Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionspectrin binding

GBP1 GBP2 GBP3 USH1C SPTBN5

1.89e-06341225GO:0030507
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RANBP2 RGPD8 RGPD3

5.96e-06201224GO:0061665
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 IPO5 RANBP2 RGPD8 GBP1 GBP2 GBP3 RGPD3 FGD6 ARHGEF6 RGPD5 SOS1 SOS2

1.38e-0550712213GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 IPO5 RANBP2 RGPD8 GBP1 GBP2 GBP3 RGPD3 FGD6 ARHGEF6 RGPD5 SOS1 SOS2

1.38e-0550712213GO:0030695
GeneOntologyMolecularFunctionG protein activity

GBP1 GBP2 GBP3 RAB2B RAB2A

3.02e-05591225GO:0003925
GeneOntologyMolecularFunctionmyosin tail binding

USH1C SPTBN5

3.70e-0521222GO:0032029
GeneOntologyMolecularFunctionGDP phosphatase activity

GBP1 GBP2 GBP3

4.70e-05121223GO:0004382
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RANBP2 RGPD8 RGPD3

6.72e-05361224GO:0019789
GeneOntologyMolecularFunctionnucleoside diphosphate phosphatase activity

GBP1 GBP2 GBP3

2.35e-04201223GO:0017110
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RANBP2 RGPD8 RGPD3

2.46e-04501224GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RANBP2 RGPD8 RGPD3

3.08e-04531224GO:0016859
GeneOntologyMolecularFunctionHsp90 protein binding

GBP1 GBP2 GBP3 CHORDC1

3.56e-04551224GO:0051879
GeneOntologyMolecularFunctioncytoskeletal protein binding

CTNNAL1 MAP7D3 ATCAY CAPN6 GBP1 GBP2 GAS7 GBP3 PSMD10 LCP1 USH1C HDGFL3 CLIP4 SPTBN5 STAU2 USH2A MYBPC2

3.73e-04109912217GO:0008092
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 IPO5 RANBP2 RGPD8 RGPD3 RGPD5

1.24e-09201206GO:0006607
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

1.34e-0791204GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

2.23e-07101204GO:1903301
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

7.48e-07131204GO:0033131
GeneOntologyBiologicalProcesspositive regulation of AIM2 inflammasome complex assembly

GBP1 GBP2 GBP3

7.65e-0741203GO:0140973
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

1.04e-06141204GO:1903299
GeneOntologyBiologicalProcessregulation of AIM2 inflammasome complex assembly

GBP1 GBP2 GBP3

3.79e-0661203GO:0140971
GeneOntologyBiologicalProcessAIM2 inflammasome complex assembly

GBP1 GBP2 GBP3

1.05e-0581203GO:0140970
GeneOntologyBiologicalProcesscytolysis in another organism

GBP1 GBP2 GBP3

1.57e-0591203GO:0051715
GeneOntologyBiologicalProcesspositive regulation of pyroptotic inflammatory response

GBP1 GBP2 GBP3

1.57e-0591203GO:0140639
GeneOntologyBiologicalProcesscytolysis

GBP1 GBP2 GBP3

4.07e-05121203GO:0019835
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RANBP2 RGPD8 RGPD3

6.90e-05381204GO:0000413
GeneOntologyBiologicalProcessfructose 6-phosphate metabolic process

GPI PFKL TALDO1

1.02e-04161203GO:0006002
GeneOntologyBiologicalProcesspyroptotic inflammatory response

GSDMB GBP1 GBP2 GBP3

1.03e-04421204GO:0070269
GeneOntologyBiologicalProcessadhesion of symbiont to host

GBP1 GBP2 GBP3

2.04e-04201203GO:0044406
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RANBP2 RGPD8 RGPD3

2.75e-04541204GO:0018208
GeneOntologyBiologicalProcessRNA localization

THOC1 RGPD4 RANBP2 RGPD8 RFTN1 RGPD3 STAU2

2.82e-042171207GO:0006403
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RANBP2 RGPD8 RGPD3

7.10e-0881204GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RANBP2 RGPD8 RGPD3

2.11e-07101204GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RANBP2 RGPD8 RGPD3

9.89e-07141204GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RANBP2 RGPD8 RGPD3

2.97e-06181204GO:0044615
GeneOntologyCellularComponenthost cell part

GBP1 GBP2 GBP3

3.64e-0661203GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP1 GBP2 GBP3

3.64e-0661203GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP1 GBP2 GBP3

3.64e-0661203GO:0033655
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP1 GBP2 GBP3

3.64e-0661203GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP1 GBP2 GBP3

3.64e-0661203GO:0020005
GeneOntologyCellularComponenthost intracellular region

GBP1 GBP2 GBP3

3.64e-0661203GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP1 GBP2 GBP3

3.64e-0661203GO:0030430
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RANBP2 RGPD8 RGPD3

4.66e-06201204GO:0042405
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RANBP2 RGPD8 RGPD3

5.73e-06211204GO:0106068
GeneOntologyCellularComponentsymbiont cell surface

GBP1 GBP2 GBP3

1.01e-0581203GO:0106139
GeneOntologyCellularComponentother organism part

GBP1 GBP2 GBP3

1.51e-0591203GO:0044217
GeneOntologyCellularComponentnuclear pore

RGPD4 IPO5 RANBP2 RGPD8 RGPD3 RGPD5

2.56e-051011206GO:0005643
GeneOntologyCellularComponenthost cellular component

GBP1 GBP2 GBP3

7.98e-05151203GO:0018995
GeneOntologyCellularComponentstereocilia ankle link

USH1C USH2A

4.83e-0461202GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

USH1C USH2A

4.83e-0461202GO:0002142
GeneOntologyCellularComponentstereocilium

USH1C FCHSD2 STRC USH2A

6.70e-04691204GO:0032420
GeneOntologyCellularComponentstereocilia coupling link

USH1C USH2A

8.95e-0481202GO:0002139
GeneOntologyCellularComponentnuclear membrane

RGPD4 IPO5 RANBP2 RGPD8 LEMD2 RGPD3 STAU2 CEP131

9.25e-043491208GO:0031965
GeneOntologyCellularComponentperinuclear region of cytoplasm

ANKRD13D RGPD4 RANBP2 RGPD8 ATCAY CAPN6 GBP1 GBP2 GBP3 LCP1 YWHAB TF RGPD3 RAB2A

9.41e-0493412014GO:0048471
GeneOntologyCellularComponentstereocilium bundle

USH1C FCHSD2 STRC USH2A

1.11e-03791204GO:0032421
GeneOntologyCellularComponentinclusion body

RGPD4 RANBP2 RGPD8 RGPD3

1.80e-03901204GO:0016234
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RANBP2 RGPD8 RGPD3

2.76e-0616904MP:0003701
MousePhenoabnormal morula morphology

RGPD4 RANBP2 RGPD8 RGPD3

2.16e-0526904MP:0012058
MousePhenodecreased tumor latency

RGPD4 RANBP2 RGPD8 RGPD3

3.87e-0530904MP:0010308
MousePhenoincreased susceptibility to parasitic infection induced morbidity/mortality

GBP1 GBP2 GBP3

4.10e-0511903MP:0010750
MousePhenofailure of blastocyst formation

RGPD4 RANBP2 RGPD8 RGPD3

4.43e-0531904MP:0012129
MousePhenoabnormal tumor latency

RGPD4 RANBP2 RGPD8 RGPD3

6.43e-0534904MP:0010307
MousePhenofailure of blastocyst to hatch from the zona pellucida

THOC1 RGPD4 RANBP2 RGPD8 ZC3H4 RGPD3

6.46e-05107906MP:0003694
MousePhenoabnormal blastocyst hatching

THOC1 RGPD4 RANBP2 RGPD8 ZC3H4 RGPD3

8.76e-05113906MP:0003693
MousePhenoabnormal blastocyst formation

RGPD4 RANBP2 RGPD8 RGPD3

1.11e-0439904MP:0012128
MousePhenoabnormal rod electrophysiology

RGPD4 RANBP2 RELN RGPD8 KCNV2 RGPD3

1.17e-04119906MP:0004021
MousePhenoincreased heart rate variability

GBP1 GBP2 GBP3 AKAP10

1.36e-0441904MP:0003928
MousePhenoincreased incidence of tumors by chemical induction

RGPD4 NLRP12 RANBP2 RGPD8 CHORDC1 RGPD3

2.94e-04141906MP:0004499
DomainRan_BP1

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

7.07e-09121185PF00638
DomainRANBD1

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

7.07e-09121185PS50196
DomainRanBD

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

1.14e-08131185SM00160
DomainRan_bind_dom

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

1.14e-08131185IPR000156
DomainGrip

RGPD4 RGPD8 RGPD3 RGPD5

4.83e-07111184SM00755
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD5

4.83e-07111184PF01465
DomainGRIP_dom

RGPD4 RGPD8 RGPD3 RGPD5

7.21e-07121184IPR000237
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD5

7.21e-07121184PS50913
DomainRab_bind

RGPD4 RGPD8 RGPD3

8.45e-0671183PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD8 RGPD3

8.45e-0671183IPR032023
DomainGBP_C

GBP1 GBP2 GBP3

2.86e-05101183PF02841
Domain-

RGPD4 RGPD8 RGPD3

2.86e-051011831.10.220.60
DomainG_GB1_RHD3_dom

GBP1 GBP2 GBP3

3.91e-05111183IPR030386
DomainGuanylate-bd_N

GBP1 GBP2 GBP3

3.91e-05111183IPR015894
DomainGuanylate-bd_C

GBP1 GBP2 GBP3

3.91e-05111183IPR003191
DomainGBP

GBP1 GBP2 GBP3

3.91e-05111183PF02263
DomainG_GB1_RHD3

GBP1 GBP2 GBP3

3.91e-05111183PS51715
DomainPH_dom-like

RGPD4 RANBP2 RGPD8 SPTBN5 RGPD3 FGD6 ARHGEF6 RGPD5 SOS1 SOS2

3.73e-0442611810IPR011993
Domain-

RGPD4 RANBP2 RGPD8 SPTBN5 RGPD3 FGD6 ARHGEF6 SOS1 SOS2

8.47e-0439111892.30.29.30
DomainRhoGEF

FGD6 ARHGEF6 SOS1 SOS2

9.03e-04681184SM00325
DomainRhoGEF

FGD6 ARHGEF6 SOS1 SOS2

1.01e-03701184PF00621
DomainDH_2

FGD6 ARHGEF6 SOS1 SOS2

1.01e-03701184PS50010
Domain-

FGD6 ARHGEF6 SOS1 SOS2

1.06e-037111841.20.900.10
DomainDH-domain

FGD6 ARHGEF6 SOS1 SOS2

1.06e-03711184IPR000219
DomainVIT

PARP4 VWA5A

1.08e-0381182PF08487
DomainVIT

PARP4 VWA5A

1.08e-0381182SM00609
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RANBP2 RGPD8 RGPD3

4.06e-0618884MM1549
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 GPI RANBP2 RGPD8 PFKL RGPD3

1.19e-0582886MM15394
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RANBP2 RGPD8 TNRC6B RGPD3

1.30e-0549885MM14837
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RANBP2 RGPD8 RGPD3

1.09e-0440884MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RANBP2 RGPD8 RGPD3

1.20e-0441884MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RANBP2 RGPD8 RGPD3

1.32e-0442884MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RANBP2 RGPD8 RGPD3

1.45e-0443884MM14609
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

THOC1 RGPD4 RANBP2 RGPD8 RGPD3

1.98e-0486885MM15413
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RANBP2 RGPD8 RGPD3

2.06e-0447884MM14939
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RANBP2 RGPD8 RGPD3

2.62e-0450884MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RANBP2 RGPD8 RGPD3

2.83e-0451884MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RANBP2 RGPD8 RGPD3

3.79e-0455884MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RANBP2 RGPD8 RGPD3

4.65e-0458884MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RANBP2 RGPD8 RGPD3

4.65e-0458884MM14736
PathwayWP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA

PIK3R3 PRCC SOS1 SOS2

4.97e-0459884M39750
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122421205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122418949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122425187515
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-09712249037092
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-09712248603673
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD8 RGPD3 RGPD5

5.00e-097122415710750
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122426632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122424403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122423818861
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122411353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122430944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122438838144
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122423536549
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-09712247559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122417372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122438657106
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122412191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122422821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RANBP2 RGPD8 RGPD3

5.00e-097122420682751
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RANBP2 RGPD8 RGPD3

9.98e-098122422262462
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RANBP2 RGPD8 RGPD3

9.98e-098122421670213
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RANBP2 RGPD8 RGPD3

9.98e-098122428745977
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RANBP2 RGPD8 RGPD3

9.98e-098122427412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RANBP2 RGPD8 RGPD3

9.98e-098122421310149
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RANBP2 RGPD8 RGPD3

1.79e-089122418394993
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RANBP2 RGPD8 RGPD3

1.79e-089122411553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RANBP2 RGPD8 RGPD3

1.79e-089122410601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RANBP2 RGPD8 RGPD3

1.79e-08912249733766
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RANBP2 RGPD8 RGPD3

1.79e-089122428100513
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RANBP2 RGPD8 RGPD3

1.79e-089122428877029
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RANBP2 RGPD8 RGPD3

1.79e-089122417887960
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RANBP2 RGPD8 RGPD3

2.98e-081012248857542
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RANBP2 RGPD8 RGPD3

2.98e-0810122427160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RANBP2 RGPD8 RGPD3

2.98e-0810122416332688
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RANBP2 RGPD8 RGPD3

2.98e-0810122421859863
Pubmed

Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa.

GBP1 GBP2 GBP3

4.21e-083122330062052
Pubmed

Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

GBP1 GBP2 GBP3

4.21e-083122326416908
Pubmed

Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.

GBP1 GBP2 GBP3

4.21e-083122332354743
Pubmed

GTPase properties of the interferon-induced human guanylate-binding protein 2.

GBP1 GBP2 GBP3

4.21e-08312238706832
Pubmed

Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection.

GBP1 GBP2 GBP3

4.21e-083122332620042
Pubmed

[Guanylate-binding protein 2 regulates the maturation of mouse dendritic cells induced by β-glucan].

GBP1 GBP2 GBP3

4.21e-083122329089068
Pubmed

Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.

GBP1 GBP2 GBP3

4.21e-083122323248289
Pubmed

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

GBP1 GBP2 GBP3

4.21e-08312231715024
Pubmed

Two families of GTPases dominate the complex cellular response to IFN-gamma.

GBP1 GBP2 GBP3

4.21e-08312239862701
Pubmed

The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation.

GBP1 GBP2 GBP3

4.21e-083122311726669
Pubmed

GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.

GBP1 GBP2 GBP3

4.21e-083122338636926
Pubmed

Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2.

GBP1 GBP2 GBP3

4.21e-083122336639389
Pubmed

The interferon-induced GTPase, mGBP-2, confers resistance to paclitaxel-induced cytotoxicity without inhibiting multinucleation.

GBP1 GBP2 GBP3

4.21e-083122316914101
Pubmed

The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.

GBP1 GBP2 GBP3

4.21e-083122322730319
Pubmed

Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain.

GBP1 GBP2 GBP3

4.21e-083122315717119
Pubmed

Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target.

GBP1 GBP2 GBP3

4.21e-083122335383115
Pubmed

Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2.

GBP1 GBP2 GBP3

4.21e-083122320950129
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RANBP2 RGPD8 RGPD3

4.67e-0811122435771867
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RANBP2 RGPD8 RGPD3

4.67e-0811122417069463
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RANBP2 RGPD8 RGPD3

4.67e-0811122434110283
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RANBP2 RGPD8 RGPD3

1.01e-0713122431427429
Pubmed

Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon.

GBP1 GBP2 GBP3

1.68e-07412237823961
Pubmed

Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis.

GBP1 GBP2 GBP3

1.68e-074122336609599
Pubmed

Genomic organization and chromosomal localization of a new member of the murine interferon-induced guanylate-binding protein family.

GBP1 GBP2 GBP3

1.68e-074122310386861
Pubmed

Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.

GBP1 GBP2 GBP3

1.68e-074122338404575
Pubmed

Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.

RANBP2 RGPD8 RGPD5

1.68e-07412239480752
Pubmed

cDNA for the beta 1 subunit of guanyl nucleotide-binding regulatory proteins from mouse adrenal glands.

GBP1 GBP2 GBP3

1.68e-07412238917111
Pubmed

The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site.

GBP1 GBP2 GBP3

1.68e-074122339337476
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RANBP2 RGPD8 RGPD3

1.91e-0715122414697343
Pubmed

TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.

GBP1 GBP2 GBP3

4.19e-075122330858199
Pubmed

Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro.

GBP1 GBP2 GBP3

4.19e-075122312396730
Pubmed

Unique features of different members of the human guanylate-binding protein family.

GBP1 GBP2 GBP3

4.19e-075122317266443
Pubmed

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

GBP1 GBP2 GBP3

4.19e-075122321151871
Pubmed

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.

GBP1 GBP2 GBP3

4.19e-075122331964735
Pubmed

Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages.

GBP1 GBP2 GBP3

4.19e-07512239858320
Pubmed

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.

GBP1 GBP2 GBP3

8.36e-076122317293456
Pubmed

Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.

GBP1 GBP2 GBP3

8.36e-076122321757726
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RANBP2 RGPD8 RGPD3

1.00e-0622122427717094
Pubmed

The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase.

GBP1 GBP2 GBP3

1.46e-067122320505078
Pubmed

TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis.

GBP1 GBP2 GBP3

1.46e-067122330587103
Pubmed

The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein.

GBP1 GBP2 GBP3

1.46e-067122321502320
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

PIK3R3 YWHAB HDGFL3 FGD6 SOS1 SOS2

1.78e-06103122621706016
Pubmed

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.

GBP1 GBP2 GBP3

2.33e-068122316689661
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 RANBP2 RGPD8 ATG2B TNRC6B ANAPC1 RGPD3 ZKSCAN3 XRN1 CEP131

2.35e-064181221034709266
Pubmed

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.

GBP1 GBP2 GBP3

3.48e-069122324739961
Pubmed

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins.

GBP1 GBP2 GBP3

3.48e-069122333479228
Pubmed

Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.

GBP1 GBP2 GBP3

4.96e-0610122328334111
Pubmed

Global landscape of HIV-human protein complexes.

SEL1L DCAF1 RANBP2 CHORDC1 YWHAB NDUFS8 PARP4 PSIP1 ANAPC1 PLOD1

5.17e-064571221022190034
Pubmed

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

GBP1 GBP2 GBP3

6.81e-0611122324715728
Pubmed

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

GBP1 GBP2 GBP3

6.81e-0611122327693356
Pubmed

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

GBP1 GBP2 GBP3

6.81e-0611122318025219
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 RANBP2 MIA3 UBAP2 RGPD8 TNRC6B FYCO1 YWHAB ANAPC1 ZC3H4 RGPD3 DCHS1 CEP131 RAB2A

7.60e-069631221428671696
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DCAF1 IPO5 PARP4 LRRC31 ANAPC1 ZC3H4 XRN1

7.65e-06202122733005030
Pubmed

Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.

GBP1 GBP2 GBP3

9.05e-0612122335906252
Pubmed

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.

GBP1 GBP2 GBP3

9.05e-0612122329459437
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RANBP2 RGPD8 RGPD3

9.70e-0638122412791264
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

THOC1 RANBP2 UBAP2 MAP7D3 TNRC6B PFKL PARP4 ANAPC1 ZC3H4 STAU2 XRN1 PLOD1

9.74e-067241221236232890
Pubmed

Molecular cloning and characterization of a novel human Rab ( Rab2B) gene.

RAB2B RAB2A

1.22e-052122212376746
Pubmed

Dimerization and its role in GMP formation by human guanylate binding proteins.

GBP1 GBP2

1.22e-052122220923658
Pubmed

The interferon-inducible GBP1 gene: structure and mapping to human chromosome 1.

GBP1 GBP3

1.22e-05212227518790
Pubmed

Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivo.

TEP1 PARP4

1.22e-052122215169895
Pubmed

A homologue of the Drosophila Son of sevenless gene maps to mouse chromosome 17.

SOS1 SOS2

1.22e-05212228307589
Pubmed

Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T cells leads to PI3K pathway activation and defects in migration.

SOS1 SOS2

1.22e-052122225973715
Pubmed

Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue.

GBP1 GBP2

1.22e-052122236460216
Pubmed

Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy.

RAB2B RAB2A

1.22e-052122228063257
InteractionRGPD4 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

1.67e-07221205int:RGPD4
InteractionRGPD1 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RPS6KA6 RGPD5

4.46e-07491206int:RGPD1
InteractionRGPD2 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

5.00e-07271205int:RGPD2
InteractionRGPD8 interactions

RGPD4 RANBP2 RGPD8 PSMD10 RGPD3 RGPD5

5.23e-06741206int:RGPD8
InteractionRGPD3 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

8.65e-06471205int:RGPD3
InteractionRGPD5 interactions

RGPD4 RANBP2 RGPD8 PSMD10 RGPD3 RGPD5

2.35e-05961206int:RGPD5
InteractionGBP3 interactions

GBP1 GBP2 GBP3

2.40e-05101203int:GBP3
InteractionCEP120 interactions

MAP7D3 TNRC6B CHORDC1 ANAPC1 XRN1 CEP131

4.13e-051061206int:CEP120
InteractionCDKL5 interactions

RANBP2 UBAP2 HDGFL3 STAU2 XRN1 CEP131

5.91e-051131206int:CDKL5
InteractionCEP162 interactions

DCAF1 IPO5 MAP7D3 CAPN6 PFKL YWHAB CEP131

6.66e-051681207int:CEP162
CytobandEnsembl 112 genes in cytogenetic band chr15q15

GANC ELL3 SPTBN5 TGM7 STRC

4.82e-051471225chr15q15
Cytoband1p22.2

GBP1 GBP2 GBP3

5.71e-052812231p22.2
CytobandEnsembl 112 genes in cytogenetic band chr2q13

RANBP2 ANAPC1 RGPD5

5.34e-04591223chr2q13
Cytoband2q13

RGPD8 RGPD3 RGPD5

8.09e-046812232q13
Cytoband15q15.2

GANC TGM7

8.20e-0416122215q15.2
Cytoband2q12.3

RGPD4 RANBP2

9.28e-041712222q12.3
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

1.97e-04115845769
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD6 ARHGEF6 SOS1 SOS2

2.51e-0466844722
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RANBP2 RGPD8 RGPD3

1.54e-05331204MM477
CoexpressionMARSON_BOUND_BY_FOXP3_UNSTIMULATED

RGPD4 DCAF1 RANBP2 TTC41P RGPD8 GBP1 GBP2 GBP3 FYCO1 CHORDC1 ARID3B CD3E PRCC RGPD3 CREB3L3 RAB2A FGD6 ARHGEF6

2.06e-05127712018MM1032
CoexpressionMARZEC_IL2_SIGNALING_DN

RGPD4 PIK3R3 PDCD4 SOS1

2.20e-05361204M13276
CoexpressionGSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP

LCP1 EDA CLIP4 SUOX ZNF540 RAB2A FGD6

3.77e-051991207M7553
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RANBP2 RGPD8 RGPD3

4.49e-05431204MM3857
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

RANBP2 ZBTB38 MAP7D3 KAT6A TNRC6B GBP2 GBP3 LCP1 YWHAB PDCD4 RFTN1 CD3E PSIP1 VWA5A XRN1 AKAP10 USP15 ARHGEF6 SOS1

4.76e-05149212019M40023
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MIA3 GBP1 GBP3 CHGB LAP3 ZNF540 XRN1

4.52e-07170122707b561cd9c528bc8444c9385e1de621eee7b697e
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

NLRP12 GAS7 LCP1 PLXDC2 OTOF USP15 MARCHF1

1.21e-061971227a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

GBP1 GBP2 PARP4 PRDM8 CD3E CREB3L3 ARHGEF6

1.30e-061991227f307d4887b28cf60a591439e278fd668409cb104
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB38 KAT6A TEP1 ABCA9 FCHSD2 FGD6

7.25e-0616912265f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCellMonocytes-IFN-activated_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

GBP1 GBP2 LCP1 LAP3 STRC USH2A

9.13e-0617612266a4b403ee3e4dc4f23fbd7a154011e41fd429a9e
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IPO5 CTNNAL1 KAT6A GBP3 USP15 PLXNA2

1.18e-051841226c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GBP1 GBP2 GBP3 LAP3 CD3E XRN1

1.33e-0518812266f8946d4710f6e32c937213f99b790b098b8819c
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

GAS7 LCP1 EDA FCHSD2 PLXDC2 MARCHF1

1.37e-0518912262586f4088721c5debec86c2b211b739fd33713eb
ToppCellSevere-Treg|World / Disease group and Cell class

ZBTB38 GBP2 YWHAB RAD51AP2 SUOX DNAH8

1.45e-0519112260a80b8c317e8da4d4722cfd13cdabc32b58021eb
ToppCellILEUM-non-inflamed-(1)_Tregs|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ZBTB38 GBP2 YWHAB CD3E USP15 DNAH8

1.45e-051911226e065d16a1f88c91dec576d248a318534ceab1cb2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NLRP12 GAS7 LCP1 PLXDC2 USP15 MARCHF1

1.45e-05191122647a2afc4102199b4bc76bd01b2967c8016186462
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZAN LIPK STAR OTOF USH2A DNAH8

1.54e-051931226315840bc48899f3a36d57b19197509de19716e3d
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

GAS7 LCP1 PLXDC2 USP15 TALDO1 MARCHF1

1.63e-0519512260fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZBTB38 CHORDC1 LCP1 CD3E ZNF540 XRN1

1.68e-051961226ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

GBP1 GBP2 LAP3 OTOF XRN1 USP15

1.78e-051981226ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

GBP1 GBP2 GBP3 LAP3 XRN1 USP15

1.78e-0519812264b078714c49e7befb7b113d72485e712236d35fa
ToppCellImmune-monocyte|World / Lineage, Cell type, age group and donor

ANKRD13D NLRP12 GAS7 LCP1 PLXDC2 MARCHF1

1.78e-051981226d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCellEndothelial-Endothelial-F|Endothelial / shred on cell class and cell subclass (v4)

GBP2 GBP3 LCP1 LAP3 DNAH8

2.17e-0512212252cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Reln_(Medial_entorrhinal_cortexm,_Reln+/Cbln1+)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

LIPK USH1C STRC MYBPC2

2.38e-056112245e855b5462f42b7a1d0bbd518cc11072342ce0cc
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Reln_(Medial_entorrhinal_cortexm,_Reln+/Cbln1+)|Hippocampus / BrainAtlas - Mouse McCarroll V32

LIPK USH1C STRC MYBPC2

2.38e-056112242fc13475581431f82e0b5ef42e18cd29c9787666
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP7D3 TEP1 OTOF AKAP10 MAP3K19

3.41e-051341225932b7dd5781b730dcd2ffe43f6e142e3f8630f67
ToppCellsevere_COVID-19-CD8+_T_naive|severe_COVID-19 / disease group, cell group and cell class (v2)

ZNF705EP EDA PDCD4 CD3E ZNF540

7.03e-05156122547aa46cdf5af9834f4b890ac6ce5e8d548ee98db
ToppCellE18.5-Immune-Immune_Myeloid-DC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEP1 STRIP2 TALDO1 MARCHF1 ARHGEF6

7.92e-0516012259f1fec2cf565193c73cc3c8a4f0476e57478e3b8
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEP1 STRIP2 ARID3B MARCHF1 ARHGEF6

8.40e-051621225388670cf3acef17df971c0d8ae3ce14398945192
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEP1 STRIP2 ARID3B MARCHF1 ARHGEF6

8.40e-0516212259333d923225df7bfdf6b3a4c32816751315aec50
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3A UBAP2 STAR ZNF540 CEP131

8.64e-0516312251c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

PDE3A STRIP2 VWA5A DCHS1 ARHGEF6

9.16e-0516512255fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

PDE3A STRIP2 VWA5A DCHS1 ARHGEF6

9.16e-05165122593d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell390C-Lymphocytic-ILC-ILC-2|390C / Donor, Lineage, Cell class and subclass (all cells)

PDE3A UBAP2 GSDMB CD3E SOS1

9.96e-0516812252781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCell5'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LCP1 ELL3 RFTN1 SLC6A5 FGD6

1.02e-041691225a34aff9257ae9746226ee7af595c4678a4b0c896
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A GAS7 ELL3 ABCA9 RFTN1

1.08e-0417112255d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD13D GBP1 GBP2 LCP1 ZNF835

1.08e-0417112252b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD13D GBP1 GBP2 LCP1 ZNF835

1.08e-041711225dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ATG2B GBP1 EPGN ARL6 CD3E

1.11e-041721225a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NANOGNB STAR RAD51AP2 VWA5A ARHGEF6

1.14e-041731225b9dc42d629d13e63aada5ae49ba0cbb0952c5fe9
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3R3 STRIP2 FCHSD2 XRN1 DCHS1

1.17e-0417412257be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCellInt-URO-Lymphocyte-T_NK-MAIT|Int-URO / Disease, Lineage and Cell Type

ZBTB38 PDCD4 CD3E ZNF540 RGPD5

1.17e-0417412255227ed29f5f0d3e0aaa7f3cfd362f96d3e2660f7
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 PDE3A ZBTB38 ABCA9 XRN1

1.24e-041761225749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell(1)_T_regulatory|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

GBP2 CHGB CD3E USP15 DNAH8

1.27e-0417712255cda56b10df1ee8971ce8470d52062e01b703a4e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 ZBTB38 GBP2 GBP3 XRN1

1.31e-04178122501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-MAIT_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GBP2 LCP1 CD3E OTOF ARHGEF6

1.31e-041781225f52f837e948deb6a2d031325f49891bca8d375da
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GBP1 GBP2 GBP3 LAP3 XRN1

1.34e-041791225af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FYCO1 EDA CD3E ZNF540 CREB3L3

1.34e-041791225d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NLRP12 LCP1 TEP1 ZKSCAN3 MARCHF1

1.34e-04179122561dbfc1b9b0344c06a68142c181cd62993556a67
ToppCellMonocytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

NLRP12 GAS7 LCP1 USP15 MARCHF1

1.41e-041811225d8b98c3d9bef026a0a35948219027f27718ffbee
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A TEP1 ABCA9 XRN1 MARCHF1

1.45e-041821225f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

GBP1 GBP2 GBP3 XRN1 FGD6

1.49e-0418312258f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellB_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

GBP1 GBP2 GAS7 RFTN1 DNAH8

1.49e-041831225bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ELL3 ABCA9 RFTN1 DNAH8

1.53e-041841225c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell(1)_T_cells-(1)_T_regulatory|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

ZBTB38 GBP2 CHGB USP15 DNAH8

1.53e-0418412253cbf81757653652441843d85cb7ec1dcf25ca1b0
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP1 GBP2 GBP3 LCP1 XRN1

1.56e-041851225f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D175|Adult / Lineage, Cell type, age group and donor

GAS7 EDA SPTBN5 FCHSD2 MARCHF1

1.56e-041851225ab5704b96f1d368911308797d10c7c52766ab134
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCP1 ELL3 PDCD4 FCHSD2 MARCHF1

1.60e-041861225d5d990d8b6ccd8ca8fe7d0d7dedbe2359ae7b582
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3R3 EPGN PDCD4 PLXDC2 PLXNA2

1.60e-0418612252913b5fd0617d024d600ba7015ec7b1961dade83
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

RANBP2 LCP1 YWHAB RFTN1 FGD6

1.64e-041871225457eb3791a8c5458d81833e0701ac5a9bfdee2bf
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PIK3R3 GBP1 GBP2 CLIP4 CD3E

1.64e-0418712253301e0fca8c436d136c71f1a8fd59b3bb11bdd83
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GBP1 GBP3 LAP3 XRN1 MARCHF1

1.64e-04187122572e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A LCP1 ABCA9 PLXDC2 PLOD1

1.73e-0418912256dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GAS7 LCP1 RFTN1 PLXDC2 ARHGEF6

1.73e-0418912257ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

UBAP2 ATCAY PIK3R3 CHGB PRDM8

1.73e-0418912258e6b6025f5554672e26a5d19fe365acb4333789c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A LCP1 ABCA9 PLXDC2 PLOD1

1.73e-0418912253ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A LCP1 ABCA9 PLXDC2 PLOD1

1.73e-041891225875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A LCP1 ABCA9 PLXDC2 PLOD1

1.73e-04189122597ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GBP2 YWHAB CD3E USP15 DNAH8

1.77e-041901225b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

GBP1 GBP2 GBP3 LAP3 XRN1

1.81e-0419112252da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CTNNAL1 RGPD8 MAP7D3 CHGB CHORDC1

1.86e-0419212250b954a4e5857dac45d97c491af9b27cb2d1bd339
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILC2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LCP1 PRDM8 CD3E CREB3L3 ARHGEF6

1.86e-041921225017f613b1b9c0bd0842e5c1e71d3ac60dd89eadd
ToppCellCOVID-19-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

GBP1 GBP2 LAP3 OTOF XRN1

1.86e-041921225be9d5685fa03563322f147a4b38ed31e4da59487
ToppCellILEUM-inflamed-(1)_Tregs|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ZBTB38 GBP2 YWHAB CD3E USP15

1.86e-0419212251fe3417dfd1cf1758fd82c9ac13dbd88bdf0b548
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A ABCA9 PDCD4 FCHSD2 PLXDC2

1.90e-04193122506b65110db974f4ef90d3511ff34428976a52c9c
ToppCellNS-critical-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GBP1 GBP2 LAP3 XRN1 MARCHF1

1.90e-0419312250dd83b21e164147abfd511a927615c40a28781a2
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A ABCA9 PDCD4 FCHSD2 PLXDC2

1.90e-0419312259c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A ABCA9 PDCD4 FCHSD2 PLXDC2

1.90e-041931225a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell3'_v3-blood-Lymphocytic_T_CD4-Tregs|blood / Manually curated celltypes from each tissue

ZBTB38 CTNNAL1 GBP2 YWHAB CD3E

1.90e-0419312252ffe44edf2b02d11a7c10513692eb697a10f911e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GAS7 LCP1 EDA FCHSD2 PLXDC2

1.90e-041931225bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GAS7 LCP1 EDA FCHSD2 PLXDC2

1.90e-041931225374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GBP1 LAP3 OTOF XRN1 MARCHF1

1.90e-04193122522455801194bd8c73c5c397f5eac4f723429c383
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GAS7 LCP1 PLXDC2 OTOF MARCHF1

1.90e-0419312254fb020f11fd7aff06952bfeaabc79b2c7b8873f6
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A ABCA9 PDCD4 FCHSD2 PLXDC2

1.90e-041931225b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellSevere-Treg|Severe / Disease group and Cell class

ZBTB38 GBP2 YWHAB SUOX DNAH8

1.95e-0419412257d232d87262ec5f505901345da5113cabf821321
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GAS7 LCP1 PLXDC2 OTOF MARCHF1

1.95e-041941225885355ebe98e974f841cc59dce3b5228c642c5d0
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GBP1 GBP2 LAP3 XRN1 MARCHF1

1.95e-041941225e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCellAdult-Immune-monocyte-D231|Adult / Lineage, Cell type, age group and donor

ANKRD13D GAS7 LCP1 PLXDC2 MARCHF1

2.00e-041951225ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCellCOVID-19-Lymphoid-Tregs|Lymphoid / Condition, Lineage and Cell class

ZBTB38 GBP2 CHGB SUOX DNAH8

2.00e-0419512259ad844d9d5aac39d133ae8ab9c4839300f08064c
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NLRP12 GAS7 PLXDC2 TALDO1 MARCHF1

2.00e-0419512250110b976f98561ecd2e20ff6e7e3960a401bb7c2
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GBP1 GBP2 GBP3 LAP3 XRN1

2.00e-041951225b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NLRP12 GAS7 PLXDC2 TALDO1 MARCHF1

2.00e-041951225050fc59b328391d6e3ce23051764a842dcbb3144
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB38 ABCA9 PLXDC2 XRN1 MYBPC2

2.00e-0419512255c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

ANKRD13D GAS7 LCP1 PLXDC2 MARCHF1

2.05e-0419612253ef193c5180de3137daf886492e74fc574bc9767
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

NLRP12 GAS7 LCP1 PLXDC2 MARCHF1

2.05e-041961225cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEL1L CHORDC1 LCP1 PLXDC2 USP15

2.05e-0419612255fe6534af65d43eeacd4b031310242b4f706008b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GAS7 LCP1 FCHSD2 PLXDC2 MARCHF1

2.09e-0419712258af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellControl-B_memory-3|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZBTB38 LCP1 CLIP4 DNAH8 FGD6

2.09e-041971225b86385c6c1d52ef4e3d855004d77afab61556978
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GAS7 LCP1 FCHSD2 PLXDC2 MARCHF1

2.09e-041971225c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCellmild-Treg|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZBTB38 GBP1 CD3E PSIP1 USP15

2.09e-04197122539800e6e83f2d333b753d121c7aeb2912b91faa2
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

GBP1 LAP3 OTOF XRN1 USP15

2.09e-0419712255c33454b10023decd2f5ccda9229b6512659711e
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZBTB38 GBP2 SUOX USP15 DNAH8

2.09e-04197122554fb7197db3c0dc87a1114e1ab1d2bfafd564b35
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NLRP12 GAS7 LCP1 PLXDC2 MARCHF1

2.09e-0419712251eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCellCOVID-19_Moderate-Classical_Monocyte|World / disease group, cell group and cell class

GBP1 GAS7 PLXDC2 OTOF MARCHF1

2.09e-04197122516cf3939e700aef1e16159f0652ba2dfad287e7a
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells|LPS_only / Treatment groups by lineage, cell group, cell type

LCP1 LAP3 STRIP2 RFTN1 MARCHF1

2.09e-04197122559ddd8ff7dddf3747b988374e1a4d80959db803e
Diseasechronic kidney disease, Proteinuria

GAS7 PLXDC2 TALDO1

9.06e-06111143EFO_0003884, HP_0000093
DiseaseUsher syndrome (is_implicated_in)

USH1C USH2A

8.83e-0541142DOID:0050439 (is_implicated_in)
Diseaselow-density lipoprotein receptor-related protein 1, soluble measurement

NLRP12 LCP1

1.47e-0451142EFO_0801772
DiseaseETS domain-containing protein Elk-3 measurement

NLRP12 PLOD1

2.20e-0461142EFO_0801588
Diseasecytochrome c oxidase subunit 6C measurement

NLRP12 PLXDC2

2.20e-0461142EFO_0801515
DiseaseWAP four-disulfide core domain protein 3 measurement

NLRP12 PLOD1

2.20e-0461142EFO_0802220
Diseaseplastin-2 measurement

NLRP12 LCP1

2.20e-0461142EFO_0801885
Diseaseacid ceramidase measurement

NLRP12 PLOD1

2.20e-0461142EFO_0801339
Diseaselon protease homolog, mitochondrial measurement

NLRP12 PLOD1

2.20e-0461142EFO_0801771
Diseasehypothyroidism (biomarker_via_orthology)

RELN STAR OTOF PLOD1

2.67e-04801144DOID:1459 (biomarker_via_orthology)
Diseasepulmonary function measurement, forced expiratory volume

ZBTB38 ZKSCAN2 ZKSCAN3

3.97e-04371143EFO_0003892, EFO_0004314
Diseaseaspirin use measurement

MIA3 LCP1 FGD6

4.64e-04391143EFO_0007013
Diseaseserum non-albumin protein measurement

MIA3 ZBTB38 KAT6A GSDMB TF MAP3K19 SOS2

5.20e-043611147EFO_0004568
Diseasecortical surface area measurement

RELN PDE3A ZAN TNRC6B LRRIQ1 PLXDC2 SUOX STAU2 XRN1 AKAP10 FGD6 PLXNA2 SOS1 SOS2

6.92e-04134511414EFO_0010736
DiseaseBardet-Biedl syndrome (implicated_via_orthology)

ARL6 CEP131

7.95e-04111142DOID:1935 (implicated_via_orthology)
DiseaseCiliopathies

USH1C ARL6 USH2A DNAH8

8.90e-041101144C4277690
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

USH1C OTOF STRC

1.02e-03511143cv:CN043650
DiseaseMAP kinase-activated protein kinase 3 measurement

NLRP12 LCP1

1.12e-03131142EFO_0008226
Diseasecortical thickness

RELN TNRC6B GAS7 USH1C HDGFL3 LRRIQ1 PLXDC2 STAU2 AKAP10 USP15 PLXNA2 SOS2

1.26e-03111311412EFO_0004840
Diseaseangina pectoris

MIA3 LCP1 PRDM8 FGD6

1.43e-031251144EFO_0003913
Diseaseprostate carcinoma, type 2 diabetes mellitus

ZBTB38 UBAP2 TNRC6B

1.56e-03591143EFO_0001663, MONDO_0005148
DiseaseCongenital total cataract

LEMD2 FYCO1

1.71e-03161142C0266539
Diseaserheumatoid arthritis, COVID-19

GSDMB ZKSCAN2 ZKSCAN3

1.97e-03641143EFO_0000685, MONDO_0100096
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

SOS1 SOS2

2.42e-03191142C3501846
DiseaseHydrops Fetalis

TALDO1 SOS2

2.42e-03191142C0020305
Diseasecortical surface area change measurement, age at assessment

TF USP15

2.42e-03191142EFO_0008007, EFO_0021503
DiseaseNoonan syndrome-like disorder with loose anagen hair

SOS1 SOS2

2.42e-03191142C1843181
DiseaseCardio-facio-cutaneous syndrome

SOS1 SOS2

2.42e-03191142C1275081
DiseaseCostello syndrome (disorder)

SOS1 SOS2

2.42e-03191142C0587248
Diseasealpha-tocopherol measurement

USH2A SOS1

2.69e-03201142EFO_0007898
DiseaseNonsyndromic genetic hearing loss

USH1C OTOF STRC

3.22e-03761143cv:C5680182
DiseaseLEOPARD Syndrome

SOS1 SOS2

3.25e-03221142C0175704
Diseaseintraocular pressure measurement

SEL1L RELN TTC41P GAS7 EDA ANAPC1 SOS2

3.68e-035091147EFO_0004695
DiseaseNoonan Syndrome

SOS1 SOS2

3.86e-03241142C0028326

Protein segments in the cluster

PeptideGeneStartEntry
AEAEAALQKAWNQGG

USH1C

516

Q9Y6N9
QLKQNGGLAWSDDAD

ARID3B

181

Q8IVW6
GNWTVNKTEADNIEG

EPGN

36

Q6UW88
NLTLWTSENQGDEGD

YWHAB

226

P31946
LQGLTNQDLQEGEDW

ELL3

241

Q9HB65
IQAWEGEDIKNLGNV

ARHGEF6

436

Q15052
VGKENRQGWAVLQEA

ANKRD13D

66

Q6ZTN6
VDGWTDLQKQLDNRE

CATSPER3

226

Q86XQ3
KVNSQWENGANLDDP

CTAGE9

296

A4FU28
ELGEGWGHVKDQQVL

CREB3L3

41

Q68CJ9
KWVQGNTDEAQEELA

AKAP10

621

O43572
DIGIWGQLQTDGAKD

ABCA9

801

Q8IUA7
GDKWLDELDSGLQGQ

GSDMB

66

Q8TAX9
KLGGDNTQLEAAEWL

AASS

786

Q9UDR5
KGEGLQEGVDWLQDQ

ARL6

166

Q9H0F7
QWAGIELDEPEGKNN

CLIP4

311

Q8N3C7
QDNGDLLENKHGEFW

ATG2B

1071

Q96BY7
GGRAWEQGQDHDKEN

CDCA3

246

Q99618
TVWLNGKGENDNTLQ

RAD51AP2

476

Q09MP3
EQLLDCEGEDGWNKL

RANBP2

136

P49792
DGKQIKLQIWDTAGQ

RAB2A

51

P61019
DGKQIKLQIWDTAGQ

RAB2B

51

Q8WUD1
KNGQTVSGLDANWLE

RFTN1

306

Q14699
EQLLDCEGEDGWNKL

RGPD5

136

Q99666
EQLLDCEGEDGWNKL

RGPD8

136

O14715
TIDNTLDQWLQVGGD

ANAPC1

1851

Q9H1A4
AGIDEQENWHEGKEN

LAP3

106

P28838
WGQAGSLDLQIDEEQ

DCHS1

41

Q96JQ0
TLLEQWEKEHGSGQD

DCAF1

16

Q9Y4B6
GEKNSVDWGDLNLVL

KIAA0100

2131

Q14667
DWGDSIEVKNEDQIQ

METAP1D

81

Q6UB28
EGQEGAWEAQALVLK

MCCD1

86

P59942
NKDVGIWLKGEDQSE

LEMD2

331

Q8NC56
QEELSGKGQEADQLW

FYCO1

456

Q9BQS8
GVQEAGWDLDDNNDK

GABRQ

526

Q9UN88
SLEFLGNGNELEWED

ATCAY

106

Q86WG3
AGTEEIKNEINGNWI

PDCD4

31

Q53EL6
GGGQKVNDDIIVNWV

LCP1

511

P13796
QGEGNLELNWLLGKD

PLXNA2

376

O75051
EGLVEGGENIKQANW

PFKL

56

P17858
NGKVNDDVGIDWTNE

PDE3A

921

Q14432
NWGALNQSKQGESEK

DNAH8

71

Q96JB1
QENQEDLGLWEEKFG

GANC

186

Q8TET4
ELEELNLSWNSKVGG

LRRC31

171

Q6UY01
LGDVEKGDNQNDSWI

GBP1

101

P32455
LGDIEKGDNENDSWI

GBP2

101

P32456
LGDVKKGDNQNDSWI

GBP3

101

Q9H0R5
DINSFDQWGVELGKQ

GPI

506

P06744
GGNWDNISDGAKDLL

RPS6KA6

646

Q9UK32
ELGNDWDSATKQLLG

PARP4

1691

Q9UKK3
IDEDGNNQWPEGLKF

IPO5

121

O00410
NKRKGFNEGLWEIEN

HDGFL3

76

Q9Y3E1
FNEGLWEIENNPGVK

HDGFL3

81

Q9Y3E1
EIEENPKDNAWNSGI

LRRIQ1

641

Q96JM4
AEEIKQGNDNGVLEW

MARCHF1

181

Q8TCQ1
DGLDQNDWAIDNVLI

RELN

2646

P78509
QALGLGEDWNVEKGT

PLOD1

56

Q02809
NGDKWEAEIAANIQA

NDUFS8

191

O00217
NQDGWDGKQENEERL

KAT6A

456

Q92794
LNVWLGIKNEDADEN

PIK3R3

326

Q92569
EQLLDCEGEDGWNKL

RGPD3

136

A6NKT7
QVKNDLSGGVLNDWS

EDA

261

Q92838
GEAIANENWDLKEEI

CTNNAL1

86

Q9UBT7
DSTGQQVWQDLLQDG

GBA2

356

Q9HCG7
EILWQHNDKNIGGDE

CD3E

56

P07766
GWLDQEDQEAPLQKG

MAP7D3

666

Q8IWC1
ILNKENQDDDGFWEG

FCHSD2

596

O94868
NQEEQEVETDWGLLK

CAPN6

236

Q9Y6Q1
DILEQVGESGWFQKQ

SLC22A1

6

O15245
GKWQQQGDLQDTKEN

CHGB

481

P05060
KSGQDQLDSQQEGWV

CEP131

541

Q9UPN4
IENGDGISEPDWQIK

MAP3K19

756

Q56UN5
FVRGWLKGQQEDKQD

OTOF

1761

Q9HC10
QLGVPVNDKDDAGWS

PSMD10

61

O75832
QDQIAVGEDGFKQWD

NMRK2

41

Q9NPI5
EGKAWGNQTIQADEK

USH2A

4196

O75445
EQLLDCEGEDGWNKL

RGPD4

136

Q7Z3J3
GEVGDWKNLFSEIQN

SULT6B1

261

Q6IMI4
NEIQKNIDGWEGKDI

SOS2

421

Q07890
VEIKGDDQLSGAQQW

PRCC

411

Q92733
QVQGKEWLELEEDAQ

STRIP2

91

Q9ULQ0
KAAEQGWVDGQLQLG

SEL1L

476

Q9UBV2
EDEQGDENKARGNWS

SLC6A5

181

Q9Y345
GIKNDDKNILTTWGD

MIA3

371

Q5JRA6
QEEGSLGEAWAQVKK

GAS7

266

O60861
IQRGIWDGDAKAVQQ

PRDM8

6

Q9NQV8
QWKDDLAEEDQQAGE

KCNV2

66

Q8TDN2
EQNGKQKWREEGEAG

NANOGNB

56

Q7Z5D8
QFADGKPGDQILDWQ

PLXDC2

26

Q6UX71
GGIDNDIKVWDLRQN

SNRNP40

211

Q96DI7
QKNIDGWEGKDIGQC

SOS1

426

Q07889
GKPELWSQDEVEQAG

STRC

1376

Q7RTU9
GALWGELQDNSQKKV

SPTBN5

2766

Q9NRC6
EGEKEFDQNVKLWGV

CHORDC1

271

Q9UHD1
GFNEGLWEIDNNPKV

PSIP1

76

O75475
KLVVWEAAQNGADEG

UBAP2

211

Q5T6F2
EWQNKSEFEGQQGLK

ZNF540

121

Q8NDQ6
GGKEDLIWELLNQAQ

TF

276

P02787
WDLENGKQIKSIDAG

WDR61

91

Q9GZS3
GNKASVWEELIENGK

TEP1

506

Q99973
KPENLLVWDGAAGEQ

SPEG

1721

Q15772
LQDQLEKTGENKGWS

STAU2

381

Q9NUL3
SNQEGWKKESQQDNG

STAR

91

P49675
QNEDIEAICLGQGWA

WDHD1

531

O75717
EQKGIESDWQGLLVG

FGD6

666

Q6ZV73
WPGENENGAEKVQEI

XRN1

1016

Q8IZH2
TQNNAEIWNGSGKEA

TTC41P

1201

Q6P2S7
GQVLVIEQKNEDGTW

USP15

206

Q9Y4E8
NGSWDLNEDLAKILG

VWA5A

691

O00534
QGKELWQEGREFLQD

ZNF705EP

61

A8MWA4
SKQDRENEEGDTGNW

ZC3H4

791

Q9UPT8
DKNVQEPEQGEAWKS

ZKSCAN3

451

Q9BRR0
GNWKHEGQVEDLQEN

ZNF835

16

Q9Y2P0
REQQQWGLEDEKIAG

ZKSCAN2

326

Q63HK3
TWEGIQAGKELEEQH

TALDO1

146

P37837
GGLTWQVAKLDGEEQ

SUOX

466

P51687
NVQNAEGTKWGEEAL

ZBTB38

646

Q8NAP3
NADEVIWLLGDGQAQ

TGM7

401

Q96PF1
GEQIEVFANKLGEQW

THOC1

571

Q96FV9
KNGWGEEVDQTKNSN

TNRC6B

746

Q9UPQ9
HENNEDDGVLGWNIQ

ZNF114

171

Q8NC26
GDKEELGNSWQTDQD

ZAN

1311

Q9Y493
AIWNGGQDIVADPKD

LIPK

336

Q5VXJ0
ADGLWNQKILFEEQD

NLRP12

466

P59046
GTNALVEWQAPKDDG

MYBPC2

946

Q14324