Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein domain specific binding	SHANK1 EZR WBP1 IRS2 RARA SGIP1 SHANK2 KHDRBS3 ATXN2 TJP1	6.34e-06	875	40	10	GO:0019904
GeneOntologyMolecularFunction	nuclear retinoid X receptor binding	NSD1 RARB RARG	1.28e-05	23	40	3	GO:0046965
GeneOntologyMolecularFunction	synaptic receptor adaptor activity	SHANK1 SHANK2	2.34e-05	4	40	2	GO:0030160
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	SHANK1 IRS2 SHANK2	1.72e-04	54	40	3	GO:0030159
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	NSD1 RARB RARG	1.82e-04	55	40	3	GO:0042974
GeneOntologyMolecularFunction	SH3 domain binding	SHANK1 SGIP1 SHANK2 KHDRBS3	1.89e-04	143	40	4	GO:0017124
GeneOntologyMolecularFunction	structural constituent of postsynaptic density	SHANK1 SHANK2	2.13e-04	11	40	2	GO:0098919
GeneOntologyMolecularFunction	nuclear receptor activity	RARA RARB RARG	2.35e-04	60	40	3	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	RARA RARB RARG	2.47e-04	61	40	3	GO:0098531
GeneOntologyMolecularFunction	histone H3K36 methyltransferase activity	NSD1 ASH1L	3.01e-04	13	40	2	GO:0046975
GeneOntologyMolecularFunction	structural constituent of postsynaptic specialization	SHANK1 SHANK2	3.01e-04	13	40	2	GO:0098879
GeneOntologyMolecularFunction	transcription factor binding	NSD1 SIN3A RARA RARB RARG PPRC1 PITX2	6.63e-04	753	40	7	GO:0008134
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	NSD1 SIN3A RARB RARG PITX2	1.40e-03	417	40	5	GO:0061629
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	SHANK1 NSD1 IRS2 SIN3A SHANK2 EPN1 PPRC1 SYNE2	1.84e-03	1160	40	8	GO:0030674
GeneOntologyMolecularFunction	structural constituent of postsynapse	SHANK1 SHANK2	1.87e-03	32	40	2	GO:0099186
GeneOntologyMolecularFunction	signaling adaptor activity	SHANK1 IRS2 SHANK2	2.19e-03	129	40	3	GO:0035591
GeneOntologyMolecularFunction	structural constituent of synapse	SHANK1 SHANK2	3.20e-03	42	40	2	GO:0098918
GeneOntologyMolecularFunction	chromatin binding	NSD1 SIN3A RARA RARG PITX2 ASH1L	3.30e-03	739	40	6	GO:0003682
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	NSD1 ASH1L	3.51e-03	44	40	2	GO:0140938
GeneOntologyMolecularFunction	molecular adaptor activity	SHANK1 NSD1 IRS2 SIN3A SHANK2 EPN1 PPRC1 SYNE2	4.83e-03	1356	40	8	GO:0060090
GeneOntologyMolecularFunction	ionotropic glutamate receptor binding	SHANK1 SHANK2	4.87e-03	52	40	2	GO:0035255
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	NSD1 SIN3A RARB RARG PITX2	5.86e-03	582	40	5	GO:0140297
GeneOntologyMolecularFunction	protein kinase A binding	EZR RARA	6.03e-03	58	40	2	GO:0051018
GeneOntologyMolecularFunction	nuclear receptor binding	NSD1 RARB RARG	6.19e-03	187	40	3	GO:0016922
GeneOntologyMolecularFunction	protein kinase binding	EZR PTPN23 IRS2 RARA RBBP6 ZBTB4	7.39e-03	873	40	6	GO:0019901
GeneOntologyMolecularFunction	zinc ion binding	NSD1 RARA RARB RARG RBBP6 ZMYM4	8.14e-03	891	40	6	GO:0008270
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	NSD1 ASH1L	8.20e-03	68	40	2	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	NSD1 ASH1L	8.43e-03	69	40	2	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	NSD1 ASH1L	8.91e-03	71	40	2	GO:0042054
GeneOntologyBiologicalProcess	multicellular organism growth	EZR RARA SGIP1 RARB RARG ATXN2 RBBP6	4.56e-07	249	40	7	GO:0035264
GeneOntologyBiologicalProcess	ventricular cardiac muscle cell differentiation	RARA RARB PITX2	6.41e-06	19	40	3	GO:0055012
GeneOntologyBiologicalProcess	developmental growth	EZR SIN3A RARA SGIP1 RARB RARG NRCAM RAPH1 ATXN2 RBBP6	6.81e-06	911	40	10	GO:0048589
GeneOntologyBiologicalProcess	head development	IRS2 SIN3A RARA RARB RARG NRCAM ATXN2 RAX SYNE2 PITX2	7.35e-06	919	40	10	GO:0060322
GeneOntologyBiologicalProcess	growth plate cartilage development	RARA RARB RARG	2.38e-05	29	40	3	GO:0003417
GeneOntologyBiologicalProcess	brain development	IRS2 SIN3A RARA RARB NRCAM ATXN2 RAX SYNE2 PITX2	3.09e-05	859	40	9	GO:0007420
GeneOntologyBiologicalProcess	embryonic hindlimb morphogenesis	RARB RARG PITX2	4.24e-05	35	40	3	GO:0035116
GeneOntologyBiologicalProcess	negative regulation of cartilage development	RARA RARB RARG	4.61e-05	36	40	3	GO:0061037
GeneOntologyBiologicalProcess	retinoic acid receptor signaling pathway	RARA RARB RARG	5.44e-05	38	40	3	GO:0048384
GeneOntologyBiologicalProcess	endochondral bone growth	RARA RARB RARG	5.88e-05	39	40	3	GO:0003416
GeneOntologyBiologicalProcess	limb development	RARA RARB RARG RAX PITX2	6.97e-05	224	40	5	GO:0060173
GeneOntologyBiologicalProcess	appendage development	RARA RARB RARG RAX PITX2	6.97e-05	224	40	5	GO:0048736
GeneOntologyBiologicalProcess	glandular epithelial cell development	RARA RARB RARG	7.90e-05	43	40	3	GO:0002068
GeneOntologyBiologicalProcess	bone growth	RARA RARB RARG	9.06e-05	45	40	3	GO:0098868
GeneOntologyBiologicalProcess	embryonic camera-type eye development	RARA RARG PITX2	9.06e-05	45	40	3	GO:0031076
GeneOntologyBiologicalProcess	growth	EZR SIN3A RARA SGIP1 RARB RARG NRCAM RAPH1 ATXN2 RBBP6	9.28e-05	1235	40	10	GO:0040007
GeneOntologyBiologicalProcess	trachea cartilage development	RARA RARG	1.02e-04	8	40	2	GO:0060534
GeneOntologyBiologicalProcess	cartilage development involved in endochondral bone morphogenesis	RARA RARB RARG	1.03e-04	47	40	3	GO:0060351
GeneOntologyBiologicalProcess	hindlimb morphogenesis	RARB RARG PITX2	1.17e-04	49	40	3	GO:0035137
GeneOntologyBiologicalProcess	positive regulation of early endosome to late endosome transport	EZR PTPN23	1.31e-04	9	40	2	GO:2000643
GeneOntologyBiologicalProcess	maintenance of postsynaptic density structure	SHANK1 SHANK2	1.31e-04	9	40	2	GO:0099562
GeneOntologyBiologicalProcess	epithelial cell development	EZR RARA RARB RARG TJP1	1.65e-04	269	40	5	GO:0002064
GeneOntologyBiologicalProcess	cell junction maintenance	SHANK1 SHANK2 TJP1	2.72e-04	65	40	3	GO:0034331
GeneOntologyBiologicalProcess	regulation of myelination	RARA RARB RARG	2.97e-04	67	40	3	GO:0031641
GeneOntologyBiologicalProcess	embryo development	NSD1 LAMA2 SIN3A RARA RARB RARG EPN1 TJP1 RBBP6 PITX2	3.21e-04	1437	40	10	GO:0009790
GeneOntologyBiologicalProcess	columnar/cuboidal epithelial cell development	RARA RARB RARG	3.24e-04	69	40	3	GO:0002066
GeneOntologyBiologicalProcess	forebrain development	SIN3A RARA RARB RAX SYNE2 PITX2	3.33e-04	489	40	6	GO:0030900
GeneOntologyBiologicalProcess	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	VPS37C PTPN23	3.79e-04	15	40	2	GO:0043328
GeneOntologyBiologicalProcess	central nervous system development	IRS2 SIN3A RARA RARB NRCAM ATXN2 RAX SYNE2 PITX2	3.86e-04	1197	40	9	GO:0007417
GeneOntologyBiologicalProcess	regulation of cell migration	LAMA2 JCAD PTPN23 IRS2 SIN3A TJP1 SYNE2 PITX2 FIGNL2	4.21e-04	1211	40	9	GO:0030334
GeneOntologyBiologicalProcess	endochondral bone morphogenesis	RARA RARB RARG	4.82e-04	79	40	3	GO:0060350
GeneOntologyBiologicalProcess	maintenance of postsynaptic specialization structure	SHANK1 SHANK2	4.90e-04	17	40	2	GO:0098880
GeneOntologyBiologicalProcess	regulation of cartilage development	RARA RARB RARG	5.19e-04	81	40	3	GO:0061035
GeneOntologyBiologicalProcess	regulation of sprouting angiogenesis	JCAD EPN1 TJP1	5.98e-04	85	40	3	GO:1903670
GeneOntologyBiologicalProcess	regulation of cell motility	LAMA2 JCAD PTPN23 IRS2 SIN3A TJP1 SYNE2 PITX2 FIGNL2	6.30e-04	1280	40	9	GO:2000145
GeneOntologyBiologicalProcess	gland development	EZR IRS2 RARA RARG PITX2 ASH1L	6.70e-04	558	40	6	GO:0048732
GeneOntologyBiologicalProcess	regulation of early endosome to late endosome transport	EZR PTPN23	6.82e-04	20	40	2	GO:2000641
GeneOntologyBiologicalProcess	embryonic organ development	RARA RARB RARG EPN1 RBBP6 PITX2	6.89e-04	561	40	6	GO:0048568
GeneOntologyBiologicalProcess	glandular epithelial cell differentiation	RARA RARB RARG	7.29e-04	91	40	3	GO:0002067
GeneOntologyBiologicalProcess	regulation of multicellular organism growth	EZR SGIP1 ATXN2	7.77e-04	93	40	3	GO:0040014
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	NSD1 EZR SIN3A RARA RARB RARG ZBTB4 PITX2	8.03e-04	1053	40	8	GO:0000122
GeneOntologyBiologicalProcess	regulation of locomotion	LAMA2 JCAD PTPN23 IRS2 SIN3A TJP1 SYNE2 PITX2 FIGNL2	8.16e-04	1327	40	9	GO:0040012
GeneOntologyBiologicalProcess	trachea development	RARA RARG	8.27e-04	22	40	2	GO:0060438
GeneOntologyBiologicalProcess	regulation of cell size	EZR SIN3A RARG NRCAM	9.26e-04	225	40	4	GO:0008361
GeneOntologyBiologicalProcess	vocalization behavior	SHANK1 SHANK2	9.85e-04	24	40	2	GO:0071625
GeneOntologyBiologicalProcess	cellular component maintenance	SHANK1 SHANK2 TJP1	9.87e-04	101	40	3	GO:0043954
GeneOntologyBiologicalProcess	late endosome to vacuole transport via multivesicular body sorting pathway	VPS37C PTPN23	1.25e-03	27	40	2	GO:0032511
GeneOntologyBiologicalProcess	negative regulation of chondrocyte differentiation	RARB RARG	1.25e-03	27	40	2	GO:0032331
GeneOntologyBiologicalProcess	regulation of developmental growth	EZR SIN3A SGIP1 NRCAM ATXN2	1.26e-03	421	40	5	GO:0048638
GeneOntologyBiologicalProcess	female pregnancy	RARA DAZAP1 EPN1 ASH1L	1.35e-03	249	40	4	GO:0007565
GeneOntologyBiologicalProcess	chordate embryonic development	SIN3A RARA RARG EPN1 TJP1 RBBP6 PITX2	1.62e-03	906	40	7	GO:0043009
GeneOntologyBiologicalProcess	hypothalamus development	RAX PITX2	1.65e-03	31	40	2	GO:0021854
GeneOntologyBiologicalProcess	bone development	RARA RARB RARG PITX2	1.67e-03	264	40	4	GO:0060348
GeneOntologyBiologicalProcess	positive regulation of neuron differentiation	SIN3A RARA NRCAM	1.74e-03	123	40	3	GO:0045666
GeneOntologyBiologicalProcess	negative regulation of stem cell proliferation	RARB RARG	1.75e-03	32	40	2	GO:2000647
GeneOntologyBiologicalProcess	bone morphogenesis	RARA RARB RARG	1.78e-03	124	40	3	GO:0060349
GeneOntologyBiologicalProcess	cell morphogenesis	SHANK1 LAMA2 EZR SIN3A NRCAM RAPH1 ATXN2 ZMYM4	1.80e-03	1194	40	8	GO:0000902
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	SIN3A RARA RARG EPN1 TJP1 RBBP6 PITX2	1.86e-03	929	40	7	GO:0009792
GeneOntologyBiologicalProcess	positive regulation of sprouting angiogenesis	JCAD TJP1	1.86e-03	33	40	2	GO:1903672
GeneOntologyBiologicalProcess	centrosome localization	EZR SYNE2	2.10e-03	35	40	2	GO:0051642
GeneOntologyBiologicalProcess	embryonic digestive tract development	RARB PITX2	2.10e-03	35	40	2	GO:0048566
GeneOntologyBiologicalProcess	microtubule organizing center localization	EZR SYNE2	2.22e-03	36	40	2	GO:0061842
GeneOntologyBiologicalProcess	eye development	RARA RARB RARG RAX PITX2	2.25e-03	480	40	5	GO:0001654
GeneOntologyBiologicalProcess	axon extension	SIN3A NRCAM RAPH1	2.27e-03	135	40	3	GO:0048675
GeneOntologyBiologicalProcess	visual system development	RARA RARB RARG RAX PITX2	2.31e-03	483	40	5	GO:0150063
GeneOntologyBiologicalProcess	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	VPS37C PTPN23	2.34e-03	37	40	2	GO:0043162
GeneOntologyBiologicalProcess	multi-organism reproductive process	RARA DAZAP1 EPN1 ASH1L	2.35e-03	290	40	4	GO:0044703
GeneOntologyBiologicalProcess	embryonic eye morphogenesis	RARB RARG	2.47e-03	38	40	2	GO:0048048
GeneOntologyBiologicalProcess	multi-multicellular organism process	RARA DAZAP1 EPN1 ASH1L	2.47e-03	294	40	4	GO:0044706
GeneOntologyBiologicalProcess	sensory system development	RARA RARB RARG RAX PITX2	2.48e-03	491	40	5	GO:0048880
GeneOntologyBiologicalProcess	limbic system development	RARA RAX PITX2	2.57e-03	141	40	3	GO:0021761
GeneOntologyBiologicalProcess	late endosome to vacuole transport	VPS37C PTPN23	2.60e-03	39	40	2	GO:0045324
GeneOntologyBiologicalProcess	developmental growth involved in morphogenesis	SIN3A RARG NRCAM RAPH1	2.62e-03	299	40	4	GO:0060560
GeneOntologyBiologicalProcess	developmental cell growth	SIN3A RARG NRCAM RAPH1	2.69e-03	301	40	4	GO:0048588
GeneOntologyBiologicalProcess	maintenance of synapse structure	SHANK1 SHANK2	2.73e-03	40	40	2	GO:0099558
GeneOntologyBiologicalProcess	embryonic limb morphogenesis	RARB RARG PITX2	2.94e-03	148	40	3	GO:0030326
GeneOntologyBiologicalProcess	embryonic appendage morphogenesis	RARB RARG PITX2	2.94e-03	148	40	3	GO:0035113
GeneOntologyBiologicalProcess	maintenance of blood-brain barrier	LAMA2 TJP1	3.01e-03	42	40	2	GO:0035633
GeneOntologyBiologicalProcess	postsynapse organization	SHANK1 EZR SHANK2 NRCAM	3.09e-03	313	40	4	GO:0099173
GeneOntologyBiologicalProcess	endosome transport via multivesicular body sorting pathway	VPS37C PTPN23	3.15e-03	43	40	2	GO:0032509
MousePheno	fusion of atlas and odontoid process	RARA RARB RARG	1.42e-06	10	33	3	MP:0010701
MousePheno	absent metoptic pillar	RARB RARG	5.40e-06	2	33	2	MP:0010705
MousePheno	abnormal odontoid process morphology	RARA RARB RARG	9.55e-06	18	33	3	MP:0004659
MousePheno	split cervical atlas	RARB RARG	3.23e-05	4	33	2	MP:0010702
MousePheno	split cervical axis	RARB RARG	3.23e-05	4	33	2	MP:0010703
MousePheno	abnormal optic canal morphology	RARB RARG	5.38e-05	5	33	2	MP:0010704
MousePheno	abnormal cervical axis morphology	RARA RARB RARG	6.82e-05	34	33	3	MP:0004608
MousePheno	decreased total retina thickness	RNF38 JCAD IRS2 SYNE2 PITX2	9.10e-05	197	33	5	MP:0011965
MousePheno	cervical vertebral transformation	RARA RARB RARG	1.20e-04	41	33	3	MP:0004615
MousePheno	cervical vertebral fusion	RARA RARB RARG	1.29e-04	42	33	3	MP:0004620
MousePheno	abnormal orbitosphenoid bone morphology	RARB RARG	1.50e-04	8	33	2	MP:0004457
MousePheno	abnormal total retina thickness	RNF38 JCAD IRS2 SYNE2 PITX2	1.63e-04	223	33	5	MP:0011963
MousePheno	narrow eye opening	RARA RARB RARG	2.18e-04	50	33	3	MP:0005287
MousePheno	abnormal cervical atlas morphology	RARA RARB RARG	2.31e-04	51	33	3	MP:0004607
MousePheno	decreased gonadotroph cell number	IRS2 PITX2	2.93e-04	11	33	2	MP:0008335
MousePheno	abnormal eyelid aperture	RARA RARB RARG	3.56e-04	59	33	3	MP:0003671
MousePheno	fusion of vertebral arches	RARA RARB RARG	3.93e-04	61	33	3	MP:0004613
MousePheno	fusion of atlas and occipital bones	RARB RARG	4.15e-04	13	33	2	MP:0010728
MousePheno	abnormal cricoid cartilage morphology	RARA RARG	5.57e-04	15	33	2	MP:0002258
MousePheno	abnormal gonadotroph morphology	IRS2 PITX2	5.57e-04	15	33	2	MP:0008325
MousePheno	decreased mature ovarian follicle number	TBPL2 IRS2 DAZAP1	6.66e-04	73	33	3	MP:0002682
MousePheno	failure of superovulation	TBPL2 IRS2	8.08e-04	18	33	2	MP:0031422
MousePheno	abnormal orbit morphology	RARB RARG	8.08e-04	18	33	2	MP:0010030
MousePheno	abnormal lens development	RAX ZBTB4 PITX2	8.08e-04	78	33	3	MP:0005545
MousePheno	abnormal mature ovarian follicle morphology	TBPL2 IRS2 DAZAP1	8.08e-04	78	33	3	MP:0009364
MousePheno	abnormal long-term depression	LAMA2 RARB SHANK2	9.35e-04	82	33	3	MP:0001898
MousePheno	increased cholesterol level	LAMA2 PTPN23 IRS2 ATXN2 ZMYM4 TMEM51	1.01e-03	502	33	6	MP:0003982
MousePheno	abnormal lens morphology	SHANK1 SGIP1 RARB NRCAM RAX ZBTB4 PITX2	1.04e-03	699	33	7	MP:0001303
MousePheno	increased sterol level	LAMA2 PTPN23 IRS2 ATXN2 ZMYM4 TMEM51	1.04e-03	505	33	6	MP:0012226
Domain	Retinoic_acid_rcpt	RARA RARB RARG	3.63e-08	4	40	3	IPR003078
Domain	WBP1-like	WBP1 TMEM92	2.68e-05	4	40	2	IPR021684
Domain	WBP-1	WBP1 TMEM92	2.68e-05	4	40	2	PF11669
Domain	AWS	NSD1 ASH1L	4.45e-05	5	40	2	PS51215
Domain	AWS_dom	NSD1 ASH1L	4.45e-05	5	40	2	IPR006560
Domain	AWS	NSD1 ASH1L	4.45e-05	5	40	2	SM00570
Domain	zf-C4	RARA RARB RARG	1.30e-04	46	40	3	PF00105
Domain	NUCLEAR_REC_DBD_1	RARA RARB RARG	1.30e-04	46	40	3	PS00031
Domain	Znf_hrmn_rcpt	RARA RARB RARG	1.30e-04	46	40	3	IPR001628
Domain	Nuclear_hrmn_rcpt	RARA RARB RARG	1.30e-04	46	40	3	IPR001723
Domain	ZnF_C4	RARA RARB RARG	1.30e-04	46	40	3	SM00399
Domain	NUCLEAR_REC_DBD_2	RARA RARB RARG	1.30e-04	46	40	3	PS51030
Domain	-	RARA RARB RARG	1.38e-04	47	40	3	1.10.565.10
Domain	HOLI	RARA RARB RARG	1.47e-04	48	40	3	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	RARA RARB RARG	1.47e-04	48	40	3	IPR000536
Domain	Hormone_recep	RARA RARB RARG	1.47e-04	48	40	3	PF00104
Domain	-	RARA RARB RARG	2.46e-04	57	40	3	3.30.50.10
Domain	Znf_NHR/GATA	RARA RARB RARG	2.59e-04	58	40	3	IPR013088
Domain	OAR	RAX PITX2	4.61e-04	15	40	2	PF03826
Domain	OAR	RAX PITX2	5.27e-04	16	40	2	PS50803
Domain	Post-SET_dom	NSD1 ASH1L	5.27e-04	16	40	2	IPR003616
Domain	PostSET	NSD1 ASH1L	5.27e-04	16	40	2	SM00508
Domain	OAR_dom	RAX PITX2	5.27e-04	16	40	2	IPR003654
Domain	POST_SET	NSD1 ASH1L	5.27e-04	16	40	2	PS50868
Domain	SH3_2	SHANK1 SHANK2 TJP1	8.23e-04	86	40	3	IPR011511
Domain	SH3_2	SHANK1 SHANK2 TJP1	8.23e-04	86	40	3	PF07653
Domain	-	KHDRBS3 KHDC4	3.15e-03	39	40	2	3.30.1370.10
Domain	PDZ	SHANK1 SHANK2 TJP1	3.39e-03	141	40	3	PF00595
Domain	SET	NSD1 ASH1L	3.48e-03	41	40	2	PF00856
Domain	Znf_FYVE_PHD	NSD1 ZBTB4 ASH1L	3.81e-03	147	40	3	IPR011011
Domain	PDZ	SHANK1 SHANK2 TJP1	3.89e-03	148	40	3	SM00228
Domain	KH_dom_type_1	KHDRBS3 KHDC4	4.00e-03	44	40	2	IPR004088
Domain	-	SHANK1 SHANK2 TJP1	4.04e-03	150	40	3	2.30.42.10
Domain	PDZ	SHANK1 SHANK2 TJP1	4.11e-03	151	40	3	PS50106
Domain	PDZ	SHANK1 SHANK2 TJP1	4.19e-03	152	40	3	IPR001478
Domain	SET	NSD1 ASH1L	4.36e-03	46	40	2	SM00317
Domain	SET_dom	NSD1 ASH1L	5.13e-03	50	40	2	IPR001214
Domain	SET	NSD1 ASH1L	5.13e-03	50	40	2	PS50280
Pathway	WP_VITAMIN_A1_AND_A5X_PATHWAYS	RARA RARB RARG	1.25e-07	6	27	3	M48097
Pathway	PID_RXR_VDR_PATHWAY	RARA RARB RARG	1.58e-05	26	27	3	M162
Pathway	PID_RETINOIC_ACID_PATHWAY	RARA RARB RARG	2.46e-05	30	27	3	M207
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	RARA RARB RARG	2.46e-05	30	27	3	MM15866
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	RARA RARB RARG	3.29e-05	33	27	3	MM1448
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	RARA RARB RARG	3.60e-05	34	27	3	M16393
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	RARA RARB RARG	3.94e-05	35	27	3	M39488
Pathway	WP_NUCLEAR_RECEPTORS	RARA RARB RARG	5.05e-05	38	27	3	M39657
Pathway	WP_NUCLEAR_RECEPTORS	RARA RARB RARG	5.05e-05	38	27	3	MM15865
Pathway	WP_VITAMIN_A_AND_CAROTENOID_METABOLISM	RARA RARB RARG	7.35e-05	43	27	3	M39554
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RARA RARB RARG	7.35e-05	43	27	3	M27443
Pathway	WP_RETINOL_METABOLISM	RARA RARB RARG	7.88e-05	44	27	3	MM15851
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	RARA RARB RARG	1.02e-04	48	27	3	MM14987
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RARA RARB RARG	1.09e-04	49	27	3	MM15186
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	RARA RARB RARG	1.38e-04	53	27	3	M8276
Pathway	WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM	RARA RARB RARG	1.99e-04	60	27	3	M40048
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	TBPL2 LAMA2 EZR IRS2 SIN3A RARA RARB RARG NRCAM	9.64e-04	1432	27	9	M509
Pathway	REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS	RARA RARB RARG	1.59e-03	122	27	3	M29689
Pathway	WP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV	SHANK1 TJP1	1.80e-03	33	27	2	M39875
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMA2 IRS2	1.80e-03	33	27	2	M39503
Pubmed	Impairing retinoic acid signalling in the neural crest cells is sufficient to alter entire eye morphogenesis.	RARA RARB RARG PITX2	3.13e-10	10	40	4	18539269
Pubmed	Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants.	RARA RARB RARG	1.41e-09	3	40	3	7607068
Pubmed	Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.	RARA RARB RARG	1.41e-09	3	40	3	7607067
Pubmed	Impaired distribution of retinoic acid receptors in the hindgut-tailgut region of murine embryos with anorectal malformations.	RARA RARB RARG	1.41e-09	3	40	3	11172439
Pubmed	Cloning of several genes coding for retinoic acid nuclear receptors in the mouse embryonal carcinoma cell line PCC7-MZ1.	RARA RARB RARG	1.41e-09	3	40	3	8383767
Pubmed	Retinoic acid receptor gamma: specific immunodetection and phosphorylation.	RARA RARB RARG	1.41e-09	3	40	3	1655807
Pubmed	A redundant oncogenic potential of the retinoic receptor (RAR) alpha, beta and gamma isoforms in acute promyelocytic leukemia.	RARA RARB RARG	1.41e-09	3	40	3	17252005
Pubmed	Retinoic acid down-regulation of fibronectin and retinoic acid receptor alpha proteins in NIH-3T3 cells. Blocks of this response by ras transformation.	RARA RARB RARG	1.41e-09	3	40	3	8626453
Pubmed	Function of retinoic acid receptor gamma in the mouse.	RARA RARB RARG	1.41e-09	3	40	3	8388780
Pubmed	Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart.	RARA RARB RARG	1.41e-09	3	40	3	9659935
Pubmed	Retinoids and vertebrate development.	RARA RARB RARG	1.41e-09	3	40	3	7910825
Pubmed	Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo.	RARA RARB RARG	1.41e-09	3	40	3	10842077
Pubmed	Altered expression of retinoic acid (RA) receptor mRNAs in the fetal mouse secondary palate by all-trans and 13-cis RAs: implications for RA-induced teratogenesis.	RARA RARB RARG	1.41e-09	3	40	3	10100049
Pubmed	Both retinoic acid receptors alpha (RARalpha) and gamma (RARgamma) are able to initiate mouse upper-lip skin glandular metaplasia.	RARA RARB RARG	1.41e-09	3	40	3	9699718
Pubmed	Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues.	RARA RARB RARG	1.41e-09	3	40	3	1283441
Pubmed	Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs.	RARA RARB RARG	1.41e-09	3	40	3	36446525
Pubmed	Association of retinoic acid receptor genes with meningomyelocele.	RARA RARB RARG	1.41e-09	3	40	3	21254357
Pubmed	Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes.	RARA RARB RARG	1.41e-09	3	40	3	1655630
Pubmed	Arg278, but not Lys229 or Lys236, plays an important role in the binding of retinoic acid by retinoic acid receptor gamma.	RARA RARB RARG	1.41e-09	3	40	3	9852056
Pubmed	The molecular and genetic dissection of the retinoid signalling pathway.	RARA RARB RARG	1.41e-09	3	40	3	8276261
Pubmed	Requirement of retinoic acid receptor isotypes alpha, beta, and gamma during the initial steps of neural differentiation of PCC7 cells.	RARA RARB RARG	1.41e-09	3	40	3	15831518
Pubmed	Immunolocalization of retinoic acid receptors in rat, mouse and human ovary and uterus.	RARA RARB RARG	1.41e-09	3	40	3	8136307
Pubmed	Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts.	RARA RARB RARG	1.41e-09	3	40	3	24357724
Pubmed	Retinoic acid and mouse skin morphogenesis. I. Expression pattern of retinoic acid receptor genes during hair vibrissa follicle, plantar, and nasal gland development.	RARA RARB RARG	1.41e-09	3	40	3	8027572
Pubmed	Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin.	RARA RARB RARG	1.41e-09	3	40	3	2544807
Pubmed	[Genetic expression and morphogenesis of the skin in vertebrates].	RARA RARB RARG	1.41e-09	3	40	3	8099268
Pubmed	Specificity of retinoid receptor gene expression in mouse cervical epithelia.	RARA RARB RARG	1.41e-09	3	40	3	8156902
Pubmed	Characterization of retinoic acid receptor-deficient keratinocytes.	RARA RARB RARG	1.41e-09	3	40	3	10748128
Pubmed	Strain difference and mode of inheritance of the susceptibility to passive cutaneous anaphylaxis mediated by allogeneic IgE antibody in the mouse.	RARA RARB RARG	1.41e-09	3	40	3	2737701
Pubmed	Immunohistochemical localization of the retinoic Acid receptors in human prostate.	RARA RARB RARG	1.41e-09	3	40	3	12399530
Pubmed	Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.	RARA RARB RARG	1.41e-09	3	40	3	29848550
Pubmed	HACE1: A novel repressor of RAR transcriptional activity.	RARA RARB RARG	5.63e-09	4	40	3	19350571
Pubmed	Association of peroxisome proliferator-activated receptors/retinoic acid receptors with renal diseases.	RARA RARB RARG	5.63e-09	4	40	3	24050824
Pubmed	Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton.	RARA RARB RARG	5.63e-09	4	40	3	7626396
Pubmed	Immunolocalization of enzymes, binding proteins, and receptors sufficient for retinoic acid synthesis and signaling during the hair cycle.	RARA RARB RARG	5.63e-09	4	40	3	17363914
Pubmed	Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled.	RARA RARB RARG	5.63e-09	4	40	3	12093741
Pubmed	Identification of a retinoid receptor response element in the human aldehyde dehydrogenase-2 promoter.	RARA RARB RARG	5.63e-09	4	40	3	14691372
Pubmed	Retinoic acid regulates the human methionine sulfoxide reductase A (MSRA) gene via two distinct promoters.	RARA RARB RARG	5.63e-09	4	40	3	18845237
Pubmed	The retinoic acid receptors RARalpha and RARgamma are required for inner ear development.	RARA RARB RARG	5.63e-09	4	40	3	12464434
Pubmed	Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms.	RARA RARB RARG	5.63e-09	4	40	3	9376317
Pubmed	Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse.	RARA RARB RARG	5.63e-09	4	40	3	2556642
Pubmed	Retinoic acid signalling in the development of branchial arches.	RARA RARB RARG	5.63e-09	4	40	3	15380252
Pubmed	Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway.	RARA RARB RARG	5.63e-09	4	40	3	10869350
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NSD1 EZR PTPN23 SIN3A SMG7 RAPH1 TJP1 RBBP6 ZMYM4	1.01e-08	549	40	9	38280479
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 RNF38 EZR JCAD RARB DAZAP1 NRCAM TJP1 PPRC1 ZMYM4 ZBTB4 ASH1L	1.32e-08	1285	40	12	35914814
Pubmed	Retinoic acid signaling regulates murine bronchial tubule formation.	RARA RARB RARG	1.41e-08	5	40	3	12834868
Pubmed	An essential set of basic DNA response elements is required for receptor-dependent transcription of the lecithin:retinol acyltransferase (Lrat) gene.	RARA RARB RARG	1.41e-08	5	40	3	19665987
Pubmed	Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development.	RARA RARB RARG	1.41e-08	5	40	3	9053308
Pubmed	Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos.	RARA RARB RARG	1.41e-08	5	40	3	8174226
Pubmed	Regulation of the Oct-4 gene by nuclear receptors.	RARA RARB RARG	1.41e-08	5	40	3	8152920
Pubmed	Retinoic acid receptor beta 2 mRNA is elevated by retinoic acid in vivo in susceptible regions of mid-gestation mouse embryos.	RARA RARB RARG	1.41e-08	5	40	3	1334737
Pubmed	High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice.	RARA RARB RARG	1.41e-08	5	40	3	8394014
Pubmed	Initiation of retinoid signaling in primitive streak mouse embryos: spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis.	RARA RARB RARG	1.41e-08	5	40	3	9097025
Pubmed	Retinal dysplasia and degeneration in RARbeta2/RARgamma2 compound mutant mice.	RARA RARB RARG	1.41e-08	5	40	3	8681798
Pubmed	Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.	RARA RARB RARG	1.41e-08	5	40	3	19006694
Pubmed	ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome.	RARA RARB RARG	1.41e-08	5	40	3	19345331
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	RNF38 WBP1 JCAD SIN3A TMEM92 EPN1 ATXN2 RBBP6	2.78e-08	430	40	8	35044719
Pubmed	Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes.	RARA RARB RARG	2.81e-08	6	40	3	11328745
Pubmed	The isolation and characterization of purified heterocomplexes of recombinant retinoic acid receptor and retinoid X receptor ligand binding domains.	RARA RARB RARG	2.81e-08	6	40	3	9153406
Pubmed	Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning.	RARA RARB RARG	2.81e-08	6	40	3	11493525
Pubmed	Spatial distributions of retinoic acid receptor gene transcripts in the prenatal mouse inner ear.	RARA RARB RARG	2.81e-08	6	40	3	9548551
Pubmed	Functional specificity of the two retinoic acid receptor RAR and RXR families in myogenesis.	RARA RARB RARG	2.81e-08	6	40	3	9464546
Pubmed	Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.	RARA RARB RARG	2.81e-08	6	40	3	20557428
Pubmed	RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells.	RARA RARB RARG	2.81e-08	6	40	3	8801169
Pubmed	A decade of molecular biology of retinoic acid receptors.	RARA RARB RARG	2.81e-08	6	40	3	8801176
Pubmed	The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development.	RARA RARB RARG	2.81e-08	6	40	3	9806918
Pubmed	Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis.	RARA RARB RARG	2.81e-08	6	40	3	1966045
Pubmed	A genetic dissection of the retinoid signalling pathway in the mouse.	RARA RARB RARG	2.81e-08	6	40	3	10604193
Pubmed	Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos.	RARA RARB RARG	2.81e-08	6	40	3	1849812
Pubmed	Retinoid signaling distinguishes a subpopulation of olfactory receptor neurons in the developing and adult mouse.	RARA RARB RARG	2.81e-08	6	40	3	9590554
Pubmed	Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors alpha, beta, and gamma, and retinoid X receptors alpha, beta, and gamma in the mouse testis.	RARA RARB RARG	2.81e-08	6	40	3	9075714
Pubmed	Dissecting the role of retinoic acid receptor isoforms in the CD8 response to infection.	RARA RARB RARG	4.92e-08	7	40	3	24610012
Pubmed	Isotype-restricted corepressor recruitment: a constitutively closed helix 12 conformation in retinoic acid receptors beta and gamma interferes with corepressor recruitment and prevents transcriptional repression.	RARA RARB RARG	4.92e-08	7	40	3	12665583
Pubmed	Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary.	RARA RARB RARG	4.92e-08	7	40	3	28274610
Pubmed	Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha.	RARA RARB RARG	4.92e-08	7	40	3	11493527
Pubmed	Retinoic acid receptors and cellular retinoid binding proteins. III. Their differential transcript distribution during mouse nervous system development.	RARA RARB RARG	4.92e-08	7	40	3	8397079
Pubmed	Role of the retinoic acid receptor beta (RARbeta) during mouse development.	RARA RARB RARG	4.92e-08	7	40	3	9240560
Pubmed	Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions.	RARA RARB RARG	4.92e-08	7	40	3	12360493
Pubmed	Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors.	RARA RARB RARG	4.92e-08	7	40	3	17195188
Pubmed	Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways.	RARA RARB RARG	4.92e-08	7	40	3	10684250
Pubmed	Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases.	RARA RARB RARG	4.92e-08	7	40	3	15635645
Pubmed	Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.	RARA RARB RARG	4.92e-08	7	40	3	8090775
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	NSD1 RARA RARB RARG	7.65e-08	35	40	4	19389355
Pubmed	Retinoic acid receptors exhibit cell-autonomous functions in cranial neural crest cells.	RARA RARB RARG	7.86e-08	8	40	3	19777591
Pubmed	Expression of nuclear retinoic acid receptors during mouse odontogenesis.	RARA RARB RARG	7.86e-08	8	40	3	7988794
Pubmed	Retinoids and adipose tissues: metabolism, cell differentiation and gene expression.	RARA RARB RARG	7.86e-08	8	40	3	10094571
Pubmed	Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.	RARA RARB RARG	7.86e-08	8	40	3	17124491
Pubmed	Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid.	RARA RARB RARG	1.18e-07	9	40	3	8555112
Pubmed	Retinoid signaling determines germ cell fate in mice.	RARA RARB RARG	1.18e-07	9	40	3	16574820
Pubmed	Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.	RARA RARB RARG	1.18e-07	9	40	3	21722948
Pubmed	The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor.	RARA RARB RARG	1.68e-07	10	40	3	17363140
Pubmed	Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter.	RARA RARB RARG	2.31e-07	11	40	3	29093497
Pubmed	Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT.	RARA RARB RARG	2.31e-07	11	40	3	18233958
Pubmed	Close linkage of retinoic acid receptor genes with homeobox- and keratin-encoding genes on paralogous segments of mouse chromosomes 11 and 15.	RARA RARB RARG	3.08e-07	12	40	3	1377062
Pubmed	Correction: RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiation (doi: 10.1242/dev.164822).	RARA RARB RARG	3.08e-07	12	40	3	30166332
Pubmed	Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse.	RARA RARB RARG	3.08e-07	12	40	3	9022057
Pubmed	Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma.	RARA RARB RARG	3.08e-07	12	40	3	8251184
Pubmed	Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.	RARA RARB RARG	3.08e-07	12	40	3	26427057
Pubmed	Isolation and developmental expression of retinoic-acid-induced genes.	RARA RARB RARG	3.08e-07	12	40	3	8314004
Pubmed	RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiation.	RARA RARB RARG	4.00e-07	13	40	3	29986869
Interaction	WWOX interactions	EZR WBP1 VPS37C TMEM171 RARA TMEM92 DAZAP1 ATXN2 PITX2	2.97e-06	627	40	9	int:WWOX
Interaction	YAP1 interactions	NSD1 RNF38 EZR WBP1 JCAD SIN3A RARG TMEM92 TJP1 RBBP6 ZMYM4	6.24e-06	1095	40	11	int:YAP1
Interaction	BICD1 interactions	JCAD PTPN23 SMG7 RAPH1 NCKAP5L TJP1	9.25e-06	250	40	6	int:BICD1
Interaction	NCOA1 interactions	RARA RARB RARG SMG7 RBBP6	9.99e-06	146	40	5	int:NCOA1
Interaction	NCOR2 interactions	SIN3A RARA SGIP1 RARB RARG SMG7	1.26e-05	264	40	6	int:NCOR2
Interaction	ITGB1BP2 interactions	RARA RARB RARG	1.62e-05	25	40	3	int:ITGB1BP2
Interaction	AP2A1 interactions	EZR PTPN23 RARA SGIP1 SMG7 EPN1	2.55e-05	299	40	6	int:AP2A1
Interaction	HACE1 interactions	RARA RARB RARG	2.55e-05	29	40	3	int:HACE1
Interaction	RUNX1 interactions	RNF38 EZR VPS37C SIN3A RARA ZMYM4	3.99e-05	324	40	6	int:RUNX1
Interaction	OCLN interactions	EZR JCAD TMEM171 CPNE8 EPN1 TJP1 TMEM51	5.09e-05	500	40	7	int:OCLN
Interaction	KRTAP7-1 interactions	RNF38 VPS37C PITX2	5.82e-05	38	40	3	int:KRTAP7-1
Interaction	H2AZ1 interactions	NSD1 EZR SIN3A RARG EPN1 ZMYM4	8.45e-05	371	40	6	int:H2AZ1
Interaction	NEDD4 interactions	RNF38 EZR WBP1 TMEM171 IRS2 TMEM92 TMEM51	8.64e-05	544	40	7	int:NEDD4
Interaction	KHDRBS1 interactions	EZR SIN3A RARA KHDRBS3 ATXN2 TJP1	8.71e-05	373	40	6	int:KHDRBS1
Interaction	RARB interactions	RARA RARB RARG	1.04e-04	46	40	3	int:RARB
Interaction	DNMBP interactions	PTPN23 RAPH1 TJP1 SYNE2	1.05e-04	124	40	4	int:DNMBP
Interaction	RXRG interactions	RARA RARB RARG	1.11e-04	47	40	3	int:RXRG
Interaction	WWTR1 interactions	EZR PTPN23 SIN3A SMG7 RAPH1 TJP1	1.71e-04	422	40	6	int:WWTR1
Interaction	CEP135 interactions	JCAD SMG7 NCKAP5L TJP1 ZMYM4	1.93e-04	272	40	5	int:CEP135
Interaction	ARID1A interactions	SIN3A RARA RARB RARG SMG7	2.07e-04	276	40	5	int:ARID1A
Interaction	RHOB interactions	CPNE8 IRS2 SGIP1 RAPH1 EPN1 NCKAP5L TJP1 ASH1L	2.07e-04	840	40	8	int:RHOB
Interaction	RARG interactions	RARA RARB RARG	2.07e-04	58	40	3	int:RARG
Interaction	S100A3 interactions	RARA SGIP1 RARG	2.18e-04	59	40	3	int:S100A3
Interaction	VASP interactions	PTPN23 IRS2 SMG7 RAPH1 TJP1	2.77e-04	294	40	5	int:VASP
Interaction	SSTR2 interactions	SHANK1 SHANK2	2.95e-04	13	40	2	int:SSTR2
Interaction	RXRB interactions	RARA RARB RARG	3.04e-04	66	40	3	int:RXRB
Interaction	RXRA interactions	NSD1 RARA RARB RARG	3.45e-04	169	40	4	int:RXRA
Interaction	SH3D19 interactions	EZR PTPN23 TJP1	3.47e-04	69	40	3	int:SH3D19
Interaction	ZDHHC23 interactions	VPS37C CPNE8 SIN3A	4.26e-04	74	40	3	int:ZDHHC23
Interaction	DZIP3 interactions	RNF38 SIN3A NCKAP5L ATXN2	4.66e-04	183	40	4	int:DZIP3
Interaction	PFN1 interactions	SMG7 DAZAP1 RAPH1 TJP1 ZMYM4 SYNE2	4.66e-04	509	40	6	int:PFN1
Interaction	ENTR1 interactions	EZR PTPN23 SMG7 TJP1	5.16e-04	188	40	4	int:ENTR1
Cytoband	1q22	KHDC4 ASH1L	1.15e-03	57	40	2	1q22
Cytoband	Ensembl 112 genes in cytogenetic band chr1q22	KHDC4 ASH1L	1.77e-03	71	40	2	chr1q22
GeneFamily	Nuclear hormone receptors	RARA RARB RARG	5.84e-05	49	28	3	71
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD1 ASH1L	1.26e-03	34	28	2	487
GeneFamily	PDZ domain containing	SHANK1 SHANK2 TJP1	1.64e-03	152	28	3	1220
GeneFamily	Sterile alpha motif domain containing	SHANK1 SHANK2	8.15e-03	88	28	2	760
GeneFamily	PHD finger proteins	NSD1 ASH1L	8.52e-03	90	28	2	88
GeneFamily	PRD class homeoboxes and pseudogenes	RAX PITX2	8.88e-03	92	28	2	521
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	SMG7 DAZAP1 EPN1 NCKAP5L KHDC4 PPRC1 RBBP6	7.21e-07	338	40	7	M17094
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	EZR RARB RBBP6 SYNE2 ASH1L	1.52e-07	138	40	5	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR RARA RARG TMEM51	1.15e-05	156	40	4	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR TMEM171 SHANK2 FIGNL2	1.34e-05	162	40	4	3a1cbfed5a063131d49e3c1584f62b12660ecb36
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR TMEM171 SHANK2 FIGNL2	1.34e-05	162	40	4	04b3c38bb27fa369a9ac5b60883f8b058abc5180
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARA RARG RAPH1 TMEM51	1.73e-05	173	40	4	807183fc23478da9451906dacd88de4e73112e0d
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARA RARG RAPH1 TMEM51	1.73e-05	173	40	4	2e683ec555dc0036875e0f5674dcc5e93ead205d
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	RARB RARG SHANK2 SYNE2	1.94e-05	178	40	4	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 JCAD TJP1 SYNE2	2.30e-05	186	40	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	E17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	JCAD CPNE8 RAPH1 TJP1	2.35e-05	187	40	4	e9aa0a5a0f8e2593de63e83b56b53ae33e60af49
ToppCell	E17.5-Endothelial-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	JCAD CPNE8 RAPH1 TJP1	2.35e-05	187	40	4	61b8a53f29bb8b33c69f680b8359a1143a23999d
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 SGIP1 NRCAM TJP1	2.40e-05	188	40	4	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	LAMA2 SGIP1 NRCAM TJP1	2.45e-05	189	40	4	d7ed96add29f219183c802895fbff519b627f635
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 IRS2 NCKAP5L TMEM51	2.55e-05	191	40	4	2f733d510a4862565a817f59829d8387d7ea26d9
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 IRS2 NCKAP5L TMEM51	2.55e-05	191	40	4	8691eba35793e4e90f93d50c2145847ee51289f7
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EZR RARB SHANK2 SYNE2	2.77e-05	195	40	4	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	RARA RARG NCKAP5L TMEM51	2.77e-05	195	40	4	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 IRS2 SGIP1 ASH1L	2.77e-05	195	40	4	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EZR SHANK2 TMEM51 SYNE2	2.88e-05	197	40	4	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMA2 TMEM171 RAPH1 TJP1	2.88e-05	197	40	4	2872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	TJP1 RBBP6 SYNE2 ZBTB4	2.94e-05	198	40	4	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	proximal-3-mesenchymal-Pericyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LAMA2 SGIP1 NRCAM TJP1	3.05e-05	200	40	4	98cbd0f4994e645f70c0bc5ebc1c3a3b28c6b67f
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	LAMA2 JCAD CPNE8 SYNE2	3.05e-05	200	40	4	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	LAMA2 SGIP1 NRCAM SYNE2	3.05e-05	200	40	4	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	LAMA2 SGIP1 NRCAM SYNE2	3.05e-05	200	40	4	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	LAMA2 JCAD CPNE8 SYNE2	3.05e-05	200	40	4	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	LAMA2 JCAD CPNE8 SYNE2	3.05e-05	200	40	4	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	proximal-mesenchymal-Pericyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LAMA2 SGIP1 NRCAM TJP1	3.05e-05	200	40	4	03119a979bc912a98e6fc87addcbc25d8ecf2fb0
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	LAMA2 JCAD CPNE8 SYNE2	3.05e-05	200	40	4	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	LAMA2 JCAD CPNE8 SYNE2	3.05e-05	200	40	4	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAMA2 SGIP1 NRCAM SYNE2	3.05e-05	200	40	4	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	LAMA2 JCAD CPNE8 SYNE2	3.05e-05	200	40	4	7136936d05ab344a560cf159684c881063b5430d
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	JCAD RARG KHDRBS3 TJP1	3.05e-05	200	40	4	66f7e8ee63c828f17468e79a4b816346b33e8980
ToppCell	proximal-mesenchymal-Pericyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LAMA2 SGIP1 NRCAM TJP1	3.05e-05	200	40	4	a81fde3d40b8efb3be535aeb2a44cfbdeb17bc8b
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RARB SYNE2 ASH1L	1.74e-04	121	40	3	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Neuronal-Interneuron\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	SHANK1 RNF38 RARA	1.92e-04	125	40	3	eafc39072467e209c9fe3a4fa41cb09507a42e82
ToppCell	COVID-19-kidney-Mito-rich_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JCAD RARB SYNE2	2.97e-04	145	40	3	afed661aef990edb8e7012ab67ace56443520c9f
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR RARA TMEM51	3.54e-04	154	40	3	1e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCell	facs-Brain_Myeloid-Cerebellum\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR RARA TMEM51	3.68e-04	156	40	3	28c4fb4d2c6c47696c3a6722998f9da5a8923323
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM171 SGIP1 NRCAM	3.96e-04	160	40	3	03b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR RARA TMEM51	3.96e-04	160	40	3	1f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell	droplet-Marrow-BM-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARA RARG TMEM51	3.96e-04	160	40	3	822adcf5f9208f305cafffd8ed97f3a061e82b03
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	LAMA2 PTPN23 RARG	4.03e-04	161	40	3	048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell	droplet-Marrow-BM-30m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARA RARG TMEM51	4.11e-04	162	40	3	76e289ad9fd3694f77fd0d19e74c1cb8e87b8094
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM171 RARA TMEM51	4.33e-04	165	40	3	ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RNF38 PPRC1 TMEM51	4.33e-04	165	40	3	94a5211072464fc24592bb107a853ce832e816fe
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SMG7 TJP1 TMEM51	4.49e-04	167	40	3	774f3264318b002d0df5d06d41d645366038d0bf
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SHANK2 TMEM92 NRCAM	4.49e-04	167	40	3	25af48c640e67848594f5902867ba325fc105da4
ToppCell	Bronchial_Biopsy-Immune-T_and_NK\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	LAMA2 JCAD TMEM171	4.56e-04	168	40	3	435b2f238fbb3f50427e8cdecf2220615015153c
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPNE8 ATXN2 ZMYM4	4.64e-04	169	40	3	f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA2 JCAD RARB	4.72e-04	170	40	3	5de2f7d16a05af74ebfb1ca42d0f9c3c3524692d
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell\|E16.5-samps / Age Group, Lineage, Cell class and subclass	EZR TMEM171 SHANK2	4.72e-04	170	40	3	5a64e05c263df915085988d881808221e2c0f2e2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RARB SHANK2 SYNE2	4.72e-04	170	40	3	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|Endothelial_cells / Location, Cell class and cell subclass	EZR IRS2 NRCAM	4.81e-04	171	40	3	dcb6c41980008d0b9eeb54999faff77311554976
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	LAMA2 SGIP1 NRCAM	4.81e-04	171	40	3	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	metastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	RARB NRCAM TJP1	4.89e-04	172	40	3	38d17e769fe8eac8b57b820490d4ddd969243ee7
ToppCell	NS-critical-d_0-4-Epithelial-FOXN4+\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	WBP1 TMEM171 TMEM92	4.89e-04	172	40	3	a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARA TMEM51 SYNE2	4.97e-04	173	40	3	c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LAMA2 KHDC4 PPRC1	4.97e-04	173	40	3	5295ed31648abf8edff214cf67cd4769f20f9e6d
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SHANK1 TMEM171 RARG	5.06e-04	174	40	3	5e6050d20a5b27640f6a200441125b8ceba123c8
ToppCell	droplet-Marrow-BM-30m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARA RARG TMEM51	5.06e-04	174	40	3	118ba2729ecc6aa1bb8548f3cf537b3f9e902ef0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	JCAD RARB KHDRBS3	5.06e-04	174	40	3	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARG RAPH1 TMEM51	5.14e-04	175	40	3	69b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM171 CPNE8 RARB	5.14e-04	175	40	3	c1a8a55af825d5913095f919fa860828df9c273e
ToppCell	droplet-Marrow-nan-18m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARA RARG TMEM51	5.14e-04	175	40	3	510c46bfd250ef83fcad8f6b01efbcca9d71a9a2
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM171 CPNE8 RARB	5.14e-04	175	40	3	78b453e220218c84557f244ef7a760e4a1952761
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARG RAPH1 TMEM51	5.14e-04	175	40	3	4f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCell	droplet-Marrow-nan-24m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARA RARG TMEM51	5.23e-04	176	40	3	eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-2\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBPL2 TMEM171 PITX2	5.31e-04	177	40	3	8f0873d348f37c823294b698043319b6608b678a
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SGIP1 NRCAM TJP1	5.40e-04	178	40	3	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 SYNE2 ASH1L	5.40e-04	178	40	3	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM171 SGIP1 NRCAM	5.40e-04	178	40	3	4df6218b20c2f076c22346d23260964cc0d73e65
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SHANK1 TMEM171 RARG	5.49e-04	179	40	3	bc95c3e7edc5fc6fc913b09f087d221df64c6f48
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPNE8 NRCAM RAPH1	5.49e-04	179	40	3	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 SGIP1 RAX	5.58e-04	180	40	3	f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCell	droplet-Lung-nan-18m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 SGIP1 RAX	5.58e-04	180	40	3	dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD KHDRBS3 TJP1	5.58e-04	180	40	3	544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCell	E18.5-samps-Mesenchymal-Pericyte\|E18.5-samps / Age Group, Lineage, Cell class and subclass	LAMA2 SGIP1 TMEM51	5.58e-04	180	40	3	0b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD TJP1 SYNE2	5.67e-04	181	40	3	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMEM171 RARG SYNE2	5.76e-04	182	40	3	f30e5a21b49f30b82e2b6f1fd2daefd805a40083
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EZR RARB SHANK2	5.76e-04	182	40	3	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD TJP1 SYNE2	5.76e-04	182	40	3	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	COVID-19_Severe-Lymphoid_T/NK-MAIT\|COVID-19_Severe / Disease group, lineage and cell class	TMEM171 RARG SYNE2	5.76e-04	182	40	3	19045db5c726c06ec6e4feb4311633c8164ddb3c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMEM171 RARG SYNE2	5.76e-04	182	40	3	1444cdc4522a70a40d697ccadf54cf26d327ade0
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TMEM171 RARG SYNE2	5.76e-04	182	40	3	cccac9f85825f4e310b86e37ee6320769a670501
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TMEM171 RARG SYNE2	5.76e-04	182	40	3	49eced222e8f90c2b59bcc7d56b62c3e703fcce5
ToppCell	URO-Lymphocyte-T_NK-dnT\|URO / Disease, Lineage and Cell Type	VPS37C RARG SYNE2	5.76e-04	182	40	3	f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SHANK2 NRCAM SYNE2	5.85e-04	183	40	3	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	RBBP6 SYNE2 ASH1L	5.85e-04	183	40	3	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR TMEM171 SHANK2	5.95e-04	184	40	3	10706441e7695212f95689414f31e8082b5eaf0a
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LAMA2 KHDRBS3 FIGNL2	5.95e-04	184	40	3	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR TMEM171 SHANK2	5.95e-04	184	40	3	4bb0976a75126ad2b3deb5d2229f0716fafe200e
ToppCell	COVID-19-Fibroblasts-Pericytes\|COVID-19 / group, cell type (main and fine annotations)	SGIP1 NRCAM TJP1	6.04e-04	185	40	3	4905adaeeffd353e089578e5ea614437dbe794e6
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD IRS2 ASH1L	6.04e-04	185	40	3	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c5-WDR74\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	VPS37C RAPH1 TMEM51	6.04e-04	185	40	3	68edb1bb03ed221d49e583123ca4de14252d7bc5
ToppCell	COPD-Stromal-Pericyte\|World / Disease state, Lineage and Cell class	SGIP1 NRCAM TJP1	6.14e-04	186	40	3	8adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCell	droplet-Kidney-nan-21m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBPL2 TMEM171 PITX2	6.14e-04	186	40	3	393f00ea6b434d4c8854dd8070d176579b71cd3b
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMA2 SGIP1 NRCAM	6.14e-04	186	40	3	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR RARB TMEM51	6.23e-04	187	40	3	5fae538de481367cf6d9a2d52190d77b99f6922c
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR SYNE2 ASH1L	6.23e-04	187	40	3	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	JCAD NRCAM RAPH1	6.23e-04	187	40	3	7e376831a11ee72ed87abcdac631ca46ae29c250
Computational	Genes upregulated in subsets of cells of a given type within various tumors	TJP1 ZMYM4 SYNE2 ASH1L	2.34e-06	50	21	4	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drug	Tazarotene	RARA RARB RARG	2.01e-08	4	40	3	DB00799
Drug	Alitretinoin	RARA RARB RARG	1.00e-07	6	40	3	DB00523
Drug	Adapalene	RARA RARB RARG	1.00e-07	6	40	3	DB00210
Drug	Etretinate	RARA RARB RARG	1.00e-07	6	40	3	DB00926
Drug	Acitretin	RARA RARB RARG	1.75e-07	7	40	3	DB00459
Drug	HX 600	RARA RARB RARG	2.80e-07	8	40	3	ctd:C104181
Drug	4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid	RARA RARB RARG	2.80e-07	8	40	3	ctd:C064545
Drug	Adapalene	RARA RARB RARG	2.80e-07	8	40	3	ctd:D000068816
Drug	TTNN	RARA RARB RARG	2.80e-07	8	40	3	CID000135754
Drug	4-((4-(4-ethylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl)ethynyl)benzoic acid	RARA RARB RARG	2.80e-07	8	40	3	ctd:C121616
Drug	UVI 3003	RARA RARB RARG	8.21e-07	11	40	3	ctd:C525131
Drug	4-hydroxyretinoic acid	RARA RARB RARG	1.09e-06	12	40	3	ctd:C019429
Drug	Cd2665	RARA RARB RARG	1.42e-06	13	40	3	CID000216241
Drug	AC1L1DMQ	RARA RARB RARG	1.80e-06	14	40	3	CID000002418
Drug	Ro 8-8717	RARA RARB	3.01e-06	2	40	2	CID006438148
Drug	4-carboxyphenylretinamide	RARB RARG	3.01e-06	2	40	2	CID006439748
Drug	Tamibarotene	RARA RARB	3.01e-06	2	40	2	DB04942
Drug	HX600	RARA RARB RARG	4.02e-06	18	40	3	CID000128016
Drug	3,4-didehydroretinoic acid	RARA RARB RARG	4.02e-06	18	40	3	CID000447276
Drug	4-(1H-imidazol-1-yl)retinoic acid	RARA RARB RARG	4.02e-06	18	40	3	ctd:C496751
Drug	adapalene	RARA RARB RARG	7.56e-06	22	40	3	CID000060164
Drug	AC1L32JQ	RARA RARB RARG	8.68e-06	23	40	3	CID000133319
Drug	AGN 190299	RARB RARG	9.02e-06	3	40	2	ctd:C090766
Drug	3-((4,6-diphenoxy-1,3,5-triazin-2-yl)amino)benzoic acid	RARB RARG	9.02e-06	3	40	2	ctd:C529372
Drug	AC1L2X6Z	RARA RARB RARG	1.43e-05	27	40	3	CID000130325
Drug	SRI 5898-21	RARA RARB	1.80e-05	4	40	2	CID006439757
Drug	AGN 193109	RARA RARB RARG	1.97e-05	30	40	3	ctd:C096920
Drug	Ro 41-5253	RARA RARB RARG	1.97e-05	30	40	3	ctd:C084904
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	RARA RARG SMG7 PPRC1 RBBP6	2.10e-05	192	40	5	6986_DN
Drug	AGN 193109	RARA RARB RARG	2.18e-05	31	40	3	CID000177238
Drug	Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; HL60; HT_HG-U133A	RARB KHDRBS3 NRCAM TJP1 TMEM51	2.43e-05	198	40	5	3110_UP
Drug	Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	RARA RARG SMG7 TJP1 ASH1L	2.49e-05	199	40	5	6209_DN
Drug	CD367	RARA RARB RARG	2.64e-05	33	40	3	CID000119342
Drug	Cd2366	RARA RARB	3.00e-05	5	40	2	CID006443796
Drug	Ro 41-5253	RARA RARB RARG	3.74e-05	37	40	3	CID005312120
Drug	tazarotene	RARA RARB RARG	4.74e-05	40	40	3	CID000005381
Drug	4-oxoretinoic acid	LAMA2 RARA RARB RARG	4.91e-05	115	40	4	ctd:C002202
Drug	Etretinate-d3	RARA RARB RARG	6.77e-05	45	40	3	CID000003312
Drug	2-naphthoic acid	RARA RARB	8.37e-05	8	40	2	CID000007123
Drug	4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid	RARA RARB RARG	9.87e-05	51	40	3	ctd:C038864
Drug	retinyl methyl ether	RARA RARB	1.08e-04	9	40	2	CID006436634
Drug	HX 630	RARA RARB	1.34e-04	10	40	2	ctd:C422175
Drug	3,5-di-tert-butylchalcone 4'-carboxylic acid	RARB RARG	1.34e-04	10	40	2	ctd:C054189
Drug	CEPC	RARA RARB	1.34e-04	10	40	2	CID000011483
Drug	CK 6	RARA RARB RARG	1.45e-04	58	40	3	CID000447960
Drug	tazarotene	RARB RARG	1.64e-04	11	40	2	ctd:C086827
Drug	AC1L2E0P	NSD1 RARA RARB RARG PPRC1	1.93e-04	307	40	5	CID000019390
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	NSD1 RARA RARG PPRC1	2.27e-04	171	40	4	1000_DN
Drug	tazarotenic acid	RARB RARG	2.32e-04	13	40	2	CID000147525
Drug	Ro 13-6298	RARA RARB	2.32e-04	13	40	2	CID006437076
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 RARA RARG PPRC1	2.32e-04	172	40	4	2330_DN
Drug	retinamide	RARA RARB RARG	2.43e-04	69	40	3	CID005370221
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NSD1 RARA SMG7 NRCAM	2.48e-04	175	40	4	6891_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	NSD1 RARA RARG PPRC1	2.54e-04	176	40	4	981_DN
Drug	9-cis-acitretin	RARA RARB RARG	2.64e-04	71	40	3	CID000041317
Drug	AC1L1JIR	RARA RARB RARG	2.75e-04	72	40	3	CID000005058
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	IRS2 RARG SMG7 RBBP6	2.88e-04	182	40	4	947_DN
Drug	Androgen Antagonists	SHANK1 SHANK2 NRCAM	3.11e-04	75	40	3	ctd:D000726
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	RARA RARG SMG7 RBBP6	3.33e-04	189	40	4	1006_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	RARA RARG PPRC1 RBBP6	3.33e-04	189	40	4	5203_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	RARA RARG PPRC1 RBBP6	3.33e-04	189	40	4	1643_DN
Drug	Griseofulvin	RARA RARB RARG	3.36e-04	77	40	3	ctd:D006118
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	RARA SMG7 RBBP6 TMEM51	3.46e-04	191	40	4	998_DN
Drug	AC1L1KPQ	RARA RARB RARG	3.49e-04	78	40	3	CID000005602
Drug	TAC 101	RARA RARB	3.56e-04	16	40	2	ctd:C112689
Drug	Zardaverine [101975-10-4]; Up 200; 15uM; MCF7; HT_HG-U133A	IRS2 RARA SHANK2 EPN1	3.67e-04	194	40	4	7347_UP
Drug	diclofenac sodium; Down 200; 10uM; MCF7; HG-U133A	IRS2 RARA RARB RARG	3.75e-04	195	40	4	333_DN
Drug	Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; HL60; HT_HG-U133A	RARA SHANK2 NRCAM TMEM51	3.75e-04	195	40	4	3038_UP
Drug	Cyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	RARB RARG SMG7 NRCAM	3.75e-04	195	40	4	3800_UP
Drug	radicicol; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	IRS2 RARA RARG RBBP6	3.75e-04	195	40	4	953_DN
Drug	A-74702	RARA RARB RARG	3.76e-04	80	40	3	CID000452307
Drug	Cotinine (-) [486-56-6]; Up 200; 22.6uM; PC3; HG-U133A	IRS2 SHANK2 SMG7 ATXN2	3.82e-04	196	40	4	1929_UP
Drug	Acemetacin [53164-05-9]; Up 200; 9.6uM; PC3; HT_HG-U133A	IRS2 RARG NRCAM ZMYM4	3.82e-04	196	40	4	6361_UP
Drug	Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A	RARG SMG7 EPN1 ASH1L	3.82e-04	196	40	4	4100_DN
Drug	Viomycin sulfate [37883-00-4]; Down 200; 5.2uM; PC3; HT_HG-U133A	NSD1 JCAD IRS2 RARA	3.82e-04	196	40	4	7278_DN
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; MCF7; HT_HG-U133A	NSD1 IRS2 RARG SMG7	3.82e-04	196	40	4	4948_DN
Drug	Sulfaguanidine [57-67-0]; Up 200; 18.6uM; PC3; HG-U133A	RARA RARG SMG7 KHDRBS3	3.82e-04	196	40	4	1913_UP
Drug	Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; HL60; HT_HG-U133A	LAMA2 SHANK2 SMG7 SYNE2	3.89e-04	197	40	4	2954_UP
Drug	Brinzolamide [138890-62-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A	IRS2 RARA RARB RARG	3.89e-04	197	40	4	5016_UP
Drug	Beclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A	LAMA2 IRS2 SHANK2 EPN1	3.89e-04	197	40	4	4403_UP
Drug	Epiandrosterone [481-29-8]; Up 200; 13.8uM; HL60; HT_HG-U133A	RARA SMG7 EPN1 TMEM51	3.89e-04	197	40	4	2444_UP
Drug	Mebendazole [31431-39-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A	RNF38 RARG PITX2 ASH1L	3.89e-04	197	40	4	2300_DN
Drug	Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	SHANK2 SMG7 NRCAM TMEM51	3.89e-04	197	40	4	1468_DN
Drug	Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A	JCAD IRS2 SHANK2 ZMYM4	3.97e-04	198	40	4	3414_UP
Drug	Ticarcillin sodium [4697-14-7]; Up 200; 9.4uM; HL60; HT_HG-U133A	RARA KHDRBS3 EPN1 TMEM51	3.97e-04	198	40	4	6146_UP
Drug	0179445-0000 [211246-22-9]; Up 200; 1uM; PC3; HT_HG-U133A	SHANK1 RARG SHANK2 EPN1	3.97e-04	198	40	4	4292_UP
Drug	Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A	RARA SHANK2 TMEM51 ASH1L	3.97e-04	198	40	4	6239_DN
Drug	GW0072	RARB PPRC1	4.03e-04	17	40	2	CID000449532
Drug	protoporphyrin IX dimethyl ester	RARA RARB	4.03e-04	17	40	2	CID000194637
Drug	enilconazole	RARA RARG	4.03e-04	17	40	2	ctd:C017435
Drug	Trolox [53188-07-1]; Up 200; 16uM; MCF7; HT_HG-U133A	JCAD IRS2 RARA SHANK2	4.05e-04	199	40	4	2883_UP
Drug	Bumetanide [28395-03-1]; Up 200; 11uM; MCF7; HT_HG-U133A	LAMA2 JCAD RARA EPN1	4.05e-04	199	40	4	5542_UP
Drug	Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A	LAMA2 JCAD RARA EPN1	4.05e-04	199	40	4	4423_UP
Drug	Leucomisine [17946-87-1]; Up 200; 16.2uM; HL60; HT_HG-U133A	RARA RARG SHANK2 NRCAM	4.05e-04	199	40	4	6125_UP
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A	RARA RARG SHANK2 SMG7	4.05e-04	199	40	4	4543_DN
Drug	Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; HL60; HT_HG-U133A	LAMA2 SMG7 NRCAM PITX2	4.05e-04	199	40	4	3079_DN
Drug	Clidinium bromide [3485-62-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A	RARA RARG SHANK2 SMG7	4.12e-04	200	40	4	6837_UP
Drug	CD437	TBPL2 RARA RARB RARG	4.36e-04	203	40	4	CID000135411
Drug	SR11237	RARA RARB	4.52e-04	18	40	2	CID000127019
Drug	tamibarotene	RARA RARB RARG	4.65e-04	86	40	3	CID000108143
Disease	factor VIII measurement, Ischemic stroke	TMEM171 ATXN2 PITX2	2.04e-06	19	39	3	EFO_0004630, HP_0002140
Disease	pain	NSD1 LAMA2 SGIP1 ATXN2 TMEM51	5.89e-06	196	39	5	EFO_0003843
Disease	Ischemic stroke, von Willebrand factor measurement	TMEM171 ATXN2 PITX2	8.46e-06	30	39	3	EFO_0004629, HP_0002140
Disease	Neuralgia-Neuritis, Sciatic Nerve	RARA RARB	1.02e-05	4	39	2	C0751924
Disease	Sciatic Nerve Palsy	RARA RARB	1.02e-05	4	39	2	C0751925
Disease	Lesion of Sciatic Nerve	RARA RARB	1.02e-05	4	39	2	C0154748
Disease	Sciatic Neuritis	RARA RARB	1.02e-05	4	39	2	C0242013
Disease	Sciatic Neuropathy	RARA RARB	1.02e-05	4	39	2	C0149940
Disease	Congenital muscular dystrophy (disorder)	LAMA2 SYNE2	2.54e-05	6	39	2	C0699743
Disease	autism spectrum disorder (implicated_via_orthology)	SHANK1 SHANK2 NRCAM ASH1L	4.84e-05	152	39	4	DOID:0060041 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	LAMA2 RARA RARB RARG DAZAP1 NRCAM RAPH1 SYNE2	6.76e-05	1074	39	8	C0006142
Disease	serum urea measurement	NSD1 TMEM171 TMEM51 ASH1L	1.27e-04	195	39	4	EFO_0009795
Disease	juvenile idiopathic arthritis	LAMA2 NRCAM ATXN2	1.30e-04	74	39	3	EFO_0002609
Disease	Ischemic stroke, tissue plasminogen activator measurement	ATXN2 PITX2	1.77e-04	15	39	2	EFO_0004791, HP_0002140
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	ATXN2 PITX2	2.02e-04	16	39	2	EFO_0004792, HP_0002140
Disease	factor XI measurement, Ischemic stroke	ATXN2 PITX2	2.29e-04	17	39	2	EFO_0004694, HP_0002140
Disease	Intellectual Disability	NSD1 PTPN23 SIN3A SHANK2 ASH1L	2.94e-04	447	39	5	C3714756
Disease	Anophthalmia-microphthalmia syndrome	RAX PITX2	3.52e-04	21	39	2	cv:C5680330
Disease	Autistic Disorder	SHANK1 NSD1 SHANK2 NRCAM	3.86e-04	261	39	4	C0004352
Disease	von Willebrand factor measurement, coronary artery disease	JCAD TMEM171 ATXN2	5.13e-04	118	39	3	EFO_0001645, EFO_0004629
Disease	Ischemic stroke, factor VII measurement	ATXN2 PITX2	6.76e-04	29	39	2	EFO_0004619, HP_0002140
Disease	Mental Retardation, Psychosocial	NSD1 SIN3A SHANK2	8.26e-04	139	39	3	C0025363
Disease	Profound Mental Retardation	NSD1 SIN3A SHANK2	8.26e-04	139	39	3	C0020796
Disease	Mental deficiency	NSD1 SIN3A SHANK2	8.26e-04	139	39	3	C0917816
Disease	unipolar depression	TBPL2 JCAD SGIP1 SHANK2 ZMYM4 SYNE2 ASH1L	9.14e-04	1206	39	7	EFO_0003761
Disease	carbohydrate intake measurement	RARB ATXN2	9.30e-04	34	39	2	EFO_0010811
Disease	urate measurement	NSD1 TMEM171 SIN3A SHANK2 ATXN2 ASH1L	1.06e-03	895	39	6	EFO_0004531
Disease	Craniofacial Abnormalities	SIN3A RAX PITX2	1.15e-03	156	39	3	C0376634
Disease	migraine disorder	NSD1 JCAD TMEM51 ZBTB4	1.24e-03	357	39	4	MONDO_0005277
Disease	spleen volume	ATXN2 TJP1	1.49e-03	43	39	2	EFO_0600047
Disease	blood phosphate measurement	NSD1 RARB ATXN2	1.58e-03	174	39	3	EFO_0010972
Disease	heart failure	SGIP1 ATXN2 PITX2	1.88e-03	185	39	3	EFO_0003144

Protein segments in the cluster

Peptide	Gene	Start	Entry
PTLYPPPPSPSFTTP	ASH1L	1406	Q9NR48
PPPPPPFTSYIVSTP	DAZAP1	256	Q96EP5
ASYIPPSPPTPPVPV	RAPH1	821	Q70E73
YVPPPVPLPPGPSTH	NSD1	2221	Q96L73
IVPSPPSPPPLPRIY	RARA	71	P10276
LVPSPPSPLPPPRVY	RARB	71	P10826
SSPSPPPPPRVYKPC	RARG	76	P13631
PVPPPQPLPTPYTYP	PTPN23	911	Q9H3S7
SPEPPPSPLQVPTYP	NCKAP5L	571	Q9HCH0
PTPTPAPVYDVPNPP	NRCAM	636	Q92823
PVPVSPGVQPLYPIP	ATXN2	971	Q99700
EPPVYVPPPSYRSPP	JCAD	336	Q9P266
PEPVPTPAFPTPTPV	LAMA2	2731	P24043
PATPVFVPVPPPPLY	RBBP6	551	Q7Z6E9
SSPYPPLPPRPSASP	IRS2	1011	Q9Y4H2
SPVPPVPGAPPTYIS	EPN1	536	Q9Y6I3
PALPTGVPPVPTQYP	KHDC4	396	Q7Z7F0
PTGYRPPPPPPTQET	KHDRBS3	251	O75525
PPPPPPVYEPVSYHV	EZR	471	P15311
PAPTPLPAPAPPTAY	FIGNL2	236	A6NMB9
PSGYPCLPPPPTVPL	PPRC1	931	Q5VV67
PSPAPPPYTPPTHVL	CPNE8	546	Q86YQ8
YPPSAHPPTLPPSAP	RNF38	326	Q9H0F5
VPPVPPASSTPYKPP	SYNE2	6476	Q8WXH0
RPGFPPPTYVIPPPV	SMG7	661	Q92540
TPPLPPYASPRSPPV	SIN3A	266	Q96ST3
AVPTPACPYAPPTPP	PITX2	256	Q99697
PAQSLPASYTPPPPP	RAX	266	Q9Y2V3
PSPPPPSPTTYNCPK	SHANK2	896	Q9UPX8
PPPPTTSPPEPPYST	SHANK1	921	Q9Y566
TSPPEPPYSTPPVPS	SHANK1	926	Q9Y566
PTPTEPPPPYSFRPE	TMEM92	131	Q6UXU6
PPPPPPPTYRTVVSS	SGIP1	411	Q9BQI5
PPPSIEPLTPPPQYD	TMEM51	226	Q9NW97
EYPPPPPEPAATPTS	ZBTB4	521	Q9P1Z0
SVIIFPPPPPPYFPE	TMEM171	216	Q8WVE6
PIQATPPPPPLPSQY	TJP1	1421	Q07157
PPYPLPYSPSPSLPV	VPS37C	201	A5D8V6
PPIYPTSPGPIPITL	UHRF1BP1	1331	Q6BDS2
TPPPPYTVAPGRPLT	WBP1	136	Q96G27
TGYTVPPARPPPPLT	ZMYM4	371	Q5VZL5
PRLPSYPPPPPTVGL	TBPL2	16	Q6SJ96