Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

EPHB3 MERTK

9.26e-0465142GO:0004714
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

EPHB3 MERTK

1.58e-0385142GO:0019199
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

OGG1 GAA

4.44e-03144142GO:0016798
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

EPHB3 MERTK

4.50e-03145142GO:0004713
GeneOntologyMolecularFunctionprotein kinase activity

EPHB3 MERTK HASPIN

7.67e-03600143GO:0004672
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

EPHB3 MERTK HASPIN

1.21e-02709143GO:0016773
GeneOntologyMolecularFunctionkinase activity

EPHB3 MERTK HASPIN

1.48e-02764143GO:0016301
DomainPkinase_Tyr

EPHB3 MERTK HASPIN

1.11e-04129143PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB3 MERTK HASPIN

1.35e-04138143IPR001245
DomainSAM_1

EPHB3 ANKS1A

1.16e-0368142PF00536
Domain-

EPHB3 CUL7

1.33e-03731422.60.120.260
DomainTyrKc

EPHB3 MERTK

1.93e-0388142SM00219
DomainTyr_kinase_cat_dom

EPHB3 MERTK

1.93e-0388142IPR020635
DomainSAM

EPHB3 ANKS1A

1.93e-0388142SM00454
DomainGalactose-bd-like

EPHB3 CUL7

2.19e-0394142IPR008979
DomainSAM_DOMAIN

EPHB3 ANKS1A

2.24e-0395142PS50105
DomainPROTEIN_KINASE_TYR

EPHB3 MERTK

2.33e-0397142PS00109
DomainSAM

EPHB3 ANKS1A

2.33e-0397142IPR001660
DomainTyr_kinase_AS

EPHB3 MERTK

2.33e-0397142IPR008266
DomainProtein_kinase_ATP_BS

EPHB3 MERTK HASPIN

2.56e-03379143IPR017441
Domain-

EPHB3 ANKS1A

2.78e-031061421.10.150.50
DomainSAM/pointed

EPHB3 ANKS1A

3.37e-03117142IPR013761
DomainPROTEIN_KINASE_ATP

EPHB3 MERTK HASPIN

4.39e-03459143PS00107
DomainProt_kinase_dom

EPHB3 MERTK HASPIN

5.24e-03489143IPR000719
DomainPROTEIN_KINASE_DOM

EPHB3 MERTK HASPIN

5.36e-03493143PS50011
Domainfn3

EPHB3 MERTK

6.35e-03162142PF00041
DomainKinase-like_dom

EPHB3 MERTK HASPIN

6.97e-03542143IPR011009
DomainFN3

EPHB3 MERTK

8.21e-03185142SM00060
DomainFN3

EPHB3 MERTK

9.45e-03199142PS50853
DomainFN3_dom

EPHB3 MERTK

1.04e-02209142IPR003961
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

EPHB3 MERTK

1.16e-044014230898150
Pubmed

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.

GAA ANKS1A

3.48e-046914232238831
InteractionHADHA interactions

MRPS12 REL STT3B CUL7 HASPIN

1.85e-05567135int:HADHA
CytobandEnsembl 112 genes in cytogenetic band chr17p13

USP43 HASPIN

4.85e-03346142chr17p13
CytobandEnsembl 112 genes in cytogenetic band chr6p21

CUL7 ANKS1A

9.99e-03503142chr6p21
GeneFamilySterile alpha motif domain containing

EPHB3 ANKS1A

1.25e-0388112760
GeneFamilyFibronectin type III domain containing

EPHB3 MERTK

4.06e-03160112555
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_k-means-cluster#2_top-relative-expression-ranked_1000

REL NOL4L MERTK

5.59e-05126133gudmap_dev gonad_e11.5_F_GonMes_Sma_k2_1000
ToppCellCOPD-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

REL NOL4L PDE4A

1.97e-051731434a0043b29f8ede5a74bdb38cbf2c70e12b25e130
ToppCellIPF-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

REL NOL4L PDE4A

2.04e-05175143b6d1e40d9339426d778481fd67ab7cbc0f6cb5b2
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

REL GAA MERTK

2.45e-05186143c7e2134454ab5d0885050dd1bb3c3bd15bf497ac
ToppCellnormal_Lymph_Node-T/NK_cells-NK|normal_Lymph_Node / Location, Cell class and cell subclass

USP43 REL PDE4A

2.86e-0519614300ab4a1547752d419aa720b39b94a4ab2ede963a
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

EPHB3 MERTK ANKS1A

2.90e-0519714315b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

EPHB3 MERTK ANKS1A

2.90e-05197143a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellnormal_Lymph_Node-T/NK_cells-NK|T/NK_cells / Location, Cell class and cell subclass

USP43 REL PDE4A

2.95e-0519814375e94298bf03d755fef46df685437d0d29fdbca9
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

REL MERTK

7.94e-04135142b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EPHB3 MERTK

1.00e-03152142ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP43 REL

1.03e-031541421e32969bee810adaf2d560f0824a16227df513d8
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

PDE4A HASPIN

1.04e-03155142b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GAA MERTK

1.08e-031581421635a85fc73c544028418087f36d28957dd4f458
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GAA MERTK

1.08e-0315814280841dadfa53bcde36a3e486408a095f78e772eb
ToppCell(03)_Secretory-(3)_72hpi|(03)_Secretory / shred by cell type and Timepoint

EPHB3 MRPS12

1.08e-0315814220563d03183b63aafc9c389f3f03781140702249
ToppCellmetastatic_Brain-Myeloid_cells-CD1c+_DCs|metastatic_Brain / Location, Cell class and cell subclass

REL PDE4A

1.10e-0315914235a63ca521635389a1edc7c81157793b8ad24d38
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EPHB3 MERTK

1.11e-0316014219105debef96ea0c267d6a1d332303ec668ae47e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB3 REL

1.13e-03161142c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

REL GAA

1.15e-03163142a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REL STT3B

1.20e-031661424b31d2755108b2815316411a38bfb11fd30ef98a
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

REL MERTK

1.24e-031691420867528101767fc65e93b3561480bf830c50368d
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGG1 MERTK

1.24e-0316914215a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GAA MERTK

1.24e-03169142e3100eb587005e160bd0b7990fa57ec49765133d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB3 REL

1.25e-03170142be2a34c70665d8d11332b1a70eda03d77cb7f7dd
ToppCellMild-Treg|World / Disease group and Cell class

USP43 PDE4A

1.25e-03170142f3f177534badca34e1ae8671b7f583ee6688e14b
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REL HASPIN

1.27e-0317114255b194a9bf4d3e4b5d96e0d1298424359c441cbb
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REL HASPIN

1.27e-03171142c6fc9ef9735dbf5314a4c7dac2b2954b0985ae4d
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|368C / Donor, Lineage, Cell class and subclass (all cells)

GAA MERTK

1.30e-03173142bba8265a58f8f5659dc7b9da2fe27b15033fce34
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4A CUL7

1.30e-031731420a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

REL MERTK

1.31e-0317414216204ff504b7b382b4d90ca35003ad5336020e07
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4L MERTK

1.31e-03174142c58328c2f262506a4518f49f148e29874faf9171
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GAA PDE4A

1.31e-03174142062e7bd9072ca7ee68e09b1da28af13f1bc60b44
ToppCell(1)_B_cell-(100)_CD19+_Naive_B_cell|(1)_B_cell / immune cells in Peripheral Blood (logTPM normalization)

MRPS12 REL

1.34e-0317614208bf8485422fce1a4a3b1e7f6b9fab735ce61d46
ToppCell(1)_B_cell-(10)_B_cell-(100)_CD19+_Naive_B_cell|(10)_B_cell / immune cells in Peripheral Blood (logTPM normalization)

MRPS12 REL

1.34e-03176142184f46f01d30630e4bc14eaefb3de9e2a147ccd4
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GAA MERTK

1.36e-03177142382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ANKS1A

1.36e-03177142e1e45956887371b1c18f1eb479dd930031497520
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

OGG1 ANKS1A

1.39e-031791429d51318ac198a8801bd5c7031ebf2b0c74ffeeb6
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|343B / Donor, Lineage, Cell class and subclass (all cells)

PDE4A CUL7

1.39e-03179142c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_4|COVID-19_Convalescent / Disease condition and Cell class

OGG1 ANKS1A

1.39e-03179142366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCellC_00|World / shred on cell type and cluster

EPHB3 MRPS12

1.39e-03179142da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-1|TCGA-Uvea / Sample_Type by Project: Shred V9

MRPS12 GAA

1.40e-031801428f18701fd6e0cc35ed175814e2377d93720c1481
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GAA MERTK

1.40e-031801426f8fa9fa91cd25b92584972bb34d90c483222f52
ToppCellIIH-Treg-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

OGG1 NOL4L

1.43e-031821425c7d02da9ca2bca49db9832704b6894dfaa08a71
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GAA MERTK

1.43e-0318214216186b7a0c33caa48631962381e3ab7e5d166163
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

REL MERTK

1.45e-03183142614a1c08cf6d01a4f1ed2fb816cd1a6e0c3207ce
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PDE4A CUL7

1.45e-031831423cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB3 PDE4A

1.47e-03184142d754c3de621429b220ae4ac426cdfc619e848462
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL PDE4A

1.47e-03184142b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

REL PDE4A

1.48e-031851424a5e70ac41e5f3b25a773304ffef3c2a3dd5549d
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PDE4A CUL7

1.50e-03186142bca5215d406f1785bf3a420201d5686071fcaca5
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

REL PDE4A

1.53e-031881426686dbba990066568aa7573e70a7db8b4758f457
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GAA MERTK

1.53e-031881423f47395db7e6159fc95810545bad4b6e028464c5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GAA MERTK

1.53e-03188142e32d95f8e86111245d7f4b5fd72d2471fe0f1304
ToppCell3'_v3-GI_small-bowel|World / Manually curated celltypes from each tissue

REL PDE4A

1.53e-03188142822c6abaf7bcd6721269bdbd1f2b286ccf0aec1a
ToppCellfacs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAA ANKS1A

1.55e-03189142533685a921a65d84107d8d33c43b4fffde019143
ToppCellfacs-Marrow-KLS-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAA ANKS1A

1.55e-03189142dca56ab02bf0505f9a352ff907edaef30906d854
ToppCell(1)_T_cells-(1)_T_CD8_gd|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

REL PDE4A

1.56e-03190142268772d2adff34f7175b8474e95b67fd96dc1234
ToppCellControl-Myeloid-cDC2|Control / Disease state, Lineage and Cell class

REL PDE4A

1.56e-031901424e481e42353d47af7991744000403af2873f6a41
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GAA MERTK

1.56e-031901420a944da2aaaef9289b2a4ffe360b0338724fd59b
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MERTK ANKS1A

1.56e-03190142f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellBLOOD--(2)_B_cell-(2)_Naive_B_cells|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MRPS12 REL

1.56e-03190142bde288cea27bbdc3ca05737a00fe30a0103a4c74
ToppCellNS-critical-d_16-33-Myeloid-Non-resident_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDE4A MERTK

1.56e-031901424fe9654a9b449ef49ca10b973ac4378dab34cb53
ToppCellfacs-Marrow-KLS-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAA ANKS1A

1.56e-03190142a513c1e7df62c28128c932a68b252ee8f0255172
ToppCellControl-Myeloid-cDC2|World / Disease state, Lineage and Cell class

REL PDE4A

1.58e-0319114211dfd8f38beb294f42710cfbd355cb089e1023c0
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

REL PDE4A

1.58e-031911422af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellIPF-Myeloid-cDC2|World / Disease state, Lineage and Cell class

REL PDE4A

1.58e-031911429fda87fb6bc5b8b6c0214ec909ebbc9f3f65319b
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

REL PDE4A

1.58e-031911424e4887175200a57e1b041f2f131e3df774df3509
ToppCellIPF-Myeloid-cDC2|IPF / Disease state, Lineage and Cell class

REL PDE4A

1.59e-03192142fe1de692fec48cba4a9bbc6eaa257260e8b4e800
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

REL PDE4A

1.59e-03192142984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAA ANKS1A

1.59e-0319214203dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCellBAL-Control-Myeloid-MoAM-MoAM3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

REL MERTK

1.61e-03193142837c61408462c519912ecf3b83fdc72cd85fe88f
ToppCellControl-Myeloid-MoAM3|Control / Disease group,lineage and cell class （2021.01.30）

REL MERTK

1.61e-0319314297d2f12be43fc26efa84ac4c6119132928a123de
ToppCellCTRL-Myeloid-Alveolar_Macrophage|Myeloid / Disease state, Lineage and Cell class

GAA ANKS1A

1.61e-0319314280871d963c23a6befe58e5e60b7f7d1a1b227ce2
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CCL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRPS12 PDE4A

1.61e-0319314221a117cceb562439ca3fe129aad8cac5f5728b1f
ToppCellControl-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

REL PDE4A

1.61e-031931424cb938c346cc32ec122d11e6b9f25db20e0f7ff6
ToppCellBAL-Control-Myeloid-MoAM-MoAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

REL MERTK

1.61e-03193142e54f8b6381b5a96758cff41ab12d6f60cfca29a9
ToppCellBAL-Control-Myeloid-MoAM-MoAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

REL MERTK

1.61e-03193142e4ca3a3c2704cdc52e6ac3f25f14debf74226c29
ToppCellBAL-Control-Myeloid-MoAM-MoAM3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

REL MERTK

1.61e-03193142d81840e1322507552b7726bf7828309375162324
ToppCellIPF-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

REL PDE4A

1.63e-03194142accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE4A MERTK

1.63e-031941423043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellCD8+_Memory_T_cell-CV-6|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

REL PDE4A

1.63e-0319414235a347c3824757b9de8b7f49db46e73e7fb63a4f
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

REL PDE4A

1.63e-03194142bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCell10x5'-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

USP43 PDE4A

1.63e-031941425c58a2d1dd3c8ff77ce44d473239685e6b020909
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MERTK ANKS1A

1.63e-0319414245708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GAA MERTK

1.63e-03194142449ce4167d64c170d914e0250f739eabedcf915d
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB3 USP43

1.63e-031941420ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCell3'_v3-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

REL PDE4A

1.64e-031951421470f562ebcfe7da367964ecfd6c7f43bcdb4a73
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OGG1 REL

1.64e-03195142cccc9c70bb8f6df8c6ab94534c17475af1d3e224
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MERTK ANKS1A

1.64e-03195142247803cf58c6d9c561a52aa34e581188ddad197e
ToppCellMacrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

GAA MERTK

1.64e-03195142eb104f3bb08ab9eca31273c0523a5c90de1f30a9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

REL MERTK

1.64e-03195142fa8ac154e5aebc26463ff84f0ad1038095770bc6
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

REL MERTK

1.64e-03195142562e4c0e4e81f6303e57b846da71d1667fc35963
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

REL PDE4A

1.64e-0319514262dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAA MERTK

1.64e-031951425a7c74f96f213c504abd65e751800da7e03e47d9
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

GAA MERTK

1.64e-0319514210fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL PDE4A

1.66e-03196142c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Dendritic_cells|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

REL PDE4A

1.66e-03196142f278b144b8deaee0bf41682081b9fbb0b1e82b19
ToppCell(7)_MNP-(7)_Macrophage|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MRPS12 MERTK

1.66e-0319614271ec157163278ad259c190051926bf41e4ecef46
ToppCell(2)_B_cells-(2)_B_cells|(2)_B_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MRPS12 REL

1.66e-031961427b7338b9caeb05b78f4c88a89d41b4bece0b2bab
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB3 USP43

1.66e-0319614222fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL PDE4A

1.66e-0319614264c2abc0087bf2ae547932377f3662e3be1cc63e
DrugArtemisinin [63968-64-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A

EPHB3 MRPS12 OGG1 ANKS1A

5.19e-061981447007_DN
DrugAC1L1A8Z

REL MERTK

3.18e-0514142CID000000885
DrugDB07570

REL MERTK

1.22e-0427142CID004369534
DrugAC1L970Z

GAA STT3B

1.41e-0429142CID000439275
Drugchlorophyllin

MRPS12 OGG1

1.62e-0431142CID000123798
Drugremifentanil

MERTK ANKS1A

1.72e-0432142CID000060814
Drugdaunorubicin HCl; Up 200; 1uM; MCF7; HT_HG-U133A

EPHB3 PDE4A MERTK

1.74e-041831437507_UP
Drug2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA

EPHB3 OGG1 PDE4A

1.86e-041871431047_UP
DrugGramine [87-52-5]; Up 200; 23uM; HL60; HT_HG-U133A

MRPS12 PDE4A MERTK

1.95e-041901432143_UP
Drugisopentenyladenosine

MRPS12 REL

1.95e-0434142CID000024405
DrugICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

EPHB3 REL CUL7

2.01e-041921431076_UP
DrugGalanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; HL60; HT_HG-U133A

MRPS12 CUL7 MERTK

2.04e-041931432131_UP
DrugColchicine [64-86-8]; Down 200; 10uM; MCF7; HT_HG-U133A

MRPS12 PDE4A MERTK

2.04e-041931433213_DN
DrugSulindac [38194-50-2]; Up 200; 11.2uM; HL60; HT_HG-U133A

MRPS12 PDE4A CUL7

2.10e-041951431857_UP
DrugTiaprofenic acid [33005-95-7]; Down 200; 15.4uM; MCF7; HT_HG-U133A

EPHB3 PDE4A CUL7

2.10e-041951432852_DN
DrugButoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A

EPHB3 PDE4A CUL7

2.10e-041951433288_DN
DrugRapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A

EPHB3 OGG1 CUL7

2.10e-041951436180_DN
Drugalpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A

EPHB3 OGG1 ANKS1A

2.13e-041961436970_DN
Drugclozapine; Down 200; 10uM; MCF7; HT_HG-U133A

EPHB3 CUL7 ANKS1A

2.13e-041961436988_DN
DrugPhenformin hydrochloride [834-28-6]; Up 200; 16.6uM; PC3; HT_HG-U133A

EPHB3 CUL7 MERTK

2.13e-041961434283_UP
DrugBudesonide [51333-22-3]; Down 200; 9.2uM; PC3; HT_HG-U133A

EPHB3 MRPS12 REL

2.13e-041961436330_DN
DrugN6-methyladenosine [1867-73-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A

MRPS12 OGG1 ANKS1A

2.16e-041971435332_DN
Drugfluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

EPHB3 OGG1 CUL7

2.16e-041971435597_DN
DrugGossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A

EPHB3 OGG1 PDE4A

2.20e-041981434762_DN
DrugTrihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; HL60; HT_HG-U133A

EPHB3 MRPS12 PDE4A

2.20e-041981432158_UP
DrugAntipyrine [60-80-0]; Up 200; 21.2uM; MCF7; HT_HG-U133A

PDE4A CUL7 MERTK

2.20e-041981431489_UP
DrugDO 897/99; Down 200; 8.2uM; MCF7; HT_HG-U133A

EPHB3 MRPS12 PDE4A

2.20e-041981432877_DN
DrugFlunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A

EPHB3 MRPS12 OGG1

2.20e-041981437412_DN
DrugLincomycin hydrochloride [859-18-7]; Down 200; 9uM; HL60; HT_HG-U133A

OGG1 PDE4A CUL7

2.20e-041981432380_DN
DrugIsopropamide iodide [71-81-8]; Down 200; 8.4uM; PC3; HT_HG-U133A

MRPS12 REL GAA

2.23e-041991437133_DN
Drugchlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A

EPHB3 MRPS12 OGG1

2.23e-041991436977_DN
DrugBromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A

EPHB3 PDE4A CUL7

2.23e-041991434741_DN
DrugIsoxicam [34552-84-6]; Down 200; 12uM; PC3; HT_HG-U133A

EPHB3 OGG1 PDE4A

2.26e-042001437268_DN
Drugdeoxyfuconojirimycin

GAA STT3B

2.31e-0437142CID000122618
DrugNi-Fe active center

OGG1 REL

2.57e-0439142CID005195770
DrugU-U-U

MRPS12 GAA

2.84e-0441142CID005289515
DrugQ U I

MRPS12 REL

3.13e-0443142CID000078857
DrugLithium

OGG1 REL PDE4A

4.15e-04246143ctd:D008094
Drug4-hydroxy-equilenin

MRPS12 GAA

4.75e-0453142ctd:C065250
Drugactinorhodin

MRPS12 REL

6.09e-0460142CID005280985
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

OGG1 CUL7 MERTK

4.32e-05148143C0279702
DiseasePapillary Renal Cell Carcinoma

OGG1 CUL7

1.64e-03128142C1306837
DiseaseRenal Cell Carcinoma

OGG1 CUL7

1.64e-03128142C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

OGG1 CUL7

1.64e-03128142C1266043
DiseaseChromophobe Renal Cell Carcinoma

OGG1 CUL7

1.64e-03128142C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

OGG1 CUL7

1.64e-03128142C1266044
Diseasebreast cancer (is_marker_for)

OGG1 REL

3.39e-03185142DOID:1612 (is_marker_for)
Diseaseplatelet component distribution width

NOL4L GAA ANKS1A

4.92e-03755143EFO_0007984
Diseaseopioid dependence

EPHB3 OGG1

5.49e-03237142EFO_0005611
DiseaseAutistic Disorder

PDE4A CUL7

6.61e-03261142C0004352
Diseaseplatelet crit

NOL4L GAA PDE4A

9.34e-03952143EFO_0007985

Protein segments in the cluster

PeptideGeneStartEntry
SSSHPLSSLLSMWRG

ANKS1A

56

Q92625
GVSWSHSSMLPLGSS

MERTK

966

Q12866
TTRMSWPSSFHGTGT

PDE4A

81

P27815
DWSSLATRGLPSSIM

CUL7

1126

Q14999
LHSSSGSSLTLSWAP

EPHB3

461

P54753
MGHRTLASTPALWAS

OGG1

11

O15527
WMSADPHLASSLSPS

NOL4L

6

Q96MY1
MPSSLATRLAAASWG

OR6P1

136

Q8NGX9
AEHLSPLMLSTSWTR

GAA

261

P10253
GAPSSWHSSSMYLLS

HASPIN

431

Q8TF76
MSWSGLLHGLNTSLT

MRPS12

1

O15235
SMRGSTSSSLSDHWL

USP43

721

Q70EL4
HKSSLNSSPWSGLMA

STT3B

11

Q8TCJ2
HASMAPLPSSSWSSV

REL

401

Q04864