Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF468 NOTCH1 ZNF689 NTN3 IKZF5 ZNF574 ZFP57 ZNF316	2.92e-05	1412	43	12	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF813 ZNF69 ZNF696 MYBBP1A ZNF468 ZNF865 ZNF689 NTN3 IKZF5 ZNF574 ZFP57 ZNF316	4.03e-05	1459	43	12	GO:0000977
GeneOntologyMolecularFunction	nodal binding	CFC1B CFC1	1.26e-04	8	43	2	GO:0038100
GeneOntologyMolecularFunction	glycosaminoglycan binding	HAPLN3 LAMC2 COLQ FGFBP3 PCSK6	2.66e-04	268	43	5	GO:0005539
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF813 MYBBP1A ZNF468 ZNF865 NOTCH1 ZNF689 NTN3 IKZF5 ZNF574 ZNF316	2.92e-04	1271	43	10	GO:0000987
GeneOntologyMolecularFunction	activin receptor binding	CFC1B CFC1	4.05e-04	14	43	2	GO:0070697
GeneOntologyMolecularFunction	heparin binding	LAMC2 COLQ FGFBP3 PCSK6	7.63e-04	192	43	4	GO:0008201
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF813 MYBBP1A ZNF468 ZNF865 ZNF689 NTN3 IKZF5 ZNF574 ZNF316	1.13e-03	1244	43	9	GO:0000978
GeneOntologyMolecularFunction	Notch binding	DLL1 NOTCH1	1.54e-03	27	43	2	GO:0005112
GeneOntologyMolecularFunction	transmembrane receptor protein serine/threonine kinase binding	CFC1B CFC1	1.54e-03	27	43	2	GO:0070696
GeneOntologyMolecularFunction	receptor serine/threonine kinase binding	CFC1B CFC1	2.58e-03	35	43	2	GO:0033612
GeneOntologyMolecularFunction	zinc ion binding	MYBBP1A KMT2B PRICKLE3 TRIM44 PDZRN3 ZCCHC13 IKZF5	2.72e-03	891	43	7	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	ADCY10 MYBBP1A KMT2B PRICKLE3 TRIM44 PDZRN3 ZCCHC13 IKZF5	3.46e-03	1189	43	8	GO:0046914
GeneOntologyMolecularFunction	actinin binding	MICALL2 PDLIM1	3.87e-03	43	43	2	GO:0042805
GeneOntologyMolecularFunction	sulfur compound binding	LAMC2 COLQ FGFBP3 PCSK6	5.05e-03	323	43	4	GO:1901681
GeneOntologyMolecularFunction	transcription coregulator activity	MYBBP1A LIMD1 FHL3 PDLIM1 NOTCH1	6.91e-03	562	43	5	GO:0003712
GeneOntologyBiologicalProcess	anterior/posterior pattern specification	CFC1B DLL1 NOTCH1 PCSK6 CRB2 WNT2B CFC1	6.12e-07	247	42	7	GO:0009952
GeneOntologyBiologicalProcess	heart looping	CFC1B DLL1 NOTCH1 CFC1	1.46e-05	73	42	4	GO:0001947
GeneOntologyBiologicalProcess	determination of left/right symmetry	CFC1B DLL1 NOTCH1 PCSK6 CFC1	1.48e-05	154	42	5	GO:0007368
GeneOntologyBiologicalProcess	left/right pattern formation	CFC1B DLL1 NOTCH1 PCSK6 CFC1	1.89e-05	162	42	5	GO:0060972
GeneOntologyBiologicalProcess	determination of heart left/right asymmetry	CFC1B DLL1 NOTCH1 CFC1	2.00e-05	79	42	4	GO:0061371
GeneOntologyBiologicalProcess	determination of bilateral symmetry	CFC1B DLL1 NOTCH1 PCSK6 CFC1	2.06e-05	165	42	5	GO:0009855
GeneOntologyBiologicalProcess	specification of symmetry	CFC1B DLL1 NOTCH1 PCSK6 CFC1	2.06e-05	165	42	5	GO:0009799
GeneOntologyBiologicalProcess	embryonic heart tube morphogenesis	CFC1B DLL1 NOTCH1 CFC1	2.10e-05	80	42	4	GO:0003143
GeneOntologyBiologicalProcess	left lung morphogenesis	CFC1B CFC1	2.42e-05	4	42	2	GO:0060460
GeneOntologyBiologicalProcess	camera-type eye morphogenesis	DLL1 NOTCH1 CRB2 WNT2B NAGLU	2.45e-05	171	42	5	GO:0048593
GeneOntologyBiologicalProcess	retina morphogenesis in camera-type eye	DLL1 NOTCH1 CRB2 NAGLU	3.34e-05	90	42	4	GO:0060042
GeneOntologyBiologicalProcess	left lung development	CFC1B CFC1	4.03e-05	5	42	2	GO:0060459
GeneOntologyBiologicalProcess	compartment pattern specification	DLL1 NOTCH1	4.03e-05	5	42	2	GO:0007386
GeneOntologyBiologicalProcess	negative regulation of inner ear auditory receptor cell differentiation	DLL1 NOTCH1	4.03e-05	5	42	2	GO:0045608
GeneOntologyBiologicalProcess	negative regulation of mechanoreceptor differentiation	DLL1 NOTCH1	4.03e-05	5	42	2	GO:0045632
GeneOntologyBiologicalProcess	negative regulation of inner ear receptor cell differentiation	DLL1 NOTCH1	4.03e-05	5	42	2	GO:2000981
GeneOntologyBiologicalProcess	inner ear receptor cell differentiation	DLL1 NOTCH1 OTOG NAGLU	4.31e-05	96	42	4	GO:0060113
GeneOntologyBiologicalProcess	regionalization	CFC1B DLL1 NOTCH1 PCSK6 CRB2 WNT2B CFC1	4.59e-05	478	42	7	GO:0003002
GeneOntologyBiologicalProcess	regulation of embryonic development	DLL1 NOTCH1 CRB2 WNT2B	4.86e-05	99	42	4	GO:0045995
GeneOntologyBiologicalProcess	cardiac atrium morphogenesis	CFC1B NOTCH1 CFC1	4.91e-05	35	42	3	GO:0003209
GeneOntologyBiologicalProcess	embryonic heart tube development	CFC1B DLL1 NOTCH1 CFC1	5.67e-05	103	42	4	GO:0035050
GeneOntologyBiologicalProcess	eye morphogenesis	DLL1 NOTCH1 CRB2 WNT2B NAGLU	5.69e-05	204	42	5	GO:0048592
GeneOntologyBiologicalProcess	mechanoreceptor differentiation	DLL1 NOTCH1 OTOG NAGLU	5.89e-05	104	42	4	GO:0042490
GeneOntologyBiologicalProcess	inner ear receptor cell fate commitment	DLL1 NOTCH1	6.04e-05	6	42	2	GO:0060120
GeneOntologyBiologicalProcess	auditory receptor cell fate commitment	DLL1 NOTCH1	6.04e-05	6	42	2	GO:0009912
GeneOntologyBiologicalProcess	inhibition of neuroepithelial cell differentiation	DLL1 NOTCH1	6.04e-05	6	42	2	GO:0002085
GeneOntologyBiologicalProcess	arterial endothelial cell differentiation	DLL1 NOTCH1	6.04e-05	6	42	2	GO:0060842
GeneOntologyBiologicalProcess	embryonic organ morphogenesis	CFC1B DLL1 NOTCH1 CRB2 NAGLU CFC1	7.28e-05	351	42	6	GO:0048562
GeneOntologyBiologicalProcess	pattern specification process	CFC1B DLL1 NOTCH1 PCSK6 CRB2 WNT2B CFC1	8.38e-05	526	42	7	GO:0007389
GeneOntologyBiologicalProcess	regulation of somitogenesis	DLL1 NOTCH1	8.45e-05	7	42	2	GO:0014807
GeneOntologyBiologicalProcess	cardiac atrium development	CFC1B NOTCH1 CFC1	8.53e-05	42	42	3	GO:0003230
GeneOntologyBiologicalProcess	segmentation	DLL1 NOTCH1 PCSK6 CRB2	1.13e-04	123	42	4	GO:0035282
GeneOntologyBiologicalProcess	camera-type eye photoreceptor cell differentiation	NOTCH1 CRB2 NAGLU	1.36e-04	49	42	3	GO:0060219
GeneOntologyBiologicalProcess	digestive tract morphogenesis	CFC1B NOTCH1 CFC1	2.36e-04	59	42	3	GO:0048546
GeneOntologyBiologicalProcess	regulation of inner ear auditory receptor cell differentiation	DLL1 NOTCH1	2.64e-04	12	42	2	GO:0045607
GeneOntologyBiologicalProcess	regulation of mechanoreceptor differentiation	DLL1 NOTCH1	2.64e-04	12	42	2	GO:0045631
GeneOntologyBiologicalProcess	regulation of inner ear receptor cell differentiation	DLL1 NOTCH1	2.64e-04	12	42	2	GO:2000980
GeneOntologyBiologicalProcess	cardiac chamber morphogenesis	CFC1B NOTCH1 NAGLU CFC1	3.18e-04	161	42	4	GO:0003206
GeneOntologyBiologicalProcess	skin epidermis development	TNFRSF19 DLL1 NOTCH1 NAGLU	3.57e-04	166	42	4	GO:0098773
GeneOntologyBiologicalProcess	left/right axis specification	DLL1 NOTCH1	3.63e-04	14	42	2	GO:0070986
GeneOntologyBiologicalProcess	mitral valve morphogenesis	NOTCH1 NAGLU	4.18e-04	15	42	2	GO:0003183
GeneOntologyBiologicalProcess	blood vessel endothelial cell differentiation	DLL1 NOTCH1	4.18e-04	15	42	2	GO:0060837
GeneOntologyBiologicalProcess	regulation of timing of cell differentiation	DLL1 NOTCH1	4.18e-04	15	42	2	GO:0048505
GeneOntologyBiologicalProcess	eye photoreceptor cell differentiation	NOTCH1 CRB2 NAGLU	4.25e-04	72	42	3	GO:0001754
GeneOntologyBiologicalProcess	heart morphogenesis	CFC1B DLL1 NOTCH1 NAGLU CFC1	4.69e-04	321	42	5	GO:0003007
GeneOntologyBiologicalProcess	mitral valve development	NOTCH1 NAGLU	4.77e-04	16	42	2	GO:0003174
GeneOntologyBiologicalProcess	negative regulation of epidermis development	DLL1 NOTCH1	4.77e-04	16	42	2	GO:0045683
GeneOntologyBiologicalProcess	negative regulation of epidermal cell differentiation	DLL1 NOTCH1	4.77e-04	16	42	2	GO:0045605
GeneOntologyBiologicalProcess	somitogenesis	DLL1 NOTCH1 CRB2	4.98e-04	76	42	3	GO:0001756
GeneOntologyBiologicalProcess	lung morphogenesis	CFC1B WNT2B CFC1	5.17e-04	77	42	3	GO:0060425
GeneOntologyBiologicalProcess	embryonic morphogenesis	CFC1B DLL1 NOTCH1 CRB2 WNT2B NAGLU CFC1	5.38e-04	713	42	7	GO:0048598
GeneOntologyBiologicalProcess	regulation of development, heterochronic	DLL1 NOTCH1	5.40e-04	17	42	2	GO:0040034
GeneOntologyBiologicalProcess	atrial septum morphogenesis	CFC1B CFC1	6.07e-04	18	42	2	GO:0060413
GeneOntologyBiologicalProcess	sensory organ morphogenesis	DLL1 NOTCH1 CRB2 WNT2B NAGLU	6.34e-04	343	42	5	GO:0090596
GeneOntologyBiologicalProcess	coronary vasculature development	CFC1B NOTCH1 CFC1	6.44e-04	83	42	3	GO:0060976
GeneOntologyBiologicalProcess	tissue morphogenesis	CFC1B DLL1 NOTCH1 CRB2 WNT2B NAGLU CFC1	7.26e-04	750	42	7	GO:0048729
GeneOntologyBiologicalProcess	liver development	CFC1B NOTCH1 NAGLU CFC1	7.47e-04	202	42	4	GO:0001889
GeneOntologyBiologicalProcess	epithelial cell fate commitment	DLL1 NOTCH1	7.51e-04	20	42	2	GO:0072148
GeneOntologyBiologicalProcess	maintenance of cell polarity	PDLIM1 CRB2	7.51e-04	20	42	2	GO:0030011
GeneOntologyBiologicalProcess	endoderm development	CFC1B NOTCH1 CFC1	7.64e-04	88	42	3	GO:0007492
GeneOntologyBiologicalProcess	hepaticobiliary system development	CFC1B NOTCH1 NAGLU CFC1	7.89e-04	205	42	4	GO:0061008
GeneOntologyBiologicalProcess	cardiac septum morphogenesis	CFC1B NOTCH1 CFC1	7.89e-04	89	42	3	GO:0060411
GeneOntologyBiologicalProcess	animal organ morphogenesis	LAMC2 CFC1B DLL1 NOTCH1 NTN3 CRB2 WNT2B NAGLU CFC1	8.64e-04	1269	42	9	GO:0009887
GeneOntologyBiologicalProcess	retina development in camera-type eye	DLL1 NOTCH1 CRB2 NAGLU	8.79e-04	211	42	4	GO:0060041
GeneOntologyBiologicalProcess	cardiac chamber development	CFC1B NOTCH1 NAGLU CFC1	8.94e-04	212	42	4	GO:0003205
GeneOntologyBiologicalProcess	embryonic organ development	CFC1B DLL1 NOTCH1 CRB2 NAGLU CFC1	8.99e-04	561	42	6	GO:0048568
GeneOntologyBiologicalProcess	retinal cone cell differentiation	NOTCH1 CRB2	9.11e-04	22	42	2	GO:0042670
GeneOntologyBiologicalProcess	somite development	DLL1 NOTCH1 CRB2	9.25e-04	94	42	3	GO:0061053
GeneOntologyBiologicalProcess	photoreceptor cell differentiation	NOTCH1 CRB2 NAGLU	9.83e-04	96	42	3	GO:0046530
GeneOntologyBiologicalProcess	neural retina development	NOTCH1 CRB2 NAGLU	1.17e-03	102	42	3	GO:0003407
GeneOntologyBiologicalProcess	cardiac left ventricle morphogenesis	NOTCH1 NAGLU	1.18e-03	25	42	2	GO:0003214
GeneOntologyBiologicalProcess	atrial septum development	CFC1B CFC1	1.18e-03	25	42	2	GO:0003283
GeneOntologyBiologicalProcess	astrocyte differentiation	DLL1 NOTCH1 NAGLU	1.27e-03	105	42	3	GO:0048708
GeneOntologyBiologicalProcess	regulation of anoikis	MYBBP1A NOTCH1	1.28e-03	26	42	2	GO:2000209
GeneOntologyBiologicalProcess	nodal signaling pathway	CFC1B CFC1	1.28e-03	26	42	2	GO:0038092
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	DLL1 FGFBP3 NOTCH1 PCSK6 CRB2	1.44e-03	412	42	5	GO:0090287
GeneOntologyBiologicalProcess	nephron tubule development	DLL1 NOTCH1 WNT2B	1.46e-03	110	42	3	GO:0072080
GeneOntologyBiologicalProcess	atrioventricular valve morphogenesis	NOTCH1 NAGLU	1.48e-03	28	42	2	GO:0003181
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	CFC1B DLL1 NOTCH1 WNT2B NAGLU CFC1	1.49e-03	619	42	6	GO:0002009
GeneOntologyBiologicalProcess	axis specification	DLL1 NOTCH1 PCSK6	1.57e-03	113	42	3	GO:0009798
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	CFC1B DLL1 NOTCH1 WNT2B CFC1	1.58e-03	421	42	5	GO:0060562
GeneOntologyBiologicalProcess	muscle structure development	DLL1 FHL3 PDLIM1 NOTCH1 ZNF689 NTN3 NAGLU	1.59e-03	858	42	7	GO:0061061
GeneOntologyBiologicalProcess	camera-type eye development	DLL1 NOTCH1 CRB2 WNT2B NAGLU	1.66e-03	426	42	5	GO:0043010
GeneOntologyBiologicalProcess	renal tubule development	DLL1 NOTCH1 WNT2B	1.70e-03	116	42	3	GO:0061326
GeneOntologyBiologicalProcess	inner ear development	DLL1 NOTCH1 OTOG NAGLU	1.72e-03	253	42	4	GO:0048839
GeneOntologyBiologicalProcess	nucleotide transmembrane transport	ADCY10 SLC25A47	1.81e-03	31	42	2	GO:1901679
GeneOntologyBiologicalProcess	muscle organ development	DLL1 FHL3 NOTCH1 ZNF689 NAGLU	1.84e-03	436	42	5	GO:0007517
GeneOntologyBiologicalProcess	atrioventricular valve development	NOTCH1 NAGLU	1.93e-03	32	42	2	GO:0003171
GeneOntologyBiologicalProcess	hair follicle development	TNFRSF19 NOTCH1 NAGLU	2.00e-03	123	42	3	GO:0001942
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	CFC1B NOTCH1 PCSK6 CRB2 CFC1	2.01e-03	445	42	5	GO:0141091
GeneOntologyCellularComponent	extracellular matrix	HAPLN3 LAMC2 COLQ FGFBP3 NTN3 PCSK6 WNT2B OTOG	4.95e-05	656	43	8	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	HAPLN3 LAMC2 COLQ FGFBP3 NTN3 PCSK6 WNT2B OTOG	5.05e-05	658	43	8	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	HAPLN3 LAMC2 COLQ FGFBP3 NTN3 PCSK6 WNT2B	9.45e-05	530	43	7	GO:0062023
GeneOntologyCellularComponent	adherens junction	LIMD1 DLL1 PDLIM1 NOTCH1	9.31e-04	212	43	4	GO:0005912
GeneOntologyCellularComponent	cell-cell junction	LIMD1 DLL1 MICALL2 PDLIM1 NOTCH1 CRB2	1.25e-03	591	43	6	GO:0005911
GeneOntologyCellularComponent	contractile actin filament bundle	FHL3 MICALL2 PDLIM1	1.39e-03	107	43	3	GO:0097517
GeneOntologyCellularComponent	stress fiber	FHL3 MICALL2 PDLIM1	1.39e-03	107	43	3	GO:0001725
GeneOntologyCellularComponent	actomyosin	FHL3 MICALL2 PDLIM1	1.79e-03	117	43	3	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	FHL3 MICALL2 PDLIM1	1.84e-03	118	43	3	GO:0032432
GeneOntologyCellularComponent	basement membrane	LAMC2 COLQ NTN3	2.02e-03	122	43	3	GO:0005604
GeneOntologyCellularComponent	apical plasma membrane	ADCY10 DLL1 NOTCH1 CRB2 OTOG	3.12e-03	487	43	5	GO:0016324
GeneOntologyCellularComponent	anchoring junction	LIMD1 DLL1 FHL3 MICALL2 PDLIM1 NOTCH1 CRB2	3.50e-03	976	43	7	GO:0070161
MousePheno	abnormal direction of heart looping	CFC1B DLL1 PCSK6 CFC1	9.07e-07	38	28	4	MP:0004252
MousePheno	abnormal direction of embryo turning	CFC1B DLL1 CFC1	2.03e-06	13	28	3	MP:0004190
MousePheno	total anomalous pulmonary venous connection, intracardiac	CFC1B CFC1	3.87e-06	2	28	2	MP:0010443
MousePheno	abnormal heart looping	CFC1B KMT2B DLL1 PCSK6 CFC1	6.41e-06	135	28	5	MP:0000269
MousePheno	abnormal heart development	CFC1B KMT2B DLL1 NOTCH1 PCSK6 CRB2 CFC1	6.53e-06	372	28	7	MP:0000267
MousePheno	abnormal left-right axis patterning	CFC1B NOTCH1 PCSK6 CFC1	9.05e-06	67	28	4	MP:0001706
MousePheno	common atrium	CFC1B PCSK6 CFC1	1.42e-05	24	28	3	MP:0010406
MousePheno	unbalanced complete common atrioventricular canal	CFC1B CFC1	2.32e-05	4	28	2	MP:0011673
MousePheno	total anomalous pulmonary venous connection	CFC1B CFC1	2.32e-05	4	28	2	MP:0010441
MousePheno	heterotaxia	CFC1B DLL1 PCSK6 CFC1	2.92e-05	90	28	4	MP:0004133
MousePheno	left-sided isomerism	CFC1B PCSK6 CFC1	4.13e-05	34	28	3	MP:0000542
MousePheno	superior-inferior ventricles	CFC1B CFC1	8.07e-05	7	28	2	MP:0011254
MousePheno	abnormal developmental patterning	CFC1B KMT2B DLL1 NOTCH1 PCSK6 CRB2 CFC1	1.09e-04	577	28	7	MP:0002084
MousePheno	abnormal embryo turning	CFC1B KMT2B DLL1 CRB2 CFC1	1.26e-04	251	28	5	MP:0001700
MousePheno	accessory spleen	CFC1B CFC1	1.38e-04	9	28	2	MP:0003342
MousePheno	dextrocardia	CFC1B PCSK6 CFC1	1.41e-04	51	28	3	MP:0000644
MousePheno	abnormal lung position or orientation	CFC1B PCSK6 CFC1	1.96e-04	57	28	3	MP:0010853
MousePheno	situs inversus	CFC1B DLL1 CFC1	2.28e-04	60	28	3	MP:0002766
MousePheno	abnormal notochord morphology	DLL1 NOTCH1 CRB2	2.64e-04	63	28	3	MP:0002825
MousePheno	d-loop transposition of the great arteries	CFC1B CFC1	2.98e-04	13	28	2	MP:0011665
MousePheno	heart right ventricle hypoplasia	CFC1B CFC1	3.47e-04	14	28	2	MP:0010422
MousePheno	anomalous pulmonary venous connection	CFC1B CFC1	4.00e-04	15	28	2	MP:0010440
MousePheno	abnormal heart position or orientation	CFC1B PCSK6 CFC1	4.24e-04	74	28	3	MP:0006065
MousePheno	abnormal truncus arteriosus septation	CFC1B PCSK6 CFC1	6.15e-04	84	28	3	MP:0010454
MousePheno	atrial septal defect	CFC1B PCSK6 CFC1	7.05e-04	88	28	3	MP:0010403
MousePheno	mesocardia	CFC1B CFC1	7.19e-04	20	28	2	MP:0000650
MousePheno	abnormal azygos vein morphology	CFC1B CFC1	7.19e-04	20	28	2	MP:0011569
MousePheno	abnormal cardiovascular development	CFC1B KMT2B DLL1 NOTCH1 PCSK6 CRB2 CFC1	8.16e-04	802	28	7	MP:0002925
MousePheno	abnormal somite development	KMT2B DLL1 NOTCH1 CRB2	9.40e-04	222	28	4	MP:0001688
MousePheno	ventricular hypoplasia	CFC1B NOTCH1 CFC1	9.93e-04	99	28	3	MP:0000279
MousePheno	right pulmonary isomerism	CFC1B CFC1	1.13e-03	25	28	2	MP:0000531
MousePheno	decreased heart right ventricle size	CFC1B CFC1	1.13e-03	25	28	2	MP:0003649
MousePheno	complete atrioventricular septal defect	CFC1B CFC1	1.22e-03	26	28	2	MP:0010413
MousePheno	abnormal interatrial septum morphology	CFC1B PCSK6 CFC1	1.24e-03	107	28	3	MP:0000282
MousePheno	abnormal crista ampullaris morphology	OTOG NAGLU	1.42e-03	28	28	2	MP:0004249
MousePheno	abnormal left lung morphology	CFC1B CFC1	1.42e-03	28	28	2	MP:0009569
MousePheno	spontaneous skin ulceration	LAMC2 NAGLU	1.52e-03	29	28	2	MP:0001209
MousePheno	absent spleen	CFC1B CFC1	1.52e-03	29	28	2	MP:0000690
MousePheno	right-sided isomerism	CFC1B CFC1	1.63e-03	30	28	2	MP:0000508
MousePheno	abnormal foregut morphology	PCSK6 CRB2	1.63e-03	30	28	2	MP:0000474
MousePheno	right-sided stomach	CFC1B CFC1	1.74e-03	31	28	2	MP:0010808
MousePheno	abnormal semicircular canal ampulla morphology	OTOG NAGLU	1.85e-03	32	28	2	MP:0008488
MousePheno	abnormal gastrulation	CFC1B KMT2B DLL1 CRB2 CFC1	2.16e-03	469	28	5	MP:0001695
MousePheno	vascular ring	CFC1B CFC1	2.21e-03	35	28	2	MP:0010466
MousePheno	abnormal rostral-caudal axis patterning	KMT2B DLL1 NOTCH1	2.27e-03	132	28	3	MP:0005221
MousePheno	abnormal somatic sensory system morphology	DLL1 PRICKLE3 NOTCH1 NTN3 OTOG NAGLU	2.29e-03	702	28	6	MP:0000959
MousePheno	abnormal stomach position or orientation	CFC1B CFC1	2.34e-03	36	28	2	MP:0010807
MousePheno	abnormal cardiac outflow tract development	CFC1B PCSK6 CFC1	2.37e-03	134	28	3	MP:0006126
Domain	ZINC_FINGER_C2H2_2	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF598 ZNF865 ZNF689 IKZF5 ZNF574 ZFP57 ZNF316	1.13e-08	775	43	13	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF598 ZNF865 ZNF689 IKZF5 ZNF574 ZFP57 ZNF316	1.16e-08	777	43	13	PS00028
Domain	Znf_C2H2-like	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF598 ZNF865 ZNF689 IKZF5 ZNF574 ZFP57 ZNF316	1.55e-08	796	43	13	IPR015880
Domain	Znf_C2H2	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF598 ZNF865 ZNF689 IKZF5 ZNF574 ZFP57 ZNF316	1.77e-08	805	43	13	IPR007087
Domain	ZnF_C2H2	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF598 ZNF865 ZNF689 IKZF5 ZNF574 ZFP57 ZNF316	1.85e-08	808	43	13	SM00355
Domain	-	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF865 ZNF689 IKZF5 ZNF574 ZFP57 ZNF316	2.64e-08	679	43	12	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF865 ZNF689 IKZF5 ZNF574 ZFP57 ZNF316	3.35e-08	694	43	12	IPR013087
Domain	EGF-like_dom	LAMC2 CFC1B DLL1 NOTCH1 PCSK6 CRB2 OTOG CFC1	8.64e-08	249	43	8	IPR000742
Domain	zf-C2H2	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF865 ZNF689 ZNF574 ZFP57 ZNF316	3.30e-07	693	43	11	PF00096
Domain	LIM	LIMD1 FHL3 MICALL2 PDLIM1 PRICKLE3	5.13e-07	69	43	5	PF00412
Domain	-	LIMD1 FHL3 MICALL2 PDLIM1 PRICKLE3	5.51e-07	70	43	5	2.10.110.10
Domain	LIM_DOMAIN_2	LIMD1 FHL3 MICALL2 PDLIM1 PRICKLE3	5.92e-07	71	43	5	PS50023
Domain	Znf_LIM	LIMD1 FHL3 MICALL2 PDLIM1 PRICKLE3	5.92e-07	71	43	5	IPR001781
Domain	LIM_DOMAIN_1	LIMD1 FHL3 MICALL2 PDLIM1 PRICKLE3	5.92e-07	71	43	5	PS00478
Domain	LIM	LIMD1 FHL3 MICALL2 PDLIM1 PRICKLE3	5.92e-07	71	43	5	SM00132
Domain	EGF	LAMC2 CFC1B DLL1 NOTCH1 PCSK6 CRB2 CFC1	1.00e-06	235	43	7	SM00181
Domain	EGF_1	LAMC2 CFC1B DLL1 NOTCH1 NTN3 CRB2 CFC1	1.73e-06	255	43	7	PS00022
Domain	EGF-like_CS	LAMC2 CFC1B DLL1 NOTCH1 NTN3 CRB2 CFC1	2.01e-06	261	43	7	IPR013032
Domain	EGF_2	LAMC2 CFC1B DLL1 NOTCH1 NTN3 CRB2 CFC1	2.23e-06	265	43	7	PS01186
Domain	zf-C2H2_6	ZNF813 ZNF69 PLAGL2 ZNF468 ZNF865 ZNF574 ZNF316	6.81e-06	314	43	7	PF13912
Domain	EGF_3	CFC1B DLL1 NOTCH1 CRB2 OTOG CFC1	1.54e-05	235	43	6	PS50026
Domain	CFC	CFC1B CFC1	1.55e-05	3	43	2	PF09443
Domain	Cryptic/Cripto_CFC-dom	CFC1B CFC1	1.55e-05	3	43	2	IPR019011
Domain	KRAB	ZNF813 ZNF69 ZNF223 ZNF468 ZNF689 ZFP57 ZNF316	1.60e-05	358	43	7	PS50805
Domain	KRAB	ZNF813 ZNF69 ZNF223 ZNF468 ZNF689 ZFP57 ZNF316	1.60e-05	358	43	7	PF01352
Domain	KRAB	ZNF813 ZNF69 ZNF223 ZNF468 ZNF689 ZFP57 ZNF316	1.94e-05	369	43	7	SM00349
Domain	KRAB	ZNF813 ZNF69 ZNF223 ZNF468 ZNF689 ZFP57 ZNF316	1.97e-05	370	43	7	IPR001909
Domain	Growth_fac_rcpt_	LAMC2 DLL1 NOTCH1 NTN3 PCSK6	2.84e-05	156	43	5	IPR009030
Domain	hEGF	DLL1 NOTCH1 CRB2	3.58e-05	28	43	3	PF12661
Domain	-	PDZRN3 PDZRN4	4.63e-04	14	43	2	3.90.890.10
Domain	SIAH-type	PDZRN3 PDZRN4	6.09e-04	16	43	2	IPR013323
Domain	TRAF-like	PDZRN3 PDZRN4	1.38e-03	24	43	2	IPR008974
Domain	EGF_Ca-bd_CS	DLL1 NOTCH1 CRB2	1.44e-03	97	43	3	IPR018097
Domain	EGF_CA	DLL1 NOTCH1 CRB2	1.53e-03	99	43	3	PS01187
Domain	ASX_HYDROXYL	DLL1 NOTCH1 CRB2	1.57e-03	100	43	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	DLL1 NOTCH1 CRB2	1.86e-03	106	43	3	IPR000152
Domain	EGF_LAM_2	LAMC2 NTN3	2.16e-03	30	43	2	PS50027
Domain	EGF_LAM_1	LAMC2 NTN3	2.16e-03	30	43	2	PS01248
Domain	EGF_CA	DLL1 NOTCH1 CRB2	2.77e-03	122	43	3	SM00179
Domain	EGF-like_Ca-bd_dom	DLL1 NOTCH1 CRB2	2.90e-03	124	43	3	IPR001881
Domain	Laminin_EGF	LAMC2 NTN3	2.94e-03	35	43	2	PF00053
Domain	EGF_Lam	LAMC2 NTN3	2.94e-03	35	43	2	SM00180
Domain	EGF	DLL1 NOTCH1 CRB2	3.04e-03	126	43	3	PF00008
Domain	Laminin_EGF	LAMC2 NTN3	3.45e-03	38	43	2	IPR002049
Domain	PDZ	PDLIM1 PDZRN3 PDZRN4	4.17e-03	141	43	3	PF00595
Domain	PDZ	PDLIM1 PDZRN3 PDZRN4	4.77e-03	148	43	3	SM00228
Domain	-	PDLIM1 PDZRN3 PDZRN4	4.95e-03	150	43	3	2.30.42.10
Domain	PDZ	PDLIM1 PDZRN3 PDZRN4	5.05e-03	151	43	3	PS50106
Domain	PDZ	PDLIM1 PDZRN3 PDZRN4	5.14e-03	152	43	3	IPR001478
Pathway	BIOCARTA_NOTCH_PATHWAY	DLL1 NOTCH1	3.80e-05	6	23	2	MM1584
Pathway	BIOCARTA_NOTCH_PATHWAY	DLL1 NOTCH1	3.80e-05	6	23	2	M22074
Pathway	REACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT	DLL1 NOTCH1	5.32e-05	7	23	2	M27199
Pathway	WP_SOMITOGENESIS_IN_THE_CONTEXT_OF_SPONDYLOCOSTAL_DYSOSTOSIS	DLL1 NOTCH1	9.10e-05	9	23	2	M39869
Pathway	WP_GENE_REGULATORY_NETWORK_MODELLING_SOMITOGENESIS	DLL1 NOTCH1	1.14e-04	10	23	2	MM15839
Pathway	WP_GENE_REGULATORY_NETWORK_MODELING_SOMITOGENESIS	DLL1 NOTCH1	1.39e-04	11	23	2	M39647
Pathway	BIOCARTA_HES_PATHWAY	DLL1 NOTCH1	1.66e-04	12	23	2	MM1562
Pathway	BIOCARTA_HES_PATHWAY	DLL1 NOTCH1	1.66e-04	12	23	2	M22042
Pathway	WP_MIR127_IN_MESENDODERM_DIFFERENTIATION	CFC1B CFC1	1.66e-04	12	23	2	MM15910
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	DLL1 NOTCH1	1.96e-04	13	23	2	M47423
Pathway	BIOCARTA_PS1_PATHWAY	DLL1 NOTCH1	2.29e-04	14	23	2	MM1459
Pathway	BIOCARTA_PS1_PATHWAY	DLL1 NOTCH1	2.29e-04	14	23	2	M16173
Pathway	REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER	DLL1 NOTCH1	2.64e-04	15	23	2	M27202
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	DLL1 NOTCH1	3.01e-04	16	23	2	M47424
Pathway	WP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION	DLL1 NOTCH1	3.41e-04	17	23	2	M39389
Pathway	REACTOME_SIGNALING_BY_NODAL	PCSK6 CFC1	6.31e-04	23	23	2	M511
Pathway	WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING	DLL1 NOTCH1	8.72e-04	27	23	2	M39545
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	DLL1 NOTCH1 WNT2B	8.96e-04	118	23	3	M39852
Pathway	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	DLL1 NOTCH1	1.15e-03	31	23	2	M592
Pathway	REACTOME_SIGNALING_BY_NOTCH	DLL1 NOTCH1	1.82e-03	39	23	2	MM14604
Pathway	WP_BREAST_CANCER_PATHWAY	DLL1 NOTCH1 WNT2B	1.93e-03	154	23	3	M39739
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	DLL1 NOTCH1 WNT2B	2.19e-03	161	23	3	M39770
Pathway	WP_NOTCH_SIGNALING_WP268	DLL1 NOTCH1	2.42e-03	45	23	2	M39571
Pathway	WP_NOTCH_SIGNALING_PATHWAY	DLL1 NOTCH1	2.52e-03	46	23	2	MM15971
Pathway	PID_PS1_PATHWAY	DLL1 NOTCH1	2.52e-03	46	23	2	M70
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	DLL1 NOTCH1	2.63e-03	47	23	2	M7946
Pathway	WP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY	NOTCH1 WNT2B	2.74e-03	48	23	2	M39427
Pathway	REACTOME_SIGNALING_BY_NOTCH3	DLL1 NOTCH1	2.86e-03	49	23	2	M618
Pathway	REACTOME_SOMITOGENESIS	DLL1 NOTCH1	3.59e-03	55	23	2	M48032
Pathway	WP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM	DLL1 NOTCH1	3.85e-03	57	23	2	M48326
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	DLL1 NOTCH1	3.98e-03	58	23	2	M29616
Pathway	PID_NOTCH_PATHWAY	DLL1 NOTCH1	4.12e-03	59	23	2	M17
Pathway	WP_NOTCH_SIGNALING_WP61	DLL1 NOTCH1	4.40e-03	61	23	2	M39540
Pathway	WP_DYRK1A_INVOLVEMENT_REGARDING_CELL_PROLIFERATION_IN_BRAIN_DEVELOPMENT	DLL1 NOTCH1	4.54e-03	62	23	2	M45532
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2	DLL1 NOTCH1	4.68e-03	63	23	2	M27862
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF696 ZNF223 ZNF468 KMT2B DLL1 NOTCH1 ZNF689	5.24e-03	1387	23	7	M734
Pathway	REACTOME_FORMATION_OF_PARAXIAL_MESODERM	DLL1 NOTCH1	5.59e-03	69	23	2	M46439
Pathway	REACTOME_SIGNALING_BY_NOTCH1	DLL1 NOTCH1	6.40e-03	74	23	2	M616
Pubmed	Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry.	CFC1B DLL1 NOTCH1 CFC1	2.01e-09	14	43	4	17210915
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	PLAGL2 LIMD1 DLL1 ZNF598 PDLIM1 PRICKLE3 ZNF689 IKZF5 ZFP57	5.24e-07	808	43	9	20412781
Pubmed	Maternal Cripto is critical for proper development of the mouse placenta and the placental vasculature.	CFC1B NOTCH1 CFC1	7.93e-07	15	43	3	33730615
Pubmed	Tbx1 regulates population, proliferation and cell fate determination of otic epithelial cells.	DLL1 NOTCH1 WNT2B	7.93e-07	15	43	3	17074316
Pubmed	Notch1 induces enhanced expression of Delta-like-1 in the U251MG glioma cell line.	DLL1 NOTCH1	1.49e-06	2	43	2	19724883
Pubmed	Alteration of Delta-like ligand 1 and Notch 1 receptor in various placental disorders with special reference to early onset preeclampsia.	DLL1 NOTCH1	1.49e-06	2	43	2	26014475
Pubmed	Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer.	DLL1 NOTCH1	1.49e-06	2	43	2	22249198
Pubmed	Notch1 endocytosis is induced by ligand and is required for signal transduction.	DLL1 NOTCH1	1.49e-06	2	43	2	26522918
Pubmed	NOTCH, a new signaling pathway implicated in holoprosencephaly.	DLL1 NOTCH1	1.49e-06	2	43	2	21196490
Pubmed	Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.	CFC1B CFC1	1.49e-06	2	43	2	11327798
Pubmed	Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.	CFC1B CFC1	1.49e-06	2	43	2	11024280
Pubmed	Cis-interactions between Notch and Delta generate mutually exclusive signalling states.	DLL1 NOTCH1	1.49e-06	2	43	2	20418862
Pubmed	Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells.	DLL1 NOTCH1	1.49e-06	2	43	2	17878313
Pubmed	Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM.	DLL1 NOTCH1	1.49e-06	2	43	2	25468943
Pubmed	The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.	CFC1B CFC1	1.49e-06	2	43	2	11174844
Pubmed	Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.	CFC1B CFC1	1.49e-06	2	43	2	11062482
Pubmed	Regulation of Notch1 signaling by Delta-like ligand 1 intracellular domain through physical interaction.	DLL1 NOTCH1	1.49e-06	2	43	2	21643850
Pubmed	Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.	CFC1B DLL1 CFC1	2.31e-06	21	43	3	16291790
Pubmed	Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse.	CFC1B PCSK6 CFC1	3.50e-06	24	43	3	18171685
Pubmed	Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway.	DLL1 NOTCH1	4.48e-06	3	43	2	21602795
Pubmed	The COX-2 selective inhibitor-independent COX-2 effect on colon carcinoma cells is associated with the Delta1/Notch1 pathway.	DLL1 NOTCH1	4.48e-06	3	43	2	18320325
Pubmed	Identification and characterization of PDZRN3 and PDZRN4 genes in silico.	PDZRN3 PDZRN4	4.48e-06	3	43	2	15010864
Pubmed	Verification of microRNA expression in human endometrial adenocarcinoma.	DLL1 NOTCH1	4.48e-06	3	43	2	27039384
Pubmed	Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling.	DLL1 NOTCH1	4.48e-06	3	43	2	23072809
Pubmed	Horizontal basal cells self-govern their neurogenic potential during injury-induced regeneration of the olfactory epithelium.	DLL1 NOTCH1	4.48e-06	3	43	2	37260223
Pubmed	Notch signaling confers antigen-presenting cell functions on mast cells.	DLL1 NOTCH1	4.48e-06	3	43	2	19130928
Pubmed	Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.	CFC1B CFC1	4.48e-06	3	43	2	16835440
Pubmed	Activation of Notch signal pathway is associated with a poorer prognosis in acute myeloid leukemia.	DLL1 NOTCH1	4.48e-06	3	43	2	20812035
Pubmed	Delta-like 1-Lysine613 regulates notch signaling.	DLL1 NOTCH1	4.48e-06	3	43	2	21985982
Pubmed	Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.	DLL1 NOTCH1	4.48e-06	3	43	2	23839946
Pubmed	The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway.	DLL1 NOTCH1	4.48e-06	3	43	2	12050162
Pubmed	The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity.	DLL1 NOTCH1	4.48e-06	3	43	2	18676613
Pubmed	Both Notch1 and its ligands in B cells promote antibody production.	DLL1 NOTCH1	4.48e-06	3	43	2	28863329
Pubmed	Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation.	DLL1 NOTCH1	4.48e-06	3	43	2	34519870
Pubmed	Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity.	DLL1 NOTCH1	4.48e-06	3	43	2	30110645
Pubmed	Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation.	DLL1 NOTCH1	4.48e-06	3	43	2	15781650
Pubmed	Cancer stem cell and embryonic development-associated molecules contribute to prognostic significance in ovarian cancer.	DLL1 NOTCH1	4.48e-06	3	43	2	22080880
Pubmed	Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells.	DLL1 NOTCH1	4.48e-06	3	43	2	15976178
Pubmed	Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.	PLAGL2 MYBBP1A LIMD1 NOTCH1	5.01e-06	91	43	4	21194568
Pubmed	Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.	DLL1 NOTCH1	8.94e-06	4	43	2	18824585
Pubmed	Notch signalling pathway mediates hair cell development in mammalian cochlea.	DLL1 NOTCH1	8.94e-06	4	43	2	10080181
Pubmed	Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes.	DLL1 NOTCH1	8.94e-06	4	43	2	22390640
Pubmed	Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.	DLL1 NOTCH1	8.94e-06	4	43	2	9315665
Pubmed	Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.	DLL1 NOTCH1	8.94e-06	4	43	2	32820046
Pubmed	No evidence for a functional role of bi-directional Notch signaling during angiogenesis.	DLL1 NOTCH1	8.94e-06	4	43	2	23300864
Pubmed	Role of recycling, Mindbomb1 association, and exclusion from lipid rafts of δ-like 4 for effective Notch signaling to drive T cell development.	DLL1 NOTCH1	8.94e-06	4	43	2	23162128
Pubmed	Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1.	CFC1B CFC1	8.94e-06	4	43	2	9576836
Pubmed	Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B.	DLL1 NOTCH1	8.94e-06	4	43	2	16317090
Pubmed	DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries.	DLL1 NOTCH1	8.94e-06	4	43	2	19144989
Pubmed	Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A.	DLL1 NOTCH1	8.94e-06	4	43	2	19383720
Pubmed	Cripto in tumors and embryo development.	CFC1B CFC1	8.94e-06	4	43	2	11825688
Pubmed	Different downstream pathways for Notch signaling are required for gliogenic and chondrogenic specification of mouse mesencephalic neural crest cells.	DLL1 NOTCH1	8.94e-06	4	43	2	18299190
Pubmed	The Notch signalling pathway in hair growth.	DLL1 NOTCH1	8.94e-06	4	43	2	9858728
Pubmed	Role of the EGF-CFC gene cripto in cell differentiation and embryo development.	CFC1B CFC1	8.94e-06	4	43	2	11992720
Pubmed	Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane.	DLL1 NOTCH1	8.94e-06	4	43	2	9244302
Pubmed	Notch controls the survival of memory CD4+ T cells by regulating glucose uptake.	DLL1 NOTCH1	8.94e-06	4	43	2	25501905
Pubmed	Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos.	DLL1 NOTCH1	8.94e-06	4	43	2	11044625
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF813 ZNF696 FNDC3A MYBBP1A ZNF468 LIMD1 PRICKLE3 ZNF574 ZNF316	1.34e-05	1203	43	9	29180619
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	DLL1 NOTCH1 ZNF689 NTN3 WNT2B	1.45e-05	251	43	5	29031500
Pubmed	The notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse.	DLL1 NOTCH1	1.49e-05	5	43	2	11713346
Pubmed	Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.	DLL1 NOTCH1	1.49e-05	5	43	2	11006133
Pubmed	Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb.	CFC1B CFC1	1.49e-05	5	43	2	25224222
Pubmed	Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms.	DLL1 NOTCH1	1.49e-05	5	43	2	19110448
Pubmed	The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity.	DLL1 NOTCH1	1.49e-05	5	43	2	15902259
Pubmed	Apoptosome inactivation rescues proneural and neural cells from neurodegeneration.	DLL1 NOTCH1	1.49e-05	5	43	2	15257302
Pubmed	Botch promotes neurogenesis by antagonizing Notch.	DLL1 NOTCH1	1.49e-05	5	43	2	22445366
Pubmed	Immunohistochemical expression of Notch signaling in the lining epithelium of periapical cysts.	DLL1 NOTCH1	1.49e-05	5	43	2	21238798
Pubmed	Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.	DLL1 NOTCH1	1.49e-05	5	43	2	30181175
Pubmed	Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain.	DLL1 NOTCH1	1.49e-05	5	43	2	12175503
Pubmed	A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation.	CFC1B CFC1	1.49e-05	5	43	2	9053319
Pubmed	The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts.	DLL1 NOTCH1	1.49e-05	5	43	2	12354787
Pubmed	Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells.	DLL1 NOTCH1	1.49e-05	5	43	2	19682396
Pubmed	Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.	DLL1 NOTCH1	1.49e-05	5	43	2	10879540
Pubmed	Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.	DLL1 NOTCH1	1.49e-05	5	43	2	20554499
Pubmed	GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.	CFC1B CFC1	2.23e-05	6	43	2	17991893
Pubmed	Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.	DLL1 NOTCH1	2.23e-05	6	43	2	11731257
Pubmed	Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.	DLL1 NOTCH1	2.23e-05	6	43	2	19603167
Pubmed	Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.	DLL1 NOTCH1	2.23e-05	6	43	2	10958687
Pubmed	GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.	DLL1 NOTCH1	2.23e-05	6	43	2	34698766
Pubmed	The CD46-Jagged1 interaction is critical for human TH1 immunity.	DLL1 NOTCH1	2.23e-05	6	43	2	23086448
Pubmed	Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands.	DLL1 NOTCH1	2.23e-05	6	43	2	28089369
Pubmed	A role of the cryptic gene in the correct establishment of the left-right axis.	CFC1B CFC1	2.23e-05	6	43	2	10574770
Pubmed	Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation.	DLL1 NOTCH1	2.23e-05	6	43	2	9882480
Pubmed	Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ+CD8αα+ T cells.	DLL1 NOTCH1	2.23e-05	6	43	2	31071093
Pubmed	Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.	CFC1B CFC1	2.23e-05	6	43	2	12052855
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	PLAGL2 LIMD1 FHL3 PRICKLE3 TRIM44 PCSK6 ZFP57	2.42e-05	709	43	7	22988430
Pubmed	Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.	DLL1 NOTCH1	3.12e-05	7	43	2	24711412
Pubmed	Human ligands of the Notch receptor.	DLL1 NOTCH1	3.12e-05	7	43	2	10079256
Pubmed	Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm.	DLL1 NOTCH1	3.12e-05	7	43	2	9153393
Pubmed	Presenilin-1 regulates neuronal differentiation during neurogenesis.	DLL1 NOTCH1	3.12e-05	7	43	2	10821758
Pubmed	Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.	DLL1 NOTCH1	3.12e-05	7	43	2	15866159
Pubmed	Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.	CFC1B CFC1	3.12e-05	7	43	2	10521397
Pubmed	Genome-wide analysis of Müller glial differentiation reveals a requirement for Notch signaling in postmitotic cells to maintain the glial fate.	DLL1 NOTCH1	3.12e-05	7	43	2	21829655
Pubmed	Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors.	DLL1 NOTCH1	3.12e-05	7	43	2	11076679
Pubmed	Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock.	DLL1 NOTCH1	3.12e-05	7	43	2	35429490
Pubmed	Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos.	CFC1B CFC1	3.12e-05	7	43	2	19906859
Pubmed	GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.	DLL1 NOTCH1	3.12e-05	7	43	2	32060138
Pubmed	The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.	DLL1 NOTCH1	3.12e-05	7	43	2	30289388
Pubmed	Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon.	DLL1 NOTCH1	3.12e-05	7	43	2	18997111
Pubmed	Impaired expression of Notch signaling genes in aged human skeletal muscle.	DLL1 NOTCH1	3.12e-05	7	43	2	17301032
Interaction	NOTCH2 interactions	ZNF813 ZNF696 DLL1 ZNF598 ZNF865 NOTCH1 ZNF689 ZNF574 CFC1 ZNF316	9.36e-09	423	41	10	int:NOTCH2
Interaction	FBLN2 interactions	ZNF696 LAMC2 ZNF865 ZNF316	9.70e-06	66	41	4	int:FBLN2
Interaction	ZNF707 interactions	ZNF696 NOTCH1 ZNF689 ZNF316	1.98e-05	79	41	4	int:ZNF707
Interaction	MFNG interactions	HAPLN3 DLL1 NOTCH1	2.21e-05	27	41	3	int:MFNG
Interaction	LTBP2 interactions	ZNF696 ZNF865 ZNF574 ZNF316	2.65e-05	85	41	4	int:LTBP2
Interaction	CACNG5 interactions	ZNF865 ZNF574 ZNF316	7.90e-05	41	41	3	int:CACNG5
Interaction	CFC1 interactions	NOTCH1 PCSK6 NAGLU CFC1	1.23e-04	126	41	4	int:CFC1
Interaction	TRIM28 interactions	ZNF813 FNDC3A MYBBP1A ZNF223 ZNF468 FHL3 ZNF598 NOTCH1 ZNF689 ZFP57 ZNF316	1.26e-04	1474	41	11	int:TRIM28
Interaction	TNFRSF19 interactions	ZNF696 TNFRSF19 ZNF865	1.71e-04	53	41	3	int:TNFRSF19
Interaction	TEX19 interactions	LIMD1 ZNF865 ZNF316	1.80e-04	54	41	3	int:TEX19
Interaction	ZNF169 interactions	ZNF865 ZNF689 ZNF316	1.80e-04	54	41	3	int:ZNF169
Interaction	LNX2 interactions	FHL3 PDZRN3 NOTCH1 PDZRN4	2.06e-04	144	41	4	int:LNX2
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF813 ZNF223 ZNF468 KMT2B ZNF865 ZNF574	8.11e-04	1192	43	6	chr19q13
Cytoband	2q21.1	CFC1B CFC1	1.37e-03	58	43	2	2q21.1
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF813 ZNF69 ZNF696 PLAGL2 ZNF223 ZNF468 ZNF598 ZNF865 ZNF689 IKZF5 ZNF574 ZFP57 ZNF316	3.61e-10	718	35	13	28
GeneFamily	LIM domain containing	LIMD1 FHL3 MICALL2 PDLIM1 PRICKLE3	9.37e-08	59	35	5	1218
GeneFamily	PDZ domain containing	PDLIM1 PDZRN3 PDZRN4	3.13e-03	152	35	3	1220
GeneFamily	Ring finger proteins	TRIM44 PDZRN3 PDZRN4	1.59e-02	275	35	3	58
Coexpression	NABA_MATRISOME	HAPLN3 LAMC2 CFC1B COLQ FGFBP3 NTN3 PCSK6 WNT2B OTOG CFC1	4.08e-06	1008	43	10	MM17056
Coexpression	NABA_MATRISOME	HAPLN3 LAMC2 CFC1B COLQ FGFBP3 NTN3 PCSK6 WNT2B OTOG CFC1	4.78e-06	1026	43	10	M5889
Coexpression	NABA_BASEMENT_MEMBRANES	LAMC2 COLQ NTN3	3.89e-05	40	43	3	M5887
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2A	HAPLN3 COLQ PDZRN3 FGFBP3 NOTCH1 PCSK6 CRB2	5.01e-05	600	43	7	M39055
Coexpression	NABA_CORE_MATRISOME	HAPLN3 LAMC2 COLQ NTN3 OTOG	7.81e-05	270	43	5	MM17057
Coexpression	NABA_CORE_MATRISOME	HAPLN3 LAMC2 COLQ NTN3 OTOG	8.52e-05	275	43	5	M5884
ToppCell	normal_Lung-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	ZNF69 ZNF696 TNFRSF19 ZNF598 PRICKLE3	6.40e-07	171	43	5	f49dfe11ae66d82125b577c48345a13683d7bb7b
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LAMC2 CRB2 WNT2B CFC1 PDZRN4	9.96e-07	187	43	5	8e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LAMC2 CRB2 WNT2B CFC1 PDZRN4	1.02e-06	188	43	5	9655a4c47b644a870017d349b99063e17dbae572
ToppCell	facs-Marrow-Granulocytes-3m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHL3 FGFBP3 PCSK6 ZNF574	1.51e-05	155	43	4	9b26ade19488511c72b64335011d2dcd81e8f167
ToppCell	facs-Marrow-Granulocytes-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHL3 FGFBP3 PCSK6 ZNF574	1.51e-05	155	43	4	cd2f3ad4f131588325a667b6724e530d821fbe30
ToppCell	facs-Marrow-Granulocytes-3m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHL3 FGFBP3 PCSK6 ZNF574	1.51e-05	155	43	4	4246709e27703b94529369abbed5763e4002e79d
ToppCell	367C-Fibroblasts-Fibroblast-F-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ADCY10 PCSK6 WNT2B PDZRN4	1.97e-05	166	43	4	1cc291a04f4144abba4aca7badeb7776db05d903
ToppCell	367C-Fibroblasts-Fibroblast-F\|367C / Donor, Lineage, Cell class and subclass (all cells)	ADCY10 PCSK6 WNT2B PDZRN4	1.97e-05	166	43	4	2887f4f0c218cbcbcc82eef27aa4ee714b35cddb
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFC1B CRB2 CFC1 PDZRN4	2.53e-05	177	43	4	0912a291cff32a4ff8a2d7680ed1a1cd867fb90f
ToppCell	wk_15-18-Mesenchymal-Mesothelial-intermediate_mesothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	2.65e-05	179	43	4	b1f085e4c8d65d5cdbfaf2db80343638abb08979
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ZNF813 PLAGL2 PRICKLE3 ZNF316	2.71e-05	180	43	4	c3d1521ac90f2e3fc31158e6e61907e05c37af39
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Late_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	LAMC2 WNT2B CFC1 PDZRN4	2.83e-05	182	43	4	f8257c884393f168f605d371e0840cfca8d3657e
ToppCell	wk_20-22-Mesenchymal-Mesothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	2.95e-05	184	43	4	804f8a41cd6b1361448872bf352bf0a38a0fac66
ToppCell	wk_20-22-Mesenchymal-Mesothelial-Late_mesothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	2.95e-05	184	43	4	60dd055c2e2e92b838ac649c12e8cccd9c3b1b71
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	3.01e-05	185	43	4	492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell	wk_15-18-Mesenchymal-Mesothelial-Early_mesothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	3.08e-05	186	43	4	ae4b6ecfc1850c0a01a11b9dd9718880f2a24fe0
ToppCell	wk_15-18-Mesenchymal-Mesothelial-Late_mesothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	3.21e-05	188	43	4	38a53f99f1876359983936403aefca93281d10fd
ToppCell	wk_15-18-Mesenchymal-Mesothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	3.41e-05	191	43	4	b5374674312ff5803a1d369f5533027532344679
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	3.41e-05	191	43	4	4c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCell	wk_08-11-Mesenchymal-Mesothelial-intermediate_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	3.48e-05	192	43	4	ac9e5288ecd4b1e142f2e15a1fcd11c8eb9e15cd
ToppCell	wk_08-11-Mesenchymal-Mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CRB2 WNT2B CFC1 PDZRN4	3.70e-05	195	43	4	9016a44b521214546a55a822ebdef5b5312206d2
Disease	double outlet right ventricle (implicated_via_orthology)	CFC1B CFC1	5.93e-06	3	42	2	DOID:6406 (implicated_via_orthology)
Disease	right atrial isomerism (implicated_via_orthology)	CFC1B CFC1	1.18e-05	4	42	2	DOID:0060856 (implicated_via_orthology)
Disease	dextro-looped transposition of the great arteries (implicated_via_orthology)	CFC1B CFC1	1.18e-05	4	42	2	DOID:0060770 (implicated_via_orthology)
Disease	Scoliosis, unspecified	DLL1 NOTCH1	5.51e-05	8	42	2	C0036439
Disease	visceral heterotaxy (is_implicated_in)	CFC1B CFC1	1.29e-04	12	42	2	DOID:0050545 (is_implicated_in)
Disease	visceral heterotaxy (implicated_via_orthology)	CFC1B CFC1	1.28e-03	37	42	2	DOID:0050545 (implicated_via_orthology)
Disease	Alzheimer disease, gastroesophageal reflux disease	ZNF223 MICALL2 ZNF689	4.19e-03	228	42	3	EFO_0003948, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
PAHFTGRYCEHDQRR	CFC1B	106	P0CG36
AHRCDHCRGRDFIPY	ADCY10	961	Q96PN6
PAHFTGRYCEHDQRR	CFC1	106	P0CG37
AAGLHRYLRDFCGCH	NAGLU	86	P54802
HLERCDFAPARCRHA	PDZRN3	101	Q9UPQ7
CDYRARGCGHSVRLH	PDZRN4	81	Q6ZMN7
DCIRCHRAYCGDGHR	COLQ	396	Q9Y215
ARHQCAYRGHPERCA	FGFBP3	86	Q8TAT2
HDRVASFYCECPHGR	NOTCH1	351	P46531
GPRHRRLHRYDVFCF	HAPLN3	246	Q96S86
DGHRCYPLEDHLFCH	LIMD1	641	Q9UGP4
PCHHGATCRNLADRY	CRB2	116	Q5IJ48
HLADGRLYHRSCFRC	MICALL2	201	Q8IY33
GYFGDTAARRCRRCH	PCSK6	736	P29122
LECERCRHAYHPACL	KMT2B	1266	Q9UMN6
RCHLCPFASAYERHL	IKZF5	111	Q9H5V7
HHLCRARRYCHDLGE	MYBBP1A	881	Q9BQG0
AGRHCHYCREGFYRD	NTN3	346	O00634
KVYCGRHHAECLRPR	PRICKLE3	236	O43900
YEDRHFHEGCFRCCR	FHL3	56	Q13643
CHERGHRYVCECARG	DLL1	496	O00548
REHLCDRLNPGCFYR	FNDC3A	621	Q9Y2H6
GFYRHRERDRCLPCN	LAMC2	71	Q13753
DRHRHPECYVCTDCG	PDLIM1	276	O00151
YAHLCRRHGLPVDFR	OTOG	756	Q6ZRI0
CGFCYCRRHAEAHRQ	TRIM44	36	Q96DX7
FGTYRHCLAHICRLR	SLC25A47	71	Q6Q0C1
HCLAHICRLRYGNPD	SLC25A47	76	Q6Q0C1
HPCDHCDRRFYTRKD	PLAGL2	191	Q9UPG8
HALCHPCRLRYDVVG	CHST13	251	Q8NET6
QRLHLGERAYRCEHC	ZNF865	951	P0CJ78
HRAHTGERPYNCDDC	ZNF223	391	Q9UK11
YHRRMHLGERPFCCT	ZFP57	136	Q9NU63
HFPYRCQECGVRFHR	ZNF574	576	Q6ZN55
RRTHHGENPYECREC	ZNF696	256	Q9H7X3
ERRQHCYTCGRLGHL	ZCCHC13	86	Q8WW36
HRRCHTGEKPYRCNE	ZNF813	261	Q6ZN06
LRRDHYFCHFCDSDG	ZNF598	206	Q86UK7
RRVHSGERPYACEHC	ZNF689	336	Q96CS4
RYHAGERPHRCADCG	ZNF316	711	A6NFI3
FDRPQLHEYAHRACC	TNFRSF19	221	Q9NS68
CGKAFHSPRCYRRHE	ZNF69	281	Q9UC07
RYLACHRRCHTGEKP	ZNF468	256	Q5VIY5
CSCDPYTRGRHHDQR	WNT2B	166	Q93097