Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsucrose transmembrane transporter activity

SLC45A4 SLC45A3

1.89e-0441132GO:0008515
GeneOntologyMolecularFunctionsucrose:proton symporter activity

SLC45A4 SLC45A3

1.89e-0441132GO:0008506
GeneOntologyMolecularFunctionoligosaccharide transmembrane transporter activity

SLC45A4 SLC45A3

1.89e-0441132GO:0015157
GeneOntologyMolecularFunctiondisaccharide transmembrane transporter activity

SLC45A4 SLC45A3

1.89e-0441132GO:0015154
GeneOntologyMolecularFunctionsucrose:monoatomic cation symporter activity

SLC45A4 SLC45A3

1.89e-0441132GO:0009669
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

TCIRG1 ATP13A2 SLC45A4 SLC6A8 SLC12A9 SLC45A3 ATP12A UQCRFS1P1

3.16e-043011138GO:0022853
GeneOntologyMolecularFunctiontransporter activity

LRRC8E ESYT1 PIEZO1 PEX6 TCIRG1 ATP13A2 AQP9 RYR1 SLC45A4 SLC6A8 CNNM3 SLC12A9 SLC45A3 PKD1 ATP12A SLC14A2 SLC33A1 UQCRFS1P1

3.24e-04128911318GO:0005215
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

PLEKHG2 DENND11 DENND3 ARHGEF10L ARHGEF39 HERC1 GDPGP1

3.46e-042311137GO:0005085
GeneOntologyMolecularFunctioncarbohydrate:proton symporter activity

SLC45A4 SLC45A3

8.69e-0481132GO:0005351
GeneOntologyMolecularFunctiontransmembrane transporter activity

LRRC8E PIEZO1 TCIRG1 ATP13A2 AQP9 RYR1 SLC45A4 SLC6A8 CNNM3 SLC12A9 SLC45A3 PKD1 ATP12A SLC14A2 SLC33A1 UQCRFS1P1

9.83e-04118011316GO:0022857
GeneOntologyMolecularFunctionurea transmembrane transporter activity

AQP9 SLC14A2

1.11e-0391132GO:0015204
DomainLRR_8

LRRC8E LRRC39 VASN ISLR LRRC43 PKD1 SCRIB

7.28e-051711117PF13855
DomainCHD_N

CHD3 CHD5

1.05e-0431112IPR012958
DomainCHD_C2

CHD3 CHD5

1.05e-0431112IPR012957
DomainCHDCT2

CHD3 CHD5

1.05e-0431112PF08074
DomainCHDNT

CHD3 CHD5

1.05e-0431112PF08073
DomainDUF1086

CHD3 CHD5

1.05e-0431112IPR009462
DomainDUF1087

CHD3 CHD5

1.05e-0431112IPR009463
DomainDUF1087

CHD3 CHD5

1.05e-0431112PF06465
DomainDUF1086

CHD3 CHD5

1.05e-0431112PF06461
DomainDUF1087

CHD3 CHD5

1.05e-0431112SM01147
DomainDUF1086

CHD3 CHD5

1.05e-0431112SM01146
DomainLRR

LRRC8E LRRC39 VASN ISLR LRRC43 PKD1 SCRIB

1.99e-042011117PS51450
DomainLRR_TYP

LRRC8E LRRC39 VASN ISLR PKD1 SCRIB

6.62e-041771116SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC8E LRRC39 VASN ISLR PKD1 SCRIB

6.62e-041771116IPR003591
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LRRC8E MAN2A2 ESYT1 PIEZO1 INTS1 HECTD4 PEX6 KTI12 DDX56 GTF2IRD1 ATP13A2 RYR1 ARHGEF10L SLC6A8 GAREM2 SLC45A3 MTOR NBEAL2 CHD5 PKD1 MAP3K11 PDZD8 MICAL3 HERC1 PRRT4

2.80e-1411051162535748872
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

COL7A1 B4GALNT1 MAN2A2 CALR VASN ESYT1 PIEZO1 MARCHF6 HLA-E ITGA6 ERLEC1 SLC6A8 CNNM3 PDF COCH IPO13 SCRIB SLC33A1 MSLN

1.78e-0812011161935696571
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ANGEL1 PEX6 DIDO1 GOLT1B CHD3 DENND3 AP5B1 MICAL3 SCRIB SLC33A1 RPL6 HEATR3

1.93e-066501161238777146
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

LRRC8E CALR DNAJC25 ESYT1 HLA-E ANGEL1 ITGA6 ERLEC1 SLC6A8 CNNM3 PDZD8 RHBDD3 SLC33A1 RPL6

3.67e-069521161438569033
Pubmed

Defining the membrane proteome of NK cells.

CALR ESYT1 MARCHF6 INTS1 DDX56 GOLT1B RBM23 CNNM3 MTOR NBEAL2 CHD5 MAP3K11 PDZD8 SLC33A1 RPL6

8.25e-0611681161519946888
Pubmed

Regulation of mTOR by polycystin-1: is polycystic kidney disease a case of futile repair?

MTOR PKD1

1.10e-052116217102641
Pubmed

Functional and molecular expression of AQP9 channel and UT-A transporter in normal and preeclamptic human placentas.

AQP9 SLC14A2

1.10e-052116216480766
Pubmed

Impaired lymphoid extracellular matrix impedes antibacterial immunity in epidermolysis bullosa.

COL7A1 COCH

1.10e-052116229305555
Pubmed

Ryanodine receptor-ankyrin interaction regulates internal Ca2+ release in mouse T-lymphoma cells.

ANK1 RYR1

1.10e-05211627629097
Pubmed

Anorexigenic and orexigenic hormone modulation of mammalian target of rapamycin complex 1 activity and the regulation of hypothalamic agouti-related protein mRNA expression.

MTOR AGRP

1.10e-052116222456226
Pubmed

Activity-independent targeting of mTOR to lysosomes in primary osteoclasts.

TCIRG1 MTOR

1.10e-052116228592812
Pubmed

Polycystin-1 affects cancer cell behaviour and interacts with mTOR and Jak signalling pathways in cancer cell lines.

MTOR PKD1

3.30e-053116231251475
Pubmed

A polypeptide binding conformation of calreticulin is induced by heat shock, calcium depletion, or by deletion of the C-terminal acidic region.

CALR HLA-E

3.30e-053116215383281
Pubmed

mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex.

MTOR PKD1

3.30e-053116226931735
Pubmed

Elucidating the mechanism of IL-1β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway.

PIEZO1 MTOR

3.30e-053116238134572
Pubmed

Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.

PIEZO1 MTOR

3.30e-053116236112948
Pubmed

Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae.

SLC45A4 SLC45A3

3.30e-053116225164149
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ANK1 INTS1 ERLEC1 DNAH14 RYR1 NOXO1 PKD1 SCRIB HEATR3 PLXNB3 PCMT1

3.72e-057361161129676528
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

HLA-E INTS1 PEX6 ITGA6 TCIRG1 DENND11 CNNM3 GOLGA7 IPO13 RHBDD3 HERC1 ATP12A SLC33A1

5.57e-0510611161333845483
Pubmed

Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase.

BID HERC1

6.59e-054116225408501
Pubmed

TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide.

CALR HLA-E

6.59e-05411629427624
Pubmed

Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.

MTOR PKD1

6.59e-054116219255143
Pubmed

Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons.

MTOR AGRP

6.59e-054116222884327
Pubmed

The role of c-Src in integrin (α6β4) dependent translational control.

ITGA6 MTOR

6.59e-054116224180592
Pubmed

Integral and associated lysosomal membrane proteins.

VASN TCIRG1 ATP13A2 MTOR AP5B1

6.70e-05126116517897319
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

CALR GART ANGEL1 GOLT1B SLC6A8 MTOR IPO13 RHBDD3 RPL6 HEATR3

7.32e-056571161036180527
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PIEZO1 MARCHF6 HECTD4 DIDO1 ARHGEF10L STAB1 NBEAL2 CHD5 IPO13

7.35e-05529116914621295
Pubmed

mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior.

MTOR AGRP

1.10e-045116226159924
Pubmed

Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.

COL7A1 FREM3

1.10e-045116217251066
Pubmed

Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.

RYR1 PKD1

1.10e-045116211818962
Pubmed

The genomic organization of a human creatine transporter (CRTR) gene located in Xq28.

SLC6A8 PLXNB3

1.10e-04511628661155
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

ASPHD1 CALR MARCHF6 HLA-E SLC45A4 SLC6A8 PKD1 IPO13 SCRIB PCMT1

1.19e-046971161028298427
Pubmed

Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease.

MTOR PKD1

1.64e-046116220852388
Pubmed

alpha3beta1 Integrin is required for normal development of the epidermal basement membrane.

COL7A1 ITGA6

2.29e-04711629151677
Pubmed

Neural basis for regulation of vasopressin secretion by anticipated disturbances in osmolality.

AVP AGRP

2.29e-047116234585668
Pubmed

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.

HLA-E HECTD4 SLC14A2

2.59e-0437116322797727
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

STXBP5 ESYT1 ANGEL1 PEX6 ITGA6 PDZD8 RHBDD3 SLC33A1

2.98e-04504116834432599
Pubmed

Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells.

ITGA6 MTOR

3.05e-048116212105188
Pubmed

An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger.

AVP AGRP

3.91e-049116224487620
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

CHD3 ERLEC1 CNNM3 MOV10L1 HERC1 PCMT1

4.01e-04285116632838362
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZHX3 STXBP5 DENND11 IGDCC4 MICAL3 SCRIB PLXNB3

4.46e-04407116712693553
Pubmed

ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly.

CALR HLA-E

4.88e-041011629545232
Pubmed

A model for obesity and gigantism due to disruption of the Ankrd26 gene.

MTOR AGRP

4.88e-0410116218162531
Pubmed

The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits.

AVP AGRP

4.88e-0410116230879785
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

SFTPB DNAH14 DNAH9

5.27e-044711638812413
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ESYT1 ITGA6 SLC6A8 CNNM3 FAM171A2 MICAL3 SCRIB

5.45e-04421116736976175
Pubmed

Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.

HECTD4 RPL6

5.95e-0411116221642993
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ITGA6 SLC6A8 CNNM3 FAM171A2 MTOR NBEAL2 MICAL3 SCRIB

6.62e-04569116830639242
Pubmed

BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.

CHD3 BID CHD5

8.36e-0455116333067418
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

CALR ESYT1 ITGA6 SLC6A8 CNNM3 FAM171A2 SLC33A1

9.99e-04467116730194290
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

CALR ESYT1 ITGA6 SLC6A8 CNNM3 PDZD8 SLC33A1

1.01e-03468116731056421
Pubmed

The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development.

ITGA6 ARHGEF10L SCRIB

1.03e-0359116326371508
Pubmed

DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.

CHD3 CHD5

1.13e-0315116235695185
Pubmed

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

COL7A1 STAB1 NBEAL2

1.18e-0362116319367581
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ESYT1 ERLEC1 CNNM3 FAM171A2 SLC12A9 MTOR RHBDD3 SCRIB SLC33A1 HEATR3

1.25e-039421161031073040
Pubmed

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

HECTD4 RPL6

1.28e-0316116221572416
Pubmed

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

CHD3 CHD5

1.45e-0317116227806305
Pubmed

Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.

CBLN3 STRCP1

1.45e-0317116220856818
Pubmed

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians.

ANK1 PIEZO1

1.45e-0317116224647736
Pubmed

Integrin-linked kinase is an adaptor with essential functions during mouse development.

ITGA6 MTOR

1.63e-0318116219829382
Pubmed

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.

CALR ERLEC1 MTOR HERC1

1.64e-03150116432423001
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

LRRC39 CBLN3 CD177 VASN INTS1 GOLT1B ISLR ERLEC1 COCH NBEAL2

1.73e-039851161012975309
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

INTS1 CHD5 MICAL3 USP35

1.76e-03153116410718198
Pubmed

Specification of select hypothalamic circuits and innate behaviors by the embryonic patterning gene dbx1.

AVP AGRP

1.82e-0319116225864637
Pubmed

Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.

HLA-E SLC45A3

2.01e-0320116221738478
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

COL7A1 ITGA6

2.22e-0321116227856617
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

ITGA6 ERLEC1 CNNM3 CHST7

2.27e-03164116432409323
Pubmed

Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.

PKD1 SCRIB

2.44e-0322116227582005
Pubmed

SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity.

ITGA6 SCRIB

2.67e-0323116233526661
Pubmed

Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.

ITGA6 MAP3K11

2.67e-0323116223152823
Pubmed

Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress.

CALR ESYT1 ERLEC1 SLC33A1

2.80e-03174116432149426
Pubmed

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.

CALR ERLEC1 BID IPO13 RPL6 PCMT1

2.84e-03418116635338135
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

STXBP5 MARCHF6 ANGEL1 CNNM3 SCRIB HERC1 SLC33A1 HEATR3

2.88e-03719116835337019
Pubmed

Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly.

PLEKHG2 ATG4D

2.90e-0324116233220177
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

VASN ESYT1 ITGA6 CCDC120 SCRIB RPL6 PCMT1

2.93e-03565116725468996
InteractionTOP3B interactions

LRRC8E MAN2A2 ESYT1 PIEZO1 INTS1 HECTD4 PEX6 KTI12 DDX56 GTF2IRD1 ATP13A2 RYR1 ARHGEF10L SLC6A8 GAREM2 SLC45A3 MTOR NBEAL2 CHD5 PKD1 MAP3K11 PDZD8 MICAL3 HERC1 PRRT4

4.55e-07147011325int:TOP3B
InteractionRAC1 interactions

VASN STXBP5 ESYT1 ITGA6 DDX56 GOLT1B PLEKHG2 SLC6A8 CNNM3 PDF FAM171A2 MTOR GOLGA7 MAP3K11 PDZD8 MICAL3 SCRIB SLC33A1 RPL6

6.76e-06106311319int:RAC1
InteractionKCNMB3 interactions

LRRC8E ESYT1 ATP13A2 PDZD8 ATP12A

1.17e-05531135int:KCNMB3
InteractionHCST interactions

LRRC8E INTS1 DENND11 MTOR AP5B1 IPO13 ATP12A HEATR3

2.05e-052051138int:HCST
InteractionGPR17 interactions

INTS1 SLC6A8 MIGA2 SLC12A9 MTOR IPO13 ATP12A SLC33A1 HEATR3

3.12e-052831139int:GPR17
Cytoband2p12-p11.2

SFTPB CNNM3

3.85e-05411722p12-p11.2
CoexpressionGSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_DN

ZHX3 ANK1 DND1 SLC12A9 AP5B1 RHBDD3 SEL1L2 ACCSL

3.35e-062001178M3047
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#1_top-relative-expression-ranked_1000

STXBP5 TCIRG1 KTI12 NBEAL2 MAP3K11 CHST7

2.08e-051041146DevelopingKidney_e15.5_Endothelial cells_emap-29977_k1_1000
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CBLN3 PLEKHG2 DND1 MPIG6B AQP9 PRRT4

1.55e-0613511767e3c840b40c41715ff7120a88b8b3f223df4f25a
ToppCellwk_15-18-Hematologic-Meg-ery-Definitive_erythroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CBLN3 ANK1 HECTD4 MIGA2 HERC1 ATG4D

8.70e-06182117693841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAN2A2 ANK1 HECTD4 SLC6A8 HERC1 ATG4D

8.70e-0618211760c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CD177 KTI12 IGDCC4 STAB1 USP35 GDPGP1

9.55e-0618511761b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CD177 KTI12 IGDCC4 STAB1 USP35 GDPGP1

9.55e-06185117602cbf492bc40abebaa93a3a208888afae72fbe06
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A2 ABI3BP ANGEL1 PLEKHG2 STAB1 FAM171A2

9.84e-06186117637860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A2 ABI3BP ANGEL1 PLEKHG2 STAB1 FAM171A2

9.84e-06186117660830822d3de3147816693404fd03392e04c2b8e
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A2 ABI3BP ANGEL1 PLEKHG2 STAB1 FAM171A2

9.84e-061861176baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCellIPF-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

SFTPB MMP23B FREM3 DENND3 NBEAL2 MSLN

9.84e-061861176d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MAN2A2 ANK1 HECTD4 SLC6A8 MIGA2 HERC1

1.21e-051931176be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

ABI3BP PIEZO1 MMP23B DENND3 NBEAL2 MSLN

1.33e-0519611766c99d29162848161c1f166a032320f87a5d5a631
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ABI3BP PIEZO1 MMP23B FREM3 DENND3 NBEAL2

1.36e-05197117669d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCellASK452-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

ASPHD1 SFTPB CALR HLA-E ITGA6 RPL6

1.36e-051971176e92757e988888347c74286cc42c262b03159b0b9
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ABI3BP PIEZO1 MMP23B FREM3 DENND3 NBEAL2

1.36e-051971176e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3BP DNAJC25 VASN MMP23B GOLT1B ISLR

1.40e-051981176b086af292a508a156266c2d899ba1caf820bf61c
ToppCelltumor_Lung-Fibroblasts-COL14A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

BNC2 ABI3BP VASN MMP23B ISLR IGDCC4

1.40e-05198117674f2c7ef702b25a5b99e56121229e678ed992524
ToppCell(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

ABI3BP PIEZO1 MMP23B FREM3 DENND3 NBEAL2

1.44e-0519911765a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNC2 ABI3BP VASN MMP23B ISLR RPL6

1.44e-0519911768d71e1fc92ee24deedf23fbb1a85a7fba0d8d436
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNC2 ABI3BP VASN MMP23B ISLR RPL6

1.44e-05199117649690494270981eec5b5261c59e0545dff90cc21
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TCIRG1 PLEKHG2 ASTL STAB1 AP5B1 RHBDD3

1.49e-05200117688d713dfc792e7609bf7ecfb28f87cb748088570
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ASPHD1 DNAJC25 PEX6 PLEKHG2 MPIG6B MIGA2

1.49e-0520011766b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ASPHD1 DNAJC25 PEX6 PLEKHG2 MPIG6B MIGA2

1.49e-052001176be83f442179ba4217d12f0458059586ff3130991
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NPR2 ANGEL1 FREM3 CHD5 C1QTNF12

4.78e-051501175ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAN2A2 ANK1 ISLR GTF2IRD1 DNAH14

5.09e-051521175ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Testicular_Germ_Cell_Tumor|TCGA-Testes / Sample_Type by Project: Shred V9

VASN MMP23B ARHGEF10L SYT8 C1QTNF12

5.76e-051561175f9eb18a0f00de211fab36d7d88fcf08276d53dcc
ToppCellChildren_(3_yrs)-Immune-mast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 CD177 STXBP5 SLC45A3 SMYD3

5.94e-051571175ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC43 RYR1 AGRP DNAH9 SLC14A2

6.30e-05159117500a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MAN2A2 ANK1 ISLR GTF2IRD1 DNAH14

6.49e-05160117519105debef96ea0c267d6a1d332303ec668ae47e
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 AQP9 ZC3H10 PKD1 IRGC

7.73e-05166117513027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 AQP9 ZC3H10 PKD1 IRGC

7.73e-051661175b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 ANK1 RYR1 SEL1L2 DNAH9

7.95e-0516711753edb0570e583bb527165bcd8a4c25a042054043b
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA6 ARHGEF10L NOXO1 ATP12A GP2

8.18e-0516811753e3f611e9bbec8224264666be14a4e7db343070e
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LRRC43 RYR1 ACCSL MSLN

8.56e-05881174b4620e79ea80681305434707e87cb02a7c6a5e4f
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LRRC43 RYR1 ACCSL MSLN

8.56e-058811747992f8e621edf464bffcb70a6cc5f3b60c1d96f8
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LRRC43 RYR1 ACCSL MSLN

8.56e-05881174b7b55f51af8ffa82813a4747580985a430da9ed1
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL7A1 GTF2IRD1 MPIG6B COCH RHBDD3

9.13e-051721175df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A2 CHD3 DND1 ARHGEF10L MSLN

9.39e-0517311756e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A2 CHD3 DND1 ARHGEF10L MSLN

9.39e-0517311754c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

COL7A1 VASN CHD3 ARHGEF39 MTOR

9.64e-051741175fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellwk_15-18-Epithelial-Proximal_epithelial-SMG_basal_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL7A1 ITGA6 SLC6A8 C1QTNF12 PLXNB3

1.02e-041761175045b12c90f7dd49a9778dadcdf8f18125b380531
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 ABI3BP CD177 SFTPB SYT8

1.05e-04177117575cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ZHX3 COL7A1 ITGA6 PLEKHG2 AQP9

1.05e-041771175eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL7A1 CD177 ARHGEF10L BID USP35

1.10e-041791175af03705a783e77f75c44fdfa793cfdccbf9dd91c
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASPHD1 DENND11 NOXO1 USP35 GP2

1.10e-041791175c7d7a66fca6a41de0af3cc2b75a29a54456842cd
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABI3BP ITGA6 SLC45A4 STAB1 PRRT4

1.13e-041801175baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 ABI3BP MMP23B IGDCC4 MICAL3

1.13e-04180117508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABI3BP ITGA6 SLC45A4 STAB1 PRRT4

1.13e-0418011752d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABI3BP ITGA6 SLC45A4 STAB1 PRRT4

1.13e-0418011750f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRRC8E ABI3BP STAB1 SYT8 PRRT4

1.22e-0418311756f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 ABI3BP CD177 SFTPB SYT8

1.22e-041831175ec2af3402b51f11466d2a5783a6b33746b6a7fc9
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ABI3BP PIEZO1 MMP23B DENND3 NBEAL2

1.25e-041841175c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ABI3BP PIEZO1 MMP23B DENND3 NBEAL2

1.25e-0418411751ed558a88215b248431c524ea16f13d9022ae98c
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK1 HECTD4 SLC6A8 MICAL3 HERC1

1.29e-041851175e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CD177 SFTPB INTS15 PKD1 HEATR3

1.32e-04186117574c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BNC2 ASPHD1 ABI3BP MMP23B MSLN

1.32e-0418611757812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABI3BP VASN MMP23B ISLR IGDCC4

1.32e-04186117507d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BNC2 MMP23B ISLR DND1 ARMC2

1.35e-041871175fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ABI3BP MMP23B FREM3 NBEAL2 MSLN

1.35e-041871175f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3BP STAB1 FAM171A2 SLC45A3 CCDC120

1.39e-041881175a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3BP STAB1 FAM171A2 SLC45A3 CCDC120

1.39e-04188117554550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNC2 ABI3BP MMP23B ISLR SYT8

1.42e-0418911751821ae4a6e37ee4c6308071883f3f447a7c53c53
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNC2 ABI3BP MMP23B ISLR SYT8

1.42e-0418911751e4d7e8dc98b3d70351e6a6c2aaf9ca01f141b8f
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 ABI3BP VASN ISLR IGDCC4

1.42e-041891175d531399749409d614adca13d181830c6e3287508
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK1 HECTD4 SLC6A8 MICAL3 HERC1

1.42e-0418911751900e574870fc647bfa11c732a72f3d38aab717c
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNC2 ABI3BP MMP23B ISLR SYT8

1.42e-0418911751dc415ed41815f4296dafd8cf7f3e014c44db1db
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABI3BP STAB1 FAM171A2 SLC45A3 CCDC120

1.46e-041901175e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABI3BP STAB1 FAM171A2 SLC45A3 CCDC120

1.46e-041901175f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABI3BP STAB1 FAM171A2 SLC45A3 CCDC120

1.46e-041901175b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 ABI3BP MMP23B ISLR IGDCC4

1.53e-041921175e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ATP13A2 DENND3 STAB1 PRRT4

1.60e-041941175f159ef8541d75a4e98468947f231bb463bec922c
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SFTPB MMP23B DENND3 NBEAL2 MSLN

1.64e-04195117568f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellAT1_cells|World / lung cells shred on cell class, cell subclass, sample id

ABI3BP MMP23B DENND3 NBEAL2 MSLN

1.64e-041951175792d6a49b0a875a00569071183d195287a9925c5
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SFTPB MMP23B DENND3 NBEAL2 MSLN

1.64e-0419511752a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HLA-E TCIRG1 PLEKHG2 AQP9 STAB1

1.64e-0419511750ec1b572bbb92b6da3440139366a4c1743b1ad92
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BNC2 ABI3BP VASN MMP23B ISLR

1.68e-041961175525d6c8a277364e624e7cc586275f8a891436b57
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SFTPB MMP23B DENND3 NBEAL2 MSLN

1.68e-041961175eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 ABI3BP MMP23B MOV10L1 SLC14A2

1.72e-0419711750dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellTracheal-NucSeq-Stromal-Mesofibroblastic-Mesothelia|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABI3BP ISLR DND1 GDPD4 IPO13

1.72e-041971175e91572edbe48d40269ee2cf7c858764cff6985ac
ToppCellTracheal-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABI3BP ISLR DND1 GDPD4 IPO13

1.72e-0419711757e3f78a61089d1200cc6b0fa2034bf2998651694
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 ABI3BP MMP23B ISLR IGDCC4

1.76e-041981175c66097ae9ba0b50561083c423565665958ef0bb8
ToppCellsevere-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARRDC4 PLEKHG2 AQP9 DENND3 STAB1

1.76e-041981175d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABI3BP VASN MMP23B ISLR IGDCC4

1.81e-0419911759672230aa0bc6a7289050c955f5154ca183a5159
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABI3BP VASN MMP23B ISLR IGDCC4

1.81e-041991175e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANK1 HECTD4 MPIG6B GAREM2 SLC45A3

1.81e-0419911756c174dbcc25b980f10a3d1dfe39e613acac73bb6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNC2 ABI3BP MMP23B IGDCC4 RPL6

1.81e-04199117508bdcabc3fce787578a8eb66fc8412b0974fa6cc
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANK1 HECTD4 MPIG6B GAREM2 SLC45A3

1.81e-041991175284ee9632413f6404fc0b0c7c393ad813db834f2
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

ANGEL1 DDX56 ARHGEF10L MTOR NBEAL2

1.81e-041991175fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

PIEZO1 ITGA6 TCIRG1 DENND3 RYR1

1.85e-0420011750eccf41edefc3b8b5d0316f57d5ba572949aec2b
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABI3BP VASN MMP23B ISLR IGDCC4

1.85e-04200117528e5354008adf97b17333f17f8cbef930db6729a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

PIEZO1 ITGA6 TCIRG1 DENND3 RYR1

1.85e-04200117501d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANK1 MPIG6B BID STAB1 NBEAL2

1.85e-042001175326cae37cacd94b423a6ac8873ea56c5abaf0a0b
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

BNC2 ABI3BP VASN MMP23B ISLR

1.85e-042001175954fee8425673e76198be414f5f6c4e3597c1919
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

BNC2 ABI3BP VASN MMP23B ISLR

1.85e-042001175bfa73bc5f8a6c7de8353ca049a921ef19f7f4437
ToppCellLung_Parenchyma-Severe-Mesenchymal|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BNC2 ABI3BP VASN MMP23B ISLR

1.85e-0420011756ce8e2cf689523993d909a27daec3d6a5824d13c
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BNC2 ABI3BP VASN MMP23B ISLR

1.85e-042001175907427e85cebe5a18c8a310e2ffa0e180ea3cb77
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABI3BP VASN MMP23B ISLR RPL6

1.85e-042001175a603e8a999612d523bbce9d0feca9296d4a24c97
ToppCell15-Airway-Mesenchymal|Airway / Age, Tissue, Lineage and Cell class

BNC2 VASN MMP23B ISLR RPL6

1.85e-04200117513c4835b98e1bb91c2d04e08cdeaed8eba30b1d9
ToppCellParenchyma_COVID-19-Stromal-TX|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

BNC2 ABI3BP VASN MMP23B ISLR

1.85e-0420011758472baa74c48b67c5f08223025885c833458290b
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABI3BP VASN MMP23B ISLR IGDCC4

1.85e-04200117556536236a7012efdb28f85b40e464f3da3e87ce8
Diseasecortical thickness

ZHX3 BNC2 NPR2 B4GALNT1 ARRDC4 ATP13A2 DENND3 SLC45A4 STAB1 COCH GOLGA7 PKD1 MICAL3 USP35

8.38e-05111311214EFO_0004840
Diseaseautosomal dominant polycystic kidney disease (is_implicated_in)

MTOR PKD1

8.53e-0541122DOID:898 (is_implicated_in)
Diseasetemporal lobe epilepsy (implicated_via_orthology)

AVP MTOR

5.05e-0491122DOID:3328 (implicated_via_orthology)
Diseasevascular dementia (biomarker_via_orthology)

AVP MTOR

1.26e-03141122DOID:8725 (biomarker_via_orthology)
DiseaseIschemic stroke, tissue plasminogen activator measurement

STXBP5 HECTD4

1.45e-03151122EFO_0004791, HP_0002140
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

MTOR PKD1

1.65e-03161122DOID:0110861 (implicated_via_orthology)
Diseasecortical surface area measurement

ZHX3 BNC2 NPR2 CBLN3 ARRDC4 TSPY26P ATP13A2 DENND3 SLC45A4 COCH PKD1 USP35 PCMT1

1.78e-03134511213EFO_0010736
Diseasereticulocyte count

BNC2 ANK1 PIEZO1 HECTD4 TCIRG1 ERLEC1 DENND3 SLC45A4 PKD1 HERC1 RPL6

2.11e-03104511211EFO_0007986
Diseaseportal hypertension (implicated_via_orthology)

AVP MTOR

2.34e-03191122DOID:10762 (implicated_via_orthology)
Diseasefactor VIII measurement, Ischemic stroke

STXBP5 HECTD4

2.34e-03191122EFO_0004630, HP_0002140
Diseaserenal system measurement, blood urea nitrogen measurement

HECTD4 SLC14A2

3.14e-03221122EFO_0004741, EFO_0004742
Diseasetonsillectomy risk measurement

HLA-E HECTD4 ITGA6 SLC45A4 RPL6

3.19e-032601125EFO_0007924

Protein segments in the cluster

PeptideGeneStartEntry
GIPLGLAGSIPLILQ

SLC33A1

86

O00400
RGLVLINPQNPLGDI

ACCSL

321

Q4AC99
IRRPDQALLPELPGL

AGRP

31

O00253
GAPRGLEPIAIGLLI

AQP9

186

O43315
LVPGGPVLLVLCGLL

ERLEC1

11

Q96DZ1
GVLRVILEPLIGDLP

ESYT1

241

Q9BSJ8
GTDQGVIVLLPVPRL

ARHGEF10L

1081

Q9HCE6
KPLPPLLARVGGNIE

CHD5

1406

Q8TDI0
GVEVQPLRSILVPGL

B4GALNT1

151

Q00973
NGLLLEQPGLRLREP

BNC2

341

Q6ZN30
NLDIVKLLLPRGGSP

ANK1

581

P16157
GPVLAANPGIVGLLL

ARMC2

621

Q8NEN0
LLDPLLPQGAGLRLV

C1QTNF12

136

Q5T7M4
LLLLVAALAGGVRPP

NPR2

6

P20594
LLALLGFILPLPGVQ

CD177

6

Q8N6Q3
VAVPGGVDLLTLPQL

DENND3

31

A2RUS2
VLGLLSLPGVILGAP

ASTL

11

Q6HA08
GGLQLQDLLPLPLQR

ARHGEF39

141

Q8N4T4
SLREPPAGEGIILLQ

ARRDC4

96

Q8NCT1
APQGLLLTDPIERGL

GOLGA7

106

Q7Z5G4
EPRLIVLPNGVLQIL

IGDCC4

186

Q8TDY8
PLAIGLTGQRLLGVP

RBM23

221

Q86U06
RGDPEGQPLLLSLLI

PCDHA9

6

Q9Y5H5
PIGFLELTPLVGLIR

INTS15

231

Q96N11
PTIPIVGIIAGLVLL

HLA-E

301

P13747
LEGTLQPQKRGLPLV

MICAL3

1571

Q7RTP6
RVPVLGSLLNLPGIR

GOLT1B

111

Q9Y3E0
LVLEVPGLAEGRPSL

MOV10L1

566

Q9BXT6
TLVGLEEPLPLAGIR

KTI12

231

Q96EK9
ILVIGLSRELPLGPA

INTS1

656

Q8N201
LIYIIVGLPLPIGTI

ATP12A

806

P54707
VLGIQRPGLLFLPDL

ASPHD1

181

Q5U4P2
LLAGPLGLNDRRIVP

HERC1

3096

Q15751
IPPGIGLLTRLQELI

LRRC39

121

Q96DD0
EELLSGENRGPILLP

DDX56

401

Q9NY93
DVRARLGLPVLPLPQ

CCDC120

166

Q96HB5
GQLPPGLLLLGQSLL

ISLR

406

O14498
LVVPLPGRDLLLVAR

PLXNB3

176

Q9ULL4
ILLGLLEAPGLQPVV

OR3A1

16

P47881
RLEGQETLLGLPPRV

PDZD8

906

Q8NEN9
PRVLETRPALQGLLG

PEX6

136

Q13608
VPAIDLARVLDLGPI

GP2

486

P55259
GLLFELVIVAPLRVP

MARCHF6

736

O60337
GEQLGTVPLPILLAR

MIGA2

81

Q7L4E1
LQVPVGLPFLLILLG

GDPD4

161

Q6W3E5
QLPQRLLPGALRAGI

GDPGP1

176

Q6ZNW5
DALRGLLPVLGQPII

MSLN

246

Q13421
LLGPGPVLTVLALLL

MSLN

611

Q13421
QLLPRGIPEQIGALQ

LRRC8E

71

Q6NSJ5
LLRGLLGQEGPVQPL

AP5B1

171

Q2VPB7
LGQEGPVQPLSLLLA

AP5B1

176

Q2VPB7
LLLVGAPRAEALPLQ

ITGA6

61

P23229
LGVPRQVLALELPEA

PDF

116

Q9HBH1
LLGIAIRADVPLPLD

HECTD4

3706

Q9Y4D8
ALVLGVIQALPVPGL

IRGC

271

Q6NXR0
GPSVLARLLPLLGLL

FAM171A2

6

A8MVW0
LLPALLLVRPAGALV

DNAJC25

26

Q9H1X3
VLVGLVLVPGLLQGP

ATP13A2

1091

Q9NQ11
VLVPGLLQGPLALRN

ATP13A2

1096

Q9NQ11
GLARLVQQRPALPGL

HEATR3

61

Q7Z4Q2
LPPLLARVGGNIEVL

CHD3

1396

Q12873
AAPEVLLQPGRLELG

DENND11

56

A4D1U4
PLLLGLLGLAVAEPA

CALR

6

P27797
GLESPRPNIILGLVI

DIDO1

1181

Q9BTC0
IPPGLVNGLALQLRN

BID

101

P55957
GAQPPLELIRQLLDL

DNAH14

1941

Q0VDD8
VPVRLPALGLGVLQL

MAN2A2

706

P49641
EPGLRLLAVQRLPVG

MALSU1

31

Q96EH3
RSALLLALQPLGPGL

DND1

151

Q8IYX4
LALQPLGPGLQEARL

DND1

156

Q8IYX4
PGLPLVLVLLALGAG

CBLN3

16

Q6UW01
LERLVLALGPLGPQA

COL7A1

1076

Q02388
SIDPVLGPLLGREVI

DNAH9

3516

Q9NYC9
RLLREPGLLAVQGLP

GTF2IRD1

156

Q9UHL9
IPALGLGVCLLLLPG

COCH

6

O43405
LVGIISLPLQIPTLG

RYR1

2466

P21817
DVVPGLIGLIPRISI

IPO13

486

O94829
PLLLDLGIPVGQRSA

MAP3K11

711

Q16584
RQDPPILQVLGRGLV

LRRC43

556

Q8N309
EQLTVLLGLRPNPGL

PKD1

776

P98161
PLPLRDDNGIVLLGE

MTOR

1371

P42345
SVLIANPGLRVPLGR

FREM3

61

P0C091
LPQGLLAGDPRVERL

GAREM2

326

Q75VX8
EPLGELRLPLGTVDL

SYT8

211

Q8NBV8
PQALIDQLKPGGRLI

PCMT1

166

P22061
LVLPVLPGALQARPG

SFTPB

176

P07988
LPALVLLARLGAPAV

MMP23B

31

O75900
VIGLIVPGLILLLRN

SEL1L2

671

Q5TEA6
PGNLEVLLALLVRPG

NBEAL2

1156

Q6ZNJ1
PQLLIPLLGAGLVLG

MPIG6B

141

O95866
LIPYVLIALVGGIPI

SLC6A8

91

P48029
LVRGVLLPGALDGII

SLC6A8

276

P48029
TIALLLEREAGGPLP

SCRIB

941

Q14160
LGTVLVIALNLPPGG

STXBP5

821

Q5T5C0
VIALNLPPGGEQRLL

STXBP5

826

Q5T5C0
LPAVLLRPEGLGALL

NOXO1

286

Q8NFA2
NGLRAVTPLRPGELL

SMYD3

16

Q9H7B4
DPRPLELALLILGVG

SLC45A3

116

Q96JT2
RDNVGLVLLLQPLVP

ANGEL1

361

Q9UNK9
LVLLLQPLVPEGLGQ

ANGEL1

366

Q9UNK9
DLGVLVPLLRDPGLN

CHST7

256

Q9NS84
LPVGQLLELAARPGR

CNNM3

271

Q8NE01
VILVPVRLGGETLNP

ATG4D

301

Q86TL0
VGAGPGLVLAPELLL

RHBDD3

31

Q9Y3P4
ALGDVPNRQPIGIVL

SLC45A4

146

Q5BKX6
GLLLVTGPLVLNRVP

RPL6

171

Q02878
DVSIPLLLRLPLAGG

USP35

826

Q9P2H5
RPQLLLLVGNPRGAL

SLC12A9

531

Q9BXP2
LLVGNPRGALPLLRL

SLC12A9

536

Q9BXP2
ALLLRLVQLAGAPEP

AVP

141

P01185
QLGLRLGEVGVALPL

PRRT4

601

C9JH25
GRILLGPEGVPLQRV

STAB1

611

Q9NY15
ITGGGLLENIPRVLP

GART

681

P22102
LLLLLALGPGVQGCP

VASN

11

Q6EMK4
PLRGSQAPGRIVLLL

ZNF516-DT

21

Q6ZTR6
GPEQILQLGRLLIGL

STRCP1

1521

A6NGW2
GRIRLGPATLNLEVP

UQCRFS1P1

256

P0C7P4
ILELLNQRGLRDPGP

PLEKHG2

546

Q9H7P9
PNAIRLVAPDLGILV

PIEZO1

116

Q92508
LPPRLRQKVAAGLGL

ZC3H10

111

Q96K80
PLGGVILVHLIIPGL

ABI3BP

266

Q7Z7G0
PRLLNLGALIVDPLE

TSPY26P

136

Q9H489
PPGLLVIAPGNRELL

ZHX3

836

Q9H4I2
VPLLLRAIPVGIGQV

SLC14A2

741

Q15849
VLGRVLQLLPPGQVQ

TCIRG1

281

Q13488