Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	RRM_1	SAFB RBM27 EIF4B	3.27e-03	208	27	3	PF00076
Domain	RRM	SAFB RBM27 EIF4B	3.68e-03	217	27	3	SM00360
Domain	RRM_dom	SAFB RBM27 EIF4B	4.18e-03	227	27	3	IPR000504
Domain	RRM	SAFB RBM27 EIF4B	4.33e-03	230	27	3	PS50102
Domain	-	DDR1 GLB1L3	4.96e-03	73	27	2	2.60.120.260
Domain	-	SAFB RBM27 EIF4B	5.11e-03	244	27	3	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	SAFB RBM27 EIF4B	5.96e-03	258	27	3	IPR012677
Domain	Galactose-bd-like	DDR1 GLB1L3	8.11e-03	94	27	2	IPR008979
Domain	C2	DYSF WWP1	1.53e-02	131	27	2	PF00168
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	DHX36 SAFB RBM27 YLPM1 SEC16A	1.23e-06	247	27	5	32989298
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	DHX36 SAFB RBM27 SEC16A	5.73e-05	274	27	4	34244482
Pubmed	TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.	NWD1 TOP3A	8.81e-05	18	27	2	32924931
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	DHX36 SAFB RBM27	9.47e-05	114	27	3	31553912
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	SAFB RBM27 EIF4B	1.40e-04	130	27	3	35545047
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	DHX36 RBM27 MRPS18B EIF4B SEC16A	1.57e-04	678	27	5	30209976
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	SAFB RBM27 YLPM1	2.05e-04	148	27	3	32538781
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	SMG9 DYSF RBM27 EIF4B YLPM1	2.13e-04	724	27	5	36232890
Pubmed	Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.	DDR1 MRPS18B	2.33e-04	29	27	2	16702430
Pubmed	Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.	EIF4B SEC16A	2.84e-04	32	27	2	19542561
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	DHX36 SAFB RBM27 EIF4B YLPM1	3.51e-04	807	27	5	22681889
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SMG9 RBM27 YLPM1 SEC16A	3.52e-04	440	27	4	34244565
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	RBM27 YLPM1 SEC16A	3.64e-04	180	27	3	35198878
Pubmed	Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.	RBM27 YLPM1 SEC16A	3.76e-04	182	27	3	32239614
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	SMG9 DHX36 SAFB EIF4B YLPM1 SEC16A	4.53e-04	1327	27	6	32694731
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SAFB RBM27 EIF4B YLPM1 SEC16A	6.82e-04	934	27	5	33916271
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SAFB RBM27 EIF4B YLPM1 SEC16A	7.51e-04	954	27	5	36373674
Cytoband	Ensembl 112 genes in cytogenetic band chr6p21	FRS3 DDR1 MRPS18B RSPH9	2.05e-04	503	27	4	chr6p21
Cytoband	6p21.1	FRS3 RSPH9	1.02e-03	80	27	2	6p21.1
GeneFamily	RNA binding motif containing	SAFB RBM27 EIF4B	1.83e-03	213	21	3	725
Disease	psoriatic arthritis	DDR1 MRPS18B	2.88e-03	87	27	2	EFO_0003778
Disease	gastroesophageal reflux disease	BTN1A1 YLPM1	3.85e-03	101	27	2	EFO_0003948
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	DYSF FAM20A	6.38e-03	131	27	2	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	DYSF FAM20A	6.38e-03	131	27	2	C4552091
Disease	Juvenile arthritis	DYSF FAM20A	6.38e-03	131	27	2	C3495559
Disease	Juvenile psoriatic arthritis	DYSF FAM20A	6.38e-03	131	27	2	C3714758

Protein segments in the cluster

Peptide	Gene	Start	Entry
FFTWRLYNERPRERR	BTN1A1	266	Q13410
RSYRLRYSRDGRRWM	DDR1	116	Q08345
WVRLRRDLGYYLARR	NWD1	631	Q149M9
ERNELYREKYDWRRG	RBM27	151	Q9P2N5
VDRYWAISRPFRYKR	DRD5	136	P21918
LYPLSSKRWRRRRYA	P2RY8	126	Q86VZ1
IRDYPRYLFEIRDWR	KIAA0100	1026	Q14667
YFRVPREYWRDRLLK	GLB1L3	96	Q8NCI6
RVRELYRAWYREVPN	NDUFA6	31	P56556
RNRAIWRQLRDYYPV	MOGAT3	81	Q86VF5
RREAVRWPYLCLRRY	FRS3	51	O43559
ERWPDYVRELRRRYS	DHX36	441	Q9H2U1
LEYRKTDAFRRRRWR	DYSF	1081	O75923
IQRWYRRYVARLEMR	PPEF2	26	O14830
DRYEDRYDRRDDRSW	EIF4B	296	P23588
KRDYRYDRVLFWGRI	RSPH9	36	Q9H1X1
EALRYYRRKVARWNR	FAM20A	121	Q96MK3
GRERDYIAPWERERR	SMG9	36	Q9H0W8
YYRARWELYDRSRDP	SGSH	431	P51688
RRPYDLDRRDDAYWP	SAFB	711	Q15424
ERYGSRPVWADYRRN	MRPS18B	66	Q9Y676
RLEWIFRRVLYRPYL	TRPM5	901	Q9NZQ8
VRDPRTYDRRYWCDA	SEC16A	1281	O15027
ATRWLRQYRPREYLA	SLC26A1	56	Q9H2B4
ARYALRWLRRPEDRA	TOP3A	6	Q13472
PPLDRYRDDRWREER	YLPM1	1341	P49750
GWERRVDDRRRVYYV	WWP1	386	Q9H0M0
YDRLLRIRALRWEYG	GINS1	81	Q14691