5.03e-05189945270dd4a0fc5260288fe6829837942c78b40ecec4
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBLN2 CTTNBP2 ADAM15 LTBP1 ITGA5

5.16e-05190945aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCelldroplet-Kidney-nan-21m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB10 LTBP1 ARHGEF17 NOTCH3 PLEKHH3

5.16e-05190945e04f47705851563515b6a66a2634cf7a574f7bda
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPG RAD54B BARD1 ESPL1 RBM20

5.16e-05190945b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 LTBP1 ARHGEF17 RBM20 NOTCH3

5.16e-051909455681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBLN2 CTTNBP2 CYP26B1 ADAM15 LTBP1

5.29e-051919454b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

MACROD2 MTR HIF3A PUM1 IL17RB

5.42e-05192945916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ASB10 OSBPL5 LTBP1 RBM20 NOTCH3

5.42e-05192945bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

MYH7 KIF21A MACROD2 RBM20 PDZRN3

5.42e-05192945ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ASB10 OSBPL5 LTBP1 RBM20 NOTCH3

5.42e-05192945b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBLN2 ADAM15 RIN2 ITGA5 PDLIM4

5.42e-05192945717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN2 ADAM15 OSBPL5 LRP5 LTBP1

5.56e-05193945daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

KIF21A MACROD2 LRP5 DNAH14 IL17RB

5.56e-05193945503a979328c68b096680b71359a26f02fafdff35
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

MACROD2 MTR HIF3A PUM1 IL17RB

5.56e-05193945e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP26B1 FSTL3 LTBP1 HIF3A PDZRN3

5.56e-05193945261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCAF2 ISLR2 CYP26B1 ADAM15 OVCH1

5.56e-051939451f978e102a029a6beb10913052cd0a20c7253e8e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

EREG FPR2 ITGA5 NLRP3 ZNF697

5.56e-0519394500c9c2945d2bdaa128e054cf3c59df86a279b659
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ITGA11 LTBP1 ARHGEF17 PDZRN3 NOTCH3

5.69e-051949452d66091097e106c7bee22e5281f50724700bdf8d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EREG RIN2 FPR2 ITGA5 NLRP3

5.69e-05194945935ec4554d740935d9d9a59d9d6b5293d1c27d1f
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

MYH7 KIF21A MACROD2 RBM20 PDZRN3

5.83e-05195945f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

MYH7 KIF21A MACROD2 RBM20 PDZRN3

5.83e-0519594575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellILEUM-non-inflamed-(9)_Enteric_neurons|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FBLN2 FSTL3 RIN2 RXRG PDLIM4

5.98e-05196945998aa523555ed6bc9c1b5cacbf7ba77c7b218e6b
ToppCellILEUM-non-inflamed-(9)_Neuro_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FBLN2 FSTL3 RIN2 RXRG PDLIM4

5.98e-051969452b08cd6730119d5dea0152709ab8de580b66cd3c
ToppCellmetastatic_Lymph_Node-Fibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

ISLR2 ITGA11 FBLN2 LTBP1 PDZRN3

5.98e-05196945275e153347caf94edc0c50021bbab49c8696fecb
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLDIP3 LTBP1 PUM1 NOTCH3 PDLIM4

6.12e-051979455bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CYP26B1 FSTL3 LTBP1 CSMD3 PDZRN3

6.12e-051979452cb1f557ce1400398975de94638126b4522567f3
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP26B1 ADAM15 LTBP1 HIF3A ITGA5

6.12e-0519794556afed433887cb2766eb30f22aec195148db33ab
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP1 ITGA5 RBM20 PDZRN3 NOTCH3

6.27e-05198945bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCell(0)_NK_cells-(0)_NK_FCGR3Apos|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

GTF3C1 RIN2 OSBPL5 ITGA5 TTC38

6.27e-05198945eba39656c6f699ab297b652ded8cb9727b49593c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EREG RIN2 FPR2 ITGA5 NLRP3

6.42e-05199945d3f77acb36ac7c56a47ca98b695f46ae5b9ecd12
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA11 FBLN2 FSTL3 LTBP1 PDZRN3

6.42e-0519994521335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP1 ITGA5 RBM20 PDZRN3 NOTCH3

6.42e-05199945b1753474152b82a0b811b9878c890a359e14919a
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FBLN2 CYP26B1 LTBP1 HIF3A RXRG

6.58e-05200945ac6b8bc9998d303f788511b8f111e682ea9f3df8
ToppCellParenchyma_COVID-19-Endothelial-TX-Artery|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CYP26B1 ADAM15 LTBP1 HIF3A ITGA5

6.58e-0520094534b279804475ea58fbb052b96f44128c082627a9
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ITGA11 FBLN2 FSTL3 LTBP1 HIF3A

6.58e-052009452022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYP26B1 ADAM15 LTBP1 HIF3A ITGA5

6.58e-052009458552cc7a439449b30b59760c3e8667217b9852b5
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA11 LTBP1 RBM20 PDZRN3 NOTCH3

6.58e-05200945a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellParenchymal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FBLN2 FSTL3 LTBP1 PDZRN3 NOTCH3

6.58e-052009452e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Artery|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FBLN2 CTTNBP2 CYP26B1 ADAM15 LTBP1

6.58e-0520094577ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

FBLN2 CTTNBP2 CYP26B1 ADAM15 LTBP1

6.58e-0520094565b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FBLN2 CTTNBP2 CYP26B1 ADAM15 LTBP1

6.58e-05200945ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NCAPG RAD54B BARD1 ESPL1 IL17RB

6.58e-05200945203b9a5de4430713da01b3331e69381db449a3a0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NCAPG RAD54B BARD1 ESPL1 IL17RB

6.58e-05200945a854e19703dc920e48304541e2b06ed013292f3e
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

FBLN2 CTTNBP2 CYP26B1 ADAM15 LTBP1

6.58e-05200945b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

FBLN2 FSTL3 LTBP1 PDZRN3 NOTCH3

6.58e-05200945d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP26B1 ADAM15 LTBP1 HIF3A ITGA5

6.58e-0520094545c08f1befe78553bbadcc2fcffb6138306638f3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

VWA5B2 ITGA11 CYP26B1 CSMD3 USH2A

6.58e-05200945fe772d98c461c973dfc082e1fc50117c27ced804
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_only / Treatment groups by lineage, cell group, cell type

ISLR2 LTBP1 ARHGEF17 NOTCH3 PLEKHH3

6.58e-052009457c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCellThalamus-Macroglia-OLIGODENDROCYTE-O2-Trf|Thalamus / BrainAtlas - Mouse McCarroll V32

KIF13B TDRD6 IL17RB OTUD7B

1.34e-041239443b97ff4de1e16652291db1c9e2a8474675fcdbfe
ToppCellThalamus-Macroglia-OLIGODENDROCYTE-O2|Thalamus / BrainAtlas - Mouse McCarroll V32

KIF13B TDRD6 IL17RB OTUD7B

1.34e-04123944fd981879529ced0e3023a1f3f8794ce8ff4d99a8
ToppCellThalamus-Macroglia-OLIGODENDROCYTE|Thalamus / BrainAtlas - Mouse McCarroll V32

KIF13B TDRD6 IL17RB OTUD7B

1.61e-04129944b3cb0c10659d1216b8f7de3aa1f9aac101cb65dd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NLRP14 BARD1 IL17RB RHCE

1.66e-041309441720f16ac06951c3f57b6c3b0944670a571203d1
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|367C / Donor, Lineage, Cell class and subclass (all cells)

CYP26B1 FPR2 OVCH1 IL17RB

1.71e-04131944aeeb5718b3a7122492ad2659d5c8112f60839ff3
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NCAPG PIWIL2 NLRP3

1.92e-0453943d55030028f9ac970afb343ef6e1c41ab4bb2ae53
Diseaselower face morphology measurement

ITGA11 NLRP14 OSBPL5 LTBP1

3.38e-04109894EFO_0010948
Diseaseblood nickel measurement

FAT2 MACROD2 USH2A NLRP3

4.87e-04120894EFO_0007583
DiseaseDental enamel hypoplasia

MACROD2 MAP3K21

5.82e-0412892EFO_1001304
Diseaseage at last pregnancy measurement

MST1R MACROD2

8.00e-0414892EFO_0009440
Diseasemedial orbital frontal cortex volume measurement

FAT2 MACROD2

2.58e-0325892EFO_0010315
DiseaseSquamous cell carcinoma of esophagus

FAT2 CYP26B1 NOTCH3

3.01e-0395893C0279626

Protein segments in the cluster

PeptideGeneStartEntry
LCIGVSQGACAEHLP

nan

26

A8MUN3
ILREPVCLGGCEHIF

BARD1

56

Q99728
RCLAGHCGIPELIVN

CSMD3

2811

Q7Z407
GPGLVCIDHRCQRVD

ADAM15

636

Q13444
HLCRGPGTLECAELL

ASB10

186

Q8WXI3
LGALICIECSGIHRN

AGAP2

961

Q99490
VLPHTAVCLLCGEAG

FBXL19

81

Q6PCT2
LVLATVPLLGAACCH

ISLR2

601

Q6UXK2
CLQGLLENSPHLICI

RAD54B

571

Q9Y620
AGRVVHICNLPEGSC

RBM20

516

Q5T481
RCQEGCGLPLTHGEQ

PDZRN3

141

Q9UPQ7
HQLRCNGVLEGIRIC

MYH7

691

P12883
QDPGVLGCPRTCLHA

NUP205

1021

Q92621
LGCPRTCLHAILNIL

NUP205

1026

Q92621
LCIGAVPGLQPRCHR

ARHGEF17

1551

Q96PE2
VHCQEPRRQLAGGPC

OTUD7B

706

Q6GQQ9
CEHRGLAGLACAPIK

OR52E4

181

Q8NGH9
NCLLVGAIAIPHCVL

NOL9

636

Q5SY16
GAIAIPHCVLKCQRG

NOL9

641

Q5SY16
PHCVLKCQRGIEGTV

NOL9

646

Q5SY16
PVAKLCELVHLCGGR

MCPH1

771

Q8NEM0
CELVHLCGGRVSQVP

MCPH1

776

Q8NEM0
IGFIALDRCICVLHP

FPR2

116

P25090
LQEVGLHGNPIRCDC

LRRN2

361

O75325
ILHSGGCPCEGTLRL

CYP26B1

331

Q9NR63
LPCHRLQVGDVCISI

ATXN1L

566

P0C7T5
HATRCGCPIGLELLS

LRP5

621

O75197
CIRHKGTVVLCPQTG

IL17RB

261

Q9NRM6
CVLNGELPLRSRCHI

DDX56

286

Q9NY93
LQHLLRQCGIPFGAE

HMGXB3

1011

Q12766
LPGELCQHLCINTVG

FBLN2

611

P98095
SARLCQPEGIHICDG

PCK2

51

Q16822
RGCSEGHCLVTPEIQ

FAT2

4026

Q9NYQ8
PDICGAGHCINLPVR

LTBP1

881

Q14766
SIGANPCEHLGRCVN

NOTCH3

396

Q9UM47
IAHLPLLICCLQGLG

PI4KA

476

P42356
CQAHGEPVLGLCPLL

PDZD3

81

Q86UT5
VPLLFRALVHLGCVC

POLE

1431

Q07864
CPVIHGNCTKLNLGR

ITGA11

76

Q9UKX5
QLCGHITHRGPCVAV

MEAK7

281

Q6P9B6
LPLCGHRRVEGFLCE

OR2C1

166

O95371
EVGLRPHQVEVVCCL

NUDT7

96

P0C024
GCRVIQRILEHCLPD

PUM1

1006

Q14671
CFRLRCELGPLHQQE

ITGA5

916

P08648
ACAISEPLCQHLGLV

ESPL1

476

Q14674
KNCLEILCRHGGLEP

CTTNBP2

926

Q8WZ74
INLLGFLGLVHCLPC

FSTL3

81

O95633
ALLGRHCPLCVPAGE

LINC01387

86

J3KSC0
CGGQLFIIPCSRVGH

GALNTL5

346

Q7Z4T8
CRLGHCPDPVLVNGE

C4BPB

76

P20851
EPGVVGLCCAVLPIH

DNAH14

131

Q0VDD8
LCPQGHRLVGGRKCQ

LTBP3

851

Q9NS15
CAGRVPALLLCLGFH

EREG

11

O14944
DGNICRHLLPRVQCP

BPHL

221

Q86WA6
VHIQDVGGLICRACN

C9orf57

71

Q5W0N0
CLQCDPLVLEALGHL

IZUMO2

21

Q6UXV1
ELRCVCLQTTQGVHP

CXCL5

46

P42830
CVCGALKRARLVHPG

POLDIP3

301

Q9BY77
VGTVLLHCCELIERP

OSBPL5

166

Q9H0X9
VDGCIHRAAGPCLLA

MACROD2

101

A1Z1Q3
LCETLQHPGCNIRRL

NLRP3

761

Q96P20
IQLCGMGILPEHCII

KIF13B

481

Q9NQT8
CVLGSREQLCIHPEV

RTEL1

136

Q9NZ71
YLLVGLSRLQCGHCP

RTP5

46

Q14D33
KLGVTGLRCNQCEPH

USH2A

871

O75445
VCEVLSCDHNGGLPR

ROPN1B

141

Q9BZX4
RQELLCTVHCPGAGA

PLEKHH3

401

Q7Z736
LVNAILPGLCIHCSL

TDRD6

1406

O60522
LPGLCIHCSLQGFEV

TDRD6

1411

O60522
GRVVLAAHECLLCAP

TCAF2

266

A6NFQ2
LRGVCLQQPHLCLVL

MAP3K21

186

Q5TCX8
LRNFHLPCGQERGCL

PHF7

116

Q9BWX1
VRQGCGIPTHYVCVL

PIWIL2

896

Q8TC59
LSRRIAGGEEACPHC

OVCH1

571

Q7RTY7
LQCLVLICEAIPHPG

HIF3A

216

Q9Y2N7
LSGLQGLPECTRCGH

PDLIM4

246

P50479
ISVSHGEPLCIGLNC

MTR

246

Q99707
PLLCLCVVAAHLAGA

CILP2

6

Q8IUL8
IHPVVRNLAVLCLGC

NCAPG

596

Q9BPX3
CPASLRQLCLINGVH

RIN2

236

Q8WYP3
VILIGVCTHLGCVPI

UQCRFS1

211

P47985
CPLCQEQLVGRPALH

ZFHX2

1011

Q9C0A1
CLPVCCNRVLGIHHI

RHCE

311

P18577
VAGLSCVLCKQPRHG

SLC35B2

166

Q8TB61
LCTIRQAAECHPPVG

STAG2

526

Q8N3U4
GIRAFPLQCIHIAEG

KIF21A

1331

Q7Z4S6
CVAVHCVAGLGRAPV

PTP4A2

96

Q12974
PGSLVKHICAICGDR

RXRG

131

P48443
VLGLPIRCIHSEEGC

TRAF4

76

Q9BUZ4
RLHTGERPNLCADCG

ZNF697

281

Q5TEC3
GNEPRECAHCLLVQG

ULK2

636

Q8IYT8
NCQHLLARDVGLPLC

TTC38

366

Q5R3I4
APRCHVVIRGLCGEQ

VWA5B2

836

Q8N398
ILIGVCTHLGCVPIA

UQCRFS1P1

221

P0C7P4
LAVLLPGRHPCDCLG

TRIP4

161

Q15650
VSLRLQEIHPECGPC

GTF3C1

306

Q12789
LQVCVDGECHILGRV

MST1R

931

Q04912
PVNQRACHILECPEG

SHC1

281

P29353
AAEGLVPCGSLCIAH

TRIO

1706

O75962
LHCRASGVGVCQLPG

ZAN

1921

Q9Y493
DGVQLLCEALRHPKC

NLRP14

801

Q86W24