Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of mRNA splicing, via spliceosome

RBMY1A1 RBMY1C RBMY1F

6.69e-0544373GO:0048026
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

RBMY1A1 RBMY1C HNRNPL RBMY1F

8.22e-05129374GO:0048024
GeneOntologyBiologicalProcesspositive regulation of mRNA processing

RBMY1A1 RBMY1C RBMY1F

9.25e-0549373GO:0050685
GeneOntologyBiologicalProcessleukocyte migration

SMPD3 LCK MMP9 ITGA7 ADAM8 CD99L2

1.35e-04449376GO:0050900
GeneOntologyBiologicalProcesspositive regulation of neutrophil extravasation

ADAM8 CD99L2

1.40e-0410372GO:2000391
GeneOntologyBiologicalProcessregulation of neutrophil extravasation

ADAM8 CD99L2

1.70e-0411372GO:2000389
GeneOntologyBiologicalProcessregulation of mRNA processing

RBMY1A1 RBMY1C HNRNPL RBMY1F

1.80e-04158374GO:0050684
GeneOntologyBiologicalProcesspositive regulation of RNA splicing

RBMY1A1 RBMY1C RBMY1F

1.96e-0463373GO:0033120
GeneOntologyBiologicalProcessartery smooth muscle contraction

GRIP2 SMPD3

2.41e-0413372GO:0014824
GeneOntologyBiologicalProcessresponse to redox state

SMPD3 RYR2

2.81e-0414372GO:0051775
GeneOntologyBiologicalProcesstonic smooth muscle contraction

GRIP2 SMPD3

3.24e-0415372GO:0014820
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

RBMY1A1 RBMY1C HNRNPL RBMY1F DDX42

4.23e-04358375GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

RBMY1A1 RBMY1C HNRNPL RBMY1F DDX42

4.23e-04358375GO:0000377
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

RBMY1A1 RBMY1C HNRNPL RBMY1F DDX42

4.45e-04362375GO:0000375
GeneOntologyBiologicalProcessneutrophil extravasation

ADAM8 CD99L2

4.70e-0418372GO:0072672
GeneOntologyBiologicalProcessregulation of RNA splicing

RBMY1A1 RBMY1C HNRNPL RBMY1F

5.02e-04207374GO:0043484
GeneOntologyBiologicalProcessextracellular matrix organization

COL24A1 SMPD3 MMP9 ADAM8 MMP17

5.35e-04377375GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

COL24A1 SMPD3 MMP9 ADAM8 MMP17

5.42e-04378375GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

COL24A1 SMPD3 MMP9 ADAM8 MMP17

5.48e-04379375GO:0045229
DomainRBM1CTR

RBMY1A1 RBMY1F

1.00e-048362PF08081
DomainRBM1CTR

RBMY1A1 RBMY1F

1.00e-048362IPR012604
DomainMetalloPept_cat_dom

MMP9 ADAM8 MMP17

5.06e-0481363IPR024079
Domain-

MMP9 ADAM8 MMP17

5.06e-04813633.40.390.10
DomainCollagen

C1QB COL24A1 C1QTNF2

5.83e-0485363IPR008160
DomainCollagen

C1QB COL24A1 C1QTNF2

5.83e-0485363PF01391
DomainPG_binding_1

MMP9 MMP17

6.72e-0420362PF01471
DomainPeptidoglycan-bd-like

MMP9 MMP17

6.72e-0420362IPR002477
DomainZINC_PROTEASE

MMP9 ADAM8 MMP17

8.82e-0498363PS00142
DomainHemopexin-like_dom

MMP9 MMP17

8.91e-0423362IPR000585
DomainHemopexin-like_repeat

MMP9 MMP17

8.91e-0423362IPR018487
DomainM10A_MMP

MMP9 MMP17

8.91e-0423362IPR033739
DomainHemopexin

MMP9 MMP17

8.91e-0423362PF00045
DomainHEMOPEXIN

MMP9 MMP17

8.91e-0423362PS00024
Domain-

MMP9 MMP17

8.91e-04233622.110.10.10
DomainHEMOPEXIN_2

MMP9 MMP17

8.91e-0423362PS51642
DomainHX

MMP9 MMP17

8.91e-0423362SM00120
DomainPept_M10A

MMP9 MMP17

8.91e-0423362IPR021190
DomainPeptidase_M10

MMP9 MMP17

9.71e-0424362PF00413
DomainZnMc

MMP9 MMP17

1.42e-0329362SM00235
DomainPeptidase_Metallo

MMP9 MMP17

1.42e-0329362IPR006026
DomainC1Q

C1QB C1QTNF2

1.73e-0332362SM00110
DomainC1q

C1QB C1QTNF2

1.73e-0332362PF00386
DomainC1q_dom

C1QB C1QTNF2

1.95e-0334362IPR001073
DomainC1Q

C1QB C1QTNF2

1.95e-0334362PS50871
DomainCYSTEINE_SWITCH

MMP9 MMP17

2.83e-0341362PS00546
DomainPept_M10_metallopeptidase

MMP9 MMP17

3.10e-0343362IPR001818
Domain-

C1QB C1QTNF2

4.18e-03503622.60.120.40
DomainTumour_necrosis_fac-like_dom

C1QB C1QTNF2

5.58e-0358362IPR008983
DomainRRM_1

RBMY1A1 HNRNPL RBMY1F

7.42e-03208363PF00076
DomainRRM

RBMY1A1 HNRNPL RBMY1F

8.33e-03217363SM00360
DomainConA-like_dom

COL24A1 RYR2 NRP1

8.54e-03219363IPR013320
Pubmed

A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.

RBMY1A1 RBMY1C RBMY1F

3.87e-0873738269511
Pubmed

Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.

RBMY1A1 RBMY1C RBMY1F

2.42e-07123739598316
Pubmed

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.

RBMY1A1 RBMY1C RBMY1F

3.15e-071337310749975
Pubmed

Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression.

MMP9 ADAM8

1.10e-06237224526468
Pubmed

NRP1 and MMP9 are dual targets of RNA-binding protein QKI5 to alter VEGF-R/ NRP1 signalling in trophoblasts in preeclampsia.

MMP9 NRP1

1.10e-06237233942999
Pubmed

ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells.

MMP9 ADAM8

1.10e-06237228986926
Pubmed

ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9.

MMP9 ADAM8

3.30e-06337235216088
Pubmed

[Study on relationship between constitution and syndrome of MMP-9, IL-6 and MTHFR gene in patients with ischemic stroke].

MMP9 MTHFR

3.30e-06337229218949
Pubmed

Phosphorylation of FOXP3 by LCK downregulates MMP9 expression and represses cell invasion.

LCK MMP9

3.30e-06337224155921
Pubmed

Polymorphisms in the MTHRF, VDR, MMP-9 and IL-β genes and the risk of premature rupture of membranes.

MMP9 MTHFR

6.60e-06437220639647
Pubmed

Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis.

MMP9 MTHFR

1.65e-05637217920311
Pubmed

RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.

RBMY1A1 RBMY1F

1.65e-05637215184870
Pubmed

Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene.

RBMY1A1 RBMY1F

2.30e-0573728875892
Pubmed

The genetics of abdominal aortic aneurysms: a comprehensive meta-analysis involving eight candidate genes in over 16,700 patients.

MMP9 MTHFR

3.07e-05837220302034
Pubmed

Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif.

BSN NRP1

3.07e-05837215978582
Pubmed

Impact of donor-dependent genetic factors on long-term renal graft function.

MMP9 MTHFR

3.95e-05937219857655
Pubmed

T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.

RBMY1A1 RBMY1C

4.93e-051037210332027
Pubmed

Genetic variation associated with preterm birth: a HuGE review.

MMP9 MTHFR

6.02e-051137216301860
Pubmed

Assignment of the mouse homologues of 6 loci from HSA1p to chromosomes 3 and 4.

C1QB LCK

8.53e-05133727829080
Pubmed

Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

MMP9 NRP1

1.15e-041537211804779
Pubmed

Matrix metalloproteinases in tumor invasion.

MMP9 MMP17

1.31e-041637210949577
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

COL24A1 SMPD3 RBMY1A1

1.43e-049537324029230
Pubmed

A molecular analysis of matrix remodeling and angiogenesis during long bone development.

MMP9 NRP1

1.48e-041737211165481
Pubmed

Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3).

MAPK8IP3 NRP1

2.07e-042037212897243
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP9 MMP17

2.51e-042237223421805
Pubmed

Matrix metalloproteinases.

MMP9 MMP17

2.51e-042237210419448
Pubmed

APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.

MOXD1 MMP9

2.75e-042337225920569
Pubmed

Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.

MMP9 MMP17

2.99e-042437215734845
Pubmed

Preferred SH3 domain partners of ADAM metalloproteases include shared and ADAM-specific SH3 interactions.

LCK ADAM8

2.99e-042437225825872
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

MOXD1 CD99L2 NRP1 DDX42

3.13e-0430737437499664
Pubmed

Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation.

MMP9 NRP1

3.52e-042637220978081
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

MIDEAS HNRNPL DDX42

5.28e-0414837332538781
Pubmed

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.

MMP9 ITGA7

5.35e-043237223154389
Pubmed

Characterization of long cDNA clones from human adult spleen.

GRIP2 MAPK8IP3

5.69e-043337211214971
Pubmed

LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.

MMP9 RYR2

6.05e-043437226378152
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

MMP9 MMP17

6.78e-043637220587546
Pubmed

Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate.

MMP9 MTHFR

6.78e-043637220672350
Pubmed

The identification of myocilin-associated proteins in the human trabecular meshwork.

C1QB ITGA7

9.23e-044237216289162
Pubmed

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).

MMP9 MMP17 MTHFR

1.02e-0318637320673868
Pubmed

Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

MMP9 MMP17 MTHFR

1.02e-0318637320452482
InteractionCOL4A2 interactions

FKBP9 C1QB C1QTNF2 MMP9

1.06e-0575374int:COL4A2
Cytoband17q23.3

SCN4A DDX42

2.71e-043037217q23.3
Cytoband1p34.3

LCK EPHA10

1.16e-03623721p34.3
CytobandEnsembl 112 genes in cytogenetic band chr17q25

CDC42EP4 ST6GALNAC2 RECQL5

1.94e-03307373chr17q25
CytobandYq11.223

RBMY1A1 RBMY1F

2.58e-0393372Yq11.223
CytobandEnsembl 112 genes in cytogenetic band chr17q23

SCN4A DDX42

4.25e-03120372chr17q23
GeneFamilyRNA binding motif containing

RBMY1A1 RBMY1C HNRNPL RBMY1F

4.04e-04213304725
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP9 MMP17

7.18e-0424302891
CoexpressionHARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_28DY_POSITIVE

FKBP9 XXYLT1 BHLHE41 TUBB6 COL24A1 SMPD3 CDC42EP4 MMP9 MIDEAS ST6GALNAC2 SBF2 NRP1

5.67e-0812503612M41099
CoexpressionFLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP

C1QB MOXD1 LCK MMP9

6.44e-0688364M19695
CoexpressionXIE_TRASTUZUMAB_CARDIOTOXICITY_MMU_MIR_483_5P_GENES

HLCS MAPK8IP3

1.00e-0411362MM17503
CoexpressionGSE360_L_DONOVANI_VS_L_MAJOR_DC_DN

ADAM8 MTHFR HNRNPL RECQL5

1.48e-04196364M5194
CoexpressionGSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP

FKBP9 HLCS C1QB ST6GALNAC2

1.57e-04199364M6420
CoexpressionACEVEDO_METHYLATED_IN_LIVER_CANCER_DN

C1QB COL24A1 EPHA10 RBMY1A1 SBF2 RBMY1F DDX42

1.59e-04873367M16009
CoexpressionGSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN

FKBP9 TUBB6 C1QB NRP1

1.60e-04200364M4612
CoexpressionGSE13306_RA_VS_UNTREATED_TCONV_UP

XXYLT1 MIDEAS ST6GALNAC2 SCN4A

1.60e-04200364M3234
CoexpressionGSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN

C1QB CDC42EP4 ADAM8 NRP1

1.60e-04200364M9668
CoexpressionGSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN

FKBP9 TUBB6 ADAM8 NRP1

1.60e-04200364M9680
CoexpressionGSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_DN

FKBP9 MTHFR ST6GALNAC2 NRP1

1.60e-04200364M8217
CoexpressionGSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_UP

BHLHE41 LSS MMP9 NRP1

1.60e-04200364M9909
CoexpressionGSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN

BHLHE41 LSS MMP17 DDX42

1.60e-04200364M4108
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3

FKBP9 BHLHE41 TUBB6 C1QB ADAM8 SBF2 NRP1

7.88e-06441367GSM605862_500
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

TUBB6 COL24A1 SMPD3 RECQL5 NRP1

2.35e-07168365dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_CTXN3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL24A1 MOXD1 ITGA7 EPHA10 NRP1

3.04e-0717736596d639407f79669f3990138793d157b94273581c
ToppCellIIH-pDC-|IIH / Condition, Cell_class and T cell subcluster

TUBB6 COL24A1 MOXD1 SMPD3 NRP1

3.99e-07187365ad87b146ea8dd9f695e722f8f0e8e1057c7f3167
ToppCellIIH-pDC|IIH / Condition, Cell_class and T cell subcluster

TUBB6 COL24A1 MOXD1 SMPD3 NRP1

3.99e-071873655e59e9153a18bcfb5c8dc94599080216661de7ce
ToppCellMS-pDC-|MS / Condition, Cell_class and T cell subcluster

TUBB6 COL24A1 SMPD3 RECQL5 NRP1

4.32e-07190365f56ec302d556ace4f7609017a35c311cf43aa8a5
ToppCellMS-pDC|MS / Condition, Cell_class and T cell subcluster

TUBB6 COL24A1 SMPD3 RECQL5 NRP1

4.32e-07190365f41d7ab7d7fbcd73fddb6c3533c6a3e642e3d07f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 C1QTNF2 GRIP2 ITGA7 RYR2

4.43e-0719136504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK MMP9 ITGA7 ADAM8

9.37e-06165364651d40eadb1b34de618af94c167f43635729d43f
ToppCell-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL24A1 MOXD1 SMPD3 LCK

1.05e-05170364601630644f09133ee4c5e64499460b55cf3e80a0
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

TUBB6 COL24A1 SMPD3 NRP1

1.08e-0517136472c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MOXD1 GRIP2 MMP17 ST6GALNAC2

1.13e-05173364789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 C1QTNF2 MMP17 ST6GALNAC2

1.16e-051743649c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 C1QTNF2 MMP17 ST6GALNAC2

1.16e-05174364bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellIIF-Myeloid-pDC|IIF / Disease, Lineage and Cell Type

TUBB6 COL24A1 SMPD3 NRP1

1.18e-0517536435cfb7d0b88678ff5b83ad6e19dbc15a908a3fcc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

C1QTNF2 GRIP2 ITGA7 RYR2

1.18e-05175364316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

C1QTNF2 GRIP2 ITGA7 RYR2

1.18e-05175364a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 COL24A1 RYR2 SCN4A

1.21e-05176364c6484334187f64cd00cd35e77d8ae436556b4260
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

COL24A1 SMPD3 RECQL5 NRP1

1.21e-05176364ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUBB6 COL24A1 SMPD3 NRP1

1.29e-05179364124da6f882968dc0d05f3edd8f3b4d61617cc214
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUBB6 COL24A1 SMPD3 NRP1

1.29e-05179364edc5ef693dc4e7ea70717b77fb908fc784dce3a2
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUBB6 COL24A1 SMPD3 NRP1

1.41e-051833643b123571e10c132227aff65648b4b3c6acb4bd00
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUBB6 COL24A1 SMPD3 NRP1

1.41e-05183364df6fd0927b6e4cf9a1583969a68096e4bccfbace
ToppCellcontrol-Myeloid-pDC|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TUBB6 COL24A1 SMPD3 NRP1

1.50e-05186364fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TUBB6 COL24A1 SMPD3 NRP1

1.50e-05186364a07694caf7fede06a47636725bcc7f09909cdf07
ToppCellMultiple_Sclerosis-Myeloid-pDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

TUBB6 COL24A1 SMPD3 NRP1

1.50e-05186364330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

TUBB6 COL24A1 SMPD3 NRP1

1.50e-05186364916f2aeea4989ba7a29e071e348a51010f010223
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|Dendritic_cell / Lineage, cell class and subclass

COL24A1 SMPD3 RECQL5 NRP1

1.50e-05186364858134580a09ed8a5eb6d6413d8ca9265904dfc1
ToppCellcontrol-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

COL24A1 MOXD1 SMPD3 NRP1

1.50e-05186364fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCellhealthy_donor-Lymphocytic-Dendritic-pDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

TUBB6 COL24A1 SMPD3 NRP1

1.50e-0518636445f66619e45d590c7365a51782d4ac46b7d31fde
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK BSN EPHA10 RYR2

1.50e-051863647278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MOXD1 SMPD3 ITGA7 MMP17

1.53e-051873646f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF2 GRIP2 ITGA7 MMP17

1.53e-05187364dba4924d914a7dcd4901142684ba920c2404860b
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF2 GRIP2 ITGA7 MMP17

1.53e-051873649688141beef4f62613d7a810c5872ccb9afc1a71
ToppCellLeuk-UTI-Myeloid-pDC|Leuk-UTI / Disease, Lineage and Cell Type

TUBB6 COL24A1 SMPD3 NRP1

1.53e-05187364e3035b1f65ab12b8f01799b8e5d6633b9b584a06
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|normal_Lymph_Node / Location, Cell class and cell subclass

FKBP9 C1QB MMP9 NRP1

1.57e-05188364e83de94a9b47a6a90e98face887eae031a322af6
ToppCellControl-Myeloid-pDC|Control / Disease group, lineage and cell class

TUBB6 COL24A1 SMPD3 NRP1

1.60e-0518936446770b99da42f11f10cfc67cea8562342d60b867
ToppCellPBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TUBB6 COL24A1 SMPD3 NRP1

1.63e-05190364adffa93635da10251f28b2089fd96b189775c8b4
ToppCellPBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TUBB6 COL24A1 SMPD3 NRP1

1.63e-051903649a91bf1ea105029e6412d0d9060bca325299ce26
ToppCellPBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TUBB6 COL24A1 SMPD3 NRP1

1.63e-0519036439c8ddc2639bf3e986dae11fbae61a735614b604
ToppCellPBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TUBB6 COL24A1 SMPD3 NRP1

1.63e-051903642c1c079fd411c03bc3f383aa927eea9446716960
ToppCellPBMC-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TUBB6 COL24A1 SMPD3 NRP1

1.63e-05190364a95aea3aa707fc4574810706341a5f32b3d00209
ToppCellPBMC-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TUBB6 COL24A1 SMPD3 NRP1

1.63e-0519036418dfa84c62dcf081ce9958a71e76a394ec0968e4
ToppCellCOVID-19_Moderate-pDC|COVID-19_Moderate / disease group, cell group and cell class

TUBB6 COL24A1 SMPD3 NRP1

1.67e-051913649d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCellHealthy-pDC|World / disease group, cell group and cell class

TUBB6 COL24A1 SMPD3 NRP1

1.67e-051913646e1d825dc33b915b95f13ccd237a552160a4be98
ToppCellHealthy-pDC|Healthy / disease group, cell group and cell class

TUBB6 COL24A1 SMPD3 NRP1

1.70e-0519236433d695a28d22b4af111df9591830a33bb7ef7b2d
ToppCellVE-pDC-|VE / Condition, Cell_class and T cell subcluster

TUBB6 COL24A1 SMPD3 NRP1

1.74e-05193364583724de588fcde3aeda056138c522dc0225a387
ToppCellVE-pDC|VE / Condition, Cell_class and T cell subcluster

TUBB6 COL24A1 SMPD3 NRP1

1.74e-05193364bb759dc9ef0ec41d655002f59021d62d62d44289
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

TUBB6 COL24A1 SMPD3 NRP1

1.77e-0519436474545942aded51a0f4ee96054b4ce12c4d99a8a0
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

COL24A1 MOXD1 RYR2 NRP1

1.88e-05197364f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MOXD1 GRIP2 MMP17 ST6GALNAC2

1.92e-0519836436c97eb71b89bac01cabd6a8b728e5a20e52d2a3
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MOXD1 CDC42EP4 MMP17 ST6GALNAC2

1.92e-0519836450dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDC42EP4 MMP9 ST6GALNAC2

1.24e-0412036316c3bd15e3936b68c433c4dd15d655aae64dc960
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TUBB6 C1QTNF2 ITGA7

2.08e-041433639bfb3674c8f011b9cf928b522777b8d54478db8d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BHLHE41 TUBB6 ST6GALNAC2

2.12e-04144363fca32b38d23fa4d213e553b929604a2796e9a929
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MTHFR RECQL5 MAPK8IP3

2.30e-0414836310dcbdb47cac908648d9d652c8095b536db19b8a
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1QB RYR2 MAPK8IP3

2.30e-041483635983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L6_NP_ALM_Trh|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL24A1 ITGA7 NRP1

2.35e-04149363fe9dff31a30dabd212d53d1295f9f13ff32cb217
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA7 MMP17 NRP1

2.44e-04151363f50c5ae9dae507df750df25e151b58685fec70ce
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

C1QTNF2 ITGA7 RYR2

2.49e-04152363bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_3|390C / Donor, Lineage, Cell class and subclass (all cells)

BHLHE41 C1QB MMP9

2.49e-04152363f717aae4882e9b67e5e40f4ef5b0d35f74a89165
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

C1QTNF2 ITGA7 RYR2

2.49e-04152363ee329249a034a969a16b26a224aa04249d67382d
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK MMP9 ADAM8

2.54e-04153363cb144b8c487286384b47fdff88ff98fcf0508899
ToppCellBAL-Control-cDC_12|Control / Compartment, Disease Groups and Clusters

SMPD3 CDC42EP4 LRP11

2.58e-041543630121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA7 MMP17 RYR2

2.68e-041563636365b69ede98bc866e996bc52736b00401aacf6f
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.73e-04157363c8f516d3f5622202d3f8514f68614cd86ea3f667
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.73e-041573634862a11ab8df27d26b4f1c1785e544a2d5b6db6e
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.73e-04157363c3451b33780499fd62672e7cd71c7e8cb6ccc2c5
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BHLHE41 C1QB C1QTNF2

2.73e-04157363d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.73e-0415736392cd58b62e46b93f90e05657fd201404ccae6ddb
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.73e-04157363042129d1b514dc4ed8a5f45b52d9c73cf4807636
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.73e-04157363a0ec1628ce29841889f1d9d4ee9422921af7b0b5
ToppCelldroplet-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.79e-04158363e1a8dba5a88bc3ce112829c5ecb112cbbee5b078
ToppCelldroplet-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.79e-0415836372e4f8ae137a7dddee0dc6236532e0711065e6af
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MOXD1 C1QTNF2 SCN4A

2.84e-04159363cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL24A1 MMP9 NRP1

2.84e-041593634b840da854390f8285c219314cff4434d7ffcacc
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL24A1 MMP9 NRP1

2.84e-04159363d9e535cf9a0a2302268f2897b010dcecc6426e41
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL24A1 MMP9 NRP1

2.84e-0415936329999c87f5823f734e5cbf8ea8b729ec017db9b3
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB RYR2 SCN4A

2.89e-04160363f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

COL24A1 SMPD3 NRP1

2.89e-0416036361f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

COL24A1 SMPD3 NRP1

2.89e-0416036334b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.94e-04161363787f91f906756ef570c0d02936c3cdfafb3f7454
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.94e-041613633db97af49520dc8cbafb4454d8afd9d588160e89
ToppCellfacs-MAT-Fat-24m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.94e-0416136365888250b8c1da6a8f9b5376e086a3769a1cbbd8
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

2.94e-04161363f1d258c81bcf0f3c52bd20aa58faa9a5fd888168
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA7 MMP17 NRP1

3.00e-0416236358da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA7 MMP17 NRP1

3.00e-041623634d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 ADAM8 MAPK8IP3

3.05e-04163363abec4389cd88252449f110fe95416d67424b403a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 C1QTNF2 NRP1

3.05e-04163363bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

C1QB GRIP2 NRP1

3.05e-04163363240d9f0ea45e8b2c7173e7674fd740555810f9e7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 C1QTNF2 NRP1

3.05e-041633638e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

C1QB MMP17 NRP1

3.11e-04164363057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCell390C-Lymphocytic-ILC|390C / Donor, Lineage, Cell class and subclass (all cells)

COL24A1 SMPD3 LCK

3.11e-04164363b0fc63b72162b5cc4d1e0a271a12f3d3ab29398f
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIP2 MMP9 ADAM8

3.11e-041643638e6dbddacd56a07769163813e3ebfad13302bb62
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK MMP9 ADAM8

3.16e-04165363eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 MIDEAS ADAM8

3.16e-0416536384eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

BHLHE41 COL24A1 MOXD1

3.16e-04165363a379fa981db51bec01adea7b1e55e133e15ec383
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QB MMP9 ADAM8

3.16e-041653638a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 MIDEAS ADAM8

3.16e-04165363af59a095ecc6758abc13d763c00e44447c488167
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIP2 MMP9 ADAM8

3.16e-041653634fe7c3c9370a556cf4e308a2e723b4b907a6cc25
ToppCellInfluenza_Severe-pDC|World / Disease group and Cell class

COL24A1 SMPD3 NRP1

3.22e-04166363bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A

HLCS LSS MTHFR RYR2 RECQL5 MAPK8IP3

5.58e-071943665056_UP
DrugPhenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A

BHLHE41 LSS ITGA7 MMP17 MTHFR MAPK8IP3

6.28e-071983662312_UP
DrugCGX 0596987; Down 200; 20uM; PC3; HT_HG-U133A

LSS MTHFR RECQL5 MAPK8IP3 NRP1

1.40e-051973656369_DN
DrugDeoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A

HLCS LSS ADAM8 RECQL5 MAPK8IP3

1.40e-051973656758_DN
DrugSpiramycin [8025-81-8]; Down 200; 4.8uM; HL60; HT_HG-U133A

BHLHE41 LSS MMP9 RYR2 RECQL5

1.40e-051973652558_DN
DrugTridihexethyl chloride; Up 200; 11.4uM; PC3; HT_HG-U133A

LSS MMP9 ITGA7 RYR2 SCN4A

1.43e-051983655067_UP
DrugMoricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; HL60; HT_HG-U133A

BHLHE41 LSS ITGA7 ADAM8 NRP1

1.43e-051983652959_DN
DrugKetoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A

HLCS C1QB LSS BSN MAPK8IP3

1.43e-051983652316_UP
DrugIsopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; MCF7; HT_HG-U133A

HLCS LSS ADAM8 MTHFR MAPK8IP3

1.43e-051983657233_UP
Drugfluorophenylalanine

LCK ADAM8

6.77e-058362CID000009465
DrugAC1L1DD6

COL24A1 SMPD3 MMP9 MMP17

1.79e-04179364CID000002299
DrugSalbutamol [18559-94-9]; Up 200; 16.8uM; PC3; HT_HG-U133A

HLCS RYR2 RECQL5 SCN4A

2.11e-041873643677_UP
DrugBeclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; PC3; HT_HG-U133A

HLCS LSS RYR2 MAPK8IP3

2.29e-041913644580_UP
DrugAld1.1-H_000455; Up 200; 10uM; MCF7; HT_HG-U133A

LCK ADAM8 RYR2 MAPK8IP3

2.29e-041913647542_UP
DrugICI 182,780; Down 200; 0.01uM; PC3; HT_HG-U133A

HLCS LSS RECQL5 MAPK8IP3

2.34e-041923644462_DN
Drug15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

HLCS LSS MOXD1 MAPK8IP3

2.34e-041923647526_UP
DrugNimodipine [66085-59-4]; Down 200; 9.6uM; HL60; HT_HG-U133A

BHLHE41 HLCS ITGA7 RYR2

2.38e-041933643103_DN
DrugPenbutolol sulfate [38363-32-5]; Up 200; 5.8uM; MCF7; HT_HG-U133A

BHLHE41 ITGA7 ADAM8 MAPK8IP3

2.38e-041933643534_UP
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

HLCS LSS RECQL5 MAPK8IP3

2.38e-041933644343_DN
DrugCP-690334-01 [459212-38-5]; Up 200; 10uM; MCF7; HT_HG-U133A

HLCS C1QB LSS RECQL5

2.43e-041943643906_UP
DrugIndoprofen [31842-01-0]; Down 200; 14.2uM; PC3; HT_HG-U133A

HLCS LSS ST6GALNAC2 RYR2

2.43e-041943644249_DN
DrugRacecadotril [81110-73-8]; Down 200; 10.4uM; PC3; HT_HG-U133A

HLCS MOXD1 ST6GALNAC2 MAPK8IP3

2.43e-041943645755_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

CDC42EP4 ADAM8 MTHFR MAPK8IP3

2.43e-041943642672_DN
Drugpioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A

BHLHE41 MMP17 RYR2 RECQL5

2.43e-041943647523_UP
DrugTolbutamide [64-77-7]; Up 200; 14.8uM; PC3; HT_HG-U133A

LCK ITGA7 RYR2 MAPK8IP3

2.48e-041953643804_UP
DrugDihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; PC3; HT_HG-U133A

HLCS LSS MOXD1 RECQL5

2.48e-041953644502_DN
Drug6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; PC3; HT_HG-U133A

HLCS LSS MTHFR RYR2

2.48e-041953644250_DN
DrugPhenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A

HLCS C1QB MAPK8IP3 NRP1

2.48e-041953644747_UP
DrugEnilconazole [35554-44-0]; Up 200; 13.4uM; PC3; HT_HG-U133A

ITGA7 MTHFR RECQL5 MAPK8IP3

2.48e-041953645113_UP
DrugHydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A

LSS ADAM8 RYR2 RECQL5

2.48e-041953642283_DN
DrugPhenacetin [62-44-2]; Down 200; 22.4uM; PC3; HT_HG-U133A

HLCS MTHFR RECQL5 MAPK8IP3

2.48e-041953643992_DN
DrugCimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HT_HG-U133A

LSS MTHFR SCN4A MAPK8IP3

2.48e-041953644063_UP
Drugchloroprene

MOXD1 MAPK8IP3

2.52e-0415362CID000031369
DrugPD173956

MOXD1 LCK

2.52e-0415362CID005330524
DrugGuanethidine sulfate [60-02-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

MOXD1 MMP17 RYR2 RECQL5

2.53e-041963643171_UP
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; PC3; HT_HG-U133A

MOXD1 CDC42EP4 ADAM8 RECQL5

2.53e-041963646335_DN
DrugFuraltadone hydrochloride [3759-92-0]; Down 200; 11uM; HL60; HT_HG-U133A

LSS RYR2 RECQL5 MAPK8IP3

2.58e-041973642554_DN
Drughaloperidol; Down 200; 10uM; HL60; HT_HG-U133A

HLCS MMP9 MTHFR RECQL5

2.58e-041973642704_DN
DrugNisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; HL60; HT_HG-U133A

HLCS MOXD1 RECQL5 NRP1

2.58e-041973643117_UP
DrugDihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A

ITGA7 ADAM8 MTHFR MAPK8IP3

2.58e-041973644152_UP
Druggenistein; Down 200; 10uM; HL60; HT_HG-U133A

LSS MMP9 ITGA7 RECQL5

2.58e-041973642695_DN
DrugEpiandrosterone [481-29-8]; Up 200; 13.8uM; HL60; HT_HG-U133A

MTHFR ST6GALNAC2 RECQL5 MAPK8IP3

2.58e-041973642444_UP
DrugRicinine [524-40-3]; Up 200; 24.4uM; MCF7; HT_HG-U133A

HLCS C1QB MTHFR RYR2

2.58e-041973646067_UP
DrugDebrisoquin sulfate [581-88-4]; Up 200; 9uM; PC3; HT_HG-U133A

HLCS LSS ADAM8 RECQL5

2.58e-041973646688_UP
DrugChlormezanone [80-77-3]; Up 200; 14.6uM; PC3; HT_HG-U133A

MMP9 BSN RECQL5 MAPK8IP3

2.58e-041973644636_UP
DrugPropidium iodide [25535-16-4]; Up 200; 6uM; PC3; HT_HG-U133A

HLCS LSS ADAM8 MMP17

2.58e-041973645803_UP
Drugfluphenazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

LSS MTHFR MAPK8IP3 NRP1

2.63e-041983641178_UP
DrugFlufenamic acid [530-78-9]; Up 200; 14.2uM; PC3; HT_HG-U133A

MMP9 MTHFR ST6GALNAC2 RYR2

2.63e-041983645059_UP
DrugOrphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A

BHLHE41 RECQL5 SCN4A MAPK8IP3

2.63e-041983643883_UP
DrugDeferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A

HLCS LSS RYR2 RECQL5

2.63e-041983643417_UP
DrugAmoxapine [14028-44-5]; Up 200; 12.8uM; HL60; HG-U133A

LSS MOXD1 RECQL5 MAPK8IP3

2.63e-041983642013_UP
DrugFoliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A

MTHFR RYR2 RECQL5 MAPK8IP3

2.63e-041983644761_UP
DrugSuprofen [40828-46-4]; Down 200; 15.4uM; PC3; HT_HG-U133A

MTHFR RYR2 RECQL5 MAPK8IP3

2.63e-041983644005_DN
DrugMafenide hydrochloride [138-37-4]; Up 200; 18uM; PC3; HT_HG-U133A

LSS MMP9 ST6GALNAC2 RYR2

2.68e-041993645079_UP
DrugProtoveratrine A [143-57-7]; Up 200; 5uM; HL60; HT_HG-U133A

HLCS RYR2 RECQL5 MAPK8IP3

2.68e-041993642144_UP
Drug0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A

ADAM8 MMP17 ST6GALNAC2 RYR2

2.68e-041993643774_UP
DrugHeliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A

LSS MOXD1 ADAM8 MAPK8IP3

2.68e-041993643615_UP
DrugAntipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; PC3; HT_HG-U133A

MMP9 ADAM8 MTHFR NRP1

2.73e-042003644095_DN
DrugFenbendazole [43210-67-9]; Down 200; 13.4uM; PC3; HT_HG-U133A

TUBB6 ADAM8 RECQL5 NRP1

2.73e-042003644542_DN
Drug1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one

FKBP9 BHLHE41 TUBB6 SMPD3 ITGA7

2.85e-04373365ctd:C540355
DiseaseDown syndrome (is_implicated_in)

MMP9 MTHFR

2.04e-056352DOID:14250 (is_implicated_in)
Diseaseangle-closure glaucoma (is_implicated_in)

MMP9 MTHFR

2.86e-057352DOID:13550 (is_implicated_in)
Diseaseepilepsy (implicated_via_orthology)

BSN ITGA7 SBF2 SCN4A

4.11e-05163354DOID:1826 (implicated_via_orthology)
DiseaseLiver diseases

MMP9 MTHFR NRP1

8.62e-0572353C0023895
DiseaseLiver Dysfunction

MMP9 MTHFR NRP1

8.62e-0572353C0086565
Diseasepulmonary emphysema (is_marker_for)

SMPD3 MMP9

1.23e-0414352DOID:9675 (is_marker_for)
Diseaseocular hypertension (biomarker_via_orthology)

C1QB MMP9

1.84e-0417352DOID:9282 (biomarker_via_orthology)
DiseaseAlopecia

LSS MTHFR

2.31e-0419352C0002170
Diseasesystemic scleroderma (is_implicated_in)

MMP9 HNRNPL

3.71e-0424352DOID:418 (is_implicated_in)
Diseasecataract (is_implicated_in)

LSS MTHFR

4.36e-0426352DOID:83 (is_implicated_in)
Diseasechronic obstructive pulmonary disease (biomarker_via_orthology)

SMPD3 MMP9

5.07e-0428352DOID:3083 (biomarker_via_orthology)
DiseaseIGA Glomerulonephritis

C1QB ST6GALNAC2

7.49e-0434352C0017661
DiseaseColonic Neoplasms

MMP9 ITGA7 MTHFR

7.77e-04152353C0009375
DiseaseMalignant tumor of colon

MMP9 ITGA7 MTHFR

8.85e-04159353C0007102
DiseaseMoyamoya disease

MTHFR SBF2

1.04e-0340352MONDO_0016820
Diseasecongestive heart failure (implicated_via_orthology)

MMP9 RYR2

1.09e-0341352DOID:6000 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GYGGEAEARPDREKG

BHLHE41

241

Q9C0J9
EPLDEGGEGGRHAVY

ADAM8

141

P78325
HEGHLDDGGYTPDLK

RBMY1A1

126

P0DJD3
HEGHLDDGGYTPDLK

RBMY1C

126

P0DJD4
HEGHLDDGGYTPDLK

RBMY1F

126

Q15415
GVAEHGDGYPFDGKD

MMP9

171

P14780
GDGYPFDGKDGLLAH

MMP9

176

P14780
GYPKGHPEAGSFEAD

MTHFR

196

P42898
YIFESKGDGGGGEHP

LRP11

431

Q86VZ4
EGARPGGIIHVYGDD

MAPK8IP3

1196

Q9UPT6
VGYDHEKPGSGEGLG

SBF2

11

Q86WG5
SEEDSYDPRGKGGHL

BSN

3291

Q9UPA5
AGDSDRGGGPVEHYH

HLCS

86

P50747
GFPGKDGQDGHDGDR

C1QTNF2

61

Q9BXJ5
DGGRHGDGYRHPESS

DDX42

836

Q86XP3
PDGGFATYETKRGGH

LSS

496

P48449
SYEPSHDGDLGFEKG

LCK

71

P06239
RPCSYGKGGGDAHDE

EPHA10

591

Q5JZY3
EYKGDGGRHPGDEAA

SMPD3

211

Q9NY59
PGYEGEGEGDKNISR

NRP1

831

O14786
FLAYGEDGDGKDIPG

FKBP9

226

O95302
PDKGKGDGRYGSNDD

CD99L2

161

Q8TCZ2
DPEEGEGGYHGDEGA

CDC42EP4

231

Q9H3Q1
GLAGDHGEFGEKGDP

C1QB

66

P02746
VKEEQYLGHEGPGGA

MIDEAS

41

Q6PJG2
GGGGENYDDPHKTPA

HNRNPL

86

P14866
ADLAHLDDGPYEAGG

ITGA7

236

Q13683
GEADDGPYSKGGKDA

GRIP2

11

Q9C0E4
LEFDGGSRGKGEHFP

RYR2

2941

Q92736
LEGGEADGDPAHGKD

SCN4A

491

P35499
KADHNDGYPFDGPGG

MMP17

191

Q9ULZ9
EGLDKGDRPHAYFGP

ST6GALNAC2

251

Q9UJ37
GERGEPGAEGYKGHV

COL24A1

1216

Q17RW2
PEKYTGEEDGAGGHS

RECQL5

801

O94762
DAGEAGPKYHDSNRG

MOXD1

151

Q6UVY6
DEHGIDPAGGYVGDS

TUBB6

26

Q9BUF5
AEPYAADEGSGEGHK

USP47

1036

Q96K76
AKSLEGGGAGPVDYH

XXYLT1

86

Q8NBI6