Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribose phosphate diphosphokinase activity	PRPS2 PRPS1L1 PRPS1	8.36e-06	5	190	3	GO:0004749
GeneOntologyMolecularFunction	diphosphotransferase activity	PRPS2 PRPS1L1 PRPS1	1.66e-05	6	190	3	GO:0016778
GeneOntologyMolecularFunction	UDP-glucose:glycoprotein glucosyltransferase activity	UGGT1 UGGT2	9.01e-05	2	190	2	GO:0003980
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DENND4A MYO9B BCR CAVIN4 TBC1D1 THG1L HERC2 ARHGAP21 RALGDS PRR5 ARFGEF1 PREX2 FGD6 NCKAP1L	3.69e-04	507	190	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DENND4A MYO9B BCR CAVIN4 TBC1D1 THG1L HERC2 ARHGAP21 RALGDS PRR5 ARFGEF1 PREX2 FGD6 NCKAP1L	3.69e-04	507	190	14	GO:0030695
GeneOntologyBiologicalProcess	5-phosphoribose 1-diphosphate metabolic process	PRPS2 PRPS1L1 PRPS1	1.48e-05	6	189	3	GO:0046391
GeneOntologyBiologicalProcess	5-phosphoribose 1-diphosphate biosynthetic process	PRPS2 PRPS1L1 PRPS1	1.48e-05	6	189	3	GO:0006015
GeneOntologyCellularComponent	ribose phosphate diphosphokinase complex	PRPS2 PRPS1L1 PRPS1	7.76e-06	5	194	3	GO:0002189
Domain	PRPP_SYNTHASE	PRPS2 PRPS1L1 PRPS1	1.04e-06	3	190	3	PS00114
Domain	PRib_PP_synth_CS	PRPS2 PRPS1L1 PRPS1	1.04e-06	3	190	3	IPR000842
Domain	Pribosyltran_N	PRPS2 PRPS1L1 PRPS1	1.02e-05	5	190	3	PF13793
Domain	Pribosyl_synth	PRPS2 PRPS1L1 PRPS1	1.02e-05	5	190	3	PF14572
Domain	Rib-P_diPkinase	PRPS2 PRPS1L1 PRPS1	1.02e-05	5	190	3	IPR005946
Domain	Pribosyltran_N	PRPS2 PRPS1L1 PRPS1	1.02e-05	5	190	3	IPR029099
Domain	Nck-associated_protein-1	NCKAP1 NCKAP1L	1.03e-04	2	190	2	IPR019137
Domain	Ribosomal_L26	RPL26 RPL26L1	1.03e-04	2	190	2	PF16906
Domain	UDP-g_GGtrans	UGGT1 UGGT2	1.03e-04	2	190	2	IPR009448
Domain	Nckap1	NCKAP1 NCKAP1L	1.03e-04	2	190	2	PF09735
Domain	Ribosomal_L26/L24P_euk/arc	RPL26 RPL26L1	1.03e-04	2	190	2	IPR005756
Domain	UDP-g_GGTase	UGGT1 UGGT2	1.03e-04	2	190	2	PF06427
Domain	Pribosyltran	PRPS2 PRPS1L1 PRPS1	1.61e-04	11	190	3	PF00156
Domain	PRTase-like	PRPS2 PRPS1L1 PRPS1	2.13e-04	12	190	3	IPR029057
Domain	PRibTrfase_dom	PRPS2 PRPS1L1 PRPS1	2.13e-04	12	190	3	IPR000836
Domain	-	PRPS2 PRPS1L1 PRPS1	2.13e-04	12	190	3	3.40.50.2020
Domain	DUF4599	SPATA31A7 SPATA31A3 SPATA31A5	2.13e-04	12	190	3	PF15371
Domain	DUF4599	SPATA31A7 SPATA31A3 SPATA31A5	2.13e-04	12	190	3	IPR027970
Domain	Ribosomal_L24/26_CS	RPL26 RPL26L1	3.07e-04	3	190	2	IPR005825
Domain	RIBOSOMAL_L24	RPL26 RPL26L1	3.07e-04	3	190	2	PS01108
Domain	Rib_L2_dom2	RPL26 HERC2 RPL26L1	7.56e-04	18	190	3	IPR014722
Domain	-	RPL26 HERC2 RPL26L1	7.56e-04	18	190	3	2.30.30.30
Domain	FN3	FNDC5 PHYHIP MDGA2 NEO1 LRFN2 PTPRF FSD1 FSD1L	1.00e-03	199	190	8	PS50853
Domain	AWS	NSD3 NSD1	1.01e-03	5	190	2	SM00570
Domain	AWS	NSD3 NSD1	1.01e-03	5	190	2	PS51215
Domain	AWS_dom	NSD3 NSD1	1.01e-03	5	190	2	IPR006560
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RPL26 DENND4A HIVEP2 CDC42EP4 NCKAP1 EXPH5 CLASP2 BCR NSD3 CEP350 MAST4 KCNQ5 TBC1D1 MAP3K9 FNIP1 PLEC ARHGAP21 MRPS28 CAMSAP3 PRR5 ANKRD26 APC CRTC1 FSD1 CEP112 SH3D19 NUP93 FGD6	1.01e-13	861	197	28	36931259
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	NCKAP1 VPS13C PKD1L1 TSC1 BCR MEN1 CEP350 GRK2 MAST4 TBC1D1 PLEC HERC2 CPLANE1 MGA ARHGAP21 PRRC2B L3MBTL2 CAMSAP3 ANKRD26 APC CRTC1 AP4E1 TGM3 NUP93 PCNT	2.19e-11	853	197	25	28718761
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ZC3H13 UGGT1 MBNL1 CLASP2 MEN1 NF2 KCNJ3 MAP3K9 TSTD2 PLEC CPLANE1 MGA ARHGAP21 DCDC2 PMS2 SMC6 NSD1 APC CRTC1 CCND2 KAT7 MTA1 CNOT6L CEP112 PCNT NCKAP1L	6.37e-10	1084	197	26	11544199
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A7 SPATA31A3 SPATA31A5 SPATA31A1	1.48e-08	6	197	4	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A7 SPATA31A3 SPATA31A5 SPATA31A1	1.48e-08	6	197	4	25930072
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TPRN UGGT1 BMS1 TSC1 PSMD8 CLASP2 NSD3 CEP350 PTPRF NF2 PHLPP1 HERC2 PRRC2B KIF22 GPD2 PMS2 CAMSAP3 RNF213 GTF2E1 CEP72 NUP93 SLC12A7 PCNT	3.49e-08	1049	197	23	27880917
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	PRPS2 DCAF1 DENND4A NCKAP1 MBNL1 PSMD8 CLASP2 BCR TBC1D1 PLEC RSPH10B PRRC2B CUL2 MRPS28 SMC6 CAMSAP3 CRTC1 SOWAHA CNOT6L SMC3 RPL26L1 IPO13 UGGT2 MYL12B FGD6	1.43e-07	1321	197	25	27173435
Pubmed	Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.	PRPS2 PRPS1L1 PRPS1	1.79e-07	3	197	3	1314091
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PRPS2 RPL26 DENND4A UGGT1 TSC1 PSMD8 FER1L6 PRPS1L1 MEN1 C9orf43 PLEC DNAH6 ARHGAP21 PRRC2B ZSWIM5 FBF1 CAMSAP3 ANKRD26 CEP112 RPL26L1 SLC25A13 UGGT2 TUBD1 RPL4 PCNT PRPS1	2.01e-07	1442	197	26	35575683
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DENND4A BCR FREM2 ARHGAP21 PRRC2B CUL2 RALGDS CAMSAP3 APC MORC2 CEMIP SMG8 AACS UGGT2 PARN MICU2 SLC12A7	2.10e-07	650	197	17	38777146
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RPL26 NCKAP1 ZC3H13 UGGT1 BMS1 PLEC HERC2 PRRC2B NSD1 TGM3 UTP4 SLC25A13 PDCD11 PARN NUP93 RPL4 PCNT	2.24e-07	653	197	17	22586326
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	CEP350 PLEC HERC2 MGA RNF213 RPL4 PRPS1	2.64e-07	76	197	7	27542412
Pubmed	Genomic analysis of mouse retinal development.	CDC42EP4 TMEM94 MBNL1 TSC1 SAG NRXN2 TBC1D1 SECISBP2 PLEC PRRC2B RALGDS PMS2 RBPMS SMC6 NSD1 APC ID2 RAX CCND2 WDFY3 PRPS1	3.20e-07	1006	197	21	15226823
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	NSD3 MEN1 HERC2 MGA KIF22 L3MBTL2 NACC1 SMC6 NSD1 MORC2 KAT7 GTF2E1 MTA1 SMC3 UTP4 SNAPC4	4.46e-07	608	197	16	36089195
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CDC42EP4 VPS13C BMS1 CLASP2 CEP350 NEO1 NF2 MGA ARHGAP21 PRRC2B SMC6 ANKRD26 APC ARFGEF1 RNF213 AP4E1 RPL4 PRPS1	5.33e-07	777	197	18	35844135
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	PRPS2 RPL26 RPL35A TPRN MYL9 NF2 SERPINB12 PLEC KIF22 SHC4 TGM3 SMC3 RPL26L1 UTP4 SLC25A13 PDCD11 NUP93 MYL12B RPL4 PRPS1	5.36e-07	949	197	20	36574265
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DCAF1 RPL35A NCKAP1 MYO9B BMS1 TSC1 SERPINB12 DDX60L PLEC HERC2 MGA MRPS28 L3MBTL2 RTF2 KAT7 TGM3 SMG8 SMC3 UTP4 SLC25A13 PDCD11 NUP93 WDFY3 RPL4	8.23e-07	1353	197	24	29467282
Pubmed	A human MAP kinase interactome.	HIVEP2 CDC42EP4 EXPH5 NSD3 CEP350 PLEC HERC2 CPLANE1 MGA RALGDS APC CRTC1 SMC3 SH3D19	8.32e-07	486	197	14	20936779
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	CDC42EP4 TMEM94 EXPH5 TSC1 PLEKHN1 NEO1 PTPRF NF2 ARHGAP21 ANKRD26 ARFGEF1 STXBP6 STON2 SLC12A7 FGD6	1.01e-06	569	197	15	30639242
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TMEM94 VPS13C UGGT1 TSC1 CLASP2 BCR CEP350 NEO1 KANK1 SECISBP2 MGA L3MBTL2 APC SHC4 RNF213 CNOT6L UGGT2	1.10e-06	733	197	17	34672954
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	DCAF1 RPL26 HIVEP2 BMS1 CLASP2 BCR NF2 PHLPP1 PLEC HERC2 PRRC2B CUL2 APC USP37 TGM3 SMC3 SLC25A13 UGGT2 NUP93 MYL12B	1.29e-06	1005	197	20	19615732
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DCAF1 NCKAP1 TMEM94 TSC1 KANK1 LRFN2 TBC1D1 FNIP1 ARHGAP21 PRRC2B ZSWIM5 PCNT	4.08e-06	407	197	12	12693553
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	DCAF1 RPL26 UGGT1 DCST1 CEACAM1 CEP350 HERC2 MRPS28 FBF1 APC CCND2 CEP72 RPL26L1 MYL12B RPL4	4.17e-06	639	197	15	23443559
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MBNL1 BCR CEP350 GRK2 NF2 SECISBP2 PLEC MGA PRRC2B SMC6 ANKRD26 APC MORC2 MTA1 UTP4 MYL12B	4.25e-06	724	197	16	36232890
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIVEP2 MYO9B TMEM94 MED14 CLASP2 BCR NSD3 PTPRF NF2 NLRC5 PLEC HERC2 ARHGAP21 PRRC2B LAD1 NSD1 PDCD11 WDFY3 SNAPC4 PCNT	5.36e-06	1105	197	20	35748872
Pubmed	Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.	PSMD8 SERPINB12 PLEC MGA L3MBTL2 RTF2 RPL26L1 SLC25A13 IPO13	5.42e-06	222	197	9	35941108
Pubmed	Functional proteomics mapping of a human signaling pathway.	EXPH5 TPRN PSMD8 KANK1 MAST4 PTPRF TBC1D1 SECISBP2 PLEC HERC2 MGA CXXC5 PIGQ UBXN11	7.93e-06	591	197	14	15231748
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A7 SPATA31A3 SPATA31A5 SPATA31A1	9.71e-06	24	197	4	32212159
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PRPS2 RPL26 RPL35A EXPH5 ZC3H13 UGGT1 BMS1 NSD3 SERPINB12 PLEC LAD1 TGM3 SMC3 UTP4 SLC25A13 STON2 PDCD11 NUP93 MICU2 MYL12B RPL4	1.04e-05	1257	197	21	36526897
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCKAP1 TSC1 CLASP2 BCR HERC2 MGA UNC79 ARHGAP21 PRRC2B NACC1 CAMSAP3 NSD1 APC SH3D19 STON2 PARN WDFY3 PCNT	1.05e-05	963	197	18	28671696
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	ZC3H13 PLEC DNAH6 RNF213 CEP72 ANKRD36 RPL4 PCNT	1.23e-05	187	197	8	26460568
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	BDP1 TPRN MDGA2 LRFN2 DDX60L NACC1 SYT6 ODAD2 LINC02912 CCND2 GTF2E1 UBXN11 CEP72 STON2 TUBD1 NCKAP1L	1.81e-05	814	197	16	23251661
Pubmed	ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.	TSC1 MEN1 NF2 PMS2 APC	1.83e-05	57	197	5	23788249
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	MEN1 MGA L3MBTL2 NACC1 CXXC5 MTA1 SMC3	2.10e-05	146	197	7	23892456
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ILDR2 RPL26 RPL35A NCKAP1 PHYHIP TSC1 CLASP2 BCR GRK2 NRXN2 ACTL6B PLEC DNAH6 ARHGAP21 PRRC2B GPD2 CAMSAP3 APC STON2 MYL12B RPL4 PRPS1	2.28e-05	1431	197	22	37142655
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	RPL35A BMS1 IKZF1 PLEC SMC6 UTP4 PDCD11 PARN NUP93 PCNT	2.68e-05	340	197	10	29478914
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	DENND4A CLASP2 BCR CEP350 MAST4 FNIP1 ARHGAP21 APC	2.75e-05	209	197	8	36779422
Pubmed	Seventy-five genetic loci influencing the human red blood cell.	DENND4A IKZF1 ACTL6B KIF22 CCND2	2.76e-05	62	197	5	23222517
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	RPL35A HIVEP2 PSMD8 MEN1 MGA L3MBTL2 PRR5 TGM3 SOWAHA MTA1 CEP72 MYL12B	2.85e-05	495	197	12	27705803
Pubmed	Akkermansia muciniphila inhibits tryptophan metabolism via the AhR/β-catenin signaling pathway to counter the progression of colorectal cancer.	AHR APC	3.19e-05	2	197	2	37781044
Pubmed	Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity.	UGGT1 UGGT2	3.19e-05	2	197	2	10694380
Pubmed	KANK1 inhibits cell growth by inducing apoptosis through regulating CXXC5 in human malignant peripheral nerve sheath tumors.	KANK1 CXXC5	3.19e-05	2	197	2	28067315
Pubmed	mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization.	TSC1 CRTC1	3.19e-05	2	197	2	19052232
Pubmed	Metabolomic analysis reveals hepatic metabolite perturbations in citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mice, a model of human citrin deficiency.	GPD2 SLC25A13	3.19e-05	2	197	2	21908222
Pubmed	Cardiac hyporesponsiveness in severe sepsis is associated with nitric oxide-dependent activation of G protein receptor kinase.	GRK2 NOS2	3.19e-05	2	197	2	28526706
Pubmed	Two distinct cDNA sequences encoding the human helix-loop-helix protein Id2.	ID2B ID2	3.19e-05	2	197	2	8224921
Pubmed	Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.	GRK2 GRK3	3.19e-05	2	197	2	10198406
Pubmed	Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model.	GPD2 SLC25A13	3.19e-05	2	197	2	30862943
Pubmed	Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice.	TSC1 CRTC1	3.19e-05	2	197	2	22457330
Pubmed	Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the Apc(Min/+) mouse.	NOS2 APC	3.19e-05	2	197	2	11606502
Pubmed	The merlin tumor suppressor interacts with Ral guanine nucleotide dissociation stimulator and inhibits its activity.	NF2 RALGDS	3.19e-05	2	197	2	16007223
Pubmed	Muscle mTORC1 suppression by IL-6 during cancer cachexia: a role for AMPK.	APC CRTC1	3.19e-05	2	197	2	23531613
Pubmed	G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.	GRK2 GRK3	3.19e-05	2	197	2	11762794
Pubmed	Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2.	UGGT1 UGGT2	3.19e-05	2	197	2	33320095
Pubmed	Citrin/mitochondrial glycerol-3-phosphate dehydrogenase double knock-out mice recapitulate features of human citrin deficiency.	GPD2 SLC25A13	3.19e-05	2	197	2	17591776
Pubmed	A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing.	PMS2 APC	3.19e-05	2	197	2	34489406
Pubmed	Effects of domain composition on catalytic activity of human UDP-glucose:glycoprotein glucosyltransferases.	UGGT1 UGGT2	3.19e-05	2	197	2	27496766
Pubmed	The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis.	NOS2 APC	3.19e-05	2	197	2	16329147
Pubmed	Mechanism for increased hepatic glycerol synthesis in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse: Urine glycerol and glycerol 3-phosphate as potential diagnostic markers of human citrin deficiency.	GPD2 SLC25A13	3.19e-05	2	197	2	25952905
Pubmed	The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis.	NCKAP1 NCKAP1L	3.19e-05	2	197	2	7643388
Pubmed	Oral aversion to dietary sugar, ethanol and glycerol correlates with alterations in specific hepatic metabolites in a mouse model of human citrin deficiency.	GPD2 SLC25A13	3.19e-05	2	197	2	28259708
Pubmed	Cloning of GRK2 cDNA from S49 murine lymphoma cells.	GRK2 GRK3	3.19e-05	2	197	2	8638670
Pubmed	Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival.	NOS2 APC	3.19e-05	2	197	2	17096347
Pubmed	Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.	GRK2 GRK3	3.19e-05	2	197	2	33060647
Pubmed	[Increased activity of PRPP synthetase].	PRPS2 PRPS1	3.19e-05	2	197	2	18409517
Pubmed	Id2 deletion attenuates Apc-deficient ileal tumor formation.	APC ID2	3.19e-05	2	197	2	26163528
Pubmed	G protein--coupled receptor kinases.	GRK2 GRK3	3.19e-05	2	197	2	8035170
Pubmed	Effect of exposure to cigarette smoke on carotid artery intimal thickening: the role of inducible NO synthase.	AHR NOS2	3.19e-05	2	197	2	15271786
Pubmed	NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesion molecule 1 in non-small cell lung cancer.	CEACAM1 NLRC5	3.19e-05	2	197	2	36694434
Pubmed	PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness.	PRPS2 PRPS1	3.19e-05	2	197	2	33493137
Pubmed	Effects of supplementation on food intake, body weight and hepatic metabolites in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse model of human citrin deficiency.	GPD2 SLC25A13	3.19e-05	2	197	2	22921887
Pubmed	Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1.	DCAF1 NF2	3.19e-05	2	197	2	24706749
Pubmed	Interstitial deletion of 3p22.3p22.2 encompassing ARPP21 and CLASP2 is a potential pathogenic factor for a syndromic form of intellectual disability: a co-morbidity model with additional copy number variations in a large family.	ARPP21 CLASP2	3.19e-05	2	197	2	24127197
Pubmed	Progesterone regulates the expression and activity of two mouse isoforms of the glycoprotein folding sensor UDP-Glc: glycoprotein glucosyltransferase (UGGT).	UGGT1 UGGT2	3.19e-05	2	197	2	24140206
Pubmed	Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging.	KL APC	3.19e-05	2	197	2	32771388
Pubmed	Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31.	FSD1 FSD1L	3.19e-05	2	197	2	11267680
Pubmed	Tuberous sclerosis complex 1-mechanistic target of rapamycin complex 1 signaling determines brown-to-white adipocyte phenotypic switch.	TSC1 CRTC1	3.19e-05	2	197	2	25213336
Pubmed	Tissue-differential expression of two distinct genes for phosphoribosyl pyrophosphate synthetase and existence of the testis-specific transcript.	PRPS2 PRPS1	3.19e-05	2	197	2	2537655
Pubmed	The noncatalytic portion of human UDP-glucose: glycoprotein glucosyltransferase I confers UDP-glucose binding and transferase function to the catalytic domain.	UGGT1 UGGT2	3.19e-05	2	197	2	12913004
Pubmed	Both isoforms of human UDP-glucose:glycoprotein glucosyltransferase are enzymatically active.	UGGT1 UGGT2	3.19e-05	2	197	2	24415556
Pubmed	Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production.	NOS2 APC	3.19e-05	2	197	2	11731407
Pubmed	Enhanced intestinal adenomatous polyp formation in Pms2-/-;Min mice.	PMS2 APC	3.19e-05	2	197	2	9515784
Pubmed	Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.	TSC1 APC ID2 CCND2	3.59e-05	33	197	4	27416896
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	RPL26 TPRN ZC3H13 PLEC ARHGAP21 KIF22 CAMSAP3 APC PDCD11 RPL4	4.44e-05	361	197	10	30344098
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RPL35A NCKAP1 BMS1 MED14 CLASP2 NSD3 MEN1 HERC2 KIF22 CAMSAP3 CXXC5 NSD1 APC CRTC1 MORC2 MTA1 CNOT6L UTP4 SLC25A13 PDCD11 PARN MICU2	4.47e-05	1497	197	22	31527615
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	PRPS2 MBNL1 HERC2 KIF22 CUL2 MRPS28 RTF2 RNF213 USP37 MORC2 STON2 PARN MICU2	4.52e-05	604	197	13	38803224
Pubmed	Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminences.	IKZF1 ZSWIM5 SOWAHA	4.91e-05	13	197	3	18799682
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	MED14 MGA L3MBTL2 NACC1 CAMSAP3 CXXC5 MTA1	4.96e-05	167	197	7	20362541
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DENND4A NCKAP1 CLASP2 NF2 TBC1D1 NACC1 FBF1 ANKRD26 APC SMC3 CEP72	5.29e-05	446	197	11	24255178
Pubmed	Lysine acetylation targets protein complexes and co-regulates major cellular functions.	DENND4A TSC1 TBC1D1 RNF213	6.34e-05	38	197	4	19608861
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	NCKAP1 UGGT1 MBNL1 BPNT1 SERPINB12 SMC6 RNF213 TGM3 SMC3	6.46e-05	304	197	9	32235678
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	NCKAP1 TMEM94 BCR MYL9 MAP3K9 DDX60L PLEC CPLANE1 ARHGAP21 PIGQ KAT7 TGM3 STON2 PARN ANKRD36 MYL12B	6.82e-05	910	197	16	36736316
Pubmed	Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis.	MYO9B ARFGEF1 NCKAP1L	7.75e-05	15	197	3	16417406
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	ZC3H13 BMS1 CLASP2 SERPINB12 PLEC MGA PRRC2B L3MBTL2 CAMSAP3 SMC3 RPL4 PRPS1	7.96e-05	551	197	12	34728620
Pubmed	Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.	TMEM94 BMS1 KANK1 PDCD11	8.58e-05	41	197	4	8724849
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	MED14 NSD3 MEN1 CEP350 MSL3 KIF22 PMS2 SMC6 ANKRD26 MORC2 KAT7 CEP72 PCNT	8.75e-05	645	197	13	25281560
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	TMEM94 CLASP2 NF2 HERC2 PRRC2B SYT6 CAMSAP3 APC MORC2 PREX2 RPL4	9.24e-05	475	197	11	31040226
Pubmed	Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.	GRK2 GRK3	9.54e-05	3	197	2	10754297
Pubmed	The NSD family of protein methyltransferases in human cancer.	NSD3 NSD1	9.54e-05	3	197	2	25942451
Pubmed	Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes.	SAG GRK3	9.54e-05	3	197	2	7695743
Interaction	YWHAH interactions	DENND4A HIVEP2 CDC42EP4 NCKAP1 EXPH5 ZC3H13 TSC1 CLASP2 BCR NSD3 CEP350 KANK1 MAST4 KCNQ5 TBC1D1 MAP3K9 FNIP1 PLEC ARHGAP21 MRPS28 CAMSAP3 PRR5 ANKRD26 APC CRTC1 FSD1 CEP112 SH3D19 FGD6 PCNT	2.46e-07	1102	194	30	int:YWHAH
Interaction	YWHAQ interactions	DENND4A ZBTB38 HIVEP2 NCKAP1 EXPH5 ZC3H13 FNDC5 TSC1 CLASP2 BCR CEP350 KANK1 MAST4 KCNQ5 TBC1D1 MAP3K9 PLEC UNC79 NOS2 ARHGAP21 CUL2 CAMSAP3 PRR5 ANKRD26 APC CRTC1 CEP112 SH3D19 MYL12B FGD6	3.35e-07	1118	194	30	int:YWHAQ
Interaction	MAPRE3 interactions	MYO9B IKZF1 CLASP2 BCR CEP350 MAST4 SECISBP2 ARHGAP21 DCDC2 CAMSAP3 APC SH3D19 PCNT	3.77e-07	230	194	13	int:MAPRE3
Interaction	SYNE3 interactions	EXPH5 VPS13C UGGT1 TSC1 CEP350 KCNQ5 SECISBP2 PLEC ARHGAP21 PRRC2B FBF1 CAMSAP3 ANKRD26 APC CEP72 UGGT2 PCNT	1.50e-06	444	194	17	int:SYNE3
Interaction	YWHAZ interactions	BDP1 DENND4A HIVEP2 NCKAP1 EXPH5 FNDC5 TSC1 CLASP2 BCR KANK1 MAST4 KCNQ5 TBC1D1 SERPINB12 MAP3K9 PLEC HERC2 NOS2 ARHGAP21 CUL2 MRPS28 CAMSAP3 PRR5 ANKRD26 APC CRTC1 CEP112 SH3D19 WDFY3 FGD6 PCNT	3.44e-06	1319	194	31	int:YWHAZ
Interaction	SFN interactions	RPL26 DENND4A EXPH5 CLASP2 BCR CEP350 MAST4 KCNQ5 PLEC ARHGAP21 LAD1 CAMSAP3 PRR5 ANKRD26 APC KAT7 CEP112 SH3D19 NUP93 FGD6 RPL4	3.53e-06	692	194	21	int:SFN
Interaction	TRIM52 interactions	MYO9B EXPH5 CEP350 AHR MGA CUL2 L3MBTL2 SNAPC4 PCNT	5.74e-06	133	194	9	int:TRIM52
Interaction	TRIM36 interactions	CLASP2 CEP350 MAST4 SECISBP2 ARHGAP21 DCDC2 CAMSAP3 APC FSD1	1.10e-05	144	194	9	int:TRIM36
Interaction	ATOH1 interactions	CEP350 PLEC HERC2 MGA RNF213 RPL4 PRPS1	1.21e-05	80	194	7	int:ATOH1
Interaction	CEP135 interactions	BCR CEP350 HERC2 ARHGAP21 PRRC2B FBF1 CAMSAP3 ANKRD26 APC CEP72 CEP112 PCNT	1.37e-05	272	194	12	int:CEP135
Interaction	YWHAG interactions	RPL26 DENND4A HIVEP2 NCKAP1 EXPH5 ZC3H13 FNDC5 TSC1 CLASP2 BCR CEP350 KANK1 MAST4 KCNQ5 TBC1D1 MAP3K9 FNIP1 NOS2 ARHGAP21 CAMSAP3 PRR5 ANKRD26 APC CRTC1 USP37 CEP112 SH3D19 FGD6	2.53e-05	1248	194	28	int:YWHAG
Interaction	YWHAE interactions	PRPS2 DCAF1 DENND4A HIVEP2 NCKAP1 EXPH5 FNDC5 TSC1 CLASP2 BCR KANK1 MAST4 KCNQ5 TBC1D1 MAP3K9 MGA NOS2 ARHGAP21 CAMSAP3 PRR5 ANKRD26 APC CRTC1 CEP112 SH3D19 FGD6 RPL4 PRPS1	2.83e-05	1256	194	28	int:YWHAE
Interaction	NIN interactions	CLASP2 MEN1 CEP350 HERC2 CPLANE1 MGA ARHGAP21 L3MBTL2 CAMSAP3 ANKRD26 APC NUP93 PCNT	4.74e-05	359	194	13	int:NIN
GeneFamily	UDP-glucose glycoprotein glucosyltransferases	UGGT1 UGGT2	4.52e-05	2	122	2	440
GeneFamily	L ribosomal proteins	RPL26 RPL35A RPL26L1 RPL4	3.86e-04	51	122	4	729
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHN1 BCR GRK2 GRK3 PHLPP1 ARHGAP21 FGD6	4.99e-04	206	122	7	682
GeneFamily	Fibronectin type III domain containing	FNDC5 NEO1 LRFN2 PTPRF FSD1 FSD1L	7.59e-04	160	122	6	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PDGFRL MDGA2 NEO1 LRFN2 PTPRF ALPK2	7.85e-04	161	122	6	593
GeneFamily	Structural maintenance of chromosomes proteins\|Cohesin complex	SMC6 SMC3	9.28e-04	7	122	2	761
GeneFamily	Zinc fingers SWIM-type\|Mitogen-activated protein kinase kinase kinases	ZSWIM3 ZSWIM5	1.58e-03	9	122	2	90
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ARMCX6 APC ODAD2	3.04e-03	43	122	3	409
GeneFamily	Myosin light chains\|EF-hand domain containing	MYL9 MYL12B	3.90e-03	14	122	2	657
Coexpression	HALLMARK_MITOTIC_SPINDLE	CDC42EP4 MYO9B TSC1 BCR KIF22 APC ARFGEF1 SMC3 CEP72 TUBD1 FGD6 PCNT	3.70e-08	199	196	12	M5893
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	BDP1 ZBTB38 KANK1 MAST4 DCDC2 RBPMS ANKRD26 RNF213 WDFY3 ALPK2	8.98e-07	176	196	10	M39223
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	BDP1 RPL26 DENND4A RPL35A ZBTB38 HIVEP2 CCNDBP1 MYO9B VPS13C MBNL1 IKZF1 CEP350 GRK2 TBC1D1 AHR NLRC5 SECISBP2 PRRC2B RALGDS NSD1 ID2 RNF213 IDS CCND2 CNOT6L SMC3 MYL12B RPL4 NCKAP1L	2.29e-06	1492	196	29	M40023
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	BDP1 ZBTB38 ARPP21 FNDC5 MDGA2 NDST3 MAST4 GRK3 NRXN2 MAP3K9 ACTL6B UNC79 PRRC2B RALGDS SYT6 APC ARFGEF1 SHC4 IDS CPNE5 CEMIP CNOT6L PDIK1L ANKRD36	2.98e-06	1106	196	24	M39071
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	RPL35A CDC42EP4 EXPH5 PHYHIP BRINP1 NDRG2 CEACAM1 BPNT1 MAST4 TBC1D1 MSL3 MAP3K9 PLEC KIF22 RBPMS PRR5 ID2 KCTD14 WDFY3 SNAPC4	1.73e-05	909	196	20	M41018
Coexpression	GSE17721_CTRL_VS_POLYIC_6H_BMDC_DN	CLASP2 BRINP1 CEP350 NOS2 RALGDS MRPS28 IDS UGGT2 ALPK2	2.01e-05	199	196	9	M3716
Coexpression	GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_DN	BCR RTF2 ID2 PCDHA12 TMEM87B SH3D19 KCTD14 SLC12A7 RPL4	2.09e-05	200	196	9	M6360
Coexpression	GRESHOCK_CANCER_COPY_NUMBER_UP	TSC1 IKZF1 BCR NSD3 MEN1 NF2 PMS2 NSD1 APC RNF213 CCND2	3.43e-05	323	196	11	M9150
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	ILDR2 ZC3H13 TSC1 NSD3 MAST4 FNIP1 PLEC CPLANE1 PMS2 PELI1 KAT7 MECR PDIK1L	1.41e-06	275	192	13	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000	ZC3H13 TSC1 NSD3 MAST4 CPLANE1 PMS2 ANKRD26 PELI1 CNOT6L MECR PDIK1L	6.76e-06	225	192	11	gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000	ILDR2 IRX5 TSC1 THG1L FNIP1 CPLANE1 ANKRD26 RNF213 PELI1 MECR KCTD14	9.41e-06	233	192	11	gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000	ILDR2 ZC3H13 TSC1 MAST4 PLEC CPLANE1 CNOT6L MECR WDFY3	9.79e-06	151	192	9	gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500	MED14 CLASP2 NF2 APC PELI1 IDS CCND2	1.63e-05	89	192	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000	MED14 CLASP2 CEP350 NF2 CPLANE1 APC PELI1 IDS CCND2 TGM3	2.15e-05	209	192	10	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000	ILDR2 ZC3H13 TSC1 NSD3 MAST4 PLEC CPLANE1 CNOT6L MECR WDFY3	2.24e-05	210	192	10	gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#1_top-relative-expression-ranked_1000	MED14 CEP350 NF2 TBC1D1 HERC2 CPLANE1 APC PELI1 CCND2	2.90e-05	173	192	9	gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k1
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	ILDR2 IRX5 ZC3H13 FNDC5 TSC1 IKZF1 NSD3 MAST4 FNIP1 PLEC CPLANE1 MGA RNF213 CNOT6L MECR PDIK1L KCTD14 SERPINB1 UGGT2 WDFY3	3.70e-05	795	192	20	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_500	ILDR2 ZC3H13 TSC1 MAST4 FNIP1 CPLANE1 MECR	3.72e-05	101	192	7	gudmap_developingGonad_e14.5_ ovary_500_k1
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	ILDR2 ZC3H13 TSC1 NDRG2 NSD3 MAST4 FNIP1 PLEC CPLANE1 MGA UTY DCDC2 PELI1 CCND2 KAT7 CNOT6L MECR KCTD14 SERPINB1 WDFY3	3.97e-05	799	192	20	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000	ILDR2 ZC3H13 TSC1 NSD3 MAST4 FNIP1 CPLANE1 ANKRD26 PREX2 CNOT6L MECR WDFY3	4.02e-05	323	192	12	gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000	ZC3H13 TSC1 NSD3 MAST4 PLEC CPLANE1 CNOT6L MECR PDIK1L WDFY3	4.85e-05	230	192	10	gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000	MED14 CEP350 NF2 CPLANE1 SMC6 CXXC5 NSD1 APC PELI1 CCND2 MECR PDIK1L	6.40e-05	339	192	12	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	ILDR2 IRX5 ZC3H13 TSC1 NSD3 MAST4 THG1L FNIP1 CPLANE1 MGA PMS2 SMC6 ANKRD26 RNF213 PELI1 CNOT6L MECR PDIK1L KCTD14	8.35e-05	776	192	19	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	ILDR2 IRX5 ZC3H13 FNDC5 TSC1 NSD3 MAST4 FNIP1 PLEC CPLANE1 MGA ZSWIM5 RNF213 PELI1 CNOT6L MECR KCTD14 UGGT2 WDFY3	8.64e-05	778	192	19	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000	MED14 CEP350 KL KANK1 NF2 TBC1D1 SECISBP2 MGA DCDC2 PMS2 ZSWIM5 CXXC5 NSD1 APC PELI1 IDS GTF2E1 STXBP6 SLCO1A2	1.14e-04	795	192	19	gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#3_top-relative-expression-ranked_500	MED14 TBC1D1 CPLANE1 DCDC2 APC PELI1 CCND2	1.24e-04	122	192	7	gudmap_developingLowerUrinaryTract_e15.5_Urothelium_500_k3
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	ILDR2 ZC3H13 TSC1 NSD3 MAST4 FNIP1 PLEC CPLANE1 MGA UTY DCDC2 PMS2 PELI1 KAT7 CNOT6L MECR PDIK1L KCTD14 WDFY3	1.26e-04	801	192	19	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	MED14 CLASP2 CEP350 NF2 HERC2 CPLANE1 NSD1 APC PELI1 IDS CCND2 KCTD14	1.42e-04	369	192	12	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500	FNDC5 MED14 NEO1 MYL9 ARHGAP21 RNF213 TGM3 KCTD14	1.50e-04	168	192	8	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_500
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000	BDP1 MED14 CEP350 KANK1 CPLANE1 PMS2 CXXC5 APC PELI1 IDS STXBP6 TMEM87B	1.65e-04	375	192	12	gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	MED14 CEP350 KANK1 NF2 SECISBP2 MGA PMS2 CXXC5 NSD1 APC PELI1 STXBP6	1.82e-04	379	192	12	gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	BDP1 ILDR2 IKZF1 FREM2 NRXN2 PHLPP1 ZSWIM5 SMC6 CAMSAP3 CXXC5 ANKRD26 SMC3 STON2 FGD6	1.85e-04	498	192	14	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000	ILDR2 IRX5 ZC3H13 TSC1 MAST4 THG1L FNIP1 PLEC CPLANE1 MGA CAMSAP3 RNF213 IDS CNOT6L MECR KCTD14 SERPINB1 WDFY3	2.28e-04	770	192	18	gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_1000	ILDR2 TSC1 FNIP1 CPLANE1 MECR KCTD14	2.52e-04	97	192	6	gudmap_developingGonad_e18.5_epididymis_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	BDP1 ILDR2 MED14 MDGA2 IKZF1 FREM2 NRXN2 PHLPP1 ARHGAP21 ZSWIM5 SMC6 CAMSAP3 CXXC5 ANKRD26 FSD1L SMC3 SLCO1A2 SLC25A13 STON2 FGD6 PCNT	2.54e-04	989	192	21	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500	ILDR2 ZC3H13 MAST4 CPLANE1 MECR	3.05e-04	65	192	5	gudmap_developingGonad_P2_ovary_500_k2
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	ILDR2 ZC3H13 TSC1 NDRG2 NSD3 MAST4 GRK3 FNIP1 PLEC CPLANE1 MGA UTY PELI1 KAT7 CNOT6L MECR SERPINB1 WDFY3	3.11e-04	790	192	18	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_500	ILDR2 ZC3H13 NSD3 MAST4 FNIP1	3.52e-04	67	192	5	gudmap_developingGonad_e18.5_epididymis_500_k3
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_1000	MED14 CLASP2 CEP350 CPLANE1 PELI1 IDS GSDMC CCND2	5.02e-04	201	192	8	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000	CLASP2 NSD3 CEP350 NF2 CPLANE1 PRRC2B APC PELI1 IDS CCND2	5.72e-04	312	192	10	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C UGGT1 GRK3 PTPRF FNIP1 MGA UTY GPD2 NSD1 ARFGEF1	1.69e-08	195	196	10	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB38 VPS13C NDRG2 CEP350 KCNJ3 ARHGAP21 NSD1 STXBP6 CEP112	9.11e-08	176	196	9	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IRX5 FREM2 KANK1 KCNJ3 DNAH6 RBPMS SLCO1A2 WDFY3 ALPK2	1.46e-07	186	196	9	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	DENND4A MBNL1 CLASP2 UTY ARFGEF1 RNF213 IDS CNOT6L ANKRD36	1.91e-07	192	196	9	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C UGGT1 GRK3 PTPRF FNIP1 MGA UTY GPD2 ARFGEF1	2.18e-07	195	196	9	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	VPS13C ZC3H13 NSD3 CEP350 SECISBP2 SMC6 ARFGEF1 SMC3 ANKRD36	2.59e-07	199	196	9	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C9orf43 TBC1D1 NOS2 DCDC2 SOWAHA STON2 WDFY3 ALPK2	1.22e-06	177	196	8	14fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	RPL26 ARPP21 NDST3 NRXN2 MAP3K9 UNC79 FSD1L RPL4	3.03e-06	200	196	8	5b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	ARPP21 HIVEP2 EXPH5 KCNQ5 KCNJ3 ID2 TGM3	6.82e-06	159	196	7	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CEACAM1 GRK3 RBPMS SMC6 ID2 TGM3 MYL12B	9.78e-06	168	196	7	d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CEACAM1 GRK3 RBPMS SMC6 ID2 TGM3 MYL12B	9.78e-06	168	196	7	f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	DENND4A MBNL1 IKZF1 NLRC5 RNF213 CNOT6L ANKRD36	1.10e-05	171	196	7	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells-B-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARPP21 IKZF1 SAG KCNQ5 SMC6 PRR5 NCKAP1L	1.23e-05	174	196	7	9eb3504f9340517ef5d056503044fbdb9ffeb714
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CEACAM1 KCNQ5 SERPINB12 LAD1 TGM3 SOWAHA SERPINB1	1.23e-05	174	196	7	e8440eea7c81864defa57c89e9b569ad8033e5c5
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CEACAM1 KCNQ5 SERPINB12 LAD1 TGM3 SOWAHA SERPINB1	1.23e-05	174	196	7	97d4a40b536a67fa52f055eab26106d041bf3220
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal-Basal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CEACAM1 KCNQ5 SERPINB12 LAD1 TGM3 SOWAHA SERPINB1	1.23e-05	174	196	7	f9f399244c7d12caf8118ec3117d477a39e35c3b
ToppCell	LPS-antiTNF-Lymphocytic_B\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARPP21 IKZF1 SAG KCNQ5 SMC6 PRR5 NCKAP1L	1.23e-05	174	196	7	cc493654ea3517bc6a145c7f787f304929636f86
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARPP21 IKZF1 SAG KCNQ5 SMC6 PRR5 NCKAP1L	1.23e-05	174	196	7	b4c2d1c029fcd0d4926aa79a5b789c713919dcf3
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRL QRICH2 CEACAM1 GRK3 DNAH6 RBPMS SMG8	1.27e-05	175	196	7	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	ARPP21 BCR NDRG2 PHLPP1 ANKRD26 SLCO1A2 WDFY3	1.37e-05	177	196	7	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ILDR2 IRX5 EXPH5 FREM2 PTPRF DCDC2 STON2	1.70e-05	183	196	7	c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND4A BCR DNAH6 UTY TAS1R3 CEP72 STON2	1.70e-05	183	196	7	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	IRX5 EXPH5 FREM2 KANK1 PTPRF MAP3K9 DCDC2	1.89e-05	186	196	7	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXPH5 FNDC5 PHYHIP NDRG2 NDST3 NRXN2 UNC79	1.96e-05	187	196	7	ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	IRX5 PDGFRL EXPH5 FREM2 MAP3K9 DCDC2 CAMSAP3	1.96e-05	187	196	7	c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCell	control\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RPL26 RPL35A NSD3 GRK2 GRK3 RTF2 RPL4	2.02e-05	188	196	7	4688de289d60b76245827dc1f71927bdc01b7fb9
ToppCell	MS-CD8-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	BPNT1 PRR5 USP37 FSD1L RSPH3 NUP93 SNAPC4	2.02e-05	188	196	7	2f0e2c7d79ee2d69a5d908c0247dc950c056c30a
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDC42EP4 BCR MYL9 KCNQ5 TBC1D1 CXXC5 CCND2	2.09e-05	189	196	7	26cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IRX5 KANK1 KCNJ3 DNAH6 RBPMS SLCO1A2 WDFY3	2.09e-05	189	196	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Control-PLT_3\|World / Disease Group and Platelet Clusters	EXPH5 NDRG2 MYL9 ARMCX6 SECISBP2 IDS CPNE5	2.09e-05	189	196	7	f65c261fe25479e900d5ed1a0d25a9dec302a57b
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	IRX5 EXPH5 FREM2 PTPRF MAP3K9 DCDC2 STON2	2.17e-05	190	196	7	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRL FNDC5 NDRG2 MYL9 KCNJ3 CEP112 SH3D19	2.17e-05	190	196	7	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDC42EP4 BCR MYL9 KCNQ5 TBC1D1 CXXC5 CCND2	2.17e-05	190	196	7	2ab604d35456beba71c25511e0f819000e6642d2
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	IRX5 PDGFRL EXPH5 FREM2 MAP3K9 DCDC2 CAMSAP3	2.32e-05	192	196	7	8898332387e5d746feb346ce1dabd6b2218fc6e5
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	NCKAP1 EXPH5 MAST4 PTPRF DNAH6 RBPMS ODAD2	2.32e-05	192	196	7	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	IRX5 EXPH5 FREM2 PTPRF MAP3K9 DCDC2 LAD1	2.32e-05	192	196	7	b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	IRX5 EXPH5 FREM2 PTPRF MAP3K9 DCDC2 LAD1	2.40e-05	193	196	7	ab78fb1603ea6f720ba2d30148fe65dccf271fe1
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EXPH5 FREM2 KANK1 MAST4 PTPRF DCDC2 RBPMS	2.40e-05	193	196	7	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IRX5 FREM2 KCNJ3 RBPMS SLCO1A2 WDFY3 ALPK2	2.48e-05	194	196	7	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	BDP1 ARPP21 ZC3H13 NSD3 FNIP1 SMC3 RPL4	2.48e-05	194	196	7	4903a0d6e36599bcb83b179462e5b949df9eb685
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	IRX5 EXPH5 FREM2 PTPRF MAP3K9 DCDC2 LAD1	2.56e-05	195	196	7	98dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	IRX5 PDGFRL EXPH5 FREM2 PTPRF MAP3K9 DCDC2	2.56e-05	195	196	7	ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRPS2 EXPH5 KL KCNJ3 DCDC2 CPNE5 PIGQ	2.56e-05	195	196	7	3f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EXPH5 FER1L6 FREM2 AHR NOS2 GSDMC STXBP6	2.64e-05	196	196	7	b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EXPH5 FER1L6 FREM2 AHR NOS2 GSDMC STXBP6	2.64e-05	196	196	7	c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCell	15-Trachea-Epithelial-Submucosal_gland\|Trachea / Age, Tissue, Lineage and Cell class	RPL26 RPL35A NDRG2 CEACAM1 ID2 SLCO1A2 KCTD14	2.64e-05	196	196	7	e49aa77c8306237c35c625cde1f03e64c06ffc70
ToppCell	TCGA-Skin-Metastatic-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	DCAF1 DENND4A ZBTB38 VPS13C USP37 SMC3 NCKAP1L	2.82e-05	198	196	7	af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NCKAP1 EXPH5 NDRG2 PTPRF CPLANE1 RBPMS SH3D19	2.82e-05	198	196	7	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	TCGA-Skin-Metastatic\|TCGA-Skin / Sample_Type by Project: Shred V9	DCAF1 DENND4A ZBTB38 VPS13C USP37 SMC3 NCKAP1L	2.82e-05	198	196	7	ad39cce004867f083f8da1954e0cf5a263815184
ToppCell	Caecum-T_cell-Th17\|T_cell / Region, Cell class and subclass	RPL26 NEO1 AHR PRR5 ID2 FSD1 RPL4	2.82e-05	198	196	7	c675878bec307c10326cb85fd398b30029d73522
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	EXPH5 VPS13C ZC3H13 CEP350 SECISBP2 ANKRD26 SMC3	2.82e-05	198	196	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	DCAF1 DENND4A ZBTB38 VPS13C USP37 SMC3 NCKAP1L	2.82e-05	198	196	7	62cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell	ILEUM-non-inflamed-(6)_ILC-(6)_ILC3\|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CEACAM1 NEO1 MAST4 AHR PRR5 ID2 RPL4	2.91e-05	199	196	7	ba144739f65560207303c0143e8de1e86922bebb
ToppCell	severe-Myeloid-CD14_Monocytes_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RPL26 RPL35A GRK3 AHR ID2 UBXN11 RPL4	2.91e-05	199	196	7	ce07b7c1edfc6e2136dafcf041361b66a52271d3
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	ZC3H13 NSD3 MYL9 SMC6 ANKRD26 IDS SMC3	2.91e-05	199	196	7	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	PRPS2 VPS13C ZC3H13 CEP350 ANKRD26 SMC3 ANKRD36	2.91e-05	199	196	7	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	Sigmoid-T_cell-Th17\|T_cell / Region, Cell class and subclass	RPL26 RPL35A NEO1 PRR5 ID2 FSD1 RPL4	2.91e-05	199	196	7	622f2ae4b1850b25f723a0385da49147dfec8285
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	PTPRF CUL2 DCDC2 NACC1 LAD1 NSD1 FGD6	3.01e-05	200	196	7	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	BDP1 MDGA2 KCNQ5 KCNJ3 UNC79 IDS ANKRD36	3.01e-05	200	196	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	NCKAP1 GRK3 PTPRF NRXN2 PRRC2B RALGDS CAMSAP3	3.01e-05	200	196	7	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	DCST1 QRICH2 NLRC5 SPATA22 RAX	4.36e-05	88	196	5	2075743c7c0b6d74e80464a6bc776206d744d502
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	DCST1 QRICH2 NLRC5 SPATA22 RAX	4.36e-05	88	196	5	a49319bc97188550e08248973e10c626124c3917
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	DCST1 QRICH2 NLRC5 SPATA22 RAX	4.36e-05	88	196	5	14b11249a2b3fa327622897fe74630c2697ea47e
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Striatum / BrainAtlas - Mouse McCarroll V32	ARPP21 PHYHIP KCNQ5 PCDHA12 CPNE5 SOWAHA	4.63e-05	146	196	6	7b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	CCDC168 LRFN2 ID2 SHC4 CNOT6L TRBV13	4.81e-05	147	196	6	743767abdb3b5ecad870b617f515b037ce280818
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRL SAG LRFN2 DCDC2 ODAD2 ALPK2	5.18e-05	149	196	6	cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRL SAG LRFN2 DCDC2 ODAD2 ALPK2	5.18e-05	149	196	6	24a7538b54b2a5291503c7493fefed4e45e8d710
ToppCell	COVID-19_Mild\|World / 5 Neutrophil clusters in COVID-19 patients	CCDC168 NSD3 RSPH10B2 SAG DDX60L RTF2	5.79e-05	152	196	6	2ff0980dfd8d430cca14649151d856edef115720
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	DENND4A HIVEP2 UTY RNF213 CNOT6L ANKRD36	6.69e-05	156	196	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO9B IKZF1 BCR CAVIN4 KCNQ5 NCKAP1L	6.93e-05	157	196	6	d12f343454202da86a06d0369f8ffe5662cd091b
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PHYHIP RSPH10B2 DNAH6 DCDC2 ANKRD26 CEP112	6.93e-05	157	196	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	EXPH5 CCDC168 SAG NRXN2 RBPMS RPL4	7.43e-05	159	196	6	b3c52908cd24bbf851fac69db3850fc7f53c2092
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRPS2 BDP1 PRR5 UBXN11 KCTD14 PARN	7.96e-05	161	196	6	249c2b97cc25de5053f5048ee354615df49b2081
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	ARPP21 NDRG2 PHLPP1 PLEC CARD14 SLCO1A2	7.96e-05	161	196	6	347edb0de10850b7d16c40945751033289289c9b
ToppCell	mild_COVID-19_(asymptomatic)-B_cell\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	FNDC5 QRICH2 MYL9 SMC6 CEP112 SH3D19	8.82e-05	164	196	6	e4d43af7eb04d55328791b554bdf3a7ce6818027
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	UNC79 RALGDS SHC4 RAX SMG8 SLCO1A2	9.74e-05	167	196	6	e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B-B_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARPP21 IKZF1 SAG KCNQ5 SMC6 NCKAP1L	1.01e-04	168	196	6	063d0368d656962b335154c230bdcd9236e7c9ad
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 PRR5 RNF213 CPNE5 CCND2 ANKRD36	1.01e-04	168	196	6	f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCell	droplet-Lung-LUNG-30m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCR PTPRF NRXN2 PRR5 CXXC5 AACS	1.01e-04	168	196	6	e156297a7515e785a9e79a9676700bd3a9d92b98
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B-B_cells-B-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARPP21 IKZF1 SAG KCNQ5 SMC6 NCKAP1L	1.01e-04	168	196	6	eeb381b62c7ba263af96de1194ed59e57b6ca3ae
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCR PTPRF NRXN2 PRR5 CXXC5 AACS	1.01e-04	168	196	6	32e0bc0873baa13027241063283ef26d2aab56f5
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42EP4 CUL2 MORC2 CRAT AP4E1 PDIK1L	1.01e-04	168	196	6	b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARPP21 IKZF1 SAG KCNQ5 SMC6 NCKAP1L	1.01e-04	168	196	6	a7c4251d8a83bc30196a444028a35c17c24dc291
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C FNDC5 FREM2 CPLANE1 PRRC2B DCDC2	1.01e-04	168	196	6	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	COPD-Lymphoid-ILC_B\|World / Disease state, Lineage and Cell class	ILDR2 DENND4A KCNQ5 PRR5 ID2 CNOT6L	1.04e-04	169	196	6	01987c00e0e398eb734613a55e71b4a2b1f0bb21
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ILDR2 CAVIN4 KL KCNJ3 UNC79 LAD1	1.04e-04	169	196	6	96a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PTPRF NRXN2 ARHGAP21 LAD1 AGBL3 ALPK2	1.07e-04	170	196	6	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLEC GPD2 ARFGEF1 MORC2 PIGQ RSPH3	1.07e-04	170	196	6	09bcbc7eb3b1d35cf03f01ce2f2fe37373382dd4
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL35A FNDC5 QRICH2 LAD1 ID2 KCTD14	1.18e-04	173	196	6	b6aed736d8480e3a6a5718aabd2fb79b1b75fa48
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	BDP1 DENND4A CLASP2 GRK3 SMC6 CXXC5	1.18e-04	173	196	6	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	EXPH5 MED14 CUL2 LAD1 CNOT6L STXBP6	1.18e-04	173	196	6	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 UGGT1 FNDC5 CEP350 CPNE5 UGGT2	1.22e-04	174	196	6	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	droplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 CEACAM1 GRK3 SMC6 ID2 TGM3	1.26e-04	175	196	6	c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF1 CEACAM1 GRK3 SMC6 ID2 TGM3	1.26e-04	175	196	6	61fbd8f685d3daad46449e4c0386a38886496566
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRK3 TBC1D1 MAP3K9 PHLPP1 RBPMS ARFGEF1	1.26e-04	175	196	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	facs-Skin-Anagen-24m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 PHYHIP NDRG2 NEO1 SYT6 ID2	1.26e-04	175	196	6	5552ff1e13f931c8cd7780726c90b5609497a648
ToppCell	Severe_COVID-19-Myeloid-Neutrophil\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CEACAM1 DDX60L RALGDS RNF213 PELI1 TGM3	1.34e-04	177	196	6	a6fae376f1beb1df423484d9b1bd1d954ca117af
ToppCell	Control\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ILDR2 ZBTB38 FNDC5 UTY RBPMS STXBP6	1.34e-04	177	196	6	b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MDGA2 NDRG2 NRXN2 SHC4 PCDHA12 TGM3	1.34e-04	177	196	6	d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Activated_DCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	CEP350 GRK3 NRXN2 LAD1 ID2 ALPK2	1.34e-04	177	196	6	370aee11a6dc2c6f4366a13c3171f37bc5b32d65
Drug	Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A	EXPH5 MBNL1 NSD3 PTPRF NF2 KCNJ3 RALGDS APC IDS CRAT WDFY3 FGD6	1.19e-07	197	192	12	3338_DN
Drug	Nimodipine [66085-59-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A	NCKAP1 VPS13C NSD3 NF2 C1orf105 CARD14 CUL2 MORC2 CRAT CEP112	5.91e-06	193	192	10	5421_UP
Drug	Etofylline [519-37-9]; Down 200; 17.8uM; MCF7; HT_HG-U133A	IKZF1 NDRG2 NSD3 GRK3 NF2 KCNJ3 ANKRD26 CRTC1 CEMIP MTA1	7.40e-06	198	192	10	2256_DN
Drug	penicillin	PRPS1L1 MEN1 NRXN2 PLEC FSD1 RPL4	7.61e-06	56	192	6	CID000002349
Drug	Ethamivan [304-84-7]; Down 200; 18uM; MCF7; HT_HG-U133A	MYO9B EXPH5 MED14 GRK3 NF2 MSL3 GPD2 NSD1 APC UGGT2	7.74e-06	199	192	10	7021_DN
Drug	methyl iodoacetate	PRPS2 PRPS1L1 PRPS1	1.16e-05	6	192	3	CID006429536
Drug	APP-MP	PRPS2 PRPS1L1 PRPS1	1.16e-05	6	192	3	CID003081102
Drug	pyrimidine-5-nucleotide	PRPS2 PRPS1L1 PRPS1	1.16e-05	6	192	3	CID000440040
Drug	D -Adonose	PRPS2 PRPS1L1 LAD1 CRAT PRPS1	3.76e-05	45	192	5	CID000079021
Drug	Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A	HIVEP2 CEP350 GRK2 GRK3 MSL3 PLEC ID2 UGGT2 FGD6	4.33e-05	195	192	9	5307_DN
Drug	Evoxine [522-11-2]; Down 200; 11.6uM; HL60; HT_HG-U133A	CDC42EP4 MYO9B BCR NDRG2 RALGDS PRR5 ID2 IDS WDFY3	4.51e-05	196	192	9	2186_DN
Drug	Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	MYO9B NEO1 NF2 KCNJ3 MSL3 PLEC MTA1 PDCD11 WDFY3	4.51e-05	196	192	9	7356_DN
Drug	(-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; MCF7; HT_HG-U133A	NDRG2 MSL3 UTY RBPMS NSD1 APC ARFGEF1 UGGT2 SNAPC4	4.51e-05	196	192	9	7027_DN
Drug	Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; HL60; HG-U133A	NDRG2 NSD3 CEP350 GRK3 PRRC2B LAD1 IDS PDCD11 SNAPC4	4.51e-05	196	192	9	1379_UP
Drug	Clemastine fumarate [14976-57-9]; Down 200; 8.6uM; HL60; HT_HG-U133A	CDC42EP4 GRK2 NF2 C1orf105 UTY PRR5 IDS PREX2 WDFY3	4.69e-05	197	192	9	2412_DN
Drug	sodium 4-phenylbutyrate; Up 200; 1000uM; MCF7; HG-U133A	NCKAP1 VPS13C MED14 CLASP2 NDRG2 GRK3 ANKRD26 CRTC1 MYL12B	4.69e-05	197	192	9	407_UP
Drug	Pirenperone [ 75444-65-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	MYO9B IKZF1 GRK3 NF2 CUL2 PRR5 ANKRD26 APC AP4E1	4.69e-05	197	192	9	5274_DN
Drug	thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	KANK1 MAST4 NF2 KCNJ3 C1orf105 PLEC CUL2 AP4E1 CEP72	4.69e-05	197	192	9	5227_DN
Drug	Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A	MYO9B ZC3H13 GRK2 MAST4 GPD2 APC PREX2 CEP112 SNAPC4	4.88e-05	198	192	9	2895_DN
Drug	Josamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A	HIVEP2 MYO9B NDRG2 MAST4 NF2 KCNJ3 SECISBP2 UTY SNAPC4	4.88e-05	198	192	9	1534_DN
Drug	Dicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A	HIVEP2 MYO9B MBNL1 KANK1 PHLPP1 PRRC2B RBPMS CRAT SLC12A7	4.88e-05	198	192	9	3423_DN
Drug	(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; HL60; HT_HG-U133A	SAG NOS2 APC CRTC1 FSD1 IDS CRAT PREX2 MTA1	4.88e-05	198	192	9	2197_UP
Drug	Ethamsylate [2624-44-4]; Down 200; 15.2uM; PC3; HT_HG-U133A	MED14 PTPRF NF2 ANKRD26 IDS MORC2 MTA1 CEP112 TUBD1	4.88e-05	198	192	9	4576_DN
Drug	Repaglinide [135062-02-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A	MED14 KANK1 NF2 MAP3K9 APC FSD1 CRAT MTA1 STXBP6	5.07e-05	199	192	9	3558_DN
Drug	Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; PC3; HT_HG-U133A	DENND4A MYL9 C1orf105 SECISBP2 UTY ANKRD26 MTA1 STXBP6 KCTD14	5.07e-05	199	192	9	5788_DN
Drug	Leucomisine [17946-87-1]; Up 200; 16.2uM; PC3; HT_HG-U133A	MED14 MAST4 MSL3 MAP3K9 SECISBP2 PRRC2B PREX2 CEMIP SNAPC4	5.07e-05	199	192	9	7125_UP
Drug	Trazodone hydrochloride [25332-39-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	CLASP2 KCNJ3 ANKRD26 ARFGEF1 FSD1 IDS CRAT CEP72 SNAPC4	5.07e-05	199	192	9	7452_DN
Drug	Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	MYO9B NSD3 NF2 MAP3K9 PLEC UTY PRR5 ID2 SNAPC4	5.07e-05	199	192	9	6826_DN
Drug	allulose 6-phosphate	PRPS2 PRPS1L1 GRK2 GRK3 GPD2 PMS2 APC PRPS1	7.22e-05	162	192	8	CID000000603
Disease	Sotos syndrome 1 (implicated_via_orthology)	NSD3 NSD1	1.22e-04	3	189	2	DOID:0112103 (implicated_via_orthology)
Disease	Turcot syndrome (disorder)	PMS2 APC	4.03e-04	5	189	2	C0265325
Disease	autism spectrum disorder (implicated_via_orthology)	TSC1 BRINP1 NDST3 LRFN2 NRXN2 WDFY3	4.56e-04	152	189	6	DOID:0060041 (implicated_via_orthology)
Disease	Aplasia Cutis Congenita	BMS1 PLEC	6.02e-04	6	189	2	C0282160
Disease	Colorectal Carcinoma	PDGFRL BRINP1 NDST3 KL KCNQ5 RALGDS PMS2 APC ARFGEF1 PREX2 CCND2 SLCO1A2 PRPS1	6.33e-04	702	189	13	C0009402
Disease	Intellectual Disability	HIVEP2 TMEM94 KCNQ5 NRXN2 MSL3 ACTL6B RALGDS NSD1 APC AP4E1	6.54e-04	447	189	10	C3714756
Disease	sexual dimorphism measurement	ZBTB38 HIVEP2 MYO9B DCST1 PRPS1L1 C1orf105 NLRC5 FNIP1 PLEC MGA CXXC5 NSD1 APC GSDMC CCND2 PARN NUP93	8.00e-04	1106	189	17	EFO_0021796
Disease	epidermolysis bullosa simplex (is_implicated_in)	EXPH5 PLEC	8.39e-04	7	189	2	DOID:4644 (is_implicated_in)
Disease	squamous cell carcinoma	LRFN2 AHR HERC2 TGM3	9.12e-04	67	189	4	EFO_0000707
Disease	Vasogenic Brain Edema	MYL9 NOS2	1.11e-03	8	189	2	C0750969
Disease	Cytotoxic Brain Edema	MYL9 NOS2	1.11e-03	8	189	2	C0750970
Disease	Cytotoxic Cerebral Edema	MYL9 NOS2	1.11e-03	8	189	2	C0472388
Disease	Vasogenic Cerebral Edema	MYL9 NOS2	1.11e-03	8	189	2	C0472387
Disease	blindness (implicated_via_orthology)	RPL26 RPL26L1	1.11e-03	8	189	2	DOID:1432 (implicated_via_orthology)
Disease	Brain Edema	MYL9 NOS2	1.11e-03	8	189	2	C1527311
Disease	Cerebral Edema	MYL9 NOS2	1.11e-03	8	189	2	C0006114
Disease	colorectal cancer (is_implicated_in)	PDGFRL IKZF1 NF2 APC PELI1	1.12e-03	121	189	5	DOID:9256 (is_implicated_in)
Disease	body weight	ZBTB38 HIVEP2 VPS13C MBNL1 MDGA2 BRINP1 LRFN2 MAST4 KCNQ5 TBC1D1 FNIP1 MGA UNC79 CXXC5 CRTC1 CPNE5 CCND2 CEP112	1.30e-03	1261	189	18	EFO_0004338
Disease	HEPATOCELLULAR CARCINOMA	PDGFRL APC	1.43e-03	9	189	2	114550
Disease	Silicosis	AHR NOS2	1.43e-03	9	189	2	C0037116
Disease	Lynch Syndrome	PMS2 APC	1.43e-03	9	189	2	C4552100
Disease	Adult Hepatocellular Carcinoma	PDGFRL TSC1	1.43e-03	9	189	2	C0279607
Disease	Hepatocellular carcinoma	PDGFRL APC	1.43e-03	9	189	2	cv:C2239176
Disease	Nonsyndromic Deafness	BDP1 TPRN DCDC2 CEMIP	1.85e-03	81	189	4	C3711374
Disease	Cardiomegaly	FNDC5 GRK2 AHR CCND2	1.93e-03	82	189	4	C0018800
Disease	Cardiac Hypertrophy	FNDC5 GRK2 AHR CCND2	1.93e-03	82	189	4	C1383860
Disease	cataract	PKD1L1 KCNQ5 HERC2 STXBP6 PCNT	2.19e-03	141	189	5	MONDO_0005129
Disease	Pathological accumulation of air in tissues	KL NOS2	2.58e-03	12	189	2	C0013990
Disease	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	IKZF1 MGA	2.58e-03	12	189	2	C0023485
Disease	Congenital Heart Defects	IRX5 TMEM94 AHR	2.82e-03	44	189	3	C0018798
Disease	potassium measurement	AHR AP4E1 NUP93	3.01e-03	45	189	3	EFO_0009283
Disease	esophageal adenocarcinoma, Barrett's esophagus, sex interaction measurement	CRTC1 CEP72	3.04e-03	13	189	2	EFO_0000280, EFO_0000478, EFO_0008343
Disease	neutrophil count, basophil count	IKZF1 RBPMS PCDHA12 PREX2 STXBP6 SLC12A7	3.31e-03	224	189	6	EFO_0004833, EFO_0005090
Disease	Adenocarcinoma of large intestine	PDGFRL GRK2 PMS2 APC	3.42e-03	96	189	4	C1319315
Disease	caffeine measurement	AHR CRTC1	4.06e-03	15	189	2	EFO_0021177
Disease	Myopia	IRX5 KCNQ5	4.06e-03	15	189	2	C0027092
Disease	Medulloblastoma	PMS2 L3MBTL2 APC	4.06e-03	50	189	3	C0025149
Disease	Hypermetropia	ZBTB38 IRX5 KCNQ5 ARHGAP21	4.40e-03	103	189	4	HP_0000540
Disease	sodium measurement	ARPP21 BRINP1 MEN1 AHR	4.40e-03	103	189	4	EFO_0009282
Disease	cystatin C measurement	HIVEP2 DCST1 AHR FNIP1 NSD1 USP37 CEMIP TGM3	4.55e-03	402	189	8	EFO_0004617
Disease	Uveal Melanoma	BRINP1 KCNJ3 HERC2	4.79e-03	53	189	3	EFO_1000616
Disease	glycochenodeoxycholate measurement	GRK2 CEMIP	5.21e-03	17	189	2	EFO_0010490
Disease	Moyamoya Disease	RNF213 PCNT	5.21e-03	17	189	2	C0026654
Disease	Vascular Diseases	MYL9 AHR	5.21e-03	17	189	2	C0042373
Disease	Necrosis	BCR AHR NOS2	5.31e-03	55	189	3	C0027540
Disease	FEV/FEC ratio	HIVEP2 VPS13C BRINP1 FREM2 KANK1 MYL9 KCNQ5 THG1L MGA MRPS28 NSD1 CRTC1 KAT7 CEP72 UGGT2 FGD6	5.78e-03	1228	189	16	EFO_0004713
Disease	syndrome (implicated_via_orthology)	NSD3 NSD1	5.84e-03	18	189	2	DOID:225 (implicated_via_orthology)
Disease	neutrophil percentage of leukocytes	DENND4A ZBTB38 SIGLEC5 IKZF1 TBC1D1 NLRC5 RBPMS STXBP6 TMEM87B SNAPC4	6.19e-03	610	189	10	EFO_0007990
Disease	lymphocyte count	ZBTB38 EXPH5 MBNL1 SIGLEC5 IKZF1 BCR SAG NRXN2 TBC1D1 PHLPP1 NLRC5 DDX60L PLEC RBPMS NSD1 PREX2 CCND2 TUBD1	6.28e-03	1464	189	18	EFO_0004587
Disease	hepatocellular carcinoma (is_implicated_in)	PDGFRL NF2 APC CCND2 SMC3	6.32e-03	181	189	5	DOID:684 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RKRNTKLPFMFTTGE	AHR	396	P35869
LSKDSLNPSSLLAAM	AHR	446	P35869
VPSSAQMTRRKFQKA	BDP1	1671	A6H8Y1
LMLSKNCPDKFSFSA	AGBL3	491	Q8NEM8
AMEKSKATPAARASK	GRK3	16	P35626
NSDEFKSFMKRLPSN	BRINP1	306	O60477
PDSKKNTQMDRFRAA	AACS	21	Q86V21
VKFNSREFSLKRMPS	BCR	1031	P11274
NSAFLKKMPKLETSL	ALPK2	1751	Q86TB3
KLIASNSTMERKFSP	ACTL6B	376	O94805
VFRSLCKLSMKPLSD	ARFGEF1	426	Q9Y6D6
SPTLFNASSNDMKLK	GSDMC	266	Q9BYG8
NASSNDMKLKPELFL	GSDMC	271	Q9BYG8
MTPKFSLRKSSSFHD	CEP112	231	Q8N8E3
LKPFSLMKASSRFKA	CRAT	16	P43155
LTLKEADPSSKAAMR	ANKRD36	521	A6QL64
FMSDKPLHLAVSLNK	SAG	201	P10523
ELKKTMALFPHSSAS	CEP72	626	Q9P209
PSLAKLMTASQQSRK	ANKRD26	276	Q9UPS8
MSICSSLARKFPKLT	BPNT1	56	O95861
KMASSRVTLFSDSKP	BMS1	386	Q14692
SLLMKKAALPTFDSG	BMS1	566	Q14692
NAAPSKEAFKMRSLR	CAVIN4	261	Q5BKX8
SDRKRFTQIPAKTMS	CAMSAP3	1206	Q9P1Y5
TSNLRMKIIKNDFPS	CEMIP	1011	Q8WUJ3
MLAKSASDLKFPLIS	ARMCX6	231	Q7L4S7
DSDSSNRNLKPAMTK	ARPP21	366	Q9UBL0
AMEKSKATPAARASK	GRK2	16	P25098
VKMSESQAALPSALK	AP4E1	1056	Q9UPM8
QPSMRTELSFSEKKD	ATP1A1-AS1	66	Q5TC04
MNSKDRRLSPATENK	NUP93	356	Q8N1F7
IQRMNSSFSVKPFEK	DENND4A	1146	Q7Z401
KAMKLFDASRTDPTV	NDST3	66	O95803
PQTLRLEFAKANTKM	RBPMS	91	Q93062
PSSKLRDAFSAQMVK	NSD1	1026	Q96L73
DMVNSLAVSRPSKKA	QRICH2	1236	Q9H0J4
DALAKDPKMLRSQSQ	IRX5	451	P78411
RLLDTKLMASTQPFK	PARN	321	O95453
MGLKAAQKTLFPLRS	MEN1	1	O00255
MFLASKLKETSPLTA	CCND2	106	P30279
QPLDLSKALSSMHAK	NOS2	716	P35228
KRSPSLFLCFTKLMT	RSPH10B	511	P0C881
KRSPSLFLCFTKLMT	RSPH10B2	511	B2RC85
AKQKLGFSSSDPDRM	DCAF1	281	Q9Y4B6
AKEAKRSNSNKTMDP	KAT7	586	O95251
LMLSNRLPFSAAKSL	LRRC37A3	1336	O60309
RSASMKLPDNTVKLG	LAD1	391	O00515
SQFRKESRSQSMKEP	LRRD1	16	A4D1F6
SKSRALEHFPMLQKD	GPD2	196	P43304
LPDNMLSTSRKDKSS	MGA	486	Q8IWI9
KTKSKAAPSRLFNMD	L3MBTL2	516	Q969R5
RPAVCNDLSIMSKFK	HERC2	1521	O95714
MAPAFRLSLKAKVSD	FSD1	126	Q9BTV5
AFRLSLKPKVSDNMT	FSD1L	161	Q9BXM9
SQKLSFKERVRMASP	KCNQ5	416	Q9NR82
LPKADSFNLSLSDMS	FREM2	1026	Q5SZK8
LKNLSPDSLSSSKDM	DDX60L	1076	Q5H9U9
TKKRPQRATSNVFAM	MYL9	11	P24844
SASQKLSPLQKLSSM	KIF22	421	Q14807
KRRQQDTSASMPKLF	MSL3	371	Q8N5Y2
KNMFSNLPKLVASRD	NRXN2	1046	Q9P2S2
IRSNFSKPDLMASLL	NCKAP1L	881	P55160
NDPKALTSKDMRFCL	KANK1	1101	Q14678
AAMSKASRKFPAKDV	EXPH5	1596	Q8NEV8
RLASNVAKRKSSMPQ	IKZF1	266	Q13422
SALAASALPALVMSK	RPL4	126	P36578
LSRPTSSQKKMAAEL	PCNT	3026	O95613
LAAAMAVDKSNPTSK	CXXC5	121	Q7LFL8
KMKFFLPNTDLDSRN	NLRC5	31	Q86WI3
KPDQMAALFKRLSSV	NCKAP1	886	Q9Y2A7
IPDKMVSFRLSNKTA	MDGA2	226	Q7Z553
AITPKMLANFLASRK	OR5AS1	76	Q8N127
ASRMSFSSLKRKQPK	NF2	6	P35240
MFKTDALKCRVALSP	MED14	1241	O60244
SFPISKKQLSAMNSD	MORC2	926	Q9Y6X9
KDTFRLFLSSMPSNT	DNAH6	3626	Q9C0G6
SQMFPSSKARTKSLL	FBF1	31	Q8TES7
MDKAKASPLRLSFDR	CARD14	776	Q9BXL6
SNFMRSKKKSLNLPL	CPLANE1	1046	Q9H799
PRDNKAAALLMLTKN	CCNDBP1	166	O95273
FKNQSLPSSERMKLS	CEACAM1	361	P13688
MATSNNPRKFSEKIA	CRTC1	1	Q6UUV9
TAPLRAMFKDLLSSK	DCST1	166	Q5T197
MAPTLFQKLFSKRTG	FNIP1	1	Q8TF40
LEKNRPDSVISSKMF	C9orf43	246	Q8TAL5
MKAFSPVRSIRKNSL	ID2B	1	Q14602
QSRARFNPSISMIKK	CUL2	706	Q13617
LRDSALFVKNAMSLP	CDC42EP4	106	Q9H3Q1
KTTLSTAKELNMPFS	CEP350	1656	Q5VT06
GTSKFATLEMNPKRA	RALGDS	536	Q12967
AAAMTQSAVKSLKRP	MBNL1	266	Q9NR56
ARELSPSSLKMNKSY	MAST4	1856	O15021
FLSQDKMLLPKSSAL	KL	481	Q9UEF7
MKEATTNAPFRLNKK	SERPINB1	176	P30740
ALEASMKPFISSKQI	MECR	356	Q9BV79
IQLLEKMKTSASPFF	IDS	206	P22304
TPKTTRNLKQFSDMK	CCDC168	1686	Q8NDH2
FKDLFSMKPDQSNVR	SLC12A7	1001	Q9Y666
DSFMQLLAQALKRKP	IPO13	791	O94829
LMTLPQKRKSFQSKS	PKD1L1	2736	Q8TDX9
DKSTMRRPFGQKASS	DCDC2	226	Q9UHG0
QASPTMDKRKSLINS	MAP3K9	531	P80192
CRNLLDKDMFSKSDP	CPNE5	31	Q9HCH3
ASLKEPMDQKRYASS	PTPRF	1226	P10586
KTDLMAFSPSLQLSR	PCDHA12	766	Q9UN75
FNTLAFPSMKRKDVV	PELI1	286	Q96FA3
MKFNPFVTSDRSKNR	RPL26L1	1	Q9UNX3
TKKRPQRATSNVFAM	MYL12B	11	O14950
KESALKALNSDMPLY	SMG8	876	Q8ND04
LEMNLNSFPRAAKSA	FER1L6	1711	Q2WGJ9
KGSPKNVESFASMLR	MRPS28	71	Q9Y2Q9
REKKTNLAPKSTAMN	RTF2	236	Q9BY42
SAMPKKDARTLLARF	GTF2E1	166	P29083
FRGNMADKLKDPSTL	SYT6	111	Q5T7P8
SLKRVSKMPAFLRSA	UTP4	426	Q969X6
IMFTKESKPSKNRSL	UTY	661	O14607
SGMVRAKFRSNLPAK	RPL35A	81	P18077
KTFMPKQRSLQSLEA	SMC3	751	Q9UQE7
KPSLKGNREDSARMS	PLEKHN1	21	Q494U1
KLPFNRSSSDMDLQK	SH3D19	361	Q5HYK7
SKTFLMRDGKNTLPC	SPATA22	281	Q8NHS9
SKLDPTQTSFLKMAD	NDRG2	276	Q9UN36
RLKFMSSPSLSDLGK	PRR5	6	P85299
TFLREKSPKFSENMS	ODAD2	296	Q5T2S8
LFKTPREAEKMASKN	FNDC5	121	Q8NAU1
MKAFSPVRSVRKNSL	ID2	1	Q02363
LLSRKPNRKTNTSFM	PDIK1L	131	Q8N165
FSTRKAENPAQLMRK	PIGQ	261	Q9BRB3
NLSRDMKSFPRKVLG	SPATA31A7	681	Q8IWB4
GKPSLRKQRFMQFSS	MICU2	81	Q8IYU8
AVQFRTPKADSSDKM	NEO1	1046	Q92859
ASLSFSEMKSREPKD	SIGLEC5	521	O15389
SMINLKTIASSADPK	SECISBP2	321	Q96T21
ASLMSAPKSLGSAFK	SLC26A10	6	Q8NG04
QLMSLSTADAKKDPS	PHYHIP	306	Q92561
ITKDFLPFMKSLSCN	SLCO1A2	301	P46721
LRKFPGSKLAEMFSS	KCTD14	51	Q9BQ13
RSSGSPKFAMKTRQA	MTA1	456	Q13330
KMKDRDSANSAPKTQ	PDGFRL	51	Q15198
DKSRSPISAKLVANM	PRPS1L1	101	P21108
KLSMFVLLPSHSKDN	SERPINB12	251	Q96P63
RDRPKSTLMNFSKVQ	STON2	276	Q8WXE9
SMKLQDSPLLSFSRS	RAX	201	Q9Y2V3
SCNKFPAIKAMLSID	TGM3	676	Q08188
SATFLTSSKKNMNLP	C1orf105	41	O95561
NFPGVKLRSKMSLRS	APC	81	P25054
MAAAKVALTKRADPA	SLC25A13	1	Q9UJS0
DSISPFNKSALKEAM	CLASP2	1026	O75122
GFFSPKSRAKIMSEQ	CNOT6L	261	Q96LI5
ASMKLANPATLLSLK	SHC4	91	Q6S5L8
NLSRDMKSFPRKVLG	SPATA31A3	681	Q5VYP0
KMVFAAAKASNRKPS	RNF213	2961	Q63HN8
PSKERMLLSFKLSSD	PDCD11	601	Q14690
PLSKMSLNKDLHFNT	TUBD1	326	Q9UJT1
MTVKPAKAASLARNL	RSPH3	1	Q86UC2
MSAKSAISKEIFAPL	STXBP6	1	Q8NFX7
MRPTADSFRLKKGNV	LINC02912	1	Q8N9X5
KPSLMFLAKAGSRDI	TAS1R3	111	Q7RTX0
LPSSKSFLGMKAREL	TSC1	1081	Q92574
SSGKLMSTDKAPLRQ	ZSWIM5	1096	Q9P217
KMQSDKGSIPDRFSA	TRBV13	81	A0A0A6YYD4
SDLRKISAMNVFPSN	WDFY3	726	Q8IZQ1
NLSRDMKSFPRKVLG	SPATA31A1	681	Q5TZJ5
NLSRDMKSFPRKVLG	SPATA31A5	681	Q5VU36
SFSKFLSASPMAPRK	SOWAHA	501	Q2M3V2
LAQMSKASPSSLLAK	TMEM94	346	Q12767
PRSKSEMLSRKNFAT	ILDR2	406	Q71H61
FAKPNDSRALQLMTK	THG1L	71	Q9NWX6
PKSFSDRQQMKDIRS	SOGA3	806	Q5TF21
MKFNPFVTSDRSKNR	RPL26	1	P61254
DKSRAPISAKLVANM	PRPS2	101	P11908
PSATRFRLDMLKNKA	TBC1D1	486	Q86TI0
TALTKPRAKSLSAMD	FGD6	596	Q6ZV73
SAASQMKRTGAIKPR	PRRC2B	2206	Q5JSZ5
MAKRKEENFSSPKNA	SMC6	1	Q96SB8
ASSMKDLAQKSFRLL	VPS13C	1741	Q709C8
NSTSKAAYVDKLMRP	PREX2	1461	Q70Z35
KDMSLINPSSSLKAE	TSTD2	26	Q5T7W7
FEDPRTKTKMSAAQA	PLEC	4496	Q15149
KTAAARKSLPASITM	NSD3	471	Q9BZ95
VPLDFSMSSLAKRIK	PMS2	616	P54278
KSGPLIFRKTMFNST	TMEM87B	56	Q96K49
SSNNKAMTDPSRKYL	USP37	226	Q86T82
NSRNSFMVIPKSKAS	TPRN	326	Q4KMQ1
SSANPSFKRLMKEAL	ZSWIM3	321	Q96MP5
NRLQSFPASKMAKLE	PHLPP1	1046	O60346
DKSRAPISAKLVANM	PRPS1	101	P60891
AKDKRLSTMQALPLA	SNAPC4	976	Q5SXM2
EATRILFFNTPKKMT	PSMD8	286	P48556
SNNMFSPLDLRASFK	ZBTB38	176	Q8NAP3
LMKDISQNFPIKARS	UGGT2	331	Q9NYU1
SMLKSTKFNSESRQP	HIVEP2	491	P31629
ASLARFSMKKSTSPE	ARHGAP21	1556	Q5T5U3
MKDLSQNFPTKARAI	UGGT1	346	Q9NYU2
RKPMDQKRSSSLGSN	ZC3H13	1181	Q5T200
KFAKNLLTSMPHDAI	TMEM260	421	Q9NX78
SRMTAEKFLNRLPKF	UBXN11	326	Q5T124
KRDLLQKSFALPEMS	UNC79	1746	Q9P2D8
GNLPAKLRKMNSDRF	KCNJ3	486	P48549
LMGAFASLDLKSQRK	LRFN2	656	Q9ULH4
RKMAKFSTPDLAANR	NACC1	201	Q96RE7
KKLVAAASPSAMLSQ	MYO9B	1316	Q13459