Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type endopeptidase activity

HGFAC HABP2 KLK6 HPN PROC

8.69e-06190305GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

HGFAC HABP2 KLK6 HPN PROC

1.32e-05207305GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

HGFAC HABP2 KLK6 HPN PROC

1.48e-05212305GO:0017171
GeneOntologyMolecularFunctionendopeptidase activity

HGFAC HABP2 KLK6 HPN PROC

4.13e-04430305GO:0004175
GeneOntologyMolecularFunctioncyclin binding

HERC6 FBXW7

1.26e-0335302GO:0030332
GeneOntologyMolecularFunctionubiquitin protein ligase activity

XIAP NEURL2 HERC6 FBXW7

2.21e-03372304GO:0061630
GeneOntologyMolecularFunctionpeptidase activity

HGFAC HABP2 KLK6 HPN PROC

2.68e-03654305GO:0008233
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

XIAP NEURL2 HERC6 FBXW7

2.83e-03398304GO:0061659
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

XIAP NEURL2 HERC6 FBXW7

5.23e-03473304GO:0004842
GeneOntologyBiologicalProcessprotein maturation

ENGASE HGFAC XIAP KLK6 HPN TBCD SPCS2

1.86e-05619297GO:0051604
GeneOntologyBiologicalProcessprotein processing

HGFAC XIAP KLK6 HPN SPCS2

4.40e-05285295GO:0016485
GeneOntologyCellularComponentjunctional membrane complex

JPH1 JPH2

6.65e-059292GO:0030314
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

JPH1 JPH2

8.30e-0510292GO:0014701
DomainTRYPSIN_SER

HGFAC HABP2 KLK6 HPN PROC

3.01e-0790305IPR033116
DomainTRYPSIN_HIS

HGFAC HABP2 KLK6 HPN PROC

5.91e-07103305IPR018114
DomainTRYPSIN_SER

HGFAC HABP2 KLK6 HPN PROC

6.82e-07106305PS00135
DomainTRYPSIN_HIS

HGFAC HABP2 KLK6 HPN PROC

7.14e-07107305PS00134
DomainPeptidase_S1A

HGFAC HABP2 KLK6 HPN PROC

9.37e-07113305IPR001314
DomainTRYPSIN_DOM

HGFAC HABP2 KLK6 HPN PROC

1.02e-06115305PS50240
DomainTryp_SPc

HGFAC HABP2 KLK6 HPN PROC

1.11e-06117305SM00020
DomainTrypsin

HGFAC HABP2 KLK6 HPN PROC

1.31e-06121305PF00089
DomainTrypsin_dom

HGFAC HABP2 KLK6 HPN PROC

1.31e-06121305IPR001254
DomainPeptidase_S1_PA

HGFAC HABP2 KLK6 HPN PROC

1.43e-06123305IPR009003
DomainJunctophilin

JPH1 JPH2

1.49e-054302IPR017191
DomainKringle-like

HGFAC PLA2R1 HABP2

1.80e-0532303IPR013806
DomainEGF

HGFAC HABP2 SVEP1 PROC

4.72e-05126304PF00008
Domain-

HGFAC PLA2R1

1.92e-04133022.10.10.10
DomainMORN

JPH1 JPH2

2.24e-0414302SM00698
DomainFN_type2_col-bd

HGFAC PLA2R1

2.24e-0414302IPR000562
DomainFN2_2

HGFAC PLA2R1

2.24e-0414302PS51092
Domainfn2

HGFAC PLA2R1

2.24e-0414302PF00040
DomainFN2_1

HGFAC PLA2R1

2.24e-0414302PS00023
DomainFN2

HGFAC PLA2R1

2.24e-0414302SM00059
DomainMORN

JPH1 JPH2

2.59e-0415302PF02493
DomainMORN

JPH1 JPH2

2.59e-0415302IPR003409
DomainKringle

HGFAC HABP2

3.34e-0417302IPR000001
DomainKringle

HGFAC HABP2

3.34e-0417302PF00051
DomainKRINGLE_1

HGFAC HABP2

3.34e-0417302PS00021
DomainKringle_CS

HGFAC HABP2

3.34e-0417302IPR018056
DomainKR

HGFAC HABP2

3.34e-0417302SM00130
DomainKRINGLE_2

HGFAC HABP2

3.34e-0417302PS50070
DomainEGF_3

HGFAC HABP2 SVEP1 PROC

5.18e-04235304PS50026
DomainEGF

HGFAC HABP2 SVEP1 PROC

5.18e-04235304SM00181
DomainEGF-like_dom

HGFAC HABP2 SVEP1 PROC

6.43e-04249304IPR000742
DomainEGF_1

HGFAC HABP2 SVEP1 PROC

7.03e-04255304PS00022
DomainEGF-like_CS

HGFAC HABP2 SVEP1 PROC

7.67e-04261304IPR013032
DomainEGF_2

HGFAC HABP2 SVEP1 PROC

8.12e-04265304PS01186
DomainEGF_CA

HABP2 SVEP1 PROC

9.71e-04122303SM00179
DomainEGF-like_Ca-bd_dom

HABP2 SVEP1 PROC

1.02e-03124303IPR001881
DomainSushi

CSMD1 SVEP1

3.15e-0352302PF00084
DomainCCP

CSMD1 SVEP1

3.39e-0354302SM00032
DomainSUSHI

CSMD1 SVEP1

3.64e-0356302PS50923
DomainSushi_SCR_CCP_dom

CSMD1 SVEP1

3.77e-0357302IPR000436
DomainEGF_Ca-bd_CS

SVEP1 PROC

1.06e-0297302IPR018097
DomainEGF_CA

SVEP1 PROC

1.10e-0299302PS01187
DomainASX_HYDROXYL

SVEP1 PROC

1.12e-02100302PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SVEP1 PROC

1.25e-02106302IPR000152
PathwayREACTOME_MET_RECEPTOR_ACTIVATION

HGFAC HPN

3.47e-056222MM15346
PathwayREACTOME_MET_RECEPTOR_ACTIVATION

HGFAC HPN

3.47e-056222M27644
Pubmed

A versatile single-plasmid system for tissue-specific and inducible control of gene expression in transgenic mice.

JPH1 JPH2

7.19e-07230221518849
Pubmed

Deficiency of triad junction and contraction in mutant skeletal muscle lacking junctophilin type 1.

JPH1 JPH2

7.19e-07230211535622
Pubmed

Junctophilin damage contributes to early strength deficits and EC coupling failure after eccentric contractions.

JPH1 JPH2

7.19e-07230219940065
Pubmed

Deficiency of triad formation in developing skeletal muscle cells lacking junctophilin type 1.

JPH1 JPH2

7.19e-07230212135771
Pubmed

Characterization of human junctophilin subtype genes.

JPH1 JPH2

2.16e-06330210891348
Pubmed

Junctophilin 1 and 2 proteins interact with the L-type Ca2+ channel dihydropyridine receptors (DHPRs) in skeletal muscle.

JPH1 JPH2

2.16e-06330222020936
Pubmed

Junctophilins: a novel family of junctional membrane complex proteins.

JPH1 JPH2

2.16e-06330210949023
Pubmed

Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle.

JPH1 JPH2

2.16e-06330223148318
Pubmed

Physical interaction of junctophilin and the CaV1.1 C terminus is crucial for skeletal muscle contraction.

JPH1 JPH2

2.16e-06330229632175
Pubmed

Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence.

JPH1 JPH2

2.16e-06330235089322
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

PLA2R1 HABP2 KLK6 ACVR2B CSMD1 ARSL MED13 SPCS2

1.01e-05129330815342556
Pubmed

Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth.

HGFAC HPN

2.01e-05830217174946
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

JPH1 JPH2

4.72e-051230219095005
Pubmed

Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.

JPH1 JPH2

4.72e-051230223715556
Pubmed

FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.

MED13 FBXW7

7.50e-051530231285543
Pubmed

Functional analysis of candidate genes from genome-wide association studies of hearing.

FZD6 CSMD1

9.70e-051730231927188
Pubmed

Genetic determinants of P wave duration and PR segment.

ACVR2B MED13

9.70e-051730224850809
Pubmed

The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator.

MED13 FBXW7

3.29e-043130223322298
Pubmed

Genome-wide association study of lung function decline in adults with and without asthma.

CSMD1 SVEP1

3.51e-043230222424883
Pubmed

The human plasma proteome: a nonredundant list developed by combination of four separate sources.

HGFAC HABP2 PROC

3.87e-0416530314718574
Pubmed

A new intracellular targeting motif in the cytoplasmic tail of the spike protein may act as a target to inhibit SARS-CoV-2 assembly.

XIAP SPCS2

3.97e-043430236572190
Pubmed

DNA Damage Regulates Translation through β-TRCP Targeting of CReP.

MED13 FBXW7

4.20e-043530226091241
Pubmed

DNA sequence and analysis of human chromosome 8.

JPH1 CSMD1

7.92e-044830216421571
InteractionF7 interactions

HABP2 HPN PROC

5.90e-0624303int:F7
Cytoband20q13.12

JPH2 NEURL2

7.14e-046030220q13.12
Cytoband17q25.3

ENGASE TBCD

2.00e-0310130217q25.3
CytobandEnsembl 112 genes in cytogenetic band chr4p16

HGFAC SPON2

9.26e-03222302chr4p16
CytobandEnsembl 112 genes in cytogenetic band chr8p23

CSMD1 RP1L1

1.02e-02234302chr8p23
CytobandEnsembl 112 genes in cytogenetic band chr17q25

ENGASE TBCD

1.71e-02307302chr17q25
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD1 SVEP1

1.29e-03571721179
GeneFamilyProteases, serine

KLK6 HPN

1.57e-0363172738
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC HABP2 SPON2 PROC

6.54e-06182304770ce9f3f4538d0181a0181543841bc964c68274
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC HABP2 SPON2 PROC

6.54e-0618230477ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC HABP2 SPON2 PROC

6.54e-061823044921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC HABP2 HPN PROC

6.68e-06183304d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HABP2 ARSL HPN PROC

9.12e-061983041c598e1351556f61da7b50961dd55f84a317c068
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HABP2 ARSL HPN PROC

9.12e-061983040617e015601a3acecf22844c01053671a97cfadb
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HABP2 ARSL HPN PROC

9.12e-061983040d9bb0530af6af1d9f64baa2f1e77ffc7f0e5233
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)|Cerebellum / BrainAtlas - Mouse McCarroll V32

PLA2R1 SPON2 C8orf58

9.89e-051343031fa13185a4dfb4563473184c0c4f449011d88631
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

PLA2R1 SPON2 C8orf58

9.89e-051343031ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Cerebellum / BrainAtlas - Mouse McCarroll V32

PLA2R1 SPON2 C8orf58

9.89e-051343038a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCellTCGA-Bile_Duct|World / Sample_Type by Project: Shred V9

HGFAC HABP2 PROC

1.13e-04140303ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HABP2 CSMD1 FLG2

1.20e-041433036df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 LACC1 SVEP1

1.22e-04144303cf9f049ab6cd80521598124f057c2debdde24788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 LACC1 SVEP1

1.22e-0414430341eaeca54b3c39de417597267cbdb1f195dd885a
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

JPH1 LACC1 C8orf58

1.27e-04146303bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HABP2 KLK6 CSMD1

1.35e-0414930324a7538b54b2a5291503c7493fefed4e45e8d710
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HABP2 KLK6 CSMD1

1.35e-04149303cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FZD6 PLA2R1 SPON2

1.52e-04155303d8b5145258f075b15080f8739f537f48dd22225e
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FZD6 PLA2R1 SPON2

1.52e-04155303ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FZD6 PLA2R1 SPON2

1.52e-041553030f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DENND5B SPCS2 FBXW7

1.58e-0415730363502d0fd5972d71cdbe13bde167592c70acec32
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|356C / Donor, Lineage, Cell class and subclass (all cells)

ITPRIPL2 NEURL2 PROC

1.83e-0416530335a6de30438de364ccca948fc932da541a69ef89
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND5B SPCS2 FBXW7

1.89e-041673030130743084dbcb20e10f96715d30961122150cbf
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HABP2 SPON2 SVEP1

1.89e-041673033e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HABP2 SPON2 SVEP1

1.89e-041673033ad9f3122dbe96580f640388ef920ea209fc2349
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND5B SPCS2 FBXW7

1.89e-041673037bcae3797d3a0811e7f39885afdfd29ec517f11b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND5B SPCS2 FBXW7

1.89e-04167303c6f0209a1ad797631fdfa3efab6db6b1d3e8e315
ToppCellfacs-Kidney|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HABP2 HPN PROC

1.93e-04168303d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JPH2 HABP2 PROC

1.96e-04169303daed9083ee05c220365200328c2c50047fe21efd
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

FZD6 ITPRIPL2 RP1L1

2.03e-04171303adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

JPH2 SPON2 SVEP1

2.10e-0417330388be9182fbb1bc83531cd41e59ea57c112a21d54
ToppCellPlasma_cells|World / lung cells shred on cell class, cell subclass, sample id

DENND5B SPCS2 FBXW7

2.10e-0417330352a387e2a4694af61a9223a4c2ecf4e6f762c064
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B NEURL2 FBXW7

2.10e-041733038bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B NEURL2 FBXW7

2.10e-041733033e3c61468e703330788a10d850ef41a85680f86d
ToppCellControl-B_cells-Plasma_cells|Control / group, cell type (main and fine annotations)

DENND5B SPCS2 FBXW7

2.17e-04175303fb23858cfce71509cafbe0d9728e678012ff2962
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HABP2 ARSL HPN

2.25e-041773032af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC LACC1 SVEP1

2.29e-04178303e86ed30652c2de70f16430f04b78789b87df4af2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC LACC1 SVEP1

2.32e-041793030b6731d9554f8bed1899c165a50e6b329ea19a6d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC LACC1 SVEP1

2.40e-0418130303a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SPON2 HPN

2.40e-0418130375340f0c06977c88f9d2e56265f4aa84d706d2c6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC LACC1 SVEP1

2.44e-0418230386a2330ada7637144a67afbf9f3a902901ab1130
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FZD6 HGFAC HABP2

2.44e-04182303d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CSMD1 HPN PROC

2.48e-0418330385446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

DENND5B SPCS2 FBXW7

2.48e-04183303130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

DENND5B SPCS2 FBXW7

2.48e-041833032c016bb59f131a0e821853b085289a3583f0a729
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|lung / Disease (COVID-19 only), tissue and cell type

DENND5B SPCS2 FBXW7

2.52e-04184303480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HABP2 ARSL HPN

2.56e-04185303d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCellfacs-Heart-LV-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC HPN PROC

2.56e-04185303a835f821a5e6568d648df831ec4c2d0048d67093
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC LACC1 SVEP1

2.56e-0418530379cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCellfacs-Heart-LV-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC HPN PROC

2.56e-04185303386b08bcb304db543e3c5ff75f85e99bf0c592df
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SPON2 HPN

2.56e-04185303e29079ef09aee62c3e9756341db4e59ca9dbf7ac
ToppCellfacs-Large_Intestine-Distal-24m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SPON2 HPN

2.56e-041853032ecc4b76b3645b65c226c2298bff307cc6479172
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

ENGASE CSMD1 SVEP1

2.60e-04186303e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

DENND5B SPCS2 FBXW7

2.60e-0418630366676d9395172de5707e204826a1c9f73b448cca
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC LACC1 SVEP1

2.64e-04187303d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

DENND5B SPCS2 FBXW7

2.68e-04188303c7b1807c96f87fbcd37739a159cf00f9a1ff5d71
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|COVID-19 / Disease (COVID-19 only), tissue and cell type

DENND5B SPCS2 FBXW7

2.68e-04188303599195338070ac6b79bd114609d9e10cac4f1df4
ToppCellcellseq2-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND5B SPCS2 FBXW7

2.68e-0418830333360f1c30315d9772731c9067834dc059172b79
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC LACC1 SVEP1

2.68e-04188303ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DENND5B SPCS2 FBXW7

2.68e-04188303567b08514d9d84cbb40f9b7a679eec304f023428
ToppCellB_cells-Plasmablasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

DENND5B SPCS2 FBXW7

2.72e-0418930387cb7b6ba9fd57100d68e6eaeecd1ac6ab22d1c6
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 SPON2 SVEP1

2.77e-0419030300fd993675faf53adf985b9316a18c8a33242029
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 SPON2 SVEP1

2.77e-041903038cda09d761c6b504a744959d587c183f94f1beeb
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-041913035c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-0419130336467322096bc766cd777dae3bfb4e65511e492c
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-04191303d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLA2R1 ARSL HPN

2.81e-04191303a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B SPON2 PROC

2.81e-041913033e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B SPON2 PROC

2.81e-04191303bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B SPON2 PROC

2.81e-04191303989bf108c7f2c78dd7f14481570f1819673a5469
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-041913038a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-04191303de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCellCOVID-19-Lymphoid-pDC|COVID-19 / Condition, Lineage and Cell class

DENND5B SPON2 PROC

2.81e-0419130325343b11d42128ad16659e5519cd1673266cc505
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-0419130394795daf05061baa3b72a1b01c9e940af86de044
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-04191303b5210de890d338602857b5907135705a507bc2b0
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-04191303cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-04191303c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-0419130380484d39f34703a33b9bac09826b7a526e883cab
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-04191303243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCelldroplet-Lung-21m-Mesenchymal|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-0419130310a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.81e-04191303d4f535b06ad483448ab692e9900c872c78cbed60
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DENND5B SPON2 PROC

2.85e-04192303d9ff2293358c8b031ba212021012e058014ff472
ToppCelldroplet-Lung-30m-Mesenchymal|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 SPON2 SVEP1

2.85e-041923035d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD1 SPON2 SVEP1

2.85e-04192303853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCellHippocampus-Endothelial|Hippocampus / BrainAtlas - Mouse McCarroll V32

FZD6 PLA2R1 ITPRIPL2

2.85e-0419230336deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCellSevere_COVID-19-Myeloid-pDC|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DENND5B SPON2 PROC

2.85e-04192303f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DENND5B SPON2 PROC

2.85e-041923032e8611d65090e39f1a6e74c972288e7b68376d15
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FZD6 ARSL HPN

2.85e-0419230339804d9ddc67c1b41887752df2503389eae44a1a
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD1 SPON2 SVEP1

2.85e-0419230349281626ecad0456fdbded2378b7028d7b589686
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DENND5B SPON2 PROC

2.85e-0419230343569726df281eebe57499e0993b9fd9d36118c2
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

DENND5B HPN MED13

2.90e-04193303503a979328c68b096680b71359a26f02fafdff35
ToppCellSmart-seq2-thymus_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DENND5B SPCS2 FBXW7

2.90e-04193303bd82961502db42a0c862d3a29a2babe8032384c8
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FZD6 ARSL HPN

2.90e-04193303979980369d2dbee9dc4770d72b93037abd7786eb
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PLA2R1 SPON2 SVEP1

2.94e-0419430399577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FZD6 ARSL HPN

2.94e-04194303c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND5B SPCS2 FBXW7

2.99e-04195303bb30ac112f8c42d113fa83a9b662e40c0685bb1e
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND5B SPCS2 FBXW7

2.99e-041953030b0615553b9a1b60d666d074ce4260919e2d5642
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FZD6 ARSL HPN

2.99e-0419530362d369a8af2b76a2553bc8ff9cb89a133b060123
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARSL HPN PROC

3.03e-041963030df0dbe60e6f643912e5ff30c22415a0513f9bf1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARSL HPN PROC

3.03e-04196303153326be031a58b720da4dab57edd8936d513f8e
ComputationalNeighborhood of TST

HGFAC HABP2 HPN PROC

7.68e-06104144GNF2_TST
ComputationalNeighborhood of LCAT

HGFAC HABP2 HPN PROC

1.54e-05124144GNF2_LCAT
ComputationalSerine proteases.

KLK6 HPN PROC

1.56e-0539143MODULE_109
ComputationalNeighborhood of HPN

HGFAC HABP2 HPN PROC

2.10e-05134144GNF2_HPN
ComputationalNeighborhood of HPX

HGFAC HABP2 HPN PROC

2.16e-05135144GNF2_HPX
ComputationalNeighborhood of CYP2B6

HGFAC HPN PROC

3.13e-0549143GNF2_CYP2B6
ComputationalNeighborhood of CEBPA

HGFAC HPN PROC

6.99e-0564143GNF2_CEBPA
ComputationalGenes in the cancer module 107.

KLK6 HPN PROC

1.31e-0479143MODULE_107
ComputationalGenes in the cancer module 172.

KLK6 HPN PROC

2.34e-0496143MODULE_172
ComputationalNeighborhood of GSTM1

HGFAC HPN PROC

3.40e-04109143GNF2_GSTM1
DiseaseThrombophilia due to thrombin defect

HABP2 PROC

2.42e-058282cv:C3160733
Diseaseretinal drusen

ENGASE SVEP1

1.08e-0351282EFO_1001155
Diseasecardiomyopathy (implicated_via_orthology)

JPH1 JPH2

2.07e-0371282DOID:0050700 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GLIGKWHLGLNCESA

ARSL

141

P51690
HSAILSCEGRGVWKG

CSMD1

3131

Q96PZ7
HGCSSWERGDKFRGV

C8orf58

41

Q8NAV2
CGHSWSGGKDRHGSS

FLG2

186

Q5D862
SWERKGHGGLSCGLE

FLG2

231

Q5D862
GGWEGGKAHGHGLCT

JPH2

16

Q9BR39
GGWEEGKAHGHGICT

JPH1

16

Q9HDC5
CHKGRVFAWGAGSEG

HERC6

91

Q8IVU3
ACGVAHAGWKGTLLG

LACC1

296

Q8IV20
ISWGDGCGRLHKPGV

HGFAC

616

Q04756
EEKELGWCGHLRLGL

NEURL2

71

Q9BR09
HLCGGSLLSGDWVLT

HPN

186

P05981
GKDGWLGGTHCVACL

PAQR4

76

Q8N4S7
LVGLVSWGEGCGLLH

PROC

416

P04070
DIGFWCPRHLKTSGG

FZD6

156

O60353
ECHISGWGVTETGKG

HABP2

446

Q14520
GKCLRTLVGHTGGVW

FBXW7

411

Q969H0
CGRWLGKGIDDGSLE

DENND5B

1026

Q6ZUT9
LGGDGRGWVRTHCCL

ENGASE

441

Q8NFI3
SPSGASGGHWLRDCK

ITPRIPL2

216

Q3MIP1
WGLCGGHCGRLGTKS

SPON2

286

Q9BUD6
GRIGHGELKDWSCLL

MED13

1866

Q9UHV7
TTTLCGENGHWLGGK

SVEP1

2476

Q4LDE5
HKWISYGSGGGDICE

PLA2R1

146

Q13018
LWGSLCAGSGRGEAE

ACVR2B

11

Q13705
FHCGGGLTDWKPSED

XIAP

301

P98170
HVRCSGLWGHGTAGR

RP1L1

431

Q8IWN7
GLWGHGTAGRERCSQ

RP1L1

436

Q8IWN7
CGTGSGRSGLLDKWK

SPCS2

26

Q15005
GRLGCGEAGSANRHW

nan

126

Q8N9P0
WHGGCLALAELGRRG

TBCD

416

Q9BTW9
WKLSSGHKLGGDEGT

UBXN8

126

O00124
TSCHILGWGKTADGD

KLK6

136

Q92876