Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

1.37e-046612GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

2.54e-048612GO:0032453
GeneOntologyBiologicalProcessregulation of early endosome to late endosome transport

DENND10 MAPK1 MAPK3

2.71e-0520613GO:2000641
GeneOntologyBiologicalProcessregulation of Golgi inheritance

MAPK1 MAPK3

5.14e-054612GO:0090170
GeneOntologyBiologicalProcessregulation of telomere capping

MAPK1 MAPK3 RAD50

6.84e-0527613GO:1904353
GeneOntologyBiologicalProcessorganelle inheritance

MAPK1 MAPK3 VPS13B

7.65e-0528613GO:0048308
GeneOntologyBiologicalProcessGolgi inheritance

MAPK1 MAPK3 VPS13B

7.65e-0528613GO:0048313
GeneOntologyBiologicalProcesstelomere maintenance via telomerase

NAT10 MAPK1 MAPK3 RAD50

7.97e-0577614GO:0007004
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

NAT10 MAPK1 MAPK3 RAD50

1.07e-0483614GO:0006278
GeneOntologyBiologicalProcessGolgi organization

DYM ARFGEF1 MAPK1 MAPK3 VPS13B

1.39e-04168615GO:0007030
GeneOntologyBiologicalProcesstelomere maintenance via telomere lengthening

NAT10 MAPK1 MAPK3 RAD50

1.46e-0490614GO:0010833
GeneOntologyBiologicalProcesstrachea formation

MAPK1 MAPK3

1.79e-047612GO:0060440
GeneOntologyBiologicalProcesspositive regulation of macrophage proliferation

MAPK1 MAPK3

1.79e-047612GO:0120041
GeneOntologyBiologicalProcessmetanephros development

APH1B FAT4 CALB1 NF1

1.80e-0495614GO:0001656
GeneOntologyBiologicalProcessperipheral nervous system development

NF1 MAPK1 MAPK3 DMD

2.03e-0498614GO:0007422
GeneOntologyBiologicalProcessregulation of macrophage proliferation

MAPK1 MAPK3

2.38e-048612GO:0120040
GeneOntologyBiologicalProcesstelomere capping

MAPK1 MAPK3 RAD50

2.42e-0441613GO:0016233
GeneOntologyBiologicalProcessnegative regulation of smoothened signaling pathway

TRAF3IP1 PTCH2 IFT122

2.60e-0442613GO:0045879
GeneOntologyBiologicalProcessregulation of telomere maintenance

NAT10 MAPK1 MAPK3 RAD50

3.39e-04112614GO:0032204
GeneOntologyBiologicalProcessmyelination

NF1 SREBF2 MAPK1 MAPK3 TG

3.58e-04206615GO:0042552
GeneOntologyBiologicalProcessendosomal transport

DENND10 ITSN2 MAPK1 MAPK3 VPS53 VPS13B

3.61e-04320616GO:0016197
GeneOntologyBiologicalProcessSchwann cell development

NF1 MAPK1 MAPK3

3.64e-0447613GO:0014044
GeneOntologyBiologicalProcessouter ear morphogenesis

MAPK1 MAPK3

3.81e-0410612GO:0042473
GeneOntologyBiologicalProcessaxon ensheathment

NF1 SREBF2 MAPK1 MAPK3 TG

3.82e-04209615GO:0008366
GeneOntologyBiologicalProcessensheathment of neurons

NF1 SREBF2 MAPK1 MAPK3 TG

3.82e-04209615GO:0007272
GeneOntologyBiologicalProcesspositive regulation of cyclase activity

NF1 MAPK3 LGR5

3.87e-0448613GO:0031281
GeneOntologyBiologicalProcessearly endosome to late endosome transport

DENND10 MAPK1 MAPK3

4.37e-0450613GO:0045022
GeneOntologyBiologicalProcessDNA biosynthetic process

KAT7 NAT10 MAPK1 MAPK3 RAD50

4.63e-04218615GO:0071897
GeneOntologyBiologicalProcesscaveolin-mediated endocytosis

MAPK1 MAPK3

5.57e-0412612GO:0072584
GeneOntologyBiologicalProcessBergmann glial cell differentiation

MAPK1 MAPK3

5.57e-0412612GO:0060020
GeneOntologyBiologicalProcesstrachea morphogenesis

MAPK1 MAPK3

5.57e-0412612GO:0060439
GeneOntologyBiologicalProcessSchwann cell differentiation

NF1 MAPK1 MAPK3

5.79e-0455613GO:0014037
GeneOntologyBiologicalProcessmaturation of SSU-rRNA

UTP4 NAT10 HEATR1

5.79e-0455613GO:0030490
GeneOntologyBiologicalProcessvesicle-mediated transport between endosomal compartments

DENND10 MAPK1 MAPK3

6.10e-0456613GO:0098927
GeneOntologyBiologicalProcessmacrophage proliferation

MAPK1 MAPK3

6.57e-0413612GO:0061517
GeneOntologyBiologicalProcessERBB2-ERBB3 signaling pathway

MAPK1 MAPK3

6.57e-0413612GO:0038133
GeneOntologyBiologicalProcessregulation of DNA biosynthetic process

KAT7 NAT10 MAPK1 MAPK3

7.45e-04138614GO:2000278
GeneOntologyBiologicalProcessregulation of telomere maintenance via telomerase

NAT10 MAPK1 MAPK3

7.47e-0460613GO:0032210
GeneOntologyBiologicalProcessERBB3 signaling pathway

MAPK1 MAPK3

7.65e-0414612GO:0038129
GeneOntologyBiologicalProcesslearning or memory

GIP APH1B CALB1 NF1 MAPK1 VPS13B

8.07e-04373616GO:0007611
GeneOntologyBiologicalProcesslong-term synaptic potentiation

GIP CALB1 NF1 MAPK1

8.73e-04144614GO:0060291
GeneOntologyBiologicalProcessrenal system development

APH1B FAT4 CALB1 NF1 TRAF3IP1 LGR5

9.63e-04386616GO:0072001
GeneOntologyBiologicalProcessregulation of telomere maintenance via telomere lengthening

NAT10 MAPK1 MAPK3

1.12e-0369613GO:1904356
GeneOntologyBiologicalProcessregulation of cyclase activity

NF1 MAPK3 LGR5

1.12e-0369613GO:0031279
GeneOntologyBiologicalProcessstress-activated protein kinase signaling cascade

KAT7 MAPK1 MAPK3

1.12e-0369613GO:0031098
GeneOntologyBiologicalProcesspositive regulation of telomere capping

MAPK1 MAPK3

1.14e-0317612GO:1904355
GeneOntologyBiologicalProcessglial cell development

NF1 MAPK1 MAPK3 DMD

1.20e-03157614GO:0021782
GeneOntologyBiologicalProcessintracellular transport

DENND10 NF1 TRAF3IP1 XPO5 TMEM94 ITSN2 IFT122 MAPK1 MAPK3 BSN VPS53 VPS13B

1.27e-0314966112GO:0046907
GeneOntologyBiologicalProcesspositive regulation of telomere maintenance

MAPK1 MAPK3 RAD50

1.27e-0372613GO:0032206
GeneOntologyBiologicalProcessregulation of Golgi organization

MAPK1 MAPK3

1.28e-0318612GO:1903358
GeneOntologyBiologicalProcessendocrine system development

GIP NF1 MAPK1 MAPK3

1.32e-03161614GO:0035270
GeneOntologyBiologicalProcesssensory organ development

FAT4 CALB1 NF1 TRAF3IP1 IFT122 MAPK1 MAPK3 LGR5

1.33e-03730618GO:0007423
GeneOntologyBiologicalProcessshort-term memory

APH1B CALB1

1.42e-0319612GO:0007614
GeneOntologyBiologicalProcesscardiac neural crest cell differentiation involved in heart development

MAPK1 MAPK3

1.42e-0319612GO:0061307
GeneOntologyBiologicalProcesscardiac neural crest cell development involved in heart development

MAPK1 MAPK3

1.42e-0319612GO:0061308
GeneOntologyBiologicalProcessERK1 and ERK2 cascade

NF1 MAPK1 MAPK3 DMD SLC30A10 FFAR4

1.45e-03418616GO:0070371
GeneOntologyBiologicalProcessear development

FAT4 CALB1 MAPK1 MAPK3 LGR5

1.54e-03285615GO:0043583
GeneOntologyBiologicalProcesscognition

GIP APH1B CALB1 NF1 MAPK1 VPS13B

1.54e-03423616GO:0050890
GeneOntologyBiologicalProcesstelomere maintenance

NAT10 MAPK1 MAPK3 RAD50

1.54e-03168614GO:0000723
GeneOntologyBiologicalProcessintraciliary anterograde transport

TRAF3IP1 IFT122

1.58e-0320612GO:0035720
GeneOntologyCellularComponentt-UTP complex

UTP4 HEATR1

2.68e-053632GO:0034455
GeneOntologyCellularComponenttrans-Golgi network

TEPSIN ARFGEF1 BSN LGR5 VPS53 VPS13B

3.16e-04306636GO:0005802
GeneOntologyCellularComponenttrans-Golgi network membrane

TEPSIN LGR5 VPS53 VPS13B

3.65e-04112634GO:0032588
GeneOntologyCellularComponentciliary base

TRAF3IP1 IFT122 SPACA9

6.45e-0456633GO:0097546
HumanPhenoHyperlordosis

DYM NF1 MAPK1 DMD HERC1 PLEKHG5 VPS13B

4.98e-05222247HP:0003307
HumanPhenoLordosis

DYM NF1 MAPK1 DMD HERC1 PLEKHG5 VPS13B

4.98e-05222247HP:0002939
HumanPhenoAbnormal morphology of bones of the lower limbs

FAT4 DYM NF1 TRAF3IP1 TTI1 IFT122 MAPK1 VPS13B TG

7.15e-05422249HP:0040066
HumanPhenoCubitus valgus

NF1 KDM5C MAPK1 VPS13B

9.52e-0553244HP:0002967
DomainARM-type_fold

ZYG11A THADA NF1 XPO5 ARFGEF1 TTI1 ZNFX1 ZYG11B FRYL HEATR1

1.58e-073396210IPR016024
Domain-

ZYG11A NF1 XPO5 ARFGEF1 TTI1 ZYG11B FRYL HEATR1

6.84e-072226281.25.10.10
DomainARM-like

ZYG11A NF1 XPO5 ARFGEF1 TTI1 ZYG11B FRYL HEATR1

2.96e-06270628IPR011989
DomainMAPK_ERK1/2

MAPK1 MAPK3

1.08e-052622IPR008349
DomainLeu-rich_rpt_Cys-con_subtyp

FBXL7 FBXL14 NLRC5

3.25e-0519623IPR006553
DomainLRR_CC

FBXL7 FBXL14 NLRC5

3.25e-0519623SM00367
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

6.48e-054622IPR013637
DomainPLU-1

KDM5C KDM5D

6.48e-054622PF08429
Domainzf-C5HC2

KDM5C KDM5D

1.08e-045622PF02928
DomainZnf_C5HC2

KDM5C KDM5D

1.08e-045622IPR004198
DomainZnf_FYVE_PHD

TRIM66 KDM5C KDM5D BSN RUFY4

1.27e-04147625IPR011011
DomainJmjN

KDM5C KDM5D

4.80e-0410622SM00545
DomainJMJN

KDM5C KDM5D

4.80e-0410622PS51183
DomainJmjN

KDM5C KDM5D

4.80e-0410622PF02375
DomainJmjN

KDM5C KDM5D

4.80e-0410622IPR003349
Domain-

ZYG11A FBXL7 FBXL14 NLRC5 ZYG11B LGR5

6.73e-043216263.80.10.10
DomainMAP_kinase_CS

MAPK1 MAPK3

7.00e-0412622IPR003527
DomainMAPK

MAPK1 MAPK3

7.00e-0412622PS01351
DomainL_dom-like

ZYG11A FBXL7 FBXL14 NLRC5 ZYG11B LGR5

7.54e-04328626IPR032675
DomainLRR_6

FBXL7 FBXL14 NLRC5

8.08e-0455623PF13516
Domain-

KDM5C KDM5D

1.11e-03156221.10.150.60
DomainBRIGHT

KDM5C KDM5D

1.11e-0315622SM00501
DomainARID_dom

KDM5C KDM5D

1.11e-0315622IPR001606
DomainARID

KDM5C KDM5D

1.11e-0315622PS51011
DomainARID

KDM5C KDM5D

1.11e-0315622PF01388
DomainZinc_finger_PHD-type_CS

TRIM66 KDM5C KDM5D

1.31e-0365623IPR019786
DomainPHD

TRIM66 KDM5C KDM5D

1.98e-0375623PF00628
DomainLeu-rich_rpt

FBXL7 FBXL14 NLRC5 ZYG11B LGR5

2.04e-03271625IPR001611
DomainZnf_PHD-finger

TRIM66 KDM5C KDM5D

2.30e-0379623IPR019787
DomainJmjC

KDM5C KDM5D

2.85e-0324622PF02373
DomainPHD

TRIM66 KDM5C KDM5D

3.23e-0389623SM00249
DomainZnf_PHD

TRIM66 KDM5C KDM5D

3.44e-0391623IPR001965
DomainZF_PHD_2

TRIM66 KDM5C KDM5D

3.88e-0395623PS50016
DomainZF_PHD_1

TRIM66 KDM5C KDM5D

4.00e-0396623PS01359
DomainENTH_VHS

TEPSIN TTI1

4.16e-0329622IPR008942
DomainJMJC

KDM5C KDM5D

5.04e-0332622PS51184
DomainJmjC_dom

KDM5C KDM5D

5.04e-0332622IPR003347
DomainJmjC

KDM5C KDM5D

5.36e-0333622SM00558
DomainLRR_1

FBXL7 FBXL14 NLRC5 LGR5

6.03e-03219624PF00560
Domain-

KAT7 NAT10

7.80e-03406223.40.630.30
DomainF-box-like

FBXL7 FBXL14

9.38e-0344622PF12937
DomainAcyl_CoA_acyltransferase

KAT7 NAT10

9.79e-0345622IPR016181
PathwayPID_TELOMERASE_PATHWAY

ZNFX1 MAPK1 MAPK3 RAD50

4.55e-0567424M105
PathwayWP_THYROXINE_THYROID_HORMONE_PRODUCTION

MAPK1 MAPK3 TG

5.40e-0525423M39353
PathwayBIOCARTA_PELP1_PATHWAY

MAPK1 MAPK3

8.62e-055422MM1575
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_USP8_TO_EGFR_ERK_ACTH_SIGNALING_PATHWAY

MAPK1 MAPK3

8.62e-055422M49028
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_BRAF_TO_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.62e-055422M49016
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.62e-055422M49004
PathwayWP_TCA_CYCLE_NUTRIENT_USE_AND_INVASIVENESS_OF_OVARIAN_CANCER

MAPK1 MAPK3

8.62e-055422M39621
PathwayBIOCARTA_AGR_PATHWAY

MAPK1 MAPK3 DMD

1.04e-0431423MM1343
PathwayPID_SYNDECAN_2_PATHWAY

NF1 MAPK1 MAPK3

1.26e-0433423M240
PathwayBIOCARTA_AGR_PATHWAY

MAPK1 MAPK3 DMD

1.26e-0433423M6220
PathwayBIOCARTA_SAM68_PATHWAY

MAPK1 MAPK3

1.29e-046422MM1567
PathwayBIOCARTA_SAM68_PATHWAY

MAPK1 MAPK3

1.29e-046422M22052
PathwayBIOCARTA_PELP1_PATHWAY

MAPK1 MAPK3

1.29e-046422M22062
PathwayREACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY

MAPK1 MAPK3

1.29e-046422M27559
PathwayREACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY

MAPK1 MAPK3

1.29e-046422MM15273
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY

MAPK1 MAPK3

1.29e-046422M47766
PathwayKEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING

MAPK1 MAPK3

1.29e-046422M47936
PathwayREACTOME_SIGNALING_BY_NODAL

MAPK1 MAPK3

1.29e-046422MM14517
PathwayREACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS

MAPK1 MAPK3

1.80e-047422MM17070
PathwayREACTOME_SIGNALING_BY_LTK_IN_CANCER

MAPK1 MAPK3

1.80e-047422M48255
PathwayREACTOME_RSK_ACTIVATION

MAPK1 MAPK3

1.80e-047422M27369
PathwayREACTOME_SUPPRESSION_OF_APOPTOSIS

MAPK1 MAPK3

1.80e-047422M29815
PathwayBIOCARTA_STAT3_PATHWAY

MAPK1 MAPK3

2.40e-048422MM1576
PathwayBIOCARTA_STAT3_PATHWAY

MAPK1 MAPK3

2.40e-048422M22063
PathwayREACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS

MAPK1 MAPK3

2.40e-048422M48010
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROK2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

2.40e-048422M47642
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PROKR2_TO_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

2.40e-048422M47643
PathwayKEGG_MEDICUS_REFERENCE_PROK_PRKR_GI_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

3.08e-049422M47641
PathwayPID_PS1_PATHWAY

APH1B MAPK1 MAPK3

3.41e-0446423M70
PathwayREACTOME_SIGNAL_ATTENUATION

MAPK1 MAPK3

3.84e-0410422M14236
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

3.84e-0410422M47374
PathwayKEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

3.84e-0410422M47420
PathwayREACTOME_FORMATION_OF_APOPTOSOME

MAPK1 MAPK3

3.84e-0410422MM14485
PathwayREACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS

MAPK1 MAPK3

3.84e-0410422MM15135
PathwayREACTOME_SIGNAL_ATTENUATION

MAPK1 MAPK3

3.84e-0410422MM15440
PathwayKEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

3.84e-0410422M47735
PathwayREACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS

MAPK1 MAPK3

3.84e-0410422M13962
PathwayWP_SYNAPTIC_SIGNALING_ASSOCIATED_WITH_AUTISM_SPECTRUM_DISORDER

NF1 MAPK1 MAPK3

4.37e-0450423M39822
PathwayKEGG_MEDICUS_VARIANT_RET_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

4.69e-0411422M47370
PathwayKEGG_MEDICUS_VARIANT_TRK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

4.69e-0411422M47371
PathwayWP_NPHP1_DELETION_SYNDROME

MAPK1 MAPK3

4.69e-0411422M48099
PathwayREACTOME_FORMATION_OF_APOPTOSOME

MAPK1 MAPK3

4.69e-0411422M41721
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

5.61e-0412422M47369
PathwayKEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

5.61e-0412422M47597
PathwayREACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION

GIP FFAR4

5.61e-0412422MM15036
PathwayWP_BILE_ACID_SYNTHESIS_AND_ENTEROHEPATIC_CIRCULATION

MAPK1 MAPK3

5.61e-0412422M39802
PathwayREACTOME_CYTOCHROME_C_MEDIATED_APOPTOTIC_RESPONSE

MAPK1 MAPK3

5.61e-0412422MM14487
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

5.61e-0412422M47815
PathwayREACTOME_ERKS_ARE_INACTIVATED

MAPK1 MAPK3

6.62e-0413422MM14811
PathwayKEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

6.62e-0413422M47589
PathwayREACTOME_ERKS_ARE_INACTIVATED

MAPK1 MAPK3

6.62e-0413422M8410
PathwayBIOCARTA_CDK5_PATHWAY

MAPK1 MAPK3

6.62e-0413422M89
PathwayREACTOME_CYTOCHROME_C_MEDIATED_APOPTOTIC_RESPONSE

MAPK1 MAPK3

6.62e-0413422M26907
PathwayWP_MFAP5MEDIATED_OVARIAN_CANCER_CELL_MOTILITY_AND_INVASIVENESS

MAPK1 MAPK3

6.62e-0413422M39463
PathwayWP_OSTEOPONTIN_SIGNALING

MAPK1 MAPK3

6.62e-0413422M39603
PathwayREACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING

MAPK1 MAPK3

6.62e-0413422M975
PathwayPID_ATF2_PATHWAY

NF1 MAPK1 MAPK3

7.12e-0459423M166
PathwayREACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL

UTP4 NAT10 HEATR1

7.48e-0460423M27613
PathwayBIOCARTA_BARR_MAPK_PATHWAY

MAPK1 MAPK3

7.71e-0414422M668
PathwayKEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

7.71e-0414422M47364
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

7.71e-0414422M47365
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

7.71e-0414422M47366
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

7.71e-0414422M47378
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

7.71e-0414422M47383
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

7.71e-0414422M47384
PathwayREACTOME_PROLONGED_ERK_ACTIVATION_EVENTS

MAPK1 MAPK3

7.71e-0414422M622
PathwayREACTOME_PROLONGED_ERK_ACTIVATION_EVENTS

MAPK1 MAPK3

7.71e-0414422MM14667
PathwayBIOCARTA_CDK5_PATHWAY

MAPK1 MAPK3

7.71e-0414422MM1457
PathwayREACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION

MAPK1 MAPK3

7.71e-0414422M26983
PathwayBIOCARTA_ERK5_PATHWAY

MAPK1 MAPK3

7.71e-0414422MM1481
PathwayPID_TCR_RAS_PATHWAY

MAPK1 MAPK3

7.71e-0414422M134
PathwayKEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

7.71e-0414422M47488
PathwayPID_S1P_S1P4_PATHWAY

MAPK1 MAPK3

7.71e-0414422M64
PathwayBIOCARTA_BARR_MAPK_PATHWAY

MAPK1 MAPK3

7.71e-0414422MM1489
PathwayBIOCARTA_ERK5_PATHWAY

MAPK1 MAPK3

7.71e-0414422M16811
PathwayBIOCARTA_CDMAC_PATHWAY

MAPK1 MAPK3

8.88e-0415422MM1358
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47367
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47375
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47382
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47380
PathwayKEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47592
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47593
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47640
PathwayPID_ARF6_DOWNSTREAM_PATHWAY

MAPK1 MAPK3

8.88e-0415422M120
PathwayKEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47485
PathwayKEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47473
PathwayKEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47474
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47480
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47495
PathwayKEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47496
PathwayKEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47497
PathwayKEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47472
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47535
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

8.88e-0415422M47531
PathwayREACTOME_SIGNALING_BY_ACTIVIN

MAPK1 MAPK3

8.88e-0415422MM14593
PathwayPID_SMAD2_3PATHWAY

MAPK1 MAPK3

1.01e-0316422M228
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

1.01e-0316422M47363
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

1.01e-0316422M47373
PathwayBIOCARTA_SPRY_PATHWAY

MAPK1 MAPK3

1.01e-0316422MM1500
PathwayKEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY

MAPK1 MAPK3

1.01e-0316422M47381
Pubmed

Neurofibromin (Nf1) is required for skeletal muscle development.

NF1 MAPK1 MAPK3 DMD

5.10e-091264421478499
Pubmed

Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.

NF1 MAPK1 MAPK3

5.94e-09364323221339
Pubmed

Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo.

SREBF2 MAPK1 MAPK3

5.94e-09364314988395
Pubmed

Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers.

MAPK1 MAPK3 DMD

5.94e-09364314718391
Pubmed

ALOX15B controls macrophage cholesterol homeostasis via lipid peroxidation, ERK1/2 and SREBP2.

SREBF2 MAPK1 MAPK3

2.37e-08464338581859
Pubmed

Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade.

SREBF2 MAPK1 MAPK3

2.37e-08464310627507
Pubmed

NF1 tumor suppressor protein and mRNA in skeletal tissues of developing and adult normal mouse and NF1-deficient embryos.

NF1 MAPK1 MAPK3

2.37e-08464315125795
Pubmed

Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1.

CALB1 NF1 MAPK1 MAPK3

3.96e-081964425535838
Pubmed

Neurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ROCK-dependent manner.

NF1 MAPK1 MAPK3

5.93e-08564321903164
Pubmed

Neurofibromatosis type 1 alternative splicing is a key regulator of Ras/ERK signaling and learning behaviors in mice.

NF1 MAPK1 MAPK3

5.93e-08564328934393
Pubmed

Nf1 has an essential role in endothelial cells.

NF1 MAPK1 MAPK3

5.93e-08564312469121
Pubmed

Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy.

MAPK1 MAPK3 DMD

2.07e-07764335618700
Pubmed

The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice.

NF1 MAPK1 MAPK3

2.07e-07764316906226
Pubmed

Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.

CALB1 DMD BSN

3.31e-07864312115694
Pubmed

Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum.

CALB1 MAPK1 MAPK3

4.95e-07964323505473
Pubmed

Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos.

NF1 MAPK1 MAPK3

4.95e-07964326460546
Pubmed

Borealin/CDCA8 deficiency alters thyroid development and results in papillary tumor-like structures.

MAPK1 MAPK3 TG

7.07e-071064337964961
Pubmed

Spatiotemporal Loss of NF1 in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway.

NF1 MAPK1 MAPK3

7.07e-071064330348677
Pubmed

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development.

MAPK1 MAPK3 TG

7.07e-071064318952847
Pubmed

The GDNF target Vsnl1 marks the ureteric tip.

CALB1 MAPK1 MAPK3

1.29e-061264321289216
Pubmed

Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation.

CALB1 DMD BSN

1.68e-061364318641643
Pubmed

Lens induction requires attenuation of ERK signaling by Nf1.

NF1 MAPK1 MAPK3

1.68e-061364321233129
Pubmed

Mutations in PTRH2 cause novel infantile-onset multisystem disease with intellectual disability, microcephaly, progressive ataxia, and muscle weakness.

CALB1 MAPK1 MAPK3

1.68e-061364325574476
Pubmed

Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.

PTCH2 MAPK1 MAPK3 LGR5

1.75e-064764432747435
Pubmed

ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination.

CALB1 MAPK1 MAPK3

2.13e-061464325564653
Pubmed

Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis.

MAPK1 MAPK3 TG

3.27e-061664338750011
Pubmed

Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.

NF1 MAPK1 MAPK3

3.27e-061664328637693
Pubmed

Expression and activation of mitogen-activated protein kinase in the human endometrium during the menstrual cycle.

MAPK1 MAPK3

3.33e-06264216796978
Pubmed

Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein.

MAPK1 MAPK3

3.33e-0626429792705
Pubmed

Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2.

MAPK1 MAPK3

3.33e-06264227564099
Pubmed

A role for ERK2 in reconsolidation of fear memories in mice.

MAPK1 MAPK3

3.33e-06264216504549
Pubmed

MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network.

MAPK1 MAPK3

3.33e-06264237999644
Pubmed

Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.

MAPK1 MAPK3

3.33e-06264218070930
Pubmed

Genistein induces G2/M cell cycle arrest via stable activation of ERK1/2 pathway in MDA-MB-231 breast cancer cells.

MAPK1 MAPK3

3.33e-06264218224451
Pubmed

Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence.

MAPK1 MAPK3

3.33e-06264223993963
Pubmed

Mechanical stress promotes angiogenesis through fibroblast exosomes.

MAPK1 MAPK3

3.33e-06264232962863
Pubmed

Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells.

MAPK1 MAPK3

3.33e-06264219801509
Pubmed

The ERK phosphorylation levels in the amygdala predict anxiety symptoms in humans and MEK/ERK inhibition dissociates innate and learned defensive behaviors in rats.

MAPK1 MAPK3

3.33e-06264234316004
Pubmed

Inhibition of the ERK pathway prevents HIVgp120-induced REM sleep increase.

MAPK1 MAPK3

3.33e-06264211532249
Pubmed

Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling.

MAPK1 MAPK3

3.33e-06264228295277
Pubmed

ERK1/2 controls Na,K-ATPase activity and transepithelial sodium transport in the principal cell of the cortical collecting duct of the mouse kidney.

MAPK1 MAPK3

3.33e-06264215456767
Pubmed

Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells.

MAPK1 MAPK3

3.33e-06264212810726
Pubmed

Identification of a JAK2-independent pathway regulating growth hormone (GH)-stimulated p44/42 mitogen-activated protein kinase activity. GH activation of Ral and phospholipase D is Src-dependent.

MAPK1 MAPK3

3.33e-06264212218045
Pubmed

Long non-coding RNA Gm2199 rescues liver injury and promotes hepatocyte proliferation through the upregulation of ERK1/2.

MAPK1 MAPK3

3.33e-06264229789577
Pubmed

Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation.

MAPK1 MAPK3

3.33e-06264227528403
Pubmed

Activation of spinal extracellular signal-regulated kinases (ERK) 1/2 is associated with the development of visceral hyperalgesia of the bladder.

MAPK1 MAPK3

3.33e-06264221705143
Pubmed

ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis.

MAPK1 MAPK3

3.33e-06264216081808
Pubmed

Differential pathways of angiotensin II-induced extracellularly regulated kinase 1/2 phosphorylation in specific cell types: role of heparin-binding epidermal growth factor.

MAPK1 MAPK3

3.33e-06264215143154
Pubmed

Ajoene-induced cell death in human promyeloleukemic cells does not require JNK but is amplified by the inhibition of ERK.

MAPK1 MAPK3

3.33e-06264212555071
Pubmed

ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer.

MAPK1 MAPK3

3.33e-06264225085753
Pubmed

ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation.

MAPK1 MAPK3

3.33e-06264220840867
Pubmed

ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice.

MAPK1 MAPK3

3.33e-06264219286961
Pubmed

Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling.

MAPK1 MAPK3

3.33e-06264219147767
Pubmed

Anaplasma phagocytophilum AptA modulates Erk1/2 signalling.

MAPK1 MAPK3

3.33e-06264220716207
Pubmed

Leukaemia inhibitory factor mediated proliferation of HTR-8/SVneo trophoblast cells is dependent on activation of extracellular signal-regulated kinase 1/2.

MAPK1 MAPK3

3.33e-06264221635820
Pubmed

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo.

MAPK1 MAPK3

3.33e-06264217709754
Pubmed

Cholesterol affects gene expression of the Jun family in colon carcinoma cells using different signaling pathways.

MAPK1 MAPK3

3.33e-06264223643895
Pubmed

A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses.

MAPK1 MAPK3

3.33e-06264228986121
Pubmed

Calcitonin targets extracellular signal-regulated kinase signaling pathway in human cancers.

MAPK1 MAPK3

3.33e-06264218055485
Pubmed

Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer.

MAPK1 MAPK3

3.33e-06264232444778
Pubmed

Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells.

MAPK1 MAPK3

3.33e-06264215322023
Pubmed

MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo.

MAPK1 MAPK3

3.33e-06264215096454
Pubmed

Both ERK1 and ERK2 are required for enterovirus 71 (EV71) efficient replication.

MAPK1 MAPK3

3.33e-06264225803100
Pubmed

Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation.

MAPK1 MAPK3

3.33e-06264220404333
Pubmed

Desialylation of glycoconjugates on the surface of monocytes activates the extracellular signal-related kinases ERK 1/2 and results in enhanced production of specific cytokines.

MAPK1 MAPK3

3.33e-06264214634064
Pubmed

Deletion of ERK1 and ERK2 in the CNS causes cortical abnormalities and neonatal lethality: Erk1 deficiency enhances the impairment of neurogenesis in Erk2-deficient mice.

MAPK1 MAPK3

3.33e-06264221248139
Pubmed

FasL expression in cardiomyocytes activates the ERK1/2 pathway, leading to dilated cardiomyopathy and advanced heart failure.

MAPK1 MAPK3

3.33e-06264226566650
Pubmed

[Effect of ERK1/2 signal pathway on the proliferation of lung fibroblast activated by SiOâ‚‚].

MAPK1 MAPK3

3.33e-06264221126445
Pubmed

Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.

MAPK1 MAPK3

3.33e-06264217297454
Pubmed

Stimulus-coupled spatial restriction of extracellular signal-regulated kinase 1/2 activity contributes to the specificity of signal-response pathways.

MAPK1 MAPK3

3.33e-06264215542825
Pubmed

Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2.

MAPK1 MAPK3

3.33e-06264215721302
Pubmed

Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium.

MAPK1 MAPK3

3.33e-06264226046303
Pubmed

Vasoconstrictor effects of insulin in skeletal muscle arterioles are mediated by ERK1/2 activation in endothelium.

MAPK1 MAPK3

3.33e-06264215059773
Pubmed

Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation.

MAPK1 MAPK3

3.33e-06264217212589
Pubmed

Porcine reproductive and respiratory syndrome virus replication is suppressed by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway.

MAPK1 MAPK3

3.33e-06264220540975
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

3.33e-06264210441747
Pubmed

[The role of extracellular signal regulated kinase 1/2 in mediating osteodifferentiation of human periodontal ligament cells induced by cyclic stretch].

MAPK1 MAPK3

3.33e-06264229188650
Pubmed

Modulation of agrin-induced acetylcholine receptor clustering by extracellular signal-regulated kinases 1 and 2 in cultured myotubes.

MAPK1 MAPK3

3.33e-06264220696763
Pubmed

Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/ p44 and PI3 kinase pathways.

MAPK1 MAPK3

3.33e-06264215132979
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

3.33e-06264216416087
Pubmed

Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation.

MAPK1 MAPK3

3.33e-06264219619605
Pubmed

Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation.

MAPK1 MAPK3

3.33e-06264220368360
Pubmed

ATP-mediated Erk1/2 activation stimulates bacterial capture by filopodia, which precedes Shigella invasion of epithelial cells.

MAPK1 MAPK3

3.33e-06264221669399
Pubmed

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

MAPK1 MAPK3

3.33e-06264216805921
Pubmed

Protective effects of ginsenosides against Bisphenol A-induced cytotoxicity in 15P-1 Sertoli cells via extracellular signal-regulated kinase 1/2 signalling and antioxidant mechanisms.

MAPK1 MAPK3

3.33e-06264222269103
Pubmed

The dopamine-somatostatin chimeric compound BIM-23A760 exerts antiproliferative and cytotoxic effects in human non-functioning pituitary tumors by activating ERK1/2 and p38 pathways.

MAPK1 MAPK3

3.33e-06264219619936
Pubmed

The role of erk1 and erk2 in multiple stages of T cell development.

MAPK1 MAPK3

3.33e-06264216226508
Pubmed

The anti-adipogenic effect of angiotensin II on human preadipose cells involves ERK1,2 activation and PPARG phosphorylation.

MAPK1 MAPK3

3.33e-06264220453075
Pubmed

Bovine colostrum promotes growth and migration of the human keratinocyte HaCaT cell line.

MAPK1 MAPK3

3.33e-06264219919532
Pubmed

Ceramide 1-phosphate stimulates macrophage proliferation through activation of the PI3-kinase/PKB, JNK and ERK1/2 pathways.

MAPK1 MAPK3

3.33e-06264218234473
Pubmed

Biphasic activation of extracellular signal-regulated kinase (ERK) 1/2 in epidermal growth factor (EGF)-stimulated SW480 colorectal cancer cells.

MAPK1 MAPK3

3.33e-06264226879318
Pubmed

Involvement of mitogen-activated protein kinases in the signal transduction pathway of bone marrow-derived macrophage activation in response to in vitro treatment with thymosin alpha 1.

MAPK1 MAPK3

3.33e-06264211789669
Pubmed

ERK1/2 regulates two sequential steps promoting monocyte survival to peroxynitrite.

MAPK1 MAPK3

3.33e-06264216998804
Pubmed

Dual roles of ERK1/2 in cellular senescence induced by excess thymidine in HeLa cells.

MAPK1 MAPK3

3.33e-06264227443255
Pubmed

Endoplasmic Reticulum Stress Induction and ERK1/2 Activation Contribute to Nefazodone-Induced Toxicity in Hepatic Cells.

MAPK1 MAPK3

3.33e-06264227613715
Pubmed

OspF directly attenuates the activity of extracellular signal-regulated kinase during invasion by Shigella flexneri in human dendritic cells.

MAPK1 MAPK3

3.33e-06264218378312
Pubmed

ERK1/2 activity contributes to gemcitabine resistance in pancreatic cancer cells.

MAPK1 MAPK3

3.33e-06264223569008
Pubmed

Gambogenic acid induced mitochondrial-dependent apoptosis and referred to phospho-Erk1/2 and phospho-p38 MAPK in human hepatoma HepG2 cells.

MAPK1 MAPK3

3.33e-06264222222560
Pubmed

Resveratrol reverses hydrogen peroxide-induced proliferative effects in human coronary smooth muscle cells: a novel signaling mechanism.

MAPK1 MAPK3

3.33e-06264218164958
Pubmed

Phenotype of neurons in the nucleus of the solitary tract that express CCK-induced activation of the ERK signaling pathway.

MAPK1 MAPK3

3.33e-06264219176891
InteractionGPR17 interactions

THADA DYM XPO5 COQ8B ARFGEF1 TTI1 HEATR1 VPS53

2.40e-06283628int:GPR17
InteractionVSIG2 interactions

THADA DYM XPO5 TTI1

2.74e-0632624int:VSIG2
InteractionFPR1 interactions

THADA DYM XPO5 COQ8B ARFGEF1 TTI1

5.97e-06147626int:FPR1
InteractionCD40 interactions

THADA DYM XPO5 ARFGEF1 TTI1 HEATR1

7.51e-06153626int:CD40
InteractionEFNA4 interactions

THADA DYM NF1 XPO5 COQ8B TTI1 VPS53

8.53e-06239627int:EFNA4
InteractionGPR182 interactions

THADA DYM XPO5 COQ8B SREBF2 ARFGEF1 TTI1 HEATR1 VPS53

9.89e-06455629int:GPR182
InteractionCD70 interactions

THADA DYM XPO5 COQ8B TTI1 HEATR1

1.20e-05166626int:CD70
InteractionP2RY8 interactions

THADA DYM COQ8B ARFGEF1 TTI1 HEATR1

1.84e-05179626int:P2RY8
InteractionP2RY10 interactions

THADA DYM COQ8B TTI1 HEATR1

1.87e-05106625int:P2RY10
InteractionF2RL1 interactions

THADA DYM XPO5 COQ8B TTI1 HEATR1

2.02e-05182626int:F2RL1
InteractionSIGLECL1 interactions

THADA DYM NF1 ARFGEF1 TTI1

2.54e-05113625int:SIGLECL1
InteractionPROKR1 interactions

THADA TTI1 HEATR1

3.54e-0521623int:PROKR1
InteractionHCST interactions

THADA DYM NF1 XPO5 COQ8B SREBF2

3.94e-05205626int:HCST
InteractionTRIM16 interactions

ARFGEF1 MAPK1 MAPK3 RAD50

3.96e-0562624int:TRIM16
InteractionTPST2 interactions

THADA DYM NF1 ZYG11B HEATR1

3.98e-05124625int:TPST2
InteractionLINC01588 interactions

FAT4 KDM5C VPS13B

4.10e-0522623int:LINC01588
InteractionFAM234A interactions

THADA NF1 ARFGEF1 TTI1 HEATR1

4.29e-05126625int:FAM234A
InteractionOPALIN interactions

THADA DYM NF1 XPO5 ARFGEF1 HEATR1

4.39e-05209626int:OPALIN
InteractionIGHM interactions

DDX31 SREBF2 ARFGEF1 VPS13B ZNF574

4.98e-05130625int:IGHM
InteractionKLHL14 interactions

KLHL28 ZNFX1 IFT122 HERC1

5.07e-0566624int:KLHL14
InteractionC4orf36 interactions

MAPK1 MAPK3

5.57e-054622int:C4orf36
InteractionMGARP interactions

THADA COQ8B ARFGEF1 TTI1 ZYG11B HEATR1

6.14e-05222626int:MGARP
InteractionMFSD4A interactions

THADA XPO5 COQ8B ARFGEF1 TTI1 HEATR1

6.61e-05225626int:MFSD4A
InteractionEFNB1 interactions

THADA DYM NF1 ARFGEF1 TTI1 HEATR1

1.31e-04255626int:EFNB1
InteractionTRRAP interactions

FAT4 FBXL7 DSC1 XPO5 KDM5C SREBF2 TTI1 HEATR1 DMD RAD50

1.37e-047906210int:TRRAP
InteractionZUP1 interactions

NF1 DSC1 FRYL VPS53 RAD50

1.97e-04174625int:ZUP1
InteractionPAGE1 interactions

TMEM60 UTP4 DMD

2.00e-0437623int:PAGE1
InteractionNPTN interactions

THADA XPO5 COQ8B ARFGEF1 TTI1 HEATR1

2.10e-04278626int:NPTN
InteractionDGCR2 interactions

DYM NF1 XPO5 ARFGEF1 HEATR1

2.36e-04181625int:DGCR2
InteractionGPR45 interactions

THADA XPO5 COQ8B ARFGEF1 TTI1 HEATR1

3.16e-04300626int:GPR45
InteractionVIPR2 interactions

THADA DYM XPO5 COQ8B HEATR1

3.26e-04194625int:VIPR2
InteractionDENND10P1 interactions

DENND10 DENND10P1

3.31e-049622int:DENND10P1
InteractionSTAB2 interactions

MAPK1 MAPK3

3.31e-049622int:STAB2
InteractionTATDN3 interactions

ARFGEF1 RAD50

3.31e-049622int:TATDN3
InteractionIRX2 interactions

MAPK1 MAPK3

3.31e-049622int:IRX2
InteractionVPS52 interactions

TRIM66 SREBF2 HEATR1 MAPK3 VPS53

3.33e-04195625int:VPS52
InteractionCOMTD1 interactions

THADA DYM XPO5 TTI1 HEATR1

3.74e-04200625int:COMTD1
InteractionSGCA interactions

XPO5 ARFGEF1 HEATR1 DMD

4.07e-04113624int:SGCA
InteractionVIPR1 interactions

THADA DYM XPO5 COQ8B TTI1

4.19e-04205625int:VIPR1
InteractionC3orf18 interactions

THADA DYM NF1 TTI1

4.35e-04115624int:C3orf18
InteractionSOS1 interactions

ITSN2 MAPK1 MAPK3 DMD

4.64e-04117624int:SOS1
InteractionTNFSF13B interactions

DYM NF1 XPO5 HEATR1

4.95e-04119624int:TNFSF13B
InteractionZCCHC4 interactions

MAPK1 MAPK3

5.03e-0411622int:ZCCHC4
Cytoband10q23.33

FRA10AC1 PIPSL FFAR4

4.28e-062363310q23.33
Cytoband12p13.33

NRIP2 FBXL14

3.12e-041963212p13.33
GeneFamilyZYG11 cell cycle regulator family

ZYG11A ZYG11B

1.58e-0534226
GeneFamilyMitogen-activated protein kinases

MAPK1 MAPK3

4.04e-0413422651
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

5.43e-0415422418
GeneFamilyF-box and leucine rich repeat proteins

FBXL7 FBXL14

1.08e-0321422558
GeneFamilyPHD finger proteins

TRIM66 KDM5C KDM5D

1.19e-039042388
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

TRAF3IP1 IFT122

1.41e-0324422615
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5C KDM5D

1.41e-0324422485
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

HEATR1 KDM5D

6.25e-0351422870
GeneFamilyX-linked mental retardation|Angiotensin receptors

KDM5C DMD

6.73e-0353422103
CoexpressionGSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN

NRIP2 TEPSIN TMEM94 GIMAP2 NLRC5 MED13L

7.50e-06195636M7410
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

ZYG11A FRA10AC1 THADA DYM UTP4 HEATR1 RAD50

6.08e-06243617gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_1000
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM94 SREBF2 TTI1 FRYL HERC1 BSN

1.58e-07174626f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DYM NF1 DMD HERC1 MED13L VPS13B

3.47e-0719962694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARFGEF1 NLRC5 FRYL HERC1 VPS13B

8.49e-06199625f0b0097df0026496470a80d8cc9375ffd8389b00
DrugPhenylthiourea

MAPK1 MAPK3 TAS2R38 TG

4.89e-0814624ctd:D010670
DrugNIH-3

MAPK1 MAPK3 BSN TG

1.87e-0719624CID009822007
DrugAG 127

MAPK1 MAPK3

7.30e-062622ctd:C069028
DrugN-acetyl glycine cysteine amide

MAPK1 MAPK3

7.30e-062622ctd:C510898
DrugN-acetyl-Cys-Gly-Pro-Cys-amide

MAPK1 MAPK3

7.30e-062622ctd:C510899
DrugNF023

MAPK1 MAPK3

7.30e-062622ctd:C105374
Drugtyrphostin 51

MAPK1 MAPK3

7.30e-062622ctd:C118515
Drugcysteinyl-leukotriene

MAPK1 MAPK3

7.30e-062622ctd:C112381
DrugNP00111

MAPK1 MAPK3

7.30e-062622ctd:C530042
Drugsubstance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)-

MAPK1 MAPK3

7.30e-062622ctd:C496429
Drug7-methyljuglone

MAPK1 MAPK3

7.30e-062622ctd:C517013
Drugsodium tetrasulfide

MAPK1 MAPK3

7.30e-062622ctd:C519323
DrugL 759656

MAPK1 MAPK3

7.30e-062622ctd:C118949
Drug2,2',4,4',5,5'-hexabrominated diphenyl ether

MAPK1 MAPK3

7.30e-062622ctd:C478854
DrugCGP 56999A

MAPK1 MAPK3

7.30e-062622ctd:C102659
DrugL 709049

SREBF2 MAPK1 MAPK3

8.55e-0615623ctd:C096429
DrugSulfanilamide [63-74-1]; Up 200; 23.2uM; HL60; HT_HG-U133A

ZNF280A CALB1 FBXL7 NF1 TRAF3IP1 SPACA9

1.69e-051996262709_UP
DrugPyridazines

MAPK1 MAPK3

2.18e-053622ctd:D011724
Drug3,5-diiodothyropropionic acid

MAPK1 MAPK3

2.18e-053622ctd:C082182
DrugPQ 401

MAPK1 MAPK3

2.18e-053622ctd:C569479
DrugSB 258585

MAPK1 MAPK3

2.18e-053622ctd:C418570
Drugcassine

MAPK1 MAPK3

2.18e-053622ctd:C426663
Drugmanganese(III) acetate dihydrate

MAPK1 MAPK3

2.18e-053622ctd:C521134
DrugNipaam-ntbam copolymer

MAPK1 MAPK3

2.18e-053622CID003080965
Drugconnective tissue-activating peptide

MAPK1 MAPK3

2.18e-053622ctd:C009862
Drugspectaline

MAPK1 MAPK3

2.18e-053622ctd:C480880
Drugdelta(4)-tibolone

MAPK1 MAPK3

2.18e-053622ctd:C485706
Drugp38alpha inhibitor CMPD1

MAPK1 MAPK3

2.18e-053622ctd:C492719
DrugOR486

MAPK1 MAPK3

2.18e-053622ctd:C057726
DrugGW2974

MAPK1 MAPK3

2.18e-053622ctd:C506645
Drugkaempferol-7-methyl ether

MAPK1 MAPK3

2.18e-053622ctd:C541117
DrugtPA stop

MAPK1 MAPK3

2.18e-053622ctd:C115645
DrugLBT 613

MAPK1 MAPK3

2.18e-053622ctd:C514877
DrugAAL 881

MAPK1 MAPK3

2.18e-053622ctd:C514876
DrugNGB 2904

MAPK1 MAPK3

2.18e-053622ctd:C116818
Drugwogonoside

MAPK1 MAPK3

2.18e-053622ctd:C473995
DrugGinkgolides

MAPK1 MAPK3

2.18e-053622ctd:D046934
Drug19-epi-okadaic acid

MAPK1 MAPK3

2.18e-053622ctd:C522300
Drugalpha-methyl-4-carboxyphenylglycine

MAPK1 MAPK3

2.18e-053622ctd:C079694
Drug5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole

MAPK1 MAPK3

2.18e-053622ctd:C534240
DrugYM-254890

MAPK1 MAPK3

2.18e-053622ctd:C475455
Drugpoly(N-isopropylacrylamide-N-tert-butylacrylamide)copolymer

MAPK1 MAPK3

2.18e-053622ctd:C079805
Drugcapsanthin

MAPK1 MAPK3

2.18e-053622ctd:C006889
Drughispidulin

MAPK1 MAPK3

2.18e-053622ctd:C055957
Drugbromoxynil octanoate

MAPK1 MAPK3

2.18e-053622ctd:C028382
DrugML 204

MAPK1 MAPK3

2.18e-053622ctd:C567966
Drughwanggunchungyitang

MAPK1 MAPK3

2.18e-053622ctd:C539018
DrugBPC96 peptide

MAPK1 MAPK3

2.18e-053622ctd:C555919
DrugN,N''-1,4-butanediylbis(N'-(3-isothiocyanatophenyl))thiourea

MAPK1 MAPK3

2.18e-053622ctd:C541384
DrugPhosphatidylinositols

MAPK1 MAPK3 HERC1

3.28e-0523623ctd:D010716
Drugisosalipurposide

MAPK1 MAPK3

4.36e-054622ctd:C027321
Drugdiacetylbis(4-methylthiosemicarbazonato)copper(II)

MAPK1 MAPK3

4.36e-054622ctd:C570445
Drugneurotropin

MAPK1 MAPK3

4.36e-054622ctd:C010491
DrugN-(4-chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl)-2-hydroxybenzamide

MAPK1 MAPK3

4.36e-054622ctd:C481448
Drug2-(2-oxo-2-((3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy)aminoethyl)phosphonic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester sodium

MAPK1 MAPK3

4.36e-054622ctd:C436083
Drug2,3,4,2',3',4'-hexachlorobiphenyl

MAPK1 MAPK3

4.36e-054622ctd:C014218
Drug3-(phenylsulfonyl)-4-(2-(4-(2-(3,7,11-trimethyldodeca-2,6,10-trienylthio)benzoyl)piperazin-1-yl)ethoxy)-1,2,5-oxadiazole-2-oxide

MAPK1 MAPK3

4.36e-054622ctd:C559860
DrugPurvalanol

MAPK1 MAPK3

4.36e-054622DB02733
Drugazalanstat

MAPK1 MAPK3

4.36e-054622ctd:C082410
DrugPractolol

MAPK1 MAPK3

4.36e-054622ctd:D011217
DrugDmt-NMe-Ala-Aba-Gly-NH2

MAPK1 MAPK3

4.36e-054622ctd:C569763
Drugmethyl 3, 5-O-dicaffeoylquinate

MAPK1 MAPK3

4.36e-054622ctd:C538691
Drug1,4,5,8-naphthalenetetracarboxylic diimide

MAPK1 MAPK3

4.36e-054622ctd:C429685
DrugO(2)-(2,4-dinitrophenyl) 1-(4-(N,N-diethylcarboxamido)piperazin-1-yl)diazen-1-ium 1,2-diolate

MAPK1 MAPK3

4.36e-054622ctd:C495194
Drug3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridine

MAPK1 MAPK3

4.36e-054622ctd:C423582
Drugmitonafide

MAPK1 MAPK3

4.36e-054622ctd:C019215
Drug4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate)

MAPK1 MAPK3

4.36e-054622ctd:C110258
Drugthunberginol A

MAPK1 MAPK3

4.36e-054622ctd:C079055
Drug7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester

MAPK1 MAPK3

4.36e-054622ctd:C117789
Drugphenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide

MAPK1 MAPK3

4.36e-054622ctd:C049352
Drugamosulalol

MAPK1 MAPK3

4.36e-054622ctd:C032473
Drug1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine

MAPK1 MAPK3

4.36e-054622ctd:C107238
Drugerigeroflavanone

MAPK1 MAPK3

4.36e-054622ctd:C529414
DrugJTE 907

MAPK1 MAPK3

4.36e-054622ctd:C422645
DrugPD 166285

MAPK1 MAPK3

4.36e-054622ctd:C109647
Drug2,5,3'-trichlorobiphenyl

MAPK1 MAPK3

4.36e-054622ctd:C091160
Drugtrimethyltin hydroxide

MAPK1 MAPK3

4.36e-054622ctd:C037718
Drugbovine serum albumin-corticosterone conjugate

MAPK1 MAPK3

4.36e-054622ctd:C439264
DrugImines

MAPK1 MAPK3

4.36e-054622ctd:D007097
Drug3',4'-dihydroxy-4-monochlorobiphenyl

MAPK1 MAPK3

4.36e-054622ctd:C543847
Drugpamoic acid

MAPK1 MAPK3

4.36e-054622ctd:C004368
Drugcorticosterone-21-hemisuccinate

MAPK1 MAPK3

4.36e-054622ctd:C067957
Drugado-trastuzumab emtansine

MAPK1 MAPK3

4.36e-054622ctd:C550911
DrugThiorphan

MAPK1 MAPK3

7.26e-055622ctd:D015244
DrugWHI P154

MAPK1 MAPK3

7.26e-055622ctd:C113888
Drugpiplartine

MAPK1 MAPK3

7.26e-055622ctd:C479506
DrugGGTI-2133

MAPK1 MAPK3

7.26e-055622ctd:C547856
DrugSR140333B

MAPK1 MAPK3

7.26e-055622ctd:C526005
DrugCP 154526

MAPK1 MAPK3

7.26e-055622ctd:C101628
Drug5-iodo-3-(2-azetidinylmethoxy)pyridine

MAPK1 MAPK3

7.26e-055622ctd:C426745
Drugethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate

MAPK1 MAPK3

7.26e-055622ctd:C559943
DrugZeaxanthins

MAPK1 MAPK3

7.26e-055622ctd:D065146
Drug6,7-dimethoxy-2-phenylquinoxaline

MAPK1 MAPK3

7.26e-055622ctd:C407689
DrugThiamylal

MAPK1 MAPK3

7.26e-055622ctd:D013840
DrugE 3330

MAPK1 MAPK3

7.26e-055622ctd:C075569
Drugtyrphostin AG825

MAPK1 MAPK3

7.26e-055622ctd:C098214
DrugVitamin U

MAPK1 MAPK3

7.26e-055622ctd:D014814
Drugciproxifan

MAPK1 MAPK3

7.26e-055622ctd:C115705
Drugilomastat

MAPK1 MAPK3

7.26e-055622ctd:C119203
DrugBacterial Toxins

MAPK1 MAPK3

7.26e-055622ctd:D001427
Diseaseintellectual disability (implicated_via_orthology)

ZNF280A KDM5C ITSN2 KDM5D

1.69e-0575604DOID:1059 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

2.43e-054602DOID:0060809 (implicated_via_orthology)
DiseaseHypothyroidism

KDM5C SLC30A10

2.43e-054602C0020676
DiseaseCEROID LIPOFUSCINOSIS, NEURONAL, 6

MAPK1 MAPK3

6.07e-056602C1866282
DiseaseStreptococcal pneumonia

MAPK1 MAPK3

6.07e-056602C0155862
Diseaseendometrial adenocarcinoma (is_implicated_in)

MAPK1 MAPK3

8.48e-057602DOID:2870 (is_implicated_in)
Diseaseureteral obstruction (implicated_via_orthology)

MAPK1 MAPK3

1.45e-049602DOID:5199 (implicated_via_orthology)
Diseaseendometrial adenocarcinoma (is_marker_for)

MAPK1 MAPK3

2.21e-0411602DOID:2870 (is_marker_for)
Diseaseautism spectrum disorder (implicated_via_orthology)

ZNF280A KDM5C MAPK1 KDM5D

2.64e-04152604DOID:0060041 (implicated_via_orthology)
DiseaseTrigeminal Neuralgia

MAPK1 MAPK3

2.65e-0412602C0040997
DiseaseSecondary Trigeminal Neuralgia

MAPK1 MAPK3

2.65e-0412602C0393787
DiseaseTrigeminal Neuralgia, Idiopathic

MAPK1 MAPK3

2.65e-0412602C0393786
Diseaseliver cirrhosis (implicated_via_orthology)

UTP4 RAD50

3.13e-0413602DOID:5082 (implicated_via_orthology)
Diseasegastric ulcer (implicated_via_orthology)

MAPK1 MAPK3

3.64e-0414602DOID:10808 (implicated_via_orthology)
Diseasebeta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement

FRA10AC1 FAT4

3.64e-0414602EFO_0004670, EFO_0006794
DiseaseCardiomyopathies, Primary

MAPK1 MAPK3 DMD

3.81e-0469603C0033141
DiseaseMyocardial Diseases, Secondary

MAPK1 MAPK3 DMD

3.81e-0469603C0036529
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

4.79e-0416602DOID:0050888 (implicated_via_orthology)
Diseasepancreatic ductal carcinoma (is_implicated_in)

HEATR1 MAPK3

4.79e-0416602DOID:3587 (is_implicated_in)
DiseaseAstrocytosis

MAPK1 MAPK3

5.42e-0417602C3887640
DiseaseGliosis

MAPK1 MAPK3

5.42e-0417602C0017639
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

HERC1 BSN

6.09e-0418602HP_0002373
DiseaseHypertrophy

MAPK1 MAPK3

6.09e-0418602C0020564
Diseasemonocyte percentage of leukocytes

ZYG11A THADA NF1 ITSN2 ZYG11B MED13L RUFY4

6.88e-04731607EFO_0007989
DiseaseNeoplasm Metastasis

SREBF2 MAPK1 MAPK3 DMD

1.01e-03217604C0027627
DiseaseSepticemia

MAPK1 MAPK3

1.09e-0324602C0036690
DiseaseSepsis

MAPK1 MAPK3

1.09e-0324602C0243026
DiseaseSevere Sepsis

MAPK1 MAPK3

1.09e-0324602C1719672
Diseasenephrotic syndrome (implicated_via_orthology)

ITSN2 COQ8B

1.09e-0324602DOID:1184 (implicated_via_orthology)
DiseaseHead Neoplasms

MAPK1 MAPK3

1.09e-0324602C0018675
DiseaseUpper Aerodigestive Tract Neoplasms

MAPK1 MAPK3

1.09e-0324602C0887900
DiseasePyemia

MAPK1 MAPK3

1.09e-0324602C0034189
DiseaseCancer of Head

MAPK1 MAPK3

1.09e-0324602C0751177
Diseaseobesity (is_marker_for)

GIP MAPK1 MAPK3

1.16e-03101603DOID:9970 (is_marker_for)
DiseaseNeck Neoplasms

MAPK1 MAPK3

1.18e-0325602C0027533
DiseaseCancer of Neck

MAPK1 MAPK3

1.18e-0325602C0746787
Diseasecolon adenocarcinoma (is_implicated_in)

MAPK1 MAPK3

1.28e-0326602DOID:234 (is_implicated_in)
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

GIP MAPK1 MAPK3

1.29e-03105603DOID:9352 (implicated_via_orthology)
Diseasemultiple sclerosis

GIMAP2 NLRC5 MAPK1 MAPK3 PLEKHG5 TG

1.29e-03594606MONDO_0005301
Diseaseeye measurement

TRAF3IP1 HERC1

1.38e-0327602EFO_0004731
DiseaseSubfertility, Female

MAPK1 MAPK3

1.49e-0328602C0341869
DiseaseSterility, Postpartum

MAPK1 MAPK3

1.49e-0328602C0038279
DiseaseFemale sterility

MAPK1 MAPK3

1.49e-0328602C0917730
DiseaseFemale infertility

MAPK1 MAPK3

1.49e-0328602C0021361
Diseasepulmonary hypertension (is_implicated_in)

MAPK1 MAPK3

1.71e-0330602DOID:6432 (is_implicated_in)
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

XPO5 COQ8B

1.71e-0330602C1868672
DiseaseCholestasis, Extrahepatic

MAPK1 MAPK3

1.94e-0332602C0005398

Protein segments in the cluster

PeptideGeneStartEntry
LQCSKCRLQFLTLKE

ZNF280A

451

P59817
RSLKLCLLCQDKNFL

APH1B

236

Q8WW43
NLLLRKCCLTDENKL

DENND10P1

41

Q6NSW5
LFELSCIINRCKLDV

ARFGEF1

1386

Q9Y6D6
LALLVLSLILCNQCR

FAT4

4516

Q6V0I7
ELLACLLDQTNLCRL

GIP

136

P09681
QKALCLDLLSLSAAC

DMD

3116

P11532
LIIRLALAETFCLNC

RAD50

1211

Q92878
QCLLSLLSCLNNLFL

ITSN2

631

Q9NZM3
LLNTTCDLKICDFGL

MAPK1

156

P28482
IYCQNLCLLAKLFLD

KAT7

416

O95251
ELLQIIGKCCLNKLS

TRAF3IP1

106

Q8TDR0
IILCQEKRLQCLSFS

IFT122

446

Q9HBG6
ILLSFIRCLQANLLC

MED13L

56

Q71F56
VVLQNCRCLDLLFLS

ERVS71-1

501

P61550
HELLCSLQKQLLAFC

HERC1

986

Q15751
LLQRLKNCLSEVEAC

KDM5D

801

Q9BY66
LCLNCQTKRLLEGSL

BSN

511

Q9UPA5
VKLRLCQECSIKLNF

FRA10AC1

206

Q70Z53
CLVLNLFCADLLFIS

FFAR4

76

Q5NUL3
LITCLLCVSQKQFFL

FRYL

316

O94915
NLLINTTCDLKICDF

MAPK3

171

P27361
KACGLLNCEAVLQLL

TEPSIN

271

Q96N21
KLRLVCLAAFILQKC

DDX31

491

Q9H8H2
CLGLEQLTLQDCQKL

FBXL14

201

Q8N1E6
LNDLLCLDCLNITRI

NAT10

481

Q9H0A0
CCLGQKQLAILLSLV

NLRC5

1361

Q86WI3
LCKTLQRDCLVLQSF

PIPSL

251

A2A3N6
QCLKDISLFLLLCNV

OTOP2

491

Q7RTS6
AANLLQIKLVLKECC

KLHL28

111

Q9NXS3
CLKGALIKTQLCVLF

GIMAP2

261

Q9UG22
LIKTQLCVLFCIQLF

GIMAP2

266

Q9UG22
ALFIICCLLKVFICQ

DYM

106

Q7RTS9
ECLALNCFNLKRLSL

FBXL7

421

Q9UJT9
ENFLLLFRCQQLKSC

CALB1

86

P05937
DLRNQICFQLLTLCL

COQ8B

341

Q96D53
LVLTLLCDACQKVYL

DSC1

21

Q08554
TKQLILSCLLNICQK

HEATR1

1251

Q9H583
NLLLRKCCLTDENKL

DENND10

41

Q8TCE6
LLMFLDICSELNKLC

SPACA9

66

Q96E40
KHIALLLFTNCILNC

LGR5

766

O75473
CLGLQTLLSLKCCID

NRIP2

241

Q9BQI9
KRQALSNSDCVLLCL

TAS2R38

46

P59533
CLISCSKKRQLLLFQ

UTP4

336

Q969X6
QICSLLKKLFCRIQE

THADA

681

Q6YHU6
DILFLLTCCLNRSAK

THADA

1461

Q6YHU6
LLVCTFLVCALLLLN

PTCH2

971

Q9Y6C5
RLCGCLELLLQFDQK

RUFY4

41

Q6ZNE9
QLLVCNCIFKNTLAI

TGM4

601

P49221
RVIINLFLCCLLNLQ

PLEKHG5

356

O94827
LFLCCLLNLQESGLL

PLEKHG5

361

O94827
LEQKDLLLLCNSPCI

SLC30A10

391

Q6XR72
KNCLLSLCSDRILQD

ZYG11B

426

Q9C0D3
LKLAFCLALCAKLEQ

TMEM60

86

Q9H2L4
KCFLFLLQCQLTLVV

TMEM94

1091

Q12767
LLLYKCSECSQLFQL

ZNF574

211

Q6ZN55
RILLCVLTFLCLSFN

SREBF2

481

Q12772
ENCKLLEILCLLLNE

XPO5

246

Q9HAV4
LLCALTCTFNLKIEG

NF1

1876

P21359
VAKFTLEELCLICNI

VPS53

541

Q5VIR6
SNFLELICQVLRKAC

ZNFX1

181

Q9P2E3
IQFLAQADCKLLECR

VPS13B

2546

Q7Z7G8
KLCFCPLAVLLQALL

TTC37

1476

Q6PGP7
EKLVLSLCCNNLSLP

TRIM66

1051

O15016
ACLSFCQLQKQQILL

TG

91

P01266
ICLNVLIANLEKLCS

ZYG11A

41

Q6WRX3
KIAALKCLQVLLLQC

TTI1

171

O43156
LLQQLKNCLSEAEAC

KDM5C

811

P41229