Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ADAM_spacer1	ADAMTS17 ADAMTS15	1.33e-03	23	44	2	IPR010294
Domain	ADAM_spacer1	ADAMTS17 ADAMTS15	1.33e-03	23	44	2	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS17 ADAMTS15	1.45e-03	24	44	2	IPR013273
Domain	ACR	ADAMTS17 ADAMTS15	1.83e-03	27	44	2	SM00608
Domain	ADAM_Cys-rich	ADAMTS17 ADAMTS15	1.83e-03	27	44	2	IPR006586
Domain	Peptidase_M12B_N	ADAMTS17 ADAMTS15	3.80e-03	39	44	2	IPR002870
Domain	Pep_M12B_propep	ADAMTS17 ADAMTS15	3.80e-03	39	44	2	PF01562
Domain	DISINTEGRIN_1	ADAMTS17 ADAMTS15	4.00e-03	40	44	2	PS00427
Domain	Reprolysin	ADAMTS17 ADAMTS15	4.00e-03	40	44	2	PF01421
Domain	ADAM_MEPRO	ADAMTS17 ADAMTS15	4.00e-03	40	44	2	PS50215
Domain	DISINTEGRIN_2	ADAMTS17 ADAMTS15	4.00e-03	40	44	2	PS50214
Domain	Peptidase_M12B	ADAMTS17 ADAMTS15	4.00e-03	40	44	2	IPR001590
Domain	CYSTEINE_SWITCH	ADAMTS17 ADAMTS15	4.20e-03	41	44	2	PS00546
Domain	Disintegrin_dom	ADAMTS17 ADAMTS15	4.20e-03	41	44	2	IPR001762
Domain	Pept_M10_metallopeptidase	ADAMTS17 ADAMTS15	4.61e-03	43	44	2	IPR001818
Domain	TSP_1	ADAMTS17 ADAMTS15	9.67e-03	63	44	2	PF00090
Domain	TSP1	ADAMTS17 ADAMTS15	1.03e-02	65	44	2	SM00209
Domain	TSP1_rpt	ADAMTS17 ADAMTS15	1.03e-02	65	44	2	IPR000884
Domain	TSP1	ADAMTS17 ADAMTS15	1.03e-02	65	44	2	PS50092
Pubmed	Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation.	SFRP2 ZNF844 ZIC5	2.12e-06	20	44	3	12447396
Pubmed	Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.	ZMYM2 ZNFX1 ZHX1	1.55e-05	38	44	3	28680062
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS17 ADAMTS15	3.27e-05	7	44	2	11867212
Pubmed	Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities.	FOXM1 CDON	1.21e-04	13	44	2	30705426
Pubmed	Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion.	FOXM1 CCNG1	1.41e-04	14	44	2	36012294
Pubmed	A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development.	CDON PCNT	1.41e-04	14	44	2	25191221
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ARHGAP32 USF3 GSPT2 ZHX1 PCNT	2.06e-04	430	44	5	35044719
Pubmed	Specification of SUMO1- and SUMO2-interacting motifs.	ZMYM2 ZHX1	3.56e-04	22	44	2	16524884
Pubmed	A human MAP kinase interactome.	ZMYM2 ARHGAP32 USF3 ZHX1 HERPUD1	3.62e-04	486	44	5	20936779
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FOXM1 ZMYM2 FASN ZHX1 USP19 ZFX	4.09e-04	774	44	6	15302935
Pubmed	Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages.	ZNF844 FBXL3	7.57e-04	32	44	2	26142281
Pubmed	Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.	FASN HERPUD1	8.06e-04	33	44	2	27416896
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXM1 ZNFX1 USF3 EZH1 ZHX1 ZFX	9.43e-04	908	44	6	19274049
Pubmed	O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development.	ADAMTS17 HERPUD1	9.59e-04	36	44	2	35167946
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ZMYM2 ARHGAP32 ZNFX1 PREX1 AHNAK2	1.23e-03	638	44	5	31182584
Pubmed	Individual retinal progenitor cells display extensive heterogeneity of gene expression.	FOXM1 SFRP2	1.24e-03	41	44	2	18270576
Cytoband	11q25	ADAMTS15 JAM3	2.88e-04	26	44	2	11q25
Cytoband	20q13.13	ZNFX1 PREX1	4.37e-04	32	44	2	20q13.13
Cytoband	Ensembl 112 genes in cytogenetic band chr11q24	ADAMTS15 ARHGAP32 CDON	8.28e-04	191	44	3	chr11q24
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS17 ADAMTS15	5.09e-04	19	32	2	50
Coexpression	ZHOU_INFLAMMATORY_RESPONSE_LPS_UP	NCOA7 ZNFX1 USF3 RTP4 ZFX CDON AHNAK2	2.90e-06	406	41	7	M9673
Coexpression	GSE37532_WT_VS_PPARG_KO_LN_TCONV_UP	ZMYM2 NCOA7 DGCR8 INPP5F AHNAK2	1.47e-05	200	41	5	M8954
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_7DY_DN	ZMYM2 ZNFX1 USF3 TRIM13 ZNF844 HERPUD1 USP19 ZFX	4.16e-05	844	41	8	M41129
Disease	sensory peripheral neuropathy, remission	FOXM1 DLEC1	5.39e-04	23	44	2	EFO_0009785, MONDO_0002321
Disease	gas trapping measurement	DLEC1 MRPL14	8.60e-04	29	44	2	EFO_0007628
Disease	hepatocellular carcinoma (implicated_via_orthology)	FOXM1 CCNG1	2.44e-03	49	44	2	DOID:684 (implicated_via_orthology)
Disease	body surface area	ADAMTS17 NCOA7 DLEC1 CPNE4 ZNF844	2.60e-03	643	44	5	EFO_0022196
Disease	macula measurement	ARHGAP32 SFRP2 INVS	2.82e-03	189	44	3	EFO_0008375
Disease	polyp of colon	XRRA1 PREX1	3.18e-03	56	44	2	MONDO_0021400
Disease	urate measurement, spine bone mineral density	CPNE4 C1orf141	3.41e-03	58	44	2	EFO_0004531, EFO_0007701
Disease	Intellectual Disability	ZMYM2 FASN VPS53 FBXL3	4.37e-03	447	44	4	C3714756
Disease	stem Cell Factor measurement	HERPUD1 AHNAK2	4.52e-03	67	44	2	EFO_0008291
Disease	Nonorganic psychosis	DGCR8 PCNT	4.78e-03	69	44	2	C0349204

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKMHVSFKCEPEPRK	C1orf141	76	Q5JVX7
PLSSIPCLHYKKMKD	DGCR8	346	Q8WYQ5
CPLVLPVKHSKMQKP	C2orf73	111	Q8N5S3
PVKHSKMQKPSCGIV	C2orf73	116	Q8N5S3
SCKKVTGLFTKPMHG	ADAMTS15	681	Q8TE58
KISAKGPTKLPLHLM	ADAMTS17	751	Q8TE56
LCISKVPPGTKHVDM	INTS8	116	Q75QN2
VLHLVCNVKSPSKMP	HERPUD1	81	Q15011
KMKVQPKHLGCVGLS	CCNG1	86	P51959
LFMRCLKPNHKKEPG	MYO15A	1791	Q9UKN7
TKQMVDCSHYKKLPP	SPINK9	26	Q5DT21
KGMCTSPPLIKHGVI	F13B	521	P05160
KVGFSPKKDIHFMPC	GSPT2	376	Q8IYD1
VPKAVPVGKMATLHC	JAM3	146	Q9BX67
KLPFTKGHFPKMAEC	ARHGAP32	106	A7KAX9
LPDSTSKKSCHPMIK	PCNT	3321	O95613
KLLKMSSCPHVSPAG	FBXL3	201	Q9UKT7
LSKPDPCVILKMQSH	CPNE4	41	Q96A23
GLEMKPLSHVKVPVC	CDON	1146	Q4KMG0
LKSHLPYCKMIGPTI	C17orf80	21	Q9BSJ5
CKFPAGIKIINHPTM	FOXM1	56	Q08050
KPSCTIIPLMKKDHR	FASN	776	P49327
LPCHVSGMKKPLVLG	DLEC1	1051	Q9Y238
PTLFGKPKFSCMRLH	INPP5F	681	Q9Y2H2
KSKLPHICGFPIKMT	C18orf63	296	Q68DL7
SPKCLALLLKFMAPG	INVS	126	Q9Y283
LKSCMTKPSKSLLPH	RTP4	166	Q96DX8
PLVMKQCHPDTKKFL	SFRP2	81	Q96HF1
KKKALIVGHCMPGPR	MRPL14	81	Q6P1L8
KSKTPPMFLCIKVGK	NCOA7	651	Q8NI08
ELCRLMKSFVHPKPG	PREX1	1541	Q8TCU6
GLKGHLPKVQMPCLK	AHNAK2	4211	Q8IVF2
KGSLLHLTLPKKVPM	USP19	181	O94966
KISPKMPVCKGHLGQ	TRIM13	86	O60858
HQLALKLPPCTDMKS	TEX52	61	A6NCN8
MKPVSGHPFLKKCTI	EZH1	71	Q92800
TGKICKKTPEQLHML	ZHX1	661	Q9UKY1
KVLKKMTPCVTNIPH	USF3	291	Q68DE3
PKFITHLFKCKPISM	VPS53	676	Q5VIR6
MVTIKLKCGHSQPVK	ZNFX1	1401	Q9P2E3
KPSHLPHTFKCMKGL	ZNF844	511	Q08AG5
SSFSHKPAPKKLCVM	ZMYM2	361	Q9UBW7
PASMPLKSKKAFGIC	ZSWIM3	446	Q96MP5
PLTVYPCMICGKKFK	ZFX	421	P17010
MLKHPLLCHSSKPKL	XRRA1	646	Q6P2D8
TKMEKHPQKLPKCVP	TGFBR3	711	Q03167
SSLRKHMKIHCKSPP	ZIC5	566	Q96T25