Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC2A8 SLC6A16 SLC35A1 SLC6A15 SLC10A7 SLCO6A1 SLC6A4 SLC12A1 SLC18A1	2.65e-05	296	105	9	GO:0015291
GeneOntologyMolecularFunction	diacylglycerol-dependent serine/threonine kinase activity	PRKD3 PRKCH PRKD1	7.53e-05	16	105	3	GO:0004697
GeneOntologyMolecularFunction	MAP kinase activity	MAPK11 MAPK9 MAPK10	7.53e-05	16	105	3	GO:0004707
GeneOntologyMolecularFunction	serotonin:sodium:chloride symporter activity	SLC6A4 SLC18A1	8.19e-05	3	105	2	GO:0005335
GeneOntologyMolecularFunction	JUN kinase activity	MAPK9 MAPK10	8.19e-05	3	105	2	GO:0004705
GeneOntologyMolecularFunction	sodium:chloride symporter activity	SLC6A4 SLC12A1 SLC18A1	9.11e-05	17	105	3	GO:0015378
GeneOntologyMolecularFunction	transporter activity	VMP1 CACNA1D SLC2A8 SLC6A16 FLVCR1 SLC35A1 SLC6A15 SLC10A7 SLCO6A1 GJD4 SLC6A4 SLC12A1 SLC18A1 TMEM37 APOL4 TRPV3 TMEM184B SLC27A2	1.26e-04	1289	105	18	GO:0005215
GeneOntologyMolecularFunction	protein serine kinase activity	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	1.27e-04	363	105	9	GO:0106310
GeneOntologyMolecularFunction	monoatomic anion:sodium symporter activity	SLC6A4 SLC12A1 SLC18A1	1.29e-04	19	105	3	GO:0015373
GeneOntologyMolecularFunction	symporter activity	SLC6A16 SLC6A15 SLC10A7 SLC6A4 SLC12A1 SLC18A1	1.42e-04	150	105	6	GO:0015293
GeneOntologyMolecularFunction	neurotransmitter transmembrane transporter activity	SLC6A16 SLC6A15 SLC6A4	1.75e-04	21	105	3	GO:0005326
GeneOntologyMolecularFunction	chloride:monoatomic cation symporter activity	SLC6A4 SLC12A1 SLC18A1	2.32e-04	23	105	3	GO:0015377
GeneOntologyMolecularFunction	monoatomic anion:monoatomic cation symporter activity	SLC6A4 SLC12A1 SLC18A1	3.36e-04	26	105	3	GO:0015296
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1D SLC2A8 SLC6A16 FLVCR1 SLC35A1 SLC6A15 SLC10A7 SLCO6A1 GJD4 SLC6A4 SLC12A1 SLC18A1 TMEM37 APOL4 TRPV3 SLC27A2	4.32e-04	1180	105	16	GO:0022857
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	5.78e-04	446	105	9	GO:0004674
GeneOntologyMolecularFunction	complement binding	CR2 C4A C4B	6.27e-04	32	105	3	GO:0001848
GeneOntologyMolecularFunction	G protein-coupled receptor activity	NPBWR1 GPR18 OR4S2 TAAR3P TAS2R38 ACKR4 PTGER1 OR1J4 AR CXCR6 BRS3 OPN5 TAAR1	7.42e-04	884	105	13	GO:0004930
GeneOntologyMolecularFunction	trace-amine receptor activity	TAAR3P TAAR1	7.51e-04	8	105	2	GO:0001594
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC6A15 SLC6A4 SLC12A1 SLC18A1	8.80e-04	81	105	4	GO:0015370
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC2A8 SLC6A16 SLC35A1 SLC6A15 SLC10A7 SLCO6A1 SLC6A4 SLC12A1 SLC18A1	9.30e-04	477	105	9	GO:0022804
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	1.20e-03	10	105	2	GO:0001849
GeneOntologyMolecularFunction	monoamine transmembrane transporter activity	SLC6A4 SLC18A1	1.75e-03	12	105	2	GO:0008504
GeneOntologyCellularComponent	BRCA1-BARD1 complex	BARD1 BRCA1	2.55e-05	2	106	2	GO:0031436
GeneOntologyCellularComponent	BRCA1-B complex	BARD1 BRCA1	1.52e-04	4	106	2	GO:0070532
GeneOntologyCellularComponent	BRCA1-C complex	BARD1 BRCA1	3.77e-04	6	106	2	GO:0070533
GeneOntologyCellularComponent	symbiont cell surface	C4A C4B	6.99e-04	8	106	2	GO:0106139
GeneOntologyCellularComponent	BRCA1-A complex	BARD1 BRCA1	6.99e-04	8	106	2	GO:0070531
GeneOntologyCellularComponent	other organism part	C4A C4B	8.96e-04	9	106	2	GO:0044217
Domain	MAP_kinase_CS	MAPK11 MAPK9 MAPK10	3.56e-05	12	104	3	IPR003527
Domain	MAPK	MAPK11 MAPK9 MAPK10	3.56e-05	12	104	3	PS01351
Domain	Protein_Kinase_C_mu-related	PRKD3 PRKD1	9.18e-05	3	104	2	IPR015727
Domain	NA_NEUROTRAN_SYMP_2	SLC6A16 SLC6A15 SLC6A4	1.29e-04	18	104	3	PS00754
Domain	SNF	SLC6A16 SLC6A15 SLC6A4	1.52e-04	19	104	3	PF00209
Domain	NA_NEUROTRAN_SYMP_1	SLC6A16 SLC6A15 SLC6A4	1.52e-04	19	104	3	PS00610
Domain	NA_NEUROTRAN_SYMP_3	SLC6A16 SLC6A15 SLC6A4	1.52e-04	19	104	3	PS50267
Domain	Na/ntran_symport	SLC6A16 SLC6A15 SLC6A4	1.52e-04	19	104	3	IPR000175
Domain	Ser/Thr_kinase_AS	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	1.72e-04	357	104	9	IPR008271
Domain	S_TKc	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	1.79e-04	359	104	9	SM00220
Domain	PROTEIN_KINASE_ST	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	1.90e-04	362	104	9	PS00108
Domain	DAG/PE-bd	PRKD3 PRKCH PRKD1	2.07e-04	21	104	3	IPR020454
Domain	Pkinase	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	2.78e-04	381	104	9	PF00069
Domain	C1_1	PRKD3 PRKCH UNC13C PRKD1	2.86e-04	57	104	4	PF00130
Domain	Anaphylatoxin_comp_syst	C4A C4B	3.04e-04	5	104	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	3.04e-04	5	104	2	IPR001840
Domain	MAPK_JNK	MAPK9 MAPK10	3.04e-04	5	104	2	IPR008351
Domain	ZF_DAG_PE_1	PRKD3 PRKCH UNC13C PRKD1	4.46e-04	64	104	4	PS00479
Domain	ZF_DAG_PE_2	PRKD3 PRKCH UNC13C PRKD1	4.46e-04	64	104	4	PS50081
Domain	C1	PRKD3 PRKCH UNC13C PRKD1	4.73e-04	65	104	4	SM00109
Domain	PE/DAG-bd	PRKD3 PRKCH UNC13C PRKD1	5.02e-04	66	104	4	IPR002219
Domain	ANATO	C4A C4B	6.33e-04	7	104	2	SM00104
Domain	ANATO	C4A C4B	6.33e-04	7	104	2	PF01821
Domain	TAAR_fam	TAAR3P TAAR1	6.33e-04	7	104	2	IPR009132
Domain	ANAPHYLATOXIN_2	C4A C4B	6.33e-04	7	104	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	6.33e-04	7	104	2	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B	6.33e-04	7	104	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	8.41e-04	8	104	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	8.41e-04	8	104	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	8.41e-04	8	104	2	IPR019742
Domain	PROTEIN_KINASE_ATP	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	1.06e-03	459	104	9	PS00107
Domain	A2M_N	C4A C4B	1.34e-03	10	104	2	PF01835
Domain	A2M_N	C4A C4B	1.34e-03	10	104	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	1.34e-03	10	104	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	1.34e-03	10	104	2	PS00477
Domain	A2M	C4A C4B	1.34e-03	10	104	2	PF00207
Domain	A2M_N_2	C4A C4B	1.34e-03	10	104	2	IPR011625
Domain	A2M_comp	C4A C4B	1.34e-03	10	104	2	IPR011626
Domain	A2M_N_2	C4A C4B	1.34e-03	10	104	2	PF07703
Domain	A2M_recep	C4A C4B	1.34e-03	10	104	2	PF07677
Domain	A2M_comp	C4A C4B	1.34e-03	10	104	2	PF07678
Domain	Macroglobln_a2	C4A C4B	1.34e-03	10	104	2	IPR001599
Domain	7tm_1	NPBWR1 GPR18 OR4S2 TAAR3P ACKR4 PTGER1 OR1J4 CXCR6 BRS3 OPN5 TAAR1	1.37e-03	677	104	11	PF00001
Domain	G_PROTEIN_RECEP_F1_1	NPBWR1 GPR18 OR4S2 TAAR3P ACKR4 PTGER1 OR1J4 CXCR6 BRS3 OPN5 TAAR1	1.51e-03	685	104	11	PS00237
Domain	G_PROTEIN_RECEP_F1_2	NPBWR1 GPR18 OR4S2 TAAR3P ACKR4 PTGER1 OR1J4 CXCR6 BRS3 OPN5 TAAR1	1.61e-03	691	104	11	PS50262
Domain	GPCR_Rhodpsn	NPBWR1 GPR18 OR4S2 TAAR3P ACKR4 PTGER1 OR1J4 CXCR6 BRS3 OPN5 TAAR1	1.63e-03	692	104	11	IPR000276
Domain	Prot_kinase_dom	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	1.64e-03	489	104	9	IPR000719
Domain	PROTEIN_KINASE_DOM	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	1.73e-03	493	104	9	PS50011
Domain	Kinase-like_dom	MINK1 MAP3K5 PRKD3 PRKCH PRKD1 CDK11B MAPK11 MAPK9 MAPK10	3.27e-03	542	104	9	IPR011009
Domain	Chemokine_rcpt	ACKR4 CXCR6	3.50e-03	16	104	2	IPR000355
Domain	Disintegrin_CS	ADAM33 ADAM2	3.50e-03	16	104	2	IPR018358
Domain	C345C	C4A C4B	3.95e-03	17	104	2	SM00643
Domain	GPCR_Rhodpsn_7TM	NPBWR1 GPR18 OR4S2 ACKR4 PTGER1 OR1J4 CXCR6 BRS3 OPN5 TAAR1	4.17e-03	670	104	10	IPR017452
Domain	ADAM_CR	ADAM33 ADAM2	4.43e-03	18	104	2	PF08516
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	4.43e-03	18	104	2	IPR008930
Domain	NTR	C4A C4B	4.94e-03	19	104	2	PF01759
Domain	BRCT	BARD1 BRCA1	4.94e-03	19	104	2	PF00533
Domain	Netrin_module_non-TIMP	C4A C4B	4.94e-03	19	104	2	IPR018933
Domain	-	ADAM33 ADAM2	5.47e-03	20	104	2	4.10.70.10
Pathway	KEGG_MEDICUS_ENV_FACTOR_PARAQUAT_TO_FAS_JNK_SIGNALING_PATHWAY	MAP3K5 MAPK9 MAPK10	1.88e-06	5	82	3	M49021
Pathway	REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE	MINK1 MAP3K5 MAPK11 MAPK9 MAPK10	2.22e-06	37	82	5	MM14899
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY	MAP3K5 MAPK9 MAPK10	3.75e-06	6	82	3	M47698
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY	MAP3K5 MAPK9 MAPK10	3.75e-06	6	82	3	M47712
Pathway	KEGG_MEDICUS_REFERENCE_IRE1A_JNK_SIGNALING_PATHWAY	MAP3K5 MAPK9 MAPK10	6.53e-06	7	82	3	M47697
Pathway	KEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY	MAP3K5 MAPK9 MAPK10	6.53e-06	7	82	3	M47711
Pathway	KEGG_MEDICUS_ENV_FACTOR_METALS_TO_JNK_SIGNALING_PATHWAY	MAP3K5 MAPK9 MAPK10	1.04e-05	8	82	3	M47814
Pathway	REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS	MAPK11 MAPK9 MAPK10	2.21e-05	10	82	3	MM15135
Pathway	REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS	MAPK11 MAPK9 MAPK10	2.21e-05	10	82	3	M13962
Pathway	WP_OXIDATIVE_DAMAGE_RESPONSE	CR2 C4A C4B MAPK10	1.01e-04	42	82	4	MM15945
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	NPBWR1 GPR18 TAAR3P ACKR4 PTGER1 CXCR6 BRS3 OPN5 TAAR1	1.32e-04	333	82	9	MM14963
Pathway	REACTOME_GPCR_LIGAND_BINDING	NPBWR1 GPR18 TAAR3P TAS2R38 ACKR4 PTGER1 CXCR6 BRS3 OPN5 TAAR1	1.89e-04	430	82	10	MM15160
Pathway	REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR	HUS1 APBB1 BARD1 BRCA1 HERC2 POLQ	2.04e-04	146	82	6	MM15292
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY	MAPK9 MAPK10	3.30e-04	5	82	2	M47570
Pathway	KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_TNF_JNK_SIGNALING_PATHWAY	MAPK9 MAPK10	3.30e-04	5	82	2	M49005
Pathway	REACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE	APBB1 BARD1 BRCA1 HERC2	3.32e-04	57	82	4	MM15298
Pathway	WP_MAPK_SIGNALING_PATHWAY	MINK1 MAP3K5 TMEM37 PRKCH MAPK9 MAPK10	3.35e-04	160	82	6	MM15990
Pathway	WP_INSULIN_SIGNALING	MINK1 MAP3K5 PRKCH MAPK11 MAPK9 MAPK10	3.35e-04	160	82	6	MM15956
Pathway	WP_INSULIN_SIGNALING	MINK1 MAP3K5 PRKCH MAPK11 MAPK9 MAPK10	3.35e-04	160	82	6	M39482
Pathway	REACTOME_DNA_REPAIR	ERCC5 HUS1 APBB1 USP43 BARD1 BRCA1 HERC2 POLQ	3.57e-04	301	82	8	MM15433
Pathway	PID_ATF2_PATHWAY	CBFB BRCA1 MAPK11 MAPK9	3.79e-04	59	82	4	M166
Pathway	WP_SIDS_SUSCEPTIBILITY_PATHWAYS	AR SLC6A4 C4A C4B	3.79e-04	59	82	4	MM15838
Pathway	WP_WNT_SIGNALING	PRKCH PRKD1 MAPK9 MAPK10	4.31e-04	61	82	4	MM15893
Pathway	KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY	MAPK11 MAPK9 MAPK10	4.48e-04	26	82	3	M47565
Pathway	REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR	HUS1 APBB1 BARD1 BRCA1 HERC2 POLQ	4.62e-04	170	82	6	M27582
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY	MAPK9 MAPK10	4.94e-04	6	82	2	M47680
Pathway	WP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING	MAPK11 MAPK9 MAPK10	5.60e-04	28	82	3	M39572
Pathway	REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES	MAPK11 MAPK9 MAPK10	5.60e-04	28	82	3	MM15132
Pathway	REACTOME_HOMOLOGY_DIRECTED_REPAIR	HUS1 BARD1 BRCA1 HERC2 POLQ	5.70e-04	116	82	5	MM15294
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	PRKCH PRKD1 MAPK11 MAPK9 MAPK10	6.16e-04	118	82	5	M39852
Pathway	WP_CANNABINOID_RECEPTOR_SIGNALING	MAPK11 MAPK9 MAPK10	6.21e-04	29	82	3	M39676
Pathway	REACTOME_CELLULAR_SENESCENCE	MINK1 MAP3K5 MAPK11 MAPK9 MAPK10	6.40e-04	119	82	5	MM14901
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	NPBWR1 GPR18 ACKR4 PTGER1 CXCR6 BRS3 OPN5 TAAR1	6.55e-04	330	82	8	M18334
Pathway	REACTOME_DNA_REPAIR	ERCC5 HUS1 APBB1 USP43 BARD1 BRCA1 HERC2 POLQ	6.82e-04	332	82	8	M15434
Pathway	REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT	CBFB AR	6.89e-04	7	82	2	MM15533
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	6.89e-04	7	82	2	MM14685
Pathway	REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES	MAPK11 MAPK9 MAPK10	7.58e-04	31	82	3	M15195
Pathway	PID_CD40_PATHWAY	MAPK11 MAPK9 MAPK10	7.58e-04	31	82	3	M45
Pathway	REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE	MINK1 MAP3K5 MAPK11 MAPK9 MAPK10	8.00e-04	125	82	5	M27186
Pathway	REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT	HUS1 BARD1 BRCA1 HERC2	8.10e-04	72	82	4	MM15381
Pathway	KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION	BARD1 BRCA1 RAD54L	9.13e-04	33	82	3	M47842
Pathway	BIOCARTA_BARD1_PATHWAY	BARD1 BRCA1	9.15e-04	8	82	2	M22050
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	9.15e-04	8	82	2	M47872
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	9.15e-04	8	82	2	M27031
Pathway	REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS	HUS1 BARD1 BRCA1 HERC2	9.45e-04	75	82	4	MM15299
Pathway	BIOCARTA_MAPK_PATHWAY	MAP3K5 MAPK11 MAPK9 MAPK10	9.93e-04	76	82	4	MM1433
Pathway	SIG_CD40PATHWAYMAP	MAPK11 MAPK9 MAPK10	9.97e-04	34	82	3	M12705
Pathway	WP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY	MINK1 MAP3K5 MAPK11 MAPK9 MAPK10	1.02e-03	132	82	5	M39338
Pathway	REACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE	APBB1 BARD1 BRCA1 HERC2	1.09e-03	78	82	4	M27589
Pathway	REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA	HUS1 BARD1 BRCA1	1.18e-03	36	82	3	MM15281
Pathway	WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING	MAPK11 MAPK9 MAPK10	1.18e-03	36	82	3	M39908
Pathway	REACTOME_SIGNALING_BY_GPCR	NPBWR1 GPR18 TAAR3P TAS2R38 ACKR4 PTGER1 CXCR6 BRS3 OPN5 PRKCH TAAR1	1.24e-03	646	82	11	MM14962
Pathway	BIOCARTA_MAPK_PATHWAY	MAP3K5 MAPK11 MAPK9 MAPK10	1.26e-03	81	82	4	M13863
Pathway	WP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR	HUS1 BARD1 BRCA1 HERC2	1.26e-03	81	82	4	M39490
Pathway	REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA	HUS1 BARD1 BRCA1	1.28e-03	37	82	3	M27568
Pathway	REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS	PRKD3 SGMS1 PRKD1	1.28e-03	37	82	3	M554
Pathway	REACTOME_HOMOLOGY_DIRECTED_REPAIR	HUS1 BARD1 BRCA1 HERC2 POLQ	1.33e-03	140	82	5	M27584
Pathway	PID_FAS_PATHWAY	MAPK11 MAPK9 MAPK10	1.38e-03	38	82	3	M94
Pathway	REACTOME_GPCR_LIGAND_BINDING	NPBWR1 GPR18 TAS2R38 ACKR4 PTGER1 CXCR6 BRS3 OPN5 TAAR1	1.44e-03	463	82	9	M507
Pathway	WP_OXIDATIVE_DAMAGE_RESPONSE	CR2 C4B MAPK10	1.60e-03	40	82	3	M39340
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	1.78e-03	11	82	2	M47874
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	1.78e-03	11	82	2	MM1430
Pathway	REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE	HUS1 BARD1 BRCA1	1.98e-03	43	82	3	M27588
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION	HUS1 BARD1 BRCA1 MAPK11	2.02e-03	92	82	4	MM15338
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION	HUS1 BARD1 BRCA1 MAPK11	2.02e-03	92	82	4	M27636
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	2.12e-03	12	82	2	MM1368
Pathway	KEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY	MAPK9 MAPK10	2.12e-03	12	82	2	M47929
Pathway	REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT	HUS1 BARD1 BRCA1 HERC2	2.18e-03	94	82	4	M1080
Pathway	REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS	HUS1 BARD1 BRCA1 HERC2	2.44e-03	97	82	4	M27590
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY	MAPK9 MAPK10	2.50e-03	13	82	2	M47594
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	2.50e-03	13	82	2	M4732
Pathway	REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ	BARD1 BRCA1 HERC2	2.56e-03	47	82	3	MM15296
Pathway	KEGG_TYPE_II_DIABETES_MELLITUS	CACNA1D MAPK9 MAPK10	2.56e-03	47	82	3	M19708
Pathway	WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS	SGMS1 MAPK9 MAPK10	2.56e-03	47	82	3	M39829
Pathway	WP_INTEGRATED_CANCER_PATHWAY	BARD1 MAP3K5 BRCA1	2.72e-03	48	82	3	M39628
Pathway	WP_WNT_SIGNALING_AND_PLURIPOTENCY	PRKCH PRKD1 MAPK9 MAPK10	2.83e-03	101	82	4	M39387
Pathway	KEGG_GNRH_SIGNALING_PATHWAY	CACNA1D MAPK11 MAPK9 MAPK10	2.83e-03	101	82	4	M1979
Pathway	WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY	PRKCH PRKD1 MAPK9 MAPK10	2.83e-03	101	82	4	MM15829
Pathway	WP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY	MAPK11 MAPK9 MAPK10	2.88e-03	49	82	3	M39543
Pathway	WP_SYNAPTIC_VESICLE_PATHWAY	SLC6A4 SLC18A1 UNC13C	3.23e-03	51	82	3	M39457
Pathway	REACTOME_DISEASES_OF_DNA_REPAIR	HUS1 BARD1 BRCA1	3.23e-03	51	82	3	M29854
Pathway	KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY	PRKD3 PRKD1	3.34e-03	15	82	2	M47816
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	3.34e-03	15	82	2	M7146
Pathway	REACTOME_SPHINGOLIPID_METABOLISM	HEXA PRKD3 SGMS1 PRKD1	3.49e-03	107	82	4	M14857
Pathway	KEGG_MEDICUS_REFERENCE_TNF_JNK_SIGNALING_PATHWAY	MAPK9 MAPK10	3.80e-03	16	82	2	M47569
Pathway	KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION_IN_ICLR	BARD1 BRCA1	3.80e-03	16	82	2	M47855
Pathway	WP_5Q35_COPY_NUMBER_VARIATION	BARD1 BRCA1 MAPK9 MAPK10	3.97e-03	111	82	4	M48089
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C4A C4B	4.30e-03	17	82	2	MM15944
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	4.30e-03	17	82	2	MM1369
Pathway	WP_GPCRS_NONODORANT	NPBWR1 GPR18 PTGER1 CXCR6 OPN5 TAAR1	4.51e-03	266	82	6	MM15843
Pubmed	Transmission of antibody-induced arthritis is independent of complement component 4 (C4) and the complement receptors 1 and 2 (CD21/35).	CR2 C4A C4B	2.99e-08	3	109	3	11857338
Pubmed	Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.	CR2 C4A C4B	1.20e-07	4	109	3	11067882
Pubmed	Antigen localization within the splenic marginal zone restores humoral immune response and IgG class switch in complement C4-deficient mice.	CR2 C4A C4B	1.20e-07	4	109	3	15477230
Pubmed	Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia.	CR2 C4A C4B	2.98e-07	5	109	3	15192652
Pubmed	Protective T cell-independent antiviral antibody responses are dependent on complement.	CR2 C4A C4B	2.98e-07	5	109	3	10523614
Pubmed	Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.	CR2 C4A C4B	2.98e-07	5	109	3	17947689
Pubmed	BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer	BARD1 BRCA1 NQO2 RAD54L	5.24e-07	21	109	4	20301425
Pubmed	CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression.	CR2 C4A C4B	5.95e-07	6	109	3	19710450
Pubmed	Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.	MAP3K5 MAPK11 MAPK9 MAPK10	6.39e-07	22	109	4	15767678
Pubmed	Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade.	MAP3K5 MAPK9 MAPK10	1.04e-06	7	109	3	12189133
Pubmed	Activation of mitogen activated protein kinases via complement receptor type 2.	CR2 MAPK9 MAPK10	1.04e-06	7	109	3	15603708
Pubmed	p38 MAPK signalling cascades: ancient roles and new functions.	MAPK11 MAPK9 MAPK10	1.04e-06	7	109	3	10878576
Pubmed	Divergent immunoglobulin g subclass activity through selective Fc receptor binding.	CR2 C4A C4B	1.66e-06	8	109	3	16322460
Pubmed	A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs.	MAPK11 MAPK9 MAPK10	1.66e-06	8	109	3	11359773
Pubmed	Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C.	PRKD3 PRKCH PRKD1	4.85e-06	11	109	3	2182321
Pubmed	Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.	BRCA1 MAPK9 MAPK10	4.85e-06	11	109	3	15123655
Pubmed	In vitro phosphorylation of human immunodeficiency virus type 1 Tat protein by protein kinase C: evidence for the phosphorylation of amino acid residue serine-46.	PRKD3 PRKCH PRKD1	4.85e-06	11	109	3	8914829
Pubmed	HIV-1 Tat protein induces interleukin-10 in human peripheral blood monocytes: involvement of protein kinase C-betaII and -delta.	PRKD3 PRKCH PRKD1	6.45e-06	12	109	3	11919157
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	9.73e-06	2	109	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	9.73e-06	2	109	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	9.73e-06	2	109	2	15998580
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	9.73e-06	2	109	2	19062096
Pubmed	Serotonin transporter (5-HTTLPR) genotypes and trinucleotide repeats of androgen receptor exert a combinatorial effect on hormonal milieu in patients with lifelong premature ejaculation.	AR SLC6A4	9.73e-06	2	109	2	30019487
Pubmed	Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks.	BARD1 BRCA1	9.73e-06	2	109	2	26350354
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	9.73e-06	2	109	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	9.73e-06	2	109	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	9.73e-06	2	109	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	9.73e-06	2	109	2	12207352
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	9.73e-06	2	109	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	9.73e-06	2	109	2	22387014
Pubmed	BARD1 regulates BRCA1 apoptotic function by a mechanism involving nuclear retention.	BARD1 BRCA1	9.73e-06	2	109	2	15265711
Pubmed	Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells.	AR BRCA1	9.73e-06	2	109	2	11016951
Pubmed	Identification of a RING protein that can interact in vivo with the BRCA1 gene product.	BARD1 BRCA1	9.73e-06	2	109	2	8944023
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	9.73e-06	2	109	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	9.73e-06	2	109	2	23918728
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	9.73e-06	2	109	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	9.73e-06	2	109	2	11726230
Pubmed	Protein kinase C (PKC)eta-mediated PKC mu activation modulates ERK and JNK signal pathways.	PRKCH PRKD1	9.73e-06	2	109	2	11741879
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	9.73e-06	2	109	2	4216347
Pubmed	Cloning and characterization of human NTT5 and v7-3: two orphan transporters of the Na+/Cl- -dependent neurotransmitter transporter gene family.	SLC6A16 SLC6A15	9.73e-06	2	109	2	11112352
Pubmed	Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites.	BARD1 BRCA1	9.73e-06	2	109	2	34726323
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	9.73e-06	2	109	2	6950384
Pubmed	Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress.	BARD1 BRCA1	9.73e-06	2	109	2	28262780
Pubmed	Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11.	AR CDK11B	9.73e-06	2	109	2	28262798
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	9.73e-06	2	109	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	9.73e-06	2	109	2	8428773
Pubmed	BRCA1 DNA-binding activity is stimulated by BARD1.	BARD1 BRCA1	9.73e-06	2	109	2	16489000
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	9.73e-06	2	109	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	9.73e-06	2	109	2	21345967
Pubmed	Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice.	MAPK9 MAPK10	9.73e-06	2	109	2	29899326
Pubmed	BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.	BARD1 BRCA1	9.73e-06	2	109	2	14976165
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	9.73e-06	2	109	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	9.73e-06	2	109	2	2302180
Pubmed	CAG repeat length in exon 1 of the androgen receptor gene is related to age of diagnosis but not germ line BRCA1 mutation status in ovarian cancer.	AR BRCA1	9.73e-06	2	109	2	16515589
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	9.73e-06	2	109	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	9.73e-06	2	109	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	9.73e-06	2	109	2	29080553
Pubmed	JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration.	MAPK9 MAPK10	9.73e-06	2	109	2	19014392
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	9.73e-06	2	109	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	9.73e-06	2	109	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	9.73e-06	2	109	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	9.73e-06	2	109	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	9.73e-06	2	109	2	6149581
Pubmed	Identification of residues required for the interaction of BARD1 with BRCA1.	BARD1 BRCA1	9.73e-06	2	109	2	11773071
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	9.73e-06	2	109	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	9.73e-06	2	109	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	9.73e-06	2	109	2	2387317
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	9.73e-06	2	109	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	9.73e-06	2	109	2	7365238
Pubmed	BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks.	BARD1 BRCA1	9.73e-06	2	109	2	14560035
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	9.73e-06	2	109	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	9.73e-06	2	109	2	17971360
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	9.73e-06	2	109	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	9.73e-06	2	109	2	17971229
Pubmed	The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.	BARD1 BRCA1	9.73e-06	2	109	2	30917004
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	9.73e-06	2	109	2	6881182
Pubmed	Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains.	BARD1 BRCA1	9.73e-06	2	109	2	9342365
Pubmed	Nuclear-cytoplasmic shuttling of BARD1 contributes to its proapoptotic activity and is regulated by dimerization with BRCA1.	BARD1 BRCA1	9.73e-06	2	109	2	14647430
Pubmed	Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface.	BARD1 BRCA1	9.73e-06	2	109	2	35534113
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	9.73e-06	2	109	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	9.73e-06	2	109	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	9.73e-06	2	109	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	9.73e-06	2	109	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	9.73e-06	2	109	2	28873507
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	9.73e-06	2	109	2	276882
Pubmed	Re-engineering a split-GFP reassembly screen to examine RING-domain interactions between BARD1 and BRCA1 mutants observed in cancer patients.	BARD1 BRCA1	9.73e-06	2	109	2	18493658
Pubmed	Cav1.3 channel α1D protein is overexpressed and modulates androgen receptor transactivation in prostate cancers.	CACNA1D AR	9.73e-06	2	109	2	24054868
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	9.73e-06	2	109	2	6832377
Pubmed	Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.	BARD1 BRCA1	9.73e-06	2	109	2	34102105
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	9.73e-06	2	109	2	3794341
Pubmed	Quantitative proteomic identification of the BRCA1 ubiquitination substrates.	BARD1 BRCA1	9.73e-06	2	109	2	21950761
Pubmed	The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.	BARD1 BRCA1	9.73e-06	2	109	2	18443292
Pubmed	KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS.	MAPK9 MAPK10	9.73e-06	2	109	2	28871032
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	9.73e-06	2	109	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	9.73e-06	2	109	2	32691186
Pubmed	Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1.	BARD1 BRCA1	9.73e-06	2	109	2	10026184
Pubmed	Transcriptional activation of CBFβ by CDK11p110 is necessary to promote osteosarcoma cell proliferation.	CBFB CDK11B	9.73e-06	2	109	2	31610798
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	9.73e-06	2	109	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	9.73e-06	2	109	2	3902619
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	9.73e-06	2	109	2	7373044
Cytoband	Ensembl 112 genes in cytogenetic band chr6q23	TAAR3P MAP3K5 TAAR1 MED23	1.94e-04	119	109	4	chr6q23
GeneFamily	Solute carriers	SLC2A8 SLC6A16 FLVCR1 SLC35A1 SLC6A15 SLC10A7 SLCO6A1 SLC6A4 SLC12A1 SLC18A1 SLC27A2	3.34e-06	395	88	11	752
GeneFamily	Mitogen-activated protein kinases	MAPK11 MAPK9 MAPK10	3.08e-05	13	88	3	651
GeneFamily	Ankyrin repeat domain containing\|BRCA1 B complex	BARD1 BRCA1	1.40e-04	4	88	2	1335
GeneFamily	Complement system\|Sushi domain containing	CR2 C4A C4B	7.08e-04	36	88	3	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B CD151	7.68e-04	37	88	3	454
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	8.25e-04	9	88	2	1234
GeneFamily	Trace amine receptors	TAAR3P TAAR1	8.25e-04	9	88	2	188
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT17 GALNT5	4.20e-03	20	88	2	433
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 GJD4 BRCA1 POLQ ESPL1 RAD54L	3.41e-06	166	109	6	2642544070564debe2deb2938d2c33997bf5ef02
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR18 PRSS22 ZNF692 AR CAPN8 MAPK10	3.78e-06	169	109	6	225aec04ba762d4c55885257de03a65b63503fbb
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR18 PRSS22 ZNF692 AR CAPN8 MAPK10	3.78e-06	169	109	6	278960f940b646a788360b1c84d641a8d169896b
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D SVEP1 TXNIP PRKD1 ADAM2 GALNT5	4.93e-06	177	109	6	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BARD1 ERI2 BRCA1 POLQ ESPL1 RAD54L	5.43e-06	180	109	6	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	BARD1 CR2 BRCA1 POLQ ESPL1 RAD54L	6.35e-06	185	109	6	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	CACNA1D FRAS1 SVEP1 GALNT17 PGAP1 PRKD1	6.75e-06	187	109	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 PRSS22 MYOM3 USP43 AR SLC27A2	7.18e-06	189	109	6	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1D FRAS1 SVEP1 GALNT17 UNC13C MAPK10	7.18e-06	189	109	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1D FRAS1 SVEP1 GALNT17 PGAP1 PRKD1	7.62e-06	191	109	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1D FRAS1 SVEP1 GALNT17 PGAP1 PRKD1	7.85e-06	192	109	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D FRAS1 USP43 SGMS1 PRKD1 MAPK10	9.09e-06	197	109	6	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CACNA1D FRAS1 TMTC2 SVEP1 GALNT17 UNC13C	9.09e-06	197	109	6	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	T_cells-GZMK+GZMB+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	BARD1 ERI2 BRCA1 POLQ ESPL1 RAD54L	9.36e-06	198	109	6	085ba270f9defbf5ef45108c6d870e1d7c428479
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	BARD1 ERI2 BRCA1 POLQ ESPL1 RAD54L	9.91e-06	200	109	6	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	BARD1 ERI2 BRCA1 PRKD1 POLQ ESPL1	9.91e-06	200	109	6	31dd81df9aa754a1e69b905bf9b8ce73ff8175aa
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	BARD1 ERI2 BRCA1 POLQ ESPL1 RAD54L	9.91e-06	200	109	6	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells-Neuroepithelial_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	BARD1 ERI2 BRCA1 PRKD1 POLQ ESPL1	9.91e-06	200	109	6	54174a485a82480726fa06efa6e050ddea77cb3c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nts\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NPBWR1 USP29 TMTC2 CBFB CR2	1.53e-05	127	109	5	ace2944328529fa029ee56c7ad3b0f283511d3bb
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NLRP12 STEAP4 NLRP10 C4A C4B	5.84e-05	168	109	5	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BARD1 ERI2 POLQ ESPL1 RAD54L	6.01e-05	169	109	5	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 BRCA1 POLQ ESPL1 RAD54L	6.71e-05	173	109	5	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RAB19 MTMR12 SNCAIP SLC18A1 POLQ	6.89e-05	174	109	5	009e88a6c79689a5d88b0af50aa89aa03b33f800
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ERI2 POLQ MAPK10 ESPL1 RAD54L	7.47e-05	177	109	5	844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ERI2 POLQ MAPK10 ESPL1 RAD54L	7.47e-05	177	109	5	26c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 BRCA1 POLQ ESPL1 RAD54L	7.88e-05	179	109	5	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 BRCA1 POLQ ESPL1 RAD54L	8.09e-05	180	109	5	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	P28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BARD1 SLC6A15 BRCA1 ESPL1 RAD54L	8.30e-05	181	109	5	e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCell	P28-Endothelial-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BARD1 SLC6A15 BRCA1 ESPL1 RAD54L	8.30e-05	181	109	5	2be3d44619adb25d339e7a27b500a56e07e8de01
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STEAP4 SVEP1 GALNT17 TRPV3 C4B	8.30e-05	181	109	5	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STEAP4 SVEP1 GALNT17 TRPV3 C4B	8.30e-05	181	109	5	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 ERI2 UNC13C POLQ ESPL1	8.52e-05	182	109	5	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 SLC12A1 PRKD1 MAPK10 SLC27A2	8.52e-05	182	109	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	Control-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	PRSS22 STEAP4 CAPN8 NECTIN4 GALNT5	9.20e-05	185	109	5	9a793e6016295a63820e9d7563f195494ac692e7
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	VMP1 VPS13C SLC10A7 POLQ SLC27A2	9.20e-05	185	109	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 BRCA1 POLQ ESPL1 RAD54L	9.20e-05	185	109	5	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 PRSS22 TMTC2 UNC13C LINC02694	9.44e-05	186	109	5	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	STEAP4 ACKR4 AR SVEP1 C4B	9.44e-05	186	109	5	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B GPR18 CR2 PGAP1 MAPK11	9.44e-05	186	109	5	664295cd508dc3894d55da7e9d9cd75bf1432f52
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B GPR18 CR2 PGAP1 MAPK11	9.44e-05	186	109	5	b30eb0c1673ca1ebc9b6248877d86fd6d6d14470
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	STEAP4 ACKR4 AR SVEP1 C4B	9.44e-05	186	109	5	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 SVEP1 APOL4 UNC13C PRKD1	9.68e-05	187	109	5	f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 SVEP1 APOL4 UNC13C PRKD1	9.68e-05	187	109	5	02e7246ef5ad41773d14426254e139b156d45c1d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 SVEP1 BRCA1 POLQ RAD54L	9.68e-05	187	109	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 SVEP1 BRCA1 POLQ RAD54L	9.68e-05	187	109	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 SVEP1 APOL4 UNC13C PRKD1	9.68e-05	187	109	5	08c73d125e0638c9e9878165bba2442c266c8a48
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BARD1 BRCA1 POLQ ESPL1 RAD54L	9.68e-05	187	109	5	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	CF-Lymphoid-T_cell_&_NK_cell\|Lymphoid / Disease state, Lineage and Cell class	MAP3K5 CXCR6 PRKCH LINC02694 SLC27A2	9.93e-05	188	109	5	15057036b46c9df621ec4955aa94ca3036245d45
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ERI2 BRCA1 POLQ ESPL1 RAD54L	9.93e-05	188	109	5	f5102e8d95506c25c675094b86162a6a50087b64
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PTGER1 SVEP1 GALNT17 PRKD1	1.02e-04	189	109	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 TMTC2 PTGER1 UNC13C MAPK10	1.02e-04	189	109	5	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.02e-04	189	109	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 PRSS22 TMTC2 PTGER1 PGAP1	1.04e-04	190	109	5	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CBFB BRCA1 POLQ ESPL1 RAD54L	1.04e-04	190	109	5	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T\|GI_small-bowel / Manually curated celltypes from each tissue	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.07e-04	191	109	5	e642fa7395c05fb53324c9d46bbc52f89fc9673f
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 STEAP4 CAPN8 NECTIN4 MAPK10	1.07e-04	191	109	5	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 TMTC2 EFCAB14 PTGER1 TXNIP	1.07e-04	191	109	5	0a0719a0a49ae0099d61e22585ac74c10c24b4a2
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Control / Condition, Lineage and Cell class	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.12e-04	193	109	5	33d409d6ed1c606337248587ad997ac5f67f081d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 CAPN8 SGMS1 SLC12A1 PRKD1	1.12e-04	193	109	5	263d185af6ed80e639f864e4966268e0862c61dc
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.12e-04	193	109	5	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 CAPN8 SGMS1 SLC12A1 PRKD1	1.12e-04	193	109	5	80e058c224749b5fe0ba3e944b48317c2371cb63
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 CAPN8 SGMS1 SLC12A1 PRKD1	1.12e-04	193	109	5	b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	CACNA1D FRAS1 SVEP1 GALNT17 UNC13C	1.12e-04	193	109	5	acad568621ed677031797b8c2e34dafea798d681
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.12e-04	193	109	5	e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1D SVEP1 GALNT17 PGAP1 PRKD1	1.15e-04	194	109	5	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	BRCA1 CXCR6 POLQ RAD54L SLC27A2	1.15e-04	194	109	5	17af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLC18A1 UNC13C ESPL1 ALDH7A1 RAD54L	1.15e-04	194	109	5	d024cd75a97f048257e49cee9190fb2e79202ee2
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	BRCA1 CXCR6 POLQ RAD54L SLC27A2	1.15e-04	194	109	5	3c385d93c5fe1a7817813c492f79fdb94d887357
ToppCell	3'_v3-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.15e-04	194	109	5	bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCell	Control-Lymphoid_T/NK-T/NK_proliferative\|Control / Disease group, lineage and cell class	BRCA1 POLQ ESPL1 RAD54L SLC27A2	1.15e-04	194	109	5	9bbb124001fba7450f4639f47f9b720a483e7242
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	CACNA1D PTGER1 SVEP1 GALNT17 UNC13C	1.15e-04	194	109	5	8fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1D FRAS1 SVEP1 GALNT17 UNC13C	1.15e-04	194	109	5	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BRCA1 POLQ ESPL1 RAD54L SLC27A2	1.15e-04	194	109	5	a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	BRCA1 CXCR6 POLQ RAD54L SLC27A2	1.15e-04	194	109	5	635d0e88f9c542a1d9363066c6cdbc6e44db76c1
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	BRCA1 POLQ ESPL1 RAD54L SLC27A2	1.15e-04	194	109	5	e14f66f7584909621b776292fbd52808273fd2ee
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	CACNA1D PTGER1 SVEP1 GALNT17 PRKD1	1.18e-04	195	109	5	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	Influenza_Severe-T/NK_proliferative\|World / Disease group and Cell class	BRCA1 POLQ ESPL1 RAD54L SLC27A2	1.18e-04	195	109	5	6f079c2d7d08110a5e1822ea861b8037eb3f62c9
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	CACNA1D FRAS1 SVEP1 GALNT17 PRKD1	1.18e-04	195	109	5	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.18e-04	195	109	5	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 PRSS22 STEAP4 CAPN8 NECTIN4	1.18e-04	195	109	5	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Healthy/Control-T/NK_proliferative\|Healthy/Control / Disease group and Cell class	BRCA1 POLQ ESPL1 RAD54L SLC27A2	1.18e-04	195	109	5	957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACKR4 TXNIP SNCAIP SGMS1 PRKCH	1.18e-04	195	109	5	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS22 STEAP4 CAPN8 NECTIN4 SLC27A2	1.21e-04	196	109	5	c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.21e-04	196	109	5	6d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.21e-04	196	109	5	bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.21e-04	196	109	5	3dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP251 PRSS22 STEAP4 CAPN8 GALNT5	1.21e-04	196	109	5	3e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCell	mLN-T_cell-gd_T\|T_cell / Region, Cell class and subclass	CACNA1D SLC10A7 PRKD3 CXCR6 TRPV3	1.21e-04	196	109	5	8f476408cd5a4ea9d25c763c66565343d7989b38
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.21e-04	196	109	5	4f649e3bfd21f21682678828673843a7d51c4ff2
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP251 PRSS22 STEAP4 CAPN8 GALNT5	1.21e-04	196	109	5	1efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.21e-04	196	109	5	799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.21e-04	196	109	5	0c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCell	Healthy-T/NK_proliferative\|Healthy / disease group, cell group and cell class	BRCA1 POLQ ESPL1 RAD54L SLC27A2	1.21e-04	196	109	5	91e44aabb2e85dcc77ddae6f7e000118d45d1de6
ToppCell	Control-Myeloid-proliferating_Myeloid_cells\|Control / Disease group,lineage and cell class （2021.01.30）	BARD1 BRCA1 POLQ ESPL1 RAD54L	1.24e-04	197	109	5	ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCell	Healthy/Control-T/NK_proliferative\|World / Disease group and Cell class	BRCA1 POLQ ESPL1 RAD54L SLC27A2	1.24e-04	197	109	5	4a4d3083938783d6f5b87da02f10e501917da0b4
ToppCell	Severe_COVID-19-Epithelial-transitional_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CFAP251 PRSS22 STEAP4 CAPN8 GALNT5	1.24e-04	197	109	5	5ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CFAP251 PRSS22 STEAP4 CAPN8 GALNT5	1.24e-04	197	109	5	08b371309cd790b171ed76cabc7d910e71cd2835
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TM9SF3 PRSS22 STEAP4 NECTIN4 GALNT5	1.24e-04	197	109	5	adb4e27d73ae2e6a39d212c0ead3ac0ad62d9131
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFAP251 PRSS22 STEAP4 CAPN8 GALNT5	1.24e-04	197	109	5	9f49feee38647bbf964974aac96fa75602186b5c
ToppCell	Healthy_donor-T/NK_proliferative\|Healthy_donor / disease group, cell group and cell class (v2)	BRCA1 POLQ ESPL1 RAD54L SLC27A2	1.24e-04	197	109	5	b6bbf87e5823fa66b4cad6a7be4f777356887b59
Drug	methyl methanesulfonate	ERCC5 HUS1 BARD1 PRKD3 BRCA1 PRKCH PRKD1 MAPK11 MAPK9 POLQ MAPK10 RAD54L	1.64e-07	364	108	12	CID000004156
Drug	AC1L1DXE	CACNA1D STEAP4 PTGER1 PRKD3 SLC6A4 SLC18A1 PRKCH TRPV3 PRKD1 MAPK9 MAPK10	1.86e-07	299	108	11	CID000002548
Drug	Ro 31-7549	PRKD3 PRKCH PRKD1 MAPK9 MAPK10	1.11e-06	39	108	5	CID000002403
Drug	AC1L1JGQ	PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	1.30e-06	73	108	6	CID000005034
Drug	AC1LDMDX	PRKD3 PRKCH PRKD1 MAPK9 MAPK10	1.82e-06	43	108	5	CID000621355
Drug	4-hydroxynonenal	ERCC5 AR MAP3K5 PRKD3 TSPAN31 TMEM37 PRKCH PRKD1 MAPK11 MAPK9 MAPK10 ALDH7A1	2.47e-06	471	108	12	CID000001693
Drug	MDL 27,032	PRKD3 PRKCH PRKD1 ALDH7A1	2.69e-06	21	108	4	CID000163812
Drug	KS-619-1	PRKD3 PRKCH PRKD1 ALDH7A1	2.69e-06	21	108	4	CID000128369
Drug	K-259-2	PRKD3 PRKCH PRKD1 ALDH7A1	2.69e-06	21	108	4	CID006438946
Drug	satratoxin H	MAPK11 MAPK9 MAPK10	3.58e-06	7	108	3	CID000434380
Drug	AC1Q5V5T	NLRP12 PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	3.73e-06	135	108	7	CID000004701
Drug	AG213	PRKD3 PRKCH C4A PRKD1 MAPK9 MAPK10	4.18e-06	89	108	6	CID005328803
Drug	SKF86002	MAPK11 MAPK9 MAPK10 ALDH7A1	4.73e-06	24	108	4	CID000005228
Drug	0-to	PTGER1 PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	4.98e-06	141	108	7	CID000002051
Drug	2,4,3',5'-tetramethoxystilbene	AR MAPK9 MAPK10 ESPL1	5.61e-06	25	108	4	ctd:C440850
Drug	phenethylamine	SLC6A4 SLC18A1 TAAR1	8.54e-06	9	108	3	ctd:C029261
Drug	SC68376	MAPK11 MAPK9 MAPK10	8.54e-06	9	108	3	CID000005174
Drug	NCDC	CACNA1D PRKD3 PRKCH PRKD1	8.98e-06	28	108	4	CID000001583
Drug	Ro-31-8425	PRKD3 PRKCH PRKD1 MAPK9 MAPK10	9.71e-06	60	108	5	CID000002404
Drug	AC1L1KC5	CACNA1D STEAP4 MAP3K5 PRKD3 BRS3 TMEM37 PRKCH TRPV3 PRKD1 MAPK11 MAPK9 MAPK10	1.01e-05	541	108	12	CID000005428
Drug	(?-Fluprostenol	PTGER1 PRKD3 SGMS1 PRKCH PRKD1	1.05e-05	61	108	5	CID000003391
Drug	diphenyleneiodonium	MAP3K5 PRKD3 TMEM37 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	1.51e-05	232	108	8	CID000003101
Drug	1-acetyl-sn-glycero-3-phosphocholine	ACKR4 AR PRKD3 SGMS1 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	1.51e-05	305	108	9	CID005311264
Drug	1iiq	NPBWR1 TAS2R38 PTGER1 SLC6A4 MAPK9 MAPK10	1.66e-05	113	108	6	CID000446293
Drug	naphthalenesulfonamide	PRKD3 SLC6A4 PRKCH PRKD1	1.76e-05	33	108	4	CID000163571
Drug	AC1L1FGW	PTGER1 PRKD3 PRKCH PRKD1	1.76e-05	33	108	4	CID000003231
Drug	noradrealine	CACNA1D AR PRKD3 SLC6A4 SLC12A1 SLC18A1 PRKCH PRKD1 MAPK11 MAPK9 MAPK10 ALDH7A1	1.85e-05	575	108	12	CID000000951
Drug	AC1NSKHR	PRKD3 PRKCH PRKD1 MAPK11	1.99e-05	34	108	4	CID005311362
Drug	Kinome_3024	MAPK9 MAPK10	2.23e-05	2	108	2	CID011539329
Drug	Kinome_3019	MAPK9 MAPK10	2.23e-05	2	108	2	CID011658882
Drug	Kinome_3025	MAPK9 MAPK10	2.23e-05	2	108	2	CID011715520
Drug	Kinome_3027	MAPK9 MAPK10	2.23e-05	2	108	2	CID011640926
Drug	Kinome_3028	MAPK9 MAPK10	2.23e-05	2	108	2	CID011590363
Drug	AC1LAIW3	PRKD3 PRKCH PRKD1 MAPK9 MAPK10	2.38e-05	72	108	5	CID000469261
Drug	AC1L9IGO	CR2 TMEM37 C4A TAAR1 MAPK11 MAPK9 MAPK10	2.82e-05	184	108	7	CID000445722
Drug	myo-inositol	HEXA CACNA1D GPR18 PTGER1 AR PRKD3 BRS3 PGAP1 PRKCH PRKD1 MAPK11 MAPK9 MAPK10 ALDH7A1	2.97e-05	811	108	14	CID000000892
Drug	apocynin	MAP3K5 PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	3.02e-05	186	108	7	CID000002214
Drug	R59022	PRKD3 TMEM37 PRKCH PRKD1 ALDH7A1	3.09e-05	76	108	5	CID000003012
Drug	Go6976	MAP3K5 PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	3.46e-05	190	108	7	CID000003501
Drug	SB-242235	MAPK11 MAPK9 MAPK10	3.64e-05	14	108	3	CID009863367
Drug	SB202474	MAPK11 MAPK9 MAPK10	3.64e-05	14	108	3	CID000005162
Drug	Fura-2AM	CACNA1D PTGER1 PRKD3 PRKCH PRKD1	3.73e-05	79	108	5	CID000105091
Drug	phloretin	CACNA1D PTGER1 PRKD3 TXNIP PRKCH PRKD1	3.83e-05	131	108	6	CID000004788
Drug	Go6983	PRKD3 PRKCH PRKD1 MAPK11	3.84e-05	40	108	4	CID000003499
Drug	procymidone	AR MAPK11 MAPK9 MAPK10	3.84e-05	40	108	4	CID000036242
Drug	ethanol	CACNA1D STEAP4 TAS2R38 PTGER1 PRKD3 SLC6A4 PRKCH C4A PRKD1 MAPK11 MAPK9 POLQ MAPK10 ALDH7A1	4.19e-05	837	108	14	CID000000702
Drug	RK-1409B	PRKD3 PRKCH PRKD1	4.53e-05	15	108	3	CID003036125
Drug	1-stearoyl-2-arachidonylglycerol	PRKD3 PRKCH PRKD1	4.53e-05	15	108	3	CID006443869
Drug	dansyl-DAG	PRKD3 PRKCH PRKD1	4.53e-05	15	108	3	CID000129493
Drug	SQ22536	PTGER1 PRKD3 PRKCH PRKD1 MAPK11 ALDH7A1	4.53e-05	135	108	6	CID000005270
Drug	N,N-dimethyl-D-erythro-sphingosine	PRKD3 TMEM37 PRKCH C4A PRKD1	4.73e-05	83	108	5	CID000004285
Drug	phosphorylcholine	CR2 PRKD3 SGMS1 PRKCH C4A PRKD1 ALDH7A1	4.94e-05	201	108	7	CID000001014
Drug	cisplatin	PRKD3 SLC18A1 PRKCH PRKD1 HERC2 MAPK11	5.34e-05	139	108	6	CID000002767
Drug	Ro 31	PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	5.78e-05	141	108	6	CID000214797
Drug	AC1L1B55	HEXA ANKRD42 STEAP4 AR PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	6.11e-05	454	108	10	CID000001287
Drug	procyanidin B2	PRKD3 PRKCH C4A PRKD1	6.14e-05	45	108	4	CID000122738
Drug	myricitrin	ERCC5 PRKD3 PRKCH PRKD1	6.14e-05	45	108	4	CID005281673
Drug	mucic acid	FLVCR1 PRKD3 PRKCH PRKD1 ALDH7A1	6.27e-05	88	108	5	CID000000607
Drug	serotonin	SLC6A16 SLC6A15 PRKD3 SLC6A4 SLC18A1 PRKCH TAAR1 PRKD1 MAPK11 MAPK9 MAPK10	6.57e-05	554	108	11	CID000005202
Drug	C6-ceramide	PRKD3 PRKCH PRKD1 MAPK9 MAPK10	6.62e-05	89	108	5	CID000375405
Drug	2-aminothiophenol	C4A C4B	6.67e-05	3	108	2	ctd:C005464
Drug	N-glyceryl-2-hexyl-3-keto-capramide	MAPK9 MAPK10	6.67e-05	3	108	2	CID011645877
Drug	benzothiazol-2-ylacetonitrile	MAPK9 MAPK10	6.67e-05	3	108	2	CID000342465
Drug	Calebin-A	MAPK9 MAPK10	6.67e-05	3	108	2	CID000637429
Drug	eye gene	CACNA1D AR MAP3K5 PRKD3 TXNIP PRKCH PRKD1 MAPK11 ALDH7A1	6.68e-05	369	108	9	CID000004782
Drug	Pc 12	NLRP12 PRKD3 SLC18A1 PRKCH PRKD1 MAPK9 MAPK10	6.71e-05	211	108	7	CID003036508
Drug	Ambotz208527-57-5	MAPK11 MAPK9 MAPK10	6.72e-05	17	108	3	CID010258704
Drug	AC1L1JQC	PRKD3 PRKCH PRKD1	6.72e-05	17	108	3	CID000005157
Drug	daphnoretin	PRKD3 PRKCH PRKD1	6.72e-05	17	108	3	CID005281406
Drug	histamine	HEXA STEAP4 CR2 SLC18A1 ADAM33 C4A TAAR1 MAPK11 MAPK9 MAPK10 ALDH7A1	7.24e-05	560	108	11	CID000000774
Drug	chloroethylclonidine	AR PRKD3 PRKCH PRKD1	7.30e-05	47	108	4	CID000104973
Drug	DENSPM	TMEM37 MAPK11 MAPK9 MAPK10	7.93e-05	48	108	4	CID000004282
Drug	dihydrosterculic acid	PRKD3 PRKCH PRKD1	8.04e-05	18	108	3	CID000160788
Drug	NSC363979	MAP3K5 MAPK9 MAPK10	8.04e-05	18	108	3	CID000183413
Drug	dipalmitin	PRKD3 PRKCH PRKD1	8.04e-05	18	108	3	CID000068149
Drug	Cgp-42700	PRKD3 PRKCH PRKD1	8.04e-05	18	108	3	CID000188390
Drug	ethylnylestradiol	HEXA SLC2A8 BARD1 STEAP4 ACKR4 AR CHST8 PRKD3 SLC6A4 TXNIP BRCA1 TMEM37 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	8.15e-05	1251	108	17	CID000003285
Drug	compound 48/80	HEXA PRKD3 PRKCH C4A PRKD1 ALDH7A1	8.45e-05	151	108	6	CID000104735
Drug	NSC150531	PRKD3 CXCR6 PRKCH PRKD1	8.61e-05	49	108	4	CID000004475
Drug	forskolin from Coleus forskohlii	CACNA1D GPR18 STEAP4 PTGER1 AR PRKD3 SLC12A1 BRCA1 PRKCH TAAR1 PRKD1 MAPK11 MAPK9 MAPK10 ALDH7A1	8.70e-05	1013	108	15	CID000003413
Drug	thiomalate	PRKD3 PRKCH PRKD1 MED23	9.32e-05	50	108	4	CID000006268
Drug	Trimethyltin ion	STEAP4 PRKD3 PRKCH PRKD1	9.32e-05	50	108	4	CID000021162
Drug	AG126	HEXA PRKD3 PRKCH PRKD1 MAPK11	9.49e-05	96	108	5	CID000002046
Drug	TAPP-Br	PRKD3 PRKCH PRKD1	9.52e-05	19	108	3	CID000160326
Drug	sapintoxin A	PRKD3 PRKCH PRKD1	9.52e-05	19	108	3	CID000108085
Drug	mepivacaine	PRKD3 SLC6A4 PRKCH PRKD1	1.01e-04	51	108	4	CID000004062
Drug	I-Q-S	PRKD3 PRKCH C4A PRKD1 MAPK11 ALDH7A1	1.01e-04	156	108	6	CID000003540
Drug	carbachol	CACNA1D PTGER1 PRKD3 BRS3 TMEM37 ADAM33 PRKCH PRKD1 MAPK11 MAPK9 MAPK10 ALDH7A1	1.04e-04	688	108	12	CID000002551
Drug	vanadyl	MAP3K5 PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10 ALDH7A1	1.09e-04	307	108	8	CID000061671
Drug	indo-1	CACNA1D PRKD3 PRKCH PRKD1 ALDH7A1	1.10e-04	99	108	5	CID000105060
Drug	lysosphingomyelin	PRKD3 PRKCH PRKD1 MAPK11 MAPK9 MAPK10	1.16e-04	160	108	6	CID000005263
Drug	inhibitor of p38 kinase	MAP3K5 MAPK11 MAPK9 MAPK10	1.17e-04	53	108	4	CID000027933
Drug	enzastaurin	PRKD3 TMEM37 PRKCH PRKD1	1.17e-04	53	108	4	CID000176166
Drug	CGP 19835A	STEAP4 PRKD3 PRKCH PRKD1	1.26e-04	54	108	4	CID005479141
Drug	debromoaplysiatoxin	PRKD3 PRKCH PRKD1	1.30e-04	21	108	3	CID000002967
Drug	broussochalcone A	PRKD3 PRKCH PRKD1	1.30e-04	21	108	3	CID006438825
Drug	JNK inhibitor VIII	MAPK9 MAPK10	1.33e-04	4	108	2	CID011624601
Drug	N1-Methyl-1,9-pyrazoloanthrone	MAPK9 MAPK10	1.33e-04	4	108	2	CID011665831
Drug	indatraline	SLC6A4 TAAR1	1.33e-04	4	108	2	ctd:C418119
Drug	AC1L1G3W	NLRP12 STEAP4 AR MAP3K5 TXNIP ADAM33 MAPK9	1.39e-04	237	108	7	CID000003514
Disease	BREAST CANCER	BARD1 BRCA1 NQO2 RAD54L	8.65e-07	21	105	4	114480
Disease	Malignant tumor of breast	BARD1 BRCA1 NQO2 RAD54L	2.49e-06	27	105	4	cv:C0006142
Disease	Breast neoplasm	BARD1 BRCA1 NQO2 RAD54L	2.49e-06	27	105	4	cv:C1458155
Disease	Familial cancer of breast	BARD1 BRCA1 NQO2 RAD54L	2.49e-06	27	105	4	cv:C0346153
Disease	cocaine abuse (implicated_via_orthology)	SLC6A4 SLC18A1	3.75e-05	3	105	2	DOID:809 (implicated_via_orthology)
Disease	response to platinum based chemotherapy, cytotoxicity measurement	FRAS1 SNCAIP	1.25e-04	5	105	2	EFO_0004647, EFO_0006952
Disease	Breast Cancer, Familial	BARD1 BRCA1 RAD54L	1.66e-04	30	105	3	C0346153
Disease	amphetamine abuse (implicated_via_orthology)	MAP3K5 SLC18A1	1.86e-04	6	105	2	DOID:670 (implicated_via_orthology)
Disease	acyl-CoA-binding domain-containing protein 6 measurement	NLRP12 TMEM37	1.86e-04	6	105	2	EFO_0801342
Disease	mitogen-activated protein kinase 8 measurement	NLRP12 MAPK10	1.86e-04	6	105	2	EFO_0020580
Disease	Parkinson's disease (implicated_via_orthology)	NPBWR1 VPS13C MAPK11 MAPK9 MAPK10	2.52e-04	157	105	5	DOID:14330 (implicated_via_orthology)
Disease	Asthma, Occupational	PRKD1 HERC2	5.54e-04	10	105	2	C0264423
Disease	retinal drusen	SVEP1 CAPN8 UNC13C	8.05e-04	51	105	3	EFO_1001155
Disease	Hereditary Breast and Ovarian Cancer Syndrome	BARD1 BRCA1	1.11e-03	14	105	2	C0677776
Disease	pancreatic adenocarcinoma (is_implicated_in)	MAPK9 MAPK10	1.28e-03	15	105	2	DOID:4074 (is_implicated_in)
Disease	nasopharynx carcinoma (is_implicated_in)	CR2 BRCA1	1.28e-03	15	105	2	DOID:9261 (is_implicated_in)
Disease	systemic lupus erythematosus (is_implicated_in)	CR2 C4A C4B	1.42e-03	62	105	3	DOID:9074 (is_implicated_in)
Disease	breast cancer (is_implicated_in)	BARD1 BRCA1 NQO2 RAD54L	2.06e-03	150	105	4	DOID:1612 (is_implicated_in)
Disease	Lupus Erythematosus, Systemic	CR2 C4A C4B	2.10e-03	71	105	3	C0024141
Disease	Deaf Mutism	CACNA1D TMTC2	2.29e-03	20	105	2	C4082305
Disease	Deafness, Acquired	CACNA1D TMTC2	2.29e-03	20	105	2	C0751068
Disease	Hearing Loss, Extreme	CACNA1D TMTC2	2.29e-03	20	105	2	C0086395
Disease	Complete Hearing Loss	CACNA1D TMTC2	2.29e-03	20	105	2	C0581883
Disease	Bilateral Deafness	CACNA1D TMTC2	2.29e-03	20	105	2	C3665473
Disease	Adenocarcinoma of prostate	AR BRCA1	2.29e-03	20	105	2	C0007112
Disease	Prelingual Deafness	CACNA1D TMTC2	2.29e-03	20	105	2	C0011052
Disease	attention deficit hyperactivity disorder (is_implicated_in)	AR SLC6A4	2.29e-03	20	105	2	DOID:1094 (is_implicated_in)
Disease	age at first sexual intercourse measurement	RAB19 CACNA1D SLC6A15 PRKD1 FBXO33 IGSF1	2.52e-03	383	105	6	EFO_0009749
Disease	schizophrenia (is_implicated_in)	SLC18A1 APOL4 TRPV3	2.74e-03	78	105	3	DOID:5419 (is_implicated_in)
Disease	Alcoholic Intoxication, Chronic	TAS2R38 AR SLC6A4 LINC02694 NQO2	2.75e-03	268	105	5	C0001973
Disease	epilepsy (implicated_via_orthology)	MINK1 SLC12A1 UNC13C ALDH7A1	2.78e-03	163	105	4	DOID:1826 (implicated_via_orthology)
Disease	Breast Carcinoma	BARD1 AR BRCA1 ADAM33 HERC2 NQO2 RAD54L	3.16e-03	538	105	7	C0678222

Protein segments in the cluster

Peptide	Gene	Start	Entry
NTALLAWKMIRDGCV	ERI2	221	A8K979
STLKCMLGILNGCWI	BARD1	616	Q99728
GIHEWVFGQVMCKSL	CXCR6	91	O00574
CIWRNGKVGLSGMAI	C4B	1471	P0C0L5
AIAMICGNVCLWKGA	ALDH7A1	206	P49419
MEGAALLKIFVVCIW	APOL4	1	Q9BPW4
QWICIDGVCMSGDKQ	ADAM2	481	Q99965
CKAVLACVGVWIMTL	GPR18	136	Q14330
IFRMEQLLTWKGTCG	ADAM33	166	Q9BZ11
GIKCFAVRSLGWVEM	APBB1	366	O00213
KDGMVQLSLAEWLCC	CAPN8	686	A6NHC0
MWSVGCIFGELLTQK	CDK11B	621	P21127
QCKWVMGSILLLVSF	TMEM37	121	Q8WXS4
VACVGLVWMQVALKE	EFCAB14	86	O75071
GHIECLQWLIKMGAD	ANKRD42	281	Q8N9B4
IAIGSICGMIKVWNY	CFAP251	621	Q8TBY9
ANVVIMLIGNKCDLW	RAB19	121	A4D1S5
GLGKTLQCITLMWTL	RAD54L	186	Q92698
AVHGWVLGKIMCKIT	ACKR4	101	Q9NPB9
VDIWSVGCIMGELVK	MAPK9	206	P45984
WFMVGIVLAIAGAKL	SLC10A7	11	Q0GE19
NEWLLKGLQTVGCMP	SLC10A7	101	Q0GE19
IWSVGCIMAELLQGK	MAPK11	206	Q15759
MLWGLVRQGLKCEGC	PRKD1	166	Q15139
MGVLKVWLGLALALA	FRAS1	1	Q86XX4
KENVDIWSVGCIMGE	MAPK10	241	P53779
SLIQKEWVMGGHCFL	MTMR12	421	Q9C0I1
CSWLQGQMERGKVVL	NLRP10	361	Q86W26
GLCGLWNEMVKDGEI	HERC2	31	O95714
LMCQVDGAWLLAGII	PRSS22	246	Q9GZN4
IITLNCNVTMVGKLW	GJD4	11	Q96KN9
QLKWLSCGFMLEIVT	FBXO33	251	Q7Z6M2
TWLGQELEKCGIDAM	KIAA0232	41	Q92628
RETCNKMLLGTWVGG	OR4S2	136	Q8NH73
VGQLVGIMVVSCICW	PTGER1	296	P34995
MILNGVCVIWKGWID	CBFB	101	Q13951
KGWIDLQRLDGMGCL	CBFB	111	Q13951
SIQGTWCKDILQTIM	MED23	706	Q9ULK4
TKVAMLICAGFLIAW	OPN5	251	Q6U736
CGEMLWGLVRQGLKC	PRKD3	171	O94806
KEDCDLENVWLMGGL	KMT2B	1176	Q9UMN6
GWLQITPQEFLCMKA	AR	796	P10275
ADMQKVRICSEGGWV	POGK	31	Q9P215
AILKGWMDRVLCQGF	NQO2	111	P16083
MKEGLCNLLVTVSWI	OR1J4	136	Q8NGS1
EWMVQLCGASVVKEL	BRCA1	1781	P38398
AQGCKMVILWLAALQ	ESPL1	521	Q14674
GQELQLRCKGWLAGM	IGSF1	696	Q8N6C5
CVIAGQGVAWTKMPV	CR2	256	P20023
ELSFKVWMCGGEIEI	GALNT5	701	Q7Z7M9
SVQLGAIEACVMWLL	POLQ	576	O75417
GLLAKWLVDCVMVRN	DENND5B	1001	Q6ZUT9
ELGIKVWLCGGSMEV	GALNT17	356	Q6IS24
KAGNIFLCVWMFIGI	FLVCR1	491	Q9Y5Y0
LIDGMCKVAINWSGG	HDAC8	126	Q9BY41
IKSWVQCGISMKILN	DDX46	371	Q7L014
GLAVMAVGIWTLALK	CD151	31	P48509
KGLASRCWENLILAM	EIF4E2	141	O60573
CGLIVKHGMTLRNWA	FAM87A	146	P0C7U9
EAWQEIMLACLPGKL	CACNA1D	1406	Q01668
CIWRNGKVGLSGMAI	C4A	1471	P0C0L4
QWPFGELMCKLIVAI	NPBWR1	101	P48145
ICSNQIMGWGEKAIE	MINK1	1261	Q8N4C8
PEQKALVIGGEACMW	HEXA	446	P06865
GGMLCTLWKAIIDFR	MAP3K5	1356	Q99683
ILWRDKIGVMVCVGI	TAS2R38	271	P59533
SKLQWVSVFMLCAGV	SLC35A1	141	P78382
KTLGIVMGVFLACWL	TAAR3P	256	Q9P1P4
SGGLNWKMTICLLAA	SLC6A15	221	Q9H2J7
LSLAACGVVRMKGLW	TMEM105	106	Q8N8V8
WCLVGAFMINGLKST	SLC6A16	276	Q9GZN6
WQGMLLAILEKCGAI	TMEM184B	261	Q9Y519
WLGLVKLGCAMACLN	SLC27A2	121	O14975
KGVATGICVLTNWLM	SLC2A8	406	Q9NY64
KLANGGVSMWCELEQ	HUS1	46	O60921
MGVQGLWKLLECSGR	ERCC5	1	P28715
LAIKNGQLECVRWMV	SNCAIP	391	Q9Y6H5
GTNIKDLCAALWILM	SLCO6A1	366	Q86UG4
ILLGISVAGMEWEAK	SLC12A1	311	Q13621
MCLQGVDLSWKAELL	PGAP1	406	Q75T13
ACGIWMITVLKQQGA	MROH2B	1026	Q7Z745
MLRCTTSGKWNVGVQ	SVEP1	541	Q4LDE5
VKAGCVWIVSMIFAL	BRS3	166	P32247
GCSNWKRVLMVLAGL	CHST8	201	Q9H2A9
CLQASVWMAGGKLRL	LINC02694	36	Q8NAA6
LGKMQIWICQPEELG	LINC01553	76	A4QN01
CQVLQQGMVKLSLWT	USP43	566	Q70EL4
GLLWGIARQGMKCLE	UNC13C	1116	Q8NB66
AIGGVKNMLLEWCRA	SMTNL1	376	A8MU46
CSMLWKEQGVTVLAV	TMTC2	181	Q8N394
MCGLGTILLEAAKEW	THUMPD2	306	Q9BTF0
MISLKVCGFIQIWSQ	USP29	1	Q9HBJ7
VCGFIQIWSQKTGMT	USP29	6	Q9HBJ7
MLVSLLLIGVAAWGK	TSPAN31	21	Q12999
ICEINGMILVGLWLI	SGMS1	186	Q86VZ5
WMLCRKQLGLVALGF	STEAP4	286	Q687X5
IKEVEILGLMCVDWQ	VPS13C	3656	Q709C8
KTLGIVMGVFLICWC	TAAR1	251	Q96RJ0
WSLGCTGLKAAMQIQ	ZNF333	136	Q96JL9
KWFMEPAVIVCLGGI	TM9SF3	441	Q9HD45
LIWAMCISVKEGIAI	TRPV3	491	Q8NET8
ILACGVAKVLWMQGS	TXNIP	46	Q9H3M7
WTIGQARSGMQKLLC	VWA8	1051	A3KMH1
QDLGGISWQLALCIM	SLC6A4	246	P31645
ALGVAMRCDIVQKIW	ZFC3H1	1771	O60293
LGGHMEQWCLLKERL	ZNF692	31	Q9BU19
FGVLANKMGRWLCSL	SLC18A1	356	P54219
KVRIEACMWGIGTAI	VMP1	186	Q96GC9
LWGIMRQGLQCKICK	PRKCH	266	P24723
GCKLRVLWLFGMDLN	NLRP12	1026	P59046
FALLNCGKNEMVIGW	MYOM3	706	Q5VTT5
QNLWHIGREGAMLKC	NECTIN4	256	Q96NY8