Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	POMGNT1 SIAH2 ATG2A TEP1 MAP3K5 CCND3 FOCAD MTOR CSPG4 NLRC5 DOCK6 MED12 RAD9A PPP1R16A	3.03e-06	1105	99	14	35748872
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	UTP6 MYBBP1A NOL6 NOP58 GTF2H4 IGHMBP2 SCAPER MACF1 QARS1 MED12 EXOC4	1.10e-05	759	99	11	35915203
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SH3TC2 ERP44 PPFIA4 MORC2 SCAPER TBC1D12 MACF1 MED12 EXOC4	1.20e-05	493	99	9	15368895
Pubmed	Identification of two new members of the CSMD gene family.	CSMD3 CSMD1	2.40e-05	3	99	2	12906867
Pubmed	Reciprocal negative regulation of PDK1 and ASK1 signaling by direct interaction and phosphorylation.	PDPK1 MAP3K5	2.40e-05	3	99	2	19920149
Pubmed	mTOR regulates PRMT1 expression and mitochondrial mass through STAT1 phosphorylation in hepatic cell.	STAT1 MTOR	2.40e-05	3	99	2	33741434
Pubmed	ABCG2 shields against epilepsy, relieves oxidative stress and apoptosis via inhibiting the ISGylation of STAT1 and mTOR.	STAT1 MTOR	2.40e-05	3	99	2	38981367
Pubmed	Milk protein synthesis is regulated by T1R1/T1R3, a G protein-coupled taste receptor, through the mTOR pathway in the mouse mammary gland.	TAS1R3 MTOR	2.40e-05	3	99	2	28497545
Pubmed	Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.	MAP3K5 MTOR	2.40e-05	3	99	2	15218033
Pubmed	Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin.	STAT1 MTOR	2.40e-05	3	99	2	12807916
Pubmed	Differential Regulation of ERK1/2 and mTORC1 Through T1R1/T1R3 in MIN6 Cells.	TAS1R3 MTOR	4.79e-05	4	99	2	26168033
Pubmed	Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes.	CEBPA CCND3	4.79e-05	4	99	2	16537903
Pubmed	Polyphyllin I induces autophagy and cell cycle arrest via inhibiting PDK1/Akt/mTOR signal and downregulating cyclin B1 in human gastric carcinoma HGC-27 cells.	PDPK1 MTOR	4.79e-05	4	99	2	31387191
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	UTP6 MYBBP1A PDPK1 NOL6 ATG2A NOP58 QARS1 MED12	4.81e-05	454	99	8	33226137
Pubmed	Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease.	P3H3 CCND3 FOCAD CSPG4	7.50e-05	78	99	4	19204726
Pubmed	Erythropoietin enhances iron bioavailability in HepG2 cells by downregulating hepcidin through mTOR, C/EBPα and HIF-1α.	CEBPA MTOR	7.98e-05	5	99	2	39047915
Pubmed	Effect of advanced glycation end products on lectin-like oxidized low density lipoprotein receptor-1 expression in endothelial cells.	PDPK1 MTOR	7.98e-05	5	99	2	22863784
Pubmed	Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth.	PDPK1 MTOR	7.98e-05	5	99	2	26593251
Pubmed	Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals.	STAT1 MTOR	7.98e-05	5	99	2	15284440
Pubmed	Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube.	PDPK1 MTOR	7.98e-05	5	99	2	20004186
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	MYBBP1A CEBPA PDPK1 STAT1 CCND3 MTOR	8.33e-05	250	99	6	18660489
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	NOL6 SIAH2 ATG2A STAT1 MAP3K5 NOP58	9.69e-05	257	99	6	30945288
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	UTP6 MYBBP1A NOL6 NOP58 RNPEP MTOR MACF1 MED12 USP47	1.06e-04	653	99	9	22586326
Pubmed	PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.	PDPK1 MTOR	1.19e-04	6	99	2	23183047
Pubmed	NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells.	STAT1 NLRC5	1.19e-04	6	99	2	22412192
Pubmed	Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.	ROBO4 IGHMBP2	1.19e-04	6	99	2	19741192
Pubmed	Data in support of NFκB and JNK pathways involvement in TLR3-mediated HIV-1 transactivation, expression of IL-6 and transcription factors associated with HIV-1 replication.	CEBPA STAT1	1.19e-04	6	99	2	26862581
Pubmed	Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha.	PDPK1 MTOR	1.19e-04	6	99	2	11733037
Pubmed	Regulation of MHC Class I Expression in Lung Epithelial Cells during Inflammation.	STAT1 NLRC5	1.19e-04	6	99	2	35173036
Pubmed	Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1.	MAP3K5 QARS1	1.19e-04	6	99	2	11096076
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	MYBBP1A NOL6 MAP3K5 SLC25A3 NOP58 GTF2H4 NLRC5 TTC17	1.46e-04	533	99	8	30554943
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	MYBBP1A NOL6 DAD1 STAT1 SLC25A3 NOP58 GTF2H4 INTS2 CSPG4 QARS1 MED12 EXOC4	1.61e-04	1203	99	12	29180619
Pubmed	Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.	PDPK1 MTOR	1.67e-04	7	99	2	15718470
Pubmed	Activated α2-macroglobulin binding to cell surface GRP78 induces T-loop phosphorylation of Akt1 by PDK1 in association with Raptor.	PDPK1 MTOR	1.67e-04	7	99	2	24516643
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	UTP6 PDPK1 SCYL3 ATG2A STAT1 NOP58 MTOR TBC1D12 DOCK6 MED12 USP47	1.83e-04	1038	99	11	26673895
Pubmed	Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.	NLRC5 CSMD1 DOCK6	1.90e-04	39	99	3	21347282
Pubmed	Variations of chromosome 2 gene expressions among patients with lung cancer or non-cancer.	STAT1 TGFBRAP1	2.22e-04	8	99	2	27301951
Pubmed	ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection.	STAT1 MTOR	2.22e-04	8	99	2	35443177
Pubmed	Inactivation of mammalian target of rapamycin increases STAT1 nuclear content and transcriptional activity in alpha4- and protein phosphatase 2A-dependent fashion.	STAT1 MTOR	2.22e-04	8	99	2	19553685
Pubmed	IFN-λ Enhances Constitutive Expression of MHC Class I Molecules on Thymic Epithelial Cells.	STAT1 NLRC5	2.22e-04	8	99	2	32690660
Pubmed	Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems.	RTN2 RTN4RL2	2.22e-04	8	99	2	14664809
Pubmed	Functional proteomic analysis of human nucleolus.	UTP6 MYBBP1A NOL6 NOP58	2.46e-04	106	99	4	12429849
Pubmed	The role of Six1 in mammalian auditory system development.	HMX3 EYA1	2.85e-04	9	99	2	12874121
Pubmed	Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer.	PDPK1 MTOR	2.85e-04	9	99	2	21035469
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYBBP1A SLC25A3 MTOR TTC17 DOCK6	2.89e-04	202	99	5	33005030
Pubmed	Charcot-Marie-Tooth Hereditary Neuropathy Overview	SH3TC2 MORC2 IGHMBP2	3.53e-04	48	99	3	20301532
Pubmed	Visualization of biochemical networks in living cells.	PDPK1 MTOR	3.56e-04	10	99	2	11438723
Pubmed	A natural HIV p17 protein variant up-regulates the LMP-1 EBV oncoprotein and promotes the growth of EBV-infected B-lymphocytes: implications for EBV-driven lymphomagenesis in the HIV setting.	STAT1 CCND3	3.56e-04	10	99	2	25704763
Pubmed	Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.	PDPK1 STAT1 MTOR	4.22e-04	51	99	3	26764350
Pubmed	Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia.	ROBO4 CSPG4	4.34e-04	11	99	2	24355925
Pubmed	Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice.	HMX3 EYA1	4.34e-04	11	99	2	12642503
Pubmed	mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.	PDPK1 MTOR	4.34e-04	11	99	2	33052068
Pubmed	Small heterodimer partner SHP mediates liver X receptor (LXR)-dependent suppression of inflammatory signaling by promoting LXR SUMOylation specifically in astrocytes.	SIAH2 STAT1	4.34e-04	11	99	2	27485016
Pubmed	Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis.	CEBPA MED12	4.34e-04	11	99	2	12037571
Pubmed	Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear.	HMX3 EYA1	4.34e-04	11	99	2	16916509
Pubmed	USP7 controls NGN3 stability and pancreatic endocrine lineage development.	MYBBP1A SLC25A3 MACF1	6.16e-04	58	99	3	37117185
Pubmed	GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.	ROBO4 CCND3 CSPG4	6.48e-04	59	99	3	21421844
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	UTP6 CEBPA SLC25A3 NOP58 RNPEP	7.21e-04	247	99	5	32989298
Pubmed	Nucleolar maturation of the human small subunit processome.	UTP6 NOL6 NOP58	7.49e-04	62	99	3	34516797
Pubmed	Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.	ROBO4 CSPG4	8.22e-04	15	99	2	18345009
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	SLC25A3 NOP58 GTF2H4 QARS1	9.11e-04	150	99	4	30154076
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	UTP6 MYBBP1A NOL6 MORC2 SLC25A3 NOP58 MTOR EXOC4	9.21e-04	704	99	8	29955894
Pubmed	The embryonic expression pattern of 40 murine cDNAs homologous to Drosophila mutant genes (Dres): a comparative and topographic approach to predict gene function.	HMX3 EYA1	9.38e-04	16	99	2	9817915
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	CEBPA KLHL40 HMX3 RTN2 STAT1 GTF2H4 IGHMBP2 MACF1	9.64e-04	709	99	8	22988430
Pubmed	Six1 controls patterning of the mouse otic vesicle.	HMX3 EYA1	1.06e-03	17	99	2	14695375
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	LONP2 NOL6 ECT2L GPRC5C MORC2 STAT1 SLC25A3 GTF2H4 INTS2 IGHMBP2 MACF1 MED12	1.13e-03	1497	99	12	31527615
Pubmed	A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease.	SPTA1 MAP3K5	1.19e-03	18	99	2	16049941
Pubmed	Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios.	TEP1 CSMD1	1.33e-03	19	99	2	14671302
Pubmed	Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort.	ERP44 TGFBRAP1	1.33e-03	19	99	2	23551011
Pubmed	Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.	CEBPA CYP2J2 GTF2H4	1.35e-03	76	99	3	22323595
Pubmed	KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.	MTOR KICS2	1.47e-03	20	99	2	28199306
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	UTP6 MYBBP1A ERP44 DAD1 GPRC5C RTN2 MTOR QARS1 EXOC4	1.49e-03	942	99	9	31073040
Pubmed	Network organization of the human autophagy system.	ERP44 PDPK1 ATG2A MAP3K5 MTOR TGFBRAP1	1.59e-03	437	99	6	20562859
Pubmed	RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.	MMS22L SLC25A3	1.63e-03	21	99	2	21113133
Pubmed	Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.	DAD1 PPP1R16A	1.63e-03	21	99	2	21509594
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	UTP6 MYBBP1A NOL6 STAT1 SLC25A3 NOP58 GTF2H4 MACF1 QARS1 MED12 EXOC4	1.63e-03	1353	99	11	29467282
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	MYBBP1A RRM2B NOL6 GTF2H4 TBC1D12 QARS1	1.65e-03	440	99	6	34244565
Pubmed	Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.	STAT1 TGFBRAP1 MACF1 RAD9A	1.68e-03	177	99	4	22560297
Pubmed	An adhesion signaling axis involving Dystroglycan, β1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold.	NEDD9 CSPG4	1.79e-03	22	99	2	37540708
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	SPTA1 SLC25A3 MTOR TTC17 EXOC4	1.81e-03	304	99	5	32235678
Pubmed	Defining the membrane proteome of NK cells.	MYBBP1A LONP2 DAD1 SLC25A3 NOP58 INTS2 MTOR IGHMBP2 MED12 EXOC4	1.83e-03	1168	99	10	19946888
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CARMIL3 INTS2 USP47	1.87e-03	85	99	3	15449545
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	DAD1 RNPEP MTOR DOCK6	1.89e-03	183	99	4	31932471
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	MMS22L SLC25A3 GTF2H4 RNF6 MED12 RAD9A	1.91e-03	453	99	6	29656893
Pubmed	mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.	MTOR USP47	1.95e-03	23	99	2	22017875
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GALNS ERP44 P3H3 DAD1 POMGNT1 GCNT1 PRCP CSPG4 SCAPER TTC17	2.25e-03	1201	99	10	35696571
Pubmed	Rheb1 is required for mTORC1 and myelination in postnatal brain development.	MTOR CSPG4	2.31e-03	25	99	2	21238928
Pubmed	Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation.	SLC25A3 MACF1	2.31e-03	25	99	2	19405953
Pubmed	PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division.	CEBPA PDPK1	2.31e-03	25	99	2	27184845
Pubmed	A chemical tool for blue light-inducible proximity photo-crosslinking in live cells.	MTOR USP47	2.31e-03	25	99	2	35211260
Pubmed	The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival.	CEBPA PDPK1	2.49e-03	26	99	2	20685850
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	UTP6 MYBBP1A ERP44 NOL6 STAT1 SLC25A3 NOP58 MACF1 QARS1	2.61e-03	1024	99	9	24711643
Pubmed	MxA interacts with and is modified by the SUMOylation machinery.	KLHL35 SLC25A3	2.69e-03	27	99	2	25447205
Pubmed	Embryonic Steroids Control Developmental Programming of Energy Balance.	CEBPA SERPINA6	2.69e-03	27	99	2	34599818
Pubmed	Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.	MORC2 MACF1	2.69e-03	27	99	2	19026994
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	MMS22L MYBBP1A DAD1 INTS2 MTOR QARS1 EXOC4	2.77e-03	657	99	7	36180527
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CEBPA PPFIA4 TEP1 RNASE6 RNPEP PRCP	2.13e-06	167	100	6	d62d5dec30d006a9cc8f3bc5ccc578e10f105027
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CEBPA PPFIA4 TEP1 RNASE6 RNPEP PRCP	2.21e-06	168	100	6	3d8c431a3c8899383212fe6a7627889c40c5f3ef
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZCCHC24 CEBPA PPFIA4 GPRC5C TEP1 RTN2	2.53e-06	172	100	6	7fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZCCHC24 CEBPA PPFIA4 GPRC5C TEP1 RTN2	2.53e-06	172	100	6	2a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell	droplet-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 RNASE6 RNPEP PRCP	1.97e-05	146	100	5	ed932d43e9efd064ee4b49ddef529f3d041be765
ToppCell	droplet-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 RNASE6 RNPEP PRCP	1.97e-05	146	100	5	0d74962779055c774312d59fc3b1365163741c3a
ToppCell	IIF-Lymphocyte-T_NK-CD4_CTL\|IIF / Disease, Lineage and Cell Type	SIAH2 EYA1 CSMD3 ASIC4 RTN4RL2	2.97e-05	159	100	5	64e2b57e09bf25b2582f154375bb88cfd02a2521
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GALNS PPFIA4 SCYL3 STAT1 FBXO33	3.55e-05	165	100	5	354978d4f35154d7b2e36e94de669e045adef512
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CEBPA PPFIA4 SERPINA6 TEP1 RNASE6	3.76e-05	167	100	5	9526e2c7673d569d04e0728a2526318e67432e0a
ToppCell	droplet-Lung-nan-21m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 SERPINA6 RNASE6 PRCP	4.09e-05	170	100	5	71c52fadecc6b4bfe98692b266adaa1406f6d56d
ToppCell	droplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 SERPINA6 TEP1 RNASE6	4.09e-05	170	100	5	d72eb77271d61e27a3d247149561c7f45fadb28b
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MMS22L MYBBP1A APOBEC2 IGHMBP2 NLRC5	4.09e-05	170	100	5	070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell	droplet-Lung-nan-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 TEP1 RNPEP PRCP	4.32e-05	172	100	5	35d09640d5b04fa0bbb1b40d4b8f97da587a5046
ToppCell	droplet-Lung-nan-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 TEP1 RNPEP PRCP	4.32e-05	172	100	5	98cb64e2a768908105701a7a5b58f336036250fd
ToppCell	droplet-Lung-nan-21m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 TEP1 RNASE6 PRCP	4.45e-05	173	100	5	9019049b1e2a24cb0bbbc620d64ef29dd18cc4c6
ToppCell	droplet-Lung-nan-21m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 TEP1 RNASE6 PRCP	4.45e-05	173	100	5	077029eecfe636a5baf5f70464e1713b3f6b4274
ToppCell	droplet-Marrow-nan-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 GPRC5C AASDH TEP1 RNASE6	4.45e-05	173	100	5	6d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCell	Immune_cells-Monocytes\|Immune_cells / Lineage and Cell class	CEBPA PPFIA4 TEP1 RNASE6 RNPEP	4.45e-05	173	100	5	3eced40a65453a023a1673658592e7e2a099119b
ToppCell	facs-Spleen-nan-24m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC30A8 SIAH2 SLC25A3 RNASE6 APOBEC2	4.57e-05	174	100	5	a0641908ab6feaca5cd07142d7429983a2f68668
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CEBPA PPFIA4 TEP1 RNASE6 PRCP	4.82e-05	176	100	5	7d1e2627d7ec5ddd6c87c55d2a6879255b76949e
ToppCell	droplet-Marrow-nan-21m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA PPFIA4 TEP1 RNASE6 PRCP	4.96e-05	177	100	5	b860013f1fd397400a62d66ab521cfc81349ffe2
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 GIMAP5 GPRC5C CSPG4 DOCK6	5.09e-05	178	100	5	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	wk_08-11-Hematologic-Meg-ery-Primitive_erythrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SPTA1 SIAH2 CCND3 SPDYC ASIC4	5.23e-05	179	100	5	3c8046f43da5a02fa4278a7175b9cd8cf95b8e27
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CEBPA PPFIA4 TEP1 RNPEP PRCP	5.23e-05	179	100	5	fa58fa0901eadb170e3d2facb2a3d8c5e624329a
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	TTC16 ODAD1 ECT2L EYA1 ADGB	5.66e-05	182	100	5	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	Tuft-tuft-2\|World / Class top	P3H3 GIMAP5 TAS1R3 PPFIA4 HMX3	6.43e-05	187	100	5	4ec6eee866619dfe13c84f5d2e812bb380d37139
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 TTC16 EYA1 DOCK6 RAI2	6.76e-05	189	100	5	1137583e21d874c201c20581ba1995e2bfa3de59
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 TTC16 EYA1 DOCK6 RAI2	6.93e-05	190	100	5	7068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PDE1B GCNT1 TEP1 MAP3K5 IGHMBP2	6.93e-05	190	100	5	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-conventional_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SLC25A3 IDO2 RNASE6 PRCP PPP1R16A	7.83e-05	195	100	5	0fcc41cda3e5f921748cf7e7fe48dd7ca1de4636
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SH3TC2 CYP2J2 CSMD3 IDO2 CSMD1	8.42e-05	198	100	5	a54ae5275a510b49d7629f0908817a0c5f05020e
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SH3TC2 CYP2J2 CSMD3 IDO2 CSMD1	8.42e-05	198	100	5	34997e3896d0893fbe51bfb0d4660ccaca1c975e
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SH3TC2 CYP2J2 CSMD3 IDO2 CSMD1	8.42e-05	198	100	5	686eda427b075e788de38149eae82faf19bd5704
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	CYP2J2 GIMAP5 STAT1 NLRC5 MACF1	8.42e-05	198	100	5	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ROBO4 NEDD9 PRCP MACF1 DOCK6	8.83e-05	200	100	5	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	ECT2L STAT1 CCND3 MTOR	2.73e-05	53	96	4	C1961099
Disease	insulin resistance	SLC30A8 EYA1 MTOR CSMD1	4.17e-05	59	96	4	EFO_0002614
Disease	TEMPS-A questionnaire	SLC30A8 EYA1 CSMD1	7.29e-05	25	96	3	EFO_0004783
Disease	schizophrenia (implicated_via_orthology)	AVPR1A CSMD3 MTOR CSMD1	7.30e-05	68	96	4	DOID:5419 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth disease	SH3TC2 MORC2 IGHMBP2	3.49e-04	42	96	3	cv:C0007959
Disease	myocardial infarction (implicated_via_orthology)	AVPR1A MAP3K5 MTOR	1.32e-03	66	96	3	DOID:5844 (implicated_via_orthology)
Disease	triacylglycerol 48:3 measurement	CACNA2D4 CSMD1	2.32e-03	22	96	2	EFO_0010406

Protein segments in the cluster

Peptide	Gene	Start	Entry
NLEEADAFIAFANLL	TBC1D12	601	O60347
RIFAFDHDLFSFADL	TMEM62	291	Q0P6H9
ADFLLSSELATEVHF	ARMT1	266	Q9H993
RASNLHDLLAALDAF	SLC4A9	301	Q96Q91
DLAAVIAHDFLAFIL	CCND3	151	P30281
ASASNFRAFELLHLH	RNPEP	26	Q9H4A4
FLNFSTEANHDFLEI	CSMD1	2016	Q96PZ7
QFLAFDTEASHDILR	CSMD3	1456	Q7Z407
LASAASFFGENHLEV	CSPG4	26	Q6UVK1
DLAANEKAVHADFFN	COPS9	31	Q8WXC6
ETHFISLLNAIDALF	NEDD9	716	Q14511
FHEENLICSTLDLFF	CYP2J2	296	P51589
FDLFSANEHLLCSEL	ADGB	121	Q8N7X0
HDLSLFLFNDALLVS	ECT2L	811	Q008S8
AASELSNFLLLHCDF	AASDH	41	Q4L235
AKDLDFINLLSFDFH	CHI3L2	201	Q15782
LDIFLHNSNATFDLI	CC2D2B	1131	Q6DHV5
HSELALDLANFQADV	ATG2A	581	Q2TAZ0
AAHAEEAFFNTILPA	APOBEC2	96	Q9Y235
HELFPDFAALAALAL	C17orf113	591	A0A1B0GUU1
SLLHLQDDLFADLAN	RTN4RL2	166	Q86UN3
QDDLFADLANLSHLF	RTN4RL2	171	Q86UN3
IFQEDAALDLSVAAH	RAI2	336	Q9Y5P3
LSFAESANLNLSIHF	RAD9A	226	Q99638
DLAAAAAHTFFVANP	P3H3	171	Q8IVL6
HFEKFQDTAEALAAF	NOP58	46	Q9Y2X3
ERAFADFLFASTILH	DAD1	91	P61803
LAASASAEFFADIAL	SLC25A3	166	Q00325
AFGSFDLLDNTDIHL	LONP2	716	Q86WA8
EHRALLNAFTATFEL	LCN12	56	Q6JVE5
FSQLADAAADFTLLA	MMS22L	736	Q6ZRQ5
LAAELEAANLSHAAA	HMX3	286	A6NHT5
ALLALDENFDHNTLA	PPFIA4	1061	O75335
FNLLDFSHLESRDLA	CARMIL3	191	Q8ND23
VNLHSLALDFCDFTA	FBXO33	306	Q7Z6M2
AAQSTVLHAFDEFLG	IDO2	281	Q6ZQW0
FDVFSLNQAADDHAL	PDE1B	166	Q01064
IFNLADTHLFFNDLE	EYA1	366	Q99502
ALLSVDFHALEQDAS	INTS2	86	Q9H0H0
FADESLDLVAAALFL	NOL6	871	Q9H6R4
HLNFLTSEQALADFA	PRCP	141	P42785
DLSFHDSLATFVAIL	MED12	1121	Q93074
LDEASVQDLFAAAHR	KLHL40	96	Q2TBA0
LNLVAADFLFLSGHI	MRGPRX3	66	Q96LB0
SALSDADIFHLANLT	ASIC4	126	Q96FT7
FLAEALTLGQFDHSH	EPHA10	691	Q5JZY3
AFLHAQSFTSLADAA	ODAD1	426	Q96M63
AFTHLSLQEFLAALH	NLRC5	511	Q86WI3
DALAFDIQFFISEHA	MACF1	3546	Q9UPN3
HSAEARAAAFQHLLL	MYBBP1A	586	Q9BQG0
HEFLFGALAELVDNA	MORC2	26	Q9Y6X9
GSFHSNDLFLDAQLL	GIMAP5	216	Q96F15
FSCLAAHVFALNFLA	GPRC5C	131	Q9NQ84
DSHFISFLNEVSLAL	KICS2	416	Q96MD2
LCTLLSHDFFRNDFL	SCYL3	236	Q8IZE3
ESANHLCLLDTAFFV	PLA2G4E	691	Q3MJ16
LLQDLHVADNTFVFF	GALNS	271	P34059
FDKFNAVAAAHSVVL	EXOC4	346	Q96A65
DVELAEHLNASLAFF	DOCK6	986	Q96HP0
EHLNASLAFFLSDLL	DOCK6	991	Q96HP0
VELGAEFLLESNAHF	CACNA2D4	181	Q7Z3S7
AAFNDEFLADLFQHS	CEBPA	71	P49715
VANILHDDCAFLSAF	ERP44	181	Q9BS26
TFSLQVDADFELHNF	DDI2	16	Q5TDH0
HLFANKFDVDVDLFA	GCNT1	396	Q02742
AIQSLRFFNSFAALH	SCAPER	1216	Q9BY12
HRGLASANVDFAFSL	SERPINA6	36	P08185
FHNTALDKALDFFLL	FOCAD	1661	Q5VW36
LASLDERFDAHLAQA	MTOR	676	P42345
AVLLLAAGHQFESSF	MAP3K5	436	Q99683
SAATQLRHFFLVEDL	RTN2	441	O75298
FLSDLNLASLHVVDA	QARS1	711	P47897
AEFHVSLLSIAQLFD	UTP6	236	Q9NYH9
DANFTAAAHSALEDV	RGMB	381	Q6NW40
HADFSSFLLLVDAAV	TGIF2LX	211	Q8IUE1
AANDVSFATIRFHDL	STAT1	46	P42224
IHDLDSNSFELDLQF	PDPK1	416	O15530
DFFSFLSQSIHLLEE	POMGNT1	401	Q8WZA1
LHVAAANGFSEAAAL	PPP1R16A	236	Q96I34
LRLAHFFLLNESDDD	RNF6	586	Q9Y252
CLVFDTAIAHLFADN	SIAH2	296	O43255
DAHDATEYFLLALAA	SH3TC2	1226	Q8TF17
FLHDSFQNVAAVCDL	RNASE6	66	Q93091
LADAHFARALAVAVD	ROBO4	901	Q8WZ75
QFLSQVDFELLLAHA	GTF2H4	411	Q92759
HILAFFAASDGIVNE	RRM2B	91	Q7LG56
AAVDLLNRHATEFDA	TGFBRAP1	736	Q8WUH2
AAFVHALGDLFQSIS	SLC30A8	216	Q8IWU4
VLLFASVHAAHALFN	TAS1R3	271	Q7RTX0
FDLAADVLAENAHLI	TTC30B	336	Q8N4P2
FLNAHDAIDALEAQL	TEP1	566	Q99973
VAFDESHDFQLSLDR	IGHMBP2	116	P38935
HQEVQAFLSLLEDSF	SPDYC	56	Q5MJ68
SSQAFASVEEALHAF	USP47	336	Q96K76
AEDLFVEFAHKASAL	SPTA1	2041	P02549
HDALEFFNSLVDSLD	USP9Y	1686	O00507
EGTFFSLLAALHAAQ	UNQ9370/PRO34162	61	Q6UXP9
AAVVVHAALDDSDFF	TTC17	281	Q96AE7
RHLSLADLAVAFFQV	AVPR1A	91	P37288
FDLAADVLAENAHLT	TTC30A	336	Q86WT1
AFLDALNVFSHAAEL	TTC16	151	Q8NEE8
AQLHFLFLREDTAGA	TSPEAR	126	Q8WU66
LSLQDTHQASAFDAF	ZCCHC24	26	Q8N2G6
FSFDVHDDVRLLSDA	FAM50B	266	Q9Y247
AFAEVARHADFLELA	KLHL35	181	Q6PF15