Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	costamere	ANK2 SYNM AHNAK CMYA5	5.97e-07	22	65	4	GO:0043034
GeneOntologyCellularComponent	myofibril	HABP4 ANK2 XIRP2 SYNM AHNAK SCN8A CMYA5 RPL4	2.02e-06	273	65	8	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	HABP4 ANK2 XIRP2 SYNM AHNAK SCN8A CMYA5 RPL4	3.17e-06	290	65	8	GO:0043292
GeneOntologyCellularComponent	sarcomere	HABP4 ANK2 XIRP2 SYNM SCN8A CMYA5 RPL4	1.21e-05	249	65	7	GO:0030017
GeneOntologyCellularComponent	supramolecular fiber	HABP4 RPGRIP1L ANK2 XIRP2 SYNM AHNAK SCN8A TPX2 AKAP13 CMYA5 SPAG17 DYSF RPL4	5.77e-05	1179	65	13	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	HABP4 RPGRIP1L ANK2 XIRP2 SYNM AHNAK SCN8A TPX2 AKAP13 CMYA5 SPAG17 DYSF RPL4	6.19e-05	1187	65	13	GO:0099081
GeneOntologyCellularComponent	nuclear protein-containing complex	ATF7 SETD1A EXOSC9 INTS14 ARID4B GON4L CHD8 CCDC12 SRCAP KMT2E SARNP CREM EPB41L2 MYBL2	6.90e-05	1377	65	14	GO:0140513
GeneOntologyCellularComponent	parallel fiber to Purkinje cell synapse	PCLO SCN8A GRIN2A	3.24e-04	43	65	3	GO:0098688
GeneOntologyCellularComponent	A band	ANK2 CMYA5 RPL4	5.69e-04	52	65	3	GO:0031672
GeneOntologyCellularComponent	nuclear chromosome	EXOSC9 ARID4B GON4L SRCAP KMT2E	1.16e-03	254	65	5	GO:0000228
GeneOntologyCellularComponent	Z disc	ANK2 XIRP2 SYNM SCN8A	1.26e-03	151	65	4	GO:0030018
GeneOntologyCellularComponent	I band	ANK2 XIRP2 SYNM SCN8A	1.78e-03	166	65	4	GO:0031674
GeneOntologyCellularComponent	chromatin	MYCL ATF7 SETD1A TGM2 ARID4B SUPT7L KAT6A GON4L CHD8 SRCAP KMT2E CREM	1.83e-03	1480	65	12	GO:0000785
GeneOntologyCellularComponent	T-tubule	ANK2 AHNAK DYSF	1.92e-03	79	65	3	GO:0030315
GeneOntologyCellularComponent	nuclear speck	SETD1A HABP4 KAT6A CMYA5 KMT2E SARNP	2.20e-03	431	65	6	GO:0016607
GeneOntologyCellularComponent	histone deacetylase complex	ARID4B SRCAP KMT2E	2.36e-03	85	65	3	GO:0000118
GeneOntologyCellularComponent	postsynaptic density	ANK2 PCLO SCN8A PALM GRIN2A RPL4	2.75e-03	451	65	6	GO:0014069
GeneOntologyCellularComponent	sarcolemma	ANK2 SYNM AHNAK DYSF	2.91e-03	190	65	4	GO:0042383
GeneOntologyCellularComponent	anchoring junction	TGM2 RPGRIP1L ANK2 XIRP2 SYNM AHNAK KDR RPL4 EPB41L2	3.10e-03	976	65	9	GO:0070161
GeneOntologyCellularComponent	terminal bouton	PCLO AAK1 GRIN2A	3.34e-03	96	65	3	GO:0043195
GeneOntologyCellularComponent	INO80-type complex	GON4L SRCAP	3.42e-03	28	65	2	GO:0097346
GeneOntologyCellularComponent	asymmetric synapse	ANK2 PCLO SCN8A PALM GRIN2A RPL4	3.63e-03	477	65	6	GO:0032279
MousePheno	decreased heart ventricle muscle contractility	SYNM AKAP13 CMYA5 CREM RBM20	6.14e-05	107	55	5	MP:0005598
MousePheno	abnormal diastolic filling velocity	XIRP2 RBM20	9.07e-05	4	55	2	MP:0004009
MousePheno	decreased heart left ventricle muscle contractility	SYNM AKAP13 CREM RBM20	1.29e-04	66	55	4	MP:0031633
MousePheno	spleen hypoplasia	RPGRIP1L KAT6A GON4L AKAP13 KMT2E	1.43e-04	128	55	5	MP:0000694
MousePheno	small spleen	RPGRIP1L KAT6A LRRC8A GON4L AKAP13 KMT2E RBM20 METTL14	2.05e-04	416	55	8	MP:0000692
MousePheno	decreased cardiac muscle contractility	ANK2 SYNM AKAP13 CMYA5 CREM RBM20	2.33e-04	223	55	6	MP:0005140
MousePheno	skeletal muscle necrosis	SYNM SCN8A DYSF	2.40e-04	31	55	3	MP:0003852
MousePheno	abnormal pro-B cell morphology	KAT6A LRRC8A GON4L KMT2E	2.47e-04	78	55	4	MP:0005432
MousePheno	abnormal heart atrium morphology	RPGRIP1L XIRP2 KAT6A SCN8A CMYA5 RBM20	2.88e-04	232	55	6	MP:0003105
MousePheno	cardiac fibrosis	ANK2 SYNM AKAP13 CMYA5 RBM20	3.10e-04	151	55	5	MP:0003141
MousePheno	ventricular fibrillation	TGM2 RBM20	3.15e-04	7	55	2	MP:0006110
Domain	MRFAP1	MRFAP1 MRFAP1L1	1.27e-05	2	67	2	IPR029254
Domain	MRFAP1	MRFAP1 MRFAP1L1	1.27e-05	2	67	2	PF15155
Domain	Tscrpt_reg_Myc_N	MYCL MYCLP1	7.57e-05	4	67	2	IPR012682
Domain	Tscrpt_reg_Myc	MYCL MYCLP1	7.57e-05	4	67	2	IPR002418
Domain	Myc_N	MYCL MYCLP1	7.57e-05	4	67	2	PF01056
Domain	FerI	DYSF FER1L6	1.26e-04	5	67	2	SM01202
Domain	FerB	DYSF FER1L6	1.26e-04	5	67	2	SM01201
Domain	Ferlin_B-domain	DYSF FER1L6	1.26e-04	5	67	2	IPR012561
Domain	Ferlin_C	DYSF FER1L6	1.26e-04	5	67	2	PF16165
Domain	Ferlin_C	DYSF FER1L6	1.26e-04	5	67	2	IPR032362
Domain	FerIin_dom	DYSF FER1L6	1.26e-04	5	67	2	IPR012968
Domain	FerI	DYSF FER1L6	1.26e-04	5	67	2	PF08151
Domain	FerB	DYSF FER1L6	1.26e-04	5	67	2	PF08150
Domain	DUF1220	NBPF4 NBPF6	4.49e-04	9	67	2	SM01148
Domain	NBPF_dom	NBPF4 NBPF6	6.83e-04	11	67	2	IPR010630
Domain	NBPF	NBPF4 NBPF6	6.83e-04	11	67	2	PS51316
Domain	DUF1220	NBPF4 NBPF6	6.83e-04	11	67	2	PF06758
Domain	C2	RPGRIP1L PCLO DYSF FER1L6	1.26e-03	131	67	4	PF00168
Domain	C2	RPGRIP1L PCLO DYSF FER1L6	1.49e-03	137	67	4	SM00239
Domain	C2	RPGRIP1L PCLO DYSF FER1L6	1.69e-03	142	67	4	PS50004
Domain	-	RPGRIP1L PCLO DYSF FER1L6	1.97e-03	148	67	4	2.60.40.150
Domain	C2_dom	RPGRIP1L PCLO DYSF FER1L6	2.86e-03	164	67	4	IPR000008
Domain	VWFA	CLCA4 INTS14 HMCN2	3.19e-03	82	67	3	PS50234
Domain	VWA	CLCA4 INTS14 HMCN2	3.42e-03	84	67	3	SM00327
Domain	VWF_A	CLCA4 INTS14 HMCN2	5.41e-03	99	67	3	IPR002035
Domain	SNF2_N	CHD8 SRCAP	5.87e-03	32	67	2	IPR000330
Domain	Chromodomain-like	ARID4B CHD8	5.87e-03	32	67	2	IPR016197
Domain	SNF2_N	CHD8 SRCAP	5.87e-03	32	67	2	PF00176
Domain	Chromo/shadow_dom	ARID4B CHD8	6.23e-03	33	67	2	IPR000953
Domain	CHROMO	ARID4B CHD8	6.23e-03	33	67	2	SM00298
Domain	bZIP_1	ATF7 CREM	6.60e-03	34	67	2	PF00170
Domain	Helicase_C	CHD8 SRCAP DHX34	6.71e-03	107	67	3	PF00271
Domain	HELICc	CHD8 SRCAP DHX34	6.71e-03	107	67	3	SM00490
Domain	Helicase_C	CHD8 SRCAP DHX34	6.89e-03	108	67	3	IPR001650
Domain	DNA/RNA_helicase_DEAH_CS	CHD8 DHX34	6.99e-03	35	67	2	IPR002464
Domain	HELICASE_CTER	CHD8 SRCAP DHX34	7.07e-03	109	67	3	PS51194
Domain	HELICASE_ATP_BIND_1	CHD8 SRCAP DHX34	7.07e-03	109	67	3	PS51192
Domain	DEXDc	CHD8 SRCAP DHX34	7.07e-03	109	67	3	SM00487
Pathway	WP_GASTRIC_CANCER_NETWORK_1	TPX2 CEP192 MYBL2	1.01e-04	28	46	3	M39347
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SETD1A INTS14 GTF3C1 AHNAK TPX2 GON4L CHD8 SRCAP EPB41L2	6.72e-08	394	67	9	27248496
Pubmed	Chromodomain helicase binding protein 8 (Chd8) is a novel A-kinase anchoring protein expressed during rat cardiac development.	SYNM AKAP13 CHD8	6.81e-08	5	67	3	23071553
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYCL SETD1A AHNAK KAT6A SCN8A PALM AKAP13 CHD8 CEP192 SRCAP DYSF DHX34 MYBL2	1.62e-07	1105	67	13	35748872
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	ARID4B GTF3C1 TPX2 GON4L CHD8 SRCAP	4.68e-07	150	67	6	28242625
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SFMBT1 ATF7 INTS14 ARID4B GTF3C1 AHNAK SUPT7L TPX2 CCDC12 SRCAP RPL4 CREM MYBL2	9.65e-07	1294	67	13	30804502
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SETD1A EXOSC9 RPGRIP1L GTF3C1 AHNAK TPX2 CHD8 CCDC12	3.35e-06	469	67	8	27634302
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	EXOSC9 GTF3C1 AHNAK TPX2 CHD8 SRCAP RPL4	3.61e-06	332	67	7	32786267
Pubmed	Multiple developmental roles of Ahnak are suggested by localization to sites of placentation and neural plate fusion in the mouse conceptus.	AHNAK KDR	3.66e-06	2	67	2	14516657
Pubmed	The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.	MYCL MYCLP1	3.66e-06	2	67	2	3054516
Pubmed	Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.	MYCL MYCLP1	3.66e-06	2	67	2	2827002
Pubmed	Tissue transglutaminase interacts with protein kinase A anchor protein 13 in prostate cancer.	TGM2 AKAP13	3.66e-06	2	67	2	16301118
Pubmed	Increased Set1 binding at the promoter induces aberrant epigenetic alterations and up-regulates cyclic adenosine 5'-monophosphate response element modulator alpha in systemic lupus erythematosus.	SETD1A CREM	3.66e-06	2	67	2	27904655
Pubmed	Complex formation between tissue transglutaminase II (tTG) and vascular endothelial growth factor receptor 2 (VEGFR-2): proposed mechanism for modulation of endothelial cell response to VEGF.	TGM2 KDR	3.66e-06	2	67	2	16914140
Pubmed	Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.	SETD1A GTF3C1 CHD8	4.56e-06	17	67	3	21653943
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ANK2 XIRP2 MRFAP1 GON4L CMYA5 KMT2E DYSF MRFAP1L1	5.12e-06	497	67	8	23414517
Pubmed	USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.	SETD1A GTF3C1 CHD8	5.46e-06	18	67	3	17846119
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1A TGM2 GTF3C1 AHNAK AAK1 AKAP13 CHD8 SRCAP DHX34 RPL4 GRSF1 EPB41L2	9.47e-06	1353	67	12	29467282
Pubmed	MLL5, a histone modifying enzyme, regulates androgen receptor activity in prostate cancer cells by recruiting co-regulators, HCF1 and SET1.	SETD1A KMT2E	1.10e-05	3	67	2	33050986
Pubmed	MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth.	CHL1 ANK2	1.10e-05	3	67	2	16597699
Pubmed	METTL14-mediated m6A epitranscriptomic modification contributes to chemotherapy-induced neuropathic pain by stabilizing GluN2A expression via IGF2BP2.	GRIN2A METTL14	1.10e-05	3	67	2	38319733
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	EXOSC9 ARID4B GTF3C1 MARK3 KAT6A TPX2 SARNP RPL4 GRSF1	1.48e-05	759	67	9	35915203
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	SFMBT1 ERP44 GTF3C1 AHNAK CHD8 RBM20 MYBL2	1.61e-05	418	67	7	34709266
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ATF7 INTS14 ARID4B GTF3C1 TPX2 CHD8 RPL4 EPB41L2	1.63e-05	583	67	8	29844126
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ANK2 AHNAK PCLO AAK1 GRIN2A EPB41L2	1.74e-05	281	67	6	28706196
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SETD1A AEBP1 XIRP2 TPX2 AKAP13 KDR KMT2E	1.93e-05	430	67	7	35044719
Pubmed	PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice.	MRFAP1 MRFAP1L1	2.19e-05	4	67	2	15367658
Pubmed	Myc and Max: molecular evolution of a family of proto-oncogene products and their dimerization partner.	MYCL MYCLP1	2.19e-05	4	67	2	7479755
Pubmed	AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.	AHNAK DYSF	2.19e-05	4	67	2	17185750
Pubmed	Titin splicing regulates cardiotoxicity associated with calpain 3 gene therapy for limb-girdle muscular dystrophy type 2A.	DYSF RBM20	2.19e-05	4	67	2	31776291
Pubmed	Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain.	MRFAP1 MRFAP1L1	2.19e-05	4	67	2	16407074
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETD1A EXOSC9 GTF3C1 TPX2 CHD8 SRCAP SARNP	2.24e-05	440	67	7	34244565
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	TGM2 AHNAK PCLO SCN8A AKAP13 CHD8 SRCAP SPAG17 RPL4	2.40e-05	807	67	9	30575818
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	HABP4 EXOSC9 MARK3 CRACDL SUPT7L TPX2 AAK1 GON4L CHD8 GRSF1 EPB41L2 METTL14	2.58e-05	1497	67	12	31527615
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TGM2 EXOSC9 GTF3C1 SYNM MARK3 AHNAK TPX2 LRRC8A RPL4 EPB41L2 METTL14	2.64e-05	1257	67	11	36526897
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	INTS14 ERP44 SCN8A SRCAP SARNP METTL14 MYBL2	2.85e-05	457	67	7	32968282
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TGM2 GTF3C1 GON4L AKAP13 CHD8 DHX34 RBM20 EXOC8	3.52e-05	650	67	8	38777146
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	GON4L CHD8 CEP192 METTL14	4.46e-05	101	67	4	10997877
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ANK2 CAMKK1 PCLO AAK1 PALM GRIN2A	5.65e-05	347	67	6	17114649
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TGM2 HABP4 EXOSC9 ANK2 MARK3 AHNAK TPX2 AAK1 LRRC8A GRSF1 EPB41L2	5.80e-05	1371	67	11	36244648
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A AAK1 LRRC8A PALM CHD8 DHX34 METTL14	7.16e-05	529	67	7	14621295
Pubmed	Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.	ANK2 SCN8A	7.63e-05	7	67	2	15272007
Pubmed	Genome-wide assessments reveal extremely high levels of polymorphism of two active families of mouse endogenous retroviral elements.	MARK3 DYSF	7.63e-05	7	67	2	18454193
Pubmed	MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner.	MRFAP1 MYBL2	7.63e-05	7	67	2	14506250
Pubmed	Human transcription factor protein interaction networks.	SETD1A ARID4B GTF3C1 SUPT7L TPX2 GON4L CHD8 CEP192 SRCAP RBM20 MYBL2	8.40e-05	1429	67	11	35140242
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	AHNAK TPX2 GON4L KDR FER1L6	9.08e-05	234	67	5	36243803
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	SETD1A KMT2E	1.02e-04	8	67	2	23130995
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	SFMBT1 GTF3C1 SUPT7L MYBL2	1.02e-04	125	67	4	32891193
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SFMBT1 RPGRIP1L SYNM AHNAK CEP192 RPL4 GRSF1 EPB41L2	1.22e-04	777	67	8	35844135
Pubmed	Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.	ANK2 SCN8A	1.30e-04	9	67	2	17884088
Pubmed	TBR1 regulates autism risk genes in the developing neocortex.	ANK2 CHD8	1.30e-04	9	67	2	27325115
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	SETD1A SUPT7L TPX2 CHD8	1.34e-04	134	67	4	25452129
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	SYNM AHNAK TPX2 PHLPP1 EPB41L2	1.38e-04	256	67	5	33397691
Pubmed	Claudin-4 localization in epithelial ovarian cancer.	MARK3 AHNAK EPB41L2	1.58e-04	54	67	3	36237976
Pubmed	Development and application of a DNA microarray-based yeast two-hybrid system.	MRFAP1 RPL4 CREM MRFAP1L1	1.63e-04	141	67	4	23275563
Pubmed	Differential effects of the widely expressed dMax splice variant of Max on E-box vs initiator element-mediated regulation by c-Myc.	MYCL MYCLP1	1.63e-04	10	67	2	10229200
Pubmed	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	EXOSC9 MARK3 PCLO	1.67e-04	55	67	3	18570454
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ARID4B GTF3C1 KAT6A TPX2 CHD8 SRCAP MYBL2	1.69e-04	608	67	7	36089195
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	ATF7 INTS14 GTF3C1 AHNAK MRFAP1 KAT6A PALM KDR TNMD CREM	1.76e-04	1293	67	10	15342556
Pubmed	Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.	TGM2 CHD8 GRIN2A	1.76e-04	56	67	3	30104731
Pubmed	New nomenclature for chromatin-modifying enzymes.	SETD1A KAT6A KMT2E	1.86e-04	57	67	3	18022353
Pubmed	Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis.	ARID4B CREM	1.99e-04	11	67	2	26258622
Pubmed	Dysferlin interacts with tubulin and microtubules in mouse skeletal muscle.	AHNAK DYSF	1.99e-04	11	67	2	20405035
Pubmed	Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling.	XIRP2 CMYA5	1.99e-04	11	67	2	30410445
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KAT6A CHD8 SRCAP METTL14	2.46e-04	157	67	4	30186101
Pubmed	The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.	KDR CREM	2.81e-04	13	67	2	25694434
Pubmed	Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning.	AEBP1 KDR	2.81e-04	13	67	2	29618843
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	TGM2 GTF3C1 SNX7 MRFAP1 GPCPD1 KDR SARNP DHX34 MYBL2	2.96e-04	1124	67	9	21900206
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	HABP4 ARID4B SCN8A LRRC8A CHD8 RPL4	3.10e-04	475	67	6	31040226
Pubmed	Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.	RPGRIP1L DPP10	3.28e-04	14	67	2	21254220
Pubmed	Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing.	MARK3 DYSF	3.78e-04	15	67	2	19436707
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ANK2 GTF3C1 AHNAK PCLO PALM KDR SRCAP SPAG17 RPL4 FER1L6	4.19e-04	1442	67	10	35575683
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	GTF3C1 TPX2 AAK1 AKAP13 CHD8 EPB41L2	4.20e-04	503	67	6	16964243
Pubmed	Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.	ANK2 AHNAK	4.31e-04	16	67	2	21745462
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	RPGRIP1L SYNM CEP192 RPL4	4.48e-04	184	67	4	32908313
Pubmed	Tagging genes with cassette-exchange sites.	TPX2 AKAP13 CHD8 CCDC12 DYSF	4.77e-04	335	67	5	15741177
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	EXOSC9 ARID4B AHNAK TPX2 CHD8 SARNP CREM MYBL2	4.86e-04	954	67	8	36373674
Pubmed	Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors.	MARK3 KDR	4.88e-04	17	67	2	22615585
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SETD1A GTF3C1 TPX2 CHD8 SRCAP	5.17e-04	341	67	5	32971831
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	ANK2 SCN8A	5.48e-04	18	67	2	37321992
Pubmed	Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice.	SYNM AKAP13	5.48e-04	18	67	2	31541165
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	GTF3C1 TPX2 CHD8 SARNP EPB41L2 METTL14	5.70e-04	533	67	6	30554943
Pubmed	HIV tat and neurotoxicity.	KDR GRIN2A	6.12e-04	19	67	2	16697675
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	GTF3C1 AHNAK AAK1 GON4L DHX34 GRSF1	6.53e-04	547	67	6	37267103
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A GTF3C1 AHNAK TPX2 CHD8 SRCAP	6.65e-04	549	67	6	38280479
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	RPGRIP1L TPX2 AKAP13 RPL4 EPB41L2	6.68e-04	361	67	5	30344098
Pubmed	Germline Chd8 haploinsufficiency alters brain development in mouse.	ANK2 CHD8	6.79e-04	20	67	2	28671691
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	ATF7 GTF3C1 AHNAK TPX2 CHD8 CCDC12 SARNP METTL14	7.24e-04	1014	67	8	32416067
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF4 NBPF6	7.50e-04	21	67	2	16079250
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	SETD1A KMT2E	8.24e-04	22	67	2	26886794
Pubmed	Comprehensive identification of human bZIP interactions with coiled-coil arrays.	ATF7 CREM	9.01e-04	23	67	2	12805554
Pubmed	HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.	KAT6A KDR	9.82e-04	24	67	2	21149574
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	PCLO GRIN2A RPL4 EPB41L2	1.05e-03	231	67	4	16452087
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SETD1A SYNM SRCAP	1.08e-03	104	67	3	9205841
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	EXOSC9 MRFAP1 TPX2 CCDC12 SARNP	1.09e-03	403	67	5	35253629
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ERP44 PCLO PHLPP1	1.11e-03	105	67	3	9628581
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	ATF7 AHNAK RPL4 EPB41L2	1.12e-03	235	67	4	30258100
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	EXOSC9 AHNAK RPL4	1.14e-03	106	67	3	19394292
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SETD1A EXOSC9 GTF3C1 TPX2 CHD8	1.18e-03	410	67	5	26949251
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	INTS14 GTF3C1 TPX2 CHD8 SARNP	1.19e-03	411	67	5	35182466
Pubmed	Discovery of novel protein partners of the transcription factor FOXL2 provides insights into its physiopathological roles.	RPL4 CREM	1.24e-03	27	67	2	22544055
Interaction	H3C1 interactions	SFMBT1 SETD1A EXOSC9 ARID4B ANK2 GTF3C1 XIRP2 AHNAK KAT6A TPX2 CHD8 SRCAP SARNP	5.92e-06	901	66	13	int:H3C1
Interaction	H2BC8 interactions	TGM2 EXOSC9 ARID4B GTF3C1 TPX2 GON4L CHD8 SRCAP SARNP MYBL2	1.68e-05	576	66	10	int:H2BC8
Cytoband	9q34.11	HMCN2 LRRC8A	2.76e-03	53	67	2	9q34.11
Cytoband	1p13.3	NBPF4 NBPF6	4.62e-03	69	67	2	1p13.3
Cytoband	12q13	ATF7 SCN8A	4.89e-03	71	67	2	12q13
Cytoband	4p16.1	MRFAP1 MRFAP1L1	6.01e-03	79	67	2	4p16.1
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	SYNM AKAP13 CMYA5	6.91e-05	29	50	3	396
GeneFamily	Ferlin family	DYSF FER1L6	1.12e-04	6	50	2	828
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6	1.83e-03	23	50	2	662
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A KMT2E	3.97e-03	34	50	2	487
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RPGRIP1L PCLO	4.45e-03	36	50	2	823
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	ANK2 XIRP2 AAK1 AKAP13 CMYA5 RBM20	3.50e-07	184	67	6	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ANK2 MACROD2 AAK1 AKAP13 CMYA5 RBM20	4.35e-07	191	67	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGM2 SYNM PALM KDR DYSF CREM	4.49e-07	192	67	6	ee9a23a4f00424a50bd7907cf3b12dc50027877e
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYNM PALM KDR CMYA5 DYSF EPB41L2	4.63e-07	193	67	6	bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	ANK2 XIRP2 MACROD2 AKAP13 CMYA5 RBM20	4.92e-07	195	67	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	Control-B_naive-8\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ARID4B AEBP1 MACROD2 AAK1 CREM MYBL2	5.06e-07	196	67	6	54074da84000e4749ade8acc542f05a275bf829f
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 TGM2 AEBP1 CMYA5 SRCAP	3.82e-06	156	67	5	bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGM2 CLCA4 AEBP1 PALM KDR	4.45e-06	161	67	5	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGM2 CLCA4 AEBP1 PALM KDR	4.45e-06	161	67	5	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGM2 CLCA4 AEBP1 PALM KDR	4.45e-06	161	67	5	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYNM PALM KDR DYSF EPB41L2	6.32e-06	173	67	5	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANK2 PCLO KDR CMYA5 EPB41L2	7.45e-06	179	67	5	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	Endothelial-B-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	AEBP1 SYNM PALM KDR EPB41L2	7.87e-06	181	67	5	4fe0215d08f03d4e24749d70fce01b7aa22906fd
ToppCell	RV\|World / Chamber and Cluster_Paper	XIRP2 MARK3 AAK1 CMYA5 RBM20	7.87e-06	181	67	5	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 XIRP2 SYNM CMYA5 RBM20	8.30e-06	183	67	5	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	ILEUM-inflamed-(7)_Lymphatics\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SYNM PCLO KDR CMYA5 EPB41L2	8.75e-06	185	67	5	d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK2 XIRP2 AAK1 CMYA5 RBM20	8.75e-06	185	67	5	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SYNM PCLO PALM KDR DYSF	9.21e-06	187	67	5	55aad84b992412e487a32f4970620189a7380ba6
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	XIRP2 MACROD2 AAK1 CMYA5 RBM20	9.45e-06	188	67	5	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	wk_15-18-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SYNM PCLO PALM KDR DYSF	9.70e-06	189	67	5	f0418851ad4042c4cd87c8729e4f0d43bdf8fccb
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ANK2 XIRP2 AKAP13 CMYA5 RBM20	9.70e-06	189	67	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK2 XIRP2 AKAP13 CMYA5 RBM20	9.70e-06	189	67	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	ANK2 XIRP2 AKAP13 CMYA5 RBM20	9.95e-06	190	67	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ANK2 AAK1 AKAP13 CMYA5 RBM20	9.95e-06	190	67	5	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 XIRP2 SYNM CMYA5 RBM20	9.95e-06	190	67	5	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SYNM AHNAK PCLO PALM EPB41L2	1.05e-05	192	67	5	b016e229300c183e14c0e2bba494bf49c7899112
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ANK2 MACROD2 AAK1 CMYA5 RBM20	1.05e-05	192	67	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SYNM AHNAK PCLO PALM EPB41L2	1.05e-05	192	67	5	ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANK2 SYNM PCLO CMYA5 EPB41L2	1.05e-05	192	67	5	d43caf42ec744e895137f31ef65a990e250669d2
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYCL CAMKK1 AKAP13 CREM MYBL2	1.07e-05	193	67	5	30abf991ac17c18679ab7d633e7549c0ce841920
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNM PALM KDR DYSF EPB41L2	1.07e-05	193	67	5	040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNM PALM KDR DYSF EPB41L2	1.07e-05	193	67	5	e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGM2 SYNM PALM KDR DYSF	1.10e-05	194	67	5	937ee85ffd50869b60f0f6e91017ab77e8b24c0b
ToppCell	Mesenchymal_cells-Arteriolar_fibro.\|World / Lineage and Cell class	HMCN2 ANK2 AEBP1 AHNAK TNMD	1.10e-05	194	67	5	c1e8923a50b4138a1e4c054c0c17b7f7122aa8a9
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYNM PALM KDR DYSF CREM	1.13e-05	195	67	5	36d4a11bc77a4cc97a22525c78ef8359f4a3ca66
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|Epithelial / Condition, Lineage and Cell class	CHL1 TGM2 CLCA4 CMYA5 FER1L6	1.19e-05	197	67	5	78ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA4 AHNAK TPX2 LRRC8A MYBL2	1.19e-05	197	67	5	61c0d78b29dc4ad8a84172cbfcdab03f31351d0e
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGM2 SYNM PALM KDR DYSF	1.19e-05	197	67	5	407231542fa1ffd540dcb61435c0575e71f59725
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNM PALM KDR DYSF EPB41L2	1.21e-05	198	67	5	9ab0db78394e730f6866b2db80047149024ad5f6
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYNM PALM KDR DYSF EPB41L2	1.21e-05	198	67	5	5d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNM PALM KDR DYSF EPB41L2	1.21e-05	198	67	5	e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 KDR GRIN2A DYSF EPB41L2	1.24e-05	199	67	5	dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCell	Healthy/Control\|World / Disease group and Cell class	ARID4B CCDC12 KMT2E RPL4 CREM	1.24e-05	199	67	5	2623c42b3e79e401a485879b52e8bbcbc581544d
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP10 NBPF4 GRIN2A FER1L6	5.75e-05	139	67	4	a1945b07f177cde40e7eea03a19236ce76165857
ToppCell	BL-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MYCL RPGRIP1L SAMD15 FER1L6	9.92e-05	160	67	4	3f737451d5713deed20061aa72a9ef77a9a2bc06
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SFMBT1 SYNM AHNAK CREM	9.92e-05	160	67	4	529034a1101d7772d82f86beb5c6fa9c9dd97067
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGM2 CLCA4 PALM KDR	1.04e-04	162	67	4	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	droplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN8A TPX2 CEP192 MYBL2	1.12e-04	165	67	4	96f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell	Endothelial-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	SYNM PALM KDR EPB41L2	1.17e-04	167	67	4	6a03d16165e0b003092c39972928981abd4a75aa
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	CHL1 SYNM KDR EPB41L2	1.17e-04	167	67	4	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	Int-URO-Lymphocyte-B-B_intermediate\|Int-URO / Disease, Lineage and Cell Type	SFMBT1 ANK2 AEBP1 MACROD2	1.20e-04	168	67	4	5b3fb1fc8fea810c6d4e6feb42c24fb57e8066de
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 XIRP2 CMYA5 RBM20	1.25e-04	170	67	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-MAIT_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GTF3C1 CAMKK1 AAK1 CREM	1.25e-04	170	67	4	059f7ae615342ea19f43b0a405cd7272251a78a9
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 AEBP1 PALM EPB41L2	1.31e-04	172	67	4	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	SYNM PALM KDR DYSF	1.31e-04	172	67	4	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SETD1A TGM2 MACROD2 SAMD15	1.37e-04	174	67	4	59ccc5a82507463e0a316ba6286cb25ec1a4091b
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SETD1A KDR DYSF MYBL2	1.40e-04	175	67	4	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM2 CLCA4 KDR DYSF	1.43e-04	176	67	4	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 XIRP2 CMYA5 RBM20	1.43e-04	176	67	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP2 AHNAK CMYA5 RBM20	1.43e-04	176	67	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SYNM PCLO KDR DYSF	1.53e-04	179	67	4	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SYNM PCLO KDR DYSF	1.53e-04	179	67	4	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHNAK KDR KMT2E EPB41L2	1.56e-04	180	67	4	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHNAK KDR KMT2E EPB41L2	1.56e-04	180	67	4	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SYNM PCLO KDR DYSF	1.59e-04	181	67	4	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 TGM2 LRRC8A KDR	1.59e-04	181	67	4	0756d7d315b8cdd07a3cf6cdfc8a0679786b8e6a
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 TGM2 LRRC8A KDR	1.59e-04	181	67	4	b09947d2d7b21f96d98b87ceb6f467ea329c4092
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	SYNM PCLO KDR DYSF	1.59e-04	181	67	4	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 TGM2 LRRC8A KDR	1.59e-04	181	67	4	3f0d88e9506d66d4e71b88c50d5187302065930f
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 XIRP2 CMYA5 RBM20	1.59e-04	181	67	4	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	DPP10 ANK2 PCLO SCN8A	1.63e-04	182	67	4	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CHL1 KDR GRIN2A EPB41L2	1.63e-04	182	67	4	a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CHL1 HABP4 GPCPD1 EPB41L2	1.63e-04	182	67	4	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	URO-Lymphocyte-T_NK-dnT\|URO / Disease, Lineage and Cell Type	SFMBT1 MACROD2 IFT43 EXOC8	1.63e-04	182	67	4	f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNM PALM KDR EPB41L2	1.66e-04	183	67	4	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	Control-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	CHL1 TGM2 KDR FER1L6	1.66e-04	183	67	4	bdd461349a1ef43a015843937d26e8d3571ecc22
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGM2 SYNM PALM DYSF	1.66e-04	183	67	4	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHL1 ANK2 MACROD2 EPB41L2	1.66e-04	183	67	4	01664fce6b70a02c9d39d747b6a6aabc86d57bc2
ToppCell	(6)_Endothelial-F_(Lymphatics)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SYNM PALM KDR DYSF	1.70e-04	184	67	4	03ea613e00b45c81b752c14505a0538d698f551e
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DPP10 ANK2 CAMKK1 PCLO	1.70e-04	184	67	4	9e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 XIRP2 CMYA5 RBM20	1.70e-04	184	67	4	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 XIRP2 CMYA5 RBM20	1.73e-04	185	67	4	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SYNM PCLO KDR DYSF	1.73e-04	185	67	4	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA4 DPP10 AHNAK CMYA5	1.73e-04	185	67	4	e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	XIRP2 PCLO KDR DYSF	1.73e-04	185	67	4	241ea1e178fffef9e7df971de739e794332d5173
ToppCell	Endothelial-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	SYNM PALM KDR DYSF	1.73e-04	185	67	4	133c9dc64d564dae4aeeeca22f386aa3f13fa980
ToppCell	Endoth-Lymph\|World / shred by cell class for parenchyma	SYNM PALM KDR DYSF	1.73e-04	185	67	4	97a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AHNAK SUPT7L MACROD2 MYBL2	1.77e-04	186	67	4	55b239834b96b1f7787ec77a7d19796d617bbbf0
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNM PALM KDR EPB41L2	1.77e-04	186	67	4	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CHL1 SYNM KDR DYSF	1.77e-04	186	67	4	f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHNAK GPCPD1 PALM KDR	1.77e-04	186	67	4	ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHNAK GPCPD1 PALM KDR	1.77e-04	186	67	4	65e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DPP10 ANK2 PCLO SCN8A	1.77e-04	186	67	4	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHNAK GPCPD1 PALM KDR	1.77e-04	186	67	4	e4f1259725160719e5fd13d76e5a707efed70013
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CHL1 SYNM KDR DYSF	1.77e-04	186	67	4	2b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCell	droplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 PCLO PALM DYSF	1.81e-04	187	67	4	9c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 PCLO PALM DYSF	1.81e-04	187	67	4	9e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	SYNM PALM KDR DYSF	1.81e-04	187	67	4	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ANK2 CMYA5 DYSF RBM20	1.84e-04	188	67	4	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	droplet-Fat-SCAT-30m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM2 SYNM KDR DYSF	1.84e-04	188	67	4	e901a9bdf00b8e91806f445af66647373bf62661
Disease	Neurodevelopmental Disorders	ANK2 SCN8A SRCAP KMT2E	4.78e-05	93	63	4	C1535926
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	DYSF FER1L6	9.36e-05	7	63	2	DOID:11724 (implicated_via_orthology)
Disease	monocyte percentage of leukocytes	ATF7 ARID4B MARK3 AHNAK TPX2 NBPF4 PHLPP1 AKAP13	1.59e-04	731	63	8	EFO_0007989
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 40	KMT2E DHX34	1.60e-04	9	63	2	C4225275
Disease	Mental Retardation, Psychosocial	CHL1 SCN8A GON4L CHD8	2.26e-04	139	63	4	C0025363
Disease	Profound Mental Retardation	CHL1 SCN8A GON4L CHD8	2.26e-04	139	63	4	C0020796
Disease	Mental deficiency	CHL1 SCN8A GON4L CHD8	2.26e-04	139	63	4	C0917816
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	TGM2 AHNAK AKAP13 KDR	2.88e-04	148	63	4	C0279702
Disease	lymphocyte:monocyte ratio	ARID4B MARK3 AHNAK TPX2 PHLPP1	3.79e-04	288	63	5	EFO_0600088
Disease	Intellectual Disability	CHL1 SETD1A SCN8A GON4L CHD8 KMT2E	3.83e-04	447	63	6	C3714756
Disease	epilepsy (implicated_via_orthology)	CHL1 ANK2 SCN8A GRIN2A	4.15e-04	163	63	4	DOID:1826 (implicated_via_orthology)
Disease	Pontoneocerebellar hypoplasia	EXOSC9 PCLO	5.28e-04	16	63	2	cv:C1261175
Disease	Esophageal Neoplasms	TGM2 AKAP13 KDR	6.30e-04	78	63	3	C0014859
Disease	Malignant neoplasm of esophagus	TGM2 AKAP13 KDR	6.30e-04	78	63	3	C0546837
Disease	Colorectal Carcinoma	CHL1 TGM2 ANK2 TPX2 KDR GRIN2A SPAG17	7.30e-04	702	63	7	C0009402
Disease	Adenoid Cystic Carcinoma	ARID4B KAT6A SRCAP	1.29e-03	100	63	3	C0010606
Disease	body weight	SFMBT1 EXOSC9 RPGRIP1L MACROD2 AAK1 GON4L CHD8 CEP192 EPB41L2	1.37e-03	1261	63	9	EFO_0004338
Disease	anterior thigh muscle fat infiltration measurement	HMCN2 DYSF	1.64e-03	28	63	2	EFO_0020936
Disease	Epilepsy	SETD1A SCN8A GRIN2A	1.66e-03	109	63	3	C0014544

Protein segments in the cluster

Peptide	Gene	Start	Entry
NIIPREEKPIEDEIE	ARID4B	446	Q4LE39
DEEEEEVDVTGPIKP	CHD8	596	Q9HCK8
DKVAEDEFDPIPVLI	AAK1	911	Q2M2I8
EVEPEFGTKVEPEFE	AEBP1	1096	Q8IUX7
VERKGEEVEPAPIVD	AKAP13	376	Q12802
EVDIRDPKVDIDVPD	AHNAK	4626	Q09666
TPDIKIKEEEPVEVD	ATF7	101	P17544
LKEEISVLPQEPEED	DPP10	781	Q8N608
ELPEVKEQEVPEDSV	NBPF4	421	Q96M43
EEEDFIVEPDIPELE	RBM20	916	Q5T481
AELVVIEDAAEPKEP	PALM	326	O75781
AFESEKEIELPKEVP	GRSF1	371	Q12849
IDEVEAPEEVEVLEP	MRFAP1L1	6	Q96HT8
APEEVEVLEPEEDFE	MRFAP1L1	11	Q96HT8
VEEDLFNTLPPEVKE	LRRC8A	786	Q8IWT6
EIPPETVTEEEYIDE	ANK2	3876	Q01484
EKIDPLEVEEGDPIV	CHL1	136	O00533
KEISPEVEHIPEIEI	RPGRIP1L	996	Q68CZ1
PPSIENEDLEEVIKV	HMCN2	2451	Q8NDA2
VFPEEPEISEELKDL	CAMKK1	371	Q8N5S9
TEEPEIGNIEKPVEI	METTL14	316	Q9HCE5
VVEEQVLDKEEPLPE	EPB41L2	106	O43491
EESPAKVPELEVEEE	HABP4	271	Q5JVS0
KAEEIIAEAEPPSEV	EXOSC9	311	Q06265
DPEGFEISPEKIIEV	PCLO	1866	Q9Y6V0
QEPDFIDDIEEKTPI	KMT2E	541	Q8IZD2
DDKEDEEIVSLPPVE	MYCLP1	241	P12525
EVPELPLVVEDKVEG	RPL4	146	P36578
EEEEPAVPEVEEEKV	EXOC8	316	Q8IYI6
EEENEEKPLLEVSPE	CRACDL	261	Q6NV74
ELEEQPTREDVKEEP	KAT6A	1331	Q92794
PIIPDLEEVQEEDFV	IFT43	101	Q96FT9
DADPVELFEIPVKEL	GPCPD1	386	Q9NPB8
LVEEEIVELDYPESP	CMYA5	526	Q8N3K9
VDEEIDPIPKVINTD	INTS14	236	Q96SY0
VALPDVEEEEEPPKI	GON4L	1806	Q3T8J9
PIFEEASDVIKEEFP	ERP44	66	Q9BS26
HEEDELKPFVEPELD	MARK3	311	P27448
EEHEVIVSFTPKDPE	CEP192	1706	Q8TEP8
EAAKPEPVIEEVDLA	CCDC12	91	Q8WUD4
DVPGVPKIEEERSEE	CREM	131	Q03060
LEEEEEDTPVSPKEV	DHX34	966	Q14147
TDENVPEPLEEIKLE	SAMD15	321	Q9P1V8
DDKEPLIPIQEEEFI	DYSF	1461	O75923
EQPEVIPLTEDQEEK	MACROD2	366	A1Z1Q3
IVELAEPEEVEVLEP	MRFAP1	6	Q9Y605
EVESFDVPPEIVPEK	FER1L6	461	Q2WGJ9
PEEFSVPFKVEEVED	SYNM	761	O15061
EEEETKPIELPVKEE	SARNP	61	P82979
ELPEVKEQEVPEDSV	NBPF6	421	Q5VWK0
VPPTIKEEENSEEEL	MYBL2	231	P10244
KEEPVSDITFPVSEE	SUPT7L	276	O94864
EEGAEEEPPQVLEIK	SRCAP	366	Q6ZRS2
LEAPEVVVAEAEEPK	SETD1A	1336	O15047
EPDLKDLFITVDEPE	SNX7	26	Q9UNH6
EKKEEEVEPEPVLQE	SPAG17	1201	Q6Q759
IVIDPSVPEDEKIIE	CLCA4	36	Q14CN2
VEIPDPVEAGEEVKV	TGM2	636	P21980
ETVIDTPEDEEIPKV	XIRP2	171	A4UGR9
IKVIPEFSEPEEEID	TNMD	126	Q9H2S6
KEDEEDEEIVSPPPV	MYCL	246	P12524
TIDIKPEVEEVPVEQ	SCN8A	1136	Q9UQD0
DDQFIIPPELEEEVK	PHLPP1	1661	O60346
EILAKVKEEEEEPLP	SFMBT1	246	Q9UHJ3
VKTFEDIPLEEPEVK	KDR	1236	P35968
DDEDEEVISKTVPPV	GTF3C1	346	Q12789
EDEEEDEPVVIKAQP	TPX2	501	Q9ULW0
LEEAPFVIVEDIDPL	GRIN2A	411	Q12879