Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninhibitory MHC class I receptor activity

LILRB5 LILRB4

1.84e-0412342GO:0032396
GeneOntologyMolecularFunctioncalcium ion binding

LRP2 LTBP1 LTBP3 SUSD1 FSTL5 JAG1 LRP8

2.25e-04749347GO:0005509
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP2 LRP8

3.33e-0416342GO:0005041
GeneOntologyMolecularFunctionMHC class I receptor activity

LILRB5 LILRB4

4.23e-0418342GO:0032393
GeneOntologyMolecularFunctionprotein phosphatase binding

REG1A REG1B LILRB5 LILRB4

4.31e-04210344GO:0019903
GeneOntologyMolecularFunctionpeptidoglycan binding

REG1A REG1B

4.73e-0419342GO:0042834
GeneOntologyMolecularFunctionapolipoprotein binding

LRP8 LILRB4

5.25e-0420342GO:0034185
GeneOntologyMolecularFunctionoligosaccharide binding

REG1A REG1B

5.25e-0420342GO:0070492
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP2 LRP8

5.79e-0421342GO:0030228
GeneOntologyMolecularFunctiontransforming growth factor beta binding

LTBP1 LTBP3

8.91e-0426342GO:0050431
GeneOntologyMolecularFunctionphosphatase binding

REG1A REG1B LILRB5 LILRB4

1.01e-03264344GO:0019902
GeneOntologyMolecularFunctiongrowth factor binding

LRP2 LTBP1 LTBP3

2.34e-03156343GO:0019838
GeneOntologyMolecularFunctiongrowth factor activity

REG1A REG1B JAG1

3.14e-03173343GO:0008083
GeneOntologyMolecularFunctioncell adhesion molecule binding

ADGRL1 FAP CD226 LILRB5 LILRB4

3.23e-03599345GO:0050839
GeneOntologyMolecularFunctionintegrin binding

FAP CD226 LILRB4

3.24e-03175343GO:0005178
GeneOntologyBiologicalProcesspancreas regeneration

REG1A REG1B

2.48e-062332GO:1990798
GeneOntologyBiologicalProcesspositive regulation of acinar cell proliferation

REG1A REG1B

7.44e-063332GO:1904699
GeneOntologyBiologicalProcessacinar cell proliferation

REG1A REG1B

2.47e-055332GO:1990863
GeneOntologyBiologicalProcessregulation of acinar cell proliferation

REG1A REG1B

2.47e-055332GO:1904697
GeneOntologyBiologicalProcesspulmonary artery morphogenesis

LRP2 JAG1

3.71e-056332GO:0061156
GeneOntologyBiologicalProcesspositive regulation of type B pancreatic cell proliferation

REG1A REG1B

6.91e-058332GO:1904692
GeneOntologyCellularComponentdendrite

LRP2 CACNA1S REG1A REG1B LTBP1 GLRB RAB3IP LRP8

1.04e-04858378GO:0030425
GeneOntologyCellularComponentcell surface

LRP2 FAP CPM CD226 LILRB5 GOT2 GLRB LRP8 LILRB4

1.06e-041111379GO:0009986
GeneOntologyCellularComponentdendritic tree

LRP2 CACNA1S REG1A REG1B LTBP1 GLRB RAB3IP LRP8

1.06e-04860378GO:0097447
GeneOntologyCellularComponentsomatodendritic compartment

LRP2 CACNA1S REG1A REG1B LTBP1 GOT2 GLRB RAB3IP LRP8

2.25e-041228379GO:0036477
GeneOntologyCellularComponentgrowth cone

LRP2 ADGRL1 REG1A REG1B

8.97e-04245374GO:0030426
GeneOntologyCellularComponentsite of polarized growth

LRP2 ADGRL1 REG1A REG1B

1.01e-03253374GO:0030427
GeneOntologyCellularComponentzymogen granule

REG1A REG1B

1.46e-0332372GO:0042588
GeneOntologyCellularComponentexternal side of plasma membrane

LRP2 CD226 LILRB5 GLRB LILRB4

2.09e-03519375GO:0009897
GeneOntologyCellularComponentneuronal cell body membrane

REG1A REG1B

2.63e-0343372GO:0032809
GeneOntologyCellularComponentcell body membrane

REG1A REG1B

3.13e-0347372GO:0044298
GeneOntologyCellularComponentside of membrane

LRP2 CPM CD226 LILRB5 GLRB LILRB4

4.05e-03875376GO:0098552
GeneOntologyCellularComponentdendrite membrane

REG1A REG1B

4.42e-0356372GO:0032590
GeneOntologyCellularComponentaxon

LRP2 ADGRL1 REG1A REG1B MYCBP2 LRP8

4.42e-03891376GO:0030424
GeneOntologyCellularComponentcell body

REG1A REG1B LTBP1 RPE65 GOT2 LRP8

5.41e-03929376GO:0044297
MousePhenodelayed liver regeneration

REG1A REG1B

5.77e-056282MP:0031324
MousePhenoiris coloboma

LTBP3 JAG1

1.38e-049282MP:0010714
MousePhenoshort snout

LRP2 LTBP1 LTBP3 JAG1

1.46e-04136284MP:0000445
MousePhenosmall snout

LRP2 LTBP1 LTBP3 JAG1

1.82e-04144284MP:0030190
MousePhenouveal coloboma

LTBP3 JAG1

2.10e-0411282MP:0012533
DomainEGF_CA

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

9.68e-0986346PF07645
DomainEGF_Ca-bd_CS

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

2.01e-0897346IPR018097
DomainEGF_CA

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

2.27e-0899346PS01187
DomainASX_HYDROXYL

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

2.41e-08100346PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

3.42e-08106346IPR000152
DomainEGF_CA

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

7.95e-08122346SM00179
DomainEGF-like_Ca-bd_dom

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

8.76e-08124346IPR001881
DomainGrowth_fac_rcpt_

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

3.42e-07156346IPR009030
DomainEGF_3

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

3.73e-06235346PS50026
DomainEGF

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

3.73e-06235346SM00181
DomainEGF-like_dom

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

5.20e-06249346IPR000742
DomainEGF_1

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

5.96e-06255346PS00022
DomainEGF-like_CS

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

6.81e-06261346IPR013032
DomainEGF_2

LRP2 LTBP1 LTBP3 SUSD1 JAG1 LRP8

7.43e-06265346PS01186
DomaincEGF

LRP2 LTBP1 LTBP3

1.39e-0526343IPR026823
DomaincEGF

LRP2 LTBP1 LTBP3

1.39e-0526343PF12662
DomainTB

LTBP1 LTBP3

6.72e-057342PF00683
DomainEGF

LRP2 LTBP1 JAG1 LRP8

7.83e-05126344PF00008
Domain-

LTBP1 LTBP3

8.95e-0583423.90.290.10
DomainTB

LTBP1 LTBP3

1.15e-049342PS51364
DomainTB_dom

LTBP1 LTBP3

1.15e-049342IPR017878
DomainLdl_recept_b

LRP2 LRP8

2.89e-0414342PF00058
DomainLDLRB

LRP2 LRP8

2.89e-0414342PS51120
DomainLY

LRP2 LRP8

3.33e-0415342SM00135
DomainLDLR_classB_rpt

LRP2 LRP8

3.33e-0415342IPR000033
DomainhEGF

LTBP3 JAG1

1.18e-0328342PF12661
Domain-

LRP2 LRP8

2.29e-03393422.120.10.30
DomainLDLR_class-A_CS

LRP2 LRP8

2.40e-0340342IPR023415
DomainC-type_lectin_CS

REG1A REG1B

2.77e-0343342IPR018378
DomainLdl_recept_a

LRP2 LRP8

3.03e-0345342PF00057
Domain-

LRP2 LRP8

3.17e-03463424.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP2 LRP8

3.17e-0346342IPR011042
DomainLDLRA_1

LRP2 LRP8

3.44e-0348342PS01209
DomainLDrepeatLR_classA_rpt

LRP2 LRP8

3.59e-0349342IPR002172
DomainLDLa

LRP2 LRP8

3.59e-0349342SM00192
DomainLDLRA_2

LRP2 LRP8

3.59e-0349342PS50068
Domainig

LILRB5 FSTL5 LILRB4

4.92e-03190343PF00047
DomainImmunoglobulin

LILRB5 FSTL5 LILRB4

4.92e-03190343IPR013151
DomainEGF_extracell

LRP2 JAG1

5.33e-0360342IPR013111
DomainEGF_2

LRP2 JAG1

5.33e-0360342PF07974
Domain-

MYCBP2 CD226 LILRB5 FSTL5 LILRB4

6.58e-036633452.60.40.10
DomainIG

CD226 LILRB5 FSTL5 LILRB4

6.92e-03421344SM00409
DomainIg_sub

CD226 LILRB5 FSTL5 LILRB4

6.92e-03421344IPR003599
DomainIg_2

LILRB5 LILRB4

7.80e-0373342PF13895
DomainIg-like_fold

MYCBP2 CD226 LILRB5 FSTL5 LILRB4

8.53e-03706345IPR013783
DomainIGc2

CD226 LILRB5 FSTL5

8.83e-03235343SM00408
DomainIg_sub2

CD226 LILRB5 FSTL5

8.83e-03235343IPR003598
DomainC_TYPE_LECTIN_1

REG1A REG1B

9.30e-0380342PS00615
DomainLectin_C

REG1A REG1B

1.02e-0284342PF00059
DomainCLECT

REG1A REG1B

1.02e-0284342SM00034
DomainC_TYPE_LECTIN_2

REG1A REG1B

1.04e-0285342PS50041
DomainC-type_lectin-like

REG1A REG1B

1.07e-0286342IPR001304
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

LTBP1 LTBP3

9.82e-058272M47850
Pubmed

Prognostic role of regenerating gene-I in patients with stage-IV head and neck squamous cell carcinoma.

REG1A REG1B

1.04e-06236227539087
Pubmed

Helicobacter and gastrin stimulate Reg1 expression in gastric epithelial cells through distinct promoter elements.

REG1A REG1B

1.04e-06236217463184
Pubmed

The expression of REG 1A and REG 1B is increased during acute amebic colitis.

REG1A REG1B

1.04e-06236221586335
Pubmed

Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats.

REG1A REG1B

1.04e-06236224587207
Pubmed

Mechanism of calcite crystal growth inhibition by the N-terminal undecapeptide of lithostathine.

REG1A REG1B

1.04e-06236210625646
Pubmed

Partial amino acid sequence of human pancreatic stone protein, a novel pancreatic secretory protein.

REG1A REG1B

1.04e-0623623541906
Pubmed

Reg2 Expression Is Required for Pancreatic Islet Compensation in Response to Aging and High-Fat Diet-Induced Obesity.

REG1A REG1B

1.04e-06236228009527
Pubmed

Exacerbation of indomethacin-induced small intestinal injuries in Reg I-knockout mice.

REG1A REG1B

1.04e-06236220508157
Pubmed

Differential expression of reg-I and reg-II genes during aging in the normal mouse.

REG1A REG1B

1.04e-0623628808978
Pubmed

Preferential expression of reg I beta gene in human adult pancreas.

REG1A REG1B

1.04e-06236211396963
Pubmed

Cellular mechanisms underlying failed beta cell regeneration in offspring of protein-restricted pregnant mice.

REG1A REG1B

1.04e-06236223986224
Pubmed

What function for human lithostathine?: structural investigations by three-dimensional structure modeling and high-resolution NMR spectroscopy.

REG1A REG1B

1.04e-0623628961348
Pubmed

Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation.

REG1A REG1B

1.04e-06236217898082
Pubmed

Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene.

REG1A REG1B

1.04e-0623622332435
Pubmed

The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic beta-cells.

REG1A REG1B

1.04e-06236210526060
Pubmed

Crucial role of Reg I from acinar-like cell cluster touching with islets (ATLANTIS) on mitogenesis of beta cells in EMC virus-induced diabetic mice.

REG1A REG1B

1.04e-06236229935186
Pubmed

Expression of Reg family genes in the gastrointestinal tract of mice treated with indomethacin.

REG1A REG1B

1.04e-06236225747353
Pubmed

Complete amino acid sequence of an immunoreactive form of human pancreatic stone protein isolated from pancreatic juice.

REG1A REG1B

1.04e-0623623665916
Pubmed

Enhanced expression of an exocrine pancreatic protein in Alzheimer's disease and the developing human brain.

REG1A REG1B

1.04e-0623622394826
Pubmed

Synergistic activations of REG I α and REG I β promoters by IL-6 and Glucocorticoids through JAK/STAT pathway in human pancreatic β cells.

REG1A REG1B

1.04e-06236225767811
Pubmed

RegII is a beta-cell protein and autoantigen in diabetes of NOD mice.

REG1A REG1B

1.04e-06236217192462
Pubmed

Isolation, structural determination and expression of a novel reg gene, human regI beta.

REG1A REG1B

1.04e-0623628110835
Pubmed

Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation.

REG1A REG1B

1.04e-0623628654365
Pubmed

In vivo evidence for the role of RegI in gastric regeneration: transgenic overexpression of RegI accelerates the healing of experimental gastric ulcers.

REG1A REG1B

1.04e-06236220157293
Pubmed

No abnormalities of reg1 alpha and reg1 beta gene associated with diabetes mellitus.

REG1A REG1B

1.04e-06236211796176
Pubmed

Isolation, characterization, and distribution of an unusual pancreatic human secretory protein.

REG1A REG1B

1.04e-0623623908481
Pubmed

Secretory pancreatic stone protein messenger RNA. Nucleotide sequence and expression in chronic calcifying pancreatitis.

REG1A REG1B

1.04e-0623622525567
Pubmed

Cleavage of the Arg-Ile bond in the native polypeptide chain of human pancreatic stone protein.

REG1A REG1B

1.04e-0623623108036
Pubmed

The human reg gene encodes pancreatic stone protein.

REG1A REG1B

1.04e-0623622764894
Pubmed

Protein-X, Pancreatic Stone-, Pancreatic thread-, reg-protein, P19, lithostathine, and now what? Characterization, structural analysis and putative function(s) of the major non-enzymatic protein of pancreatic secretions.

REG1A REG1B

1.04e-06236212369899
Pubmed

Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice.

REG1A REG1B

1.04e-06236217133485
Pubmed

Reg2 protects mouse insulinoma cells from streptozotocin-induced mitochondrial disruption and apoptosis.

REG1A REG1B

1.04e-06236220919961
Pubmed

A gene homologous to the reg gene is expressed in the human pancreas.

REG1A REG1B

1.04e-0623628348956
Pubmed

Pancreatic acinar-specific overexpression of Reg2 gene offered no protection against either experimental diabetes or pancreatitis in mice.

REG1A REG1B

1.04e-06236220489047
Pubmed

Reg I protein in healthy and seminoma human testis.

REG1A REG1B

1.04e-06236218712671
Pubmed

Diabetes and tumor formation in transgenic mice expressing Reg I.

REG1A REG1B

1.04e-06236211097844
Pubmed

mReg2 inhibits nuclear entry of apoptosis-inducing factor in mouse insulinoma cells.

REG1A REG1B

1.04e-06236225370781
Pubmed

Pancreatic regenerating gene overexpression in the nonobese diabetic mouse during active diabetogenesis.

REG1A REG1B

1.04e-0623628522062
Pubmed

A novel gene activated in regenerating islets.

REG1A REG1B

1.04e-0623622963000
Pubmed

Structure, chromosomal localization, and expression of mouse reg genes, reg I and reg II. A novel type of reg gene, reg II, exists in the mouse genome.

REG1A REG1B

1.04e-0623628340418
Pubmed

N-terminal sequence extension in the glycosylated forms of human pancreatic stone protein. The 5-oxoproline N-terminal chain is O-glycosylated on the 5th amino acid residue.

REG1A REG1B

1.04e-0623622493268
Pubmed

Isolation and characterization of human reg protein produced in Saccharomyces cerevisiae.

REG1A REG1B

1.04e-0623622226837
Pubmed

Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice.

REG1A REG1B

1.04e-06236212475793
Pubmed

Keratinocyte Regnase-1, a Downregulator of Skin Inflammation, Contributes to Protection against Tumor Promotion by Limiting Cyclooxygenase-2 Expression.

REG1A REG1B

3.12e-06336236470473
Pubmed

Regenerating gene I regulates interleukin-6 production in squamous esophageal cancer cells.

REG1A REG1B

3.12e-06336220056108
Pubmed

Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction.

REG1A REG1B

3.12e-06336236063729
Pubmed

Regenerating islet-derived 1α (Reg-1α) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptor.

REG1A REG1B

3.12e-06336222158612
Pubmed

Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells.

REG1A REG1B

3.12e-06336230914711
Pubmed

Human regeneration protein/lithostathine genes map to chromosome 2p12.

REG1A REG1B

3.12e-0633628333731
Pubmed

Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells.

LRP2 LRP8

3.12e-06336218174160
Pubmed

Attenuation of unfolded protein response and apoptosis by mReg2 induced GRP78 in mouse insulinoma cells.

REG1A REG1B

3.12e-06336224801175
Pubmed

Cyclin D1 activation through ATF-2 in Reg-induced pancreatic beta-cell regeneration.

REG1A REG1B

3.12e-06336216405968
Pubmed

Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3).

LTBP1 LTBP3

3.12e-0633627730318
Pubmed

Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells.

LTBP1 LTBP3

3.12e-06336218672106
Pubmed

Loss of RegI in conjunction with gastrin deficiency in mice facilitates efficient gastric ulcer healing but is dispensable for hyperplasia and tumourigenesis.

REG1A REG1B

3.12e-06336219969026
Pubmed

Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.

LTBP1 LTBP3

3.12e-06336210743502
Pubmed

Role of regenerating gene I in claudin expression and barrier function in the small intestine.

REG1A REG1B

6.24e-06436227055226
Pubmed

Expression of Reg family proteins in embryonic stem cells and its modulation by Wnt/beta-catenin signaling.

REG1A REG1B

6.24e-06436220050810
Pubmed

REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation.

REG1A REG1B

6.24e-06436223519454
Pubmed

Regenerating (reg) and insulin genes are expressed in prepancreatic mouse embryos.

REG1A REG1B

6.24e-0643628863190
Pubmed

Maternal-fetal transfer of selenium in the mouse.

LRP2 LRP8

6.24e-06436223651543
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP1 LTBP3

6.24e-06436215611103
Pubmed

Reg3β deficiency impairs pancreatic tumor growth by skewing macrophage polarization.

REG1A REG1B

6.24e-06436223867474
Pubmed

Transcriptional activation of Reg2 and Reg3β genes by glucocorticoids and interleukin-6 in pancreatic acinar and islet cells.

REG1A REG1B

6.24e-06436223147030
Pubmed

Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice.

REG1A REG1B

6.24e-06436222252863
Pubmed

MicroRNA-7 directly targets Reg1 in pancreatic cells.

REG1A REG1B

6.24e-06436231166710
Pubmed

Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration.

LRP2 LRP8

6.24e-06436224760755
Pubmed

Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart.

LTBP1 LTBP3

6.24e-0643629008713
Pubmed

The latent transforming growth factor beta binding protein (LTBP) family.

LTBP1 LTBP3

6.24e-06436211104663
Pubmed

Regnase-1, an Immunomodulator, Limits the IL-36/IL-36R Autostimulatory Loop in Keratinocytes to Suppress Skin Inflammation.

REG1A REG1B

6.24e-06436229339122
Pubmed

Adjuvant immunotherapy increases beta cell regenerative factor Reg2 in the pancreas of diabetic mice.

REG1A REG1B

6.24e-06436220876350
Pubmed

Coordinated age-dependent and pancreatic-specific expression of mouse Reg2Reg3α, and Reg3β genes.

REG1A REG1B

6.24e-06436221410322
Pubmed

The pancreas responds to remote damage and systemic stress by secretion of the pancreatic secretory proteins PSP/regI and PAP/regIII.

REG1A REG1B

6.24e-06436228415799
Pubmed

Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.

LTBP1 LTBP3

6.24e-06436216157329
Pubmed

Identification of a novel Reg family gene, Reg IIIdelta, and mapping of all three types of Reg family gene in a 75 kilobase mouse genomic region.

REG1A REG1B

6.24e-06436210767532
Pubmed

Reg I-knockout mice reveal its role in regulation of cell growth that is required in generation and maintenance of the villous structure of small intestine.

REG1A REG1B

1.04e-05536216909126
Pubmed

Deletion of the mouse RegIIIbeta (Reg2) gene disrupts ciliary neurotrophic factor signaling and delays myelination of mouse cranial motor neurons.

REG1A REG1B

1.04e-05536218678917
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP2 LRP8

1.04e-05536216101684
Pubmed

Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm.

LTBP1 LTBP3

1.04e-05536219897194
Pubmed

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation.

REG1A REG1B

1.04e-05536227524624
Pubmed

Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma.

REG1A REG1B

1.04e-0553629055810
Pubmed

Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction.

REG1A REG1B

1.56e-05636229850784
Pubmed

Mapping of 20 polymorphic DNA markers in the rat by somatic hybrid and linkage analysis.

REG1A REG1B

1.56e-0563628903735
Pubmed

A novel upregulation of glutathione peroxidase 1 by knockout of liver-regenerating protein Reg3β aggravates acetaminophen-induced hepatic protein nitration.

REG1A REG1B

1.56e-05636223811004
Pubmed

Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2.

REG1A REG1B

1.56e-05636223269672
Pubmed

Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.

LTBP1 LTBP3

2.18e-05736210930463
Pubmed

Differential expression of leukocyte immunoglobulin-like receptors on cord-blood-derived human mast cell progenitors and mature mast cells.

LILRB5 LILRB4

2.18e-05736217998301
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP2 LRP8

2.18e-05736212169628
Pubmed

A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

LILRB5 LILRB4

2.91e-0583629548455
Pubmed

Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.

LTBP1 LTBP3

2.91e-05836227339457
Pubmed

Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites.

REG1A REG1B

2.91e-05836234375000
Pubmed

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development.

REG1A REG1B

3.73e-05936237395395
Pubmed

The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1.

REG1A REG1B

3.73e-05936222037600
Pubmed

Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome.

LRP2 JAG1

4.66e-051036230046000
Pubmed

Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development.

LILRB5 LILRB4

4.66e-051036218802077
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

LRP2 MYCBP2

5.70e-051136223968836
Pubmed

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

LRP2 JAG1

5.70e-051136222999937
Pubmed

Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis.

REG1A REG1B

6.83e-051236218297134
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP2 LRP8

9.41e-051436217389516
Pubmed

Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling.

LTBP1 LTBP3

1.08e-041536217804598
CytobandEnsembl 112 genes in cytogenetic band chr2p12

REG1A REG1B

9.14e-0455372chr2p12
CytobandEnsembl 112 genes in cytogenetic band chr12q15

CPM RAB3IP

9.47e-0456372chr12q15
Cytoband21q22.11

KRTAP20-3 KRTAP22-2

1.16e-036237221q22.11
Cytoband19q13.4

LILRB5 LILRB4

1.87e-037937219q13.4
Cytoband2p12

REG1A REG1B

4.05e-031173722p12
CytobandEnsembl 112 genes in cytogenetic band chr4q32

FSTL5 GLRB

4.25e-03120372chr4q32
CytobandEnsembl 112 genes in cytogenetic band chr1p32

LRP8 USP24

6.98e-03155372chr1p32
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP1 LTBP3

1.49e-054292628
GeneFamilyCD molecules|Inhibitory leukocyte immunoglobulin like receptors

LILRB5 LILRB4

2.48e-0552921182
GeneFamilyLow density lipoprotein receptors

LRP2 LRP8

1.92e-0413292634
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

REG1A REG1B

1.96e-03412921298
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CD226 LILRB5 JAG1 LILRB4

3.43e-03394294471
GeneFamilyKeratin associated proteins

KRTAP20-3 KRTAP22-2

1.31e-02109292619
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_100

FAP ARSJ GLRB

1.00e-0460323gudmap_developingKidney_e15.5_Peripheral blastema_100_k3
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_1000

LRP2 LTBP1 PLPP2 MYCBP2 JAG1 RAB3IP CYYR1

1.69e-04811327gudmap_developingKidney_e15.5_S-shaped body_1000
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500

FAP LTBP3 ARSJ GLRB

1.76e-04188324gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3
CoexpressionAtlasalpha beta T cells, T.4.PLN.BDC, 4+ 8- BDC+, Lymph Node, avg-3

ADGRL1 CPM CD226

1.95e-0475323GSM605758_100
CoexpressionAtlasalpha beta T cells, T.4.LN.BDC, 4+ 8- BDC+, Lymph Node, avg-3

ADGRL1 CPM CD226

1.95e-0475323GSM605753_100
CoexpressionAtlasalpha beta T cells, T.4.Pa.BDC, 4+ 8- BDC+, Pancreas, avg-2

ADGRL1 CPM CD226

2.19e-0478323GSM605756_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

LTBP1 CPM JAG1 GLRB LRP8

2.33e-04377325gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#2_top-relative-expression-ranked_200

FAP ARSJ GLRB

2.54e-0482323gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_200_k2
CoexpressionAtlasCD positive, CD4 Control, 4+ 8- B220-, Spleen, avg-4

ADGRL1 CPM CD226 RAB3IP

2.69e-04210324GSM403995_500
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_100

FAP ARSJ GLRB

3.02e-0487323gudmap_developingKidney_e15.5_Peripheral blastema_100
CoexpressionAtlasDevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_500

LRP2 PLPP2 SUSD1 FSTL5 LRP8

3.10e-04401325gudmap_developingKidney_e11.5_ureteric bud_500
CoexpressionAtlasCD positive, CD4 Control, 4+8-B220-, Spleen, avg-2

ADGRL1 CPM CD226 RAB3IP

3.44e-04224324GSM403994_500
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAP LTBP1 KIR3DX1 PLPP2

1.18e-05170374dfef8f79960979335b86b4730f224239b40735d5
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAP LTBP1 KIR3DX1 PLPP2

1.18e-05170374fb6098137d010175978596bc382e9ecba9c3891e
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSD3B7 LTBP1 ARSJ JAG1

1.32e-051753742e54961846c65b185d9bd6e305dd81205579d890
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSD3B7 LTBP1 ARSJ JAG1

1.32e-05175374efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.57e-05183374c5b10571599dc26476170b54b53f09c23e6b3117
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP1 ARSJ JAG1 CYYR1

1.68e-051863742d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

LTBP1 LTBP3 ARSJ JAG1

1.75e-051883742777eb7689b271c199021fe7d9db88ccebff14de
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.86e-0519137405731ece7867659c662f952812805f947032fe10
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.90e-05192374b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.94e-05193374b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.94e-05193374b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCellPCW_05-06-Epithelial-Epithelial_airway|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.94e-05193374af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.94e-05193374de569c6e507856fd3ac2311f246cb597074ed30c
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.98e-05194374b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCellPCW_05-06-Epithelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.98e-0519437447a1369c22fcbfe00b08376eb610a61c355548db
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LRP2 CPM PLPP2 FSTL5

1.98e-05194374f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSD3B7 LTBP1 LTBP3 ARSJ

2.19e-0519937485bb28369e0568b7b3bda095722102fc793f60ef
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HSD3B7 CPM LILRB5 LILRB4

2.19e-0519937454a54ad983503ed515d476882d86b17d97892037
ToppCellSevere-Myeloid-Macrophages-FCN1-SPP1+|Severe / Condition, Lineage, Cell class and cell subclass

HSD3B7 CPM LILRB5 LILRB4

2.23e-05200374b8cd209b810312793465b28bb2a6cbe5d94da91f
ToppCellMonocytes-C1QA+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ZNF80 LTBP1 LILRB5

4.50e-0583373336137d527d57ebd24670df3d19c62ed889b99e3
ToppCellPBMC-Mild-cDC_7|Mild / Compartment, Disease Groups and Clusters

LTBP1 LILRB5 JAG1

2.21e-0414237358f66f35646f281e64d634e6c26adbd1d4e6c830
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP2 SUSD1 LILRB4

2.40e-04146373bee5074c29b132180d35f57d307e342efa9b8cd1
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LTBP1 JAG1

2.75e-041533730ef7c45cdd854c79e527006034029767f8e108b2
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD226 FSTL5 LILRB4

3.08e-04159373323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD1 CD226 RAB3IP

3.31e-041633734af92b211d12c5b88b65bb746242cd702b545bd0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L5_RORB_SNHG7|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARSJ DNAH6 FSTL5

3.31e-041633736ed2a71385e85508ed513282c06440add7cc010c
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD1 CD226 RAB3IP

3.31e-04163373d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAP JAG1 CYYR1

3.43e-04165373a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellNS-critical-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SUSD1 CYYR1 LILRB4

3.43e-0416537317d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

SUSD1 LRP8 LILRB4

3.56e-041673731e2fc1637769405a61f4c7e44945712a1888a299
ToppCellNS-moderate-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SUSD1 CYYR1 LILRB4

3.62e-04168373d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCell10x5'-GI_small-bowel-Myeloid_Mac-Macrophage|GI_small-bowel / Manually curated celltypes from each tissue

CPM LILRB5 LILRB4

3.62e-04168373d5b746d6083c2c8155a0ea345ea368bf6617d5ca
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARSJ DNAH6 FSTL5

3.62e-04168373bfa1491e8d433933003778b274710d3a16d973cb
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

SUSD1 CYYR1 LILRB4

3.62e-04168373cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAP JAG1 CYYR1

3.68e-04169373c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellMyeloid-Myeloid-D_(Mast_cell)|Myeloid / shred on cell class and cell subclass (v4)

SUSD1 CD226 LILRB4

3.81e-041713735f1aafc4c55a9c6c3153430186a8a351425a3cb9
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

LRP2 REG1A REG1B

3.81e-04171373f28684ea0e74a22f4c140658496068e28a6d3605
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

SUSD1 CYYR1 LILRB4

3.81e-0417137372c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

SUSD1 CYYR1 LILRB4

3.81e-041713731f8e66073088fc1969782e443bf00f8c1877ea91
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

SUSD1 CYYR1 LILRB4

3.88e-041723733ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

SUSD1 CYYR1 LILRB4

3.88e-04172373a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARSJ DNAH6 FSTL5

3.94e-04173373ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SUSD1 CD226 LILRB4

3.94e-041733738ca650542655c27516029e5bace97ff1b9dcc256
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD1 LRP8 LILRB4

3.94e-041733733612772632ddf11eb48579cae9a8ccab6b3f1f52
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SUSD1 CD226 LILRB4

3.94e-041733734282b47b33325472f52a4085986988911a372ed8
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD1 LRP8 LILRB4

3.94e-041733734dc261ebcdb9bdcfca1451da1bd254f0dc5de203
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAP LTBP1 JAG1

4.01e-04174373778e0317c0c63fa4efd74114feb760975b819d92
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARSJ FSTL5 LRP8

4.01e-0417437399eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CPM LILRB5 RAB3IP

4.08e-041753732eca4c168dea2017ea0e383006e28abed22f32ec
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SUSD1 CYYR1 LILRB4

4.08e-0417537397fe431f224b592b3076632d101e19136c138dcc
ToppCellfacs-Skin-nan-18m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH6 FSTL5 JAG1

4.15e-04176373086197acbfec4ac0c15b7e9721871aaa9e32e219
ToppCellE12.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CACNA1S FAP JAG1

4.22e-041773735cdf413f82376a95467322b16d10b0d1e7557e2d
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAP IGLV7-43 CYYR1

4.22e-04177373fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

SUSD1 CYYR1 LILRB4

4.22e-0417737343e1d0d3cf8f0c02e67d91f8dd1761df23d59e07
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP1 CPM JAG1

4.22e-04177373a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAP IGLV7-43 CYYR1

4.22e-0417737312f8627124acbf436e75681ff1ce429ff5e3f256
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP1 CPM JAG1

4.22e-041773733645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellControl-T/NK-NK|Control / Disease group,lineage and cell class (2021.01.30)

ADGRL1 ZNF80 CD226

4.29e-04178373079fd19bdeed86bf985c4083af432432d66ad546
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARSJ DNAH6 FSTL5

4.36e-04179373b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

REG1A REG1B PLPP2

4.36e-041793736405010e8136a4d9bab356f628e36e3194911112
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

HSD3B7 LILRB5 LILRB4

4.36e-04179373b4430f633711cecf793e8e76e766a66ff1eff473
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

HSD3B7 LILRB5 LILRB4

4.43e-041803737be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellmoderate-Myeloid-pDC|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SUSD1 CYYR1 LILRB4

4.43e-04180373a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SUSD1 CYYR1 LILRB4

4.43e-04180373144818e69613296cde43f29cb8c20899c670b319
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAP IGLV7-43 CYYR1

4.43e-04180373be9d99a2e22e63824fb2a91974379da45160ae43
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.50e-04181373a8e9ea73c24109a5d4d28bc0577cc869ad932a4d
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.57e-04182373d524ad5cf00f05ee27c9db2ffa2d4e30a1e2e21a
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRL1 SUSD1 LILRB4

4.57e-0418237302c0824373a0ecebc922d4ca848ace9d570722c4
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARSJ FSTL5 JAG1

4.57e-04182373ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARSJ FSTL5 JAG1

4.57e-0418237347ff6b4002a4167412c79210651316d1342503f9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LTBP1 FSTL5 RAB3IP

4.65e-04183373f8b636391f752e379a5c5575fd898bdf0907a3b8
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.65e-041833735472cdce6d99314d229418412acf1fff6340db7d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.65e-0418337393213124e55d1b673dd345188caf8b5bd31d99fe
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.72e-04184373f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPM CD226 RAB3IP

4.72e-04184373cdacb61878e0824b8416bf365d89965797208359
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.72e-041843735939527d24d299e562e707469c9123890edd76be
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LTBP1 FSTL5 RAB3IP

4.72e-04184373ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.72e-04184373a2191dd5546efd357b23e625beb3c5820476f243
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

LTBP1 ARSJ JAG1

4.72e-04184373b4c561924c508536fd2112e91e32176b95fdf63a
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.79e-04185373b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCelldroplet-Marrow-nan-18m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL1 LTBP1 LTBP3

4.79e-04185373de353368f4f6a7a0a66e391d586879876fbe2734
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SUSD1 CYYR1 LILRB4

4.79e-041853733091870a5bf8ecb963e560b47c8502bae367416c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.79e-041853731d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.79e-04185373b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCellICU-NoSEP-Myeloid-pDC|ICU-NoSEP / Disease, Lineage and Cell Type

SUSD1 CYYR1 LILRB4

4.79e-041853737564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SUSD1 CYYR1 LILRB4

4.87e-04186373a07694caf7fede06a47636725bcc7f09909cdf07
ToppCellMultiple_Sclerosis-Myeloid-pDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

SUSD1 CYYR1 LILRB4

4.87e-04186373330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LTBP1 FSTL5 RAB3IP

4.87e-0418637377592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.87e-04186373d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.87e-0418637390eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP1 LRP8 CYYR1

4.87e-0418637392092f11ecce22c14f244e42c499af0822977e6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LTBP1 RPE65 JAG1

4.87e-041863734780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.87e-04186373bd8a9753df219084e19e7f94447856e86608325c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRP2 CPM PLPP2

4.95e-04187373f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCellfacs-Heart-LA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP CPM JAG1

4.95e-04187373a12f383b02b07af32cc53a154685df8dba8fbd3f
ToppCellIIH-pDC-|IIH / Condition, Cell_class and T cell subcluster

SUSD1 CYYR1 LILRB4

4.95e-04187373ad87b146ea8dd9f695e722f8f0e8e1057c7f3167
ToppCellfacs-Heart-LA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP CPM JAG1

4.95e-04187373c40c152fa14e6afc9188549534b64ccbaded56b3
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(2)_5-FU / Stress and Cell class

FAP LTBP1 MYCBP2

4.95e-041873736bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP1 CPM JAG1

4.95e-04187373ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSD3B7 ARSJ CYYR1

4.95e-041873736cf7be5401b81a4eeb30840fb3733d61a24af539
DiseaseEye Diseases, Hereditary

LRP2 RPE65

1.93e-056342C0015398
Diseaselithostathine-1-alpha measurement

REG1A REG1B

2.70e-057342EFO_0801083
Diseaseobsolete_interleukin-1 alpha measurement

REG1A REG1B

2.70e-057342EFO_0802653
DiseaseBone Diseases

LTBP3 JAG1

5.77e-0510342C0005940
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

CACNA1S FAP FSTL5 USP24

1.09e-04216344EFO_0007925, EFO_0007927
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 1 measurement

KIR3DX1 LILRB4

1.34e-0415342EFO_0008208
DiseaseNystagmus

REG1A REG1B

2.67e-0421342HP_0000639
Diseasecomplement factor H-related protein 2 measurement

REG1A REG1B

5.13e-0429342EFO_0600055
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma

REG1A ARSJ

9.30e-0439342EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Diseasecolon cancer (biomarker_via_orthology)

REG1A REG1B

9.30e-0439342DOID:219 (biomarker_via_orthology)
Diseaseglycerophospholipid measurement

ARSJ CYYR1

1.46e-0349342EFO_0007630
Diseaseurate measurement, spine bone mineral density

ADGRL1 LTBP1

2.05e-0358342EFO_0004531, EFO_0007701
Diseaseosteoarthritis

LTBP1 KMT5A FSTL5

2.12e-03222343MONDO_0005178

Protein segments in the cluster

PeptideGeneStartEntry
VYFCYDGSPYRSYED

HSD3B7

256

Q9H2F3
SRTKYYYLGGYCFPA

ADGRL1

961

O94910
GDSSNYYYISPFCRY

RAB3IP

411

Q96QF0
GMACRSGKYYFYDNY

NT5DC1

116

Q5TFE4
ALYAQDPSTGCYMYY

KMT5A

301

Q9NQR1
GNYCKYYGYRNPSCE

MEPCE

416

Q7L2J0
PSMTEDYAGRYRCYY

LILRB4

86

Q8NHJ6
DYAGRYRCYYRSPVG

LILRB4

91

Q8NHJ6
DGTTPYCCSYYAYIG

CYYR1

41

Q96J86
YYTHYKCDSPGMCGY

ARSJ

206

Q5FYB0
PGYECYCKQGTYYDP

LTBP1

1446

Q14766
GNCTKYYKGTGYYTC

GLRB

241

P48167
PSTVYDSAGRYRCYY

LILRB5

86

O75023
YSYRCDYYNDCGDGS

LRP2

2756

P98164
PYKRGFYCGDDSIRY

PLPP2

31

O43688
GTYRCYGSFNDSPYK

KIR3DX1

291

Q9H7L2
PEDEAEYYCLLYYGG

IGLV7-43

101

P04211
VGNYTCYADGYEQVY

FSTL5

316

Q8N475
QYTYGYEYLGACPRL

DNAH6

1431

Q9C0G6
PDCYYSIGRENYNQY

CPM

136

P14384
EECRGYYYVYKDGDP

CACNA1S

966

Q13698
PGEEYTCGTNFAYYY

CACNA1S

1346

Q13698
GYECYCKQGFYYDGN

LTBP3

1016

Q9NS15
LGYGYDCKYSYTSGF

KRTAP20-3

11

Q3LI60
NYYGSLDYGCSYGSE

KRTAP22-2

6

Q3LI68
DDVGYYSCSLYTYPQ

CD226

101

Q15762
VNYKGYFKCECYPGY

LRP8

391

Q14114
CPEGTNAYRSYCYYF

REG1A

36

P05451
CPEGTNAYRSYCYYF

REG1B

36

P48304
YQIRVTCDDYYYGFG

JAG1

181

P78504
YCGKPYTYAYGLGLN

RPE65

426

Q16518
YYVCYKCRKAYFGGE

MYCBP2

4541

O75592
LQGYRYYDPKTCGFD

GOT2

176

P00505
SEYPEKYYPDYCSGE

B3GALT9

231

A8MXE2
SDYAKYYALVCYGPG

FAP

456

Q12884
YYGEYYNAPLKRGSD

SUSD1

676

Q6UWL2
PYECKECGKGFYYSY

ZNF80

216

P51504
YECFGGEYRPKVYDQ

USP24

2006

Q9UPU5
TPYEGNYYKCSDYGR

ZNF484

321

Q5JVG2