Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

ABCC3 SLC35B3 SLC52A3 SLC6A6 SLC10A1 SLCO1C1 SLC17A9 SLC5A12 SLC5A8 SLC39A14 SLC52A2 SLC37A4

8.00e-0729313612GO:0008514
GeneOntologyMolecularFunctionprotein serine kinase activity

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

1.24e-0636313613GO:0106310
GeneOntologyMolecularFunctionmonocarboxylate:sodium symporter activity

SLC6A6 SLC10A1 SLC5A12 SLC5A8

2.65e-06151364GO:0140161
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCC3 SLC22A23 SLC35B3 PKDREJ SLC9C2 ABCA8 ABCC6 SLC52A3 SLC30A7 SLC6A6 GJA4 SLC10A1 SLCO1C1 NALCN SLC17A9 SLC35E3 SLC5A12 SLC5A8 SLC39A14 SLC52A2 TMC5 SLC37A4 VDAC2

4.62e-06118013623GO:0022857
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC3 SLC35B3 SLC9C2 ABCA8 ABCC6 SLC6A6 SLC10A1 SLCO1C1 SLC17A9 SLC35E3 SLC5A12 SLC5A8 SLC39A14 SLC37A4

4.85e-0647713614GO:0022804
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC35B3 SLC9C2 SLC6A6 SLC10A1 SLCO1C1 SLC17A9 SLC35E3 SLC5A12 SLC5A8 SLC39A14 SLC37A4

5.95e-0629613611GO:0015291
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC6A6 SLC10A1 SLC5A12 SLC5A8

7.37e-06191364GO:0015355
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

TH AGMO PAH

1.06e-0571363GO:0016714
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

1.16e-0544613613GO:0004674
GeneOntologyMolecularFunctiontransporter activity

ABCC3 SLC22A23 SLC35B3 PKDREJ SLC9C2 ABCA8 ABCC6 SLC52A3 SLC30A7 SLC6A6 GJA4 SLC10A1 SLCO1C1 NALCN SLC17A9 SLC35E3 SLC5A12 SLC5A8 SLC39A14 SLC52A2 TMC5 SLC37A4 VDAC2

1.93e-05128913623GO:0005215
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

ABCC3 SLC6A6 SLC10A1 SLCO1C1 SLC5A12 SLC5A8

3.48e-05901366GO:0008028
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

ABCC3 SLC35B3 SLC17A9 SLC35E3 SLC37A4

5.07e-05591365GO:1901505
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC6A6 SLC10A1 SLC5A12 SLC5A8

9.15e-05351364GO:0005343
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

ABCC3 SLC10A1 SLCO1C1 SLC5A12 SLC5A8

1.16e-04701365GO:1901618
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC3 ABCA8 ABCC6

1.32e-04151363GO:0008559
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDK8 CAMKK1 NEK10 POLE2 POLR2B CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 SHPK DSTYK UBA6 ULK1 MAPK3 CDK2

2.19e-0493813617GO:0016772
GeneOntologyMolecularFunctionprotein kinase activity

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

2.36e-0460013613GO:0004672
GeneOntologyMolecularFunctiongalanin receptor activity

GALR3 GALR2

2.74e-0441362GO:0004966
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 SHPK DSTYK ULK1 MAPK3 CDK2

3.48e-0470913614GO:0016773
GeneOntologyMolecularFunctionlactate transmembrane transporter activity

SLC5A12 SLC5A8

6.78e-0461362GO:0015129
GeneOntologyMolecularFunctionriboflavin transmembrane transporter activity

SLC52A3 SLC52A2

6.78e-0461362GO:0032217
GeneOntologyMolecularFunctionkinase activity

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 SHPK DSTYK ULK1 MAPK3 CDK2

7.28e-0476413614GO:0016301
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC3 SLC35B3 ABCC6 SLC6A6

7.95e-04611364GO:1901682
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase activity

CDK8 CDK19 CDK2

1.10e-03301363GO:0004693
GeneOntologyMolecularFunctioncyclin-dependent protein kinase activity

CDK8 CDK19 CDK2

1.10e-03301363GO:0097472
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9C2 SLC6A6 SLC10A1 NALCN SLC5A12 SLC5A8

1.13e-031711366GO:0015081
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC3 ABCC6

1.26e-0381362GO:0015431
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A6 SLC10A1 SLC5A12 SLC5A8 SLC39A14

1.34e-031191365GO:0015294
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC3 SLC10A1 SLCO1C1 SLC5A8

1.56e-03731364GO:0170055
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

ABCC3 SLC10A1 SLCO1C1

1.58e-03341363GO:0015125
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC3 ABCA8 ABCC6

1.58e-03341363GO:0042910
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC3 ABCC6

2.00e-03101362GO:0043225
GeneOntologyMolecularFunctionoxygen binding

CYP26A1 ADGB TH

2.03e-03371363GO:0019825
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A6 SLC10A1 SLC5A12 SLC5A8

2.28e-03811364GO:0015370
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC35B3 SLC17A9 SLC37A4

2.36e-03391363GO:0015605
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

TAAR5 ADRA2A HRH3

2.73e-03411363GO:0008227
GeneOntologyMolecularFunctionG protein-coupled receptor activity

ADGRG5 GALR3 GPR82 ADGRB3 TAAR5 OR5M3 GALR2 OR2C1 ADRA2A ADGRF3 OR52B6 HRH3 S1PR4 OR5D13

2.85e-0388413614GO:0004930
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCC3 SLC6A6 SLC10A1 SLCO1C1 SLC5A12 SLC5A8

2.97e-032071366GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCC3 SLC6A6 SLC10A1 SLCO1C1 SLC5A12 SLC5A8

3.04e-032081366GO:0005342
GeneOntologyMolecularFunctioncatecholamine binding

TH ADRA2A

3.42e-03131362GO:1901338
GeneOntologyMolecularFunctionsymporter activity

SLC6A6 SLC10A1 SLC5A12 SLC5A8 SLC39A14

3.66e-031501365GO:0015293
GeneOntologyBiologicalProcessorganic anion transport

ABCC3 SLC35B3 ABCC6 SLC52A3 SLC6A6 SLC10A1 SLCO1C1 SLC17A9 SLC5A12 SLC5A8 SLC39A14 SLC52A2 SLC37A4 HRH3

6.77e-0651513414GO:0015711
GeneOntologyBiologicalProcesscarbohydrate derivative transport

ABCC3 SLC35B3 ABCC6 SLC17A9 SLC35E3 SLC37A4

3.86e-05961346GO:1901264
GeneOntologyBiologicalProcessgalanin-activated signaling pathway

GALR3 GALR2

4.19e-0521342GO:0090663
GeneOntologyBiologicalProcessmonoatomic ion transport

ABCC3 SLC22A23 NDFIP2 PKDREJ SLC9C2 GALR2 ABCC6 SLC30A7 SPTBN4 SLC6A6 GJA4 ADRA2A SLC10A1 SLCO1C1 NALCN SLC5A12 SLC5A8 SLC39A14 TMC5 HRH3 CDK2 VDAC2

7.42e-05137413422GO:0006811
GeneOntologyCellularComponentCKM complex

CDK8 CDK19 MED12

2.67e-0651363GO:1990508
GeneOntologyCellularComponentbasal part of cell

ABCC3 CLDN7 ABCA8 ABCC6 SLC6A6 AURKA ADRA2A SLC10A1 SLCO1C1 PRCP DSTYK SLC39A14

6.96e-0637813612GO:0045178
GeneOntologyCellularComponentbasolateral plasma membrane

ABCC3 CLDN7 ABCA8 ABCC6 SLC6A6 AURKA ADRA2A SLC10A1 SLCO1C1 DSTYK SLC39A14

8.11e-0632013611GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

ABCC3 CLDN7 ABCA8 ABCC6 SLC6A6 AURKA ADRA2A SLC10A1 SLCO1C1 DSTYK SLC39A14

2.08e-0535413611GO:0009925
GeneOntologyCellularComponentlate endosome

NDFIP2 CD1E YIPF2 FIG4 NEGR1 IGHG2 SCARB2 MAPK3 SLC39A14 UVRAG

9.56e-0534813610GO:0005770
GeneOntologyCellularComponentprotein kinase complex

CDK8 NEK10 CDK19 ULK1 UVRAG MED12 CDK2

1.26e-041701367GO:1902911
GeneOntologyCellularComponentnuclear cyclin-dependent protein kinase holoenzyme complex

CDK8 CDK19 MED12

2.05e-04181363GO:0019908
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

CDK8 NEK10 POLE2 POLR2B CDK19 ULK1 UVRAG MED12 CDK2

3.53e-043351369GO:0061695
GeneOntologyCellularComponentserine/threonine protein kinase complex

CDK8 CDK19 ULK1 UVRAG MED12 CDK2

5.74e-041571366GO:1902554
GeneOntologyCellularComponentcyclin-dependent protein kinase holoenzyme complex

CDK8 CDK19 MED12 CDK2

6.71e-04611364GO:0000307
GeneOntologyCellularComponentaxon hillock

SPTBN4 AURKA

1.47e-0391362GO:0043203
DomainS_TKc

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

2.09e-0635913513SM00220
DomainProtein_kinase_ATP_BS

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

3.78e-0637913513IPR017441
DomainPkinase

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

4.00e-0638113513PF00069
DomainSer/Thr_kinase_AS

CDK8 CAMKK1 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

1.11e-0535713512IPR008271
DomainPROTEIN_KINASE_ST

CDK8 CAMKK1 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

1.28e-0536213512PS00108
DomainPROTEIN_KINASE_ATP

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

2.90e-0545913513PS00107
DomainProt_kinase_dom

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

5.55e-0548913513IPR000719
DomainPROTEIN_KINASE_DOM

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

6.03e-0549313513PS50011
DomainGPS

ADGRG5 ADGRB3 PKDREJ ADGRF3

1.02e-04341354SM00303
DomainGPS

ADGRG5 ADGRB3 PKDREJ ADGRF3

1.43e-04371354IPR000203
DomainRiboflavin_transptr

SLC52A3 SLC52A2

1.55e-0431352IPR009357
DomainDUF1011

SLC52A3 SLC52A2

1.55e-0431352PF06237
DomainGalanin_rcpt

GALR3 GALR2

1.55e-0431352IPR000405
DomainKinase-like_dom

CDK8 CAMKK1 NEK10 CDK19 MAP3K6 MKNK1 AURKA TLK1 MAP4K1 DSTYK ULK1 MAPK3 CDK2

1.55e-0454213513IPR011009
DomainBiopterin_H

TH PAH

3.08e-0441352PF00351
DomainMultidrug-R_assoc

ABCC3 ABCC6

3.08e-0441352IPR005292
Domain-

TH PAH

3.08e-04413521.10.800.10
DomainTyrosine_3-monooxygenase-like

TH PAH

3.08e-0441352IPR019773
DomainAromatic-AA_hydroxylase_C

TH PAH

3.08e-0441352IPR019774
DomainArAA_hydroxylase_Fe/CU_BS

TH PAH

3.08e-0441352IPR018301
DomainBH4_AAA_HYDROXYL_2

TH PAH

3.08e-0441352PS51410
DomainArAA_hydroxylase

TH PAH

3.08e-0441352IPR001273
DomainBH4_AAA_HYDROXYL_1

TH PAH

3.08e-0441352PS00367
DomainMFS

SLC22A23 MFSD6 SLCO1C1 SLC17A9 SLC37A4

1.13e-031081355PS50850
DomainCa/CaM-dep_Ca-dep_prot_Kinase

CAMKK1 MKNK1 AURKA ULK1

1.57e-03691354IPR020636
Pubmed

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.

CDK8 CDK19 TOPBP1 MED12

1.64e-088138430695077
Pubmed

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.

CDK8 CDK19 MED12

2.44e-074138329440396
Pubmed

Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.

CDK8 CDK19 MED12

3.37e-068138323749998
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

NAT14 TBC1D15 NPTX1 ERO1B ELOVL5 TTC27 POR SLC30A7 TLE1 MRPS15 LIMCH1 MAPK3 SLC39A14

1.04e-057541381333060197
Pubmed

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.

CDK8 CDK19 MED12

1.31e-0512138323563140
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

ADGRB3 ELFN2 ELMO1 ARFGEF3 SLC6A6 SLCO1C1 MAPK3

1.46e-05197138736604605
Pubmed

Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.

UBA6 UBE2Z

1.56e-052138235970836
Pubmed

Localization of the human tyrosine hydroxylase gene to 11p15: gene duplication and evolution of metabolic pathways.

TH PAH

1.56e-05213822872999
Pubmed

Effects of galanin receptor 2 and receptor 3 knockout in mouse models of acute seizures.

GALR3 GALR2

1.56e-052138230298565
Pubmed

Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.

CDK8 CDK19

1.56e-052138235181333
Pubmed

Regulatory functions of the Mediator kinases CDK8 and CDK19.

CDK8 CDK19

1.56e-052138230585107
Pubmed

HIV Transcription Is Independent of Mediator Kinases.

CDK8 CDK19

1.56e-052138231044597
Pubmed

An update on the genetics, clinical presentation, and pathomechanisms of human riboflavin transporter deficiency.

SLC52A3 SLC52A2

1.56e-052138230793323
Pubmed

Alpha-2 adrenergic stimulation triggers Achilles tenocyte hypercellularity: Comparison between two model systems.

TH ADRA2A

1.56e-052138222292987
Pubmed

Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection.

CDK8 CDK19

1.56e-052138232560467
Pubmed

Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.

SLC52A3 SLC52A2

1.56e-052138229053833
Pubmed

The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons.

ADGRB3 ELMO1

1.56e-052138223628982
Pubmed

[Mechanisms of transcriptional regulation upon protein phosphorylation by mediator complexes].

CDK8 CDK19

1.56e-052138220408451
Pubmed

Expression of the sodium-coupled monocarboxylate transporters SMCT1 (SLC5A8) and SMCT2 (SLC5A12) in retina.

SLC5A12 SLC5A8

1.56e-052138217591909
Pubmed

Inhibition of Cdk2 activity decreases Aurora-A kinase centrosomal localization and prevents centrosome amplification in breast cancer cells.

AURKA CDK2

1.56e-052138223446853
Pubmed

Galanin and its three receptors in human pituitary adenoma.

GALR3 GALR2

1.56e-052138222889491
Pubmed

A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.

CDK8 MED12

1.56e-052138231988137
Pubmed

Mediator kinase inhibition further activates super-enhancer-associated genes in AML.

CDK8 CDK19

1.56e-052138226416749
Pubmed

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

CDK8 CDK19

1.56e-052138228855340
Pubmed

Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.

CDK8 CDK19

1.56e-052138227678455
Pubmed

Involvement of Neuropeptide Galanin Receptors 2 and 3 in Learning, Memory and Anxiety in Aging Mice.

GALR3 GALR2

1.56e-052138233915732
Pubmed

CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.

CDK8 CDK19

1.56e-052138236006697
Pubmed

CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.

CDK8 CDK19

1.56e-052138237378433
Pubmed

Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney.

SLC5A12 SLC5A8

1.56e-052138217692818
Pubmed

Cell Cycle-Dependent Switch of TopBP1 Functions by Cdk2 and Akt.

TOPBP1 CDK2

1.56e-052138231964753
Pubmed

Elevated expression of galanin receptors in childhood neuroblastic tumors.

GALR3 GALR2

1.56e-052138211867941
Pubmed

Galanin receptor 3 attenuates inflammation and influences the gut microbiota in an experimental murine colitis model.

GALR3 GALR2

1.56e-052138233436730
Pubmed

Alpha-2A adrenergic receptor gene variants are associated with increased intra-individual variability in response time.

TH ADRA2A

1.56e-052138224166412
Pubmed

Exploring the molecular structures that confer ligand selectivity for galanin type II and III receptors.

GALR3 GALR2

1.56e-052138232231393
Pubmed

Identification of target genes for the CDK subunits of the Mediator complex.

CDK8 CDK19

1.56e-052138222117896
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCC3 NAT14 NPTX1 ERO1B B3GALNT2 ELOVL5 SLC30A7 SLC6A6 NEGR1 PRCP SCARB2 CERCAM SLC39A14 POFUT2 TAPBP SLC37A4

2.39e-0512011381635696571
Pubmed

A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.

CDK8 POLR2B CDK19 MED12

3.71e-0547138415175163
Pubmed

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.

CDK8 MED12 CDK2

3.99e-0517138316109376
Pubmed

SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation.

SLC52A3 SLC52A2

4.68e-053138226976849
Pubmed

Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.

CDK8 CDK19

4.68e-053138226002960
Pubmed

The Expression of Riboflavin Transporters in Human Colorectal Cancer.

SLC52A3 SLC52A2

4.68e-053138229715086
Pubmed

Riboflavin Transporter Deficiency

SLC52A3 SLC52A2

4.68e-053138226072523
Pubmed

Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis.

POR IL23R

4.68e-053138232826979
Pubmed

Novel riboflavin transporter family RFVT/SLC52: identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52.

SLC52A3 SLC52A2

4.68e-053138223506902
Pubmed

Single nucleotide polymorphisms in ADAM17, IL23R and SLCO1C1 genes protect against infliximab failure in adults with Crohn's disease.

SLCO1C1 IL23R

4.68e-053138236621146
Pubmed

Palmitate and Nitric Oxide Regulate the Expression of Spexin and Galanin Receptors 2 and 3 in Hypothalamic Neurons.

GALR3 GALR2

4.68e-053138231730796
Pubmed

c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney.

SLC5A12 SLC5A8

4.68e-053138216873376
Pubmed

Mediator kinase module and human tumorigenesis.

CDK8 MED12

4.68e-053138226182352
Pubmed

Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3.

GALR3 GALR2

4.68e-05313829832121
Pubmed

Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9.

CDK8 CDK19

4.68e-053138228151579
Pubmed

MED12 interacts with the heat-shock transcription factor HSF1 and recruits CDK8 to promote the heat-shock response in mammalian cells.

CDK8 MED12

4.68e-053138234056708
Pubmed

Madras motor neuron disease (MMND) is distinct from the riboflavin transporter genetic defects that cause Brown-Vialetto-Van Laere syndrome.

SLC52A3 SLC52A2

4.68e-053138224139842
Pubmed

MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis.

ULK1 MAPK3

4.68e-053138233213267
Pubmed

Induction of viral, 7-methyl-guanosine cap-independent translation and oncolysis by mitogen-activated protein kinase-interacting kinase-mediated effects on the serine/arginine-rich protein kinase.

MKNK1 MAPK3

4.68e-053138225187541
Pubmed

Role of hepatic transporters in prevention of bile acid toxicity after partial hepatectomy in mice.

ABCC3 SLC10A1

4.68e-053138219497955
Pubmed

Different stabilities and denaturation pathways for structurally related aromatic amino acid hydroxylases.

TH PAH

4.68e-053138215135070
Pubmed

Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.

ABCC3 ABCC6

4.68e-053138217845218
Pubmed

Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12).

SLC5A12 SLC5A8

4.68e-053138230604288
Pubmed

POLE2 facilitates the malignant phenotypes of glioblastoma through promoting AURKA-mediated stabilization of FOXM1.

POLE2 AURKA

4.68e-053138235039475
Pubmed

BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1.

MKNK1 MAPK3

4.68e-053138225609615
Pubmed

Galanin Receptors (GalR1, GalR2, and GalR3) Expression in Colorectal Cancer Tissue and Correlations to the Overall Survival and Poor Prognosis of CRC Patients.

GALR3 GALR2

4.68e-053138235409094
Pubmed

ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ.

TH MAPK3

4.68e-05313821347949
Pubmed

Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain.

SLC52A3 SLC52A2

4.68e-053138220463145
Pubmed

Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion.

WNT11 CLDN7 MAPK3

7.71e-0521138324603431
Pubmed

The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.

ABCC6 MAPK3

9.33e-054138220463007
Pubmed

Sphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cells.

MAPK3 S1PR4

9.33e-054138220837468
Pubmed

A novel arylbenzofuran induces cervical cancer cell apoptosis and G1/S arrest through ERK-mediated Cdk2/cyclin-A signaling pathway.

MAPK3 CDK2

9.33e-054138227259234
Pubmed

The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons.

GALR3 GALR2

9.33e-054138212533601
Pubmed

The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator.

CDK8 MED12

9.33e-054138219047373
Pubmed

G-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates.

ADGRB3 ELMO1

9.33e-054138224567399
Pubmed

Alcoholism is associated with GALR3 but not two other galanin receptor genes.

GALR3 GALR2

9.33e-054138217083333
Pubmed

NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells.

CDK8 TBC1D15

9.33e-054138238409448
Pubmed

Cdk8 is required for establishment of H3K27me3 and gene repression by Xist and mouse development.

CDK8 CDK19

9.33e-054138232439758
Pubmed

Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1.

UBA6 UBE2Z

9.33e-054138224528925
Pubmed

Association of genetic polymorphisms in AURKA, BRCA1, CCNE1 and CDK2 with the risk of endometrial carcinoma and clinicopathological parameters among Chinese Han women.

AURKA CDK2

9.33e-054138225463638
Pubmed

Genetic polymorphisms in AURKA, BRCA1, CCNE1 and CDK2 are associated with ovarian cancer susceptibility among Chinese Han women.

AURKA CDK2

9.33e-054138223787073
Pubmed

Brain galanin system genes interact with life stresses in depression-related phenotypes.

GALR3 GALR2

9.33e-054138224706871
Pubmed

Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system.

UBA6 UBE2Z

9.33e-054138223499007
Pubmed

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.

CDK8 POLR2B MED12

1.32e-0425138319240132
Pubmed

Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway.

AURKA MAPK3

1.55e-045138227152455
Pubmed

Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galanin receptor type II and III.

GALR3 GALR2

1.55e-045138224517231
Pubmed

LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6.

UBA6 UBE2Z

1.55e-045138227569286
Pubmed

A role for PML3 in centrosome duplication and genome stability.

AURKA CDK2

1.55e-045138215749021
Pubmed

Gastrointestinal factors influencing zinc absorption and homeostasis.

SLC30A7 SLC39A14

1.55e-045138221462106
Pubmed

CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium.

CDK8 CDK19

1.55e-045138236545778
Pubmed

Tousled-like kinase in a microbial eukaryote regulates spindle assembly and S-phase progression by interacting with Aurora kinase and chromatin assembly factors.

AURKA TLK1

1.55e-045138217940067
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

POLR2B ALDH1L1 GTF3C4 ASS1 UBA6 LIMCH1 ADGRF3 TAPBP MED12

1.74e-04497138936774506
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRG5 ADGRB3 ADGRF3

2.07e-0429138315203201
Pubmed

Human mediator subunit MED26 functions as a docking site for transcription elongation factors.

CDK8 POLR2B CDK19 MED12

2.09e-0473138421729782
Pubmed

Galanin promotes neuronal differentiation from neural progenitor cells in vitro and contributes to the generation of new olfactory neurons in the adult mouse brain.

GALR3 GALR2

2.32e-046138224726665
Pubmed

USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.

UBA6 UBE2Z

2.32e-046138220975683
Pubmed

Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells.

MKNK1 MAPK3

2.32e-046138215563472
Pubmed

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction.

ULK1 UVRAG

2.32e-046138229313410
Pubmed

Placental alpha(2)-adrenoceptors control vascular development at the interface between mother and embryo.

ADRA2A MAPK3

2.32e-046138212068299
Pubmed

Cyclin C is a haploinsufficient tumour suppressor.

CDK8 MED12

2.32e-046138225344755
Pubmed

Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine.

IL23R DUOXA2

2.32e-046138226261005
Pubmed

Human TopBP1 participates in cyclin E/CDK2 activation and preinitiation complex assembly during G1/S transition.

TOPBP1 CDK2

2.32e-046138217293600
Pubmed

Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6.

UBA6 UBE2Z

2.32e-046138222427669
Pubmed

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

MAP4K1 ULK1 MAPK3 CDK2

2.70e-0478138417192257
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

ADGRG5 GPR82 ADGRB3 ADGRF3

2.83e-0479138412679517
GeneFamilySolute carriers

SLC22A23 SLC35B3 SLC9C2 SLC52A3 SLC30A7 SLC6A6 SLC10A1 SLCO1C1 SLC17A9 SLC35E3 SLC5A12 SLC5A8 SLC39A14 SLC52A2 SLC37A4

8.81e-0939510515752
GeneFamilyGalanin receptors

GALR3 GALR2

9.98e-0531052226
GeneFamilyCyclin dependent kinases

CDK8 CDK19 CDK2

4.49e-04261053496
GeneFamilyCyclins|Mediator complex

CDK8 CDK19 MED12

9.15e-043310531061
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC6

2.50e-03131052807
CoexpressionSINGH_KRAS_DEPENDENCY_SIGNATURE

PRSS22 LAMA3 CLDN7 TMEM45B

3.15e-06201364M2851
CoexpressionGSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_DN

WDR5B SLC22A23 PRSS22 PGGT1B AURKA SCARB2 PAH SLC35E3

9.84e-061991368M6275
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 ALDH1L1 ABCC6 AGMO PAH ASS1 SLC5A12 SLC5A8

1.28e-0718713881b82920588f9e26ef1db244d452736d75fcfd342
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 ALDH1L1 ABCC6 AGMO PAH ASS1 SLC5A12 SLC5A8

1.28e-071871388c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ABCC3 WNT11 POR ABCC6 TLE1 SCARB2 AGMO ASS1

1.57e-071921388e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MFSD6 PRSS22 NDFIP2 CLDN7 ARFGEF3 SLC5A8 TMC5 CPLANE1

1.99e-071981388a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NEK10 ANKUB1 SLC9C2 LRRC9 ADGB ADRA2A TMC5 DUOXA2

2.15e-07200138896701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NEK10 ANKUB1 SLC9C2 LRRC9 ADGB TMC5 SCIN DUOXA2

2.15e-072001388da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NEK10 ANKUB1 SLC9C2 LRRC9 ADGB TMC5 SCIN DUOXA2

2.15e-07200138872c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCelldroplet-Large_Intestine|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGLYRP1 CLDN7 TMEM45B PTPRH SLC5A8 TMC5 SCIN

1.70e-0618313879d7ffcb9804b9a52448ccb56c9370b317a4b52a5
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 ANKUB1 CLDN7 SLC5A8 TMC5 CPLANE1 DUOXA2

2.18e-0619013872fdc024d3d673a0134b74b4c5a63afe924995730
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 PTPRH ASS1 SLC5A8 TMC5 DUOXA2

2.26e-061911387cd709bbcd320373468ea7f058ee5fda8a067b5d0
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRSS22 CLDN7 SLC52A3 TMEM45B RASL11A CERCAM SCIN

2.42e-061931387371f4c98a599923fbe8382530b3eab05d873665a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRSS22 CLDN7 SLC52A3 TMEM45B RASL11A CERCAM SCIN

2.50e-061941387158dc393639e69aecfb014f6106797214ea05fe5
ToppCellNasal_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

PRSS22 CLDN7 SLFN5 ASS1 SLC5A8 TMC5 DUOXA2

2.59e-0619513877509b980b6b293df02bec619ef5b83a6c7b49c03
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 SLFN5 ASS1 SLC5A8 TMC5 DUOXA2

2.59e-0619513873f8ed20ad17afe1545e574e5ca5fe33c3704c7f3
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B PAH ASS1 SLC5A12 SLC39A14 SLC37A4

2.86e-061981387686d973483d027a3ffa2ad4430ba6e50f3d1378e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B PAH ASS1 SLC5A12 SLC39A14 SLC37A4

2.86e-061981387a76366611f3561fc8aca7d62d1f0a0ea2bef7792
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B PTPRH ASS1 SLC5A12 TMC5 SCIN

2.86e-061981387c48b3f026b16d48b8eca9f74dc1e3f3f39a89322
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B PAH ASS1 SLC5A12 SLC39A14 SLC37A4

2.96e-061991387a10768e1cddd2d38291c30d24820a94040a72211
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS22 CLDN7 ARFGEF3 TMEM45B PTPRH SLC5A8 TMC5

2.96e-0619913877223f853335492ca617dbec3e4b6872a8a463a45
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS22 CLDN7 ARFGEF3 TMEM45B PTPRH SLC5A8 TMC5

2.96e-061991387e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B PAH ASS1 SLC5A12 SLC39A14 SLC37A4

2.96e-061991387f26c20f5d7470e90eaa79613d0b87bd4865585a8
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PGLYRP1 SLFN5 ABCC6 SLC52A3 SLCO1C1 S1PR4

7.15e-061491386d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

GALR3 NEK10 GJA4 SCIN IL23R

8.06e-068813851ca0e16981e88030987412e12838a9797b97b9c9
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ACER2 PGLYRP1 SLFN5 SLC52A3 SLCO1C1 S1PR4

8.64e-061541386b0735365de153d4586ca17896431d7bd9c7d8eac
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANKUB1 SLC9C2 LRRC9 ADGB TMC5 DUOXA2

8.96e-0615513865f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANKUB1 SLC9C2 LRRC9 ADGB TMC5 DUOXA2

8.96e-0615513860944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellsevere_influenza-cDC|World / disease group, cell group and cell class (v2)

PGLYRP1 POLE2 GJA4 CD1E ADRA2A NEGR1

1.11e-051611386802f8cafb5f499e3b2ec0193d6eb1ac9320b9287
ToppCell367C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ABCC3 SLC22A23 IGHG2 LIMCH1 SCIN

1.30e-05971385a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell367C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ABCC3 SLC22A23 IGHG2 LIMCH1 SCIN

1.30e-0597138512cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 ASS1 SLC5A8 TMC5 DUOXA2

1.67e-051731386176b956e71d98e8275d698b39437fc326e5fe449
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 ALDH1L1 ABCC6 AGMO SLC5A12 SLC5A8

1.84e-0517613861595dbeee336a81e581325d63208ec6262664ee9
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC3 LAMA3 CLDN7 ADRA2A TMC5 SCIN

2.09e-051801386d1beaf1f106c7efaeaf61f29742d0a7310a83916
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC3 LAMA3 CLDN7 ADRA2A TMC5 SCIN

2.09e-051801386156b988b71f6dcf3117c1e5f4625632cb97e54f2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC6 AGMO PAH ASS1 SLC5A12 SLC5A8

2.16e-0518113869542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC6 AGMO PAH ASS1 SLC5A12 SLC5A8

2.16e-0518113868f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC6 AGMO PAH ASS1 SLC5A12 SLC5A8

2.23e-051821386e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC6 AGMO PAH ASS1 SLC5A12 SLC5A8

2.23e-05182138657bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

PGLYRP1 ABCC6 SLC52A3 SLCO1C1 S1PR4

2.28e-0510913854e4a884b8979f4ff8b232c1581ea78884dda29ed
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ADGRG5 ALDH1L1 ABCC6 ELMO1 PAH SLC39A14

2.44e-0518513861d874608aa2062024323512f68889219471b2f00
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ALDH1L1 ABCC6 AGMO PAH ASS1 SLC5A12

2.52e-0518613868287146f0ba415ea04475588117d4668ae00f75c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 ALDH1L1 ABCC6 AGMO SLC5A12 SLC5A8

2.52e-051861386a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ALDH1L1 ABCC6 AGMO PAH ASS1 SLC5A12

2.59e-05187138671eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ALDH1L1 ABCC6 AGMO PAH ASS1 SLC5A12

2.59e-051871386dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ALDH1L1 ABCC6 AGMO PAH ASS1 SLC5A12

2.59e-051871386f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PRSS22 LAMA3 ABCC6 ADCY7 ARFGEF3 TMC5

2.67e-0518813860d86044bc340e3efb90d0022dd299873639d831c
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 NPTX1 SLC22A23 MAP3K6 ELMO1 SLC5A12

2.75e-05189138609dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACER2 ELOVL5 SLFN5 SLC6A6 GJA4 PRCP

2.84e-0519013866847afca73e1b76c2e86187ccb1a164aefd8f17b
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 ASS1 SLC5A8 TMC5 DUOXA2

2.92e-05191138614851529025cfc2b665f71ebad04150ec543da7a
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 ASS1 SLC5A8 TMC5 DUOXA2

2.92e-051911386529068029fb461df766135576dd0d8b5980f9bc0
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 ASS1 SLC5A8 TMC5 DUOXA2

2.92e-051911386e14b22e882ac92acf8c8b6ee997ef8e799c7a8d5
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SLC22A23 LAMA3 ABCC6 ARFGEF3 LIMCH1 TMC5

3.01e-051921386efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGLYRP1 SLFN5 ABCC6 SLC52A3 SLC6A6 SLCO1C1

3.01e-0519213869ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGLYRP1 SLFN5 ABCC6 SLC52A3 SLC6A6 SLCO1C1

3.01e-051921386a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGLYRP1 SLFN5 ABCC6 SLC52A3 SLC6A6 SLCO1C1

3.01e-05192138666defad13bd8e79319741e43ddb056841710b1d7
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRSS22 CLDN7 PTPRH ASS1 SLC5A8 TMC5

3.10e-05193138671bf8fb5314b79cb30f4eb9c8459b21f10cd6d35
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA8 TH SLCO1C1 NALCN NEGR1 AGMO

3.10e-051931386549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRSS22 CLDN7 PTPRH ASS1 SLC5A8 TMC5

3.10e-051931386b05e110b13d35d34294357c8e1c4fd23bf4b6c92
ToppCellfacs-Trachea-nan-3m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK8 NPTX1 ERO1B CLDN7 SLC5A8 DUOXA2

3.10e-0519313863038ed3e53d3367136fac5c9773cd5b7414f49d3
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDK8 NPTX1 ERO1B CLDN7 SLC5A8 DUOXA2

3.10e-051931386c5925b3b5d19098e3987789d68a493d7fd548ac9
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDK8 NPTX1 ERO1B CLDN7 SLC5A8 DUOXA2

3.10e-0519313866905de261d90dfe3dd2c2cf5b2e26afb2bcc3d5b
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDK8 NPTX1 ERO1B CLDN7 SLC5A8 DUOXA2

3.10e-051931386f73630725f093c646bdaf178c39505c04a16e2c6
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 ARFGEF3 ADRA2A ASS1 TMC5

3.19e-051941386dc531cf9089f2c956621d70d49a2b8219b4b45c1
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACER2 ELOVL5 SLFN5 SLC6A6 GJA4 PRCP

3.19e-0519413862c78e754cac848fd47172f94e392749eb0ab50d4
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACER2 ELOVL5 SLFN5 SLC6A6 GJA4 PRCP

3.19e-05194138692a8e6e3e3f6fd9dacb723b58e7a8b63473e403e
ToppCellEC-Arteriolar_ECs|EC / Lineage and Cell class

CDK19 MFSD6 SLC6A6 GJA4 ASS1 MAPK3

3.28e-051951386fdb855d02ffac53dc0cc38792ce0ae5cb60b85ca
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDK8 NPTX1 ERO1B CLDN7 SLC5A8 DUOXA2

3.28e-0519513864d7ca21f14730e1b6d0473bc1a11aa626db948f3
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell-epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDK8 NPTX1 ERO1B CLDN7 SLC5A8 DUOXA2

3.28e-0519513868727554ef047ca7f1d4b888a8468f148c64a6918
ToppCelldroplet-Trachea-nan-3m-Epithelial-epithelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK8 NPTX1 ERO1B CLDN7 SLC5A8 DUOXA2

3.28e-0519513869f0ee826d4f0997aee8d63284ed24549bbdf6a28
ToppCellSecretory|World / shred by cell class for bronchial biopsy

CLDN7 SLC30A7 ARFGEF3 SLC5A8 TMC5 DUOXA2

3.28e-05195138652f8281fe0df67cec3faa780a23ed6343ed5a6ba
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CLDN7 ARFGEF3 ADRA2A ASS1 SLC5A8 TMC5

3.38e-051961386057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 ANKUB1 SLC9C2 LRRC9 ADGB CPLANE1

3.47e-05197138674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellmLN-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

LAMA3 NDFIP2 YIPF2 IGHG2 ASS1 CERCAM

3.47e-051971386bd1d01d6c49f68f5c85d84df96c90dd04b9de09b
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CLDN7 ARFGEF3 ADRA2A ASS1 SLC5A8 TMC5

3.47e-0519713863f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 PTPRH ASS1 TMC5 DUOXA2

3.47e-051971386adb4e27d73ae2e6a39d212c0ead3ac0ad62d9131
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 TMC5 SCIN

3.57e-051981386e3e2233c796d5e9051c8c1b66f70f406f048ed56
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 SLC39A14 SLC37A4

3.57e-051981386ecdef1a0a0b8399e193b922c8ca8c25e63de4a4f
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 TMC5 SCIN

3.57e-0519813868fac96132663f54566136ef54b53684d31dfde32
ToppCell3'-Child09-12-SmallIntestine-Epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 TMC5 SCIN

3.67e-051991386043c65bdf54a1bf0e483fea9ffc042ff5b271764
ToppCellsevere-Myeloid-Neutrophils_4|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PGLYRP1 CYBC1 POR MKNK1 SLC6A6 S1PR4

3.67e-05199138650242666def13e5d4149c563ae000d6768f086f7
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ELFN2 ABCA8 TH SLCO1C1 NEGR1 AGMO

3.67e-0519913863835452e4848d7f7dd8651c17b746b271ef39688
ToppCell3'-Child04-06-SmallIntestine-Epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 TMC5 SCIN

3.67e-051991386ab71b312635a2b2c98d71b60a299f44bc80a3587
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP26A1 CLDN7 ASS1 SLC5A8 TMC5 SCIN

3.67e-0519913861e693d7bb481bf03a943b460a69787229625d7b1
ToppCelltumor_Lung-Epithelial_cells-tS2|tumor_Lung / Location, Cell class and cell subclass

ABCC3 PRSS22 CLDN7 TMEM45B ASS1 TMC5

3.67e-05199138628ec59e01061287fb0892491790b316e2b93e232
ToppCelltumor_Lung-Epithelial_cells|tumor_Lung / Location, Cell class and cell subclass

ABCC3 PRSS22 CLDN7 ARFGEF3 ASS1 TMC5

3.67e-05199138656b3f6c8b561d60780d91daf6b44a9dcf616e599
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 TMC5 SCIN

3.67e-0519913860181c13379f869be47804cdb11bbdabcd30b9b23
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 SLC39A14 SLC37A4

3.67e-051991386914f66e2b4af323d09fa2340a39cf8051d00a422
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 TMC5 SCIN

3.67e-051991386ee981046217e8759610eb58a670d98f32cd83abc
ToppCellcontrol-Epithelial|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRSS22 POR NDFIP2 CLDN7 ARFGEF3 TMC5

3.78e-052001386f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS22 POR NDFIP2 CLDN7 ARFGEF3 TMC5

3.78e-052001386d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CLDN7 ARFGEF3 ADRA2A SLC17A9 SLC5A8 TMC5

3.78e-052001386292c63693eb7f435335a8cfba07aa35b72139393
ToppCellNasal_Brush-Epithelial|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

PRSS22 POR CLDN7 ASS1 SLC5A8 TMC5

3.78e-0520013867911073119ee47a37b68b73fc54f063e902a5067
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 SLC39A14 SLC37A4

3.78e-0520013863e13c9a4ba99a7dfbf738b0fb63fb54b4dee5897
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS22 CLDN7 ASS1 SLC5A8 TMC5 DUOXA2

3.78e-052001386b68d212159b9d04866ba02ff55c35be247805eec
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLDN7 TMEM45B ASS1 SLC5A12 SLC39A14 SLC37A4

3.78e-05200138673bfdf068a8ecbefc1e6afe9686df73658ee042f
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PGLYRP1 SLFN5 ABCC6 SLC52A3 S1PR4

5.51e-051311385308ddb7fe113eac5dbeb9cb0b688d9e09275ce5e
ToppCellCOVID_vent-Lymphocytic-T_cell-Gamma_Delta_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

GPR82 LRRC9 TSPAN16 PTPRH IL23R

5.71e-051321385dbc0a332fd8f63ebdcf9716e45d7f46f26509349
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TMPRSS9 NPTX1 PTPRH METTL18 ASS1

5.92e-051331385386c9bbd9bab62209a67ebae6cd6ac0d7cef0a2d
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADGRG5 PRSS22 LAMA3 PTPRH

6.64e-057013848d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

PGLYRP1 SLFN5 ABCC6 SLC52A3 S1PR4

7.30e-05139138534398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

PGLYRP1 SLFN5 ABCC6 SLC52A3 S1PR4

7.30e-051391385450c4152c9fe4ec503271bb3cf93739918c59509
Diseaseecosanoids measurement

ABCC3 TTC27 POR SLCO1C1 VDAC2

5.19e-06551345EFO_0020044
DiseaseBrown-Vialetto-Van Laere Syndrome 1

SLC52A3 SLC52A2

2.05e-0521342C0796274
Diseasedevelopmental and epileptic encephalopathy 87 (implicated_via_orthology)

CDK8 CDK19

2.05e-0521342DOID:0112221 (implicated_via_orthology)
DiseaseDepressive disorder

GALR2 ADCY7 TH ADRA2A SLCO1C1 TLE1 MAPK3 MED12

5.52e-052891348C0011581
DiseaseBrown-Vialetto-Van Laere syndrome (implicated_via_orthology)

SLC52A3 SLC52A2

6.12e-0531342DOID:0050694 (implicated_via_orthology)
DiseaseNADPH--cytochrome P450 reductase measurement

POR VDAC2

1.22e-0441342EFO_0008242
DiseaseMental Depression

ADCY7 TH ADRA2A SLCO1C1 TLE1 MAPK3 MED12

1.67e-042541347C0011570
DiseaseGrey matter density measurement

PGLYRP1 WNT11 UVRAG

4.94e-04341343EFO_0010306
Diseaseblood barium measurement

NEGR1 SLC5A12 SLC5A8

4.94e-04341343EFO_0021528
DiseaseDisorder of amino acid metabolism

PAH ASS1

5.63e-0481342cv:C0002514
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

POR VDAC2

7.22e-0491342EFO_0600040
Diseasehyperprolactinemia (biomarker_via_orthology)

ABCC3 TH

7.22e-0491342DOID:12700 (biomarker_via_orthology)
Diseasecoffee consumption measurement, tea consumption measurement

CYP26A1 POR VDAC2

1.06e-03441343EFO_0006781, EFO_0010091
Diseasetriacylglycerol 56:2 measurement

LIMCH1 SLC5A12

1.10e-03111342EFO_0010429
Diseaseheat shock protein beta-1 measurement

POR VDAC2

1.31e-03121342EFO_0010595
Diseasecholestasis (biomarker_via_orthology)

ABCC3 ALDH1L1 SLC10A1

1.45e-03491343DOID:13580 (biomarker_via_orthology)
Diseasegastric ulcer (implicated_via_orthology)

MAPK3 HRH3

1.80e-03141342DOID:10808 (implicated_via_orthology)
DiseaseMetastatic melanoma

NEK10 AURKA MAP4K1

1.92e-03541343C0278883
DiseaseGeneralized hypotonia

CDK8 AGO1

2.07e-03151342C1858120
Diseasecoffee consumption, cups of coffee per day measurement

POR VDAC2

2.36e-03161342EFO_0004330, EFO_0006782
Diseaseulcerative colitis, Crohn's disease

ADCY7 IL23R

3.69e-03201342EFO_0000384, EFO_0000729
Diseasecortisol measurement

TMPRSS9 MKNK1

3.69e-03201342EFO_0005843
Diseasecerebellum white matter volume change measurement, age at assessment

ADGRB3 ABCA8

3.69e-03201342EFO_0008007, EFO_0021498
DiseaseCCL24 measurement

POR VDAC2

4.46e-03221342EFO_0009418

Protein segments in the cluster

PeptideGeneStartEntry
ECWLDGKGGALYTFV

ADGRF3

916

Q8IZF5
EYCIWTDGLNALLGK

ELMO1

661

Q92556
YTKAIDIWAIGCIFA

CDK19

211

Q9BWU1
DLWSLGVLCYEFLVG

AURKA

311

O14965
EKWAFIGVPYVSLLC

ACER2

251

Q5QJU3
VCFSALVRWGEYGAL

ADGB

686

Q8N7X0
QDFWCSTLVKGVIYG

ADGRB3

26

O60242
YAGVLIIWDKIFGTF

AGMO

236

Q6ZNB7
SCDIWGTKEVDYLGL

CREBRF

106

Q8IUR6
SFYTWLEGLCLEKRV

ERO1B

231

Q86YB8
YNGIEIKVWAIACFA

AGO1

441

Q9UL18
GLYTEACFVLAEGWF

POLE2

216

P56282
WACLVALGYVLVFDA

ADCY7

101

P51828
YSGGLDTSCILVWLK

ASS1

11

P00966
LSVFWDYAKAVGLCT

ABCC3

956

O15438
GKTCAICGQYFITVW

LRRC69

286

Q6ZNQ3
FCAWDFRTYGITGVK

LRRC9

416

Q6ZRR7
IYGGATKWTFEACRQ

NPTX1

416

Q15818
FARKLCIYIWGVVLG

GPR82

151

Q96P67
WVACIKAEGVLLDYL

LAMA3

846

Q16787
LWKLIEGGAHIYVCG

POR

616

P16435
GITGSADVLFSCWYL

NEGR1

321

Q7Z3B1
CELVTGVWEGKYNFF

ELOVL5

81

Q9NYP7
GKALDVWATGVTLYC

CAMKK1

331

Q8N5S9
VWATGVTLYCFVYGK

CAMKK1

336

Q8N5S9
VYSWKEGACADIALV

PRSS22

131

Q9GZN4
YGKAADIWSLGCTVI

MAP3K6

826

O95382
WGCLGYTLVREFSKD

NAT14

191

Q8WUY8
LGKSIDWGILAVFTC

PDCD2

306

Q16342
YGEKADVWAVGCILY

NEK10

706

Q6ZWH5
WLGYSLISFDGCLTQ

OR52B6

106

Q8NGF0
KTLGWCDVGYNFLIG

PGLYRP1

86

O75594
ILFYTGNEGDIIWFC

PRCP

86

P42785
LTGYCKSLSAEWLGV

MED12

1081

Q93074
VYEGGLKIWECTFDL

METTL18

161

O95568
GYTKSIDIWSVGCIL

MAPK3

221

P27361
GCITQLYVFLWLGAT

OR2C1

96

O95371
AATLWTYGLYFCGKI

OR5M3

156

Q8NGP4
WDLIKLLCSVQYGSV

MFSD6

436

Q6ZSS7
ILFWYICSGSVKLPE

DSTYK

836

Q6XUX3
LATIYWFTVEFGLCK

PAH

321

P00439
GFKGLFYLHSLIWTC

OOSP1

6

A8MZH6
EGLLLIAIFWCYEKF

SLC10A1

296

Q14973
RYGAICGFGLSLIKW

NDFIP2

261

Q9NV92
YTLDGWVFGSLLCKA

GALR2

86

O43603
TIYTLDAWLFGALVC

GALR3

81

O60755
LWVLSTGYLVVFGVK

SLC37A4

226

O43826
YGAAFWVTLATGVLC

DUOXA2

246

Q1HG44
WGGYSIFLILICLTV

CD1E

301

P15812
VLCEGVKWLSFHSGY

CNOT7

146

Q9UIV1
ECFLLGSYEKSVQLW

CPLANE1

836

Q9H799
WLLYIIHGFCGQSKL

FIG4

246

Q92562
ACGSGYVISKDIVKW

B3GALNT2

411

Q8NCR0
AGVAFARYILVGCWK

ARFGEF3

856

Q5TH69
VIALYILFSWCHGGI

IL23R

11

Q5VWK5
SGDSLGWKLFYVTGC

CYBC1

41

Q9BQA9
GWKLFYVTGCLFVAV

CYBC1

46

Q9BQA9
CLGGALYWKELAVLA

AS3MT

206

Q9HBK9
TFGRGLCKLWLVVDY

HRH3

101

Q9Y5N1
FLAAIKLWDLYCVSG

CYP26A1

21

O43174
CLVKGFYPSDISVEW

IGHG2

246

P01859
CKSVLEAGFLYGQWR

GJA4

161

P35212
TARCWTYLTGVILGK

HDAC8

311

Q9BY41
GCKYYSTAVDIWSLG

CDK2

176

P24941
KGEVGCFLSHYSIWE

CERCAM

386

Q5T4B2
GKYIVCSSALGLYQW

FBXW2

336

Q9UKT8
YTKAIDIWAIGCIFA

CDK8

211

P49336
WQVSILFLGTYICSG

PRSS46P

56

E5RG02
ATKTSRVYGFIGLCW

S1PR4

156

O95977
VEVWGYGLLCVTVIS

SLC39A14

151

Q15043
ACYWLKGVRYSDIGT

SLC39A14

321

Q15043
VLVTIYWLGKAANSC

LIMCH1

126

Q9UPQ0
VTYKTGCTLWGIFFI

MS4A13

31

Q5J8X5
KLCALLVAGSYTWGI

OR5D13

141

Q8NGL4
TFYDKRCDLWSLGVV

MKNK1

276

Q9BUB5
VALKGGYNELCDIWS

MAP4K1

186

Q92918
CYSFWVGATLKLLKI

PGGT1B

271

P53609
DVFEKICWGLGIEYT

MRPS15

176

P82914
KCVQWAEGFLLVYSI

RASL11A

101

Q6T310
AKTLGIAVGIYLLCW

TAAR5

251

O14804
SCFVVKIWGGKENIY

UVRAG

111

Q9P2Y5
RTICVGDIVWAKIYG

PWWP2A

651

Q96N64
TCWEKICPLFSGIGY

SLC6A6

111

P31641
ASWVLFSGCLSYVKV

SLC52A3

401

Q9NQ40
LYKDGGVAIIDQWIC

POFUT2

361

Q9Y2G5
QSSGVLFGYWLLCFV

ABCC6

131

O95255
FIIDLGTEIYQWCGS

SCIN

166

Q9Y6U3
KDDSCGTIGSFLLWY

SSMEM1

31

Q8WWF3
IFGYLITGCIADWVG

SLC22A23

241

A1A5C7
EGYCILGEKTSWYEV

PKDREJ

1116

Q9NTG1
WIGGDLTNFKGCYLT

SLC66A1L

51

A1A4F0
VLSWVLCLGVFSYVK

SLC52A2

376

Q9HAB3
CWIVISSYFDEKGLV

POLR2B

26

P30876
TQFLVCYRLKEASGW

SHKBP1

211

Q8TBC3
TGFGCATIFWLLKYR

SHPK

151

Q9UHJ6
LIFSVEGFKSCGWYL

SLC35B3

101

Q9H1N7
EGFKSCGWYLTLVQF

SLC35B3

106

Q9H1N7
YCTLGGLKAVIWTDV

SLC5A8

176

Q8N695
GVFFGLVFTWLACKG

SCARB2

446

Q14108
EAGIVLSSFFWGYCL

SLC17A9

61

Q9BYT1
IGYKIWCGTTTQGYL

PGBD1

566

Q96JS3
YCEVSVFWKEGFVAL

ABCA8

166

O94911
LLTVFWGCLGFTSLY

ABCA8

336

O94911
FGKAWCEIYLALDVL

ADRA2A

116

P08913
SLEGYTLTCVFWKEG

ADGRG5

181

Q8IZF4
RYFAGWCDKIQGSTI

ALDH1L1

531

O75891
FCGYIELTEWALKQG

ANKUB1

201

A6NFN9
FIVAGLAALVACSWY

CLDN7

126

O95471
KDSFLWRYGKVGCIS

PRY

56

O14603
GSFFLIIGLCWSVKY

TMEM45B

11

Q96B21
WYGATKESRGTLLFC

TSPAN16

76

Q9UKR8
VTGKFSPLCQWLYLE

UBA6

406

A0AVT1
DVWSVGVIFFQCLYG

TLK1

656

Q9UKI8
WLGVFLDYECGIVSF

TRIM77

406

I1YAP6
VLSLKFAYCGKWFVS

TLE1

701

Q04724
YCIFANFSVTGGKWI

WDR5B

256

Q86VZ2
CSLDGTIKLWDYIDG

WDR75

76

Q8IWA0
IYKKAVGWTCDFVGS

WDR75

481

Q8IWA0
LFKALGWAAVYLSTC

TAPBP

426

O15533
VYFGVLIDTSCLKWG

SLCO1C1

606

Q9NYB5
CLISGWGYLKEDFLV

TMPRSS9

326

Q7Z410
TGTLETKYKWCEYGL

VDAC2

66

P45880
VLCRWTDGLYYLGKI

PHF19

46

Q5T6S3
SWVSLYCVLSKGELG

SPTBN4

2441

Q9H254
YGILSLVVSEKYIWC

TECPR2

811

O15040
GWSYLVFCLKDDVVL

TBC1D15

146

Q8TC07
GSYVFWCLLLISKAG

GTF3C4

396

Q9UKN8
FYRNGKVCLSILGTW

UBE2Z

181

Q9H832
FWTLCSDVYVGTLKL

SLC30A7

326

Q8NEW0
KAWIGACEVYILLTS

ZUP1

421

Q96AP4
ALQTGVCYGIKWLAL

WNT11

16

O96014
LGSIIFGYWCAKIIQ

SLC9C2

226

Q5TAH2
YSGGITKLIFCWDFT

TMC5

561

Q6UXY8
KVTVAGISIYCYAWL

YIPF2

161

Q9BWQ6
FYCTLGGLKAVVWTD

SLC5A12

171

Q1EHB4
LGVWFSLGCAYLALE

TTC27

561

Q6P3X3
CLAGTWALGVGAKYT

TMEM177

176

Q53S58
LEPGCLYVFSVWVGK

PTPRH

356

Q9HD43
VVGAKWLLECFSKGY

TOPBP1

421

Q92547
FVVTWLGLYICQKLD

SLC35E3

51

Q7Z769
ILYTIFSKWDAGCKG

SLFN5

451

Q08AF3
KADLWSIGTIVYQCL

ULK1

201

O75385
LIEGDKGYVWLAICS

ELFN2

26

Q5R3F8
KLSTLYWFTVEFGLC

TH

396

P07101
LEALLKIWCLGFTGY

NALCN

431

Q8IZF0
KIWCLGFTGYISSSL

NALCN

436

Q8IZF0