Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprostaglandin J receptor activity

PTGDR PTGDR2

5.46e-0521482GO:0001785
GeneOntologyMolecularFunctionprostaglandin D receptor activity

PTGDR PTGDR2

5.46e-0521482GO:0004956
GeneOntologyMolecularFunctionRNA polymerase II activity

POLR2J3 POLR2J POLR2J2

6.30e-05111483GO:0001055
GeneOntologyMolecularFunctioncalmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity

PDE1A PDE1C

1.63e-0431482GO:0048101
GeneOntologyMolecularFunctioncalmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity

PDE1A PDE1C

1.63e-0431482GO:0004117
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2

3.24e-0441482GO:0005219
GeneOntologyMolecularFunction3',5'-cyclic-AMP phosphodiesterase activity

PDE1A PDE1C PDE3B

5.54e-04221483GO:0004115
GeneOntologyMolecularFunction3',5'-cyclic-GMP phosphodiesterase activity

PDE1A PDE1C PDE3B

7.20e-04241483GO:0047555
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2

8.03e-0461482GO:0048763
GeneOntologyMolecularFunction3',5'-cyclic-nucleotide phosphodiesterase activity

PDE1A PDE1C PDE3B

8.14e-04251483GO:0004114
GeneOntologyMolecularFunctioncyclic-nucleotide phosphodiesterase activity

PDE1A PDE1C PDE3B

1.02e-03271483GO:0004112
GeneOntologyMolecularFunctionDNA-directed 5'-3' RNA polymerase activity

POLR2J3 POLR2J POLR2J2

1.40e-03301483GO:0003899
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

ACAP1 PSD RASGRF1 TBC1D2B ALS2CL SYNGAP1 RGS14 NF1 NGEF DEPDC1B SOS2

1.43e-0350714811GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

ACAP1 PSD RASGRF1 TBC1D2B ALS2CL SYNGAP1 RGS14 NF1 NGEF DEPDC1B SOS2

1.43e-0350714811GO:0030695
GeneOntologyMolecularFunctioncalmodulin binding

PDE1A PDE1C MYLK RYR1 RYR2 MYH14 KCNN1

1.66e-032301487GO:0005516
GeneOntologyMolecularFunction5'-3' RNA polymerase activity

POLR2J3 POLR2J POLR2J2

1.69e-03321483GO:0034062
GeneOntologyMolecularFunctionRNA polymerase activity

POLR2J3 POLR2J POLR2J2

1.69e-03321483GO:0097747
GeneOntologyCellularComponentcell division site

SPIRE2 PSD MYLK MAEA PSTPIP1 PKN1 PKN2

1.52e-06801477GO:0032153
GeneOntologyCellularComponentcleavage furrow

SPIRE2 PSD MYLK PSTPIP1 PKN1 PKN2

4.41e-06611476GO:0032154
GeneOntologyCellularComponentplasma membrane proton-transporting V-type ATPase complex

ATP6V0D1 ATP6V0D2

4.91e-0521472GO:0033181
GeneOntologyCellularComponentstereocilium

CDH23 ADGRV1 ADCY6 LOXHD1 USH2A

1.26e-04691475GO:0032420
GeneOntologyCellularComponentspot adherens junction

DSG3 PKP3

1.47e-0431472GO:0005914
GeneOntologyCellularComponentcilium

PDE1A PDE1C EVC2 CNTRL PCDHB13 PCDHB8 CDH23 ADGRV1 QRICH2 ADCY6 RSPH10B2 AKAP9 CATSPER2 DNAI4 CFAP57 USH2A RSPH10B

1.98e-0489814717GO:0005929
GeneOntologyCellularComponentRNA polymerase II, core complex

POLR2J3 POLR2J POLR2J2

2.16e-04171473GO:0005665
GeneOntologyCellularComponentcell leading edge

PSD MYLK CARMIL1 ADGRV1 PSTPIP1 CDC42BPB PTPRM SYNE2 MACF1 PKN2 USH2A WWC1

2.22e-0450014712GO:0031252
GeneOntologyCellularComponentstereocilium bundle

CDH23 ADGRV1 ADCY6 LOXHD1 USH2A

2.38e-04791475GO:0032421
GeneOntologyCellularComponentUSH2 complex

ADGRV1 USH2A

2.92e-0441472GO:1990696
GeneOntologyCellularComponentphotoreceptor connecting cilium

PCDHB13 PCDHB8 ADGRV1 USH2A

3.59e-04481474GO:0032391
GeneOntologyCellularComponentstereocilia ankle link

ADGRV1 USH2A

7.23e-0461472GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

ADGRV1 USH2A

7.23e-0461472GO:0002142
GeneOntologyCellularComponentstereocilium membrane

ADGRV1 USH2A

7.23e-0461472GO:0060171
GeneOntologyCellularComponentpericiliary membrane compartment

ADGRV1 USH2A

7.23e-0461472GO:1990075
GeneOntologyCellularComponentactomyosin contractile ring

MAEA PSTPIP1

1.01e-0371472GO:0005826
GeneOntologyCellularComponenttransmembrane transporter complex

LRRC8E CACNB2 RYR1 RYR2 ATP6V0D1 AKAP9 CATSPER2 KCNJ9 KCNN1 ATP6V0D2 UNC80

1.20e-0352314711GO:1902495
GeneOntologyCellularComponentlamellipodium

MYLK CARMIL1 PSTPIP1 CDC42BPB PTPRM SYNE2 PKN2

1.23e-032301477GO:0030027
GeneOntologyCellularComponentstereocilia coupling link

ADGRV1 USH2A

1.34e-0381472GO:0002139
GeneOntologyCellularComponentcation channel complex

CACNB2 RYR1 RYR2 AKAP9 CATSPER2 KCNN1 UNC80

1.40e-032351477GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

LRRC8E CACNB2 RYR1 RYR2 AKAP9 CATSPER2 KCNJ9 KCNN1 UNC80

1.45e-033781479GO:0034702
GeneOntologyCellularComponent9+2 motile cilium

PDE1A QRICH2 RSPH10B2 AKAP9 CATSPER2 CFAP57 RSPH10B

1.50e-032381477GO:0097729
GeneOntologyCellularComponentcalcium channel complex

CACNB2 RYR1 RYR2 CATSPER2

1.75e-03731474GO:0034704
GeneOntologyCellularComponenttransporter complex

LRRC8E CACNB2 RYR1 RYR2 ATP6V0D1 AKAP9 CATSPER2 KCNJ9 KCNN1 ATP6V0D2 UNC80

1.79e-0355014711GO:1990351
GeneOntologyCellularComponentmicrotubule organizing center

TCP1 CNTRL CDH23 CCDC141 RGS14 CCDC13 ATP6V0D1 AKAP9 CROCC2 NINL CKAP2L PKN2 MPHOSPH9 USH2A HTT

2.10e-0391914715GO:0005815
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

RYR1 RYR2

2.13e-03101472GO:0014701
GeneOntologyCellularComponentperinuclear region of cytoplasm

GAD1 CNTRL ADGRV1 UNC45A PSTPIP1 CMYA5 RYR1 PTPRM SEC16A ROS1 PKN2 EIF3G CALN1 WWC1 HTT

2.45e-0393414715GO:0048471
GeneOntologyCellularComponentciliary transition zone

PCDHB13 PCDHB8 ADGRV1 USH2A

2.57e-03811474GO:0035869
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRT12 EPPK1 KRT33B KRT24 SYNE2 MACF1 PKN2

2.64e-032631477GO:0045111
GeneOntologyCellularComponentproton-transporting V-type ATPase, V0 domain

ATP6V0D1 ATP6V0D2

3.10e-03121472GO:0033179
GeneOntologyCellularComponentcentrosome

TCP1 CNTRL CDH23 CCDC141 RGS14 CCDC13 ATP6V0D1 AKAP9 CROCC2 NINL CKAP2L PKN2 MPHOSPH9

3.12e-0377014713GO:0005813
GeneOntologyCellularComponentmitotic spindle pole

CNTRL RMDN3 FAM83D

3.42e-03431473GO:0097431
GeneOntologyCellularComponentsarcoplasmic reticulum

CMYA5 RYR1 RYR2 SYNE2

3.47e-03881474GO:0016529
GeneOntologyCellularComponentmotile cilium

PDE1A QRICH2 RSPH10B2 AKAP9 CATSPER2 DNAI4 CFAP57 RSPH10B

3.70e-033551478GO:0031514
GeneOntologyCellularComponentleading edge membrane

PSD ADGRV1 SYNE2 MACF1 USH2A WWC1

3.75e-032101476GO:0031256
GeneOntologyCellularComponentsupramolecular fiber

KRT12 EPPK1 TCP1 KRT33B CARMIL1 PSTPIP1 CMYA5 RYR1 RYR2 RMDN3 RGS14 KRT24 MYH14 SYNE2 NINL MACF1 JAKMIP1

3.88e-03117914717GO:0099512
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR1 RYR2 SYNE2

3.90e-03451473GO:0033017
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNB2 RYR1 CATSPER2

4.15e-03461473GO:0005891
GeneOntologyCellularComponentsupramolecular polymer

KRT12 EPPK1 TCP1 KRT33B CARMIL1 PSTPIP1 CMYA5 RYR1 RYR2 RMDN3 RGS14 KRT24 MYH14 SYNE2 NINL MACF1 JAKMIP1

4.15e-03118714717GO:0099081
GeneOntologyCellularComponentcontractile ring

MAEA PSTPIP1

4.23e-03141472GO:0070938
GeneOntologyCellularComponentcluster of actin-based cell projections

CDH23 ADGRV1 ADCY6 LOXHD1 MYH14 USH2A

5.01e-032231476GO:0098862
DomainRNA_POL_L_13KD

POLR2J3 POLR2J POLR2J2

1.82e-0641453PS01154
DomainRNA_pol_Rpb11_13-16kDa_CS

POLR2J3 POLR2J POLR2J2

1.82e-0641453IPR008193
DomainRBP11-like_dimer

POLR2J3 POLR2J POLR2J2

9.01e-0661453IPR009025
DomainRNA_pol_L

POLR2J3 POLR2J POLR2J2

9.01e-0661453PF01193
DomainHECW_N

HECW1 HECW2

5.99e-0521452IPR032348
DomainvATP-synt_AC39

ATP6V0D1 ATP6V0D2

5.99e-0521452PF01992
DomainATPase_V0-cplx_dsu

ATP6V0D1 ATP6V0D2

5.99e-0521452IPR016727
DomainHECW_N

HECW1 HECW2

5.99e-0521452PF16562
DomainATPase_V0-cplx_csu/dsu

ATP6V0D1 ATP6V0D2

5.99e-0521452IPR002843
DomainRyanodine_rcpt

RYR1 RYR2

1.79e-0431452IPR003032
DomainRyanrecept_TM4-6

RYR1 RYR2

1.79e-0431452IPR009460
DomainRNA_pol_L_2

POLR2J POLR2J2

1.79e-0431452PF13656
DomainPDEase_N

PDE1A PDE1C

1.79e-0431452IPR013706
DomainPDEase_I_N

PDE1A PDE1C

1.79e-0431452PF08499
DomainRyR

RYR1 RYR2

1.79e-0431452PF02026
DomainRR_TM4-6

RYR1 RYR2

1.79e-0431452PF06459
DomainRyan_recept

RYR1 RYR2

1.79e-0431452IPR013333
DomainARM-type_fold

USP34 ZBTB7C XPO1 UNC45A PPP4R4 NF1 PKP3 EFR3B HTT SYMPK

3.22e-0433914510IPR016024
Domain-

XPO1 UNC45A PPP4R4 NF1 PKP3 EFR3B HTT SYMPK

3.47e-0422214581.25.10.10
DomainPH

ACAP1 PSD RASGRF1 TBC1D2B CDC42BPB SYNGAP1 NGEF SOS2

4.27e-042291458PF00169
DomainWW

HECW1 PRPF40B HECW2 WWC1

4.80e-04471454PF00397
DomainWW

HECW1 PRPF40B HECW2 WWC1

5.20e-04481454SM00456
DomainPDEase_I

PDE1A PDE1C PDE3B

5.50e-04211453PF00233
DomainPDEASE_I

PDE1A PDE1C PDE3B

5.50e-04211453PS00126
DomainPDEase_CS

PDE1A PDE1C PDE3B

5.50e-04211453IPR023174
Domain-

PKN1 PKN2

5.89e-04514521.10.287.160
Domain-

PDE1A PDE1C PDE3B

6.33e-042214531.10.1300.10
DomainWW_DOMAIN_1

HECW1 PRPF40B HECW2 WWC1

6.56e-04511454PS01159
DomainWW_DOMAIN_2

HECW1 PRPF40B HECW2 WWC1

6.56e-04511454PS50020
DomainWW_dom

HECW1 PRPF40B HECW2 WWC1

7.07e-04521454IPR001202
DomainSpectrin

CCDC141 SYNE2 MACF1

7.24e-04231453PF00435
DomainPDEase_catalytic_dom

PDE1A PDE1C PDE3B

7.24e-04231453IPR002073
DomainHD/PDEase_dom

PDE1A PDE1C PDE3B

8.23e-04241453IPR003607
DomainHDc

PDE1A PDE1C PDE3B

8.23e-04241453SM00471
DomainC2

HECW1 SYNGAP1 HECW2 PKN1 PKN2 WWC1

8.50e-041421456PS50004
DomainRIH_assoc-dom

RYR1 RYR2

8.80e-0461452IPR013662
Domain-

EPPK1 MACF1

8.80e-04614523.90.1290.10
DomainIns145_P3_rec

RYR1 RYR2

8.80e-0461452PF08709
DomainRIH_assoc

RYR1 RYR2

8.80e-0461452PF08454
DomainRIH_dom

RYR1 RYR2

8.80e-0461452IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2

8.80e-0461452IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2

8.80e-0461452IPR015925
Domain-

RYR1 RYR2

8.80e-04614521.25.10.30
DomainRYDR_ITPR

RYR1 RYR2

8.80e-0461452PF01365
Domain-

HECW1 SYNGAP1 HECW2 PKN1 PKN2 WWC1

1.05e-0314814562.60.40.150
DomainHr1

PKN1 PKN2

1.23e-0371452SM00742
DomainPlectin

EPPK1 MACF1

1.23e-0371452PF00681
DomainPlectin_repeat

EPPK1 MACF1

1.23e-0371452IPR001101
DomainPLEC

EPPK1 MACF1

1.23e-0371452SM00250
DomainARM-like

XPO1 UNC45A PPP4R4 NF1 PKP3 EFR3B HTT SYMPK

1.25e-032701458IPR011989
DomainSpectrin_repeat

CCDC141 SYNE2 MACF1

1.44e-03291453IPR002017
DomainPH

ACAP1 PSD RASGRF1 TBC1D2B CDC42BPB SYNGAP1 NGEF SOS2

1.50e-032781458SM00233
DomainPH_DOMAIN

ACAP1 PSD RASGRF1 TBC1D2B CDC42BPB SYNGAP1 NGEF SOS2

1.53e-032791458PS50003
DomainPH_domain

ACAP1 PSD RASGRF1 TBC1D2B CDC42BPB SYNGAP1 NGEF SOS2

1.57e-032801458IPR001849
DomainAH/BAR-dom

ACAP1 KRT12 SH3GLB2

1.60e-03301453IPR027267
Domain-

ACAP1 KRT12 SH3GLB2

1.60e-033014531.20.1270.60
DomainU-box

RNF151 UBE4A

1.63e-0381452PF04564
DomainHR1

PKN1 PKN2

1.63e-0381452PF02185
DomainConA-like_dom

ADGRV1 CMYA5 SVEP1 RYR1 RYR2 PTPRM USH2A

1.63e-032191457IPR013320
DomainC2_dom

HECW1 SYNGAP1 HECW2 PKN1 PKN2 WWC1

1.78e-031641456IPR000008
Domain-

RASGRF1 ALS2CL NGEF SOS2

2.26e-037114541.20.900.10
DomainDH-domain

RASGRF1 ALS2CL NGEF SOS2

2.26e-03711454IPR000219
DomainPrefoldin

RB1CC1 KRT24 MPHOSPH9 CFAP57

2.38e-03721454IPR009053
DomainMIR

RYR1 RYR2

2.59e-03101452PF02815
DomainUbox_domain

RNF151 UBE4A

2.59e-03101452IPR003613
DomainMIR_motif

RYR1 RYR2

2.59e-03101452IPR016093
DomainMIR

RYR1 RYR2

2.59e-03101452PS50919
DomainMIR

RYR1 RYR2

2.59e-03101452SM00472
DomainPkinase_C

CDC42BPB PKN1 PKN2

2.94e-03371453IPR017892
DomainGDS_CDC24_CS

RASGRF1 NGEF SOS2

3.41e-03391453IPR001331
DomainPkinase_C

CDC42BPB PKN1 PKN2

4.22e-03421453PF00433
DomainC2

HECW1 SYNGAP1 HECW2 PKN1 PKN2

4.33e-031371455SM00239
DomainKeratin_I

KRT12 KRT33B KRT24

4.81e-03441453IPR002957
DomainRasGAP

SYNGAP1 NF1

5.12e-03141452SM00323
DomainRas_G-nucl-exch_fac_CS

RASGRF1 SOS2

5.12e-03141452IPR019804
DomainMORN

ALS2CL RSPH10B

5.12e-03141452SM00698
DomainRasGAP_CS

SYNGAP1 NF1

5.12e-03141452IPR023152
DomainMORN

ALS2CL RSPH10B

5.88e-03151452IPR003409
DomainRasGAP

SYNGAP1 NF1

5.88e-03151452PF00616
DomainRAS_GTPASE_ACTIV_1

SYNGAP1 NF1

5.88e-03151452PS00509
DomainMORN

ALS2CL RSPH10B

5.88e-03151452PF02493
DomainRAS_GTPASE_ACTIV_2

SYNGAP1 NF1

5.88e-03151452PS50018
DomainSH3

CACNB2 SH3GLB2 NCF4 PSTPIP1 NGEF MACF1

6.86e-032161456PS50002
DomainSH3_domain

CACNB2 SH3GLB2 NCF4 PSTPIP1 NGEF MACF1

7.48e-032201456IPR001452
PathwayWP_RETT_SYNDROME

TAF1B XAB2 SYNGAP1 SYNE2 HTT

3.61e-05481115M39759
PathwayKEGG_PURINE_METABOLISM

AMPD2 PDE1A PDE1C PDE3B POLR2J3 POLR2J ADCY6 POLR2J2

3.63e-051591118M14314
PathwayPID_RAS_PATHWAY

RASGRF1 SYNGAP1 NF1 SOS2

8.52e-05301114M269
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 HECW1 ADGRV1 PHF8 CDC42BPB ADCY6 SYNE2 SEC16A MACF1 ERC2 UNC80

4.40e-092251501112168954
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX16 USP34 RBM15 EPPK1 XPO1 XAB2 LARP7 FASN NF1 MYH14 SYNE2 DDX54 SEC16A GEMIN4 MACF1 SYMPK

2.66e-086531501622586326
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

RBM15 EPPK1 ZBTB7C ATRX TCP1 UNC45A FANCD2 FASN NF1 PKP3 GEMIN4 MACF1 PKN2 CLP1 SYMPK

3.85e-085821501520467437
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNB2 AMPD2 HECW1 PHB2 CDC42BPB SYNGAP1 CCDC13 NF1 AKAP9 SYNE2 SEC16A NGEF ZSCAN18 MACF1 ERC2 PKN1 JAKMIP1 TMED10

2.02e-079631501828671696
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DHX16 RBM15 ATRX CARMIL1 XPO1 PHF8 ADCY6 FANCD2 FASN NF1 PKP3 SEC16A PKN1 PKN2 EIF3G SYMPK

2.67e-077741501615302935
Pubmed

[New genes on human chromosome 7: bioinformatic analysis of a gene cluster from the POLR2J family].

POLR2J3 POLR2J POLR2J2

3.14e-074150315586814
Pubmed

A human RNA polymerase II subunit is encoded by a recently generated multigene family.

POLR2J3 POLR2J POLR2J2

3.14e-074150311747469
Pubmed

Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina.

ADGRV1 ADCY6 USH2A

3.14e-074150337127773
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CYP4V2 CACNB2 PDE3B ATRX POLR2J3 PPFIA2 CARMIL1 MAEA ASH1L ADGRV1 CDC42BPB PPP4R4 ZNF827 MYH14 PKP3 NGEF POLR2J2 CDK5RAP1 MACF1 PKN1 HTT SOS2

4.66e-0714891502228611215
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

TCP1 CARMIL1 PHB2 SRPRA XPO1 UNC45A FASN SEC16A EFR3B GEMIN4 MACF1 PKN2 MPHOSPH9 EIF3G DEPDC1B

4.74e-077081501539231216
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

CDH23 ADGRV1 ADCY6 USH2A

5.81e-0716150417567809
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RBM15 TCP1 SRPRA XPO1 RB1CC1 PHF8 CDC42BPB PPP4R4 FANCD2 VIPAS39 AKAP9 PTPRM SYNE2 DDX54 SEC16A EFR3B MPHOSPH9 SYMPK

6.97e-0710491501827880917
Pubmed

The thymocyte-specific MAR binding protein, SATB1, interacts in vitro with a novel variant of DNA-directed RNA polymerase II, subunit 11.

POLR2J3 POLR2J POLR2J2

7.81e-075150312036295
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KRT12 MYLK ATRX KRT33B PPFIA2 TAF1B CNTRL ASH1L PHB2 TWNK ADCY6 RYR2 LARP7 PPP4R4 RGS14 FASN MYH14 SYNE2 MACF1 ERC2 JAKMIP1

1.10e-0614421502135575683
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PDE3B MRS2 BMP2K TCP1 PHB2 SH3GLB2 TWNK SRPRA GFM2 FANCD2 RMDN3 UBE4A VIPAS39 AKAP9 SYNE2 DDX54 SEC16A GEMIN4 CDK5RAP1 TMED10 DEPDC1B

1.97e-0614961502132877691
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

DHX16 USP34 RBM15 RNMT ATRX TCP1 PHB2 XPO1 UNC45A PHF8 XAB2 LARP7 FANCD2 FASN EIF3G CDCA7L SYMPK

1.99e-0610141501732416067
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

DHX16 RBM15 EPPK1 TCP1 KRT33B XPO1 RB1CC1 XAB2 FASN NF1 MYH14 PKP3 SYNE2 DDX54 SEC16A CKAP2L MACF1

2.27e-0610241501724711643
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

KRT12 BMP2K TCP1 KRT33B FASN KRT24 MYH14 SEC16A SOS2

2.54e-06266150919380743
Pubmed

Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.

CDH23 ADGRV1 USH2A

2.72e-067150320058854
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

AMPD2 EPPK1 TCP1 CARMIL1 POLR2J PHB2 PNO1 SRPRA XPO1 UNC45A XAB2 FASN PKP3 SYNE2 DDX54 SEC16A GEMIN4 MACF1 PKN2 EIF3G

3.19e-0614151502028515276
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

AMPD2 PDE3B EPPK1 RNMT MRS2 MAEA POLR2J PHB2 TWNK SRR PHF8 ATP6V0D1

3.78e-065331501225544563
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

GALNTL6 PDE3B TCP1 PPFIA2 SRPRA PHF8 QRICH2 RYR1 LOXHD1 HECW2 KCNJ9 JAKMIP1 CFAP57 SYMPK

4.05e-067361501429676528
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

AMPD2 RBM15 SH3GLB2 SRPRA VIPAS39 NF1 AKAP9 SEC16A NINL MPHOSPH9 WWC1

4.11e-064461501124255178
Pubmed

Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.

CDH23 ADGRV1 USH2A

4.33e-068150319683999
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

CYP4V2 PPFIA2 TBC1D2B CARD8 RYR1 FASN DNAI4 PKN1

4.48e-06214150822199357
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

RNMT TCP1 TAF1B XPO1 RB1CC1 XAB2 NF1 DDX54 SEC16A TMED10 CLP1

4.87e-064541501133226137
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

AMPD2 RBM15 PDE3B SPIRE2 CARMIL1 UNC45A CARD8 PPP4R4 NF1 AKAP9 SYNE2 SEC16A MACF1 MPHOSPH9 DEPDC1B

5.22e-068611501536931259
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

PDE3B ATRX MRS2 PHB2 TWNK SRPRA UNC45A RB1CC1 CDC42BPB LARP7 UBE4A AKAP9 SYNE2 DDX54 EFR3B CDK5RAP1 MACF1 PKN2 TMED10 DEPDC1B

6.66e-0614871502033957083
Pubmed

Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.

CDH23 ADGRV1 USH2A

9.23e-0610150324618850
Pubmed

Usher protein functions in hair cells and photoreceptors.

CDH23 ADGRV1 USH2A

9.23e-0610150324239741
Pubmed

Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.

GAD1 PCDHB13 PCDHB8

9.23e-0610150322969705
Pubmed

A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.

CDH23 ADGRV1 LOXHD1

9.23e-0610150317329413
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

RBM15 EPPK1 MYLK TCP1 PHB2 SRPRA XPO1 GFM2 FASN MYH14 PKP3 DDX54 MACF1

1.38e-057111501333022573
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

USP34 BMP2K TCP1 MAEA PHB2 SRPRA XPO1 UNC45A GFM2 LARP7 FANCD2 UBE4A FASN ATP6V0D1 SYNE2 DDX54 GEMIN4 EIF3G TMED10

1.51e-0514401501930833792
Pubmed

Distinct regions of RPB11 are required for heterodimerization with RPB3 in human and yeast RNA polymerase II.

POLR2J3 POLR2J2

1.85e-052150215987790
Pubmed

Expression, purification and characterization of human vacuolar-type H(+)-ATPase subunit d1 and d2 in Escherichia coli.

ATP6V0D1 ATP6V0D2

1.85e-052150224631925
Pubmed

Lipopolysaccharide induces proinflammatory cytokines and chemokines in experimental otitis media through the prostaglandin D2 receptor (DP)-dependent pathway.

PTGDR PTGDR2

1.85e-052150221166666
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

1.85e-052150217259277
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

1.85e-052150214722100
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

1.85e-052150226009179
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

1.85e-052150232899693
Pubmed

Novel roles of PRK1 and PRK2 in cilia and cancer biology.

PKN1 PKN2

1.85e-052150232127582
Pubmed

Stage and cell-specific expression of calmodulin-dependent phosphodiesterases in mouse testis.

PDE1A PDE1C

1.85e-052150211369604
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

1.85e-052150215033925
Pubmed

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells.

CDH23 USH2A

1.85e-052150217360538
Pubmed

The opposing role of two prostaglandin D2 receptors, DP and CRTH2, in human eosinophil migration.

PTGDR PTGDR2

1.85e-052150221624751
Pubmed

Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease.

RYR2 HTT

1.85e-052150232897880
Pubmed

Role of prostaglandin D2 receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivo.

PTGDR PTGDR2

1.85e-052150219060214
Pubmed

Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.

ADGRV1 USH2A

1.85e-052150215671307
Pubmed

CAMDI interacts with the human memory-associated protein KIBRA and regulates AMPAR cell surface expression and cognition.

CCDC141 WWC1

1.85e-052150231730661
Pubmed

Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.

ADGRV1 USH2A

1.85e-052150234638692
Pubmed

Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans.

PTGDR PTGDR2

1.85e-052150216617107
Pubmed

Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation.

PTGDR PTGDR2

1.85e-052150224298012
Pubmed

Possible novel receptor for PGD2 on human bronchial epithelial cells.

PTGDR PTGDR2

1.85e-052150217541272
Pubmed

Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.

ADGRV1 USH2A

1.85e-052150228653555
Pubmed

Protein kinase C-related kinase 1 and 2 play an essential role in thromboxane-mediated neoplastic responses in prostate cancer.

PKN1 PKN2

1.85e-052150226296974
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

1.85e-052150230542613
Pubmed

Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family.

PKN1 PKN2

1.85e-05215027851406
Pubmed

Association of a new-type prostaglandin D2 receptor CRTH2 with circulating T helper 2 cells in patients with atopic dermatitis.

PTGDR PTGDR2

1.85e-052150212230502
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

1.85e-052150215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

1.85e-052150211673493
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

1.85e-052150211673462
Pubmed

Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin.

RASGRF1 NF1

1.85e-052150230337665
Pubmed

The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking.

PTGDR PTGDR2

1.85e-052150217878378
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

1.85e-052150225370123
Pubmed

Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation.

LIX1L ROS1

1.85e-052150226310847
Pubmed

Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung.

PTGDR PTGDR2

1.85e-052150226792210
Pubmed

D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells.

PTGDR PTGDR2

1.85e-052150221930295
Pubmed

The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.

CDH23 ADGRV1

1.85e-052150215820310
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

1.85e-052150218618700
Pubmed

Gene structure and functional properties of mouse CRTH2, a prostaglandin D2 receptor.

PTGDR PTGDR2

1.85e-052150212878180
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

TCP1 DSG3 PNO1 TWNK ULBP3 RYR1 LARP7 MYH14 CROCC2 PKP3 CKAP2L TMED10 RSPH10B

1.87e-057321501334732716
Pubmed

Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.

PDE1A PDE1C PDE3B

2.18e-051315038557689
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 MAEA SRPRA XPO1 UNC45A FANCD2 RMDN3 FASN PTPRM PKP3 DDX54 SEC16A GEMIN4 TMED10 WWC1

2.22e-059741501528675297
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LRRC8E USP34 SPIRE2 EPPK1 MAEA TWNK CDC42BPB RYR1 FASN EHBP1L1 ZNF827 SEC16A NINL PKN1 HTT SYMPK

2.47e-0511051501635748872
Pubmed

Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.

PDE1A PDE1C PDE3B

2.76e-0514150325852085
Pubmed

MED12 regulates a transcriptional network of calcium-handling genes in the heart.

RYR1 RYR2 KCNN1

2.76e-0514150328724790
Pubmed

Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.

ASH1L RB1CC1 CDC42BPB

2.76e-0514150328263302
Pubmed

Global landscape of HIV-human protein complexes.

EPPK1 MRS2 PHB2 XPO1 UNC45A LARP7 AKAP9 GEMIN4 EIF3G TMED10

3.17e-054571501022190034
Pubmed

Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.

XPO1 HTT SYMPK

3.44e-0515150311092755
Pubmed

Huntingtin interacts with a family of WW domain proteins.

PRPF40B HTT SYMPK

3.44e-051515039700202
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP34 ATRX ASH1L SH3GLB2 CMYA5 CDC42BPB XAB2 SYNGAP1 UBE4A CCDC13 MYH14 NGEF KCNN1 MACF1 ERC2 JAKMIP1 SOS2

4.24e-0512851501735914814
Pubmed

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.

EPPK1 TCP1 XAB2 SYNGAP1 PKP3

4.57e-0590150535654790
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

ACAP1 EPPK1 TCP1 PHB2 SRPRA UNC45A CDC42BPB FASN KRT24 MYH14 PKP3

4.66e-055801501135676659
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CACNB2 PDE1C TCP1 PPFIA2 CARMIL1 PHB2 XPO1 CDC42BPB SYNGAP1 FASN ATP6V0D1 NF1 MYH14 HECW2 SEC16A NGEF MACF1 ERC2

4.78e-0514311501837142655
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

CDH23 ADGRV1 LRRIQ1 AKAP9 MACF1 HTT

5.38e-05152150634299191
Pubmed

Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis.

PKN1 PKN2

5.53e-053150217332740
Pubmed

High PGD2 receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a zebrafish xenograft model.

PTGDR PTGDR2

5.53e-053150234750492
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2

5.53e-053150218403125
Pubmed

TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease.

TCP1 HTT

5.53e-053150227601642
Pubmed

PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma.

RB1CC1 PHF8

5.53e-053150230180906
Pubmed

Human PMS2 gene family: origin, molecular evolution, and biological implications.

POLR2J3 POLR2J2

5.53e-053150216913423
Pubmed

Arlm1 is a male-specific modifier of astrocytoma resistance on mouse Chr 12.

NF1 CDCA7L

5.53e-053150222234937
Pubmed

CMYA5 establishes cardiac dyad architecture and positioning.

CMYA5 RYR2

5.53e-053150235449169
Pubmed

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.

ADGRV1 USH2A

5.53e-053150220440071
Pubmed

Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis.

PRPF40B HTT

5.53e-053150210958656
Pubmed

Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation.

PKN1 PKN2

5.53e-053150234499618
Pubmed

Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses.

PPFIA2 ERC2

5.53e-053150229439199
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2

5.53e-05315027876312
Pubmed

Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.

RYR1 RYR2

5.53e-053150224123915
InteractionYWHAH interactions

AMPD2 RBM15 PDE3B SPIRE2 EVC2 EPPK1 CARMIL1 CNTRL TWNK XPO1 UNC45A RB1CC1 PPP4R4 SYNGAP1 FANCD2 RMDN3 NF1 AKAP9 SYNE2 SEC16A NINL MACF1 MPHOSPH9 JAKMIP1 DEPDC1B WWC1 HTT

3.49e-08110214927int:YWHAH
InteractionMYO5A interactions

MYLK SYNGAP1 FANCD2 RGS14 LRRIQ1 AKAP9 MYH14 NINL WWC1 FHIP2B HTT

3.56e-0720414911int:MYO5A
InteractionCOPG1 interactions

TCP1 PHB2 XPO1 XAB2 FANCD2 NF1 NGEF GEMIN4 TMED10 DEPDC1B

8.12e-0622914910int:COPG1
InteractionYWHAG interactions

AMPD2 RBM15 PDE3B SPIRE2 KRT33B CARMIL1 XPO1 RB1CC1 PPP4R4 SYNGAP1 FANCD2 RMDN3 NF1 AKAP9 SYNE2 SEC16A NINL MACF1 PKN2 MPHOSPH9 JAKMIP1 DEPDC1B WWC1 HTT

1.51e-05124814924int:YWHAG
InteractionYWHAZ interactions

AMPD2 RBM15 PDE1A PDE3B SPIRE2 RASGRF1 PPFIA2 MAEA SRPRA XPO1 RB1CC1 PPP4R4 SYNGAP1 FANCD2 RMDN3 KRT24 NF1 AKAP9 SYNE2 MACF1 MPHOSPH9 JAKMIP1 DEPDC1B HTT

3.69e-05131914924int:YWHAZ
InteractionCAMSAP2 interactions

XPO1 SYNGAP1 NF1 AKAP9 NINL CKAP2L MACF1 MPHOSPH9

3.78e-051691498int:CAMSAP2
InteractionPOLR2C interactions

TCP1 POLR2J3 CNTRL POLR2J XPO1 PHF8 FANCD2 EHBP1L1 POLR2J2 GEMIN4 CLP1

4.42e-0533814911int:POLR2C
InteractionAURKB interactions

GAD1 EPPK1 TCP1 CNTRL MAEA TBC1D2B ADGRV1 XPO1 CMYA5 FASN MYH14 DDX54 SEC16A GEMIN4 NINL MACF1 UNC80

4.91e-0576114917int:AURKB
InteractionTPTE interactions

PHB2 SRPRA XPO1 UNC45A FANCD2 DDX54 GEMIN4

4.94e-051291497int:TPTE
InteractionNUP155 interactions

PDE3B EVC2 EPPK1 SRPRA XPO1 FANCD2 RMDN3 MYH14 SYNE2 DDX54 SEC16A GEMIN4 MPHOSPH9

5.59e-0547714913int:NUP155
InteractionPDE1A interactions

PDE1A PDE1C HTT

6.26e-05111493int:PDE1A
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2

8.87e-053992287
GeneFamilyFibronectin type III domain containing|USH2 complex

ADGRV1 USH2A

1.77e-0449921244
GeneFamilyPhosphodiesterases

PDE1A PDE1C PDE3B

2.96e-0424993681
GeneFamilyKeratins, type I

KRT12 KRT33B KRT24

4.72e-0428993608
GeneFamilyRNA polymerase subunits

POLR2J3 POLR2J POLR2J2

5.25e-0429993726
GeneFamilyEF-hand domain containing|Plakins

EPPK1 MACF1

8.13e-048992939
GeneFamilyProstaglandin (prostanoid) receptors

PTGDR PTGDR2

1.04e-039992207
GeneFamilyC2 domain containing protein kinases

PKN1 PKN2

1.30e-0310992835
GeneFamilyFibronectin type III domain containing

MYLK CMYA5 PTPRM ROS1 USH2A

1.87e-03160995555
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R21 RB1CC1 RYR1 AKAP9 WWC1

3.19e-03181995694
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF1 NGEF SOS2

5.68e-0366993722
GeneFamilyV-type ATPases

ATP6V0D1 ATP6V0D2

6.97e-0323992415
CoexpressionMIKKELSEN_IPS_ICP_WITH_H3K27ME3

GALNTL6 PDE1C ADCY6 KCNJ9 CFAP57

1.59e-05551505M1970
CoexpressionMIKKELSEN_IPS_ICP_WITH_H3K27ME3

GALNTL6 PDE1C ADCY6 KCNJ9 CFAP57

1.59e-05551505MM842
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 PDE1C HECW1 PPFIA2 ADGRV1 RYR2 LOXHD1 ROS1 USH2A UNC80

7.30e-10184150102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 PDE1C HECW1 PPFIA2 ADGRV1 RYR2 LOXHD1 ROS1 USH2A UNC80

7.30e-1018415010ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 PDE1C HECW1 PPFIA2 ADGRV1 RYR2 LOXHD1 ROS1 USH2A UNC80

7.30e-10184150102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 B4GALNT1 ATRX BMP2K CNTRL ASH1L RB1CC1 SYNE2 PKN2

1.84e-08191150960c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 B4GALNT1 ATRX BMP2K CNTRL ASH1L RB1CC1 SYNE2 PKN2

1.84e-08191150909db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 B4GALNT1 ATRX BMP2K CNTRL ASH1L RB1CC1 SYNE2 PKN2

1.84e-081911509973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 HECW1 RASGRF1 PPFIA2 SIDT1 KCNJ9 ERC2 UBE2QL1 UNC80

2.01e-081931509461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 HECW1 RASGRF1 PPFIA2 SIDT1 KCNJ9 ERC2 UBE2QL1 UNC80

2.01e-0819315090dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 RNMT ATRX ASH1L XPO1 AKAP9 SYNE2 MACF1 PKN2

2.73e-08200150912f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 PDE1A PDE1C FAM153A LOXHD1 ATP6V0D2 UBE2QL1 UNC80

1.47e-07175150898947a226b5a2ac7091ff9d34243ea7736add973
ToppCellRV|World / Chamber and Cluster_Paper

GALNTL6 CACNB2 PDE1A PDE1C CMYA5 CCDC141 AKAP9 PTPRM

1.90e-071811508bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 PDE3B POLR2J3 ASH1L RB1CC1 NF1 SYNE2 MACF1

2.54e-071881508ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 ADGRV1 CCDC141 FASN MYH14 PKP3 ROS1 WWC1

2.64e-0718915086f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 ADGRV1 CCDC141 FASN MYH14 PKP3 ROS1 WWC1

2.64e-071891508926b5fa3064b501a57ba78583e8af33532add455
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PSD HECW1 RASGRF1 RYR2 KCNJ9 ERC2 UBE2QL1 UNC80

2.75e-071901508416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell368C-Epithelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 ADGRV1 CCDC141 FASN MYH14 PKP3 ROS1 WWC1

2.75e-071901508459811e88d3001816c2d89034e0921c24918c17f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 ATRX ASH1L AKAP9 SEC16A MACF1 ERC2 UNC80

3.35e-0719515083e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 ATRX ASH1L AKAP9 SEC16A MACF1 ERC2 UNC80

3.35e-0719515087796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SPIRE2 B4GALNT1 KCNJ9 CKAP2L ATP6V0D2 CFAP57 CDCA7L

8.59e-0715215075ce8920aedd39a4daf7082153b5e213707c14227
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

ACAP1 FBXO36 CCDC141 LRRIQ1 MYH14 SYNE2 RSPH10B

1.02e-06156150710d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 ADGRV1 SVEP1 RYR2 ARL5C USH2A UNC80

1.21e-061601507c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 ADGRV1 SVEP1 RYR2 ARL5C USH2A UNC80

1.21e-06160150725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

EPPK1 CCDC13 LRRIQ1 MYH14 DNAI4 CFAP57 RSPH10B

2.20e-061751507c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 B4GALNT1 SIDT1 PSTPIP1 PKP3 JAKMIP1 CDCA7L

2.29e-06176150727c5ddd67de52101360ef7de8fcfa041066d97db
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 B4GALNT1 SIDT1 PSTPIP1 RGS14 PKP3 JAKMIP1

2.37e-06177150731201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 B4GALNT1 SIDT1 PSTPIP1 RGS14 PKP3 JAKMIP1

2.37e-06177150789d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CACNB2 PDE1A EPPK1 ZBTB7C MYLK PPFIA2 CARMIL1

2.56e-061791507a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellfacs-Heart-RA-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 B4GALNT1 SIDT1 PSTPIP1 RGS14 PKP3 JAKMIP1

2.65e-0618015079be0af61d496a29d737bb772ad09864797994299
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

USP34 ACAP1 PDE3B POLR2J3 ASH1L SYNE2 MACF1

2.75e-061811507f2315414e714ac86211546a935660c4be6e85f1b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNTL6 GAD1 CDH23 SVEP1 PTPRM UBE2QL1 CDCA7L

3.18e-06185150779cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 CACNB2 RGS14 NGEF ERC2 JAKMIP1 CALN1

3.66e-0618915073e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 CACNB2 RGS14 NGEF ERC2 JAKMIP1 CALN1

3.66e-061891507851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 CACNB2 RGS14 NGEF ERC2 JAKMIP1 CALN1

3.79e-0619015071c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

RASGRF1 ADGRV1 CCDC141 FASN MYH14 ROS1 WWC1

3.79e-06190150727a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell367C-Epithelial_cells|367C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 FASN LRRIQ1 MYH14 PKP3 ROS1 WWC1

3.92e-061911507d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

RASGRF1 ADGRV1 CCDC141 FASN MYH14 ROS1 WWC1

3.92e-061911507276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

PDE1A PDE3B MYLK SVEP1 RYR2 PTPRM MACF1

4.06e-06192150762904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RASGRF1 ADGRV1 CCDC141 PPP4R4 FASN ROS1 WWC1

4.20e-061931507fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPIRE2 ZBTB7C SIDT1 CMYA5 ALS2CL PTPRM MYH14

4.20e-061931507a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

RASGRF1 ADGRV1 CCDC141 PPP4R4 FASN ROS1 WWC1

4.20e-061931507738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RASGRF1 ADGRV1 CCDC141 PPP4R4 FASN ROS1 WWC1

4.20e-061931507f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP34 ATRX ASH1L RB1CC1 AKAP9 MACF1 PKN2

4.35e-061941507e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

ATRX CNTRL RB1CC1 LRRIQ1 AKAP9 SYNE2 SEC16A

4.97e-06198150776d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRF1 ADGRV1 CCDC141 PTPRM MYH14 ROS1 WWC1

5.14e-061991507725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 PDE3B ATRX ASH1L AKAP9 SYNE2 MACF1

5.14e-061991507f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

ATRX CNTRL RB1CC1 LARP7 LRRIQ1 AKAP9 SYNE2

5.14e-061991507fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RNMT ADGRV1 CCDC141 FASN AKAP9 ROS1 WWC1

5.31e-062001507e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNB2 PDE3B BMP2K CARMIL1 ADGRV1 EFR3B WWC1

5.31e-062001507d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNB2 PDE3B BMP2K CARMIL1 ADGRV1 EFR3B WWC1

5.31e-062001507f861509b54185d89931db64da1b9d81986cc7938
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

CNTRL FANCD2 SYNE2 CKAP2L FAM83D DEPDC1B CDCA7L

5.31e-0620015070d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

CNTRL FANCD2 SYNE2 CKAP2L FAM83D DEPDC1B CDCA7L

5.31e-0620015070675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNB2 PDE3B BMP2K CARMIL1 ADGRV1 EFR3B WWC1

5.31e-06200150716f468217427921fa18c6d078ffa990eb019b257
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNB2 PDE3B BMP2K CARMIL1 ADGRV1 EFR3B WWC1

5.31e-0620015070442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNB2 PDE3B BMP2K CARMIL1 ADGRV1 EFR3B WWC1

5.31e-06200150701819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

LRRC8E CYP4V2 ZNF225 ALS2CL PRPF40B NGEF USH2A

5.31e-062001507fe772d98c461c973dfc082e1fc50117c27ced804
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

EVC2 POLR2J3 AKAP9 SYNE2 MACF1 CFAP57

6.55e-061351506ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNTL6 PDE1A PDE1C LOXHD1 ATP6V0D2 UBE2QL1

1.03e-051461506e887e9de895fd453faa703997ef372cc6410fc49
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

B4GALNT1 TBC1D2B KCNJ9 JAKMIP1 USH2A UNC80

1.61e-0515815061f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNB2 EPPK1 ZBTB7C MYLK PPFIA2 PTGDR2

1.73e-05160150629c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1C CNTRL SIDT1 ZNF827 PKP3 JAKMIP1

1.79e-051611506140b3c7077947c541cff54f6754e2df968345f4d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HECW1 ADGRV1 ROS1 ATP6V0D2 USH2A UNC80

1.85e-051621506bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 SIDT1 NCF4 PSTPIP1 JAKMIP1 CDCA7L

2.12e-051661506d80c2522cf314d56730d60f160b1247933443378
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 SIDT1 NCF4 PSTPIP1 JAKMIP1 CDCA7L

2.12e-051661506f2593e2f1043a8cedaa677a73e6b28393991b910
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNTL6 HECW1 RASGRF1 RYR1 KCNN1 CALN1

2.20e-0516715063edb0570e583bb527165bcd8a4c25a042054043b
ToppCellfacs-Kidney-nan-24m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 B4GALNT1 NCF4 RYR1 ZSCAN18 JAKMIP1

2.20e-0516715063c4183a8225bae37b9f5341ebd1b95409ced2022
ToppCellfacs-Kidney-nan-24m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 B4GALNT1 NCF4 RYR1 ZSCAN18 JAKMIP1

2.20e-05167150628e9670586ff551b700c794313d27eedbfa1286b
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE3B SPIRE2 B4GALNT1 PPFIA2 UNC45A JAKMIP1

2.35e-051691506a388e53deac861a185c31e9cceddae7bcb344700
ToppCellfacs-Heart-LV-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 B4GALNT1 DSG3 SIDT1 PKP3 JAKMIP1

2.43e-0517015062491f3849e34b0ccd06015fa59d15e3d7963c76d
ToppCelldroplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 BMP2K CARMIL1 CNTRL CLEC4G JAKMIP1

2.43e-051701506749144a1a869a6bf9acdd227184319083367dc3f
ToppCelldroplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 BMP2K CARMIL1 CNTRL CLEC4G JAKMIP1

2.43e-05170150625d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ACAP1 PDE3B POLR2J3 AKAP9 SYNE2 MACF1

2.51e-0517115062e9a20f8980b78325c52065a9c14ab3656267c05
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRF1 CARMIL1 CNTRL RYR1 CLEC4G JAKMIP1

2.59e-051721506422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRF1 CARMIL1 CNTRL RYR1 CLEC4G JAKMIP1

2.59e-0517215061abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 PDE1A PDE1C LOXHD1 ATP6V0D2 UBE2QL1

2.86e-05175150677c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellfacs-Skin-Telogen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 PDE3B MYLK PSTPIP1 ARL5C JAKMIP1

2.95e-0517615063d372c1d527fcc118d1e5809f2524fc387682472
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

GAD1 CACNB2 PDE1A PDE1C ATP6V0D2 UBE2QL1

2.95e-05176150645028197364c64e93e3ffe86aff773d47a477d49
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNTL6 ALS2CL PPP4R4 FAM153A NGEF ROS1

2.95e-051761506c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCellfacs-Skin-Telogen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 PDE3B MYLK PSTPIP1 ARL5C JAKMIP1

2.95e-0517615067b3f3d9b33770edf294cee0eccaf8a46f9331461
ToppCellfacs-Skin-Telogen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 PDE3B MYLK PSTPIP1 ARL5C JAKMIP1

2.95e-0517615069c0fb2c6ae84febdf7c3d4e648985f597dcffe7a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNTL6 ALS2CL PPP4R4 FAM153A NGEF ROS1

3.05e-0517715068b003ed7887479c3a010ef37dd981b748256bda7
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX CNTRL ASH1L AKAP9 SYNE2 PKN2

3.15e-05178150601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B B4GALNT1 TAF1B NCF4 RGS14 PKP3

3.25e-05179150630efe1f0394c0edb27b91890b5c4637b73cbc5ec
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

RASGRF1 ADGRV1 CCDC141 PPP4R4 FASN ROS1

3.35e-051801506198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RSPH10B2 CCDC13 LRRIQ1 CROCC2 DNAI4 CFAP57

3.45e-051811506dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 CACNB2 PPP4R4 ERC2 JAKMIP1 CALN1

3.56e-051821506d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 CACNB2 PPP4R4 ERC2 JAKMIP1 CALN1

3.56e-0518215066cde859edfe7607bd7ada89d20258413d06f4207
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GAD1 CACNB2 PDE1A PPFIA2 ADGRV1 NINL

3.67e-05183150631ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 KRT12 KRT33B RGS14 ERC2 CALN1

3.67e-051831506bf7f1cb55ed55981b8b355d5774055c96e658ff2
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 EPPK1 PSD DSG3 ARL5B ATP6V0D2

3.67e-051831506bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 KRT12 KRT33B RGS14 ERC2 CALN1

3.67e-0518315069533db4db2c6ae78d7ca1682cf4efed12183396f
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 ACAP1 PDE3B B4GALNT1 NCF4 JAKMIP1

3.67e-05183150620f7b6ec2462032eda957a893ca76d5a5a01333d
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 ADGRV1 CCDC141 FASN MYH14 ROS1

3.79e-0518415060ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 PDE3B B4GALNT1 SIDT1 ALS2CL JAKMIP1

3.79e-051841506cdacb61878e0824b8416bf365d89965797208359
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

RASGRF1 ADGRV1 CCDC141 FASN ROS1 WWC1

3.79e-051841506369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 ADGRV1 CCDC141 FASN MYH14 ROS1

3.79e-0518415062a8338e94937686a148b5433515700ca0f674058
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

RSPH10B2 CCDC13 LRRIQ1 CROCC2 DNAI4 CFAP57

3.90e-05185150630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GAD1 CACNB2 PDE1A PPFIA2 ADGRV1 NINL

3.90e-051851506898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE1A ADGRV1 PPP4R4 MYH14 ROS1 WWC1

4.02e-0518615062ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE1A HECW1 RYR2 LRRIQ1 NGEF ERC2

4.02e-05186150684ba666237c18189d7e7556bd92dd953af733c00
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 B4GALNT1 SIDT1 PSTPIP1 PKP3 JAKMIP1

4.02e-051861506629b19447a63412cf1468160a0fedb5dbe02fd72
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

PDE3B ATRX AKAP9 SYNE2 MACF1

5.25e-0549905GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
DrugU46619

CACNB2 PDE1A PDE1C PDE3B MYLK PTGDR ADCY6 RYR1 RYR2 PTPRM PKN2 PTGDR2

4.37e-0728515012CID000005618
DrugRolitetracycline [751-97-3]; Up 200; 7.6uM; HL60; HT_HG-U133A

GAD1 PDE1C B4GALNT1 PSD DSG3 SRR KCNJ9 EFR3B KCNN1 PTGDR2

7.31e-07196150103031_UP
Druggadolinium

GAD1 CACNB2 B4GALNT1 CDH23 ADGRV1 RYR1 RYR2 NF1 USH2A CDCA7L

8.40e-0719915010CID000023982
DrugRisperidone [106266-06-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A

GAD1 TAF1B RYR2 PPP4R4 NF1 DDX54 FHIP2B SYMPK SOS2

6.05e-0619515093508_DN
DrugTropine [120-29-6]; Down 200; 28.4uM; PC3; HT_HG-U133A

USP34 CNTRL UNC45A PHF8 ALS2CL CARD8 RYR2 NF1 SOS2

6.84e-0619815095790_DN
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A

USP34 PDE1C CNTRL ASH1L ALS2CL XAB2 ZBTB14 RYR2 NF1

7.13e-0619915097029_UP
Drugfelodipine

CACNB2 PDE1A PDE1C PDE3B MYLK RYR1 RYR2 CALN1

1.68e-051691508CID000003333
DrugPF-04254644

PDE1A PDE1C PDE3B

2.29e-0591503ctd:C551178
DrugResveratrol [501-36-0]; Down 200; 17.6uM; PC3; HT_HG-U133A

GAD1 ATRX BMP2K TAF1B NF1 PKP3 WWC1 SOS2

3.74e-0518915085084_DN
DrugAlprenolol hydrochloride [13707-88-5]; Down 200; 14uM; MCF7; HT_HG-U133A

ATRX BMP2K ASH1L SRPRA ALS2CL ZBTB14 NF1 SOS2

4.19e-0519215083188_DN
Drugzaprinast

PDE1A PDE1C PDE3B MYLK ADCY6 RYR1 RYR2

4.23e-051411507CID000005722
Drug(4-chloro-2-((2-methyl-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid

PTGDR PTGDR2

4.31e-0521502ctd:C568957
Drug0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A

PDE1C EPPK1 SIDT1 NCF4 ALS2CL PTPRM KCNN1 DNAI4

4.51e-0519415083969_DN
DrugBAS 012416453; Down 200; 38uM; PC3; HT_HG-U133A

GAD1 RNMT BMP2K ZBTB14 RGS14 AKAP9 SEC16A WWC1

4.51e-0519415086876_DN
DrugHesperetin [520-33-2]; Down 200; 13.2uM; PC3; HG-U133A

PDE1C PNO1 SRPRA SRR RB1CC1 NF1 MYH14 MACF1

4.51e-0519415081947_DN
DrugPilocarpine nitrate [148-72-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A

LRRC8E PDE3B ATRX BMP2K PNO1 PHF8 CARD8 SOS2

5.02e-0519715085341_DN
DrugNoscapine [128-62-1]; Up 200; 9.6uM; HL60; HG-U133A

ACAP1 PDE1C BMP2K TBC1D2B PNO1 ADCY6 MYH14 GEMIN4

5.21e-0519815081753_UP
DrugHydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

PDE3B B4GALNT1 ATRX TBC1D2B ALS2CL EHBP1L1 NF1 SOS2

5.21e-0519815083292_DN
DrugNitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A

LRRC8E USP34 CACNB2 ATRX RYR2 NF1 SYMPK SOS2

5.21e-0519815085405_DN
Diseaseserum gamma-glutamyl transferase measurement

RNMT ZBTB7C ATRX ASH1L TWNK CDC42BPB RYR2 UBE4A NF1 CATSPER2 PTPRM ZNF827 PKN2 JAKMIP1 CCDC171 CDCA7L

1.28e-0591414616EFO_0004532
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2

7.27e-0531462DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2

7.27e-0531462DOID:8545 (implicated_via_orthology)
DiseaseLiposarcoma, Pleomorphic

FASN NF1

1.45e-0441462C0205825
Diseaseliposarcoma

FASN NF1

3.60e-0461462C0023827
DiseaseLiposarcoma, well differentiated

FASN NF1

3.60e-0461462C1370889
DiseaseLiposarcoma, Dedifferentiated

FASN NF1

3.60e-0461462C0205824
DiseaseMalignant Glioma

MYLK ATRX NF1 ROS1

4.09e-04701464C0555198
Diseasemixed gliomas

MYLK ATRX NF1 ROS1

4.09e-04701464C0259783
Diseaseapolipoprotein B measurement

CACNB2 AMPD2 PDE3B PSD SRPRA PPP4R4 NF1 SYNE2 EIF3G HTT SYMPK

4.81e-0466314611EFO_0004615
DiseaseProfound Mental Retardation

LARP7 SYNGAP1 SNX14 FASN NF1

6.54e-041391465C0020796
DiseaseMental Retardation, Psychosocial

LARP7 SYNGAP1 SNX14 FASN NF1

6.54e-041391465C0025363
DiseaseMental deficiency

LARP7 SYNGAP1 SNX14 FASN NF1

6.54e-041391465C0917816
DiseaseNonsyndromic Deafness

CDH23 ADGRV1 LOXHD1 MYH14

7.12e-04811464C3711374
DiseaseGlioma

MYLK ATRX NF1 ROS1

9.31e-04871464C0017638
Diseaseautism spectrum disorder, schizophrenia

CACNB2 CARMIL1 SRR SYNGAP1 NGEF MPHOSPH9 CALN1

1.26e-033271467EFO_0003756, MONDO_0005090
Diseasepolybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement

LOXHD1 PTPRM

1.30e-03111462EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
Diseasehearing impairment

CDH23 ADGRV1 LOXHD1 USH2A

1.45e-03981464C1384666
DiseaseIntellectual Disability

ASH1L LARP7 SYNGAP1 SNX14 FASN NF1 MACF1 HTT

1.78e-034471468C3714756
DiseaseCongenital pontocerebellar hypoplasia

AMPD2 CLP1

1.83e-03131462C0266468
Diseasemental or behavioural disorder

CACNB2 PHF8 CMYA5 PTPRM ERC2

2.01e-031791465EFO_0000677
DiseaseCiliopathies

EVC2 CDH23 ADGRV1 USH2A

2.21e-031101464C4277690
DiseaseDyskinesia, Medication-Induced

GAD1 RASGRF1

2.45e-03151462C0751088
DiseaseDyskinesia, Drug-Induced

GAD1 RASGRF1

2.45e-03151462C0013386
DiseasePontoneocerebellar hypoplasia

AMPD2 CLP1

2.79e-03161462cv:C1261175
Diseasecortical surface area measurement

DHX16 USP34 SPIRE2 SIDT1 ADGRV1 XPO1 PSTPIP1 SVEP1 LRRIQ1 MACF1 ERC2 PKN2 MPHOSPH9 WWC1 SOS2

2.80e-03134514615EFO_0010736
DiseaseHypertrophic Cardiomyopathy

CACNB2 RYR2 FASN

2.86e-03571463C0007194
Diseaseresponse to carboplatin

PDE1A ZNF827 WWC1

3.00e-03581463GO_0097328
Diseasecutaneous melanoma

ADGRV1 SYNE2 CDCA7L FHIP2B

3.12e-031211464EFO_0000389
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

CARMIL1 SYNE2 MACF1 CALN1 HTT

3.25e-032001465EFO_0004611, EFO_0020945
Diseasepulse pressure measurement

USP34 CACNB2 PDE1A RNMT CARMIL1 CNTRL MAEA PNO1 CCDC141 SVEP1 FASN PRPF40B ZNF827 PKN2 SOS2

3.86e-03139214615EFO_0005763
Diseaseneck circumference

GALNTL6 CALN1

3.93e-03191462EFO_0011043
Diseasecytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant

PDE1A CDH23

3.93e-03191462EFO_0007044, EFO_0020106
Diseaseresponse to methotrexate, neurotoxicity

MACF1 PKN1

3.93e-03191462EFO_0011057, GO_0031427
Diseasewhite matter hyperintensity measurement

CACNB2 PDE1C PTGDR QRICH2 GFM2 PKN2

4.01e-033021466EFO_0005665
Diseasealcohol use disorder measurement

CACNB2 SYNGAP1 NF1 ERC2 CLP1

4.32e-032141465EFO_0009458
Diseasetelomere length

ZBTB7C CARMIL1 NINL ERC2 CFAP57 UNC80

4.77e-033131466EFO_0004505
DiseaseInfiltrating duct carcinoma of female breast

CDC42BPB PKN1

4.80e-03211462C3165106
DiseaseArthrogryposis

GFM2 VIPAS39

4.80e-03211462C0003886

Protein segments in the cluster

PeptideGeneStartEntry
EAALLRLEEVFSATL

ALS2CL

6

Q60I27
EERSVLLAAFRTELT

AKAP9

3036

Q99996
DFIAELEELISRLSE

ASH1L

1286

Q9NR48
RFSLEEVERLERDLE

CNTRL

266

Q7Z7A1
LSEDTRETDLQELFR

EIF3G

246

O75821
FIILVVDSIDRERLA

ARL5B

86

Q96KC2
FIILVIDSTDRDRLL

ARL5C

86

A6NH57
DAIRSRLIDTFSLIE

CATSPER2

16

Q96P56
FTARTRLERLVDVLE

B4GALNT1

361

Q00973
IIADFDEIISEERFR

ADCY6

1011

O43306
AEVERRSLRLEVTEF

CCDC171

986

Q6TFL3
TLQDTVLEEDRRFTI

ADGRV1

4106

Q8WXG9
VLEEDRRFTIQLISI

ADGRV1

4111

Q8WXG9
VDLDELLAARLVTFL

DEPDC1B

371

Q8WUY9
RFRASIELVEAEVSE

ACAP1

16

Q15027
IAEELFTRSLAESEL

AMPD2

126

Q01433
EEFVQRLRDTDTLDL

DHX16

41

O60231
TEEELLDREFDLLRS

BMP2K

636

Q9NSY1
SVEELDEIREAFRVL

CALN1

76

Q9BXU9
LVLRDLDREREAIFS

CDH23

2786

Q9H251
SEIERIFELARTLQL

CACNB2

356

Q08289
LDITVTESDLRRAFD

RBM15

381

Q96T37
EEAEDLRALRFLSVI

PTGDR

301

Q13258
EELSFARVLLQRVDE

QRICH2

6

Q9H0J4
SRRALERDDFEIVVI

KCNJ9

261

Q92806
RLVSVFDARELELVI

HECW2

1436

Q9P2P5
DLIESLSEDRARLLE

RB1CC1

1366

Q8TDY2
DELEARLNIFILREE

RSPH10B

806

P0C881
DELEARLNIFILREE

RSPH10B2

806

B2RC85
LSSELLRFQVTDLDE

DSG3

281

P32926
LTLREELRSLEEFRE

PSTPIP1

96

O43586
LDREEEAELRLTLTA

PCDHB13

201

Q9Y5F0
LFERIIDEDFELTER

MYLK

1546

Q15746
LEFSLRIQEFIELIR

MAEA

196

Q7L5Y9
RRVLDELTLTRTDLE

KRT12

236

Q99456
SERLIRTSLDLELDL

WWC1

981

Q8IX03
LVSVFDARELELVIA

HECW1

1471

Q76N89
IADSLILREISAFDV

CFAP57

581

Q96MR6
EELEARLATLESRLD

KCNN1

476

Q92952
ERDSIEIFTVETLDL

LOXHD1

1016

Q8IVV2
RFEEEELQRLRLVDS

DDX54

551

Q8TDD1
TQSDIDFLIEEIERL

GAD1

576

Q99259
ERELFQETLESLRVL

MYH14

341

Q7Z406
DEISITTLRLFEELL

FHIP2B

446

Q86V87
TRRLLDTEDELSDIQ

PDE1A

71

P54750
VLESVYIDETRRLLD

PDE1C

71

Q14123
RFRFLVIEAILATDL

PDE3B

881

Q13370
EDAEIRLFVLEILIS

EFR3B

466

Q9Y2G0
ELFSESRRLALEELV

FAM83D

26

Q9H4H8
TLAEFLIRDVLQELS

FAM153A

141

Q9UHL3
FDFLERLSDDLLLTI

FBXO36

91

Q8NEA4
EQDLERRFELLSREL

EHBP1L1

1431

Q8N3D4
IRTLAETERFFDELT

MPHOSPH9

956

Q99550
RELRVLIDDSQSIIF

MRS2

311

Q9HD23
LELTRREFQREDIAL

NCF4

271

Q15080
TRLEVEIETYRRLLD

KRT24

436

Q2M2I5
ERLDQAALDDLRTLT

EVC2

726

Q86UK5
LSRELASTERELDEA

LIX1L

291

Q8IVB5
ARALRSSAVVELDLE

LARP7

91

Q4G0J3
LSLTRDEQEIEFLRL

JAKMIP1

386

Q96N16
DTVFELSEVESLRLE

LRRC8E

431

Q6NSJ5
TEELRRIFIEDTDSE

CDCA7L

66

Q96GN5
EVDALRLRLEEKESF

ERC2

491

O15083
RDAEVVLTSRELDSL

TWNK

256

Q96RR1
ALIRLDDLFLESFEI

PNO1

151

Q9NRX1
VLDLRDDEFSVSSVL

CDC42BPB

1146

Q9Y5S2
VEAELRSRLATLETE

PPP1R21

136

Q6ZMI0
RELTERAKDFSLILD

PHB2

166

Q99623
RRSLRTVLESVLVDD

PTGDR2

316

Q9Y5Y4
LVARLVSREDTDLDL

LRRIQ1

1671

Q96JM4
DSVLFSVADRLRLEE

MACF1

1006

Q9UPN3
ENEVSLLLEESDLRR

ATRX

641

P46100
TELLETLAEIDFRLV

HTT

866

P42858
ERRTELLRLTSEFFE

CCDC141

121

Q6ZP82
DLRVERDSLESSLLE

CROCC2

786

H7BZ55
TIVREAEELDEAVFL

CMYA5

3641

Q8N3K9
AEVERDRLTEFVTVL

CCDC13

556

Q8IYE1
DLALDVLFRSISERD

CARD8

511

Q9Y2G2
RRAFLDLLLSVTDDE

CYP4V2

296

Q6ZWL3
SFELIRRLEASETES

RNMT

321

O43148
IEIILTETETLRFFD

DNAI4

236

Q5VTH9
VASFLSDRIVDEILD

CARMIL1

841

Q5VZK9
VSLEVRLLEASRAFE

FASN

931

P49327
ELLVRDEFSVLCRDL

RYR1

3391

P21817
AELLILDEFTTLARD

RYR2

3351

Q92736
REDVLSLLETFQLDT

FANCD2

1321

Q9BXW9
RVSLERVSALEEELA

PPFIA2

196

O75334
SADLEEDIISRIFRI

PTPRM

1316

P28827
LDREEEAELRLTLTA

PCDHB8

201

Q9UN66
TDLISELSLLEERFR

POLR2J3

91

Q9H1A7
LIAEIILVDDFSERE

GALNTL6

171

Q49A17
TLFIRELFERETKII

USH2A

4566

O75445
FVLTSLVALRREVEE

RMDN3

96

Q96TC7
LFVRSDASREELAEL

XAB2

796

Q9HCS7
SDLAELRELSEVLRE

TMEM41A

46

Q96HV5
VDFTLEVERCLRVLD

GFM2

146

Q969S9
DFERDLELLERLESF

SOS2

701

Q07890
RLTVDEDLSDIERAV

PPP4R4

46

Q6NUP7
AIDEEELRRSLSELA

PSD

711

A5PKW4
VRRELAELSNFLEED

RNF151

196

Q2KHN1
LVEETEERLVERISF

SYNE2

4866

Q8WXH0
REAITLSDLLRFVEE

TAF1B

226

Q53T94
ALTRRLTAIIEEAEE

EPPK1

2566

P58107
VLDVLAVSERFLLEL

NGEF

321

Q8N5V2
TEFDRQAEVTRLLLE

SH3GLB2

226

Q9NR46
FATEAAITILRIDDL

TCP1

516

P17987
DQSFTLELERARELE

PKN1

416

Q16512
IIRDLVDDIFTVTED

SRR

251

Q9GZT4
FTLELDRSRELEISV

PKN2

421

Q16513
RLSLLRSEVEAEREL

NINL

446

Q9Y2I6
RELSERLELVFLVDD

SVEP1

76

Q4LDE5
ASVERLLERLTDLRF

RASGRF1

651

Q13972
ELERETELRFEVEAS

CLP1

16

Q92989
REDVRTELFRALEAV

CLEC4G

141

Q6UXB4
ELLEVEETKCFIFRR

CKAP2L

716

Q8IYA6
IRISASILDLRDSFD

CLCA4

791

Q14CN2
LRRLEELITIFREEA

CDK5RAP1

496

Q96SZ6
TDLISELSLLEERFR

POLR2J2

91

Q9GZM3
FELLRTLREQDDELR

PKP3

406

Q9Y446
RLRLELADTELEDFT

ULBP3

101

Q9BZM4
IEIDFLRSDIFEEVL

ZBTB14

76

O43829
SDLFLEEREIALRQA

XPO1

1031

O14980
DIARLSDRFISVELV

UBE2QL1

6

A1L167
VEDLLDISSVDRLSF

UNC80

1101

Q8N2C7
ASSLERETERFRELL

SEC16A

1611

O15027
REDIADRLISASLFL

SYNGAP1

581

Q96PV0
VTDDESFVDELRITL

SNX14

156

Q9Y5W7
LRRLEDLSESIVNDF

TMED10

151

P49755
LFVETLELRAFLARV

SPIRE2

196

Q8WWL2
FLVLLTLDDDLDVVR

SIDT1

806

Q9NXL6
VEEEAELLRRSSAEL

SOGA1

281

O94964
LAETVLADRFERLVE

NF1

1196

P21359
DFLRLLREAEESSKI

SRPRA

116

P08240
ITLESERIRLFREFL

PRPF40B

666

Q6NWY9
RILEFQDSIALIEDL

ROS1

1506

P08922
EVRLENRITFELELT

RGS14

366

O43566
NRITFELELTALERV

RGS14

371

O43566
LDLFRFLDRTEELAL

VIPAS39

241

Q9H9C1
SFILEDVRARLDLAF

SYMPK

606

Q92797
VFTEEELRLLDLAQR

ZNF225

16

Q9UK10
LELVALDSEVLRDSL

ZNF827

81

Q17R98
VIRDFSIESLLRENL

ZBTB7C

221

A1YPR0
DAASRLDTEELRLVE

ZSCAN18

256

Q8TBC5
ELRSRTFDSSDEVIL

PHF8

126

Q9UPP1
ISAFRILLESDEDRL

USP34

2946

Q70CQ2
ILLESDEDRLLVVFN

USP34

2951

Q70CQ2
LIFLRRFADDILETS

UBE4A

636

Q14139
ELTELEAIREDFLRE

TBC1D2B

931

Q9UPU7
LLSRVFLALVEEVED

UNC45A

666

Q9H3U1
ITDLISELSLLEERF

POLR2J

91

P52435
ILEFEADRRAFIITL

ATP6V0D2

211

Q8N8Y2
ILEFEADRRAFIITI

ATP6V0D1

211

P61421
RLDVEEVDLSLRIFI

GEMIN4

661

P57678
ESDINSLRRILDELT

KRT33B

156

Q14525