Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	1.03e-10	37	133	8	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	1.29e-10	38	133	8	GO:0070001
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	5.99e-07	11	133	4	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.79e-06	14	133	4	GO:0003964
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 POLG ERVK-7 ERVK-10 ERVK-8	5.11e-06	38	133	5	GO:0034061
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.03e-05	21	133	4	GO:0035613
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 DNASE1	1.34e-05	46	133	5	GO:0016893
GeneOntologyMolecularFunction	ABC-type glutathione S-conjugate transporter activity	ABCC1 ABCC6 ABCC2	1.58e-05	8	133	3	GO:0015431
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	ABCC1 ABCC6 ABCC2	3.35e-05	10	133	3	GO:0043225
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.05e-04	37	133	4	GO:0016891
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC1 ABCC6 ABCC2	1.24e-04	15	133	3	GO:0008559
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-6 USP30 ADAM19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24 PRSS48	1.46e-04	430	133	11	GO:0004175
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	GABRP ABCC1 SLC22A11 ABCC6 GLRB ABCC2 SLC37A4	1.50e-04	171	133	7	GO:0015103
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRP ABCC1 CACNA2D2 SLC22A11 KCNB2 ABCC6 KCNH3 SLC9A3 KCNG4 GLRB SCNN1A KCNN1 ABCC2 SLC37A4 SLC6A14	1.62e-04	758	133	15	GO:0015318
GeneOntologyMolecularFunction	sphingolipid transporter activity	ABCC1 ABCA1 ATP10A	3.03e-04	20	133	3	GO:0046624
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC1 ABCA1 ABCC6 ABCC2	3.16e-04	49	133	4	GO:0140359
GeneOntologyMolecularFunction	peptidase activity	ERVK-6 USP30 ADAM19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 USP31 ERVK-8 ERVK-19 ERVK-24 PRSS48 COPS5	4.32e-04	654	133	13	GO:0008233
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 POLG ERVK-7 ERVK-10 PARP16 ERVK-8	5.46e-04	152	133	6	GO:0016779
GeneOntologyMolecularFunction	transporter activity	GABRP ABCC1 ABCA1 CACNA2D2 SLC22A11 KCNB2 ATP10A ABCC6 SLC22A12 KCNH3 SLC9A3 KCNG4 GLRB NPC1L1 SCNN1A KCNN1 ABCC2 SLC37A4 SLC6A14	9.03e-04	1289	133	19	GO:0005215
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM3 ACSM5	1.20e-03	8	133	2	GO:0004321
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCA1 ATP10A	1.20e-03	8	133	2	GO:0090554
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC1 ABCC6 ABCC2	1.49e-03	34	133	3	GO:0042910
GeneOntologyMolecularFunction	gated channel activity	GABRP CACNA2D2 KCNB2 KCNH3 KCNG4 GLRB SCNN1A KCNN1	1.81e-03	334	133	8	GO:0022836
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.92e-03	79	133	4	GO:0004521
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRP ABCC1 ABCA1 CACNA2D2 SLC22A11 KCNB2 ABCC6 SLC22A12 KCNH3 SLC9A3 KCNG4 GLRB SCNN1A KCNN1 ABCC2 SLC37A4 SLC6A14	2.18e-03	1180	133	17	GO:0022857
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 DNASE1	2.18e-03	136	133	5	GO:0004519
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM3 ACSM5	2.33e-03	11	133	2	GO:0031956
GeneOntologyMolecularFunction	zinc ion binding	ERVK-6 ZSWIM8 TRIM4 MARCHF9 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24 MARCHF11 MARCHF4 PNMA3	2.49e-03	891	133	14	GO:0008270
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.16e-06	13	134	4	GO:0015074
GeneOntologyBiologicalProcess	leukotriene transport	ABCC1 ABCC6 ABCC2	9.21e-06	7	134	3	GO:0071716
GeneOntologyCellularComponent	external side of plasma membrane	SIGLEC12 FCRL2 IL13RA2 ABCA1 ADAM19 SLC22A11 CLEC7A MUC16 CD1A CSF2RB CEACAM21 GLRB SCNN1A	3.01e-05	519	134	13	GO:0009897
GeneOntologyCellularComponent	apical plasma membrane	GABRP ABCC1 SLC22A11 ABCC6 SLC22A12 SLC9A3 CEACAM21 NPC1L1 SCNN1A ABCC2 MUC4 SLC6A14	7.20e-05	487	134	12	GO:0016324
GeneOntologyCellularComponent	cell surface	HYAL4 SIGLEC12 FCRL2 IL13RA2 ABCA1 ADAM19 SPTB SLC22A11 CLEC7A MUC16 CD1A SLC9A3 CSF2RB CEACAM21 GLRB SCNN1A STRC ABCC2 CNTN2	8.73e-05	1111	134	19	GO:0009986
GeneOntologyCellularComponent	apical part of cell	GABRP ABCC1 SLC22A11 ABCC6 CEP164 SLC22A12 SLC9A3 CEACAM21 NPC1L1 SCNN1A ABCC2 MUC4 SLC6A14	1.14e-04	592	134	13	GO:0045177
GeneOntologyCellularComponent	brush border membrane	SLC22A12 SLC9A3 NPC1L1 ABCC2 SLC6A14	1.95e-04	83	134	5	GO:0031526
GeneOntologyCellularComponent	cell projection membrane	SLC22A12 GPR161 SLC9A3 NPC1L1 SCNN1A ABCC2 MUC4 INPP5J MTMR9 SLC6A14	4.70e-04	431	134	10	GO:0031253
GeneOntologyCellularComponent	side of membrane	SIGLEC12 FCRL2 IL13RA2 ABCA1 ADAM19 SPTB SLC22A11 CLEC7A MUC16 CD1A CSF2RB CEACAM21 GLRB SCNN1A CNTN2	4.97e-04	875	134	15	GO:0098552
Domain	Multidrug-R_assoc	ABCC1 ABCC6 ABCC2	1.22e-06	4	127	3	IPR005292
Domain	MARCH-like	MARCHF9 MARCHF11 MARCHF4	1.68e-05	8	127	3	IPR033275
Domain	HDAC_interact	SIN3B SIN3A	4.59e-05	2	127	2	SM00761
Domain	Sin3_C	SIN3B SIN3A	4.59e-05	2	127	2	IPR031693
Domain	Sin3_corepress	SIN3B SIN3A	4.59e-05	2	127	2	PF08295
Domain	Sin3a_C	SIN3B SIN3A	4.59e-05	2	127	2	PF16879
Domain	HDAC_interact_dom	SIN3B SIN3A	4.59e-05	2	127	2	IPR013194
Domain	ZF_RING_CH	MARCHF9 MARCHF11 MARCHF4	4.87e-05	11	127	3	PS51292
Domain	RINGv	MARCHF9 MARCHF11 MARCHF4	4.87e-05	11	127	3	PF12906
Domain	PAH	SIN3B SIN3A	1.37e-04	3	127	2	IPR003822
Domain	-	SIN3B SIN3A	1.37e-04	3	127	2	1.20.1160.11
Domain	Period_circadian-like_C	PER3 PER2	1.37e-04	3	127	2	IPR022728
Domain	PAH	SIN3B SIN3A	1.37e-04	3	127	2	PS51477
Domain	Period_C	PER3 PER2	1.37e-04	3	127	2	PF12114
Domain	PAH	SIN3B SIN3A	1.37e-04	3	127	2	PF02671
Domain	ABC_transporter_CS	ABCC1 ABCA1 ABCC6 ABCC2	1.87e-04	42	127	4	IPR017871
Domain	Znf_RING-CH	MARCHF9 MARCHF11 MARCHF4	1.95e-04	17	127	3	IPR011016
Domain	RINGv	MARCHF9 MARCHF11 MARCHF4	1.95e-04	17	127	3	SM00744
Domain	ABC_tran	ABCC1 ABCA1 ABCC6 ABCC2	3.15e-04	48	127	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCC1 ABCA1 ABCC6 ABCC2	3.15e-04	48	127	4	PS50893
Domain	ABC_TRANSPORTER_1	ABCC1 ABCA1 ABCC6 ABCC2	3.41e-04	49	127	4	PS00211
Domain	ABC_transporter-like	ABCC1 ABCA1 ABCC6 ABCC2	3.69e-04	50	127	4	IPR003439
Domain	AAA	ABCC1 ABCA1 ABCC6 MDN1 ABCC2 DNAH11	4.55e-04	144	127	6	SM00382
Domain	AAA+_ATPase	ABCC1 ABCA1 ABCC6 MDN1 ABCC2 DNAH11	4.55e-04	144	127	6	IPR003593
Domain	PAS_fold_3	KCNH3 PER3 PER2	4.92e-04	23	127	3	IPR013655
Domain	PAS_3	KCNH3 PER3 PER2	4.92e-04	23	127	3	PF08447
Domain	PAS-assoc_C	KCNH3 PER3 PER2	5.60e-04	24	127	3	IPR000700
Domain	ABC_membrane	ABCC1 ABCC6 ABCC2	5.60e-04	24	127	3	PF00664
Domain	PAC	KCNH3 PER3 PER2	7.12e-04	26	127	3	IPR001610
Domain	PAC	KCNH3 PER3 PER2	7.12e-04	26	127	3	PS50113
Domain	PAC	KCNH3 PER3 PER2	7.12e-04	26	127	3	SM00086
Domain	Endo/exonuclease/phosphatase	CWH43 DNASE1 INPP5J	7.97e-04	27	127	3	IPR005135
Domain	ABC_TM1F	ABCC1 ABCC6 ABCC2	8.88e-04	28	127	3	PS50929
Domain	ABC1_TM_dom	ABCC1 ABCC6 ABCC2	8.88e-04	28	127	3	IPR011527
Domain	EGF_LAM_2	CELSR2 MEGF8 ATRNL1	1.09e-03	30	127	3	PS50027
Domain	EGF_LAM_1	CELSR2 MEGF8 ATRNL1	1.09e-03	30	127	3	PS01248
Domain	PAS	KCNH3 PER3 PER2	1.32e-03	32	127	3	SM00091
Domain	PAS	KCNH3 PER3 PER2	1.58e-03	34	127	3	PS50112
Domain	PAS	KCNH3 PER3 PER2	1.58e-03	34	127	3	IPR000014
Domain	EGF_Lam	CELSR2 MEGF8 ATRNL1	1.71e-03	35	127	3	SM00180
Domain	-	SIGLEC12 FCRL2 IL13RA2 IL20RB TGM5 CD1A PTPRB CSF2RB CEACAM21 CD101 FLRT1 CNTN2	1.89e-03	663	127	12	2.60.40.10
Domain	Interfer-bind	IL20RB CSF2RB	1.99e-03	10	127	2	PF09294
Domain	Interferon/interleukin_rcp_dom	IL20RB CSF2RB	1.99e-03	10	127	2	IPR015373
Domain	Laminin_EGF	CELSR2 MEGF8 ATRNL1	2.18e-03	38	127	3	IPR002049
Domain	FN3	IL13RA2 IL20RB PTPRB CSF2RB FLRT1 CNTN2	2.41e-03	199	127	6	PS50853
Domain	IL6Ra-bind	IL13RA2 CSF2RB	2.42e-03	11	127	2	PF09240
Domain	TypeI_recpt_CBD	IL13RA2 CSF2RB	2.42e-03	11	127	2	IPR015321
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10 ERVK-24	2.44e-10	4	139	4	10469592
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	7.34e-10	12	139	5	14557543
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-21 ERVK-19	1.22e-09	5	139	4	12629516
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	4.43e-09	94	139	8	21542922
Pubmed	Expression and localization of ATP binding cassette (ABC) family of drug transporters in gastric hepatoid adenocarcinomas.	ABCC1 ABCC6 ABCC2	6.25e-08	3	139	3	18439156
Pubmed	Molecular physiology of renal organic anion transporters.	ABCC1 ABCA1 SLC22A12 ABCC2	1.70e-07	13	139	4	16403838
Pubmed	The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice.	PER3 PER2 SCNN1A	2.49e-07	4	139	3	19587447
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10 ERVK-19	2.49e-07	4	139	3	7983737
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-10 ERVK-24	7.16e-07	18	139	4	18664271
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-9 ERVK-19	1.24e-06	6	139	3	15063128
Pubmed	Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.	ABCC1 ABCC6 ABCC2	3.45e-06	8	139	3	15802388
Pubmed	Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.	ABCA1 ACSM3 CELSR2 NPC1L1 ABCC2	6.97e-06	66	139	5	20679960
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-21 ERVK-19	7.34e-06	10	139	3	12970426
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	MED13L EPG5 MCTP1 ATRNL1 MRNIP	9.99e-06	71	139	5	33541421
Pubmed	Dopamine adjusts the circadian gene expression of Per2 and Per3 in human dermal fibroblasts from ADHD patients.	PER3 PER2	1.59e-05	2	139	2	34275001
Pubmed	Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection.	ABCC1 ABCC2	1.59e-05	2	139	2	29976647
Pubmed	Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects.	SLC22A11 SLC22A12	1.59e-05	2	139	2	24360580
Pubmed	Clinical impact of ABCC1 and ABCC2 genotypes and haplotypes in mediating imatinib resistance among chronic myeloid leukaemia patients.	ABCC1 ABCC2	1.59e-05	2	139	2	25060527
Pubmed	Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects.	ABCC1 ABCC2	1.59e-05	2	139	2	11266082
Pubmed	Possible Association of PER2/PER3 Variable Number Tandem Repeat Polymorphism Variants with Susceptibility and Clinical Characteristics in Pancreatic Cancer.	PER3 PER2	1.59e-05	2	139	2	33393850
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.59e-05	2	139	2	9060628
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.59e-05	2	139	2	9460924
Pubmed	The mammalian Sin3 proteins are required for muscle development and sarcomere specification.	SIN3B SIN3A	1.59e-05	2	139	2	20956564
Pubmed	A novel association of two non-synonymous polymorphisms in PER2 and PER3 genes with specific diurnal preference subscales.	PER3 PER2	1.59e-05	2	139	2	23969301
Pubmed	Molecular identification of a renal urate anion exchanger that regulates blood urate levels.	SLC22A11 SLC22A12	1.59e-05	2	139	2	12024214
Pubmed	Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum.	ABCC1 ABCC6	1.59e-05	2	139	2	10835642
Pubmed	Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS-sorted peripheral blood CD4+, CD8+, CD19+, and CD56+ cells.	ABCC1 ABCC2	1.59e-05	2	139	2	12890151
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	1.59e-05	2	139	2	23544943
Pubmed	Variants in the circadian clock genes PER2 and PER3 associate with familial sleep phase disorders.	PER3 PER2	1.59e-05	2	139	2	38695651
Pubmed	Multidrug resistance-associated proteins are involved in the transport of the glutathione conjugates of the ultimate carcinogen of benzo[a]pyrene in human Caco-2 cells.	ABCC1 ABCC2	1.59e-05	2	139	2	22899102
Pubmed	Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter.	ABCC1 ABCC6	1.59e-05	2	139	2	10811882
Pubmed	Differential Complex Formation via Paralogs in the Human Sin3 Protein Interaction Network.	SIN3B SIN3A	1.59e-05	2	139	2	32467258
Pubmed	SIN3A and SIN3B differentially regulate breast cancer metastasis.	SIN3B SIN3A	1.59e-05	2	139	2	27780928
Pubmed	Metallothionein blocks oxidative DNA damage in vitro.	ABCC1 ABCC2	1.59e-05	2	139	2	22914987
Pubmed	Multidrug resistance proteins do not predict benefit of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: International Adjuvant Lung Cancer Trial Biologic Program.	ABCC1 ABCC2	1.59e-05	2	139	2	17606722
Pubmed	Distinct functions of Period2 and Period3 in the mouse circadian system revealed by in vitro analysis.	PER3 PER2	1.59e-05	2	139	2	20072700
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DCAF1 MED13L EPG5 USP31 KIDINS220 PER2 MEGF8 RHOBTB2 MARCHF4	4.05e-05	407	139	9	12693553
Pubmed	Expression profiles of PERIOD1, 2, and 3 in peripheral blood mononuclear cells from older subjects.	PER3 PER2	4.75e-05	3	139	2	19013183
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	4.75e-05	3	139	2	23053434
Pubmed	Contribution of child ABC-transporter genetics to prenatal MeHg exposure and neurodevelopment.	ABCC1 ABCC2	4.75e-05	3	139	2	35654246
Pubmed	A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light.	PER3 PER2	4.75e-05	3	139	2	9428527
Pubmed	Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice.	PER3 PER2	4.75e-05	3	139	2	26781276
Pubmed	Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.	PER3 PER2	4.75e-05	3	139	2	9427249
Pubmed	Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes.	ABCC1 ABCC2	4.75e-05	3	139	2	17890284
Pubmed	The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.	ABCC1 ABCC2	4.75e-05	3	139	2	12628490
Pubmed	Association between polymorphisms in period genes and bone density in postmenopausal Korean women.	PER3 PER2	4.75e-05	3	139	2	24678593
Pubmed	Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury.	ABCC1 ABCC2	4.75e-05	3	139	2	23896815
Pubmed	Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.	ABCC1 ABCC2	4.75e-05	3	139	2	18799096
Pubmed	For whom the circadian clock ticks? Investigation of PERIOD and CLOCK gene variants in bipolar disorder.	PER3 PER2	4.75e-05	3	139	2	34112033
Pubmed	VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context.	ITSN1 PER2	4.75e-05	3	139	2	29199069
Pubmed	Photic entrainment of period mutant mice is predicted from their phase response curves.	PER3 PER2	4.75e-05	3	139	2	20826680
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	4.75e-05	3	139	2	30236127
Pubmed	Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock.	PER3 PER2	4.75e-05	3	139	2	11395012
Pubmed	mPeriod2 Brdm1 and other single Period mutant mice have normal food anticipatory activity.	PER3 PER2	4.75e-05	3	139	2	29138421
Pubmed	The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor Alien.	SIN3B SIN3A	4.75e-05	3	139	2	15173382
Pubmed	A time memory engram embedded in a light-entrainable circadian clock.	PER3 PER2	4.75e-05	3	139	2	37951213
Pubmed	The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis.	SIN3B SIN3A	4.75e-05	3	139	2	22101514
Pubmed	Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity.	PER3 PER2	4.75e-05	3	139	2	12032351
Pubmed	Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.	PER3 PER2	4.75e-05	3	139	2	23606611
Pubmed	Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.	MUC16 MUC4	4.75e-05	3	139	2	17592322
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	4.75e-05	3	139	2	10516026
Pubmed	Function of prokaryotic and eukaryotic ABC proteins in lipid transport.	ABCC1 ABCA1	4.75e-05	3	139	2	15749056
Pubmed	Evidence for a role of PDZ domain-containing proteins to mediate hypophosphatemia in calcium stone formers.	SLC22A12 SLC9A3	4.75e-05	3	139	2	29126251
Pubmed	Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.	ABCC1 ABCC6	4.75e-05	3	139	2	17845218
Pubmed	Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers.	PER3 PER2	4.75e-05	3	139	2	15790588
Pubmed	Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function.	PER3 PER2	4.75e-05	3	139	2	22331899
Pubmed	NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity.	ABCC1 ABCC2	4.75e-05	3	139	2	16330681
Pubmed	Aberrant expression of Per1, Per2 and Per3 and their prognostic relevance in non-small cell lung cancer.	PER3 PER2	4.75e-05	3	139	2	25550826
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-9	4.75e-05	3	139	2	9971820
Pubmed	Inter-individual differences in habitual sleep timing and entrained phase of endogenous circadian rhythms of BMAL1, PER2 and PER3 mRNA in human leukocytes.	PER3 PER2	4.75e-05	3	139	2	18517031
Pubmed	Sin3 interacts with Foxk1 and regulates myogenic progenitors.	SIN3B SIN3A	4.75e-05	3	139	2	22476904
Pubmed	A flexible summary statistics-based colocalization method with application to the mucin cystic fibrosis lung disease modifier locus.	MUC4 SLC6A14	4.75e-05	3	139	2	35065708
Pubmed	A light-independent oscillatory gene mPer3 in mouse SCN and OVLT.	PER3 PER2	4.75e-05	3	139	2	9707434
Pubmed	The COP9 signalosome controls ubiquitinylation of ABCA1.	ABCA1 COPS5	4.75e-05	3	139	2	19268428
Pubmed	Intracellular calcium mobilization induces period genes via MAP kinase pathways in NIH3T3 cells.	PER3 PER2	4.75e-05	3	139	2	11959112
Pubmed	Comparing expression levels of PERIOD genes PER1, PER2 and PER3 in chronic insomnia patients and medical staff working in the night shift.	PER3 PER2	4.75e-05	3	139	2	32805476
Pubmed	Sleep rhythmicity and homeostasis in mice with targeted disruption of mPeriod genes.	PER3 PER2	4.75e-05	3	139	2	15031135
Pubmed	A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.	SIN3B SIN3A	4.75e-05	3	139	2	9139820
Pubmed	Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells.	SIN3B SIN3A	4.75e-05	3	139	2	20547842
Pubmed	The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15.	PER3 PER2	4.75e-05	3	139	2	29186676
Pubmed	Nuclear export of mammalian PERIOD proteins.	PER3 PER2	4.75e-05	3	139	2	11591712
Pubmed	Period determination in the food-entrainable and methamphetamine-sensitive circadian oscillator(s).	PER3 PER2	4.75e-05	3	139	2	22891330
Pubmed	The role of phosphorylation and degradation of hPER protein oscillation in normal human fibroblasts.	PER3 PER2	4.75e-05	3	139	2	14712925
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC4	4.75e-05	3	139	2	35879412
Pubmed	Pseudoxanthoma elasticum: Point mutations in the ABCC6 gene and a large deletion including also ABCC1 and MYH11.	ABCC1 ABCC6	4.75e-05	3	139	2	11439001
Pubmed	Molecular analysis of avian circadian clock genes.	PER3 PER2	4.75e-05	3	139	2	10891604
Pubmed	Period Family of Clock Genes as Novel Predictors of Survival in Human Cancer: A Systematic Review and Meta-Analysis.	PER3 PER2	4.75e-05	3	139	2	32849922
Pubmed	Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.	ABCC1 ABCC2	4.75e-05	3	139	2	17494643
Pubmed	The multidrug resistance protein family.	ABCC1 ABCC2	4.75e-05	3	139	2	10581366
Pubmed	Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.	ABCC1 ABCC2	4.75e-05	3	139	2	10581368
Pubmed	Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).	MUC16 MUC4	4.75e-05	3	139	2	27483328
Pubmed	A family of drug transporters: the multidrug resistance-associated proteins.	ABCC1 ABCC2	4.75e-05	3	139	2	10944550
Pubmed	MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.	MUC16 MUC4	4.75e-05	3	139	2	24204560
Pubmed	Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis.	SLC9A3 SLC6A14	4.75e-05	3	139	2	22466613
Pubmed	Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway.	PER3 PER2	4.75e-05	3	139	2	29269828
Pubmed	Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.	MUC16 MUC4	4.75e-05	3	139	2	24939955
Pubmed	Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease.	ABCC1 ABCC2	4.75e-05	3	139	2	25425682
Pubmed	Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.	ABCA1 NPC1L1	4.75e-05	3	139	2	15604518
Pubmed	PER2 rs2304672, CLOCK rs1801260, and PER3 rs57875989 polymorphisms are not associated with juvenile myoclonic epilepsy.	PER3 PER2	4.75e-05	3	139	2	24892753
Pubmed	The complex relationship between the light-entrainable and methamphetamine-sensitive circadian oscillators: evidence from behavioral studies of Period-mutant mice.	PER3 PER2	4.75e-05	3	139	2	23869717
Interaction	PDZK1 interactions	ABCA1 SLC22A11 SLC22A12 SLC9A3 GUCY2C ABCC2	3.71e-06	66	127	6	int:PDZK1
Cytoband	16p13.1	ABCC1 ABCC6	5.36e-05	4	138	2	16p13.1
GeneFamily	Ring finger proteins\|Membrane associated ring-CH-type fingers	MARCHF9 MARCHF11 MARCHF4	2.32e-05	11	96	3	60
GeneFamily	ATP binding cassette subfamily C	ABCC1 ABCC6 ABCC2	3.99e-05	13	96	3	807
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	SIN3B SIN3A	9.80e-04	9	96	2	1306
GeneFamily	Potassium voltage-gated channels	KCNB2 KCNH3 KCNG4	1.24e-03	40	96	3	274
GeneFamily	Fibronectin type III domain containing	IL20RB PTPRB CSF2RB FLRT1 CNTN2	1.63e-03	160	96	5	555
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	SIN3B SIN3A	1.78e-03	12	96	2	1243
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP16 ZC3HAV1	3.60e-03	17	96	2	684
Coexpression	GSE3720_UNSTIM_VS_LPS_STIM_VD2_GAMMADELTA_TCELL_DN	ITSN1 CLEC7A PER3 ATRNL1 SYPL1 MUC4 ERICH6	1.23e-05	153	131	7	M6338
Coexpression	PATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_93YO_VZV_CHALLENGE_6HR_UP	ABCA1 ADAM19 CLEC7A SIN3A MED13L TASOR2 MCTP1 CSF2RB MTMR9	1.64e-05	291	131	9	M41002
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP30 CACNA2D2 MDN1 SCNN1A TMEM131 INPP5J MTMR9	8.44e-07	175	130	7	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	ABCA1 ITSN1 LGALS3BP PER3 ARHGAP12 ACSM5 TMEM86A	1.31e-06	187	130	7	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	Parenchymal-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 MUC4 SLC6A14	2.06e-06	200	130	7	4e5b6cb014d9bcb58e13c7511c86c43e27c496e4
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 USP31 GPR161 SYCP2 DACT3 MUC4	6.36e-06	155	130	6	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRP MUC16 PER2 TAS1R1 MUC4 SLC6A14	7.36e-06	159	130	6	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAM19 CLEC7A SYCP2 CSF2RB CD101 SCNN1A	8.19e-06	162	130	6	ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAM19 CLEC7A SYCP2 CSF2RB CD101 SCNN1A	8.19e-06	162	130	6	4e7e565091bce227d794a36af2e5dfc4a791efad
ToppCell	368C-Epithelial_cells-Epithelial-A_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	8.79e-06	164	130	6	85f53d184fa70e3eb1af655807f32b17ddbfb304
ToppCell	368C-Epithelial_cells-Epithelial-A_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	8.79e-06	164	130	6	144ba070a1ede71684224cc6d4ead3b7e6a7b4c6
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRP MUC16 PER2 SCNN1A MUC4 SLC6A14	1.45e-05	179	130	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3_(Neuron.Gad1Gad2.Cplx3)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRR19 SCNN1A TAS1R1 ABCC2	1.75e-05	53	130	4	9c6aba539d540211b2309da1af6a531f3275a49d
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3_(Neuron.Gad1Gad2.Cplx3)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRR19 SCNN1A TAS1R1 ABCC2	1.75e-05	53	130	4	846e031024ad3a4f5c6640b61cf4a0e69dbbcd1c
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	1.85e-05	187	130	6	11670a85db87cbb3e78022a589632173604b0940
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	1.85e-05	187	130	6	0277d4e54bd4d48f30241c2951a569209423fee8
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	PDE3B MED13L TASOR2 EPG5 TMEM131 ZC3HAV1	1.91e-05	188	130	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GABRP SYT12 MUC16 TMCO2 MUC4 SLC6A14	1.91e-05	188	130	6	07705bed928683470a52c8ccfa40ffb9a0971318
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	1.97e-05	189	130	6	6f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	1.97e-05	189	130	6	926b5fa3064b501a57ba78583e8af33532add455
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	2.02e-05	190	130	6	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	368C-Epithelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	2.02e-05	190	130	6	459811e88d3001816c2d89034e0921c24918c17f
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HYAL4 FFAR2 CLEC7A LINC00528 MCTP1 CSF2RB	2.02e-05	190	130	6	212f0d9defcc3174e225cc3d90e7814e238794b6
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	CACNA2D2 ABCC6 RHOBTB2 SCNN1A DMBT1 SLC6A14	2.09e-05	191	130	6	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Nasal_Brush\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	GABRP MUC16 IL20RB SCNN1A MUC4 SLC6A14	2.34e-05	195	130	6	7509b980b6b293df02bec619ef5b83a6c7b49c03
ToppCell	Monocytes-M2-like_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ABCA1 ITSN1 CLEC7A LGALS3BP PER3 TMEM86A	2.34e-05	195	130	6	10fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell	critical-Epithelial-Secretory\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GABRP ADGRG1 LGALS3BP PER2 SCNN1A SLC6A14	2.41e-05	196	130	6	7da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCell	NS-critical-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GABRP IL20RB ADGRG1 LGALS3BP SCNN1A SLC6A14	2.48e-05	197	130	6	a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GABRP MUC16 LGALS3BP SCNN1A MUC4 SLC6A14	2.55e-05	198	130	6	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GABRP TMEM191C MUC16 PER2 SCNN1A MUC4	2.55e-05	198	130	6	1fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCell	mild-Neutrophil\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GABRP FFAR2 CLEC7A ALPK1 SYCP2 CSF2RB	2.63e-05	199	130	6	ca319976a7d2576186d0a98cdc93e4c2d5fe8a05
ToppCell	moderate-Epithelial-Secretory-diff\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GABRP MUC16 LGALS3BP SCNN1A MUC4 SLC6A14	2.70e-05	200	130	6	6f29ef9dcf126c5c19386f6aa9a20c38a2c8ccc8
ToppCell	moderate-Epithelial\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GABRP MUC16 LGALS3BP SCNN1A MUC4 SLC6A14	2.70e-05	200	130	6	095783c9b75113ae350c2d5fb1195d71b41fa695
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT2-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CACNA2D2 ACSM3 RHOBTB2 SCNN1A DMBT1 SLC6A14	2.70e-05	200	130	6	cf1991853e10c562edae9a0d71a209f35b07db80
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory-diff\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GABRP MUC16 LGALS3BP SCNN1A MUC4 SLC6A14	2.70e-05	200	130	6	8f179b5768fd504af6dd6f6749a0bed7b689e77f
ToppCell	Biopsy_Other_PF-Epithelial\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CACNA2D2 RHOBTB2 SCNN1A DMBT1 MUC4 SLC6A14	2.70e-05	200	130	6	1ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA2D2 ACSM3 RHOBTB2 SCNN1A DMBT1 SLC6A14	2.70e-05	200	130	6	7618ae284625c5c121bcc00eb9f07e5b1e3adf23
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CACNA2D2 ACSM3 RHOBTB2 SCNN1A DMBT1 SLC6A14	2.70e-05	200	130	6	23b319bf7e5ae03e5baa777c951da9bfc97cca8c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GTSF1 SYT12 ITIH3 ACSM3 MARCHF11	7.17e-05	147	130	5	989a48bda98fbff398985397a6b1189a4cbc80e7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GTSF1 SYT12 ITIH3 ACSM3 MARCHF11	7.17e-05	147	130	5	f6681c849c4c06154548bd29a094f202d1c946c2
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM19 CLEC7A SYCP2 MCTP1 CSF2RB	7.89e-05	150	130	5	6e806a028c0519489151c181d9907e05289e27e0
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC6 ITIH3 ACSM3 ABCC2 SLC37A4	9.49e-05	156	130	5	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	facs-Lung-EPCAM-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC7A SYCP2 CSF2RB SCNN1A PNMA3	1.04e-04	159	130	5	baf843dc44b072504eb1d28de55b1ee67aeec32b
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC7A SYCP2 CSF2RB SCNN1A PNMA3	1.04e-04	159	130	5	9eb78202b9a4e8217f00e64d5142ed28c00abd04
ToppCell	droplet-Lung-nan-21m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM19 CLEC7A SYCP2 CD101 SCNN1A	1.04e-04	159	130	5	555ebf719504980c7584203a3ee1ba5779ab76d8
ToppCell	droplet-Lung-nan-21m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM19 CLEC7A SYCP2 CD101 SCNN1A	1.04e-04	159	130	5	a6a5cded6da02a112e04c2c71ce08cc27c1c5002
ToppCell	(05)_Ciliated-(1)_24hpi\|(05)_Ciliated / shred by cell type and Timepoint	CWH43 POLG DMBT1 ERICH6	1.29e-04	88	130	4	76959e7e3f6fae07c9881a29c28ba847be406694
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 IARS1 RHOBTB2 KCNN1 SLC6A14	1.31e-04	167	130	5	dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCell	normal_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	SIGLEC12 FFAR2 MEGF8 PARP16 EIF4E3	1.31e-04	167	130	5	820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GDPD5 MARCHF11 MARCHF4 INPP5J HRH3	1.31e-04	167	130	5	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GDPD5 MARCHF11 MARCHF4 INPP5J HRH3	1.31e-04	167	130	5	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC16 KCNH3 KCNN1 STRC DNAH11	1.31e-04	167	130	5	8b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GTSF1 ZNF285 LGALS3BP ACSM3 TMCO2	1.34e-04	168	130	5	eba865465feb0f42055bb8f98946050eeb03d177
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FFAR2 IL20RB KCNB2 GUCY2C MARCHF4	1.34e-04	168	130	5	0f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCell	Ionocyte\|World / Class top	ABCC6 SYCP2 ACSM3 KIDINS220 XKR5	1.42e-04	170	130	5	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	15-Airway-Epithelial-Club-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	GABRP MUC16 ADGRG1 MUC4 SLC6A14	1.42e-04	170	130	5	1418031cc4b4a87a48621eb53a3c819cd713ddd0
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-club_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GABRP CWH43 ARHGAP12 SCNN1A MUC4	1.42e-04	170	130	5	6de3778e8257c3330db0780c59238ca501fe5059
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-club_cell-club_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GABRP CWH43 ARHGAP12 SCNN1A MUC4	1.42e-04	170	130	5	60887da674ef1a735bad618235608312d8de63d3
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	GABRP ADGRG1 TGM5 SYPL1 MUC4	1.46e-04	171	130	5	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GABRP MUC16 SCNN1A MUC4 SLC6A14	1.54e-04	173	130	5	d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRP MUC16 DMBT1 MUC4 SLC6A14	1.54e-04	173	130	5	176b956e71d98e8275d698b39437fc326e5fe449
ToppCell	droplet-Heart-4Chambers-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG1 GDPD5 PTPRB ARAP3 SYPL1	1.54e-04	173	130	5	9a04271c51fae34f547db3206f9ff5857686e45c
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GUCY2C NPC1L1 DMBT1 STRC PNMA3	1.63e-04	175	130	5	6759d200a133034756de9cdf2d5daceca927aac9
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp-Endothelial_Tip.Dcn.Mgp-Penk_(Penk)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FFAR2 TGM5 GUCY2C SLC6A14	1.66e-04	94	130	4	8fb9adf0db3b0007204716869d895700cbdc6231
ToppCell	(03)_Secretory\|World / shred by cell type and Timepoint	GABRP MUC16 LGALS3BP DMBT1 MUC4	1.67e-04	176	130	5	cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GABRP MUC16 CELSR2 MUC4 SLC6A14	1.67e-04	176	130	5	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALPK1 SLC22A12 TTLL6 SCNN1A DNAH11	1.71e-04	177	130	5	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GABRP ARGFX MUC16 MUC4 SLC6A14	1.76e-04	178	130	5	9a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GABRP ARGFX MUC16 MUC4 SLC6A14	1.76e-04	178	130	5	b413a634283550fa224db7d0d05956e3f64694a1
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GABRP ARGFX MUC16 MUC4 SLC6A14	1.76e-04	178	130	5	49a2271718637522f74334068d252963ee13b1ce
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A12 TTLL6 SCNN1A ERICH6 DNAH11	1.76e-04	178	130	5	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GABRP ARGFX MUC16 MUC4 SLC6A14	1.76e-04	178	130	5	19b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A12 TTLL6 SCNN1A ERICH6 DNAH11	1.76e-04	178	130	5	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG1 PTPRB ARAP3 MCTP1 PER3	1.81e-04	179	130	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	LGALS3BP RHOBTB2 SCNN1A DMBT1 SLC6A14	1.81e-04	179	130	5	466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	LGALS3BP RHOBTB2 SCNN1A DMBT1 SLC6A14	1.81e-04	179	130	5	f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SIN3B ADAM19 ADGRG1 USP31 ARAP3	1.85e-04	180	130	5	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	10x5'-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	ALPK1 GDPD5 CSF2RB TMEM131 DNASE1	1.90e-04	181	130	5	56fa77ae31f3b7de6e441a439c33a11353b6573a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 GDPD5 PTPRB ARAP3 KCNG4	1.95e-04	182	130	5	41b070085edba7a58b81c20aa4942d06f745acf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 GDPD5 PTPRB ARAP3 KCNG4	1.95e-04	182	130	5	5e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 GDPD5 PTPRB ARAP3 KCNG4	1.95e-04	182	130	5	b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC22A11 ABCC6 SLC22A12 SLC9A3 ABCC2	2.00e-04	183	130	5	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1\|TCGA-Thryoid / Sample_Type by Project: Shred V9	ADAM19 CLEC7A CSF2RB CD101 SLC6A14	2.00e-04	183	130	5	06e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRP CRISP2 ITIH3 CSF2RB SLC6A14	2.00e-04	183	130	5	9a2cd63af5f492d46ce80ca1536312e8ac0e7df4
ToppCell	10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DCAF1 SIGLEC12 ABCC1 EPG5 CSF2RB	2.00e-04	183	130	5	f9a3af96c0fb7d5c4d7df6db8b2c42e322418c08
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	CACNA2D2 RHOBTB2 SCNN1A DMBT1 SLC6A14	2.05e-04	184	130	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	mild-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PDE3B FFAR2 ALPK1 ARAP3 CSF2RB	2.05e-04	184	130	5	1a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG1 KCNG4 SCNN1A TMEM86A DNAH11	2.10e-04	185	130	5	af86e75096c1812ae27a78405355957ee8043d84
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ABCA1 MED13L ABCC6 ACSM3 ABCC2	2.10e-04	185	130	5	1d874608aa2062024323512f68889219471b2f00
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	FFAR2 ITSN1 ALPK1 ARAP3 PRR19	2.21e-04	187	130	5	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRP MUC16 SCNN1A DMBT1 MUC4	2.21e-04	187	130	5	71d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CWH43 CACNA2D2 LGALS3BP NPC1L1 MARCHF11	2.21e-04	187	130	5	b7689e7f6511920cd2beff27389555fddf685f61
ToppCell	Endothelial-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	LINC00528 PTPRB GLRB ACSM5 DNASE1	2.27e-04	188	130	5	ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRP MUC16 SCNN1A MUC4 SLC6A14	2.27e-04	188	130	5	5901b276f2379abf486b8285957277e95f08464e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GABRP CELSR2 SCNN1A DMBT1 MUC4	2.32e-04	189	130	5	ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GABRP CELSR2 SCNN1A DMBT1 MUC4	2.32e-04	189	130	5	dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCell	COPD\|World / Disease state, Lineage and Cell class	PDE3B ADAM19 ATP10A LGALS3BP ZC3HAV1	2.32e-04	189	130	5	53577632683686dc493a5a3fdc01887ec5c320f2
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	CACNA2D2 RHOBTB2 SCNN1A DMBT1 SLC6A14	2.32e-04	189	130	5	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FFAR2 ADGRG1 KCNB2 SCNN1A MARCHF4	2.38e-04	190	130	5	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 SLC9A3 SCNN1A MUC4 SLC6A14	2.38e-04	190	130	5	23f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3B CWH43 ADGRG1 SCNN1A INPP5J	2.38e-04	190	130	5	c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 SLC9A3 SCNN1A MUC4 SLC6A14	2.38e-04	190	130	5	3c337374d89e69cc0a78e65a4a7e21db7b050fcd
Drug	fluorexon	ABCC1 ABCC6 ABCC2	7.76e-07	4	133	3	ctd:C007740
Drug	6-carboxyfluorescein	ABCC1 SLC22A11 ABCC2	1.93e-06	5	133	3	ctd:C024098
Drug	benzbromarone	ABCC1 SLC22A11 ABCC6 SLC22A12 ABCC2	2.37e-06	37	133	5	CID000002333
Drug	Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	PDE3B CACNA2D2 ALPK1 TEX13A ATP10A CEP164 CD1A ACSM3 SCNN1A	2.55e-06	198	133	9	5797_UP
Drug	Liothyronine [6893-02-3]; Up 200; 6.2uM; PC3; HT_HG-U133A	SYT12 POLG ITIH3 PTPRB ATRNL1 CD101 SCNN1A FLRT1 MUC4	2.66e-06	199	133	9	6602_UP
Drug	AC1NB6SN	ABCC1 ABCC6 ABCC2	3.85e-06	6	133	3	CID004488324
Drug	Nem-S-G	ABCC1 ABCC6 ABCC2	1.07e-05	8	133	3	CID000126950
Drug	calcein AM	ABCC1 ABCC6 ABCC2	1.07e-05	8	133	3	ctd:C085925
Drug	GF120918	ABCC1 IL17F ABCC6 ABCC2	1.08e-05	24	133	4	CID000119373
Drug	6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; PC3; HT_HG-U133A	DCAF1 CRISP2 ADGRG1 HHLA1 RFX2 CD1A PTPRB RHOBTB2	1.83e-05	193	133	8	4477_UP
Drug	Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; PC3; HT_HG-U133A	SYT12 SPTB ALPK1 RFX2 ATP10A MCTP1 CEACAM21 MRNIP	1.83e-05	193	133	8	2055_UP
Drug	Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A	CACNA2D2 POLG ADGRG1 OR2B6 CEP164 CEACAM21 NFRKB KCNN1	2.20e-05	198	133	8	5387_UP
Drug	Phensuximide [86-34-0]; Up 200; 21.2uM; HL60; HT_HG-U133A	POLG ALPK1 GDPD5 ACSM3 RHOBTB2 NFRKB SCNN1A MRNIP	2.20e-05	198	133	8	2960_UP
Drug	Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; HL60; HG-U133A	ABCC1 ZSWIM8 ALPK1 ATP10A GDPD5 CD1A CELSR2 NFRKB	2.28e-05	199	133	8	2045_DN
Drug	Probenecid	ABCC1 SLC22A11 ABCC6 SLC22A12 ABCC2	2.45e-05	59	133	5	ctd:D011339
Drug	Sulfinpyrazone	ABCC1 SLC22A12 ABCC2	3.11e-05	11	133	3	ctd:D013442
Drug	Sulfinpyrazone	ABCC1 ABCC2	3.39e-05	2	133	2	DB01138
Drug	glutathione-BPDE conjugate	ABCC1 ABCC2	3.39e-05	2	133	2	ctd:C113118
Drug	robinetin	ABCC1 ABCC2	3.39e-05	2	133	2	ctd:C040014
Drug	Fluo-3	ABCC1 ABCC2	3.39e-05	2	133	2	ctd:C059715
Drug	Leukotriene C4	ABCC1 CLEC7A ABCC6 ABCC2	5.06e-05	35	133	4	ctd:D017997
Drug	harmol sulfate	ABCC1 ABCC6 ABCC2	5.34e-05	13	133	3	CID005488302
Drug	tetramethylrosamine	ABCC1 ABCC6 ABCC2	6.77e-05	14	133	3	CID000443313
Drug	tetraethylammonium	SLC22A11 KCNB2 KCNH3 ACSM3 GUCY2C SCNN1A KCNN1 HRH3	7.62e-05	236	133	8	CID000005413
Drug	MX-68	ABCC1 ABCC6 ABCC2	8.42e-05	15	133	3	CID006918310
Drug	PAK-104P	ABCC1 ABCC6 ABCC2	8.42e-05	15	133	3	CID000131368
Drug	cimetidine	ABCC1 SLC22A11 CYP39A1 ABCC6 SLC22A12 ABCC2 HRH3	8.93e-05	179	133	7	CID000002756
Disease	Congenital secretory diarrhea, sodium type (disorder)	SLC9A3 GUCY2C	5.07e-05	3	122	2	C0267663
Disease	Intestinal Obstruction	SLC9A3 SLC6A14	5.07e-05	3	122	2	C0021843
Disease	Advanced Sleep-Phase Syndrome, Familial	PER3 PER2	5.07e-05	3	122	2	C1858496
Disease	advanced sleep phase syndrome (is_implicated_in)	PER3 PER2	1.01e-04	4	122	2	DOID:0050628 (is_implicated_in)
Disease	CYSTIC FIBROSIS MODIFIER 1	SLC9A3 SLC6A14	1.01e-04	4	122	2	C1859047
Disease	CD166 antigen measurement	ABCC1 ABCC6	1.01e-04	4	122	2	EFO_0020245
Disease	chronic mucocutaneous candidiasis (is_implicated_in)	CLEC7A IL17F	1.68e-04	5	122	2	DOID:2058 (is_implicated_in)
Disease	Candidiasis, Chronic Mucocutaneous	CLEC7A IL17F	2.52e-04	6	122	2	C0006845
Disease	X-17676 measurement	ACSM3 ACSM5	4.67e-04	8	122	2	EFO_0800785
Disease	cystic fibrosis, lung disease severity measurement	SLC9A3 MUC4	5.99e-04	9	122	2	EFO_0007744, MONDO_0009061
Disease	Proteinuria	MUC16 SCNN1A DNASE1	7.54e-04	43	122	3	C0033687
Disease	Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement	KCNB2 DNAH11	9.10e-04	11	122	2	EFO_0009923
Disease	Diarrhea	SLC9A3 GUCY2C	9.10e-04	11	122	2	C0011991
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRP SIN3B SIN3A	1.11e-03	49	122	3	DOID:0060037 (implicated_via_orthology)
Disease	antihyperlipidemic drug use measurement	ABCA1 CELSR2 NPC1L1 DNAH11	1.35e-03	115	122	4	EFO_0803367
Disease	Peripheral Nervous System Diseases	ABCC1 ABCA1 RHOBTB2	1.47e-03	54	122	3	C4721453
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	ABCA1 CELSR2 NPC1L1 DNAH11	1.58e-03	120	122	4	EFO_0004611, EFO_0004639
Disease	low density lipoprotein particle size measurement	ABCA1 CELSR2 FLRT1	1.80e-03	58	122	3	EFO_0008593
Disease	cholesteryl ester measurement, low density lipoprotein cholesterol measurement	ABCA1 ITIH3 CELSR2 NPC1L1	1.89e-03	126	122	4	EFO_0004611, EFO_0010351
Disease	Colorectal Carcinoma	ABCC1 ABCA1 ADAM19 KCNB2 ABCC6 ARAP3 GUCY2C SNX8 ABCC2	2.61e-03	702	122	9	C0009402
Disease	Microcephaly	IARS1 SIN3A DYNC1I2	2.72e-03	67	122	3	C0025958
Disease	brain infarction, neuritic plaque measurement, Lewy body dementia, cerebral amyloid angiopathy, neurofibrillary tangles measurement	KCNB2 ATP10A	3.71e-03	22	122	2	EFO_0004277, EFO_0006790, EFO_0006792, EFO_0006797, EFO_0006798
Disease	Bronchiectasis	SCNN1A DNAH11	3.71e-03	22	122	2	C0006267
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	ABCA1 ITIH3 CELSR2 NPC1L1	3.80e-03	153	122	4	EFO_0004611, EFO_0020944

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSNPLLRWWATSASN	nan	116	A8MVM7
LWNKYWVNTLSSSSL	COPS5	241	Q92905
WNWSNSITSSPFVSF	ERICH6	521	Q7L0X2
LATPTQVWFAWTVLN	EPG5	1226	Q9HCE0
EAWTSAVGKWFSPLS	ARAP3	776	Q8WWN8
VPTVADFLNLAWWTS	CACNA2D2	961	Q9NY47
VSENPYSTLWSFLSW	ADAM19	271	Q9H013
TASLLTFWNAPTTAW	CEACAM21	21	Q3KPI0
TFWNAPTTAWLFIAS	CEACAM21	26	Q3KPI0
LDNSILWFSWFISSL	ABCA1	676	O95477
PSNWAWNSTFTESST	ARGFX	186	A6NJG6
FWNSLGWSFSVLTEP	LINC00528	131	Q8N1L1
DFPAQVALTSSQIWW	DNAH11	1736	Q96DT5
VKAAWTLFSAWPNGS	ACSM5	276	Q6NUN0
WLCPSSASNLWLYTS	CELSR2	56	Q9HCU4
SSDPTSWSSAIQSWY	CRISP2	101	P16562
SLPTFSLLNWISSWS	ATP10A	1431	O60312
SQNSSSSSVWWLKSP	ALPK1	921	Q96QP1
SSSVWWLKSPAFSSG	ALPK1	926	Q96QP1
TQSWTAVTPQQTWAS	C18orf25	371	Q96B23
SSWAETTYWISPQGI	IL13RA2	121	Q14627
WSLLFQPGWLSFSSQ	GUCY2C	11	P25092
ASQSSPWPRATAFWT	KCNH3	981	Q9ULD8
WSPIQQVTATSSKWA	MRNIP	216	Q6NTE8
NAITSWLWDLTTSLP	MUC16	2046	Q8WXI7
STIWWSDTLSTALSP	MUC4	426	Q99102
LTSATWSQPLSALWG	DCAF1	1151	Q9Y4B6
KATWLFSWLDSPALQ	DNAJC14	361	Q6Y2X3
TTDSLWFNWSPASGD	PTPRB	1186	P23467
AASWVTGFSNSVWLS	OR2B6	146	P58173
ASWINLTEQWPYRTS	KIDINS220	966	Q9ULH0
FEVLTSSWRASPWDV	MDN1	3071	Q9NU22
SPWWRSIAVVFSSLN	FFAR2	251	O15552
KNTFNWTVPFLSWLA	MCTP1	906	Q6DN14
VSTAKAENLPQWFWS	MED13L	2101	Q71F56
SPTWSAFVTDSSWSA	LGALS3BP	411	Q08380
SSLNSWFSAAPNWAE	NFRKB	411	Q6P4R8
SLWSWVNQPSELSKF	MTMR9	456	Q96QG7
LWEQTSTPFVWGTTH	GTSF1	111	Q8WW33
LLVFSISSWIIAAWT	KCNN1	286	Q92952
EFTSIPASYWWAIIS	KCNG4	401	Q8TDN1
LFVTSSFDWTVKLWT	DYNC1I2	496	Q13409
TWDSNSSTIVFLCPW	CD1A	56	P06126
DTSWSSFINPWSRKI	PER2	411	O15055
ILDSSWSSFVNPWSR	PER3	351	P56645
WSSFVNPWSRKISFI	PER3	356	P56645
WITYQGFLSQWTLTT	RHOT1	356	Q8IXI2
ASFVWWVSFTSLGSL	PDE3B	226	Q13370
LAVAISPSAWYSWCS	POLG	211	P54098
NFSANTWESWDLSPA	MEGF8	261	Q7Z7M0
LAVYSILWSGWASNS	MT-ND1	111	P03886
GQWFLKTDPFWTASS	GDPD5	311	Q8WTR4
VVLSWLSFWINPDAS	GLRB	281	P48167
VAFIGSNLWLSAWTS	ABCC2	991	Q92887
SNLWLSAWTSDSKIF	ABCC2	996	Q92887
VATWQQSSLSLRWAS	NOP14	656	P78316
SLYTSHIWIPSSWCS	IL20RB	76	Q6UXL0
SSWTFWLDRSLPGAT	EIF4E3	51	Q8N5X7
SRSTSPWNYTVTWDP	IL17F	76	Q96PD4
VASISWLIWSSLSPS	MARCHF9	196	Q86YJ5
WLSSWAVLQGSSLLF	ARHGAP12	486	Q8IWW6
PKRASSQLSWFSSHW	PARP16	276	Q8N5Y8
SSWVDDFIDWLTPSS	NPC1L1	951	Q9UHC9
SSLSPSQFLQFKTWW	ERVK-10	356	P87889
SSLSPSQFLQFKTWW	ERVK-19	356	Q9YNA8
SSLLPSQFLQFKTWW	ERVK-21	356	P62683
SSLSPSQFLQFKTWW	ERVK-24	356	P63145
SSLSPSQFLQFKTWW	ERVK-6	356	Q7LDI9
SSLSPSQFLQFKTWW	ERVK-7	356	P63130
SSLSPSQFLQFKTWW	ERVK-8	356	P62685
SSLSPSQFLQFKTWW	ERVK-9	356	P63126
WSSTVPVFAALWFLN	SLC37A4	96	O43826
SSLSPSQFLQFKTWW	HERVK_113	356	P62684
TWSVALGSPQSHWLS	CSF2RB	151	P32927
IIWYFSPVSTNASWL	CD101	711	Q93033
DATKFTSIPASFWWA	KCNB2	361	Q92953
SPAALSRAWASSWES	DACT3	316	Q96B18
SQWSSIRLWTSPTFQ	DNASE1	201	P24855
TPNNWADFSSTWPTS	ITSN1	846	Q15811
NELSWLWNSSAALYP	HYAL4	246	Q2M3T9
LATSVTSWWSPQNIS	ADGRG1	136	Q9Y653
TSWWSPQNISLPSAA	ADGRG1	141	Q9Y653
WVFNIHSQSWSTKTP	ATRNL1	386	Q5VV63
WTFSSSSLSIKWDPV	CNTN2	921	Q02246
TSFWLLWANSAVNPV	HRH3	396	Q9Y5N1
SISWLIWSTFSPSAR	MARCHF4	251	Q9P2E8
IASVTWLLWSAFSPY	MARCHF11	256	A6NNE9
VSPSLETWATWLSFA	GPR161	301	Q8N6U8
LWASLSNAVPVAFWT	CYP39A1	271	Q9NYL5
WSSSPELQISAVWSE	FCRL2	156	Q96LA5
TWKATLPASSFRLSW	FLRT1	426	Q9NZU1
AHLAANSSLSWWSPG	GPR139	6	Q6DWJ6
ATQINSTTTDWWHPT	DMBT1	1741	Q9UGM3
AASVPFFAISLISWW	SLC22A11	261	Q9NSA0
WQLLDPNATATSWSE	SLC22A12	96	Q96S37
LGSQWSLWFGSSVLS	SCNN1A	551	P37088
VPSTFLVVLSWVSFW	GABRP	251	O00591
WVSFWISLDSVPART	GABRP	261	O00591
SSASFLSRITFWWIT	ABCC1	211	P33527
SSSLIVQAVTWWSGS	CWH43	101	Q9H720
STFQNWLPSTPATSW	PLIN4	1036	Q96Q06
TFLWLVSTSAWAKAL	SYPL1	161	Q16563
DFLNAATLWSSTWLS	TAS2R60	101	P59551
ADRQTWASISSVPWA	HHLA1	321	C9JL84
WASISSVPWAQTISE	HHLA1	326	C9JL84
AVSLWKLWTSGSFPS	SYT12	36	Q8IV01
PSWAALNSSTWGSLK	SNX8	271	Q9Y5X2
LSLSTVWNWIQASFL	TMCO2	16	Q7Z6W1
GAVSAWLWSLTSETT	TMEM191C	311	A6NGB0
TGAAFPSKATFWWVS	ABCC6	206	O95255
WLSFWNSKASSSDGP	RFX2	396	P48378
ITLWNRAVPSTFSWL	ITIH3	731	Q06033
TISPEFWTWAQTLGA	PNMA3	136	Q9UL41
ISAVNPFIWTWNTAF	SLC9A3	356	P48764
WLFWNSPSSPSSSAA	RHOBTB2	701	Q9BYZ6
LNDTWVSFPSWSEDS	SIN3A	581	Q96ST3
LNDTWVSFPSWSEDS	SIN3B	456	O75182
PQSTFTPWASWVSRV	SPATA31E1	871	Q6ZUB1
VAWTTTPWTLPSNLA	IARS1	221	P41252
LSWTWGSLTLSPSQS	SIGLEC12	411	Q96PQ1
DWSRPSWSLVLTISF	STRC	1756	Q7RTU9
SSLSPSQFLQFKTWW	ERVK-9	356	P63128
AKSAWSSVFSPWIQG	ACSM3	281	Q53FZ2
SATPTSTQWAWDSGQ	CEP164	1326	Q9UPV0
PWLWEDGSTFSSNLF	CLEC7A	191	Q9BXN2
LSSSPWSAQPTWKSD	INPP5J	406	Q15735
FVLWLPSSSPSWVST	TMEM86A	26	Q8N2M4
WTFTVLGSSTWSPVQ	TAS1R1	461	Q7RTX1
LSWVVAQSSPEAWSF	PRR19	336	A6NJB7
WSALARSWLTASSAS	SPANXA2-OT1	111	Q8N9U9
SLSTNDFSIPWETWQ	SYCP2	1336	Q9BX26
SGLWSTTPFSSSIWS	TMEM131	1796	Q92545
VSWWANSSLEPADLS	SERPINE3	131	A8MV23
FLKAWPWQNSTITFV	TTTY12	11	Q9BZ98
VSLWSRLSSSWESLQ	SPTB	2116	P11277
SPWIAWLETNGATST	TGM5	86	O43548
SKSFWESPNTNWTLL	TTLL6	701	Q8N841
QPTWTTFSYTVWLGS	PRSS48	71	Q7RTY5
SPNWLSRTYSSHVSW	ZSWIM8	1296	A7E2V4
QLPSDWEAFDTSLWS	TEX13A	331	Q9BXU3
TSASTHAWSRPLWYQ	TMEM89	16	A2RUT3
PLSTSNQWLWVSDDT	USP30	466	Q70CQ3
SANCGLPSSWTSTWQ	TASOR2	1951	Q5VWN6
LPSSWTSTWQVADDL	TASOR2	1956	Q5VWN6
SVDSLLFVLSSPHWW	TPTE2P1	76	Q5T6R2
SNSTSAPNWKSLTSW	ZC3HAV1	351	Q7Z2W4
VKRSQSSWSLPSHWS	USP31	676	Q70CQ4
NTASASSWPVFSSAW	TRIM4	331	Q9C037
VPGVSTLFSWSSLSW	XKR5	141	Q6UX68
NPSWWLLNTSALITA	VN1R3	261	Q9BXE9
SFQSELPWKNCSSWS	SLC6A14	146	Q9UN76
TAWQSLTQVLTPESW	ZNF285	136	Q96NJ3