Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction3',5'-cyclic-AMP phosphodiesterase activity

PDE4A PDE4B PDE4C PDE4D

1.01e-05221264GO:0004115
GeneOntologyMolecularFunction3',5'-cyclic-GMP phosphodiesterase activity

PDE4A PDE4B PDE4C PDE4D

1.46e-05241264GO:0047555
GeneOntologyMolecularFunction3',5'-cyclic-nucleotide phosphodiesterase activity

PDE4A PDE4B PDE4C PDE4D

1.73e-05251264GO:0004114
GeneOntologyMolecularFunctioncyclic-nucleotide phosphodiesterase activity

PDE4A PDE4B PDE4C PDE4D

2.37e-05271264GO:0004112
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

PDE4A PDE4B PDE4C PDE4D PLCXD1

3.74e-04971265GO:0008081
GeneOntologyMolecularFunctioncAMP binding

PDE4A PDE4B PDE4D

5.10e-04251263GO:0030552
GeneOntologyMolecularFunctionD-loop DNA binding

WRN RAD51AP1

5.83e-0461262GO:0062037
GeneOntologyBiologicalProcesscAMP catabolic process

PDE4A PDE4B PDE4C PDE4D

1.74e-0791284GO:0006198
GeneOntologyBiologicalProcesscyclic nucleotide catabolic process

PDE4A PDE4B PDE4C PDE4D

1.35e-06141284GO:0009214
GeneOntologyBiologicalProcesscAMP metabolic process

PDE4A PDE4B PDE4C PDE4D

1.62e-05251284GO:0046058
GeneOntologyBiologicalProcessnegative regulation of relaxation of cardiac muscle

PDE4B PDE4D

3.82e-0521282GO:1901898
GeneOntologyBiologicalProcessgastrulation

MKKS SUPT20H KIF16B NSD1 EPB41L5 HIRA TGFBR2 SETD2

5.43e-052121288GO:0007369
GeneOntologyBiologicalProcessDNA recombination

RAG1 RNF168 WRN SPO11 TEP1 APLF RAD51AP1 SETD2 USP51 GEN1

1.02e-0436812810GO:0006310
DomainPDEase

PDE4A PDE4B PDE4C PDE4D

6.86e-06191254IPR023088
DomainPDEase_I

PDE4A PDE4B PDE4C PDE4D

1.05e-05211254PF00233
DomainPDEASE_I

PDE4A PDE4B PDE4C PDE4D

1.05e-05211254PS00126
DomainPDEase_CS

PDE4A PDE4B PDE4C PDE4D

1.05e-05211254IPR023174
Domain-

PDE4A PDE4B PDE4C PDE4D

1.27e-052212541.10.1300.10
DomainPDEase_catalytic_dom

PDE4A PDE4B PDE4C PDE4D

1.53e-05231254IPR002073
DomainHD/PDEase_dom

PDE4A PDE4B PDE4C PDE4D

1.83e-05241254IPR003607
DomainHDc

PDE4A PDE4B PDE4C PDE4D

1.83e-05241254SM00471
DomainCoatomer_g_Cpla

COPG1 COPG2

4.44e-0521252IPR032154
Domain-

COPG1 COPG2

4.44e-05212522.60.40.1480
DomainCOP-gamma_platf

COPG1 COPG2

4.44e-0521252PF08752
DomainCoatomer_g_Cpla

COPG1 COPG2

4.44e-0521252PF16381
DomainCoatomer_gsu_app_Ig-like-sub

COPG1 COPG2

4.44e-0521252IPR013040
DomainCoatomer_gsu

COPG1 COPG2

4.44e-0521252IPR017106
DomainARM-type_fold

DOCK2 COPG1 VEPH1 MROH5 ARFGEF2 COPG2 TSC2 MROH8 EIF4G3 UNC79

9.52e-0533912510IPR016024
DomainPost-SET_dom

NSD1 KMT2C SETD2

1.54e-04161253IPR003616
DomainPostSET

NSD1 KMT2C SETD2

1.54e-04161253SM00508
DomainPOST_SET

NSD1 KMT2C SETD2

1.54e-04161253PS50868
DomainClathrin_a/coatomer_app_sub_C

COPG1 COPG2

2.64e-0441252IPR015873
Domain-

COPG1 COPG2

2.64e-04412523.30.310.30
DomainAWS

NSD1 SETD2

4.39e-0451252SM00570
DomainAWS

NSD1 SETD2

4.39e-0451252PS51215
DomainAWS_dom

NSD1 SETD2

4.39e-0451252IPR006560
DomainCoatomer/calthrin_app_sub_C

COPG1 COPG2

1.21e-0381252IPR009028
DomainPlexin_cytopl

PLXNC1 PLXNA1

1.55e-0391252PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNC1 PLXNA1

1.55e-0391252IPR013548
DomainPlexin

PLXNC1 PLXNA1

1.55e-0391252IPR031148
DomainSET

NSD1 KMT2C SETD2

2.59e-03411253PF00856
DomainCoatomer/clathrin_app_Ig-like

COPG1 COPG2

2.81e-03121252IPR013041
DomainPSI

ITGB6 PLXNC1 PLXNA1

3.17e-03441253IPR016201
DomainFA

EPB41L5 FRMD3

3.30e-03131252PF08736
DomainFERM-adjacent

EPB41L5 FRMD3

3.30e-03131252IPR014847
DomainFA

EPB41L5 FRMD3

3.30e-03131252SM01195
DomainSET

NSD1 KMT2C SETD2

3.60e-03461253SM00317
DomainPSI

ITGB6 PLXNC1 PLXNA1

3.60e-03461253SM00423
DomainClathrin/coatomer_adapt-like_N

COPG1 COPG2

4.41e-03151252IPR002553
DomainAdaptin_N

COPG1 COPG2

4.41e-03151252PF01602
DomainSET_dom

NSD1 KMT2C SETD2

4.56e-03501253IPR001214
DomainSET

NSD1 KMT2C SETD2

4.56e-03501253PS50280
PathwayREACTOME_DARPP_32_EVENTS

PDE4A PDE4B PDE4C PDE4D

3.60e-0616974MM14699
PathwayWP_SILDENAFIL_TREATMENT

PDE4A PDE4B PDE4C PDE4D

1.69e-0523974M46455
PathwayREACTOME_DARPP_32_EVENTS

PDE4A PDE4B PDE4C PDE4D

2.01e-0524974M751
Pubmed

Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.

PDE4A PDE4B PDE4C PDE4D

1.75e-10412849371714
Pubmed

Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice.

PDE4A PDE4B PDE4C PDE4D

1.75e-104128434943270
Pubmed

PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice.

PDE4A PDE4B PDE4C PDE4D

1.75e-104128432738081
Pubmed

A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs.

PDE4A PDE4B PDE4C PDE4D

1.75e-10412848413254
Pubmed

Role of phosphodiesterases in the shaping of sub-plasma-membrane cAMP oscillations and pulsatile insulin secretion.

PDE4A PDE4B PDE4C PDE4D

1.75e-104128422946044
Pubmed

Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice.

PDE4A PDE4B PDE4C PDE4D

1.75e-104128433609559
Pubmed

Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine.

PDE4A PDE4B PDE4C PDE4D

1.75e-104128424732776
Pubmed

The cAMP-phosphodiesterase 4 (PDE4) controls β-adrenoceptor- and CFTR-dependent saliva secretion in mice.

PDE4A PDE4B PDE4C PDE4D

8.73e-105128433944911
Pubmed

A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons.

PDE4A PDE4B PDE4C PDE4D

8.73e-10512848586960
Pubmed

Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.

PDE4A PDE4B PDE4C PDE4D

2.61e-096128418923023
Pubmed

The upstream conserved regions (UCRs) mediate homo- and hetero-oligomerization of type 4 cyclic nucleotide phosphodiesterases (PDE4s).

PDE4A PDE4B PDE4D

4.87e-083128324555506
Pubmed

Differential expression and function of phosphodiesterase 4 (PDE4) subtypes in human primary CD4+ T cells: predominant role of PDE4D.

PDE4A PDE4B PDE4D

4.87e-083128317404263
Pubmed

Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.

PDE4A PDE4B PDE4D

4.87e-083128316034090
Pubmed

Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation.

PDE4A PDE4B PDE4D

4.87e-083128315585880
Pubmed

Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect.

PDE4A PDE4B PDE4D

4.87e-083128310213096
Pubmed

Critical role of PDE4D in beta2-adrenoceptor-dependent cAMP signaling in mouse embryonic fibroblasts.

PDE4A PDE4B PDE4D

4.87e-083128318508768
Pubmed

Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse.

PDE4A PDE4B PDE4C PDE4D

1.22e-071312848009369
Pubmed

Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice.

PDE4A PDE4B PDE4D

1.94e-074128321670503
Pubmed

Truncated form of TGF-βRII, but not its absence, induces memory CD8+ T cell expansion and lymphoproliferative disorder in mice.

RAG1 IL15 TGFBR2

1.94e-074128323686479
Pubmed

Phosphodiesterase 4D is required for beta2 adrenoceptor subtype-specific signaling in cardiac myocytes.

PDE4A PDE4B PDE4D

1.94e-074128315644445
Pubmed

Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.

PDE4A PDE4B PDE4D

1.94e-074128311839681
Pubmed

Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function.

PDE4A PDE4B PDE4D

4.84e-075128321652625
Pubmed

Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages.

PDE4A PDE4B PDE4D

4.84e-075128328383060
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SART3 ZSWIM8 COPG1 MTHFD1L NSD1 DIDO1 COPG2 THOC2 DHX8 DST ATP1A1 EIF4G3 AQR

9.41e-076531281322586326
Pubmed

Overview of PDEs and their regulation.

PDE4A PDE4B PDE4C PDE4D

2.09e-0625128417307970
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SART3 SUPT20H MTHFD1L WRN NSD1 EPB41L5 DIDO1 COPG2 HIRA DHX8 KMT2C SETD2 DST TIAL1 MACO1 ISG20L2 KDM1B EIF4G3 AQR

2.49e-0614971281931527615
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

DOCK2 PDE4B PDE4D TSC2 NUFIP1 RAD51AP1 PTPRZ1

3.52e-06171128720201926
Pubmed

Tagging genes with cassette-exchange sites.

ARFGEF2 DIDO1 RNF17 RAD51AP1 MALT1 KMT2C ZMYM1 PLXNA1 AQR

4.48e-06335128915741177
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

SART3 LAMB4 SUPT20H COPG1 MTHFD1L BAG5 WRN USP25 DHX8 RAD51AP1 OPTN STAMBPL1 KDM1B EIF4G3 AQR

4.66e-0610051281519615732
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

TACO1 SART3 COPG1 MTHFD1L COPG2 ADAR ARPC1B DHX8 TIAL1 ATP1A1 CTPS1 EIF4G3

1.21e-057041281229955894
Pubmed

Effects of PDE4 gene polymorphisms on efficacy and adverse drug events of ritodrine therapy in preterm labor patients: a prospective observational study.

PDE4B PDE4D

1.34e-052128231324945
Pubmed

NSD1 Inactivation and SETD2 Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas.

NSD1 SETD2

1.34e-052128228754676
Pubmed

Overexpression of phosphodiesterase-4 subtypes involved in surgery-induced neuroinflammation and cognitive dysfunction in mice.

PDE4B PDE4D

1.34e-052128228235598
Pubmed

Expression and prognostic value of NSD1 and SETD2 in pancreatic ductal adenocarcinoma and its precursor lesions.

NSD1 SETD2

1.34e-052128231060750
Pubmed

The innate NK cells, allograft rejection, and a key role for IL-15.

RAG1 IL15

1.34e-052128218523245
Pubmed

Dendritic cell-specific disruption of TGF-β receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity.

RAG1 TGFBR2

1.34e-052128222972928
Pubmed

DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8+ T Cell Compartment by Negatively Regulating Tonic TCR Triggering.

DOCK2 RAG1

1.34e-052128231740487
Pubmed

Genomic profiling identifies alterations in TGFbeta signaling through loss of TGFbeta receptor expression in human renal cell carcinogenesis and progression.

TGFBR2 TGFBR3

1.34e-052128212970754
Pubmed

PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts.

PDE4B PDE4D

1.34e-052128221288894
Pubmed

Acquired Cystic Kidney Disease-associated Renal Cell Carcinoma (ACKD-RCC) Harbor Recurrent Mutations in KMT2C and TSC2 Genes.

TSC2 KMT2C

1.34e-052128232604168
Pubmed

Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes.

PDE4A PDE4D

1.34e-05212829520403
Pubmed

Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors.

PDE4B PDE4C

1.34e-052128217727341
Pubmed

Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4.

PDE4B PDE4D

1.34e-052128229123207
Pubmed

Phosphodiesterase 4B is essential for T(H)2-cell function and development of airway hyperresponsiveness in allergic asthma.

PDE4A PDE4B

1.34e-052128221047676
Pubmed

IL-15-high-responder developing NK cells bearing Ly49 receptors in IL-15-/- mice.

RAG1 IL15

1.34e-052128221967894
Pubmed

Expression of transforming growth factor-beta receptors types II and III within various cells in the rat periodontium.

TGFBR2 TGFBR3

1.34e-052128210207840
Pubmed

Functional roles for the cytoplasmic domain of the type III transforming growth factor beta receptor in regulating transforming growth factor beta signaling.

TGFBR2 TGFBR3

1.34e-052128211323414
Pubmed

Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion.

IL15 TGFBR2

1.34e-052128232582853
Pubmed

Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4.

PDE4A PDE4C

1.34e-052128223043089
Pubmed

Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.

PDE4B PDE4D

1.34e-052128215003452
Pubmed

TGF-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation.

RAG1 TGFBR2

1.34e-052128222634866
Pubmed

PDE4D plays a critical role in the control of airway smooth muscle contraction.

PDE4B PDE4D

1.34e-052128214519662
Pubmed

IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.

RAG1 IL15

1.34e-052128218689546
Pubmed

Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B).

PDE4B PDE4D

1.34e-052128217700644
Pubmed

A-MYB (MYBL1) transcription factor is a master regulator of male meiosis.

SPO11 MYBL1

1.34e-052128221750041
Pubmed

PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases.

PDE4B PDE4D

1.34e-052128217088426
Pubmed

Diazepam and rolipram differentially inhibit cyclic AMP-specific phosphodiesterases PDE4A1 and PDE4B3 in the mouse.

PDE4A PDE4B

1.34e-052128211267656
Pubmed

Multi-dimensional Insight into the Coexistence of Pathogenic Genes for ADAR1 and TSC2: Careful Consideration is Essential for Interpretation of ADAR1 Variants.

TSC2 ADAR

1.34e-052128237740860
Pubmed

Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation.

NSD1 SETD2

1.34e-052128218157086
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NWD1 SUPT20H MTHFD1L ALDH1L1 NEB KMT2C TIAL1 ATP1A1 RMND1 CTPS1

1.64e-054971281036774506
Pubmed

Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.

PDE4A PDE4B PDE4D

1.72e-0514128325852085
Pubmed

Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.

PDE4A PDE4B PDE4D

2.63e-0516128328283561
Pubmed

A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling.

RAG1 TGFBR2

4.02e-053128225577439
Pubmed

An E2-guided E3 Screen Identifies the RNF17-UBE2U Pair as Regulator of the Radiosensitivity, Immunodeficiency, Dysmorphic Features, and Learning Difficulties (RIDDLE) Syndrome Protein RNF168.

RNF168 RNF17

4.02e-053128227903633
Pubmed

Leukocyte phosphodiesterase expression after lipopolysaccharide and during sepsis and its relationship with HLA-DR expression.

PDE4A PDE4B

4.02e-053128228356347
Pubmed

T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development.

IL15 TGFBR2

4.02e-053128232268106
Pubmed

Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma.

VEPH1 TSC2

4.02e-053128232610114
Pubmed

Targeting KDM2A Enhances T-cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma.

RAG1 NSD1

4.02e-053128237311054
Pubmed

Receptors for the TGF-beta family.

TGFBR2 TGFBR3

4.02e-05312821319842
Pubmed

Abnormal transforming growth factor-beta expression in mesenchymal stem cells from patients with osteoarthritis.

TGFBR2 TGFBR3

4.02e-053128218398939
Pubmed

Polymorphism of Transforming Growth Factor TGFB and Its Receptors TGFBRI, TGFBRII, TGFBRIIII Genes in Western Siberia Patients with Open-Angle Glaucoma.

TGFBR2 TGFBR3

4.02e-053128238730107
Pubmed

Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice.

SPO11 EIF4G3

4.02e-053128229161344
Pubmed

Genetic susceptibility to Dupuytren's disease: transforming growth factor beta receptor (TGFbetaR) gene polymorphisms and Dupuytren's disease.

TGFBR2 TGFBR3

4.02e-053128212873459
Pubmed

TGF-beta receptors: a complicated system of multiple binding proteins.

TGFBR2 TGFBR3

4.02e-05312828268187
Pubmed

Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication.

PDE4A PDE4B

4.02e-053128211114167
Pubmed

Real-time monitoring of the interactions of transforming growth factor-beta (TGF-beta ) isoforms with latency-associated protein and the ectodomains of the TGF-beta type II and III receptors reveals different kinetic models and stoichiometries of binding.

TGFBR2 TGFBR3

4.02e-053128211382746
Pubmed

Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Rα.

RAG1 IL15

4.02e-053128223904478
Pubmed

Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus.

COPG1 COPG2

4.02e-053128211893085
Pubmed

Duodenal macrophages control dietary iron absorption via local degradation of transferrin.

TSC2 TF

4.02e-053128237018657
Pubmed

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

TGFBR2 TGFBR3

4.02e-053128212070302
Pubmed

In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2.

TGFBR2 TGFBR3

4.02e-053128214996829
Pubmed

Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment.

RAG1 ZNF335

4.02e-053128225343476
Pubmed

Signal transduction and TGF-beta superfamily receptors.

TGFBR2 TGFBR3

4.02e-05312828883836
Pubmed

Transforming growth factor beta in tissue fibrosis.

TGFBR2 TGFBR3

4.02e-05312827935686
Pubmed

An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes.

SPO11 MYBL1

4.02e-053128223523368
Pubmed

Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells.

RAG1 IL15

4.02e-053128219604492
Pubmed

Transient enhanced IL-2R signaling early during priming rapidly amplifies development of functional CD8+ T effector-memory cells.

RAG1 IL15

4.02e-053128223018461
Pubmed

IL-15 sustains IL-7R-independent ILC2 and ILC3 development.

RAG1 IL15

4.02e-053128228361874
Pubmed

Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and Degradation.

RAG1 OPTN

4.02e-053128233627378
Pubmed

The Salivary Gland Acts as a Sink for Tissue-Resident Memory CD8(+) T Cells, Facilitating Protection from Local Cytomegalovirus Infection.

IL15 TGFBR2

4.02e-053128226526997
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

COPG1 ARFGEF2 EPB41L5 COPG2 TSC2

4.29e-05104128531240132
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PDE4B AMER1 ARHGAP15 NSD1 DGKA DIDO1 COPG2 THOC2 KMT2C FMN1 ZMYM1 KDM1B CPLANE1 GEN1

4.83e-0510841281411544199
Pubmed

Foxf2 is required for secondary palate development and Tgfβ signaling in palatal shelf mesenchyme.

ITGB6 TGFBR2 TGFBR3

6.17e-0521128327180663
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

COPG2 ADAR APLF ARPC1B TIAL1 ISG20L2 CTPS1 EIF4G3

7.18e-05370128822922362
Pubmed

Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart.

TGFBR2 TGFBR3

8.02e-054128210092230
Pubmed

Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation.

RAG1 MALT1

8.02e-054128225456129
Pubmed

Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis.

RAG1 IL15

8.02e-054128232102931
Pubmed

Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms.

IL15 TGFBR2

8.02e-054128216973386
Pubmed

Assignment of the human helix-loop-helix transcription factor gene musculin/activated B-cell factor-1 (MSC) to chromosome 8q21 and its mouse homologue (Msc) to the proximal region of chromosome 1.

DST MYBL1

8.02e-054128210198176
Pubmed

Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling.

TGFBR2 TGFBR3

8.02e-054128228633389
GeneFamilyPhosphodiesterases

PDE4A PDE4B PDE4C PDE4D

5.41e-0624894681
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD1 KMT2C SETD2

6.18e-0434893487
GeneFamilyPlexins

PLXNC1 PLXNA1

8.43e-049892683
GeneFamilyMaestro heat like repeat containing

MROH5 MROH8

1.28e-0311892636
GeneFamilyExonucleases

WRN ISG20L2

2.75e-0316892544
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEPH1 KIF16B PTGIS SNX30 MALT1 FMN1 KIAA1755

6.77e-071721287f814b6134ad608015765399d54cc1e5e1873ed34
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

6.77e-071721287ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCellAdult-Immune-natural_killer_cell-D175|Adult / Lineage, Cell type, age group and donor

NCALD ARHGAP15 ZXDA ZFYVE28 TGFBR3 STAMBPL1 MYBL1

9.18e-071801287fc59e28f39e7d4fb1bcc7205202cf39224b70d7b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE4D PLCXD1 VEPH1 ITGB6 SNX30 FMN1 ATP1A1

1.18e-0618712875df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.23e-0618812870d7296ad26e97ad91c6927a6cfe4e6e70a74c5a6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.32e-0619012877c402aa47f1bd7decacc366c1ed1a37e39b95c73
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE4D RGS7BP PLCXD1 VEPH1 ITGB6 SNX30 FMN1

1.41e-061921287fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.51e-06194128796f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NCALD ARHGAP15 DGKA ZFYVE28 MALT1 STAMBPL1 MYBL1

1.51e-0619412873d6f2d190dd50804afea299957cc44c2bb756134
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

DOCK2 ARHGAP15 EMILIN2 NCF2 MALT1 PLXNC1 FMN1

1.51e-061941287800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellAdult-Immune-T_lymphocyte-D231|Adult / Lineage, Cell type, age group and donor

DOCK2 NCALD ARHGAP15 DGKA ZFYVE28 TRBV23-1 MYBL1

1.51e-0619412875c1dca33f382f37a7deb23e573578343c3b54986
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.57e-06195128791a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4A ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.57e-06195128762dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.62e-0619612877026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.68e-0619712876ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.68e-061971287e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 NCALD RGS7BP MTHFD1L PTGIS CREB5 STAMBPL1

1.68e-061971287bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 CREB5 PLXNC1

1.68e-061971287a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.68e-061971287c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.68e-0619712873896729740d151f0eb845f1961c7b969bfbdd28d
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK2 PDE4B ARHGAP15 NCF2 ADAR CREB5 PLXNC1

1.68e-0619712871acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4A ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.68e-0619712871eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.68e-06197128772cd61b868d57862ec9c230ea68913d3829b0f2b
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.73e-061981287ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellCOVID-19-kidney-Macrophages|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.73e-061981287161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL15 EMILIN2 DGKA NCF2 NEB STAMBPL1

9.54e-061691286813472d429c0b12580b17b440e00a6d8beb7947f
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEPH1 KIF16B SNX30 MALT1 FMN1 KIAA1755

1.05e-0517212861f335ccb92b22d0412954e8fc3af212f96410b67
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.05e-05172128672fbfa890995e47048b47199c170cc7dcd7661f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.05e-0517212862ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEPH1 KIF16B SNX30 MALT1 FMN1 KIAA1755

1.05e-051721286bb96c896d125e10b71e94e2bdad243899045af5c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 ZXDA SLC35F3 STAMBPL1

1.20e-0517612868488997e0f02e874f53fae1690da63e0dd1d0780
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PDE4B ARHGAP15 ARPC1B TGFBR2 PTPRZ1 KIAA1755

1.24e-05177128659726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP15 DGKA MALT1 OPTN TBC1D4 FMN1

1.45e-0518212869ba85f621a846531a2a7861e9df695d288c9e149
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

ADAR ITGB6 KMT2C SETD2 OPTN DST

1.50e-0518312868f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB4 KIF16B ITGB6 TBC1D4 FMN1 STAMBPL1

1.55e-051841286d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCXD1 EPB41L5 ETNPPL ALDH1L1 CFAP65 PTPRZ1

1.55e-0518412866b0c110d8930df99043c3b99cf4d873985126960
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCXD1 EPB41L5 ETNPPL ALDH1L1 CFAP65 PTPRZ1

1.55e-05184128635928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBXO40 RGS7BP RAD51AP1 PTPRZ1 PLXNA1 MYBL1

1.55e-051841286d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD1 RGS7BP CCDC81 PTGIS PTPRZ1 FRMD3

1.69e-051871286ddfc2d1d9fcc3d8e4d3d015576bb17eebf44ada9
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE4B TF CREB5 SLC5A11 KIAA1755 MAML2

1.75e-051881286b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCellCOPD-Myeloid-cMonocyte|COPD / Disease state, Lineage and Cell class

PDE4A PDE4B EMILIN2 CREB5 PLXNC1 FMN1

1.80e-051891286d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCellCOPD-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

PDE4A PDE4B PDE4D MALT1 PLXNC1 FMN1

1.80e-0518912866294691231c7d38707323cf31578a107d3b2c622
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB4 KIF16B ITGB6 TBC1D4 FMN1 ATP1A1

1.80e-051891286e059be2965cca70ff5576df055d0af1775b76e00
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP15 DGKA OPTN TBC1D4 FMN1 MAML2

1.80e-0518912868130102c41b2978a8b83f765ce383f836a464795
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ETNPPL ALDH1L1 CREB5 SLC5A11 KIAA1755 MAML2

1.80e-051891286784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 FMN1

1.80e-0518912867ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCellASK440-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

PDE4B PDE4D ARHGAP15 DGKA STAMBPL1 MYBL1

1.80e-051891286868a387d19eb02bf41933e786b7d23e920a5d433
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

PRUNE2 NCALD PDE4D RGS7BP MTHFD1L STAMBPL1

1.80e-0518912866b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK2 PDE4A ARHGAP15 EMILIN2 NCF2 MALT1

1.85e-051901286ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ETNPPL ALDH1L1 SLC5A11 PTPRZ1 KIAA1755 MAML2

1.85e-0519012862de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

DOCK2 IL15 PDE4B ARHGAP15 EMILIN2 FMN1

1.91e-0519112863b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B KIF16B EMILIN2 NCF2 FMN1

1.91e-051911286dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

1.91e-05191128647a2afc4102199b4bc76bd01b2967c8016186462
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDE4D ARHGAP15 KMT2C FMN1 MAML2 EIF4G3

2.03e-051931286779276e775cb2492e8dd36436295a536084a6415
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP15 DGKA OPTN TBC1D4 FMN1 MAML2

2.03e-051931286194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 FMN1

2.03e-051931286bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 FMN1

2.03e-051931286374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCellCOVID-19-Heart-Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 FMN1

2.09e-051941286f09675cd472200363c458952f00d2e41990800ee
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 PDE4D EPB41L5 ITGB6 CREB5 FRMD3

2.09e-0519412867002937e8903e037332a215d00fbc7c7843b33f2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D SUPT20H ARHGAP15 DGKA TBC1D4 FMN1

2.09e-051941286a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 FMN1

2.15e-051951286148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1

2.15e-05195128610ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP15 ARPC1B CREB5 DST PTPRZ1 KIAA1755

2.15e-0519512869fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

DOCK2 IL15 PDE4B ARHGAP15 EMILIN2 FMN1

2.15e-051951286ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP15 ARPC1B CREB5 DST PTPRZ1 KIAA1755

2.21e-0519612869afd0a7135028a446f06bb68f334e79b8f171b45
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D TGFBR3 OPTN TBC1D4 FMN1 MYBL1

2.21e-051961286e4c76e7ad68455e51fe93ce588bcec9383f8654b
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

DOCK2 PDE4B EMILIN2 NCF2 PLXNC1 FMN1

2.21e-0519612864929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK2 ARHGAP15 EMILIN2 CREB5 PLXNC1 FMN1

2.21e-051961286cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1

2.21e-051961286291c59b609985167c98a40d4e2caeea2fad74941
ToppCellCOPD-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

EMILIN2 PTGIS CREB5 TGFBR2 TGFBR3 ATP1A1

2.21e-0519612864930eeb303d174c28fd91021723e26fdf1af9170
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

2.27e-0519712868af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellCOVID-19-kidney-Macrophages|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 PDE4B ARHGAP15 EMILIN2 PLXNC1 FMN1

2.27e-0519712863912301018d0863144dcfac8d1fa8adc081748d7
ToppCellFetal_29-31_weeks-Immune-monocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK2 ARHGAP15 EMILIN2 NCF2 PLXNC1 FMN1

2.27e-0519712868b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 PLXNC1 FMN1

2.27e-051971286dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1

2.27e-05197128657dafb3047745a44b2345b8036e159c3641d496e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1

2.27e-051971286826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1

2.34e-05198128696883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCellCOVID-19_Severe-NK|COVID-19_Severe / disease group, cell group and cell class

NCALD PDE4D ZFYVE28 TGFBR3 OPTN MYBL1

2.34e-0519812860cb88084eac25604ec8f9b1497fb8d2433f1971c
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 PDE4B EMILIN2 NCF2 CREB5 FMN1

2.34e-051981286c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 PDE4B EMILIN2 NCF2 PLXNC1 FMN1

2.34e-0519812860b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1

2.34e-051981286623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCellImmune-monocyte|World / Lineage, Cell type, age group and donor

DOCK2 ARHGAP15 EMILIN2 NCF2 CREB5 PLXNC1

2.34e-051981286d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PDE4B ARHGAP15 EMILIN2 NCF2 PLXNC1

2.41e-05199128604adf46975aa4194ea40c7480f8a517def5d929c
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VEPH1 EPB41L5 ITGB6 SNX30 FMN1 ATP1A1

2.41e-0519912868587bd98de7767a575088afbea07a1feb4516b9b
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ARHGAP15 MTHFD1L EMILIN2 NCF2 PLXNC1

2.41e-051991286744b63fba33b176ab7dde11646ccb313665505f7
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

PDE4D USP25 KMT2C MAML2 EIF4G3 MBD5

2.41e-05199128694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellCOVID-19_Moderate-CD4+_CTL|COVID-19_Moderate / disease group, cell group and cell class

NCALD PDE4D ZFYVE28 TGFBR3 OPTN MYBL1

2.47e-052001286a9c73559e2c9fda1b065bfb5ce84978995505924
ToppCellChildren_(3_yrs)-Immune-monocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK2 ARHGAP15 EMILIN2 CREB5 PLXNC1 FMN1

2.47e-052001286881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MALT1 TBC1D4 SLC35F3 MAML2

4.77e-0513712850aa4e14b32da0cda677cc0ed6ae470f6ecd77bea
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 ARHGAP15 MALT1 NDC80 MYBL1

7.10e-051491285f4bee5fdaaa4a1917e403de90e5a62353006df24
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

PCDHA5 CREB5 PTPRZ1 FMN1 CTPS1

7.10e-051491285dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

MTHFD1L MROH5 ZFYVE28 EIF4G3 FRMD3

7.10e-0514912856e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellfacs-Skin-nan-24m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NWD1 CALHM5 RNF17 CRYBA1

8.56e-051551285fa2776d258e0420b2895de1008e292ad7725dac0
ToppCellE15.5-Hematopoietic-Immune-immune_cell_unspecified|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DOCK2 ARHGAP15 EMILIN2 NCF2 ARPC1B

9.09e-0515712854263627911657e788a1d0230690ee434e8a4f9a1
ToppCellE15.5-Hematopoietic-Immune|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DOCK2 ARHGAP15 EMILIN2 NCF2 ARPC1B

9.09e-051571285de689a133863ed74d848eba0a4f392357ac28245
ToppCellE17.5-Hematopoietic|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DOCK2 ARHGAP15 EMILIN2 NCF2 ARPC1B

9.65e-051591285a5648f731f1a22d1af1be2b0e1b80e29d05bae04
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 CREB5 PRELID3A DST PLXNA1

9.94e-0516012850544bc465af208da448858d6e174ff56f2e08a46
ToppCellE17.5-Hematopoietic-Immune-immune_cell_unspecified|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DOCK2 ARHGAP15 EMILIN2 NCF2 ARPC1B

1.02e-04161128530741ca6548db2dfb5cf1faecf0d7412c91d0077
ToppCellE17.5-Hematopoietic-Immune|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DOCK2 ARHGAP15 EMILIN2 NCF2 ARPC1B

1.02e-041611285e3ff08d0b9c686253556c56ee88648206751ef2b
ToppCellPND03-Immune-Immune_Myeloid-DC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP15 TEP1 ARPC1B TBC1D4 ATOX1

1.02e-041611285f50e91f8363f20bb7c565aaca4d4961d3fe4b5b5
DrugPiclamilast

PDE4A PDE4B PDE4C PDE4D

9.23e-1041274DB01791
DrugIbudilast

PDE4A PDE4B PDE4C PDE4D

4.60e-0951274DB05266
Drug1,7-naphthyridine

PDE4A PDE4B PDE4C PDE4D

4.60e-0951274CID000009209
DrugKetotifen

PDE4A PDE4B PDE4C PDE4D

3.19e-0871274DB00920
DrugIloprost

PDE4A PDE4B PDE4C PDE4D

3.19e-0871274DB01088
DrugDyphylline

PDE4A PDE4B PDE4C PDE4D

6.35e-0881274DB00651
Drugtrequinsin

PDE4A PDE4B PDE4C PDE4D

1.14e-0791274ctd:C035964
DrugL-826,141

PDE4A PDE4B PDE4C PDE4D

1.14e-0791274ctd:C459562
Drug4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid

PDE4A PDE4B PDE4D

1.69e-0731273DB08299
DrugNVP ABE171

PDE4A PDE4B PDE4C PDE4D

1.89e-07101274ctd:C451724
DrugNSC18930

PDE4A PDE4B PDE4C PDE4D NSD1 ADAR CTPS1

2.47e-07771277CID000001189
DrugRoflumilast

PDE4A PDE4B PDE4C PDE4D

1.60e-06161274ctd:C424423
DrugD-22888

PDE4A PDE4B PDE4D

1.68e-0651273CID000197714
DrugCilomilast

PDE4A PDE4B PDE4C PDE4D

2.66e-06181274ctd:C433247
DrugAA-2379

PDE4A PDE4B PDE4C PDE4D

5.13e-06211274CID000128390
DrugHWA 153

PDE4A PDE4B PDE4C PDE4D

6.25e-06221274CID000162797
Druggriseolic acid

PDE4A PDE4B PDE4C PDE4D

7.53e-06231274CID000127607
Drugatherosperminine

PDE4A PDE4B PDE4C PDE4D

7.53e-06231274CID000096918
DrugKF18280

PDE4A PDE4B PDE4D

9.30e-0681273CID003071941
Drugdesethyl KBT-3022

PDE4A PDE4B PDE4C PDE4D

1.25e-05261274CID000127736
DrugT-440

PDE4A PDE4B PDE4C PDE4D

1.25e-05261274CID000177965
DrugRo 15-2041

PDE4A PDE4B PDE4C PDE4D

1.25e-05261274CID000132434
Drugimidazole-4-carboxamide

PDE4A PDE4B PDE4C PDE4D

2.94e-05321274CID000152917
DrugV11294 Analogue 5f

PDE4B PDE4D

3.09e-0521272CID011214587
DrugV11294 Analogue 5t

PDE4B PDE4D

3.09e-0521272CID011226695
DrugV11294 Analogue 5e

PDE4B PDE4D

3.09e-0521272CID011443441
DrugV11294 Analogue 5n

PDE4B PDE4D

3.09e-0521272CID011238279
DrugV11294 Analogue 5p

PDE4B PDE4D

3.09e-0521272CID011478659
DrugV11294 Analogue 5o

PDE4B PDE4D

3.09e-0521272CID011249748
DrugAluminium

TF ATP1A1

3.09e-0521272DB01370
DrugV11294 Analogue 5c

PDE4B PDE4D

3.09e-0521272CID011179896
DrugV11294 Analogue 5b

PDE4B PDE4D

3.09e-0521272CID011443760
DrugCis-4-Cyano-4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]Cyclohexanecarboxylic Acid

PDE4B PDE4D

3.09e-0521272DB03849
DrugT-2585.HCl

PDE4B PDE4D

3.09e-0521272CID006918355
DrugV11294 Analogue 5m

PDE4B PDE4D

3.09e-0521272CID011477773
DrugV11294 Analogue 8a

PDE4B PDE4D

3.09e-0521272CID011442865
DrugV11294 Analogue 5q

PDE4B PDE4D

3.09e-0521272CID011318772
DrugV11294 Analogue 5h

PDE4B PDE4D

3.09e-0521272CID011306698
Drug3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester

PDE4B PDE4D

3.09e-0521272DB01959
Drug4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]-2-Pyrrolidinone

PDE4B PDE4D

3.09e-0521272DB01954
DrugM 98

PDE4B PDE4D

3.09e-0521272CID006420180
DrugV11294 Analogue 5i

PDE4B PDE4D

3.09e-0521272CID011376249
DrugV11294 Analogue 5d

PDE4B PDE4D

3.09e-0521272CID011283750
Drug3-cyclopentyloxy-4-methoxybenzoic acid

PDE4B PDE4D

3.09e-0521272CID002779323
DrugV11294 Analogue 5v

PDE4B PDE4D

3.09e-0521272CID011375325
Drug3-cyclopentyloxy-4-methoxybenzaldehyde

PDE4B PDE4D

3.09e-0521272CID002735893
DrugNp-V

PDE4B PDE4D

3.09e-0521272CID009999276
Drug(S)-Rolipram

PDE4B PDE4D

3.09e-0521272DB03606
Drug1-((5-(1-aminoethyl)-2-(8-methoxy-2-(triflurormethyl)-5-quinolinyl)-4-oxazolyl) carbonyl)-4-((cyclopropylcarbonyl)amino)proline ethyl ester

PDE4B PDE4D

3.09e-0521272ctd:C554440
DrugV11294 Analogue 5r

PDE4B PDE4D

3.09e-0521272CID011168555
DrugV11294 Analogue 5j

PDE4B PDE4D

3.09e-0521272CID011433797
DrugV11294 Analogue 5a

PDE4B PDE4D

3.09e-0521272CID011386897
DrugV11294 Analogue 5k

PDE4B PDE4D

3.09e-0521272CID011456440
Drug(R)-Rolipram

PDE4B PDE4D

3.09e-0521272DB04149
Drug(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one

PDE4A PDE4D

3.09e-0521272DB06842
Drugdyphylline

PDE4A PDE4B PDE4C PDE4D

3.33e-05331274CID000003182
DrugAH 21-132

PDE4A PDE4B PDE4C PDE4D

5.29e-05371274CID003035793
DrugCI 1044

PDE4C PDE4D TF PTGIS TGFBR2

6.71e-05761275ctd:C418118
DrugCDP840

PDE4A PDE4B PDE4D

9.00e-05161273CID000127928
DrugDTIC

PDE4A PDE4B PDE4C PDE4D PLXNA1

9.11e-05811275CID005281007
DrugBW A78U

PDE4B PDE4D

9.23e-0531272CID000127779
DrugEnprofylline

PDE4A PDE4B

9.23e-0531272DB00824
DrugOrg 4428

PDE4B PDE4D

9.23e-0531272CID000166560
Drug1-Pyrrolidinebutanenitrile

PDE4B PDE4D

9.23e-0531272CID000118838
DrugCHDM

TSC2 DST

9.23e-0531272CID000007735
Drugtestosterone enanthate

PRUNE2 SART3 FBXO40 PDE4A PDE4B PDE4D BAG5 ZNF510 METTL4 ARPC1B ZMYM1 EIF4G3

9.24e-0557512712ctd:C004648
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A

EPB41L5 DGKA TSC2 NEB HIRA SETD2 EIF4G3

1.07e-0419312773412_DN
DrugTrifluridine [70-00-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A

ZSWIM8 PDE4A ARFGEF2 TEP1 PTGIS MALT1 PLXNC1

1.07e-0419312777176_UP
Drugflosulide

PDE4B PDE4D PTGIS

2.09e-04211273CID000071246
Drughypoxanthine

PDE4A PDE4B PDE4C PDE4D SUPT20H ADAR CTPS1

2.40e-042201277CID000000790
Drugsiguazodan

PDE4B PDE4C PDE4D

2.42e-04221273CID000072124
DiseaseSotos' syndrome

NSD1 SETD2

1.05e-0441242C0175695
DiseaseAutistic Disorder

FBXO40 IL15 PDE4A PDE4B NSD1 TSC2 TF

1.22e-042611247C0004352
Diseaseage-related hearing impairment

DOCK2 NCALD MTHFD1L NSD1 CREB5 SNX30 FMN1

4.54e-043241247EFO_0005782
Diseaseinfluenza A severity measurement

ZFYVE28 MAML2

6.19e-0491242EFO_0007743
DiseaseLeukemia, Myelocytic, Acute

PDE4B NSD1 TSC2 KMT2C SETD2

8.39e-041731245C0023467
DiseaseAdenoid Cystic Carcinoma

NSD1 KMT2C SETD2 MYBL1

8.53e-041001244C0010606
Diseasepneumococcal bacteremia

DOCK2 LAMB4

9.40e-04111242EFO_1001925
DiseaseDiverticular Bleeding

ARHGAP15 SLC35F3

1.33e-03131242C4505353
Diseasevascular brain injury measurement, vascular brain injury

ARHGAP15 CREB5

1.33e-03131242EFO_0006791, EFO_0006800
DiseaseDiverticular Diseases

ARHGAP15 SLC35F3

1.33e-03131242C4317009
DiseaseReplication Error Phenotype

TGFBR2 SETD2

1.77e-03151242C1721098
DiseaseMicrosatellite Instability

TGFBR2 SETD2

1.77e-03151242C0920269
DiseaseAcute Myeloid Leukemia, M1

PDE4B NSD1 TSC2 KMT2C

1.95e-031251244C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

PDE4B NSD1 TSC2 KMT2C

1.95e-031251244C1879321
DiseasePulmonary Emphysema

ITGB6 TGFBR2

2.29e-03171242C0034067
Diseasebrain infarction

SNX30 SLC35F3

2.56e-03181242EFO_0004277
Diseaseserum hepcidin measurement

TF KIAA1755

2.56e-03181242EFO_0004504
Diseasecumulative dose response to bevacizumab

TGFBR2 MAML2

2.86e-03191242EFO_0005944
Diseaseacute lymphoblastic leukemia, response to antineoplastic agent

IL15 MAML2

2.86e-03191242EFO_0000220, GO_0097327
Diseasesevere acute respiratory syndrome, COVID-19

MTHFD1L WRN CREB5 ZFYVE28 TGFBR2 TGFBR3 MAML2

2.88e-034471247EFO_0000694, MONDO_0100096
Diseasestomach cancer (is_marker_for)

ADAR ARPC1B SETD2 NDC80

3.09e-031421244DOID:10534 (is_marker_for)
Diseaseexercise test

WRN LRIT3

3.17e-03201242EFO_0004328

Protein segments in the cluster

PeptideGeneStartEntry
ASHSMCSARVQLPKK

CCDC116

16

Q8IYX3
TKRTPHKEDEAMSCS

APLF

311

Q8IW19
CMKKQPSLPLSEDAH

BAG5

166

Q9UL15
SHPSAKMVLCIATDD

AZIN2

146

Q96A70
SHDSTVCLADADKKM

ARPC1B

221

O15143
CAFSDVLPVLSMKHT

AAR2

156

Q9Y312
TAKALMEAVSHAKAP

ARFGEF2

866

Q9Y6D5
SCSDMDLLNPHRKSE

CEP44

311

Q9C0F1
KDPEKPMEACASAHV

AMER1

256

Q5JTC6
PNKKVCIESEHSMDT

ATOX1

36

O00244
EAKIIAMTCTHAALK

AQR

1031

O60306
PSKTDHCMKSELTTL

ARL13A

46

Q5H913
CMAKTHLSLSHQPDK

MTHFD1L

906

Q6UB35
NTPCKTKMLKEAHIE

ETNPPL

451

Q8TBG4
CSTSADTMKDNEKLH

KIF16B

1141

Q96L93
GKQHMSSIKEETPTC

NWD1

1036

Q149M9
DVSVSCPSLRAEMHK

RGS7BP

76

Q6MZT1
SKIETMNKSPHISNC

RAD51AP1

131

Q96B01
KPLCLMLADESDHET

RAG1

656

P15918
ICSDPLINTHSKMKV

NSD1

341

Q96L73
ESAPLMGKDKICSSH

FMN1

186

Q68DA7
MGKDKICSSHSLPLS

FMN1

191

Q68DA7
SAKAKDPDAELACSM

ZFYVE28

321

Q9HCC9
LTHKDCPITAMQKES

CREB5

436

Q02930
KPACMLTRKETEHVS

MKKS

161

Q9NPJ1
TGCARSEPKMSAHVK

KMT2C

4706

Q8NEZ4
KSEPRHSKIDKAMEC

NCF2

151

P19878
AKAHELPESMCLKFD

MALT1

581

Q9UDY8
ESDVHPSCKVTAMKC

IL15

76

P40933
MLLEKALTHSSCPEA

KIAA1755

1046

Q5JYT7
DDLVKSGHKIMTACS

DST

5886

Q03001
DLMGTCHSDSTKPAI

CFAP65

556

Q6ZU64
KACVVHGSDLKDMTS

ATP1A1

661

P05023
CTSKSPSTHKDLMEN

MACO1

356

Q8N5G2
MDSCSTSEHKLGKDS

PLXNA1

1781

Q9UIW2
SFSPRHSKCMVKNVD

PLXNC1

526

O60486
MLSTDSCKEAPDHPS

ITGB6

496

P18564
EISPMCDKHTASVEK

PDE4A

626

P27815
SPMCDKHTASVEKSQ

PDE4B

601

Q07343
DISPMCDKHTASVEK

PDE4C

581

Q08493
ISPMCDKHNASVEKS

PDE4D

656

Q08499
EDTPHAKIASDIMSC

VEPH1

101

Q14D04
KCSEITFHTTKTLPM

DGKA

681

P23743
RKADCPENATMSLKH

ISG20L2

291

Q9H9L3
AELEHCLKPSVMTSA

LRIT3

246

Q3SXY7
SFKVTLMAEEHKCLS

PTPRZ1

2146

P23471
AMDKSTFPLSGHCKV

PCDHA5

321

Q9Y5H7
EAACAHPTKTGSELM

CYHR1

186

Q6ZMK1
MTTFDTLKTLKHPCI

MROH8

346

Q9H579
DTMTYCLNKKSPISH

PLCXD1

46

Q9NUJ7
KKEPGETLSCSKHMD

MAML2

266

Q8IZL2
SLGCTMEFSKIKAHL

SLC10A1

41

Q14973
KAMLAFHTSTPAACK

FRMD3

281

A2A2Y4
QMKACATKPEELSVH

EPB41L5

381

Q9HCM4
MKPNTAIKPETSDHC

KDM1B

171

Q8NB78
ILMECAAEHPTIAKS

DOCK2

1156

Q92608
SGKSPVTTLLECMHK

ADAR

611

P55265
EKMTHEASTVKSLLC

CPLANE1

796

Q9H799
SYPSCLKHDSEMKPQ

CCDC81

296

Q6ZN84
LKHDSEMKPQTSPAC

CCDC81

301

Q6ZN84
NSDTLKLLKMSSCPH

FBXL3

196

Q9UKT7
EELHKVSCGKTSMLP

CALHM5

151

Q8N5C1
MSFRPICSANHKESK

CRYBA1

111

P05813
DCILKHAAATMKFLS

DIDO1

416

Q9BTC0
LNKVAMKHPSAVTAC

COPG2

311

Q9UBF2
AMLSCKPSEHKAVDT

FBXO40

366

Q9UH90
KSHEGITNSVMPECK

MBD5

151

Q9P267
DPHVDCYTMSSIKSK

GEN1

176

Q17RS7
ISMSAKLHDGAVACK

LAMB4

756

A4D0S4
LNKVAMKHPSAVTAC

COPG1

311

Q9Y678
VSHMEKTCSKLDSIS

EMILIN2

706

Q9BXX0
RFSTHQMKDPDPCKS

CCDC168

2006

Q8NDH2
SPAALTAEKEAMCLS

HIRA

661

P54198
ASLKRDMPKVLHDSS

SART3

686

Q15020
SAKPEISAMSAHDKA

EIF4G3

1201

O43432
RDCPSGHLSMEEFKK

NCALD

36

P61601
CSLSELCEMAKHLPS

METTL4

196

Q8N3J2
ERSSSKLQHKPCAAM

MYBL1

201

P10243
MDRHKLDVVSCGKST

DHX8

1086

Q14562
TARDMKTCRFHPDKD

P2RX3

196

P56373
SPDEMLTVHVLDCKS

OTOG

2141

Q6ZRI0
MSHQPLSCLTEKEDS

OPTN

1

Q96CV9
MTIQHCPLDKSSKAL

OR4F4

216

Q96R69
PVSTSMKDSSCMKVH

MROH5

31

Q6ZUA9
MASSDVKPKSVSHAK

MEIG1

1

Q5JSS6
SEAKQETEKHLSACM

PRUNE2

2111

Q8WUY3
DLTLLNHSMKPTDCT

FER1L5

101

A0AVI2
SLSVGDKDHMCSVKS

PTGIS

221

Q16647
VCRSKHMPKSTIETA

TACO1

111

Q9BSH4
HSVVDPVEKKMELCS

PRELID3A

81

Q96N28
SNMKTGHKPESVDLC

ARHGAP15

126

Q53QZ3
PLDTSVKEKISMFCH

CTPS1

221

P17812
SKVREHPCVESMKDN

TGFBR2

476

P37173
HSCDMTPKQSKVVKA

SLC5A11

606

Q8WWX8
ARCQDEKAHLPTMKS

RMND1

86

Q9NWS8
TVEPTHSKCLKMERN

WRN

486

Q14191
DLPFLALSCSDTHMK

OR8U3

181

Q8NH85
MKKHSARVAPLSACN

SLC35F3

1

Q8IY50
STEVGKHIMKSCAIS

ALDH1L1

651

O75891
CTSEHTEEMLKEKPR

RNF17

1356

Q9BXT8
FLSDKHKCIMTSPSL

USP51

391

Q70EK9
TMGVSKHKSESPCES

THOC2

1506

Q8NI27
TKCQSFRDHMKSVIP

TF

36

P02787
CLATLSDLKTMEKPH

TEP1

81

Q99973
AAALAACKILKEMSH

TRPM5

546

Q9NZQ8
KHMSEHTKCPELDCS

NUFIP1

191

Q9UHK0
MVSHCTTRKIKSDSP

SPO11

91

Q9Y5K1
DDPKKHVCTMETYIT

SNX30

96

Q5VWJ9
KKLAAMPDHTDVSLS

STAMBPL1

11

Q96FJ0
EAKCPVKMSHSSSGS

SUPT20H

416

Q8NEM7
KLLDCSMEIKSFHEP

USP25

1011

Q9UHP3
ACVADKHRPLEMSAK

RRP36

86

Q96EU6
ETEMHKKRFSSQCPK

TRBV23-1

76

A0A0A0MS06
MPNSTRDHCKVSKSA

RNF168

536

Q8IYW5
KAPSSLIDDCMEKFS

TBC1D4

216

O60343
AKTQIKLCEACPMHS

TBC1D4

446

O60343
DLDDTCMLHKKSESP

SETD2

731

Q9BYW2
CMLHKKSESPFRETE

SETD2

736

Q9BYW2
DSISHPLYKCSSKMV

NDP

46

Q00604
MKTTVSEAEHPLLCE

ZSWIM8

966

A7E2V4
PISSCNKLFTSKHSM

ZXDA

546

P98168
TLHVAAVASTKMSCK

ZNF510

161

Q9Y2H8
MKISDELCHPKCTSK

ZMYM1

431

Q5SVZ6
SKHQKEICSMISTPE

VWA3B

716

Q502W6
LALMPLIATSSHDCK

WDR31

291

Q8NA23
MKTHSTEKPHMCDKC

ZNF335

581

Q9H4Z2
KSCKMITEHTSNDPY

TIAL1

36

Q01085
TLLDPTCKAKMNGTH

TGFBR3

481

Q03167
DVFCKHPCLKTNMST

ZNF560

221

Q96MR9
IATLMPTKDVDKHRC

TSC2

1621

P49815
LKSHMKTCSQPLHED

UNC79

2341

Q9P2D8
CIKIHTAMKESSPLF

NDC80

191

O14777
HTPLDMVSVTAAKKS

NEB

1626

P20929