Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor-activated receptor activity	FAM72D FAM72C FAM72B FAM72A	9.79e-12	4	38	4	GO:0031551
GeneOntologyBiologicalProcess	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72B FAM72A	4.89e-11	5	38	4	GO:0031549
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72B FAM72A	3.41e-10	7	38	4	GO:0031548
GeneOntologyBiologicalProcess	brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72C FAM72B FAM72A	9.67e-09	14	38	4	GO:0031547
GeneOntologyBiologicalProcess	negative regulation of peptidyl-tyrosine phosphorylation	FAM72D LRRK1 FAM72C FAM72B FAM72A	7.52e-08	59	38	5	GO:0050732
GeneOntologyBiologicalProcess	negative regulation of protein tyrosine kinase activity	FAM72D FAM72C FAM72B FAM72A	2.59e-07	30	38	4	GO:0061099
GeneOntologyBiologicalProcess	negative regulation of signaling receptor activity	FAM72D FAM72C FAM72B FAM72A	3.86e-07	33	38	4	GO:2000272
GeneOntologyBiologicalProcess	regulation of protein tyrosine kinase activity	FAM72D FAM72C FAM72B FAM72A	7.77e-06	69	38	4	GO:0061097
GeneOntologyBiologicalProcess	positive regulation of apoptotic process	FAM72D ATM FAM72C RFPL1 MUC2 FAM72B NOTCH2 FAM72A	4.02e-05	718	38	8	GO:0043065
GeneOntologyBiologicalProcess	positive regulation of programmed cell death	FAM72D ATM FAM72C RFPL1 MUC2 FAM72B NOTCH2 FAM72A	4.92e-05	739	38	8	GO:0043068
GeneOntologyBiologicalProcess	negative regulation of protein kinase activity	FAM72D SPRY2 FAM72C FAM72B FAM72A	5.08e-05	221	38	5	GO:0006469
GeneOntologyBiologicalProcess	peptidyl-amino acid modification	FAM72D SPRY2 NKTR ATM LRRK1 FAM72C FAM72B FAM72A TTLL7	5.40e-05	976	38	9	GO:0018193
GeneOntologyBiologicalProcess	negative regulation of protein phosphorylation	FAM72D SPRY2 LRRK1 FAM72C FAM72B FAM72A	5.86e-05	375	38	6	GO:0001933
GeneOntologyBiologicalProcess	negative regulation of kinase activity	FAM72D SPRY2 FAM72C FAM72B FAM72A	6.93e-05	236	38	5	GO:0033673
GeneOntologyBiologicalProcess	negative regulation of phosphorylation	FAM72D SPRY2 LRRK1 FAM72C FAM72B FAM72A	8.48e-05	401	38	6	GO:0042326
GeneOntologyBiologicalProcess	regulation of signaling receptor activity	FAM72D FAM72C FAM72B FAM72A	9.70e-05	131	38	4	GO:0010469
GeneOntologyBiologicalProcess	regulation of peptidyl-tyrosine phosphorylation	FAM72D LRRK1 FAM72C FAM72B FAM72A	1.35e-04	272	38	5	GO:0050730
GeneOntologyBiologicalProcess	negative regulation of transferase activity	FAM72D SPRY2 FAM72C FAM72B FAM72A	1.37e-04	273	38	5	GO:0051348
GeneOntologyBiologicalProcess	female mating behavior	THRA PGR	2.16e-04	12	38	2	GO:0060180
GeneOntologyBiologicalProcess	negative regulation of phosphate metabolic process	FAM72D SPRY2 LRRK1 FAM72C FAM72B FAM72A	2.21e-04	478	38	6	GO:0045936
GeneOntologyBiologicalProcess	negative regulation of phosphorus metabolic process	FAM72D SPRY2 LRRK1 FAM72C FAM72B FAM72A	2.26e-04	480	38	6	GO:0010563
GeneOntologyBiologicalProcess	peptidyl-tyrosine phosphorylation	FAM72D LRRK1 FAM72C FAM72B FAM72A	3.17e-04	327	38	5	GO:0018108
GeneOntologyBiologicalProcess	negative regulation of protein modification process	FAM72D SPRY2 LRRK1 FAM72C FAM72B FAM72A	3.19e-04	512	38	6	GO:0031400
GeneOntologyBiologicalProcess	peptidyl-tyrosine modification	FAM72D LRRK1 FAM72C FAM72B FAM72A	3.26e-04	329	38	5	GO:0018212
GeneOntologyBiologicalProcess	cell surface receptor protein tyrosine kinase signaling pathway	FAM72D SPRY2 CRIM1 FAM72C SLC30A10 FAM72B FAM72A	3.76e-04	747	38	7	GO:0007169
GeneOntologyBiologicalProcess	regulation of transferase activity	FAM72D SPRY2 ATM FAM72C FAM72B NOTCH2 FAM72A	6.11e-04	810	38	7	GO:0051338
GeneOntologyBiologicalProcess	female gamete generation	ZAR1 SPIRE1 ATM PGR	7.36e-04	223	38	4	GO:0007292
GeneOntologyBiologicalProcess	osteoclast development	LRRK1 NOTCH2	7.46e-04	22	38	2	GO:0036035
GeneOntologyBiologicalProcess	bone cell development	LRRK1 NOTCH2	7.46e-04	22	38	2	GO:0098751
GeneOntologyBiologicalProcess	stress response to metal ion	MUC2 SLC30A10	7.46e-04	22	38	2	GO:0097501
GeneOntologyBiologicalProcess	regulation of protein kinase activity	FAM72D SPRY2 FAM72C FAM72B NOTCH2 FAM72A	8.12e-04	611	38	6	GO:0045859
GeneOntologyBiologicalProcess	detoxification of inorganic compound	MUC2 SLC30A10	9.65e-04	25	38	2	GO:0061687
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	FAM72D SPRY2 CRIM1 FAM72C SLC30A10 FAM72B NOTCH2 FAM72A	1.22e-03	1186	38	8	GO:0007167
MousePheno	abnormal somatic hypermutation frequency	FAM72D FAM72C FAM72B FAM72A	9.73e-08	19	33	4	MP:0004815
MousePheno	increased B cell apoptosis	FAM72D FAM72C FAM72B FAM72A	5.06e-07	28	33	4	MP:0008782
MousePheno	increased germinal center B cell number	FAM72D FAM72C FAM72B FAM72A	7.74e-07	31	33	4	MP:0008177
MousePheno	abnormal class switch recombination	FAM72D ATM FAM72C FAM72B FAM72A	1.20e-06	81	33	5	MP:0004816
MousePheno	abnormal B cell apoptosis	FAM72D FAM72C FAM72B FAM72A	4.27e-06	47	33	4	MP:0008781
MousePheno	abnormal germinal center B cell number	FAM72D FAM72C FAM72B FAM72A	8.06e-06	55	33	4	MP:0013680
MousePheno	abnormal germinal center B cell morphology	FAM72D FAM72C FAM72B FAM72A	8.06e-06	55	33	4	MP:0008176
MousePheno	abnormal mature B cell morphology	FAM72D ATM FAM72C FAM72B NOTCH2 FAM72A	1.98e-05	244	33	6	MP:0008171
MousePheno	abnormal professional antigen presenting cell morphology	FAM72D ATM LRRK1 THRA FAM72C FAM72B NOTCH2 FAM72A PGR	3.27e-05	726	33	9	MP:0008195
MousePheno	increased mature B cell number	FAM72D ATM FAM72C FAM72B FAM72A	4.27e-05	168	33	5	MP:0008210
MousePheno	increased blood urea nitrogen level	FAM72D SLC26A3 THRA FAM72C FAM72B FAM72A	5.13e-05	289	33	6	MP:0005565
MousePheno	kidney cyst	FAM72D CRIM1 FAM72C FAM72B FAM72A	5.48e-05	177	33	5	MP:0003675
MousePheno	polycystic kidney	FAM72D FAM72C FAM72B FAM72A	6.21e-05	92	33	4	MP:0008528
MousePheno	abnormal mature B cell number	FAM72D ATM FAM72C FAM72B NOTCH2 FAM72A	7.85e-05	312	33	6	MP:0013701
MousePheno	abnormal trabecular bone thickness	LRRK1 THRA NOTCH2 PGR	7.95e-05	98	33	4	MP:0009345
MousePheno	increased compact bone thickness	LRRK1 THRA PGR	1.20e-04	41	33	3	MP:0004148
MousePheno	increased trabecular bone thickness	LRRK1 THRA PGR	1.39e-04	43	33	3	MP:0009347
MousePheno	abnormal compact bone thickness	LRRK1 THRA NOTCH2 PGR	1.86e-04	122	33	4	MP:0000134
MousePheno	abnormal blood urea nitrogen level	FAM72D SLC26A3 THRA FAM72C FAM72B FAM72A	2.62e-04	389	33	6	MP:0005265
MousePheno	increased B cell number	FAM72D ATM FAM72C FAM72B FAM72A	4.01e-04	271	33	5	MP:0005014
MousePheno	osteosclerosis	LRRK1 THRA	4.83e-04	14	33	2	MP:0005422
MousePheno	uremia	FAM72D SLC26A3 THRA FAM72C FAM72B FAM72A	4.87e-04	437	33	6	MP:0009644
MousePheno	abnormal B cell differentiation	FAM72D ATM FAM72C FAM72B FAM72A	5.22e-04	287	33	5	MP:0002144
MousePheno	abnormal trabecular bone morphology	SPRY2 LRRK1 THRA NOTCH2 PGR	5.39e-04	289	33	5	MP:0000130
MousePheno	abnormal cyst	FAM72D CRIM1 FAM72C FAM72B FAM72A	5.82e-04	294	33	5	MP:0031310
MousePheno	abnormal compact bone morphology	LRRK1 THRA NOTCH2 PGR	6.85e-04	172	33	4	MP:0003797
MousePheno	abnormal bone resorption	LRRK1 THRA NOTCH2	6.93e-04	74	33	3	MP:0004945
MousePheno	increased circulating thyroid-stimulating hormone level	THRA SLC30A10	7.19e-04	17	33	2	MP:0005122
MousePheno	abnormal compact bone volume	THRA NOTCH2	8.08e-04	18	33	2	MP:0010963
MousePheno	abnormal osteoclast morphology	LRRK1 THRA NOTCH2 PGR	8.64e-04	183	33	4	MP:0004982
MousePheno	increased bone mass	LRRK1 THRA PGR	8.70e-04	80	33	3	MP:0005605
MousePheno	small vertebral body	SPRY2 NOTCH2	9.01e-04	19	33	2	MP:0004670
MousePheno	decreased compact bone area	THRA NOTCH2	1.00e-03	20	33	2	MP:0010968
MousePheno	increased thyroid-stimulating hormone level	THRA SLC30A10	1.00e-03	20	33	2	MP:0005135
MousePheno	abnormal glomerular capillary endothelium morphology	CRIM1 NOTCH2	1.10e-03	21	33	2	MP:0011453
MousePheno	decreased activity of thyroid gland	THRA SLC30A10	1.10e-03	21	33	2	MP:0003503
Domain	FAM72	FAM72D FAM72C FAM72B FAM72A	1.46e-11	4	38	4	PF14976
Domain	FAM72	FAM72D FAM72C FAM72B FAM72A	1.46e-11	4	38	4	IPR026768
Domain	ZnF_NFX	NFXL1 ZNFX1	1.21e-05	3	38	2	SM00438
Domain	zf-NF-X1	NFXL1 ZNFX1	1.21e-05	3	38	2	PF01422
Domain	Znf_NFX1	NFXL1 ZNFX1	1.21e-05	3	38	2	IPR000967
Domain	LRR_5	LRRC8B LRFN5	1.80e-04	10	38	2	PF13306
Domain	LRR_5	LRRC8B LRFN5	1.80e-04	10	38	2	IPR026906
Domain	-	RNF144B SPIRE1 RNF40 RFPL1 ZFYVE1 ZFYVE21	2.68e-04	449	38	6	3.30.40.10
Domain	Growth_fac_rcpt_	CCN6 STAB2 CRIM1 NOTCH2	2.77e-04	156	38	4	IPR009030
Domain	Znf_RING/FYVE/PHD	RNF144B SPIRE1 RNF40 RFPL1 ZFYVE1 ZFYVE21	3.02e-04	459	38	6	IPR013083
Domain	Leu-rich_rpt_typical-subtyp	LRRC8B LRRK1 LRFN5 LRIT1	4.47e-04	177	38	4	IPR003591
Domain	LRR_TYP	LRRC8B LRRK1 LRFN5 LRIT1	4.47e-04	177	38	4	SM00369
Domain	CTCK_1	CCN6 MUC2	6.04e-04	18	38	2	PS01185
Domain	IB	CCN6 CRIM1	6.04e-04	18	38	2	SM00121
Domain	VWC_out	CRIM1 MUC2	6.74e-04	19	38	2	SM00215
Domain	LRR	LRRC8B LRRK1 LRFN5 LRIT1	7.22e-04	201	38	4	PS51450
Domain	IGFBP_N_2	CCN6 CRIM1	7.48e-04	20	38	2	PS51323
Domain	IGFBP-like	CCN6 CRIM1	7.48e-04	20	38	2	IPR000867
Domain	IGFBP	CCN6 CRIM1	7.48e-04	20	38	2	PF00219
Domain	CT	CCN6 MUC2	9.08e-04	22	38	2	SM00041
Domain	LRR_1	LRRC8B LRRK1 LRFN5 LRIT1	9.93e-04	219	38	4	PF00560
Domain	Cys_knot_C	CCN6 MUC2	1.17e-03	25	38	2	IPR006207
Domain	CTCK_2	CCN6 MUC2	1.17e-03	25	38	2	PS01225
Domain	FYVE	ZFYVE1 ZFYVE21	1.58e-03	29	38	2	PF01363
Domain	FYVE	ZFYVE1 ZFYVE21	1.58e-03	29	38	2	SM00064
Domain	Znf_FYVE-rel	ZFYVE1 ZFYVE21	2.17e-03	34	38	2	IPR017455
Domain	Leu-rich_rpt	LRRC8B LRRK1 LRFN5 LRIT1	2.17e-03	271	38	4	IPR001611
Domain	VWFC_1	CRIM1 MUC2	2.43e-03	36	38	2	PS01208
Domain	VWC	CRIM1 MUC2	2.71e-03	38	38	2	SM00214
Domain	Znf_FYVE	ZFYVE1 ZFYVE21	2.71e-03	38	38	2	IPR000306
Domain	VWFC_2	CRIM1 MUC2	2.71e-03	38	38	2	PS50184
Domain	ZF_RING_1	RNF144B NFXL1 RNF40 RFPL1	2.81e-03	291	38	4	PS00518
Domain	ZF_FYVE	ZFYVE1 ZFYVE21	2.99e-03	40	38	2	PS50178
Domain	ZF_RING_2	RNF144B NFXL1 RNF40 RFPL1	3.06e-03	298	38	4	PS50089
Domain	Znf_FYVE_PHD	SPIRE1 ZFYVE1 ZFYVE21	3.29e-03	147	38	3	IPR011011
Domain	VWF_dom	CRIM1 MUC2	3.30e-03	42	38	2	IPR001007
Domain	zf-C4	THRA PGR	3.94e-03	46	38	2	PF00105
Domain	NUCLEAR_REC_DBD_1	THRA PGR	3.94e-03	46	38	2	PS00031
Domain	Znf_hrmn_rcpt	THRA PGR	3.94e-03	46	38	2	IPR001628
Domain	Nuclear_hrmn_rcpt	THRA PGR	3.94e-03	46	38	2	IPR001723
Domain	ZnF_C4	THRA PGR	3.94e-03	46	38	2	SM00399
Domain	NUCLEAR_REC_DBD_2	THRA PGR	3.94e-03	46	38	2	PS51030
Domain	-	LRRC8B LRRK1 LRFN5 LRIT1	3.99e-03	321	38	4	3.80.10.10
Domain	-	THRA PGR	4.11e-03	47	38	2	1.10.565.10
Domain	Znf_RING	RNF144B NFXL1 RNF40 RFPL1	4.21e-03	326	38	4	IPR001841
Domain	HOLI	THRA PGR	4.29e-03	48	38	2	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	THRA PGR	4.29e-03	48	38	2	IPR000536
Domain	Hormone_recep	THRA PGR	4.29e-03	48	38	2	PF00104
Domain	L_dom-like	LRRC8B LRRK1 LRFN5 LRIT1	4.31e-03	328	38	4	IPR032675
Domain	-	THRA PGR	6.00e-03	57	38	2	3.30.50.10
Domain	Znf_NHR/GATA	THRA PGR	6.20e-03	58	38	2	IPR013088
Domain	FN3	COL6A3 LRFN5 LRIT1	7.64e-03	199	38	3	PS50853
Pubmed	Fam72a enforces error-prone DNA repair during antibody diversification.	FAM72D FAM72C FAM72B FAM72A	1.21e-12	4	38	4	34819671
Pubmed	Identification and characterisation of the novel amyloid-beta peptide-induced protein p17.	FAM72D FAM72C FAM72B FAM72A	6.05e-12	5	38	4	19755123
Pubmed	All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci.	FAM72D FAM72C FAM72B FAM72A	6.05e-12	5	38	4	26206078
Pubmed	FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.	FAM72D FAM72C FAM72B FAM72A	1.81e-11	6	38	4	34819670
Pubmed	cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.	FAM72D FAM72C FAM72B FAM72A	1.64e-09	15	38	4	1741163
Pubmed	RNF144B stimulates the proliferation and inhibits the apoptosis of human spermatogonial stem cells via the FCER2/NOTCH2/HES1 pathway and its abnormality is associated with azoospermia.	RNF144B NOTCH2	3.48e-06	3	38	2	35699595
Pubmed	Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.	RNF40 ATM	6.96e-06	4	38	2	21362549
Pubmed	Uterine Notch2 facilitates pregnancy recognition and corpus luteum maintenance via upregulating decidual Prl8a2.	NOTCH2 PGR	1.16e-05	5	38	2	34460816
Pubmed	Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoter.	THRA PGR	4.16e-05	9	38	2	10480874
Pubmed	T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha.	THRA PGR	4.16e-05	9	38	2	12874288
Pubmed	The pro-apoptotic protein death-associated protein 3 (DAP3) interacts with the glucocorticoid receptor and affects the receptor function.	THRA PGR	6.35e-05	11	38	2	10903152
Pubmed	Differential interaction of nuclear receptors with the putative human transcriptional coactivator hTIF1.	THRA PGR	9.00e-05	13	38	2	9115274
Pubmed	Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.	SPRY2 NOTCH2	9.00e-05	13	38	2	18708576
Pubmed	Deletion of maternal UHRF1 severely reduces mouse oocyte quality and causes developmental defects in preimplantation embryos.	ZAR1 ATM	1.05e-04	14	38	2	30995416
Pubmed	Hemidesmosome integrity protects the colon against colitis and colorectal cancer.	SLC26A3 MUC2	1.76e-04	18	38	2	27371534
Pubmed	Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium.	ATM MUC2	2.18e-04	20	38	2	26023099
Pubmed	A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior.	CRIM1 PGR	2.90e-04	23	38	2	35065713
Pubmed	Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.	NOTCH2 PGR	2.90e-04	23	38	2	36239412
Pubmed	Spatiotemporal cellular movement and fate decisions during first pharyngeal arch morphogenesis.	SPRY2 NOTCH2	3.72e-04	26	38	2	33328221
Pubmed	EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades.	NOTCH2 PGR	4.63e-04	29	38	2	24909139
Pubmed	The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.	ATM PGR	4.63e-04	29	38	2	19094228
Pubmed	Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms.	NOTCH2 PGR	4.63e-04	29	38	2	24971735
Pubmed	Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.	SPRY2 CRIM1	4.63e-04	29	38	2	20615956
Pubmed	Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning.	SPRY2 NOTCH2	4.96e-04	30	38	2	26450968
Pubmed	Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon.	SELENOP MUC2	6.01e-04	33	38	2	16618389
Pubmed	Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.	LRFN5 LRIT1	6.38e-04	34	38	2	18848646
Pubmed	NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.	ZAR1 RFPL1	7.56e-04	37	38	2	15326356
Pubmed	A complex oscillating network of signaling genes underlies the mouse segmentation clock.	SPRY2 RBM22	7.56e-04	37	38	2	17095659
Pubmed	Novel Cul3 binding proteins function to remodel E3 ligase complexes.	LRRC8B LRRK1	8.83e-04	40	38	2	25011449
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	MUC2 NOTCH2	9.28e-04	41	38	2	22675208
Cytoband	11q22-q23	ATM PGR	9.99e-06	6	38	2	11q22-q23
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE1 ZFYVE21	1.05e-03	31	28	2	81
GeneFamily	Nuclear hormone receptors	THRA PGR	2.60e-03	49	28	2	71
GeneFamily	Ring finger proteins	RNF144B RNF40 RFPL1	8.61e-03	275	28	3	58
GeneFamily	Solute carriers	SLC24A5 SLC26A3 SLC30A10	2.26e-02	395	28	3	752
GeneFamily	Fibronectin type III domain containing	LRFN5 LRIT1	2.53e-02	160	28	2	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	LRFN5 LRIT1	2.56e-02	161	28	2	593
Coexpression	GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN	ZAR1 SPRY2 LRRK1 CRIM1 NOTCH2	4.07e-06	166	38	5	M6701
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6\|TCGA-Kidney / Sample_Type by Project: Shred V9	FAM72D FAM72C FAM72B FAM72A	9.36e-06	156	38	4	d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B NFXL1 SPIRE1 NOTCH2	1.41e-05	173	38	4	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B NFXL1 SPIRE1 NOTCH2	1.41e-05	173	38	4	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B NFXL1 SPIRE1 NOTCH2	1.41e-05	173	38	4	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B NFXL1 SPIRE1 NOTCH2	1.47e-05	175	38	4	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC24A5 RNF144B SPRY2 SELENOP	1.75e-05	183	38	4	1e51aeaa8fc9383b424cce128a890e07cb6025f3
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	FAM72D FAM72C FAM72B FAM72A	1.75e-05	183	38	4	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-C\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM72D RFPL1 FAM72B FAM72A	1.95e-05	188	38	4	fe8c3283f1da7f3ae8dabaa338efebf3947d8658
ToppCell	wk_20-22-Hematologic-Myeloid-Cycling_DC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ATP8B3 FAM72D FAM72C FAM72A	2.08e-05	191	38	4	1da569ebcfab4e1a95315430ae77a17a1f119263
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B3 FAM72D FAM72C FAM72B	2.21e-05	194	38	4	06b8dc2e46f833707d5b68b324b4ff6c4d0dccf9
ToppCell	(1)_T_cell-(18)_cycling_gd_T\|(1)_T_cell / shred on Cell_type and subtype	FAM72D SPRY2 FAM72C FAM72B	2.44e-05	199	38	4	9369d0e4efe809e3e8757294ebebba5a47b30528
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPRY2 COL6A3 LRFN5 PGR	2.48e-05	200	38	4	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPRY2 COL6A3 SELENOP LRFN5	2.48e-05	200	38	4	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A3 LRRC8B CRIM1 NOTCH2	2.48e-05	200	38	4	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPRY2 COL6A3 SELENOP LRFN5	2.48e-05	200	38	4	440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPRY2 COL6A3 SELENOP LRFN5	2.48e-05	200	38	4	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCell	(18)_cycling_gd_T\|World / shred on Cell_type and subtype	FAM72D SPRY2 FAM72C FAM72B	2.63e-05	203	38	4	7d58929058c4769226a29febee1fd8ba64bc9f1a
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZAR1 CCN6 ATP8B3	3.46e-05	74	38	3	0d705c42e7741b861ba5a9f1af83b2c5c6f23fb6
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZAR1 CCN6 ATP8B3	3.46e-05	74	38	3	c49bda52aa4ead9483c2f27d63458034e75699bd
ToppCell	TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-7\|TCGA-Brain / Sample_Type by Project: Shred V9	FAM72D FAM72C FAM72B	1.64e-04	125	38	3	f655cb5725195e36c0e9ec97061d974466f11faa
ToppCell	pdx-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SPRY2 ZNFX1 CRIM1	2.50e-04	144	38	3	0b94d978262a826c9254145aa98c6c30240243f9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAM72D COL6A3 PGR	3.16e-04	156	38	3	363f1b661048d25895e2b8681c82894c957b29c0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAM72D COL6A3 PGR	3.16e-04	156	38	3	d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN6 SELENOP SLC30A10	3.16e-04	156	38	3	ea9223bb6450b22df11efa1705ab72dab005244a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN6 SELENOP SLC30A10	3.16e-04	156	38	3	586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 PGR	3.34e-04	159	38	3	2607b562903228274fbd96168ba826782fab0b53
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 PGR	3.34e-04	159	38	3	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFXL1 ATP8B3 MUC2	3.34e-04	159	38	3	6ec5489d55667e53bd9c021ada7de458bfef43a3
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	FAM72D FAM72C FAM72B	3.65e-04	164	38	3	ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPRY2 COL6A3 LRRK1	3.65e-04	164	38	3	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	C_02\|World / shred on cell type and cluster	SELENOP SLC26A3 SLC30A10	3.72e-04	165	38	3	a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP SLC26A3 SLC30A10	3.72e-04	165	38	3	ce79d217df88035457cd58f679e72dd98722ae22
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP8B3 FAM72C FAM72B	3.72e-04	165	38	3	eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell	droplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPIRE1 SELENOP STAB2	3.72e-04	165	38	3	6dda1c7fd812792bd2e4fb1a7ccb82a3552b0a3b
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SLC24A5 COL6A3 SELENOP	3.78e-04	166	38	3	65dafed953b01a9830b54309af75c7a561e88336
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC26A3 CATSPERD SLC30A10	3.85e-04	167	38	3	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	FAM72D FAM72C FAM72B	3.85e-04	167	38	3	315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCell	367C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SPRY2 FAM72A TTLL7	3.92e-04	168	38	3	80233a13135fd159f5764336a1fe67fba237776b
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FAM72D FAM72C FAM72B	4.13e-04	171	38	3	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B SPRY2 SELENOP	4.13e-04	171	38	3	a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP SLC26A3 SLC30A10	4.13e-04	171	38	3	5d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Enterocyte\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP SLC26A3 SLC30A10	4.13e-04	171	38	3	b0d616699e2110ffd6cf1868ed1f1a29f824e1fc
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP SLC26A3 SLC30A10	4.13e-04	171	38	3	e7dbee63cc39230aa12e7868ec78a129160c0d22
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B SPRY2 SLC30A10	4.20e-04	172	38	3	b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B SPRY2 SLC30A10	4.20e-04	172	38	3	2f1673fcb2356684d60871debb0f159aec553a1c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 CRIM1 PGR	4.41e-04	175	38	3	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 NOTCH2	4.41e-04	175	38	3	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 NOTCH2	4.41e-04	175	38	3	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC24A5 COL6A3 PGR	4.41e-04	175	38	3	12f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP SLC26A3 SLC30A10	4.49e-04	176	38	3	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 SELENOP CRIM1	4.56e-04	177	38	3	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 SELENOP CRIM1	4.56e-04	177	38	3	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	FAM72D FAM72C FAM72B	4.56e-04	177	38	3	ba701d3c90722d8bff70d0fa651899305cdad257
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B SPRY2 CRIM1	4.64e-04	178	38	3	5cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell	facs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B SPRY2 CRIM1	4.64e-04	178	38	3	f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY2 CRIM1 TTLL7	4.72e-04	179	38	3	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	frontal_cortex-Non-neuronal\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SELENOP LRRK1 NOTCH2	4.72e-04	179	38	3	ef01478bd03eb00f0ff2b6a8ae9244687c5f85aa
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SELENOP PGR	4.79e-04	180	38	3	ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell	390C-Fibroblasts-Fibroblast-G\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 SELENOP FAM72B	4.79e-04	180	38	3	137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	SELENOP FAM72C FAM72B	4.79e-04	180	38	3	4eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell	390C-Fibroblasts-Fibroblast-G-\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 SELENOP FAM72B	4.79e-04	180	38	3	cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC24A5 COL6A3 PGR	4.87e-04	181	38	3	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC24A5 COL6A3 PGR	4.87e-04	181	38	3	526e858a848470b6d2d5248788004d9735ed3add
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP8B3 FAM72C FAM72B	4.87e-04	181	38	3	e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FAM72D FAM72C FAM72B	5.03e-04	183	38	3	f03d87b556a3d50360d4eb6126b3466fe7266677
ToppCell	facs-Lung-Endomucin-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC24A5 RNF144B SELENOP	5.03e-04	183	38	3	3dc6cbe803e5b8c4201faaf2e6445898d71684e6
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC24A5 RNF144B SELENOP	5.11e-04	184	38	3	af5eb3650fafc808828eb42f68c0f1e9c278adbb
ToppCell	facs-Lung-Endomucin-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC24A5 RNF144B SELENOP	5.19e-04	185	38	3	f262b441ea3fe7f69dff33d5f171000371f3a3e5
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM72D FAM72B FAM72A	5.27e-04	186	38	3	86d145f965c311189e7996390eef491642417c5c
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SELENOP NKTR ATM	5.36e-04	187	38	3	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	COL6A3 CRIM1 TTLL7	5.36e-04	187	38	3	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 CRIM1 TTLL7	5.44e-04	188	38	3	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	CCN6 COL6A3 SELENOP	5.44e-04	188	38	3	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative\|Multiple_Sclerosis / Disease, Lineage and Cell Type	FAM72D FAM72C FAM72B	5.44e-04	188	38	3	6c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 SELENOP PGR	5.52e-04	189	38	3	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 PGR	5.52e-04	189	38	3	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	ILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NKTR ATM TTLL7	5.52e-04	189	38	3	a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 PGR	5.52e-04	189	38	3	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 CRIM1 TTLL7	5.61e-04	190	38	3	25525fee1da8a808034d9c916159fd0b6b26bce8
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 CRIM1 TTLL7	5.61e-04	190	38	3	a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCell	(2)_5-FU-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	SELENOP STAB2 CRIM1	5.61e-04	190	38	3	6b391b8a3ffcbdec3acaf242bc52fc3fc9da77c8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 PGR	5.69e-04	191	38	3	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM72D FAM72B FAM72A	5.69e-04	191	38	3	14144e0b0c12757358c9aa5dfc9b7edb2edde5c7
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	RNF144B SPIRE1 LRRK1	5.69e-04	191	38	3	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 PGR	5.69e-04	191	38	3	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	facs-Aorta-Heart-18m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY2 COL6A3 NOTCH2	5.78e-04	192	38	3	6d4fe7ea278efa4b9d43f8a3c282bc0e0e9abaea
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAM72D FAM72C FAM72B	5.78e-04	192	38	3	0a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY2 COL6A3 NOTCH2	5.78e-04	192	38	3	47aed7c8e6f5ce1084821212a04f568319e65fd6
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-oRG-26\|World / Primary Cells by Cluster	SPRY2 SELENOP NOTCH2	5.78e-04	192	38	3	b8cf9c3c6b954e93f7504d214e39662bfa8f96f5
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY2 COL6A3 NOTCH2	5.78e-04	192	38	3	2c6406bc97c3224099b94a43f2890f057b528fa6
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	COL6A3 NKTR ATM	5.78e-04	192	38	3	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM72D FAM72B FAM72A	5.78e-04	192	38	3	90d25b0b38f1cd7a98c76c1f9e38166da6d7a316
ToppCell	facs-Heart-RV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY2 COL6A3 NOTCH2	5.87e-04	193	38	3	76f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 LRFN5 PGR	5.96e-04	194	38	3	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 SELENOP LRFN5	5.96e-04	194	38	3	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-oRG\|World / Primary Cells by Cluster	SPRY2 SELENOP NOTCH2	5.96e-04	194	38	3	3a4bf6a7fac0e5bdbb4bb17041806d06a75974d9
ToppCell	facs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY2 COL6A3 NOTCH2	5.96e-04	194	38	3	48063c9fe3e12aeff0707acada1baa2f8621f093
ToppCell	(4)_Endothelial_cells-(42)_EC-sinusoidal\|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	COL6A3 SELENOP STAB2	5.96e-04	194	38	3	4199900d16623eca02d674d5ada7f0989e47955e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZAR1 COL6A3 LRFN5	5.96e-04	194	38	3	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-immature_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SELENOP STAB2 RFPL1	5.96e-04	194	38	3	bf8e78d53802ac758be1c3db833779c26a94e1d5
Disease	Dystonia	COL6A3 ATM SLC30A10	1.12e-04	86	32	3	C0013421
Disease	Benign neoplasm of bladder	ATM NOTCH2	1.19e-04	15	32	2	C0154017
Disease	Neoplasm of uncertain or unknown behavior of bladder	ATM NOTCH2	1.19e-04	15	32	2	C0496930
Disease	Carcinoma in situ of bladder	ATM NOTCH2	1.19e-04	15	32	2	C0154091
Disease	Dystonia, Limb	COL6A3 SLC30A10	1.53e-04	17	32	2	C0751093
Disease	pre-malignant neoplasm (biomarker_via_orthology)	ATM MUC2	1.53e-04	17	32	2	DOID:0060071 (biomarker_via_orthology)
Disease	Dystonia, Diurnal	COL6A3 SLC30A10	1.53e-04	17	32	2	C0393610
Disease	Dystonia, Paroxysmal	COL6A3 SLC30A10	1.72e-04	18	32	2	C0393588
Disease	Carcinoma of bladder	ATM NOTCH2	1.72e-04	18	32	2	C0699885
Disease	central corneal thickness	COL6A3 LRRK1 CRIM1 SLC30A10	3.37e-04	309	32	4	EFO_0005213
Disease	Adenoma	SELENOP MUC2	7.01e-04	36	32	2	C0001430
Disease	Adenoma, Microcystic	SELENOP MUC2	7.01e-04	36	32	2	C0205648
Disease	Adenoma, Monomorphic	SELENOP MUC2	7.01e-04	36	32	2	C0205649
Disease	Adenoma, Basal Cell	SELENOP MUC2	7.01e-04	36	32	2	C0205646
Disease	Follicular adenoma	SELENOP MUC2	7.01e-04	36	32	2	C0205647
Disease	Papillary adenoma	SELENOP MUC2	7.01e-04	36	32	2	C0205650
Disease	Adenoma, Trabecular	SELENOP MUC2	7.01e-04	36	32	2	C0205651
Disease	Endometrioma	SELENOP THRA PGR	7.04e-04	161	32	3	C0269102
Disease	Endometriosis	SELENOP THRA PGR	7.04e-04	161	32	3	C0014175
Disease	Lymphoma	ATM NOTCH2	8.66e-04	40	32	2	C0024299
Disease	severe acute respiratory syndrome, COVID-19	ATP8B3 COL6A3 CATSPERD ZFYVE1	1.34e-03	447	32	4	EFO_0000694, MONDO_0100096
Disease	Endometrial Neoplasms	RNF144B PGR	1.81e-03	58	32	2	C0014170

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTCPCCNTRKKDAVL	RNF40	946	O75150
KKCATQLCRRCKTVC	CATSPERD	756	Q86XM0
CQAVICCRVTPKQKA	ATP8B3	906	O60423
CQTCSKLKNVCQTCL	RBM22	71	Q9NW64
KAQICPKRCVCQILS	LRFN5	16	Q96NI6
LLLASPCIICCVCKS	RNF144B	276	Q7Z419
PCIICCVCKSCRGKK	RNF144B	281	Q7Z419
LCSRSPCKNKGTCVQ	NOTCH2	1066	Q04721
CPPCVQMLRIKCHCK	NFXL1	726	Q6ZNB6
LLSCCKNQCPKELPC	NFXL1	761	Q6ZNB6
RCVSILCCKFCKQVL	FAM72D	11	Q6L9T8
PLKCCKASRNALECL	LRRK1	426	Q38SD2
CCKKCEQTHCIIKRP	MUC2	4986	Q02817
RCVSILCCKFCKQVL	FAM72A	11	Q5TYM5
LCQKSLKCCRTIQPC	DEFB106A	46	Q8N104
QLTQSRVLCCLPCKV	LRRC8B	46	Q6P9F7
LVCCSALQKRCRKCF	LRIT1	546	Q9P2V4
RKNCPACRLRKCCQA	PGR	616	P06401
CGICLDKRCCIPNKS	CCN6	296	O95389
QLCTRCLSNCTKKSP	ATM	781	Q13315
RCVSILCCKFCKQVL	FAM72C	11	H0Y354
QCALIQSIKDKCPCC	COL6A3	2376	P12111
ICRCKKCPELSCSKI	CRIM1	561	Q9NZV1
KYVRCPCNCLLICKV	PIP4P1	121	Q86T03
PCNCLLICKVTSQRI	PIP4P1	126	Q86T03
RCVSILCCKFCKQVL	FAM72B	11	Q86X60
LLCCCCSMVSQKNKI	RFPL1	76	O75677
ICPKTCKNFLCLCSG	NKTR	31	P30414
VCCSCSPQKAKRIVL	SLC26A3	41	P40879
LCRKRCINQLLCKLP	SELENOP	276	P49908
CRCKNSNTVCCKVPT	SPRY2	291	O43597
NSPCISKGCAKQLCC	SLC30A10	401	Q6XR72
CQFCKRPVCSQCCKK	SPIRE1	611	Q08AE8
NQYIIKKCSPCCACL	SLC24A5	221	Q71RS6
PRCNKKCLCVHGTCN	STAB2	786	Q8WWQ8
CQQPCKRLLICSHKC	ZNFX1	1461	Q9P2E3
RCQTCKINLCLECQK	ZFYVE1	91	Q9HBF4
KCFCDRCCSQKVPLR	ZFYVE21	71	Q9BQ24
CCVIDKITRNQCQLC	THRA	96	P10827
CCQRLVELCKQCLLV	TTLL7	811	Q6ZT98
CQSCKQTRCSCPVKL	ZAR1	376	Q86SH2