Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	iron ion binding	CYP4V2 JMJD6 CYP7B1	7.74e-04	166	22	3	GO:0005506
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	CYP4V2 JMJD6 CYP7B1	1.21e-03	194	22	3	GO:0016705
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	CYP4V2 CYP7B1	1.32e-03	49	22	2	GO:0016712
GeneOntologyMolecularFunction	calmodulin binding	ADORA2A MYO7A EEF2K	1.98e-03	230	22	3	GO:0005516
GeneOntologyMolecularFunction	glutamate receptor binding	ADORA2A DLG1	3.56e-03	81	22	2	GO:0035254
GeneOntologyBiologicalProcess	positive regulation of chondrocyte development	HOXD11 HOXA11	3.57e-06	3	23	2	GO:1902761
GeneOntologyBiologicalProcess	regulation of chondrocyte development	HOXD11 HOXA11	3.32e-05	8	23	2	GO:0061181
GeneOntologyBiologicalProcess	branching involved in ureteric bud morphogenesis	HOXD11 HOXA11 DLG1	5.79e-05	68	23	3	GO:0001658
GeneOntologyBiologicalProcess	ureteric bud morphogenesis	HOXD11 HOXA11 DLG1	7.46e-05	74	23	3	GO:0060675
GeneOntologyBiologicalProcess	mesonephric tubule morphogenesis	HOXD11 HOXA11 DLG1	8.72e-05	78	23	3	GO:0072171
GeneOntologyBiologicalProcess	embryonic skeletal joint morphogenesis	HOXD11 HOXA11	9.21e-05	13	23	2	GO:0060272
GeneOntologyBiologicalProcess	cellular response to brain-derived neurotrophic factor stimulus	DLG1 EEF2K	1.07e-04	14	23	2	GO:1990416
GeneOntologyBiologicalProcess	nephron tubule morphogenesis	HOXD11 HOXA11 DLG1	1.21e-04	87	23	3	GO:0072078
GeneOntologyBiologicalProcess	cellular response to calcium ion	EEF2K CRHBP CPNE7	1.25e-04	88	23	3	GO:0071277
GeneOntologyBiologicalProcess	nephron epithelium morphogenesis	HOXD11 HOXA11 DLG1	1.29e-04	89	23	3	GO:0072088
GeneOntologyBiologicalProcess	nephron morphogenesis	HOXD11 HOXA11 DLG1	1.38e-04	91	23	3	GO:0072028
GeneOntologyBiologicalProcess	renal tubule morphogenesis	HOXD11 HOXA11 DLG1	1.47e-04	93	23	3	GO:0061333
GeneOntologyBiologicalProcess	embryonic skeletal joint development	HOXD11 HOXA11	1.60e-04	17	23	2	GO:0072498
GeneOntologyBiologicalProcess	ureteric bud development	HOXD11 HOXA11 DLG1	2.23e-04	107	23	3	GO:0001657
GeneOntologyBiologicalProcess	embryonic skeletal system morphogenesis	HOXD11 HOXA11 DLG1	2.35e-04	109	23	3	GO:0048704
GeneOntologyBiologicalProcess	mesonephric tubule development	HOXD11 HOXA11 DLG1	2.42e-04	110	23	3	GO:0072164
GeneOntologyBiologicalProcess	mesonephric epithelium development	HOXD11 HOXA11 DLG1	2.42e-04	110	23	3	GO:0072163
GeneOntologyBiologicalProcess	nephron tubule development	HOXD11 HOXA11 DLG1	2.42e-04	110	23	3	GO:0072080
GeneOntologyBiologicalProcess	kidney morphogenesis	HOXD11 HOXA11 DLG1	2.48e-04	111	23	3	GO:0060993
GeneOntologyBiologicalProcess	mesonephros development	HOXD11 HOXA11 DLG1	2.62e-04	113	23	3	GO:0001823
GeneOntologyBiologicalProcess	renal tubule development	HOXD11 HOXA11 DLG1	2.83e-04	116	23	3	GO:0061326
GeneOntologyBiologicalProcess	positive regulation of chondrocyte differentiation	HOXD11 HOXA11	3.23e-04	24	23	2	GO:0032332
GeneOntologyBiologicalProcess	animal organ morphogenesis	HOXD11 HOXA11 MYO7A DLG1 CYP7B1 TAB1 LARGE1	3.36e-04	1269	23	7	GO:0009887
GeneOntologyBiologicalProcess	chordate embryonic development	HOXD11 HOXA11 DLG1 SUPT6H TAB1 SEMA4C	3.75e-04	906	23	6	GO:0043009
GeneOntologyBiologicalProcess	nephron epithelium development	HOXD11 HOXA11 DLG1	3.78e-04	128	23	3	GO:0072009
GeneOntologyBiologicalProcess	organ induction	HOXD11 HOXA11	3.80e-04	26	23	2	GO:0001759
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	HOXD11 HOXA11 DLG1 SUPT6H TAB1 SEMA4C	4.29e-04	929	23	6	GO:0009792
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	HOXD11 HOXA11 DLG1 CYP7B1 SEMA4C	5.14e-04	619	23	5	GO:0002009
GeneOntologyBiologicalProcess	embryonic organ morphogenesis	HOXD11 HOXA11 MYO7A DLG1	5.65e-04	351	23	4	GO:0048562
GeneOntologyBiologicalProcess	embryonic skeletal system development	HOXD11 HOXA11 DLG1	5.77e-04	148	23	3	GO:0048706
GeneOntologyBiologicalProcess	regulation of animal organ formation	HOXD11 HOXA11	5.78e-04	32	23	2	GO:0003156
GeneOntologyBiologicalProcess	tube development	SPATA2 HOXD11 HOXA11 JMJD6 DLG1 TAB1 SEMA4C	6.15e-04	1402	23	7	GO:0035295
GeneOntologyBiologicalProcess	synaptic transmission, dopaminergic	ADORA2A CRHBP	6.92e-04	35	23	2	GO:0001963
GeneOntologyBiologicalProcess	kidney development	HOXD11 HOXA11 JMJD6 DLG1	7.03e-04	372	23	4	GO:0001822
GeneOntologyBiologicalProcess	embryo development	HOXD11 HOXA11 MYO7A DLG1 SUPT6H TAB1 SEMA4C	7.13e-04	1437	23	7	GO:0009790
GeneOntologyBiologicalProcess	positive regulation of cartilage development	HOXD11 HOXA11	7.32e-04	36	23	2	GO:0061036
GeneOntologyBiologicalProcess	response to calcium ion	EEF2K CRHBP CPNE7	7.37e-04	161	23	3	GO:0051592
GeneOntologyBiologicalProcess	kidney epithelium development	HOXD11 HOXA11 DLG1	7.50e-04	162	23	3	GO:0072073
GeneOntologyBiologicalProcess	proximal/distal pattern formation	HOXD11 HOXA11	7.74e-04	37	23	2	GO:0009954
GeneOntologyBiologicalProcess	embryonic forelimb morphogenesis	HOXD11 HOXA11	7.74e-04	37	23	2	GO:0035115
GeneOntologyBiologicalProcess	reproductive structure development	SPATA2 HOXA11 DLG1 CYP7B1	7.84e-04	383	23	4	GO:0048608
GeneOntologyBiologicalProcess	response to purine-containing compound	ADORA2A EEF2K CRHBP	8.05e-04	166	23	3	GO:0014074
GeneOntologyBiologicalProcess	renal system development	HOXD11 HOXA11 JMJD6 DLG1	8.07e-04	386	23	4	GO:0072001
GeneOntologyBiologicalProcess	reproductive system development	SPATA2 HOXA11 DLG1 CYP7B1	8.22e-04	388	23	4	GO:0061458
GeneOntologyBiologicalProcess	nephron development	HOXD11 HOXA11 DLG1	9.23e-04	174	23	3	GO:0072006
GeneOntologyBiologicalProcess	specification of animal organ identity	HOXD11 HOXA11	9.50e-04	41	23	2	GO:0010092
GeneOntologyBiologicalProcess	chondrocyte development	HOXD11 HOXA11	9.50e-04	41	23	2	GO:0002063
GeneOntologyBiologicalProcess	positive regulation of animal organ morphogenesis	HOXD11 HOXA11	9.50e-04	41	23	2	GO:0110110
GeneOntologyBiologicalProcess	developmental induction	HOXD11 HOXA11	9.50e-04	41	23	2	GO:0031128
GeneOntologyBiologicalProcess	embryonic morphogenesis	HOXD11 HOXA11 MYO7A DLG1 SEMA4C	9.75e-04	713	23	5	GO:0048598
GeneOntologyBiologicalProcess	appendage morphogenesis	HOXD11 HOXA11 LARGE1	1.10e-03	185	23	3	GO:0035107
GeneOntologyBiologicalProcess	limb morphogenesis	HOXD11 HOXA11 LARGE1	1.10e-03	185	23	3	GO:0035108
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	HOXD11 HOXA11 DLG1 SEMA4C	1.11e-03	421	23	4	GO:0060562
GeneOntologyBiologicalProcess	tissue morphogenesis	HOXD11 HOXA11 DLG1 CYP7B1 SEMA4C	1.22e-03	750	23	5	GO:0048729
GeneOntologyBiologicalProcess	cartilage development involved in endochondral bone morphogenesis	HOXD11 HOXA11	1.25e-03	47	23	2	GO:0060351
GeneOntologyBiologicalProcess	forelimb morphogenesis	HOXD11 HOXA11	1.30e-03	48	23	2	GO:0035136
GeneOntologyBiologicalProcess	branching morphogenesis of an epithelial tube	HOXD11 HOXA11 DLG1	1.34e-03	198	23	3	GO:0048754
GeneOntologyBiologicalProcess	cellular response to cAMP	EEF2K CRHBP	1.58e-03	53	23	2	GO:0071320
GeneOntologyBiologicalProcess	cellular response to metal ion	EEF2K CRHBP CPNE7	1.79e-03	219	23	3	GO:0071248
GeneOntologyBiologicalProcess	eye development	MYO7A JMJD6 DLG1 LARGE1	1.80e-03	480	23	4	GO:0001654
GeneOntologyBiologicalProcess	visual system development	MYO7A JMJD6 DLG1 LARGE1	1.85e-03	483	23	4	GO:0150063
GeneOntologyBiologicalProcess	limb development	HOXD11 HOXA11 LARGE1	1.91e-03	224	23	3	GO:0060173
GeneOntologyBiologicalProcess	appendage development	HOXD11 HOXA11 LARGE1	1.91e-03	224	23	3	GO:0048736
GeneOntologyBiologicalProcess	neuromuscular process	ADORA2A MYO7A LARGE1	1.93e-03	225	23	3	GO:0050905
GeneOntologyBiologicalProcess	cellular response to nerve growth factor stimulus	DLG1 EEF2K	1.96e-03	59	23	2	GO:1990090
GeneOntologyBiologicalProcess	regulation of chondrocyte differentiation	HOXD11 HOXA11	1.96e-03	59	23	2	GO:0032330
GeneOntologyBiologicalProcess	sensory system development	MYO7A JMJD6 DLG1 LARGE1	1.96e-03	491	23	4	GO:0048880
GeneOntologyBiologicalProcess	response to nerve growth factor	DLG1 EEF2K	2.09e-03	61	23	2	GO:1990089
GeneOntologyBiologicalProcess	prostate gland development	HOXA11 CYP7B1	2.16e-03	62	23	2	GO:0030850
GeneOntologyBiologicalProcess	morphogenesis of a branching epithelium	HOXD11 HOXA11 DLG1	2.21e-03	236	23	3	GO:0061138
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	HOXD11 HOXA11 DLG1	2.85e-03	258	23	3	GO:0001763
GeneOntologyBiologicalProcess	bone development	HOXD11 HOXA11 LARGE1	3.04e-03	264	23	3	GO:0060348
GeneOntologyBiologicalProcess	embryonic digit morphogenesis	HOXD11 HOXA11	3.06e-03	74	23	2	GO:0042733
GeneOntologyBiologicalProcess	embryonic organ development	HOXD11 HOXA11 MYO7A DLG1	3.18e-03	561	23	4	GO:0048568
GeneOntologyBiologicalProcess	cell junction assembly	DLG1 EEF2K SEMA4C LARGE1	3.34e-03	569	23	4	GO:0034329
GeneOntologyBiologicalProcess	phagocytosis	ADORA2A MYO7A JMJD6	3.37e-03	274	23	3	GO:0006909
GeneOntologyBiologicalProcess	animal organ formation	HOXD11 HOXA11	3.39e-03	78	23	2	GO:0048645
GeneOntologyBiologicalProcess	skeletal system morphogenesis	HOXD11 HOXA11 DLG1	3.48e-03	277	23	3	GO:0048705
GeneOntologyBiologicalProcess	endochondral bone morphogenesis	HOXD11 HOXA11	3.48e-03	79	23	2	GO:0060350
GeneOntologyBiologicalProcess	urogenital system development	HOXA11 CYP7B1	3.48e-03	79	23	2	GO:0001655
GeneOntologyBiologicalProcess	regulation of cartilage development	HOXD11 HOXA11	3.65e-03	81	23	2	GO:0061035
GeneOntologyCellularComponent	main axon	ADORA2A DLG1 CRHBP	1.24e-04	89	23	3	GO:0044304
GeneOntologyCellularComponent	asymmetric synapse	ADORA2A DLG1 EEF2K SEMA4C	1.68e-03	477	23	4	GO:0032279
GeneOntologyCellularComponent	endoplasmic reticulum membrane	CYP4V2 ANKLE2 DLG1 CYP7B1 GRAMD4 TAB1	2.24e-03	1293	23	6	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	CYP4V2 ANKLE2 DLG1 CYP7B1 GRAMD4 TAB1	2.30e-03	1299	23	6	GO:0098827
GeneOntologyCellularComponent	neuron to neuron synapse	ADORA2A DLG1 EEF2K SEMA4C	2.35e-03	523	23	4	GO:0098984
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CYP4V2 ANKLE2 DLG1 CYP7B1 GRAMD4 TAB1	2.56e-03	1327	23	6	GO:0042175
MousePheno	increased lumbar vertebrae number	HOXD11 HOXA11	8.34e-06	4	17	2	MP:0004650
MousePheno	abnormal sclera morphology	CYP4V2 ADORA2A	6.23e-05	10	17	2	MP:0002698
MousePheno	increased presacral vertebrae number	HOXD11 HOXA11	1.08e-04	13	17	2	MP:0000464
MousePheno	fused carpal bones	HOXD11 HOXA11	1.26e-04	14	17	2	MP:0008915
MousePheno	sacral vertebral transformation	HOXD11 HOXA11	1.65e-04	16	17	2	MP:0004617
Domain	DUF3528	HOXD11 HOXA11	3.97e-06	3	22	2	PF12045
Domain	DUF3528	HOXD11 HOXA11	3.97e-06	3	22	2	IPR021918
Domain	CYTOCHROME_P450	CYP4V2 CYP7B1	2.03e-03	57	22	2	PS00086
Domain	-	CYP4V2 CYP7B1	2.10e-03	58	22	2	1.10.630.10
Domain	p450	CYP4V2 CYP7B1	2.10e-03	58	22	2	PF00067
Domain	Cyt_P450	CYP4V2 CYP7B1	2.25e-03	60	22	2	IPR001128
Domain	Homeobox_metazoa	HOXD11 HOXA11	4.98e-03	90	22	2	IPR020479
Domain	Ubiquitin-rel_dom	MYO7A TBCEL	1.96e-02	184	22	2	IPR029071
Domain	Homeobox_CS	HOXD11 HOXA11	2.00e-02	186	22	2	IPR017970
Pathway	REACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION	CYP4V2 MYO7A	3.95e-04	20	21	2	MM14888
Pathway	REACTOME_FORMATION_OF_THE_URETERIC_BUD	HOXD11 HOXA11	4.36e-04	21	21	2	M48244
Pathway	REACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION	CYP4V2 MYO7A	5.25e-04	23	21	2	M27174
Pathway	REACTOME_ENDOGENOUS_STEROLS	CYP4V2 CYP7B1	6.21e-04	25	21	2	M11184
Pathway	REACTOME_ENDOGENOUS_STEROLS	CYP4V2 CYP7B1	7.25e-04	27	21	2	MM14844
Pathway	REACTOME_TNFR1_INDUCED_NF_KAPPA_B_SIGNALING_PATHWAY	SPATA2 TAB1	1.09e-03	33	21	2	M27438
Pathway	REACTOME_TNFR1_INDUCED_NF_KAPPA_B_SIGNALING_PATHWAY	SPATA2 TAB1	1.09e-03	33	21	2	MM15180
Pubmed	Absence of mutations in the HOXA11 and HOXD11 genes in children with congenital renal malformations.	HOXD11 HOXA11	4.18e-07	2	23	2	19255789
Pubmed	Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11.	HOXD11 HOXA11	4.18e-07	2	23	2	7596412
Pubmed	Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development.	HOXD11 HOXA11	4.18e-07	2	23	2	16581055
Pubmed	Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning.	HOXD11 HOXA11	4.18e-07	2	23	2	8660870
Pubmed	Functional specificity of the Hoxa13 homeobox.	HOXD11 HOXA11	1.25e-06	3	23	2	11688568
Pubmed	Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum.	HOXD11 HOXA11	1.25e-06	3	23	2	9250683
Pubmed	Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney.	HOXD11 HOXA11	2.51e-06	4	23	2	12060755
Pubmed	A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis.	MYO7A DLG1	2.51e-06	4	23	2	15657400
Pubmed	Altered Hox expression and increased cell death distinguish Hypodactyly from Hoxa13 null mice.	HOXD11 HOXA11	4.18e-06	5	23	2	10470645
Pubmed	Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.	DLG1 SEMA4C	4.18e-06	5	23	2	11134026
Pubmed	Genetic analysis of a Hoxd-12 regulatory element reveals global versus local modes of controls in the HoxD complex.	HOXD11 HOXA11	4.18e-06	5	23	2	9521905
Pubmed	A Hox-Eya-Pax complex regulates early kidney developmental gene expression.	HOXD11 HOXA11	4.18e-06	5	23	2	17785448
Pubmed	Generation and expression of a Hoxa11eGFP targeted allele in mice.	HOXD11 HOXA11	4.18e-06	5	23	2	18942146
Pubmed	Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice.	HOXD11 HOXA11	4.18e-06	5	23	2	34010606
Pubmed	Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications.	HOXD11 HOXA11	4.18e-06	5	23	2	9391088
Pubmed	Duplication of the Hoxd11 gene causes alterations in the axial and appendicular skeleton of the mouse.	HOXD11 HOXA11	4.18e-06	5	23	2	12217321
Pubmed	Genetic analysis of a conserved sequence in the HoxD complex: regulatory redundancy or limitations of the transgenic approach?	HOXD11 HOXA11	6.26e-06	6	23	2	9733096
Pubmed	Choline kinase beta is required for normal endochondral bone formation.	HOXD11 HOXA11	8.77e-06	7	23	2	24637075
Pubmed	Non-homeodomain regions of Hox proteins mediate activation versus repression of Six2 via a single enhancer site in vivo.	HOXD11 HOXA11	8.77e-06	7	23	2	19716816
Pubmed	Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations.	HOXD11 HOXA11	8.77e-06	7	23	2	34408147
Pubmed	Genetic interaction of Gli3 and Alx4 during limb development.	HOXD11 HOXA11	8.77e-06	7	23	2	15968591
Pubmed	Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements.	HOXD11 HOXA11	1.17e-05	8	23	2	20978074
Pubmed	Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton.	HOXD11 HOXA11	1.17e-05	8	23	2	12869760
Pubmed	Hox11 paralogous genes are essential for metanephric kidney induction.	HOXD11 HOXA11	1.17e-05	8	23	2	12050119
Pubmed	Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model.	HOXD11 HOXA11	1.17e-05	8	23	2	26238020
Pubmed	AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins.	HOXD11 HOXA11	1.17e-05	8	23	2	9343407
Pubmed	Bone morphology is regulated modularly by global and regional genetic programs.	HOXD11 HOXA11	1.50e-05	9	23	2	31221640
Pubmed	Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod.	HOXD11 HOXA11	1.50e-05	9	23	2	14668414
Pubmed	"Self-regulation," a new facet of Hox genes' function.	HOXD11 HOXA11	1.50e-05	9	23	2	23913823
Pubmed	Targeted disruption of Hotair leads to homeotic transformation and gene derepression.	HOXD11 HOXA11	1.88e-05	10	23	2	24075995
Pubmed	Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts.	HOXD11 HOXA11	2.29e-05	11	23	2	23760953
Pubmed	VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.	HOXD11 HOXA11	2.75e-05	12	23	2	18519639
Pubmed	Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice.	HOXD11 HOXA11	2.75e-05	12	23	2	22916278
Pubmed	LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes.	HOXD11 HOXA11	2.75e-05	12	23	2	26633036
Pubmed	Breaking constraint of mammalian axial formulae.	HOXD11 HOXA11	3.25e-05	13	23	2	35017475
Pubmed	Hox11 genes are required for regional patterning and integration of muscle, tendon and bone.	HOXD11 HOXA11	3.79e-05	14	23	2	24154528
Pubmed	Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity.	HOXD11 HOXA11	3.79e-05	14	23	2	9834182
Pubmed	Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo.	HOXD11 HOXA11	3.79e-05	14	23	2	18485340
Pubmed	Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney.	HOXD11 HOXA11	3.79e-05	14	23	2	11493536
Pubmed	The mouse Ulnaless mutation deregulates posterior HoxD gene expression and alters appendicular patterning.	HOXD11 HOXA11	3.79e-05	14	23	2	9342041
Pubmed	Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.	HOXD11 HOXA11	4.37e-05	15	23	2	19938081
Pubmed	The apical ectodermal ridge is a timer for generating distal limb progenitors.	HOXD11 HOXA11	4.37e-05	15	23	2	18359901
Pubmed	Hoxd and Gli3 interactions modulate digit number in the amniote limb.	HOXD11 HOXA11	4.37e-05	15	23	2	17714700
Pubmed	Loss of the Tg737 protein results in skeletal patterning defects.	HOXD11 HOXA11	4.99e-05	16	23	2	12701101
Pubmed	Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13.	HOXD11 HOXA11	4.99e-05	16	23	2	27974206
Pubmed	A Hox Code Defines Spinocerebellar Neuron Subtype Regionalization.	HOXD11 HOXA11	4.99e-05	16	23	2	31747609
Pubmed	Ezh2 regulates anteroposterior axis specification and proximodistal axis elongation in the developing limb.	HOXD11 HOXA11	4.99e-05	16	23	2	21795281
Pubmed	Hox patterning of the vertebrate rib cage.	HOXD11 HOXA11	5.66e-05	17	23	2	17626057
Pubmed	Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.	HOXD11 HOXA11	5.66e-05	17	23	2	19168674
Pubmed	Multiple enhancers regulate Hoxd genes and the Hotdog LncRNA during cecum budding.	HOXD11 HOXA11	5.66e-05	17	23	2	24075990
Pubmed	Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development.	HOXD11 HOXA11	6.36e-05	18	23	2	16015334
Pubmed	Misexpression of Pknox2 in mouse limb bud mesenchyme perturbs zeugopod development and deltoid crest formation.	HOXD11 HOXA11	6.36e-05	18	23	2	23717575
Pubmed	Transcriptome analysis of the murine forelimb and hindlimb autopod.	HOXD11 HOXA11	7.10e-05	19	23	2	16059910
Pubmed	Plzf regulates limb and axial skeletal patterning.	HOXD11 HOXA11	7.10e-05	19	23	2	10835630
Pubmed	Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma.	HOXD11 HOXA11	7.10e-05	19	23	2	21858105
Pubmed	Shox2 regulates progression through chondrogenesis in the mouse proximal limb.	HOXD11 HOXA11	7.10e-05	19	23	2	23038774
Pubmed	Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs.	HOXD11 HOXA11	9.59e-05	22	23	2	26283362
Pubmed	Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression.	HOXD11 HOXA11	1.05e-04	23	23	2	16672333
Pubmed	The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13.	HOXD11 HOXA11	1.14e-04	24	23	2	31896583
Pubmed	The human HOX gene family.	HOXD11 HOXA11	1.68e-04	29	23	2	2574852
Pubmed	SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.	SPATA2 TAB1	1.92e-04	31	23	2	27307491
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	MYO7A DLG1 LARGE1	1.92e-04	171	23	3	20201926
Pubmed	Ndrg2 regulates vertebral specification in differentiating somites.	HOXD11 HOXA11	2.05e-04	32	23	2	22819676
Pubmed	Distinct roles and regulations for HoxD genes in metanephric kidney development.	HOXD11 HOXA11	2.18e-04	33	23	2	18159948
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	HOXA11 JMJD6 SUPT6H	2.35e-04	183	23	3	36129980
Pubmed	Atlas of Hox gene expression in the developing kidney.	HOXD11 HOXA11	2.90e-04	38	23	2	15042701
Pubmed	Complete mutation analysis panel of the 39 human HOX genes.	HOXD11 HOXA11	2.90e-04	38	23	2	11857506
Pubmed	Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.	HOXD11 HOXA11	3.05e-04	39	23	2	33257809
Pubmed	Quantification of Hox and surfactant protein-B transcription during murine lung development.	HOXD11 HOXA11	3.21e-04	40	23	2	19204410
Pubmed	Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development.	HOXD11 HOXA11	3.38e-04	41	23	2	30377232
Pubmed	Reduction of Hox gene expression by histone H1 depletion.	HOXD11 HOXA11	3.72e-04	43	23	2	22701719
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ANKLE2 DENND2A SUPT6H GRAMD4	3.72e-04	529	23	4	14621295
Pubmed	Nomenclature for human homeobox genes.	HOXD11 HOXA11	3.89e-04	44	23	2	1973146
Pubmed	Vertebrate homeobox gene nomenclature.	HOXD11 HOXA11	4.44e-04	47	23	2	1358459
Pubmed	New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.	HOXD11 HOXA11	5.03e-04	50	23	2	28188179
Pubmed	High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population.	HOXD11 HOXA11	6.30e-04	56	23	2	19591821
Pubmed	Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.	MYO7A DLG1	6.30e-04	56	23	2	22745667
GeneFamily	HOXL subclass homeoboxes	HOXD11 HOXA11	1.07e-03	52	17	2	518
CoexpressionAtlas	NK cells, NK.Sp, NK1.1+, Spleen, avg-3	ADORA2A GRAMD4 EEF2K CPNE7 SEMA4C	4.08e-05	409	21	5	GSM538315_500
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ADORA2A EEF2K SEMA4C	3.91e-05	129	23	3	5e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ADORA2A MYO7A CYP7B1	7.70e-05	162	23	3	64353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ADORA2A MYO7A CYP7B1	7.84e-05	163	23	3	9f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA2A CPNE7 SEMA4C	7.98e-05	164	23	3	7a51365bad2910c130bd952805f7a1bef51be481
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO7A DENND2A DLG1	8.13e-05	165	23	3	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA2A EEF2K CPNE7	8.13e-05	165	23	3	8741df8066a44c841752a99ad306d26ea68f5344
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRBV5-6 ADORA2A EEF2K	8.42e-05	167	23	3	e242827999caad08b0894d88ab97bc1df41b7650
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	COQ10A MRPL49 EEF2K	8.57e-05	168	23	3	ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell	356C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CYP4V2 TAB1 TBCEL	8.72e-05	169	23	3	fec669968a77060bd77ee8695034e35a642c984f
ToppCell	356C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CYP4V2 TAB1 TBCEL	8.72e-05	169	23	3	0425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	DENND2A DLG1 CPNE7	9.19e-05	172	23	3	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A DLG1 CPNE7	9.84e-05	176	23	3	b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A EEF2K CRHBP	9.84e-05	176	23	3	29cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A EEF2K CRHBP	9.84e-05	176	23	3	01774a86d7d92f31a056b753f9844f923038003e
ToppCell	facs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A DLG1 CPNE7	9.84e-05	176	23	3	057d2759fdc67176c25802b57a78064d8cc93205
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4V2 ADORA2A CPNE7	1.05e-04	180	23	3	5fdd10ffdf49f0e818f865ca095a3882b35c640e
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO7A DLG1 CPNE7	1.09e-04	182	23	3	0cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO7A DLG1 CPNE7	1.09e-04	182	23	3	2cc434e46985c66fc36de05344a67aa96d90abc9
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO7A DLG1 CPNE7	1.09e-04	182	23	3	3e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCell	5'-GW_trimst-1.5-LargeIntestine\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXD11 HOXA11 JMJD6	1.37e-04	197	23	3	0b2ad6a933ff1a325649cc8f139380fd158a1d42
Drug	Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; PC3; HT_HG-U133A	JMJD6 CYP7B1 TAB1 SEMA4C LARGE1	1.05e-06	196	22	5	5102_DN
Drug	resveratrol; Down 200; 50uM; MCF7; HG-U133A	JMJD6 DLG1 SUPT6H SEMA4C	3.06e-05	190	22	4	622_DN
Drug	Meticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A	JMJD6 CYP7B1 SUPT6H TAB1	3.18e-05	192	22	4	1792_UP
Drug	5155877; Up 200; 10uM; PC3; HT_HG-U133A	JMJD6 TBCEL SEMA4C LARGE1	3.18e-05	192	22	4	6544_UP
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A	DLG1 CYP7B1 SUPT6H SEMA4C	3.25e-05	193	22	4	4338_DN
Drug	Vitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A	HOXD11 ADORA2A TBCEL CPNE7	3.25e-05	193	22	4	3880_UP
Drug	Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; HL60; HT_HG-U133A	HOXD11 MYO7A TBCEL SEMA4C	3.31e-05	194	22	4	3100_UP
Drug	Roxarsone [121-19-7]; Down 200; 15.2uM; PC3; HT_HG-U133A	SPATA2 HOXA11 JMJD6 SEMA4C	3.31e-05	194	22	4	5051_DN
Drug	Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; PC3; HT_HG-U133A	HOXA11 TAB1 SEMA4C LARGE1	3.38e-05	195	22	4	4019_DN
Drug	Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A	HOXD11 HOXA11 ADORA2A MYO7A	3.45e-05	196	22	4	2876_UP
Drug	Mifepristone [84371-65-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	SPATA2 DLG1 CYP7B1 SUPT6H	3.45e-05	196	22	4	5827_DN
Drug	Condelphine [7633-69-4]; Down 200; 8.8uM; PC3; HT_HG-U133A	HOXA11 DENND2A SUPT6H TAB1	3.45e-05	196	22	4	6357_DN
Drug	Norethindrone [68-22-4]; Down 200; 13.4uM; PC3; HT_HG-U133A	SUPT6H GRAMD4 TAB1 CPNE7	3.52e-05	197	22	4	5055_DN
Drug	Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; PC3; HT_HG-U133A	HOXA11 CYP7B1 TAB1 CPNE7	3.59e-05	198	22	4	2099_UP
Drug	Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; PC3; HT_HG-U133A	DENND2A TAB1 CPNE7 SEMA4C	3.66e-05	199	22	4	4555_DN
Drug	Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A	SUPT6H GRAMD4 CPNE7 SEMA4C	3.66e-05	199	22	4	4534_DN
Drug	Tranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT_HG-U133A	HOXD11 DENND2A TAB1 TBCEL	3.73e-05	200	22	4	5762_UP
Drug	Nile blue	HOXD11 HOXA11	5.85e-05	12	22	2	CID000016938
Drug	AC1L40MO	ADORA2A JMJD6 EEF2K	2.77e-04	133	22	3	CID000099067
Drug	MG-262; Up 200; 0.1uM; PC3; HT_HG-U133A	ANKLE2 JMJD6 SUPT6H	4.84e-04	161	22	3	7068_UP
Drug	resveratrol; Down 200; 10uM; MCF7; HT_HG-U133A_EA	JMJD6 DLG1 SEMA4C	6.38e-04	177	22	3	841_DN
Drug	H-7 dihydrochloride; Down 200; 100uM; MCF7; HT_HG-U133A	SPATA2 JMJD6 SEMA4C	6.81e-04	181	22	3	5963_DN
Drug	Salbutamol [18559-94-9]; Up 200; 16.8uM; PC3; HT_HG-U133A	MYO7A DENND2A CYP7B1	6.92e-04	182	22	3	7376_UP
Drug	Isoconazole [27523-40-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A	HOXA11 ADORA2A DLG1	7.48e-04	187	22	3	7211_UP
Drug	Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A	HOXA11 GRAMD4 TAB1	7.60e-04	188	22	3	3770_DN
Drug	Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A	SPATA2 JMJD6 SEMA4C	7.60e-04	188	22	3	3291_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ANKLE2 JMJD6 DLG1	7.72e-04	189	22	3	1045_DN
Drug	Denatonium benzoate [3734-33-6]; Down 200; 9uM; HL60; HT_HG-U133A	SPATA2 SUPT6H TAB1	7.96e-04	191	22	3	3123_DN
Drug	AG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A	HOXD11 DLG1 CPNE7	8.20e-04	193	22	3	5909_DN
Drug	PHA-00851261E [724719-49-7]; Down 200; 10uM; PC3; HT_HG-U133A	TBCEL CPNE7 SEMA4C	8.20e-04	193	22	3	3773_DN
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A	HOXA11 ADORA2A CPNE7	8.20e-04	193	22	3	5904_UP
Drug	Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A	MYO7A JMJD6 CYP7B1	8.20e-04	193	22	3	5437_UP
Drug	Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	MYO7A SUPT6H CPNE7	8.32e-04	194	22	3	2828_UP
Drug	Niacin [59-67-6]; Up 200; 32.4uM; HL60; HT_HG-U133A	HOXA11 MYO7A TBCEL	8.32e-04	194	22	3	3043_UP
Drug	(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ADORA2A MYO7A TAB1	8.32e-04	194	22	3	3354_DN
Drug	Hexestrol [84-16-2]; Down 200; 14.8uM; PC3; HT_HG-U133A	JMJD6 CYP7B1 SEMA4C	8.32e-04	194	22	3	5776_DN
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A	DENND2A SUPT6H CPNE7	8.32e-04	194	22	3	4301_DN
Drug	Primidone [125-33-7]; Down 200; 18.4uM; PC3; HT_HG-U133A	HOXA11 SUPT6H TAB1	8.32e-04	194	22	3	6723_DN
Drug	Verteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A	ADORA2A MYO7A TBCEL	8.32e-04	194	22	3	3556_UP
Drug	Indomethacin [53-86-1]; Down 200; 11.2uM; PC3; HT_HG-U133A	DLG1 CYP7B1 CPNE7	8.32e-04	194	22	3	5049_DN
Drug	Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; PC3; HT_HG-U133A	CYP7B1 TAB1 CPNE7	8.45e-04	195	22	3	7394_UP
Drug	Amoxapine [14028-44-5]; Down 200; 12.8uM; PC3; HT_HG-U133A	DENND2A TAB1 TBCEL	8.45e-04	195	22	3	6650_DN
Drug	Prednisone [53-03-2]; Up 200; 11.2uM; PC3; HT_HG-U133A	DENND2A DLG1 LARGE1	8.45e-04	195	22	3	4577_UP
Drug	Pyrvinium pamoate [3546-41-6]; Down 200; 3.4uM; PC3; HT_HG-U133A	DENND2A SUPT6H GRAMD4	8.45e-04	195	22	3	6339_DN
Drug	PHA-00767505E [723337-45-9]; Up 200; 10uM; PC3; HT_HG-U133A	JMJD6 TBCEL SEMA4C	8.45e-04	195	22	3	6545_UP
Drug	Xylazine [7361-61-7]; Up 200; 18.2uM; HL60; HT_HG-U133A	MYO7A SUPT6H TBCEL	8.45e-04	195	22	3	2132_UP
Drug	Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A	SPATA2 JMJD6 CYP7B1	8.45e-04	195	22	3	6648_DN
Drug	Ramipril [87333-19-5]; Up 200; 9.6uM; PC3; HT_HG-U133A	CYP7B1 CPNE7 SEMA4C	8.45e-04	195	22	3	7144_UP
Drug	Homosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A	DENND2A SUPT6H CPNE7	8.45e-04	195	22	3	4533_DN
Drug	Stachydrine hydrochloride; Down 200; 22.2uM; PC3; HT_HG-U133A	DENND2A SUPT6H GRAMD4	8.58e-04	196	22	3	4469_DN
Drug	Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; PC3; HT_HG-U133A	JMJD6 DENND2A SEMA4C	8.58e-04	196	22	3	4494_DN
Drug	Rapamycin; Down 200; 0.1uM; PC3; HT_HG-U133A	JMJD6 DENND2A TBCEL	8.58e-04	196	22	3	4445_DN
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; PC3; HT_HG-U133A	DENND2A CPNE7 SEMA4C	8.58e-04	196	22	3	4549_DN
Drug	Debrisoquin sulfate [581-88-4]; Down 200; 9uM; HL60; HG-U133A	ANKLE2 DLG1 SUPT6H	8.58e-04	196	22	3	1591_DN
Drug	Kaempferol [520-18-3]; Up 200; 14uM; MCF7; HT_HG-U133A	ADORA2A JMJD6 CYP7B1	8.58e-04	196	22	3	3579_UP
Drug	Ethacrynic acid [58-54-8]; Up 200; 13.2uM; PC3; HT_HG-U133A	HOXD11 JMJD6 TBCEL	8.58e-04	196	22	3	5742_UP
Drug	Procyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	CYP7B1 TAB1 CPNE7	8.58e-04	196	22	3	2991_DN
Drug	Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	SUPT6H TBCEL SEMA4C	8.58e-04	196	22	3	3256_UP
Drug	Flutamide [13311-84-7]; Down 200; 14.4uM; PC3; HT_HG-U133A	HOXA11 DENND2A SUPT6H	8.58e-04	196	22	3	4539_DN
Drug	Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A	ADORA2A TAB1 TBCEL	8.58e-04	196	22	3	5280_DN
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A	CYP7B1 TBCEL SEMA4C	8.58e-04	196	22	3	3762_DN
Drug	Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; PC3; HT_HG-U133A	GRAMD4 TAB1 LARGE1	8.58e-04	196	22	3	2102_UP
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	HOXA11 TAB1 CPNE7	8.58e-04	196	22	3	6203_DN
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A	TAB1 CPNE7 SEMA4C	8.58e-04	196	22	3	3637_DN
Drug	Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; HL60; HT_HG-U133A	HOXD11 CYP7B1 LARGE1	8.58e-04	196	22	3	2381_UP
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A	HOXA11 CPNE7 LARGE1	8.58e-04	196	22	3	3740_DN
Drug	F0447-0125; Up 200; 10uM; PC3; HT_HG-U133A	HOXD11 DLG1 TBCEL	8.58e-04	196	22	3	6401_UP
Drug	PHA-00745360 [351320-33-7]; Up 200; 1uM; MCF7; HT_HG-U133A	HOXD11 ADORA2A CPNE7	8.70e-04	197	22	3	3910_UP
Drug	Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A	HOXA11 CPNE7 SEMA4C	8.70e-04	197	22	3	3832_UP
Drug	Oxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A	HOXA11 MYO7A LARGE1	8.70e-04	197	22	3	2103_UP
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; HL60; HT_HG-U133A	TAB1 CPNE7 LARGE1	8.70e-04	197	22	3	2903_DN
Drug	alpha-Santonin [481-06-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A	HOXD11 HOXA11 TBCEL	8.70e-04	197	22	3	3877_UP
Drug	Hexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; PC3; HT_HG-U133A	JMJD6 DENND2A LARGE1	8.70e-04	197	22	3	6620_DN
Drug	Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A	CYP7B1 TAB1 SEMA4C	8.70e-04	197	22	3	4091_DN
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A	DENND2A CPNE7 SEMA4C	8.70e-04	197	22	3	4544_DN
Drug	Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; PC3; HT_HG-U133A	HOXA11 SUPT6H GRAMD4	8.70e-04	197	22	3	7273_DN
Drug	N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; HL60; HT_HG-U133A	HOXD11 TBCEL LARGE1	8.70e-04	197	22	3	3085_UP
Drug	Tiabendazole [148-79-8]; Down 200; 19.8uM; HL60; HT_HG-U133A	JMJD6 TAB1 SEMA4C	8.70e-04	197	22	3	2479_DN
Drug	Vigabatrin [60643-86-9]; Down 200; 31uM; MCF7; HT_HG-U133A	JMJD6 SUPT6H TAB1	8.70e-04	197	22	3	5415_DN
Drug	Isoxicam [34552-84-6]; Down 200; 12uM; MCF7; HT_HG-U133A	SUPT6H GRAMD4 SEMA4C	8.70e-04	197	22	3	1698_DN
Drug	Altretamine [654-05-6]; Down 200; 19uM; HL60; HT_HG-U133A	JMJD6 TAB1 CPNE7	8.70e-04	197	22	3	3090_DN
Drug	Epitiostanol [2363-58-8]; Up 200; 13uM; HL60; HT_HG-U133A	SPATA2 HOXD11 TAB1	8.70e-04	197	22	3	2922_UP
Drug	Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; PC3; HT_HG-U133A	HOXA11 MYO7A CPNE7	8.70e-04	197	22	3	5759_UP
Drug	Propidium iodide [25535-16-4]; Down 200; 6uM; PC3; HT_HG-U133A	DENND2A TBCEL SEMA4C	8.70e-04	197	22	3	5803_DN
Drug	resveratrol; Down 200; 50uM; PC3; HG-U133A	ANKLE2 JMJD6 GRAMD4	8.70e-04	197	22	3	662_DN
Drug	Sulmazole [73384-60-8]; Down 200; 14uM; MCF7; HT_HG-U133A	ADORA2A TAB1 TBCEL	8.70e-04	197	22	3	4127_DN
Drug	Napelline [5008-52-6]; Up 200; 11.2uM; HL60; HT_HG-U133A	MYO7A DENND2A CYP7B1	8.70e-04	197	22	3	2522_UP
Drug	Gramine [87-52-5]; Down 200; 23uM; PC3; HT_HG-U133A	CYP7B1 SEMA4C LARGE1	8.70e-04	197	22	3	3999_DN
Drug	Sulfamethizole [144-82-1]; Up 200; 14.8uM; PC3; HT_HG-U133A	GRAMD4 TBCEL CPNE7	8.70e-04	197	22	3	5798_UP
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A	ANKLE2 SUPT6H GRAMD4	8.70e-04	197	22	3	3415_DN
Drug	LY 294002; Up 200; 0.1uM; HL60; HT_HG-U133A	HOXA11 MYO7A SEMA4C	8.70e-04	197	22	3	2676_UP
Drug	Proadifen hydrochloride [62-68-0]; Down 200; 10.2uM; PC3; HT_HG-U133A	DLG1 SUPT6H SEMA4C	8.83e-04	198	22	3	5807_DN
Drug	Benzthiazide [91-33-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A	JMJD6 TAB1 TBCEL	8.83e-04	198	22	3	3329_UP
Drug	5-aminosalicylic acid; Down 200; 100uM; MCF7; HG-U133A	DLG1 SUPT6H GRAMD4	8.83e-04	198	22	3	124_DN
Drug	Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; HL60; HT_HG-U133A	HOXA11 TBCEL SEMA4C	8.83e-04	198	22	3	2929_UP
Drug	Butacaine [149-16-6]; Down 200; 13uM; MCF7; HT_HG-U133A	ANKLE2 DLG1 SEMA4C	8.83e-04	198	22	3	6225_DN
Drug	Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A	HOXA11 TBCEL CPNE7	8.83e-04	198	22	3	3931_UP
Drug	Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; MCF7; HT_HG-U133A	ADORA2A JMJD6 CPNE7	8.83e-04	198	22	3	2294_UP
Drug	Lithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A	DENND2A CPNE7 SEMA4C	8.83e-04	198	22	3	4551_DN
Drug	Verapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; PC3; HT_HG-U133A	HOXA11 SUPT6H GRAMD4	8.83e-04	198	22	3	6287_DN
Disease	visfatin measurement	GRAMD4 TAB1	6.52e-05	17	21	2	EFO_0801230
Disease	Limb Deformities, Congenital	HOXD11 HOXA11	6.52e-05	17	21	2	C0206762
Disease	melanoma	MRPL49 MYO7A JMJD6	6.97e-04	248	21	3	C0025202
Disease	adverse effect, response to xenobiotic stimulus	CYP7B1 LARGE1	8.05e-04	59	21	2	EFO_0009658, GO_0009410
Disease	Amphetamine Abuse	ADORA2A LARGE1	1.30e-03	75	21	2	C0236807
Disease	Amphetamine Addiction	ADORA2A LARGE1	1.30e-03	75	21	2	C0236804
Disease	Amphetamine-Related Disorders	ADORA2A LARGE1	1.30e-03	75	21	2	C0236733
Disease	Kidney Diseases	HOXD11 HOXA11	1.78e-03	88	21	2	C0022658
Disease	acne	MRPL49 DLG1	3.55e-03	125	21	2	EFO_0003894
Disease	ovarian neoplasm	HOXD11 JMJD6	4.06e-03	134	21	2	C0919267
Disease	Malignant neoplasm of ovary	HOXD11 JMJD6	4.24e-03	137	21	2	C1140680

Protein segments in the cluster

Peptide	Gene	Start	Entry
YEDVPARNERIYVYE	ANKLE2	206	Q86XL3
SVVNPFIYAYRIREF	ADORA2A	281	P29274
IVAQYRPEEYSRFEA	DLG1	541	Q12959
YERFGEYVEDFRFQP	GRAMD4	171	Q6IC98
VEEFVERYERPYKPV	JMJD6	56	Q6NYC1
DFEPYVVVRRDCPEY	LARGE1	656	O95461
YQIRELEREFFFSVY	HOXA11	251	P31270
VNRVTFEYRQLEPYE	CRHBP	291	P24387
LIEYQERQLFEYFVV	DENND2A	556	Q9ULE3
VFTVDYYFEEVQRLR	CPNE7	76	Q9UBL6
YEVVSNVQEYREFVP	COQ10A	101	Q96MF6
YQIRELEREFFFNVY	HOXD11	276	P31277
REFFQQIIEYTEEYR	CYP4V2	71	Q6ZWL3
IFEAPEEFRYDRFIE	CYP7B1	406	O75881
RYIEPVDRDVYFEDV	EEF2K	171	O00418
GRVEPYVDFAEFYRL	TAB1	476	Q15750
EYQLEEIQRVFEGPY	SEMA4C	331	Q9C0C4
PRFVESVDEYQFVER	MRPL49	36	Q13405
FEVPFIAFYRKEYVE	SUPT6H	371	Q7KZ85
DPFYRFRLIQFYEVV	SPATA2	56	Q9UM82
GPQFIFQYYEEEERQ	TRBV5-6	61	A0A599
FQYYEEEERQRGNFP	TRBV5-6	66	A0A599
ERFFIRYYVDVPQEE	TBCEL	301	Q5QJ74
RYYVDVPQEEVPFRY	TBCEL	306	Q5QJ74
YSFVEFVERYRVLLP	MYO7A	676	Q13402