Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionJUN kinase binding

SPAG9 KIF5B MAPK8IP3

3.60e-0617363GO:0008432
GeneOntologyMolecularFunctionATP hydrolysis activity

SMARCA4 KIF5B SRCAP CLPB ATP8B2 SMC1B RSF1

1.17e-05441367GO:0016887
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

SMARCA4 SRCAP RSF1

4.01e-0537363GO:0140658
GeneOntologyMolecularFunctionATP-dependent activity

SMARCA4 KIF5B SRCAP CLPB ATP8B2 SMC1B RSF1

9.64e-05614367GO:0140657
GeneOntologyMolecularFunctioncytoskeletal protein binding

CEP350 PPARGC1A ROCK1 SPAG9 KIF5B PSTPIP1 NEXN ADD3 MAPK8IP3

1.09e-041099369GO:0008092
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

NCOA2 NCOA1 PPARGC1A

1.18e-0453363GO:0030331
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA2 NCOA1 PPARGC1A

1.80e-0461363GO:0030374
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA2 SMARCA4 NCOA1 PPARGC1A SRCAP

2.00e-04303365GO:0003713
GeneOntologyMolecularFunctionMAP-kinase scaffold activity

SPAG9 MAPK8IP3

2.43e-0413362GO:0005078
GeneOntologyMolecularFunctionnuclear receptor binding

NCOA2 SMARCA4 NCOA1 PPARGC1A

3.47e-04187364GO:0016922
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

SMARCA4 KIF5B SRCAP CLPB ATP8B2 SMC1B RSF1

4.03e-04775367GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

SMARCA4 KIF5B SRCAP CLPB ATP8B2 SMC1B RSF1

6.47e-04839367GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

SMARCA4 KIF5B SRCAP CLPB ATP8B2 SMC1B RSF1

6.52e-04840367GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

SMARCA4 KIF5B SRCAP CLPB ATP8B2 SMC1B RSF1

6.52e-04840367GO:0016818
GeneOntologyMolecularFunctionDNA polymerase binding

NCOA2 SMARCA4

7.81e-0423362GO:0070182
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOA2 NCOA1

7.81e-0423362GO:0046965
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA2 SMARCA4 NCOA1 PPARGC1A SPAG9 TCHH SRCAP MAPK8IP3

8.90e-041160368GO:0030674
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

SMARCA4 SRCAP RSF1

1.54e-03127363GO:0008094
GeneOntologyMolecularFunctionlncRNA binding

SMARCA4 PPARGC1A

1.81e-0335362GO:0106222
GeneOntologyMolecularFunctionmolecular adaptor activity

NCOA2 SMARCA4 NCOA1 PPARGC1A SPAG9 TCHH SRCAP MAPK8IP3

2.42e-031356368GO:0060090
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA2 SMARCA4 NCOA1 PPARGC1A SRCAP

3.18e-03562365GO:0003712
GeneOntologyMolecularFunctionhistone acetyltransferase activity

NCOA1 SRCAP

3.81e-0351362GO:0004402
GeneOntologyMolecularFunctionsignaling receptor complex adaptor activity

SPAG9 MAPK8IP3

4.26e-0354362GO:0030159
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

NCOA1 SRCAP

4.42e-0355362GO:0061733
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOA2 NCOA1

4.42e-0355362GO:0042974
GeneOntologyMolecularFunctionkinesin binding

SPAG9 MAPK8IP3

4.42e-0355362GO:0019894
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

NCOA1 SRCAP

5.24e-0360362GO:0034212
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

NCOA2 SMARCA4 NCOA1 PPARGC1A

6.51e-03417364GO:0061629
GeneOntologyMolecularFunctionactin filament binding

PSTPIP1 NEXN ADD3

7.85e-03227363GO:0051015
GeneOntologyMolecularFunctionN-acetyltransferase activity

NCOA1 SRCAP

8.71e-0378362GO:0008080
GeneOntologyBiologicalProcesscellular response to Thyroglobulin triiodothyronine

NCOA2 NCOA1

1.49e-054332GO:1904017
GeneOntologyBiologicalProcesspositive regulation of female receptivity

NCOA2 NCOA1

1.49e-054332GO:0045925
GeneOntologyBiologicalProcessneuron projection development

TNIK ROCK1 SPAG9 UPF3B KIF5B ITGA4 HLA-C NEXN MINK1 MAPK8IP3

2.10e-0512853310GO:0031175
GeneOntologyBiologicalProcessneuron projection morphogenesis

TNIK ROCK1 SPAG9 KIF5B ITGA4 NEXN MINK1 MAPK8IP3

2.95e-05802338GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

TNIK ROCK1 SPAG9 KIF5B ITGA4 NEXN MINK1 MAPK8IP3

3.43e-05819338GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

TNIK ROCK1 SPAG9 KIF5B ITGA4 NEXN MINK1 MAPK8IP3

3.64e-05826338GO:0048858
GeneOntologyBiologicalProcessresponse to Thyroglobulin triiodothyronine

NCOA2 NCOA1

3.71e-056332GO:1904016
GeneOntologyBiologicalProcesspositive regulation of neuron differentiation

NCOA1 SPAG9 UPF3B MAPK8IP3

4.31e-05123334GO:0045666
GeneOntologyBiologicalProcessregulation of neuron differentiation

NCOA1 ROCK1 SPAG9 UPF3B MAPK8IP3

4.97e-05255335GO:0045664
GeneOntologyBiologicalProcessneuron development

TNIK ROCK1 SPAG9 UPF3B KIF5B ITGA4 HLA-C NEXN MINK1 MAPK8IP3

6.38e-0514633310GO:0048666
GeneOntologyBiologicalProcessmRNA metabolic process

NCOA2 NCOA1 PPARGC1A ROCK1 UPF3B TRMT6 NSRP1 RBM17

7.62e-05917338GO:0016071
GeneOntologyBiologicalProcesscell morphogenesis

TNIK SMARCA4 ROCK1 SPAG9 KIF5B ITGA4 NEXN MINK1 MAPK8IP3

7.71e-051194339GO:0000902
GeneOntologyBiologicalProcessanterograde axonal protein transport

KIF5B MAPK8IP3

8.87e-059332GO:0099641
GeneOntologyBiologicalProcessregulation of female receptivity

NCOA2 NCOA1

8.87e-059332GO:0045924
GeneOntologyBiologicalProcessaxo-dendritic protein transport

KIF5B MAPK8IP3

1.35e-0411332GO:0099640
GeneOntologyBiologicalProcessprotein localization to presynapse

KIF5B MAPK8IP3

1.35e-0411332GO:1905383
GeneOntologyBiologicalProcessfemale mating behavior

NCOA2 NCOA1

1.62e-0412332GO:0060180
GeneOntologyBiologicalProcesspositive regulation of adipose tissue development

NCOA2 NCOA1

2.23e-0414332GO:1904179
GeneOntologyBiologicalProcessadipose tissue development

NCOA2 NCOA1 PPARGC1A

2.72e-0479333GO:0060612
GeneOntologyBiologicalProcessmicrotubule-based protein transport

KIF5B MAPK8IP3

3.33e-0417332GO:0099118
GeneOntologyBiologicalProcessprotein transport along microtubule

KIF5B MAPK8IP3

3.33e-0417332GO:0098840
GeneOntologyBiologicalProcessregulation of adipose tissue development

NCOA2 NCOA1

5.11e-0421332GO:1904177
GeneOntologyBiologicalProcessregulation of cell migration

SMARCA4 PPARGC1A ROCK1 SPAG9 ITGA4 NEXN MINK1 MAPK8IP3

5.12e-041211338GO:0030334
GeneOntologyBiologicalProcesslysosome localization

SPAG9 KIF5B CPLX2

6.61e-04107333GO:0032418
GeneOntologyBiologicalProcessvacuolar localization

SPAG9 KIF5B CPLX2

6.61e-04107333GO:1990849
GeneOntologyBiologicalProcesspositive regulation of JNK cascade

TNIK MINK1 MAPK8IP3

6.61e-04107333GO:0046330
GeneOntologyBiologicalProcessregulation of cell motility

SMARCA4 PPARGC1A ROCK1 SPAG9 ITGA4 NEXN MINK1 MAPK8IP3

7.40e-041280338GO:2000145
GeneOntologyBiologicalProcessprotein localization to synapse

TNIK KIF5B MAPK8IP3

8.15e-04115333GO:0035418
GeneOntologyBiologicalProcessmicrovillus assembly

TNIK MINK1

9.14e-0428332GO:0030033
GeneOntologyBiologicalProcesslabyrinthine layer morphogenesis

NCOA1 ITGA4

9.14e-0428332GO:0060713
GeneOntologyBiologicalProcessperoxisome proliferator activated receptor signaling pathway

NCOA2 NCOA1

9.14e-0428332GO:0035357
GeneOntologyBiologicalProcessregulation of locomotion

SMARCA4 PPARGC1A ROCK1 SPAG9 ITGA4 NEXN MINK1 MAPK8IP3

9.37e-041327338GO:0040012
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

TNIK KIF5B ITGA4 NEXN MINK1 MAPK8IP3

1.07e-03748336GO:0048667
GeneOntologyCellularComponentnuclear chromosome

SMARCA4 SRCAP INCENP SMC1B ADD3

7.06e-05254365GO:0000228
GeneOntologyCellularComponentlateral element

INCENP SMC1B

4.84e-0419362GO:0000800
GeneOntologyCellularComponentcondensed nuclear chromosome

INCENP SMC1B ADD3

5.14e-0491363GO:0000794
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

SMARCA4 SRCAP RSF1

6.00e-0496363GO:0070603
GeneOntologyCellularComponentsomatodendritic compartment

NCOA2 PPARGC1A UPF3B KIF5B ITGA4 MINK1 MAPK8IP3 CPLX2

9.58e-041228368GO:0036477
GeneOntologyCellularComponentcentriolar satellite

SPAG9 UPF3B KIF5B

1.38e-03128363GO:0034451
GeneOntologyCellularComponentATPase complex

SMARCA4 SRCAP RSF1

1.41e-03129363GO:1904949
GeneOntologyCellularComponentcondensed chromosome

SMARCA4 INCENP SMC1B ADD3

1.86e-03307364GO:0000793
GeneOntologyCellularComponentsynaptonemal complex

INCENP SMC1B

2.85e-0346362GO:0000795
GeneOntologyCellularComponentsynaptonemal structure

INCENP SMC1B

2.85e-0346362GO:0099086
GeneOntologyCellularComponentdendrite

NCOA2 PPARGC1A KIF5B MINK1 MAPK8IP3 CPLX2

3.19e-03858366GO:0030425
GeneOntologyCellularComponentdendritic tree

NCOA2 PPARGC1A KIF5B MINK1 MAPK8IP3 CPLX2

3.23e-03860366GO:0097447
GeneOntologyCellularComponentaxon

KIF5B ITGA4 NEXN MINK1 MAPK8IP3 CPLX2

3.84e-03891366GO:0030424
DomainJIP_LZII

SPAG9 MAPK8IP3

3.41e-062352IPR032486
DomainJIP_LZII

SPAG9 MAPK8IP3

3.41e-062352PF16471
DomainDUF1518

NCOA2 NCOA1

1.02e-053352PF07469
DomainDUF1518

NCOA2 NCOA1

1.02e-053352IPR010011
DomainSrc1_rcpt_coact

NCOA2 NCOA1

1.02e-053352IPR008955
DomainNuclear_rcpt_coactivator

NCOA2 NCOA1

1.02e-053352IPR017426
DomainDUF1518

NCOA2 NCOA1

1.02e-053352SM01151
DomainNuc_rcpt_coact_Ncoa-typ

NCOA2 NCOA1

1.02e-053352IPR014920
DomainSRC-1

NCOA2 NCOA1

1.02e-053352IPR014935
DomainSRC-1

NCOA2 NCOA1

1.02e-053352PF08832
Domain-

NCOA2 NCOA1

1.02e-0533524.10.630.10
DomainNuc_rec_co-act

NCOA2 NCOA1

1.02e-053352PF08815
DomainHSA

SMARCA4 SRCAP

2.04e-054352SM00573
DomainJnk-SapK_ap_N

SPAG9 MAPK8IP3

2.04e-054352PF09744
DomainHSA

SMARCA4 SRCAP

2.04e-054352PS51204
DomainHSA_dom

SMARCA4 SRCAP

2.04e-054352IPR014012
DomainJNK/Rab-associated_protein-1_N

SPAG9 MAPK8IP3

2.04e-054352IPR019143
DomainHSA

SMARCA4 SRCAP

2.04e-054352PF07529
DomainRH2

SPAG9 MAPK8IP3

3.40e-055352PS51777
DomainRH1

SPAG9 MAPK8IP3

3.40e-055352PS51776
DomainNuc_rcpt_coact

NCOA2 NCOA1

5.09e-056352IPR009110
DomainCNH

TNIK MINK1

3.06e-0414352SM00036
DomainCNH

TNIK MINK1

3.53e-0415352PS50219
DomainCNH_dom

TNIK MINK1

3.53e-0415352IPR001180
DomainCNH

TNIK MINK1

3.53e-0415352PF00780
DomainPAS

NCOA2 NCOA1

9.96e-0425352PF00989
DomainPAS_fold

NCOA2 NCOA1

9.96e-0425352IPR013767
DomainSNF2_N

SMARCA4 SRCAP

1.63e-0332352PF00176
DomainSNF2_N

SMARCA4 SRCAP

1.63e-0332352IPR000330
DomainPAS

NCOA2 NCOA1

1.63e-0332352SM00091
DomainPAS

NCOA2 NCOA1

1.84e-0334352IPR000014
DomainPAS

NCOA2 NCOA1

1.84e-0334352PS50112
Domain-

PPARGC1A UPF3B RBM17

1.06e-022443533.30.70.330
DomainNucleotide-bd_a/b_plait

PPARGC1A UPF3B RBM17

1.23e-02258353IPR012677
PathwayPID_ERB_GENOMIC_PATHWAY

NCOA2 SMARCA4 NCOA1

3.89e-0615303M119
PathwayPID_BETA_CATENIN_NUC_PATHWAY

TNIK NCOA2 SMARCA4 INCENP

2.36e-0580304M223
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

NCOA2 NCOA1 PPARGC1A

3.76e-0531303M39476
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

NCOA2 NCOA1 PPARGC1A

4.14e-0532303M39567
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

NCOA2 NCOA1 PPARGC1A

1.09e-0444303M27295
PathwayBIOCARTA_PPARG_PATHWAY

NCOA1 PPARGC1A

1.22e-048302M22058
PathwayREACTOME_HEME_SIGNALING

NCOA2 NCOA1 PPARGC1A

1.50e-0449303M41832
PathwayPID_ARF6_TRAFFICKING_PATHWAY

SPAG9 ITGA4 MAPK8IP3

1.50e-0449303M67
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

NCOA2 NCOA1 PPARGC1A

2.12e-0455303M27145
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

NCOA2 NCOA1

2.38e-0411302M47503
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

NCOA2 NCOA1

3.92e-0414302M27074
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

NCOA2 NCOA1

3.92e-0414302MM14748
PathwayREACTOME_CIRCADIAN_CLOCK

NCOA2 NCOA1 PPARGC1A

4.32e-0470303M938
PathwayREACTOME_SUMOYLATION

NCOA2 NCOA1 PPARGC1A INCENP

6.53e-04189304M27214
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

NCOA2 NCOA1

6.56e-0418302M4862
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

NCOA2 NCOA1

6.56e-0418302MM15034
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA2 NCOA1

6.56e-0418302M26942
PathwayPID_REG_GR_PATHWAY

NCOA2 SMARCA4 NCOA1

6.88e-0482303M115
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

NCOA2 NCOA1

7.32e-0419302MM14612
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

NCOA2 NCOA1 PPARGC1A

7.38e-0484303M1008
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

NCOA2 NCOA1 ROCK1

9.31e-0491303M39700
PathwayWP_HIPPOYAP_SIGNALING

TNIK MINK1

9.85e-0422302M39821
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

NCOA2 NCOA1

1.08e-0323302M1926
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

NCOA2 NCOA1

1.08e-0323302MM14741
PathwayREACTOME_MITOCHONDRIAL_BIOGENESIS

NCOA2 NCOA1 PPARGC1A

1.09e-0396303M26973
PathwayBIOCARTA_VDR_PATHWAY

SMARCA4 NCOA1

1.17e-0324302M13404
PathwayREACTOME_ENDOGENOUS_STEROLS

NCOA2 NCOA1

1.27e-0325302M11184
PathwayREACTOME_ENDOGENOUS_STEROLS

NCOA2 NCOA1

1.49e-0327302MM14844
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

NCOA2 NCOA1

1.49e-0327302M26943
PathwayREACTOME_ADIPOGENESIS

NCOA2 NCOA1 PPARGC1A

1.61e-03110303M48259
PathwayPID_RETINOIC_ACID_PATHWAY

NCOA2 NCOA1

1.84e-0330302M207
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_BROWN_AND_BEIGE_ADIPOCYTE_DIFFERENTIATION

NCOA1 PPARGC1A

1.96e-0331302M48258
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

NCOA2 NCOA1 PPARGC1A

1.97e-03118303M27316
PathwayREACTOME_RHO_GTPASE_EFFECTORS

NCOA2 ROCK1 KIF5B INCENP

2.04e-03257304MM14755
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

NCOA2 NCOA1

2.22e-0333302M5967
PathwayPID_NCADHERIN_PATHWAY

ROCK1 KIF5B

2.22e-0333302M266
PathwayPID_INTEGRIN_A4B1_PATHWAY

ITGA4 ADAM28

2.22e-0333302M277
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

NCOA2 NCOA1

2.22e-0333302MM14737
PathwayWP_ADIPOGENESIS

NCOA2 NCOA1 PPARGC1A

2.65e-03131303M39505
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

TNIK MINK1

2.78e-0337302MM14899
PathwayWP_ADIPOGENESIS_GENES

NCOA2 NCOA1 PPARGC1A

3.01e-03137303MM15970
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

NCOA2 NCOA1

3.58e-0342302M27172
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

NCOA2 NCOA1

3.92e-0344302M499
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

NCOA2 NCOA1

4.09e-0345302MM14751
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CEP350 NCOA2 ROCK1 SPAG9 UPF3B KIF5B CCDC59 SRCAP INCENP RSF1

7.39e-10645361025281560
Pubmed

Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator-activated receptor {gamma} agonists in colon cancer cells.

NCOA2 NCOA1 PPARGC1A

4.07e-09436317513608
Pubmed

Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.

NCOA2 NCOA1 PPARGC1A

1.02e-08536318798693
Pubmed

A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.

NCOA2 NCOA1 PPARGC1A

1.02e-08536315026545
Pubmed

A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.

NCOA2 NCOA1 PPARGC1A

2.03e-08636316373399
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TNIK SMARCA4 SPAG9 UPF3B KIF5B SRCAP NSRP1 ADD3 RSF1 RBM17

2.51e-08934361033916271
Pubmed

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.

NCOA2 SMARCA4 NCOA1

3.55e-0873639590696
Pubmed

Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.

NCOA2 NCOA1 PPARGC1A

5.68e-08836323178929
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CEP350 TNIK SMARCA4 UPF3B TRMT6 KIF5B CCDC59 CLPB HLA-C ADD3 RBM17

8.31e-081371361136244648
Pubmed

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.

NCOA2 NCOA1 PPARGC1A

1.67e-071136336613751
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

NCOA2 SMARCA4 NCOA1

6.86e-071736319183483
Pubmed

Structural characterization of the RH1-LZI tandem of JIP3/4 highlights RH1 domains as a cytoskeletal motor-binding motif.

SPAG9 MAPK8IP3

1.04e-06236231690808
Pubmed

The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1.

ITGA4 ADAM28

1.04e-06236211724793
Pubmed

JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport.

KIF5B MAPK8IP3

1.04e-06236235829703
Pubmed

SRC-1 and TIF2 control energy balance between white and brown adipose tissues.

NCOA2 NCOA1

1.04e-06236212507421
Pubmed

Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons.

SPAG9 MAPK8IP3

1.04e-06236233788575
Pubmed

Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction.

NCOA2 NCOA1

1.04e-06236215070739
Pubmed

Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.

NCOA2 NCOA1

1.04e-06236211897715
Pubmed

Microenvironmental Interaction Between Hypoxia and Endothelial Cells Controls the Migration Ability of Placenta-Derived Mesenchymal Stem Cells via α4 Integrin and Rho Signaling.

ROCK1 ITGA4

1.04e-06236226448639
Pubmed

Tumor necrosis factor-alpha suppresses the expression of steroid receptor coactivator-1 and -2: a possible mechanism contributing to changes in steroid hormone responsiveness.

NCOA2 NCOA1

1.04e-06236215231721
Pubmed

Distinct steady-state nuclear receptor coregulator complexes exist in vivo.

NCOA2 NCOA1

1.04e-0623629751728
Pubmed

Ncoa2 Promotes CD8+ T cell-Mediated Antitumor Immunity by Stimulating T-cell Activation via Upregulation of PGC-1α Critical for Mitochondrial Function.

NCOA2 PPARGC1A

1.04e-06236237540802
Pubmed

Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis.

NCOA2 NCOA1

1.04e-06236225148457
Pubmed

Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3).

ROCK1 SPAG9 MAPK8IP3

1.15e-062036312897243
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA2 NCOA1 PPARGC1A

1.34e-062136319596656
Pubmed

Negative modulation of androgen receptor transcriptional activity by Daxx.

NCOA2 NCOA1 PPARGC1A

1.55e-062236315572661
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

TNIK ROCK1 ITGA4 HLA-C ADD3 MINK1

2.31e-0637736638117590
Pubmed

The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.

NCOA2 NCOA1

3.12e-06336221035760
Pubmed

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.

NCOA2 NCOA1

3.12e-06336224550004
Pubmed

Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.

NCOA2 NCOA1

3.12e-06336221059860
Pubmed

RORgammat recruits steroid receptor coactivators to ensure thymocyte survival.

NCOA2 NCOA1

3.12e-06336216148126
Pubmed

Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse.

NCOA2 NCOA1

3.12e-06336216914740
Pubmed

Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.

NCOA2 NCOA1

3.12e-06336216675958
Pubmed

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene.

NCOA2 NCOA1

3.12e-0633629506940
Pubmed

Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers.

NCOA2 NCOA1

3.12e-06336228390937
Pubmed

SNF2-related CBP activator protein (SRCAP) functions as a coactivator of steroid receptor-mediated transcription through synergistic interactions with CARM-1 and GRIP-1.

NCOA2 SRCAP

3.12e-06336214500758
Pubmed

The role of SRC1 and SRC2 in steroid-induced SDF1 expression in normal and ectopic endometrium.

NCOA2 NCOA1

3.12e-06336224586072
Pubmed

Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human.

NCOA2 NCOA1

3.12e-06336217045797
Pubmed

Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.

NCOA2 NCOA1

3.12e-06336223927929
Pubmed

The scaffold protein JIP3 functions as a downstream effector of the small GTPase ARF6 to regulate neurite morphogenesis of cortical neurons.

SPAG9 MAPK8IP3

3.12e-06336220493856
Pubmed

JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration.

SPAG9 MAPK8IP3

3.12e-06336225571974
Pubmed

Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage.

ROCK1 MAPK8IP3

3.12e-06336219036714
Pubmed

Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts.

NCOA2 NCOA1

3.12e-06336233574497
Pubmed

Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder.

NCOA2 NCOA1

3.12e-06336218845648
Pubmed

The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

NCOA2 NCOA1

3.12e-06336212138202
Pubmed

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

TNIK MINK1

3.12e-06336218930710
Pubmed

Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.

NCOA2 NCOA1

3.12e-06336214757047
Pubmed

Nuclear orphan receptor NR4A2 modulates fatty acid oxidation pathways in colorectal cancer.

NCOA1 PPARGC1A

3.12e-06336221757690
Pubmed

Structure and chromosomal locations of mouse steroid receptor coactivator gene family.

NCOA2 NCOA1

3.12e-06336210501088
Pubmed

Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators.

NCOA2 NCOA1

3.12e-06336212114525
Pubmed

JSAP1 and JLP are required for ARF6 localization to the midbody in cytokinesis.

SPAG9 MAPK8IP3

3.12e-06336225130574
Pubmed

Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice.

NCOA2 NCOA1

3.12e-06336215983373
Pubmed

The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.

NCOA2 NCOA1

3.12e-06336216423883
Pubmed

Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice.

SPAG9 MAPK8IP3

3.12e-06336226320416
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TNIK ROCK1 ITGA4 HLA-C ADD3 MINK1

4.35e-0642136636976175
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

SMARCA4 UPF3B KIF5B CCDC59 HLA-C NEXN NSRP1 RBM17

4.58e-0694936836574265
Pubmed

miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.

NCOA2 NCOA1

6.24e-06436226066330
Pubmed

Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation.

NCOA2 NCOA1

6.24e-06436211818499
Pubmed

Multiple signal input and output domains of the 160-kilodalton nuclear receptor coactivator proteins.

NCOA2 NCOA1

6.24e-06436210454563
Pubmed

P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.

NCOA2 NCOA1

6.24e-06436218267973
Pubmed

Selective recruitment of p160 coactivators on glucocorticoid-regulated promoters in Schwann cells.

NCOA2 NCOA1

6.24e-06436215331759
Pubmed

Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex.

NCOA2 NCOA1

6.24e-06436212024042
Pubmed

Characterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cells.

NCOA2 PPARGC1A

6.24e-06436219462000
Pubmed

Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein.

SPAG9 MAPK8IP3

6.24e-06436211106729
Pubmed

Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.

NCOA2 NCOA1

6.24e-06436219095746
Pubmed

Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha.

NCOA2 NCOA1

6.24e-06436210594042
Pubmed

Transcriptional synergism on the pS2 gene promoter between a p160 coactivator and estrogen receptor-alpha depends on the coactivator subtype, the type of estrogen response element, and the promoter context.

NCOA2 NCOA1

6.24e-06436212403846
Pubmed

Deoxyribonucleic acid response element-dependent regulation of transcription by orphan nuclear receptor estrogen receptor-related receptor gamma.

NCOA2 PPARGC1A

6.24e-06436214645497
Pubmed

Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.

NCOA2 NCOA1

6.24e-06436222560224
Pubmed

A simple method to screen ligands of peroxisome proliferator-activated receptor delta.

NCOA2 NCOA1

6.24e-06436216930961
Pubmed

Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.

NCOA2 NCOA1

6.24e-06436226267537
Pubmed

Isoform-specific transcriptional regulation by thyroid hormone receptors: hormone-independent activation operates through a steroid receptor mode of co-activator interaction.

NCOA2 NCOA1

6.24e-06436211435616
Pubmed

Activation of PPARgamma coactivator-1 through transcription factor docking.

NCOA1 PPARGC1A

6.24e-06436210558993
Pubmed

Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.

NCOA2 NCOA1

6.24e-06436215563453
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 SMARCA4 NCOA1 TNRC18 RBM17

8.12e-0626836533640491
Pubmed

LZTR1 is a regulator of RAS ubiquitination and signaling.

TNIK ROCK1 ADD3 MINK1

9.12e-0612736430442766
Pubmed

Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene.

NCOA2 NCOA1

1.04e-05536210652338
Pubmed

Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members.

NCOA2 NCOA1

1.04e-05536217950690
Pubmed

SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.

NCOA2 NCOA1

1.04e-05536217476305
Pubmed

Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility.

KIF5B MAPK8IP3

1.04e-05536221750526
Pubmed

Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function.

NCOA2 NCOA1

1.04e-05536217854779
Pubmed

Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes.

NCOA2 NCOA1

1.04e-05536218511550
Pubmed

Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription.

NCOA2 NCOA1

1.04e-05536211514567
Pubmed

Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members.

NCOA2 NCOA1

1.04e-05536211014206
Pubmed

Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.

NCOA2 NCOA1

1.04e-05536214993927
Pubmed

BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation.

SMARCA4 NCOA1

1.04e-05536211003650
Pubmed

Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.

NCOA2 NCOA1

1.04e-05536212714702
Pubmed

Regulation of transcription by a protein methyltransferase.

NCOA2 NCOA1

1.04e-05536210381882
Pubmed

Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1.

NCOA2 NCOA1

1.04e-05536215721253
Pubmed

SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells.

NCOA2 NCOA1

1.04e-05536212514218
Pubmed

Ligands specify coactivator nuclear receptor (NR) box affinity for estrogen receptor subtypes.

NCOA2 NCOA1

1.04e-05536211376110
Pubmed

Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells.

NCOA2 NCOA1

1.04e-05536212554772
Pubmed

RBCK1, an E3 ubiquitin ligase, interacts with and ubiquinates the human pregnane X receptor.

NCOA2 NCOA1

1.04e-05536223160820
Pubmed

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

NCOA2 NCOA1

1.04e-0553629812974
Pubmed

Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.

NCOA1 PPARGC1A

1.04e-05536216455805
Pubmed

The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding.

NCOA2 NCOA1

1.04e-05536210757795
Pubmed

Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells.

NCOA2 SMARCA4

1.04e-05536214966121
Pubmed

2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.

NCOA2 NCOA1

1.04e-05536212796488
Pubmed

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.

NCOA1 PPARGC1A

1.04e-05536212754525
Pubmed

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance.

NCOA1 PPARGC1A

1.04e-05536217011503
InteractionH2BC8 interactions

SMARCA4 UPF3B TRMT6 CCDC59 ITGA4 SRCAP INCENP NSRP1 RSF1

5.65e-07576369int:H2BC8
InteractionPPARD interactions

CEP350 NCOA2 NCOA1 PPARGC1A TRMT6

1.98e-06117365int:PPARD
InteractionEP300 interactions

NCOA2 SMARCA4 NCOA1 PPARGC1A ROCK1 SPAG9 KIF5B SRCAP CLPB MAPK8IP3 RSF1 RBM17

3.17e-0614013612int:EP300
InteractionTERF2IP interactions

NCOA2 SMARCA4 ZBTB2 TRMT6 SRCAP INCENP NSRP1 RSF1

4.63e-06552368int:TERF2IP
InteractionNAA40 interactions

TNIK SMARCA4 SPAG9 UPF3B KIF5B SRCAP NSRP1 ADD3 RSF1 RBM17

5.55e-069783610int:NAA40
InteractionARF6 interactions

TNIK ROCK1 SPAG9 UPF3B ITGA4 ATP8B2 ADD3 MINK1

7.00e-06584368int:ARF6
InteractionNRIP1 interactions

NCOA2 NCOA1 PPARGC1A CLPB MAPK8IP3

1.23e-05170365int:NRIP1
InteractionSOX7 interactions

NCOA2 SMARCA4 NCOA1 TNRC18

1.36e-0582364int:SOX7
InteractionNR4A2 interactions

SMARCA4 NCOA1 PPARGC1A

1.49e-0527363int:NR4A2
InteractionSTAT6 interactions

NCOA2 SMARCA4 NCOA1 ZBTB2

1.72e-0587364int:STAT6
InteractionRAP2A interactions

TNIK NCOA1 TRMT6 MINK1

2.05e-0591364int:RAP2A
InteractionPPARA interactions

CEP350 NCOA2 NCOA1 PPARGC1A

2.14e-0592364int:PPARA
InteractionCARM1 interactions

TNIK NCOA2 SMARCA4 NCOA1 KIF5B SRCAP

2.18e-05325366int:CARM1
InteractionACTC1 interactions

SMARCA4 ITGA4 SRCAP NEXN ATP8B2 NSRP1 ADD3 RBM17

2.44e-05694368int:ACTC1
InteractionNR5A2 interactions

NCOA2 NCOA1 PPARGC1A

5.33e-0541363int:NR5A2
InteractionOGA interactions

PPARGC1A SPAG9 KIF5B CLPB

8.05e-05129364int:OGA
InteractionNR1I3 interactions

NCOA2 NCOA1 PPARGC1A

8.57e-0548363int:NR1I3
InteractionNR1I2 interactions

NCOA2 NCOA1 PPARGC1A

8.57e-0548363int:NR1I2
InteractionSMCO1 interactions

SPAG9 MAPK8IP3

8.63e-058362int:SMCO1
InteractionAHR interactions

NCOA2 SMARCA4 NCOA1 ROCK1

8.80e-05132364int:AHR
InteractionWWTR1 interactions

NCOA2 SMARCA4 SPAG9 KIF5B SRCAP ADD3

9.30e-05422366int:WWTR1
InteractionNCOA2 interactions

NCOA2 NCOA1 KIF5B SRCAP

1.14e-04141364int:NCOA2
InteractionHNF4A interactions

NCOA2 SMARCA4 NCOA1 PPARGC1A SRCAP

1.22e-04275365int:HNF4A
InteractionNCOA1 interactions

NCOA2 SMARCA4 NCOA1 PPARGC1A

1.30e-04146364int:NCOA1
InteractionNR1H3 interactions

CEP350 NCOA1 PPARGC1A

1.51e-0458363int:NR1H3
InteractionH3C1 interactions

SMARCA4 SPAG9 TNRC18 ITGA4 SRCAP INCENP NSRP1 RSF1

1.53e-04901368int:H3C1
InteractionCIT interactions

TNIK SMARCA4 UPF3B ITGA4 CLPB INCENP HLA-C NEXN RSF1 RBM17

1.62e-0414503610int:CIT
InteractionMCAM interactions

TNIK ROCK1 ITGA4 HLA-C ADD3 MINK1

1.64e-04468366int:MCAM
InteractionNR5A1 interactions

NCOA2 NCOA1 PPARGC1A

1.67e-0460363int:NR5A1
InteractionPPARG interactions

CEP350 NCOA2 SMARCA4 NCOA1 PPARGC1A

2.03e-04307365int:PPARG
InteractionNFKB1 interactions

NCOA1 PPARGC1A SPAG9 KIF5B RSF1

2.03e-04307365int:NFKB1
InteractionH3C3 interactions

SMARCA4 TRMT6 ITGA4 SRCAP INCENP RSF1

2.22e-04495366int:H3C3
InteractionRXRA interactions

NCOA2 SMARCA4 NCOA1 PPARGC1A

2.28e-04169364int:RXRA
InteractionESRRA interactions

NCOA2 NCOA1 PPARGC1A

2.32e-0467363int:ESRRA
InteractionSART1 interactions

TNIK SPAG9 UPF3B NSRP1 RBM17

2.36e-04317365int:SART1
InteractionNR1H2 interactions

NCOA2 SMARCA4 NCOA1

2.42e-0468363int:NR1H2
InteractionKAT6A interactions

CEP350 SMARCA4 UPF3B ZBTB2 RSF1 RBM17

2.61e-04510366int:KAT6A
InteractionWDHD1 interactions

NCOA2 NCOA1 SPAG9 UPF3B

2.72e-04177364int:WDHD1
InteractionH3-3A interactions

SMARCA4 SPAG9 TRMT6 ITGA4 SRCAP INCENP RSF1

3.10e-04749367int:H3-3A
InteractionMYOD1 interactions

NCOA2 SMARCA4 NCOA1 PPARGC1A

3.85e-04194364int:MYOD1
InteractionANK3 interactions

TNIK SPAG9 NEXN MAPK8IP3

4.41e-04201364int:ANK3
InteractionMED17 interactions

SMARCA4 PPARGC1A ROCK1 SRCAP

4.49e-04202364int:MED17
InteractionGALNT13 interactions

TNIK MINK1

4.66e-0418362int:GALNT13
InteractionADAM28 interactions

ITGA4 ADAM28

4.66e-0418362int:ADAM28
InteractionCREBBP interactions

NCOA2 SMARCA4 NCOA1 PPARGC1A ZBTB2 SRCAP

6.13e-04599366int:CREBBP
InteractionRHOB interactions

TNIK ROCK1 UPF3B CCDC59 HLA-C ADD3 MINK1

6.17e-04840367int:RHOB
InteractionH3C6 interactions

SMARCA4 ITGA4 NSRP1 RBM17

6.84e-04226364int:H3C6
InteractionHDLBP interactions

TNIK SMARCA4 UPF3B KIF5B CCDC59 ADD3 RBM17

6.86e-04855367int:HDLBP
InteractionKIF5A interactions

TNIK NCOA2 KIF5B

7.09e-0498363int:KIF5A
Cytoband22q13.31

PKDREJ SMC1B

6.05e-044636222q13.31
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA2 NCOA1

1.90e-0417222486
GeneFamilyBasic helix-loop-helix proteins

NCOA2 NCOA1

7.83e-03110222420
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CEP350 PPARGC1A KIF5B CCDC59 NSRP1 ADD3 RSF1 RBM17

2.40e-06656368M18979
CoexpressionSTARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP

ROCK1 TNRC18 MINK1 RSF1 CPLX2

8.83e-06206365M2817
CoexpressionSTARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP

ROCK1 TNRC18 MINK1 RSF1 CPLX2

9.26e-06208365MM581
CoexpressionFEVR_CTNNB1_TARGETS_DN

ROCK1 TRMT6 KIF5B INCENP ADD3 RSF1

9.95e-05555366M2343
CoexpressionGSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN

PSTPIP1 ITGA4 ADD3 MAPK8IP3

1.48e-04196364M6111
CoexpressionGSE40273_XBP1_KO_VS_WT_TREG_DN

CEP350 ITGA4 DENND11 ATP8B2

1.57e-04199364M9124
CoexpressionGSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP

ROCK1 UPF3B DENND11 RSF1

1.60e-04200364M5069
CoexpressionGSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_DN

CEP350 NCOA1 SRCAP ATP8B2

1.60e-04200364M3965
CoexpressionGSE17721_POLYIC_VS_CPG_16H_BMDC_UP

NCOA1 TNRC18 PKDREJ ADD3

1.60e-04200364M3950
CoexpressionGSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_DN

ROCK1 HLA-C ADD3 RSF1

1.60e-04200364M7444
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1

PPARGC1A ROCK1 KIF5B HLA-C RSF1 RBM17

4.45e-06259366Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

ROCK1 ZBTB2 KIF5B INCENP NSRP1 RSF1 RBM17

1.18e-05469367Facebase_RNAseq_e8.5_Floor Plate_2500_K1
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

CEP350 TNIK NCOA2 KIF5B ADD3

3.89e-0718636503db813598b67b1e08f759758a1c2023396921fa
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CEP350 UPF3B NEXN NSRP1 RSF1

5.16e-071973650fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK ITGA4 EXD1 ATP8B2

6.61e-06151364d19fc363ba1d7ff77e0adcaacafa4c64e1143f40
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 ITGA4 RSF1 CPLX2

1.47e-051853647adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellsystemic_lupus_erythematosus-treated|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ROCK1 ITGA4 HLA-C ADD3

1.92e-051983648165ff735095c52994fb5057d89be93cc378b7da
ToppCellCOVID-CD4|COVID / Condition, Cell_class and T cell subcluster

TNIK ITGA4 ATP8B2 ADD3

1.92e-051983643b72d3fa96f8cda528c483afdff391385113080d
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

CEP350 ROCK1 NSRP1 RSF1

1.96e-05199364c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

CEP350 ROCK1 NSRP1 RSF1

1.96e-05199364fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CEP350 ROCK1 SPAG9 ITGA4

2.00e-0520036412f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA2012 EXD1 SMC1B

2.08e-041433634a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA2012 EXD1 SMC1B

2.08e-0414336365328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA4 KIAA2012 CPLX2

2.21e-04146363b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCellLA-15._Ventricular_Cardiomyocyte_III|LA / Chamber and Cluster_Paper

PPARGC1A NEXN CPLX2

2.25e-041473638970eb6b82589f39439c61a57d999661ec8342de
ToppCellAdult-Immune-dendritic_cell-D122|Adult / Lineage, Cell type, age group and donor

PSTPIP1 ITGA4 ADAM28

2.58e-0415436364a4686586d08b1e9632dde917b472ac660de2d3
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNIK ITGA4 DENND11

2.89e-041603636b0faaa371650563f585722f5b2fb319e124ec38
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

SPAG9 DENND11 RBM17

2.94e-04161363347edb0de10850b7d16c40945751033289289c9b
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo|Lung / Manually curated celltypes from each tissue

ITGA4 PKDREJ SMC1B

2.94e-04161363a1f10e04836848b1deaf295fae033f54d1572fcd
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSTPIP1 INCENP DENND11

3.34e-04168363a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA4 ATP8B2 MINK1

3.34e-04168363e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCHH NEXN CPLX2

3.39e-0416936316c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-club_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCHH EXD1 ADAM28

3.45e-041703636de3778e8257c3330db0780c59238ca501fe5059
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-club_cell-club_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCHH EXD1 ADAM28

3.45e-0417036360887da674ef1a735bad618235608312d8de63d3
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TNIK ITGA4 ADAM28

3.57e-041723633a76cfb2832790144a6da6406469ead0767916b5
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP NEXN SMC1B

3.57e-04172363c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 ADAM28

3.63e-0417336373f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCellImmune_cells-pro-B|World / Lineage and Cell class

SMARCA4 PPARGC1A CPLX2

3.70e-04174363e173adbf5789dfa20f3cbc668efde5f0992ac219
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

NCOA2 ITGA4 NEXN

3.76e-041753632812ac2ef41d245db544697fb6da1883361c96e8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 HLA-C

3.76e-04175363da92eb8af0c7c65fed4a1d960708240f35dd997d
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP NEXN SMC1B

3.76e-04175363a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 HLA-C

3.76e-041753632f43883d7c89f09b0579a390a7431f1f9b832582
ToppCellDendritic_Cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PSTPIP1 ITGA4 ADAM28

3.88e-04177363d2cd081bdda0eba9f6f6473c4d3939e4bee3440e
ToppCellfacs-Lung-nan-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCHH EXD1 ADAM28

3.88e-04177363b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCellfacs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCHH EXD1 ADAM28

3.88e-04177363e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCellCTRL-Lymphoid-T_cell_&_NK_cell|CTRL / Disease state, Lineage and Cell class

PSTPIP1 ITGA4 ATP8B2

3.88e-04177363e73d8e78a96b63e27a8a7694c62b3c44ec7ecfe6
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

SPAG9 DENND11 RBM17

3.88e-04177363e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSTPIP1 ITGA4 HLA-C

3.95e-04178363a96941fef62c2f4533c557ef825ae3265f8f52db
ToppCellnormal_Lung-Myeloid_cells-CD163+CD14+_DCs|normal_Lung / Location, Cell class and cell subclass

TCHH ADAM28 SMC1B

3.95e-04178363b6dacaad09bf4384d0d4c926fbf769e74a8ec9a9
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCHH NEXN CPLX2

4.01e-04179363948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCellsevere-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TNIK DENND11 ATP8B2

4.08e-04180363ac03812b1409435c55d323a7516deeac82bd3509
ToppCellRA-17._Lymphocyte|RA / Chamber and Cluster_Paper

ITGA4 HLA-C CPLX2

4.21e-04182363257a7847917b6ea1d60608183d90300bfd028758
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 ITGA4 CPLX2

4.21e-04182363f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellDendritic_Cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

PSTPIP1 ITGA4 ADAM28

4.28e-04183363499da89b4abe7b746e703cd1e5c56f9b1d97ac3c
ToppCellmoderate-Epithelial-IRC-IFNG_responsive_cell|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

HLA-C PKDREJ NEXN

4.28e-041833634ba879552e2101a341f3224826d364ac64c72260
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK ITGA4 ADD3

4.28e-04183363317b756378a9efd8ecb754acf7273f83f996e106
ToppCellRA-17._Lymphocyte|World / Chamber and Cluster_Paper

ITGA4 HLA-C CPLX2

4.28e-041833636397f684a50346fc42cccb5afbe10350f4b2d9b0
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK ITGA4 ADAM28

4.35e-04184363ce31684772e47a294155f368e50b49753f7c8e87
ToppCellCOVID-CD4-naive_CD4|COVID / Condition, Cell_class and T cell subcluster

TNIK ITGA4 ADD3

4.35e-0418436300db55970d336a301035efe43a4ab4db62627f38
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 ITGA4 RSF1

4.35e-041843631154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA4 ATP8B2 CPLX2

4.42e-041853632a8104f610fa5ce618f8105521616722462a0d42
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA4 INCENP CPLX2

4.49e-04186363ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA4 INCENP CPLX2

4.49e-041863633993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCelldroplet-Tongue-nan-24m-Epithelial-parabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCHH PSTPIP1 ADAM28

4.49e-0418636318c06041c6c8a0ebac17b3c8aaebd67e652d315a
ToppCellHealthy/Control-CD4+_CTL|World / Disease group and Cell class

TNIK ITGA4 HLA-C

4.56e-04187363d54d3214d77a9469e94a16c00a80626fd4953e2b
ToppCellCF-Lymphoid-T_cell_&_NK_cell|Lymphoid / Disease state, Lineage and Cell class

TNIK PSTPIP1 ITGA4

4.63e-0418836315057036b46c9df621ec4955aa94ca3036245d45
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK1 SPAG9 KIF5B

4.63e-04188363d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

TNIK PPARGC1A NEXN

4.63e-041883630758b474457efa36488e0195f7357100f4b6a090
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ITGA4 ATP8B2 ADAM28

4.63e-04188363567b08514d9d84cbb40f9b7a679eec304f023428
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK PSTPIP1 ITGA4

4.70e-04189363d05e043d0874b8563b9f5514f6c884b35c603e3a
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

PPARGC1A NEXN MAPK8IP3

4.70e-041893630a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMARCA4 ITGA4 ADD3

4.78e-04190363d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

NCOA2 ITGA4 ADD3

4.78e-04190363ed978cd5d9da87b49878a330e362762c487f849f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK ITGA4 ADD3

4.78e-0419036391ba66d4b56c59523485b17738e93f14bb00afa4
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

PPARGC1A NEXN MAPK8IP3

4.78e-0419036393c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

TNIK PPARGC1A NEXN

4.78e-04190363de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSTPIP1 ITGA4 HLA-C

4.78e-04190363ce049630ed69d31f00acbc1b5b0896efc592121f
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_CD8+_T|metastatic_Brain / Location, Cell class and cell subclass

PSTPIP1 ITGA4 HLA-C

4.85e-04191363b98367fdb56ccb335d61035e69cd43c61a7fa816
ToppCellNS-control-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PSTPIP1 ITGA4 ATP8B2

4.85e-0419136327f2151da2f41015a979499f274ab1284a36189f
ToppCellcontrol-Lymphoid-CTL|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PSTPIP1 ITGA4 ATP8B2

4.85e-041913638df23473e24cfa51c09986102ddd391ed0f0b9cc
ToppCellNS-critical-d_07-13-Lymphoid-Treg|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TNIK ITGA4 ATP8B2

4.92e-04192363cd34defac6565d34db507918e791b09c79f7d1f8
ToppCellNS-moderate-d_07-13-Lymphoid-CTL|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PSTPIP1 ITGA4 ATP8B2

4.92e-04192363ab2c3d829f5cbf4eb386babcfdf851222a2a88e8
ToppCellASK428-Immune-T_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ITGA4 HLA-C ATP8B2

4.92e-04192363121cb8c61002f20e1d287b8a7e67a30bb163e74a
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

TNIK PPARGC1A NEXN

4.92e-04192363ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSTPIP1 ITGA4 HLA-C

4.92e-04192363edb0f4fff3a9d7af5e71d3a282f358cf04ca1435
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA4 INCENP CPLX2

5.00e-041933639c2f58b4c89dc084a1a6e53952ea793e87a96660
ToppCellmoderate-Lymphoid-CTL|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PSTPIP1 ITGA4 ATP8B2

5.00e-041933633fce0807631811da1cff5ca9db23ff1ad36020e7
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

TNIK PPARGC1A NEXN

5.00e-04193363dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellASK428-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

ITGA4 ATP8B2 ADD3

5.00e-04193363bca9bf941193feea8ed56735041513185c165135
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA4 INCENP CPLX2

5.00e-04193363db881cc129b45031fd84d052768cef53508de196
ToppCellT_cells-Central_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TNIK ATP8B2 ADD3

5.00e-04193363725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 ADAM28

5.08e-0419436396f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCellNS-moderate-d_16-33-Lymphoid-CTL|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PSTPIP1 ITGA4 ATP8B2

5.08e-041943636b2bb3dd11fd53fa9ab4d66c18b0714f96f99288
ToppCellHealthy_donor-CD8+_Tem|Healthy_donor / disease group, cell group and cell class (v2)

TNIK ITGA4 HLA-C

5.08e-04194363bf2e889de60b2b452a41f4d59a0f2a1865f07184
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSTPIP1 ITGA4 HLA-C

5.08e-041943639344556b375fd9267652cdca57b2cbd50a878a1e
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSTPIP1 ITGA4 HLA-C

5.08e-0419436313c3674d601c8a7355ce869de1af6401938c0037
ToppCellBronchial_Brush-Immune-Dendritic_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

SPAG9 ITGA4 ADAM28

5.08e-04194363dbcc00940538efc0f89f074dbe822c50efa5ad8e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 ADAM28

5.08e-041943630866ab6792cee274a71991d5c37a37f574ff446e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 ADAM28

5.15e-0419536391a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

TNIK PPARGC1A NEXN

5.15e-04195363f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK ITGA4 ADD3

5.15e-04195363e06ff785c5542c86c335d956799e03f7ae8345a4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 HLA-C

5.15e-04195363deadfbc25e922c967b96bdbed4e7b16ff77ee132
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSTPIP1 ITGA4 HLA-C

5.15e-041953636774c9f7fa54045aaa35fbd0695e43748da2b293
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 ADAM28

5.15e-04195363ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 ADAM28

5.15e-041953632d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSTPIP1 ITGA4 HLA-C

5.15e-04195363073593a7f668512d1fbbb49efb0c20b736c79ff8
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TNIK ATP8B2 ADD3

5.15e-041953634bdedd924564a260841a9153604026b57487c83d
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TNIK ATP8B2 ADD3

5.15e-0419536322191d361af136942508f1553ff41a626ed982ad
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PSTPIP1 ITGA4 ADAM28

5.15e-0419536309df40ff9b493170861b3f6e57a942a834655b5c
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA4 INCENP CPLX2

5.15e-041953635749ea833be84e262e3d0a4fe1a9a373f0ef545f
ToppCellHealthy/Control-CD8+_Tem|Healthy/Control / Disease group and Cell class

TNIK ITGA4 HLA-C

5.15e-04195363f4955c176c4918052dc151c5e5249223ec428272
ToppCellCV-Moderate-6|Moderate / Virus stimulation, Condition and Cluster

CEP350 NCOA1 ROCK1

5.15e-041953632b8a72d7e755b9655c7a496000d10ff06e50862b
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

CEP350 ROCK1 ITGA4

1.48e-0449233GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
ComputationalNeighborhood of MAP4K4

CEP350 TNIK SPAG9 MAPK8IP3

4.42e-04172234GCM_MAP4K4
Drug2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3

NCOA2 NCOA1 PPARGC1A

5.44e-0711353ctd:C061137
Drugdihydroxy-vitamin D3

NCOA2 NCOA1 PPARGC1A

9.42e-0713353ctd:C118756
Drughomopiperazine

ROCK1 PSTPIP1 ITGA4

7.48e-0625353CID000068163
Druglithocholic acid acetate

NCOA2 NCOA1 PPARGC1A

8.44e-0626353ctd:C502354
DrugBicuculline (+) [485-49-4]; Down 200; 10.8uM; PC3; HT_HG-U133A

TNIK SRCAP INCENP ATP8B2 MINK1

1.18e-051963554574_DN
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

NCOA2 TCHH INCENP ATP8B2 MINK1

1.21e-051973555201_DN
DrugBupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; PC3; HT_HG-U133A

CEP350 NCOA1 ATP8B2 MINK1 MAPK8IP3

1.30e-052003555782_DN
DrugMagnetite Nanoparticles

NCOA2 ROCK1 SPAG9 ZBTB2 TRMT6 KIF5B ITGA4 ADAM28 ADD3 RSF1

1.88e-0513103510ctd:D058185
Drugbutamben

NCOA2 NCOA1

3.43e-056352ctd:C004605
Drug2',3',4',5'-tetrachloro-4-biphenylol

NCOA2 NCOA1

3.43e-056352ctd:C104006
DrugIsoxazoles

NCOA1 PPARGC1A

6.39e-058352ctd:D007555
Drug2-acetyltributylcitrate

NCOA2 NCOA1

8.21e-059352ctd:C014953
Drugtris(chloroethyl)phosphate

NCOA2 NCOA1 PPARGC1A

8.26e-0555353ctd:C031324
DrugSuccimer

NCOA2 ROCK1 SPAG9 TRMT6 KIF5B ITGA4 ADAM28 ADD3 RSF1

9.25e-051264359ctd:D004113
DrugGGTI-298

SMARCA4 ROCK1 ITGA4

1.24e-0463353CID009811606
DrugAndrostenols

NCOA2 NCOA1

1.50e-0412352ctd:D000737
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA

CEP350 SMARCA4 KIF5B ADD3

1.53e-04177354985_DN
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A

SMARCA4 SPAG9 KIF5B ADD3

1.60e-041793544585_DN
DrugLFA703

ROCK1 ITGA4

1.77e-0413352CID000449169
DrugButylparaben [94-26-8]; Down 200; 20.6uM; PC3; HT_HG-U133A

TNIK SMARCA4 SPAG9 INCENP

2.05e-041913544647_DN
DrugQuercetine dihydrate [6151-25-3]; Down 200; 11.8uM; HL60; HT_HG-U133A

NCOA1 PSTPIP1 SRCAP ATP8B2

2.05e-041913542499_DN
DrugAstemizole [68844-77-9]; Down 200; 8.8uM; HL60; HG-U133A

UPF3B ITGA4 ADD3 MINK1

2.09e-041923541365_DN
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

NCOA1 SRCAP MINK1 MAPK8IP3

2.09e-041923541165_UP
DrugDeltaline [6836-11-9]; Up 200; 7.8uM; PC3; HT_HG-U133A

ITGA4 SRCAP ADAM28 MINK1

2.13e-041933544306_UP
DrugPramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; PC3; HT_HG-U133A

NCOA2 SRCAP INCENP MAPK8IP3

2.13e-041933543811_UP
DrugClotrimazole [23593-75-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A

ITGA4 SRCAP MINK1 MAPK8IP3

2.13e-041933543166_UP
DrugEtofylline [519-37-9]; Down 200; 17.8uM; HL60; HG-U133A

NCOA2 NCOA1 UPF3B KIF5B

2.18e-041943541409_DN
Druglomustine; Down 200; 100uM; MCF7; HT_HG-U133A

SMARCA4 SRCAP ADD3 MINK1

2.18e-041943547089_DN
DrugNaproxen [22204-53-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A

CEP350 SRCAP MINK1 MAPK8IP3

2.18e-041943545457_DN
Drug11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

NCOA2 SPAG9 INCENP MINK1

2.18e-041943547538_DN
DrugDyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A

SRCAP INCENP ATP8B2 MAPK8IP3

2.18e-041943547423_DN
DrugMethyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A

NCOA1 SRCAP ATP8B2 MINK1

2.22e-041953543850_DN
DrugDelcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A

NCOA2 SRCAP INCENP MAPK8IP3

2.22e-041953544737_DN
DrugMethacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

NCOA2 TCHH SRCAP MINK1

2.22e-041953543452_UP
DrugSpaglumic acid [4910-46-7]; Down 200; 13.2uM; HL60; HT_HG-U133A

TNIK SRCAP ATP8B2 ADAM28

2.22e-041953542962_DN
DrugKetanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; HL60; HG-U133A

SMARCA4 ITGA4 CLPB MAPK8IP3

2.26e-041963541593_DN
DrugTestosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A

NCOA1 TCHH ATP8B2 MINK1

2.26e-041963545636_DN
DrugDiphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; MCF7; HT_HG-U133A

NCOA2 SPAG9 ATP8B2 MINK1

2.26e-041963541494_DN
DrugPentoxifylline [6493-05-6]; Down 200; 14.4uM; HL60; HG-U133A

CEP350 MINK1 MAPK8IP3 RSF1

2.26e-041963541444_DN
DrugPivampicillin [33817-20-8]; Down 200; 8.6uM; HL60; HT_HG-U133A

SMARCA4 NCOA1 ITGA4 CLPB

2.31e-041973542945_DN
DrugE)-4-hydroxytamoxifen

NCOA2 SMARCA4 NCOA1 PPARGC1A

2.31e-04197354CID000063062
DrugProglumide [6620-60-6]; Down 200; 12uM; HL60; HT_HG-U133A

NCOA1 SPAG9 ATP8B2 MAPK8IP3

2.31e-041973542363_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

INCENP ATP8B2 MINK1 MAPK8IP3

2.31e-041973543566_DN
DrugLeflunomide [75706-12-6]; Down 200; 14.8uM; PC3; HT_HG-U133A

SMARCA4 SPAG9 INCENP MINK1

2.31e-041973545884_DN
Drug2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A

INCENP ATP8B2 MINK1 MAPK8IP3

2.31e-041973545211_DN
DrugPergolide mesylate [66104-23-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A

SMARCA4 ATP8B2 MINK1 MAPK8IP3

2.31e-041973547434_DN
DrugDAPH; Down 200; 10uM; MCF7; HG-U133A

CEP350 SMARCA4 ROCK1 ADD3

2.31e-04197354624_DN
DrugNorgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

NCOA2 SRCAP MINK1 MAPK8IP3

2.31e-041973544730_DN
Drug(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; PC3; HT_HG-U133A

ITGA4 SRCAP MAPK8IP3 CPLX2

2.35e-041983543810_UP
DrugAcetazolamide [59-66-5]; Up 200; 18uM; HL60; HT_HG-U133A

NCOA2 SRCAP INCENP ATP8B2

2.35e-041983541850_UP
DrugDesipramine hydrochloride [58-28-6]; Down 200; 13.2uM; HL60; HG-U133A

CEP350 PSTPIP1 ITGA4 RSF1

2.35e-041983541596_DN
DrugEtofylline [519-37-9]; Down 200; 17.8uM; MCF7; HT_HG-U133A

NCOA2 SPAG9 SRCAP RSF1

2.35e-041983542256_DN
DrugPyrilamine maleate [59-33-6]; Down 200; 10uM; HL60; HG-U133A

CEP350 NCOA1 CLPB MAPK8IP3

2.40e-041993541568_DN
DrugDiphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; HL60; HG-U133A

ITGA4 SRCAP MAPK8IP3 RSF1

2.40e-041993541994_UP
Drug(-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; PC3; HT_HG-U133A

TNIK NCOA1 SRCAP CLPB

2.40e-041993547267_DN
DrugAminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

TNIK ADAM28 MAPK8IP3 CPLX2

2.44e-042003543623_UP
DrugMinoxidil [38304-91-5]; Up 200; 19.2uM; PC3; HG-U133A

TNIK SRCAP MINK1 MAPK8IP3

2.44e-042003541914_UP
Drugdexamethasone 21-mesylate

NCOA2 NCOA1

2.72e-0416352CID000063041
Drugferutinin

NCOA2 NCOA1

2.72e-0416352CID000354654
Drugtris(2-butoxyethyl) phosphate

NCOA2 NCOA1 PPARGC1A

2.91e-0484353ctd:C013320
DrugCV-1

NCOA2 NCOA1 PPARGC1A KIF5B

3.11e-04213354CID000130105
Drug1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole

NCOA1 PPARGC1A

3.46e-0418352ctd:C524478
Drugandrost-2-en-3-ol

NCOA2 NCOA1

3.46e-0418352CID000166036
Diseasediabetic retinopathy (implicated_via_orthology)

PPARGC1A ITGA4

1.72e-0416362DOID:8947 (implicated_via_orthology)
Diseaselung non-small cell carcinoma (is_implicated_in)

NCOA2 SMARCA4 ADAM28

6.52e-04139363DOID:3908 (is_implicated_in)
DiseaseBurkitt Lymphoma

SMARCA4 HLA-C

8.88e-0436362C0006413
Diseaseprostate cancer (is_marker_for)

NCOA2 SMARCA4 NCOA1

9.11e-04156363DOID:10283 (is_marker_for)
DiseaseQRS amplitude, QRS complex

CCDC59 NSRP1

1.71e-0350362EFO_0005054, EFO_0007742
Diseaseresponse to cisplatin

TNRC18 CCDC59

1.78e-0351362GO_0072718
Diseaseneutrophil count, basophil count

NCOA1 ITGA4 HLA-C

2.56e-03224363EFO_0004833, EFO_0005090
Diseasebreast carcinoma (is_marker_for)

NCOA1 ADAM28

2.96e-0366362DOID:3459 (is_marker_for)
Diseaseparental longevity

CEP350 SMARCA4 PPARGC1A HLA-C

2.99e-03494364EFO_0007796
DiseaseManic Disorder

ADD3 CPLX2

3.41e-0371362C0024713
DiseaseManic

ADD3 CPLX2

4.10e-0378362C0338831
DiseaseDepression, Bipolar

ADD3 CPLX2

4.20e-0379362C0005587

Protein segments in the cluster

PeptideGeneStartEntry
EFKRYNENQDEIRKR

ADAM28

216

Q9UKQ2
VLEKRNKIREQNRYD

ADD3

501

Q9UEY8
EERRARANDREYNEK

ATP8B2

31

P98198
EKDREKYSQREQERD

NSRP1

381

Q9H0G5
ERYENNDKYRDREKR

NSRP1

426

Q9H0G5
RDEKQRRKEQYIRER

NEXN

51

Q0ZGT2
DRKRYQQEVDRIKEA

KIF5B

891

P33176
RREQKREQYRQVKAH

SPAG9

621

O60271
EEFRERQKEQRKKYE

PSTPIP1

106

O43586
EQKREQYRQVREHVR

MAPK8IP3

641

Q9UPT6
RKKRRISYVQDENRD

INCENP

66

Q9NQS7
QKQRREKAAREYRVN

EXD1

311

Q8NHP7
RETQKYKRQAQADRV

HLA-C

86

P10321
RLEYQRRKQEAEEKA

KIAA2012

1126

Q0VF49
RREYEKRESERAKQR

PPARGC1A

651

Q9UBK2
LKRQEEERRRQKERY

UPF3B

366

Q9BZI7
ADREKYRRLNEQRQM

DENND11

356

A4D1U4
VRQYIVRQQEERKRK

CEP350

596

Q5VT06
KRQYKSILQEENRRD

ITGA4

1006

P13612
KYQEKQRKREAEERR

CLPB

321

Q9H078
RSRRNQKRQINYKED

RSF1

1206

Q96T23
EAEREKVRQQIRDKY

CPLX2

56

Q6PUV4
ERRQAEREQEYKRKQ

MINK1

441

Q8N4C8
EREQEYKRKQLEEQR

MINK1

446

Q8N4C8
TEKRRREQENKYLEE

NCOA1

31

Q15788
NRQEQTESRERKYMR

PKDREJ

1411

Q9NTG1
KIEQERKRRQKHQEY

SMARCA4

461

P51532
ERRKQEREEAQRQYK

CCDC59

191

Q9P031
QRQKEERARREEQAK

SRCAP

176

Q6ZRS2
KRNTEKRNREQENKY

NCOA2

31

Q15596
RLAEVQRQYKEKQRE

TNRC18

1486

O15417
RKQQEREQRRHYEEQ

TNIK

416

Q9UKE5
RRQAKLEKEEAERYQ

SMC1B

196

Q8NDV3
NDYEKVVKRQREERQ

RBM17

106

Q96I25
NEYQRKAEQENEKRR

ROCK1

496

Q13464
DYIQEKQRRQEEQRK

TRMT6

341

Q9UJA5
QADQEREVKRRKYEC

ZBTB2

351

Q8N680
EEREKRRRQEQERQY

TCHH

916

Q07283
EEREKRRRQERERQY

TCHH

946

Q07283
EEQEKRRQERERQYR

TCHH

1186

Q07283
ERQYREEEELQRQKR

TCHH

1196

Q07283
EEEELQRQKRKQRYR

TCHH

1201

Q07283
QRQKRKQRYRDEDQR

TCHH

1206

Q07283