Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A FAM13B TBC1D3C TBC1D3B TBC1D9 RASGRP3 TBC1D3I ARHGAP8 TBC1D3G TBC1D3K TBC1D3F

1.70e-1127912316GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D3E PSD2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A ECT2L FAM13B TBC1D3C TBC1D3B TBC1D9 RASGRP1 RASGRP3 TBC1D3I ARHGAP8 TBC1D3G VAV2 TBC1D3K TBC1D3F

3.83e-1150712320GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D3E PSD2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A ECT2L FAM13B TBC1D3C TBC1D3B TBC1D9 RASGRP1 RASGRP3 TBC1D3I ARHGAP8 TBC1D3G VAV2 TBC1D3K TBC1D3F

3.83e-1150712320GO:0030695
GeneOntologyMolecularFunctionenzyme activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A FAM13B TBC1D3C TBC1D3B TBC1D9 RASGRP3 TBC1D3I ARHGAP8 TBC1D3G TBC1D3K TBC1D3F

2.78e-0665612316GO:0008047
GeneOntologyMolecularFunctionenzyme regulator activity

TBC1D3E PSD2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A CCNP ECT2L ADGRV1 FAM13B TBC1D3C TBC1D3B TBC1D9 RASGRP1 IBTK RASGRP3 AKT1 TBC1D3I ARHGAP8 TBC1D3G VAV2 TBC1D3K TBC1D3F

5.04e-06141812324GO:0030234
GeneOntologyMolecularFunctionphosphotyrosine residue binding

CRK CRKL PLCG2 VAV2

2.74e-04511234GO:0001784
GeneOntologyMolecularFunctiondinitrosyl-iron complex binding

GSTA1 GSTA2

3.72e-0451232GO:0035731
GeneOntologyMolecularFunctionprotein serine kinase activity

TRPM6 STK31 TTK PRKACA PRKACB RPS6KA6 AKT1 PRKDC ULK2

4.19e-043631239GO:0106310
GeneOntologyMolecularFunctionmolecular function activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A FAM13B TBC1D3C TBC1D3B TBC1D9 RASGRP3 PRKACA AKT1 TBC1D3I ARHGAP8 TBC1D3G TBC1D3K TBC1D3F

5.48e-04123312318GO:0140677
GeneOntologyMolecularFunctionpyrophosphatase activity

KIF13B RAB11B KIF6 MTG2 WRN RAB11A ATAD2 ATL1 KIF3A GPN2 MCM9 SMARCA4 ENPP5 GNA15

6.63e-0483912314GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

KIF13B RAB11B KIF6 MTG2 WRN RAB11A ATAD2 ATL1 KIF3A GPN2 MCM9 SMARCA4 ENPP5 GNA15

6.71e-0484012314GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

KIF13B RAB11B KIF6 MTG2 WRN RAB11A ATAD2 ATL1 KIF3A GPN2 MCM9 SMARCA4 ENPP5 GNA15

6.71e-0484012314GO:0016818
GeneOntologyMolecularFunctionsteroid delta-isomerase activity

GSTA1 GSTA2

7.75e-0471232GO:0004769
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKACA PRKACB

7.75e-0471232GO:0004691
GeneOntologyMolecularFunctionprotein phosphorylated amino acid binding

CRK CRKL PLCG2 VAV2

8.70e-04691234GO:0045309
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF13B RAB11B KIF6 MTG2 WRN RAB11A ATAD2 ATL1 KIF3A GPN2 MCM9 SMARCA4 GNA15

9.90e-0477512313GO:0017111
GeneOntologyMolecularFunctioncyclic nucleotide-dependent protein kinase activity

PRKACA PRKACB

1.32e-0391232GO:0004690
GeneOntologyMolecularFunctionhistone H3K14 acetyltransferase activity

KAT6A KAT6B

1.32e-0391232GO:0036408
GeneOntologyMolecularFunctionATP-dependent activity

KIF13B KIF6 MYO9A WRN ATAD2 KIF3A MCM9 SMARCA2 SMARCA4 HELZ ATP6V0A2

1.46e-0361412311GO:0140657
GeneOntologyMolecularFunctionAMP-activated protein kinase activity

PRKACA PRKACB

1.64e-03101232GO:0004679
GeneOntologyMolecularFunctionchannel activator activity

PRKACA AKT1

1.64e-03101232GO:0099103
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TRPM6 STK31 TTK PRKACA PRKACB RPS6KA6 AKT1 PRKDC ULK2

1.78e-034461239GO:0004674
GeneOntologyMolecularFunctionmismatch repair complex binding

WRN MCM9

2.00e-03111232GO:0032404
GeneOntologyMolecularFunction14-3-3 protein binding

KIF13B ARRB2 AKT1

2.20e-03421233GO:0071889
GeneOntologyMolecularFunctionprotein tyrosine kinase binding

DSCAM CRK CRKL PTPN2 PLCG2

2.31e-031491235GO:1990782
GeneOntologyMolecularFunctiontransporter activator activity

PRKACA AKT1

2.39e-03121232GO:0141109
GeneOntologyMolecularFunctionarrestin family protein binding

ARRDC1 ARRB2

2.39e-03121232GO:1990763
GeneOntologyMolecularFunctionhelicase activity

WRN MCM9 SMARCA2 SMARCA4 HELZ

2.97e-031581235GO:0004386
GeneOntologyMolecularFunctionprotein serine/threonine/tyrosine kinase activity

TTK PRKACA AKT1

3.04e-03471233GO:0004712
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D9 CRK CRKL RASGRP1 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.28e-1610912415GO:0090630
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A PLXND1 TBC1D3C TBC1D3B TBC1D9 CRK CRKL RASGRP1 RASGRP3 TBC1D3I TBC1D3G VAV2 TBC1D3K TBC1D3F

1.48e-1333512419GO:0043087
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A TBC1D3C TBC1D3B TBC1D9 CRK CRKL RASGRP1 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.57e-1224412416GO:0043547
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A WRN TBC1D3C TBC1D3B TBC1D9 CRK CRKL RASGRP1 PTPRC AKT1 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.52e-1049912419GO:0051345
GeneOntologyBiologicalProcessregulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A WRN PLXND1 CMYA5 TBC1D3C TBC1D3B TBC1D9 CRK CRKL RASGRP1 PTPRC RASGRP3 AKT1 TBC1D3I TBC1D3G VAV2 TBC1D3K TBC1D3F

2.30e-0987812423GO:0051336
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A WRN TSHR TBC1D3C TBC1D3B TBC1D9 CRK CRKL RASGRP1 IGF1R ARRB2 PTPRC AKT1 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.93e-07102812422GO:0043085
GeneOntologyBiologicalProcesspositive regulation of molecular function

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYO9A WRN TSHR PLXND1 TBC1D3C TBC1D3B TBC1D9 CRK CRKL RASGRP1 IGF1R ARRB2 PTPRC SMARCA4 AKT1 PLCG2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.12e-06143012425GO:0044093
GeneOntologyBiologicalProcesscalcium ion transport

TRPM6 ASIC1 CDH23 IBTK ARRB2 PTPRC PKD2L2 PRKACA AKT1 TRPM1 PLCG2 PLCH1 NALF2

1.22e-0550912413GO:0006816
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

TRPM6 ASIC1 IBTK PTPRC PKD2L2 PRKACA AKT1 TRPM1 PLCG2 PLCH1 NALF2

2.52e-0539212411GO:0070588
GeneOntologyBiologicalProcessneuron projection development

KIF13B DSCAM MYO9A FAT3 RAB11A CDH23 TSHR PLXND1 ADGRV1 ATL1 CRK CRKL KIF3A SLITRK2 IGF1R PBRM1 NFIX AKT1 ULK2 TNXB

8.04e-05128512420GO:0031175
GeneOntologyBiologicalProcesshelper T cell diapedesis

CRK CRKL

1.07e-0431242GO:0035685
GeneOntologyBiologicalProcessneuron development

KIF13B DSCAM MYO9A FAT3 RAB11A CDH23 TSHR PLXND1 ADGRV1 ATL1 CRK CRKL KIF3A SLITRK2 IGF1R PBRM1 NFIX AKT1 TRPM1 ULK2 TNXB

1.63e-04146312421GO:0048666
GeneOntologyBiologicalProcesspositive regulation of DNA metabolic process

WRN IGF1R ARRB2 PBRM1 PTPRC SMARCA2 SMARCA4 AKT1 PRKDC

1.87e-043331249GO:0051054
GeneOntologyBiologicalProcesscerebellar neuron development

CRK CRKL

2.13e-0441242GO:0098749
GeneOntologyBiologicalProcesshelper T cell extravasation

CRK CRKL

2.13e-0441242GO:0035684
MousePhenoenlarged ovary

FAT3 WRN SLITRK2 MCM9 GNA15

2.05e-0551925MP:0004832
MousePhenoaberrant origin of the right subclavian artery

MYO9A KAT6A PLXND1 CRKL

6.21e-0533924MP:0010465
MousePhenohydrocephaly

KIF6 DSCAM MYO9A CFAP43 KIF3A DNAAF5 NFIX VAV2

6.93e-05209928MP:0001891
MousePhenodilated third ventricle

KIF6 DSCAM CFAP43 NFIX

7.00e-0534924MP:0000827
MousePhenoabnormal CD8-positive, naive alpha-beta T cell number

RASGRP1 PTPRC RASGRP3 PRKDC PLCG2

7.75e-0567925MP:0013434
MousePhenoabnormal positive T cell selection

PTPN2 RASGRP1 PTPRC

9.53e-0514923MP:0004919
MousePhenoabnormal aortic arch and aortic arch branch attachment

MYO9A KAT6A PLXND1 CRKL

9.83e-0537924MP:0010464
MousePhenoabnormal right subclavian artery morphology

MYO9A KAT6A PLXND1 CRKL

1.34e-0440924MP:0010487
MousePhenoabnormal third ventricle morphology

KIF6 DSCAM MYO9A CFAP43 NFIX

1.60e-0478925MP:0000826
MousePhenodecreased outer hair cell stereocilia number

CDH23 TSHR ADGRV1

2.10e-0418923MP:0004529
DomainTBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D9 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.26e-144912111SM00164
DomainRabGAP-TBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D9 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

3.22e-145312111PF00566
DomainRab-GTPase-TBC_dom

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D9 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

5.00e-145512111IPR000195
DomainTBC_RABGAP

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D9 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

5.00e-145512111PS50086
DomainHEAT

CKAP5 XPO1 DNAAF5 MMS19 PRKDC

3.66e-05581215IPR000357
DomainGln-Leu-Gln_QLQ

SMARCA2 SMARCA4

4.16e-0521212IPR014978
DomainSnAC

SMARCA2 SMARCA4

4.16e-0521212PF14619
DomainQLQ

SMARCA2 SMARCA4

4.16e-0521212SM00951
DomainQLQ

SMARCA2 SMARCA4

4.16e-0521212PS51666
DomainSnAC

SMARCA2 SMARCA4

4.16e-0521212SM01314
DomainSnAC

SMARCA2 SMARCA4

4.16e-0521212IPR029295
DomainQLQ

SMARCA2 SMARCA4

4.16e-0521212PF08880
DomainHEAT_REPEAT

CKAP5 XPO1 DNAAF5 MMS19 PRKDC

9.08e-05701215PS50077
DomainBROMODOMAIN_1

ATAD2 PBRM1 SMARCA2 SMARCA4

9.38e-05371214PS00633
DomainBromodomain

ATAD2 PBRM1 SMARCA2 SMARCA4

1.04e-04381214PF00439
DomainP-loop_NTPase

KIF13B RAB11B KIF6 MYO9A MTG2 WRN RAB11A ATAD2 ATL1 KIF3A GPN2 MCM9 SMARCA2 SMARCA4 HELZ GNA15

1.17e-0484812116IPR027417
DomainBROMODOMAIN_2

ATAD2 PBRM1 SMARCA2 SMARCA4

1.41e-04411214PS50014
DomainBromodomain

ATAD2 PBRM1 SMARCA2 SMARCA4

1.55e-04421214IPR001487
DomainBROMO

ATAD2 PBRM1 SMARCA2 SMARCA4

1.55e-04421214SM00297
Domain-

ATAD2 PBRM1 SMARCA2 SMARCA4

1.55e-044212141.20.920.10
DomainHSA

SMARCA2 SMARCA4

2.48e-0441212SM00573
DomainTRPM_tetra

TRPM6 TRPM1

2.48e-0441212PF16519
DomainHSA

SMARCA2 SMARCA4

2.48e-0441212PS51204
DomainTRPM_tetra

TRPM6 TRPM1

2.48e-0441212IPR032415
DomainHSA_dom

SMARCA2 SMARCA4

2.48e-0441212IPR014012
DomainHSA

SMARCA2 SMARCA4

2.48e-0441212PF07529
DomainHEAT

CKAP5 DNAAF5 MMS19 PRKDC

2.62e-04481214PF02985
DomainHAT_MYST-type

KAT6A KAT6B

4.11e-0451212IPR002717
DomainGST_alpha

GSTA1 GSTA2

4.11e-0451212IPR003080
DomainMOZ_SAS

KAT6A KAT6B

4.11e-0451212PF01853
DomainMYST_HAT

KAT6A KAT6B

4.11e-0451212PS51726
DomainAGC-kinase_C

PRKACA PRKACB RPS6KA6 AKT1

4.75e-04561214IPR000961
DomainAGC_KINASE_CTER

PRKACA PRKACB RPS6KA6 AKT1

4.75e-04561214PS51285
DomainS_TK_X

PRKACA PRKACB RPS6KA6 AKT1

4.75e-04561214SM00133
DomainBRK

SMARCA2 SMARCA4

6.14e-0461212SM00592
DomainBRK_domain

SMARCA2 SMARCA4

6.14e-0461212IPR006576
DomainBRK

SMARCA2 SMARCA4

6.14e-0461212PF07533
DomainBromodomain_CS

PBRM1 SMARCA2 SMARCA4

6.18e-04261213IPR018359
DomainZF_DAG_PE_1

MYO9A RASGRP1 RASGRP3 VAV2

7.89e-04641214PS00479
DomainZF_DAG_PE_2

MYO9A RASGRP1 RASGRP3 VAV2

7.89e-04641214PS50081
DomainC1

MYO9A RASGRP1 RASGRP3 VAV2

8.37e-04651214SM00109
DomainPE/DAG-bd

MYO9A RASGRP1 RASGRP3 VAV2

8.86e-04661214IPR002219
DomainC2

UNC13D PLA2G4B RAB11FIP5 PLCG2 PLCH1

1.63e-031311215PF00168
DomainArrestin-like_N

ARRDC1 ARRB2

1.81e-03101212IPR011021
DomainArrestin_C-like

ARRDC1 ARRB2

1.81e-03101212IPR011022
DomainArrestin_C

ARRDC1 ARRB2

1.81e-03101212SM01017
DomainArrestin_C

ARRDC1 ARRB2

1.81e-03101212PF02752
DomainArrestin_N

ARRDC1 ARRB2

1.81e-03101212PF00339
DomainC2

UNC13D PLA2G4B RAB11FIP5 PLCG2 PLCH1

1.99e-031371215SM00239
DomainC2

UNC13D PLA2G4B RAB11FIP5 PLCG2 PLCH1

2.32e-031421215PS50004
DomainKinesin_motor_CS

KIF13B KIF6 KIF3A

2.36e-03411213IPR019821
DomainPkinase_C

PRKACA RPS6KA6 AKT1

2.53e-03421213PF00433
DomainRho_GTPase_activation_prot

MYO9A PLXND1 FAM13B ARHGAP8

2.57e-03881214IPR008936
DomainEF-hand-dom_pair

CFAP251 TBC1D9 RASGRP1 RASGRP3 USP32 PLCG2 PLCH1

2.68e-032871217IPR011992
DomainKinesin-like_fam

KIF13B KIF6 KIF3A

2.71e-03431213IPR027640
DomainKinase-like_dom

TRPM6 STK31 TTK IGF1R PRKACA PRKACB RPS6KA6 AKT1 PRKDC ULK2

2.77e-0354212110IPR011009
Domain-

UNC13D PLA2G4B RAB11FIP5 PLCG2 PLCH1

2.78e-0314812152.60.40.150
Domain-

KIF13B KIF6 KIF3A

2.89e-034412133.40.850.10
DomainKinesin

KIF13B KIF6 KIF3A

2.89e-03441213PF00225
DomainKISc

KIF13B KIF6 KIF3A

2.89e-03441213SM00129
DomainKINESIN_MOTOR_1

KIF13B KIF6 KIF3A

2.89e-03441213PS00411
DomainKinesin_motor_dom

KIF13B KIF6 KIF3A

2.89e-03441213IPR001752
DomainKINESIN_MOTOR_2

KIF13B KIF6 KIF3A

2.89e-03441213PS50067
DomainH15

KAT6A KAT6B

3.10e-03131212SM00526
DomainH15

KAT6A KAT6B

3.10e-03131212PS51504
Domain-

CKAP5 XPO1 ATAD2 DNAAF5 MMS19 PRKDC

3.26e-0322212161.25.10.10
Domain-

RAB11B MTG2 WRN RAB11A ATAD2 ATL1 GPN2 MCM9 SMARCA2 SMARCA4 HELZ GNA15

3.31e-03746121123.40.50.300
DomainHistone_H1/H5_H15

KAT6A KAT6B

3.60e-03141212IPR005818
Domainfn3

DSCAM CMYA5 IGF1R PTPRC TNXB

4.09e-031621215PF00041
DomainTPR-like_helical_dom

CNOT10 TTC14 TTK HELZ TTC13 PRKDC

4.13e-032331216IPR011990
DomainEF-hand_like

PLCG2 PLCH1

4.14e-03151212PF09279
DomainPI-PLC-Y

PLCG2 PLCH1

4.14e-03151212PF00387
DomainPLCYc

PLCG2 PLCH1

4.14e-03151212SM00149
DomainPLipase_C_Pinositol-sp_Y

PLCG2 PLCH1

4.14e-03151212IPR001711
DomainPIPLC_Y_DOMAIN

PLCG2 PLCH1

4.14e-03151212PS50008
DomainPI-PLC_fam

PLCG2 PLCH1

4.14e-03151212IPR001192
DomainPLC_EF-hand-like

PLCG2 PLCH1

4.14e-03151212IPR015359
DomainSH2

CRK CRKL PLCG2 VAV2

4.22e-031011214PF00017
DomainC2_dom

UNC13D PLA2G4B RAB11FIP5 PLCG2 PLCH1

4.31e-031641215IPR000008
DomainHEAT_type_2

CKAP5 DNAAF5

5.31e-03171212IPR021133
DomainSH2

CRK CRKL PLCG2 VAV2

5.71e-031101214SM00252
DomainSH2

CRK CRKL PLCG2 VAV2

5.89e-031111214PS50001
DomainPI-PLC-X

PLCG2 PLCH1

5.95e-03181212PF00388
DomainPLCXc

PLCG2 PLCH1

5.95e-03181212SM00148
DomainC1_1

RASGRP1 RASGRP3 VAV2

6.02e-03571213PF00130
DomainSH2

CRK CRKL PLCG2 VAV2

6.08e-031121214IPR000980
Domain-

CRK CRKL PLCG2 VAV2

6.08e-0311212143.30.505.10
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K

1.40e-0899919M46448
PathwayKEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS

CRK CRKL PTPRC PLA2G4B AKT1 PLCG2 VAV2

2.76e-0696917M16121
PathwayWP_B_CELL_RECEPTOR_SIGNALING

CRK CRKL PTPRC RASGRP3 AKT1 PLCG2 VAV2

2.96e-0697917M39323
PathwayKEGG_MAPK_SIGNALING_PATHWAY

CRK CRKL RASGRP1 ARRB2 PLA2G4B RASGRP3 PRKACA PRKACB RPS6KA6 AKT1

8.37e-062679110M10792
PathwayPID_HEDGEHOG_GLI_PATHWAY

XPO1 KIF3A ARRB2 PRKACA AKT1

1.38e-0548915M219
PathwayWP_RAS_SIGNALING

RASGRP1 IGF1R PLA2G4B RASGRP3 PRKACA PRKACB AKT1 PLCG2

2.44e-05184918M39764
PathwayWP_MAPK_SIGNALING

CRK CRKL RASGRP1 ARRB2 PLA2G4B RASGRP3 PRKACA PRKACB AKT1

2.93e-05246919M39597
PathwayPID_TXA2PATHWAY

RAB11A ARRB2 PRKACA AKT1 GNA15

2.96e-0556915M99
PathwayPID_IGF1_PATHWAY

CRK CRKL IGF1R AKT1

3.41e-0529914M125
PathwayWP_GPR143_IN_MELANOCYTES_AND_RETINAL_PIGMENT_EPITHELIUM_CELLS

ARRB2 PRKACA PRKACB GNA15

3.92e-0530914M42578
PathwayKEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY

CRK CRKL AKT1

4.14e-0511913M47406
PathwayPID_BCR_5PATHWAY

IBTK PTPRC AKT1 PLCG2 VAV2

5.25e-0563915M10
PathwayPID_IL8_CXCR2_PATHWAY

RAB11A ARRB2 AKT1 GNA15

6.50e-0534914M210
PathwayPID_ARF6_PATHWAY

KIF13B TSHR ARRB2 GNA15

7.30e-0535914M86
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

PRKACA PRKACB SMARCA2 SMARCA4

7.30e-0535914M47969
PathwayREACTOME_RAP1_SIGNALLING

RASGRP1 PRKACA PRKACB

1.12e-0415913MM15019
PathwayREACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS

PRKACA PRKACB RPS6KA6

1.12e-0415913MM15103
PathwayREACTOME_RAP1_SIGNALLING

RASGRP1 PRKACA PRKACB

1.37e-0416913M923
PathwayWP_HEDGEHOG_SIGNALING_WP4249

KIF3A ARRB2 PRKACA PRKACB

1.65e-0443914M39706
PathwayWP_VASOPRESSINREGULATED_WATER_REABSORPTION

RAB11B RAB11A PRKACA PRKACB

1.81e-0444914M42554
PathwayKEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION

RAB11B RAB11A PRKACA PRKACB

1.81e-0444914M9011
PathwayWP_CHEMOKINE_SIGNALING_PATHWAY

CRK CRKL ARRB2 PRKACA PRKACB AKT1 VAV2

1.85e-04184917MM15943
PathwayKEGG_CHEMOKINE_SIGNALING_PATHWAY

CRK CRKL ARRB2 PRKACA PRKACB AKT1 VAV2

2.11e-04188917M4844
PathwayKEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION

IGF1R PRKACA PRKACB RPS6KA6 AKT1

2.19e-0485915M3578
PathwayWP_RETT_SYNDROME

CRK SYNE2 SMARCA2 SMARCA4

2.54e-0448914M39759
PathwayREACTOME_HEMOSTASIS

KIF13B KIF6 CRK KIF3A RASGRP1 ARRB2 PRKACA PRKACB AKT1 GNA15 PLCG2 VAV2

2.95e-045719112MM14472
PathwayWP_FOCAL_ADHESION

CHAD CRK CRKL IGF1R AKT1 TNXB VAV2

2.99e-04199917M39402
PathwayKEGG_FOCAL_ADHESION

CHAD CRK CRKL IGF1R AKT1 TNXB VAV2

2.99e-04199917M7253
PathwayBIOCARTA_IGF1R_PATHWAY

IGF1R PRKACB AKT1

3.67e-0422913MM1438
PathwayKEGG_VIBRIO_CHOLERAE_INFECTION

PRKACA PRKACB PLCG2 ATP6V0A2

4.02e-0454914M17906
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS

PRKACA PRKACB

4.07e-045912M26988
PathwayREACTOME_ACTIVATION_OF_RAS_IN_B_CELLS

RASGRP1 RASGRP3

4.07e-045912M26921
PathwayWP_CANCER_PATHWAYS

CRK CRKL GSTA1 GSTA2 RASGRP1 IGF1R RASGRP3 PRKACA PRKACB AKT1 PLCG2

4.10e-045079111M48302
PathwayBIOCARTA_IGF1R_PATHWAY

IGF1R PRKACB AKT1

4.20e-0423913M19613
PathwayREACTOME_AZATHIOPRINE_ADME

GSTA1 GSTA2 VAV2

4.20e-0423913M45013
PathwayBIOCARTA_BAD_PATHWAY

IGF1R PRKACB AKT1

4.77e-0424913MM1467
PathwayREACTOME_SIGNALING_BY_VEGF

CRK PRKACA PRKACB AKT1 VAV2

5.34e-04103915MM14752
PathwayBIOCARTA_BAD_PATHWAY

IGF1R PRKACB AKT1

5.40e-0425913M85
PathwayWP_MAPK_SIGNALING_PATHWAY

CRK CRKL RASGRP1 ARRB2 PRKACA AKT1

5.86e-04160916MM15990
PathwayWP_SOMATROPH_AXIS_GH_AND_ITS_RELATIONSHIP_TO_DIETARY_RESTRICTION_AND_AGING

IGF1R AKT1

6.08e-046912M39742
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

PRKACA PRKACB

6.08e-046912MM14628
PathwayREACTOME_SIGNALING_BY_VEGF

CRK PRKACA PRKACB AKT1 VAV2

6.09e-04106915M27077
PathwayWP_THERMOGENESIS

PRKACA PRKACB RPS6KA6 SMARCA2 SMARCA4

6.63e-04108915M39746
PathwayREACTOME_AZATHIOPRINE_ADME

GSTA1 GSTA2 VAV2

6.80e-0427913MM15693
PathwayREACTOME_INTEGRIN_SIGNALING

CRK RASGRP1 AKT1

6.80e-0427913M760
PathwayWP_CHEMOKINE_SIGNALING

CRK CRKL ARRB2 PRKACB AKT1 VAV2

6.89e-04165916M39400
PathwayWP_ANDROGEN_RECEPTOR_NETWORK_IN_PROSTATE_CANCER

CRK CRKL SMARCA4 AKT1 PRKDC

7.21e-04110915M48043
PathwayWP_ENDOCHONDRAL_OSSIFICATION

KIF3A IGF1R PRKACA AKT1

7.24e-0463914M39646
PathwayWP_ENDOCHONDRAL_OSSIFICATION_WITH_SKELETAL_DYSPLASIAS

KIF3A IGF1R PRKACA AKT1

7.24e-0463914M39884
PathwayPID_IL8_CXCR1_PATHWAY

ARRB2 AKT1 GNA15

7.58e-0428913M252
PathwayREACTOME_INTEGRIN_SIGNALING

CRK RASGRP1 AKT1

7.58e-0428913MM14958
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

KAT6A SMARCA2 AKT1 PRKDC

8.15e-0465914M39682
PathwayWP_LIPID_METABOLISM_PATHWAY

PRKACA PRKACB AKT1

8.42e-0429913M39762
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

TSHR PRKACA PRKACB

8.42e-0429913M47627
PathwayKEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME

PRKACA PRKACB

8.47e-047912M47896
PathwayREACTOME_HDL_ASSEMBLY

PRKACA PRKACB

8.47e-047912MM15560
PathwayWP_ENDOCHONDRAL_OSSIFICATION

KIF3A IGF1R PRKACA AKT1

8.63e-0466914MM15875
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

KIF13B KIF6 KIF3A PRKACA PRKACB

9.16e-04116915MM15715
PathwayPID_AURORA_A_PATHWAY

CKAP5 PRKACA AKT1

1.03e-0331913M242
PathwayREACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS

RAB11A PRKACA PRKACB

1.03e-0331913MM15094
PathwayKEGG_ENDOCYTOSIS

RAB11B PSD2 RAB11A IGF1R ARRB2 RAB11FIP5

1.11e-03181916M1519
PathwayREACTOME_HDL_ASSEMBLY

PRKACA PRKACB

1.13e-038912M27840
PathwayWP_KIT_RECEPTOR_SIGNALING_PATHWAY

CRK CRKL AKT1 VAV2

1.14e-0371914MM15947
PathwayPID_EPO_PATHWAY

CRKL PLCG2 VAV2

1.23e-0333913M233
PathwayPID_INTEGRIN_A4B1_PATHWAY

CRK PRKACA PRKACB

1.23e-0333913M277
PathwayKEGG_NEUROTROPHIN_SIGNALING_PATHWAY

CRK CRKL RPS6KA6 AKT1 PLCG2

1.33e-03126915M16763
PathwayPID_EPHA_FWDPATHWAY

CRK CRKL VAV2

1.35e-0334913M177
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

CRK RASGRP1 ARRB2 AKT1 GNA15 PLCG2 VAV2

1.36e-03257917MM15454
PathwayREACTOME_HEMOSTASIS

KIF13B KIF6 CRK KIF3A RASGRP1 ARRB2 PRKACA PRKACB AKT1 GNA15 PLCG2 VAV2

1.36e-036799112M8395
PathwayKEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY

RASGRP3 AKT1 PLCG2 VAV2

1.39e-0375914M5436
PathwayREACTOME_ROBO_RECEPTORS_BIND_AKAP5

PRKACA PRKACB

1.44e-039912M27877
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

XPO1 AKT1

1.44e-039912MM15666
PathwayPID_PI3KCI_AKT_PATHWAY

PRKACA AKT1 PRKDC

1.47e-0335913M249
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

PRKACA PRKACB RPS6KA6

1.47e-0335913MM15109
PathwayREACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

CRK RASGRP1 ARRB2 AKT1 GNA15 PLCG2 VAV2

1.48e-03261917M1077
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

CRK CRKL PTPN2 IGF1R PRKACA PRKACB AKT1 VAV2 ATP6V0A2

1.49e-03418919MM15587
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

PTPRC AKT1 PLCG2

1.59e-0336913M1315
PathwayPID_MET_PATHWAY

CRK CRKL PTPN2 AKT1

1.69e-0379914M48
PathwayKEGG_FC_EPSILON_RI_SIGNALING_PATHWAY

PLA2G4B AKT1 PLCG2 VAV2

1.69e-0379914M11816
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

PBRM1 SMARCA2 SMARCA4

1.73e-0337913M27797
PathwayREACTOME_MET_RECEPTOR_RECYCLING

CRK CRKL

1.79e-0310912M27777
PathwayKEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY

PRKACA PRKACB

1.79e-0310912M47648
PathwayREACTOME_MET_RECEPTOR_RECYCLING

CRK CRKL

1.79e-0310912MM15516
PathwayWP_NONHOMOLOGOUS_END_JOINING

WRN PRKDC

1.79e-0310912M39469
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

CRK RASGRP1 AKT1

1.86e-0338913MM15456
PathwayKEGG_INSULIN_SIGNALING_PATHWAY

CRK CRKL PRKACA PRKACB AKT1

1.92e-03137915M18155
PathwayPID_REG_GR_PATHWAY

PRKACA PRKACB SMARCA4 AKT1

1.94e-0382914M115
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

CRK RASGRP1 AKT1

2.01e-0339913M10735
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

PRKACA PRKACB GNA15

2.01e-0339913MM14496
PathwayPID_ECADHERIN_NASCENT_AJ_PATHWAY

CRK AKT1 VAV2

2.01e-0339913M156
PathwayPID_ER_NONGENOMIC_PATHWAY

IGF1R AKT1 GNA15

2.16e-0340913M41
PathwayREACTOME_AQUAPORIN_MEDIATED_TRANSPORT

RAB11A PRKACA PRKACB

2.16e-0340913MM15115
PathwayPID_IFNG_PATHWAY

CRKL PTPN2 AKT1

2.16e-0340913M161
PathwayREACTOME_MET_ACTIVATES_RAP1_AND_RAC1

CRK CRKL

2.18e-0311912M27776
PathwayREACTOME_MET_ACTIVATES_RAP1_AND_RAC1

CRK CRKL

2.18e-0311912MM15515
PathwayKEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY

IGF1R AKT1

2.18e-0311912M47484
PathwayREACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING

CRK CRKL PRKACA

2.32e-0341913MM15162
PathwayKEGG_ERBB_SIGNALING_PATHWAY

CRK CRKL AKT1 PLCG2

2.40e-0387914M12467
PathwayREACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM

PRKACA PRKACB

2.61e-0312912M27950
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE

PRKACA PRKACB

2.61e-0312912M27363
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

7.51e-28111241116863688
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

TRPM6 KAT6A PLXND1 CRK CRKL KIF3A IGF1R PLA2G4B PRKACA PRKACB RPS6KA6 SMARCA2 SMARCA4 ADAM33 AKT1 KAT6B ULK2 ATP6V0A2

1.31e-107301241834857952
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C USP32

7.67e-105124412604796
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F

9.11e-0974124716625196
Pubmed

Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.

WRN SMARCA2 SMARCA4 PRKDC

7.45e-0812124415140983
Pubmed

Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis.

RAB11B RAB11A RAB11FIP5

1.76e-074124319335615
Pubmed

FIP5 phosphorylation during mitosis regulates apical trafficking and lumenogenesis.

RAB11A KIF3A RAB11FIP5

1.76e-074124324591568
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3 TBC1D3D TBC1D3F

1.76e-074124312359748
Pubmed

Mutational analysis of the interaction between insulin receptor and IGF-I receptor with c-Crk and Crk-L in a yeast two-hybrid system.

CRK CRKL IGF1R

1.76e-074124315522217
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3 TBC1D3D TBC1D3F

1.76e-07412438406013
Pubmed

Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes.

KIF3A IGF1R AKT1

4.40e-075124319596798
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3 TBC1D3D TBC1D3F

4.40e-07512438471161
Pubmed

Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways.

PRKACA PRKACB AKT1

4.40e-075124319483721
Pubmed

Structural and functional analysis of FIP2 binding to the endosome-localised Rab25 GTPase.

RAB11B RAB11A RAB11FIP5

4.40e-075124324056041
Pubmed

Proapoptotic function of the nuclear Crk II adaptor protein.

XPO1 CRK CRKL

8.78e-076124317764157
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

UBR2 MYO9A VPS13C KIAA0232 KAT6A TTC14 ADGRV1 DNAAF5 AP1S1 IGF1R ARRB2 NFIX PRKACB SMARCA2 ENPP5 ZFHX3 KAT6B ARHGAP8 VAV2

1.41e-0614891241928611215
Pubmed

Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors.

CRK CRKL VAV2

1.53e-06712438621483
Pubmed

Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis.

RAB11B RAB11A AKT1

1.53e-067124331204173
Pubmed

Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins.

RAB11B RAB11A RAB11FIP5

1.53e-067124311481332
Pubmed

Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1.

CRK CRKL PLCG2 VAV2

1.55e-0624124420624904
Pubmed

Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation.

CRK CRKL AKT1

3.66e-069124316982329
Pubmed

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

IGF1R PBRM1 SMARCA4 AKT1 PRKDC

5.73e-0671124528319113
Pubmed

Identification and characterization of a family of Rab11-interacting proteins.

RAB11B RAB11A RAB11FIP5

7.15e-0611124311495908
Pubmed

MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.

GSTA1 GSTA2 GNA15

9.51e-061212438297798
Pubmed

A human MAP kinase interactome.

MYO9A CFAP36 KIAA0232 FAM13B KIF3A ARRB2 PRKACA HELZ PRKDC TBC1D3F

1.02e-054861241020936779
Pubmed

Viral genetic determinants of nonprogressive HIV type 1 subtype C infection in antiretroviral drug-naive children.

AP1S1 PRKACA PRKACB

1.23e-0513124319895210
Pubmed

Crk and CrkL present with different expression and significance in epithelial ovarian carcinoma.

CRK CRKL

1.26e-052124221319228
Pubmed

PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival.

AKT1 PRKDC

1.26e-052124218439899
Pubmed

Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway.

CRK CRKL

1.26e-052124219074029
Pubmed

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

SMARCA2 SMARCA4

1.26e-05212428670841
Pubmed

Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.

CRK CRKL

1.26e-052124222569336
Pubmed

Importance of the REM (Ras exchange) domain for membrane interactions by RasGRP3.

RASGRP1 RASGRP3

1.26e-052124228912101
Pubmed

Polymorphism of human Alpha class glutathione transferases.

GSTA1 GSTA2

1.26e-052124211668220
Pubmed

Physiological signals and oncogenesis mediated through Crk family adapter proteins.

CRK CRKL

1.26e-052124210092207
Pubmed

Luteolin inhibits insulin-like growth factor 1 receptor signaling in prostate cancer cells.

IGF1R AKT1

1.26e-052124217065200
Pubmed

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.

SMARCA2 SMARCA4

1.26e-052124223163725
Pubmed

Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA.

GSTA1 GSTA2

1.26e-05212423800996
Pubmed

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB

1.26e-05212423023318
Pubmed

Protein kinase B/AKT 1 plays a pivotal role in insulin-like growth factor-1 receptor signaling induced 3T3-L1 adipocyte differentiation.

IGF1R AKT1

1.26e-052124215192111
Pubmed

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.

SMARCA2 SMARCA4

1.26e-052124223076393
Pubmed

Nucleotide sequence of the human liver glutathione S-transferase subunit 1 cDNA.

GSTA1 GSTA2

1.26e-05212423678589
Pubmed

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

SMARCA2 SMARCA4

1.26e-052124215576411
Pubmed

Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis.

CRK CRKL

1.26e-052124224499776
Pubmed

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

SMARCA2 SMARCA4

1.26e-052124215240517
Pubmed

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.

SMARCA2 SMARCA4

1.26e-052124226564006
Pubmed

SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.

SMARCA2 SMARCA4

1.26e-052124233027072
Pubmed

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

SMARCA2 SMARCA4

1.26e-052124223872584
Pubmed

The basic glutathione S-transferases from human livers are products of separate genes.

GSTA1 GSTA2

1.26e-05212423036131
Pubmed

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

SMARCA2 SMARCA4

1.26e-052124223088494
Pubmed

Munc13-4 Is a Rab11-binding Protein That Regulates Rab11-positive Vesicle Trafficking and Docking at the Plasma Membrane.

RAB11A UNC13D

1.26e-052124226637356
Pubmed

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.

SMARCA2 SMARCA4

1.26e-052124220333683
Pubmed

SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.

SMARCA2 SMARCA4

1.26e-052124234812766
Pubmed

The extended catalysis of glutathione transferase.

GSTA1 GSTA2

1.26e-052124221163259
Pubmed

TSHR-IGF-IR complex drives orbital fibroblast misbehavior in thyroid eye disease.

TSHR IGF1R

1.26e-052124239082947
Pubmed

Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.

GSTA1 GSTA2

1.26e-052124215128049
Pubmed

Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.

SMARCA2 SMARCA4

1.26e-052124230478150
Pubmed

Tyrosine phosphorylation of murine Crkl.

CRK CRKL

1.26e-05212427478571
Pubmed

Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression.

GSTA1 GSTA2

1.26e-052124211692074
Pubmed

Evidence for an association between thyroid-stimulating hormone and insulin-like growth factor 1 receptors: a tale of two antigens implicated in Graves' disease.

TSHR IGF1R

1.26e-052124218768899
Pubmed

Fibroblast Growth Requires CT10 Regulator of Kinase (Crk) and Crk-like (CrkL).

CRK CRKL

1.26e-052124227807028
Pubmed

DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair.

AKT1 PRKDC

1.26e-052124233404607
Pubmed

CRKL but not CRKII contributes to hemin-induced erythroid differentiation of CML.

CRK CRKL

1.26e-052124238683131
Pubmed

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

SMARCA2 SMARCA4

1.26e-052124225808524
Pubmed

Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems.

PRKACA PRKACB

1.26e-052124236152045
Pubmed

PRKACA/PRKACB Fusions in Pancreatobiliary Intraductal Oncocytic Papillary Neoplasms Including Those With Atypical Morphology: An Analysis of 22 Cases Expanding Morphologic Spectrum.

PRKACA PRKACB

1.26e-052124238841868
Pubmed

rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain.

AKT1 PLCG2

1.26e-052124218728011
Pubmed

Disrupted TSH Receptor Expression in Female Mouse Lung Fibroblasts Alters Subcellular IGF-1 Receptor Distribution.

TSHR IGF1R

1.26e-052124226389690
Pubmed

DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif.

AKT1 PRKDC

1.26e-052124219144640
Pubmed

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

SMARCA2 SMARCA4

1.26e-052124219144648
Pubmed

Quantitative assessment of glioblastoma phenotypes in vitro establishes cell migration as a robust readout of Crk and CrkL activity.

CRK CRKL

1.26e-052124233561443
Pubmed

A role for Rab11 in the homeostasis of the endosome-lysosomal pathway.

RAB11B RAB11A

1.26e-052124230981667
Pubmed

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.

SMARCA2 SMARCA4

1.26e-052124229391527
Pubmed

Crk and CrkL are required for cell transformation by v-fos and v-ras.

CRK CRKL

1.26e-052124225557916
Pubmed

ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.

KAT6A KAT6B

1.26e-052124239505971
Pubmed

Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.

SMARCA2 SMARCA4

1.26e-052124237634210
Pubmed

Molecular and behavioral effects of a null mutation in all PKA C beta isoforms.

PRKACA PRKACB

1.26e-052124212139926
Pubmed

Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase.

AKT1 PRKDC

1.26e-052124215262962
Pubmed

Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

SMARCA2 SMARCA4

1.26e-05212428208605
Pubmed

Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling.

CRK CRKL

1.26e-052124218165234
Pubmed

Evidence that glutathione S-transferases B1B1 and B2B2 are the products of separate genes and that their expression in human liver is subject to inter-individual variation. Molecular relationships between the B1 and B2 subunits and other Alpha class glutathione S-transferases.

GSTA1 GSTA2

1.26e-05212422604726
Pubmed

Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.

PRKACA PRKACB

1.26e-05212422833513
Pubmed

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.

SMARCA2 SMARCA4

1.26e-052124211163203
Pubmed

A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes.

RAB11A RAB11FIP5

1.26e-052124211163216
Pubmed

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

SMARCA2 SMARCA4

1.26e-052124212620226
Pubmed

The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase.

IGF1R AKT1

1.26e-052124216478996
Pubmed

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

SMARCA2 SMARCA4

1.26e-052124227039070
Pubmed

Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.

SMARCA2 SMARCA4

1.26e-052124229848589
Pubmed

The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.

KAT6A KAT6B

1.26e-052124224150941
Pubmed

The human thyrotropin receptor is predominantly internalized by beta-arrestin 2.

TSHR ARRB2

1.26e-052124216513835
Pubmed

DNA-PK mediates AKT activation and apoptosis inhibition in clinically acquired platinum resistance.

AKT1 PRKDC

1.26e-052124222131882
Pubmed

Isolation of a cDNA clone and localization of human glutathione S-transferase 2 genes to chromosome band 6p12.

GSTA1 GSTA2

1.26e-05212423031680
Pubmed

Phosphorylation enhances mitochondrial targeting of GSTA4-4 through increased affinity for binding to cytoplasmic Hsp70.

GSTA1 PRKACA

1.26e-052124212646569
Pubmed

β-Arrestin 2 Promotes Hepatocyte Apoptosis by Inhibiting Akt Protein.

ARRB2 AKT1

1.26e-052124226582201
Pubmed

Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease.

CRK CRKL

1.26e-052124222251701
Pubmed

Global consequences of activation loop phosphorylation on protein kinase A.

PRKACA PRKACB

1.26e-052124219965870
Pubmed

Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.

SMARCA2 SMARCA4

1.26e-05212429603422
Pubmed

SWI/SNF gene variants and glioma risk and outcome.

SMARCA2 SMARCA4

1.26e-052124223276717
Pubmed

Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.

SMARCA2 SMARCA4

1.26e-052124227097303
Pubmed

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

SMARCA2 SMARCA4

1.26e-052124228038711
Pubmed

Requirement for Crk and CrkL during postnatal lens development.

CRK CRKL

1.26e-052124232736680
InteractionSNX16 interactions

KIF6 XPO1 ZNF778 RABGGTB

1.93e-06161184int:SNX16
InteractionPMS2 interactions

PSD2 XPO1 SMARCA4 AKT1 MMS19 PRKDC

7.48e-06801186int:PMS2
InteractionCIITA interactions

XPO1 PRKACA SMARCA2 SMARCA4 MMS19

1.74e-05551185int:CIITA
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

3.57e-1314912411chr17q12
Cytoband17q12

TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F

7.74e-0699124517q12
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLA2G4B PLCG2 PLCH1

7.40e-0519793832
GeneFamilyTransient receptor potential cation channels

TRPM6 PKD2L2 TRPM1

2.43e-0428793249
GeneFamilyFibronectin type III domain containing

DSCAM CMYA5 IGF1R PTPRC TNXB

6.78e-04160795555
GeneFamilyPhospholipases

PLA2G4B PLCG2 PLCH1

8.15e-0442793467
GeneFamilySH2 domain containing

CRK CRKL PLCG2 VAV2

1.00e-03101794741
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF13B KIF6 KIF3A

1.06e-0346793622
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

KAT6A KAT6B

2.17e-031679266
GeneFamilyCadherin related

FAT3 CDH23

2.46e-031779224
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

KAT6A KAT6B

2.46e-0317792486
GeneFamilyEF-hand domain containing

TBC1D9 RASGRP1 RASGRP3 USP32 PLCH1

2.71e-03219795863
GeneFamilyGlutathione S-transferases

GSTA1 GSTA2

5.30e-0325792567
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM5 ADAM33

6.16e-032779247
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

MYO9A CFAP36 VPS13C WRN XPO1 ATAD2 TTK FAM13B TBC1D9 ATL1 KIF3A PBRM1 SACS SYNE2 SMARCA2 TRPM1

6.20e-0865612116M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

UBR2 KAT6A WRN CKAP5 XPO1 TTK PTPN2 IBTK IGF1R SACS SYNE2 PRKACB SMARCA2 HELZ ZFHX3 KAT6B

2.12e-0685612116M4500
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

UBR2 KAT6A WRN CKAP5 XPO1 PTPN2 IBTK PRKACB SMARCA2 HELZ KAT6B

1.10e-0546612111M13522
CoexpressionACEVEDO_METHYLATED_IN_LIVER_CANCER_DN

NRAP ASIC1 MYO9A VPS13C KAT6A CPA1 ADGRV1 TBC1D3B IGF1R PKD2L2 ADAM5 MCM9 TBC1D3I TBC1D3G TBC1D3F

1.24e-0587312115M16009
CoexpressionGSE21033_1H_VS_12H_POLYIC_STIM_DC_UP

MTG2 ATL1 RASGRP1 IGF1R TLE6 HELZ AKT1

1.81e-051761217M7725
CoexpressionGSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP

KAT6A HLCS FAM13B TBC1D9 PTPRC RASGRP3 VAV2

3.98e-051991217M6420
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

2.25e-09901219PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G NALF2 TBC1D3K TBC1D3F

4.01e-0721312110PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G NALF2 TBC1D3K TBC1D3F

4.01e-0721312110PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B SLITRK2 TBC1D3G TBC1D3K TBC1D3F

1.28e-0624212110PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PLCG2 TBC1D3G TBC1D3K TBC1D3F

1.52e-0532012110PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

3.40e-052811219PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

3.40e-052811219PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

CPPED1 TBC1D3 NRAP TBC1D3H TBC1D3L TBC1D3D MYO9A TBC1D3C TBC1D3B GSTA1 GSTA2 RAB11FIP5 ARHGAP8 TBC1D3G VAV2 TBC1D3K TBC1D3F

9.44e-05104912117PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSD2 AOC1 FAT3 CHAD CMYA5 ZFHX3 PLCG2 PLCH1

1.75e-081611248f5df8c6a340d5026726804b103e32137f363ca40
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)|Cerebellum / BrainAtlas - Mouse McCarroll V32

KIF6 NRAP KLHL40 ADGRV1 KCNU1 TLE6

2.94e-07961246a48235df1f5526ce3ffc4c0c2ba038eb20229c55
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

KIF6 NRAP KLHL40 ADGRV1 KCNU1 TLE6

2.94e-079612460fc179af7370a29b7bd5d81e1302a479ae72f196
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf|Cerebellum / BrainAtlas - Mouse McCarroll V32

KIF6 NRAP KLHL40 ADGRV1 KCNU1 TLE6

2.94e-07961246c301ecfd67ece8bb12be1b94b614957a58046457
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2|Cerebellum / BrainAtlas - Mouse McCarroll V32

KIF6 NRAP KLHL40 ADGRV1 KCNU1 TLE6

2.94e-079612467d402d543ff159c9bb84c00b083e6e18fc0ff786
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSD2 AOC1 FAT3 CMYA5 TTC13 PLCG2 ARHGAP8

4.12e-07165124734fd00be2b28716c871ad9fb356de84a299a0c01
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

KIF6 NRAP KLHL40 ADGRV1 KCNU1 TLE6

8.54e-07115124615b2c11225802cc15c01165d84a755432f02d82f
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

KIF13B UBR2 VPS13C XPO1 PTPRC MCM9 PRKDC

1.10e-0619112479454f642c3621370fa23640b631301346b300950
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

KIF6 CFAP251 IQCH ECT2L CFAP43 GSTA1 PLCH1

1.14e-061921247d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

KIF6 CFAP251 IQCH ECT2L CFAP43 GSTA1 PLCH1

1.14e-061921247eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSNAXIP1 KIF6 CFAP251 IQCH ECT2L CFAP43 SYNE2

1.35e-06197124774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UBR2 VPS13C XPO1 PTPRC SYNE2 HELZ PLCG2

1.50e-06200124712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSNAXIP1 KIF6 IQCH TSHR CFAP43 GSTA2

4.67e-0615412469ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSNAXIP1 KIF6 IQCH TSHR CFAP43 GSTA2

4.67e-06154124658072ce422d09f2de602580325eaac6c4ec6c136
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRAP KLHL40 FAT3 ECT2L CMYA5 PLCH1

7.43e-061671246d78356bf0c473816dbabaee51984940bd822f84e
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B SLC38A4 IBTK IGF1R PTPRC ZFHX3

8.80e-061721246d354424c1f861b6607dfd63b9724f4c237b30275
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B MYO9A VPS13C CKAP5 CMYA5 IBTK

1.00e-051761246749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NAT1 KIF6 CFAP251 IQCH ECT2L CFAP43

1.18e-051811246dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

TSNAXIP1 NAT1 KIF6 CFAP251 ECT2L CFAP43

1.21e-0518212467ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

UBR2 VPS13C XPO1 PTPRC MCM9 PRKDC

1.33e-051851246a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

UBR2 VPS13C XPO1 PTPRC MCM9 PRKDC

1.37e-0518612468571956890fc9894d766ba294a28e376b4aba428
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

KIF6 CFAP251 CFAP43 GSTA1 GSTA2 PLCH1

1.41e-051871246f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

TSNAXIP1 NAT1 KIF6 CFAP251 ECT2L CFAP43

1.50e-051891246b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

KIF6 CFAP251 IQCH ECT2L CFAP43 PLCH1

1.50e-0518912463e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLC38A4 RAB11A PLXND1 RASGRP3 RAB11FIP5 TNXB

1.59e-051911246d25ac3206fe205a100cfee26431ff32c14c1938f
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIF6 CFAP251 IQCH ECT2L CFAP43 GSTA1

1.59e-0519112461c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

KIF6 CFAP251 IQCH ECT2L CFAP43 PLCH1

1.64e-051921246354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

KIF6 CFAP251 IQCH ECT2L CFAP43 PLCH1

1.69e-051931246ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYO9A UNC13D ADGRV1 PLA2G4B SYNE2 SMARCA4

1.90e-0519712463d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

VPS13C KAT6A TBC1D9 PTPRC ZFHX3 KAT6B

1.95e-051981246af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

VPS13C KAT6A TBC1D9 PTPRC ZFHX3 KAT6B

1.95e-051981246ad39cce004867f083f8da1954e0cf5a263815184
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

VPS13C KAT6A TBC1D9 PTPRC ZFHX3 KAT6B

1.95e-05198124662cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSNAXIP1 NAT1 KIF6 CFAP251 ECT2L CFAP43

2.07e-052001246af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYO9A UNC13D ADGRV1 PLA2G4B SYNE2 SMARCA4

2.07e-0520012468683445ad5b70748c4a1f12eb77d47623085147e
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSNAXIP1 NAT1 KIF6 CFAP251 ECT2L CFAP43

2.07e-05200124673ac1cf40ddd764be1100cbfaaa29563665457d8
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

UBR2 ARRB2 PTPRC USP32 PRKDC

6.51e-051511245b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellCiliated_cells-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

TSNAXIP1 CFAP251 CFAP43 TBC1D3B GSTA1

7.14e-0515412453b938e23324f7edb56797b4a76fb96ff588142cf
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAT1 CHAD TSHR GSTA1

7.76e-058112442c58dbad21e0fbe46b005bcaf45139d098a2057a
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAT1 CHAD TSHR GSTA1

7.76e-05811244a0b45dc22077805eba94689568b874415f515d61
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAT1 CHAD TSHR GSTA1

7.76e-05811244571884bcf4282053c6170609ae0c794a6df05cd9
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 CHAD ENPP5 ZFHX3 PLCG2

9.07e-05162124580619a93c57fe16daf91dc571874ef9ac888953d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

RASGRP1 PTPRC PKD2L2 PRKACB RPS6KA6

1.05e-041671245063ec29b32e40aaa138a691da3a79ee8eef0c2be
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT3 CHAD CMYA5 ZFHX3 PLCG2

1.08e-0416812458072d0496b7b730c4601009eaa69ec5366d26d73
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C ATL1 PRKACB ZFHX3 PLCH1

1.08e-041681245d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 CCNP CMYA5 ZFHX3 PLCG2

1.11e-04169124505e12524d68d409fed386ffad233305683b4575b
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAB11A CHAD CMYA5 TBC1D9 RASGRP3

1.14e-04170124555fe16d98ea284d05fb899888e4569c685644c7b
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A FAT3 CPA1 PLXND1 TLE6

1.27e-041741245165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TSNAXIP1 KIF6 AOC1 CFAP43 PLCH1

1.27e-041741245f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A FAT3 CPA1 PLXND1 TLE6

1.27e-0417412454289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TSNAXIP1 KIF6 AOC1 CFAP43 PLCH1

1.30e-041751245c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellwk_08-11-Hematologic_Lymphocytic-B-Large_pre-B|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TSHR RASGRP1 PTPRC GNA15 PLCG2

1.34e-04176124578417a5ac2e45e97e7b4c56c78c25879a1b58f97
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GSTA2 ARRB2 PRKACA GNA15 PLCH1

1.37e-0417712452dd6dd5193bda9ba1c6b299ec47890fdc92f88b1
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 FAT3 CCNP ZFHX3 PLCG2

1.41e-041781245f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.41e-041781245de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASIC1 SACS ADAM33 PLCH1 MSLN

1.45e-041791245adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|368C / Donor, Lineage, Cell class and subclass (all cells)

TSNAXIP1 ECT2L CFAP43 GSTA1 GSTA2

1.52e-0418112455a4574f1bfd0b4ca78da7effda43420857e17296
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|368C / Donor, Lineage, Cell class and subclass (all cells)

TSNAXIP1 ECT2L CFAP43 GSTA1 GSTA2

1.52e-041811245a4e891603645f694687e68e585744ddc1a3c8697
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.56e-041821245fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

FAT3 ECT2L RPS6KA6 ADAM33 MSLN

1.56e-041821245ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.65e-0418412455daff849625f2f41d56615569c0ed59cd733b34c
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 CMYA5 ZFHX3 PLCG2 ARHGAP8

1.69e-041851245686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.69e-04185124530f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 ECT2L CFAP43 GSTA1 GSTA2

1.73e-041861245f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 ECT2L CFAP43 GSTA1 GSTA2

1.77e-0418712456fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO9A UNC13D ADGRV1 PLA2G4B SYNE2

1.77e-04187124558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.77e-0418712459e10ed56090d82589bc457788282f664b70ace4b
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.82e-04188124561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.82e-04188124534b11f72ca73153d02edcd09b38983ad1a504659
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

TSNAXIP1 CFAP251 ECT2L CFAP43 GSTA1

1.82e-0418812459a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.86e-041891245a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAB11A CHAD PLXND1 RASGRP3 SMARCA2

1.86e-041891245feedac2751ed770f80bc56fec31662b5b3826f58
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSNAXIP1 CFAP251 AOC1 CHAD CFAP43

1.86e-04189124538cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

NAT1 KIF6 CFAP251 ECT2L CFAP43

1.86e-04189124527329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellmoderate-Epithelial-Ciliated-diff|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP251 CFAP36 CFAP43 GSTA1 GSTA2

1.96e-0419112456cdc6a0c0a1ce5a1ef550832319847f62e718975
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 CFAP36 CFAP43 GSTA1 GSTA2

1.96e-0419112453e84c453e8a151c42808fe2935f1d732e180008c
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

CFAP251 ECT2L CFAP43 GSTA1 GSTA2

1.96e-041911245ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIF6 CFAP251 IQCH ECT2L CFAP43

1.96e-041911245e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIF6 CFAP251 IQCH ECT2L CFAP43

1.96e-0419112459d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

CFAP251 ECT2L CFAP43 GSTA1 GSTA2

1.96e-0419112456228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A TTC14 ADGRV1 SYNE2 RPS6KA6

2.01e-041921245ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBR2 KAT6A PRKACB ZFHX3 PLCG2

2.01e-0419212451ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFAP251 ECT2L CFAP43 KIF3A GSTA1

2.05e-041931245c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

KIF6 CFAP251 IQCH ECT2L CFAP43

2.05e-0419312450e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

CKAP5 ADGRV1 PBRM1 USP32 PRKDC

2.05e-041931245abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C PLXND1 RASGRP1 PTPRC SMARCA4

2.05e-041931245a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CHAD TBC1D9 RASGRP3 PLCG2 VAV2

2.05e-041931245de0213f2105b814f38ffbfd004ea7603230eed68
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

CDH23 PLXND1 ARRB2 KCNU1 VAV2

2.10e-041941245800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TSNAXIP1 CFAP251 ECT2L CFAP43 PLCH1

2.10e-0419412451ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

KIF6 CFAP251 CFAP43 GSTA1 PLCH1

2.10e-041941245958e648138676d46698090b4046cb484083ae449
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSNAXIP1 CFAP251 ECT2L CFAP43 PLCG2

2.10e-0419412454a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP251 ECT2L CFAP43 SYNE2 PLCH1

2.15e-041951245fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

CFAP251 ECT2L CFAP43 SYNE2 PLCH1

2.15e-04195124521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP251 ECT2L CFAP43 SYNE2 PLCH1

2.15e-041951245eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF6 ECT2L CFAP43 GSTA1 GSTA2

2.15e-04195124507a6bcef6af93ed87df455dee624037cb75e011a
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP251 CFAP43 GSTA1 SYNE2 PLCH1

2.21e-041961245af4cdc61830685a888a1209826c23bcf54a43084
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC38A4 TSHR TBC1D9 RASGRP3 PLCG2

2.21e-041961245fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP251 CFAP43 GSTA1 SYNE2 PLCH1

2.21e-0419612456d02d494196e3f857d53eea46d9419690d43beca
ToppCellTracheal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FAT3 FAM13B USP32 ADAM33 TNXB

2.26e-041971245d7cef7881abd807a679432766ced609a6efd1067
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC14 PTPRC SYNE2 SMARCA2 PLCG2

2.26e-04197124557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellTracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FAT3 FAM13B USP32 ADAM33 TNXB

2.26e-04197124520a5958512bdb99daeb8f4d244df53e4f048f879
Diseasealcohol use disorder (implicated_via_orthology)

PSD2 NDUFS2 PBRM1 KCNU1 PRKACA PRKACB SMARCA2 SMARCA4 AKT1

7.12e-081951149DOID:1574 (implicated_via_orthology)
DiseaseIntrahepatic Cholangiocarcinoma

PBRM1 PRKACA PRKACB MSLN

2.12e-06241144C0345905
DiseaseExtrahepatic Cholangiocarcinoma

PBRM1 PRKACA PRKACB MSLN

2.12e-06241144C3805278
DiseaseCholangiocarcinoma

PBRM1 PRKACA PRKACB MSLN

2.96e-06261144C0206698
DiseaseProstatic Neoplasms

NAT1 KAT6A UNC13D XPO1 GSTA1 PTPRC PRKACB ENPP5 AKT1 ZFHX3 PRKDC

2.77e-0561611411C0033578
DiseaseMalignant neoplasm of prostate

NAT1 KAT6A UNC13D XPO1 GSTA1 PTPRC PRKACB ENPP5 AKT1 ZFHX3 PRKDC

2.77e-0561611411C0376358
DiseaseDiGeorge syndrome (implicated_via_orthology)

KAT6A PLXND1 CRKL

5.20e-05191143DOID:11198 (implicated_via_orthology)
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

ECT2L PTPN2 PTPRC SMARCA4

5.35e-05531144C1961099
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA2 SMARCA4

1.47e-0451142C3281201
Diseaseurate measurement, bone density

TRPM6 NAT1 KIF6 DSCAM MTG2 ATL1 PRKACB PRKDC KAT6B TNXB

1.48e-0461911410EFO_0003923, EFO_0004531
Diseasemean platelet volume

CFAP251 AOC1 KIAA0232 UNC13D PLXND1 CRKL PTPRC SYNE2 MCM9 ZNF778 TTC13 PLCG2 ULK2

1.61e-04102011413EFO_0004584
Diseaselung non-small cell carcinoma (is_implicated_in)

NAT1 XPO1 PBRM1 SMARCA4 ZFHX3

2.10e-041391145DOID:3908 (is_implicated_in)
DiseaseCushing Syndrome

CDH23 PRKACB

2.20e-0461142C0010481
Diseaseintestinal cancer (implicated_via_orthology)

RAB11B RAB11A PTPN2

2.57e-04321143DOID:10155 (implicated_via_orthology)
Diseasepalmitoyl dihydrosphingomyelin (d18:0/16:0) measurement

SYNE2 SMARCA4

3.07e-0471142EFO_0800400
Diseasesex interaction measurement, Crohn's disease

XPO1 PTPN2 RASGRP1

3.97e-04371143EFO_0000384, EFO_0008343
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCA2 SMARCA4

5.23e-0491142DOID:0050340 (implicated_via_orthology)
Diseaseatrial fibrillation

XPO1 FAM13B CRK IGF1R PKD2L2 SYNE2 ZFHX3

6.11e-043711147EFO_0000275
DiseaseAdrenal Gland Neoplasms

TSHR PRKACA

7.95e-04111142C0001624
DiseaseAdrenal Cancer

TSHR PRKACA

7.95e-04111142C0750887
Diseasepancreatic cancer (is_implicated_in)

NAT1 IGF1R AKT1 MSLN

9.52e-041121144DOID:1793 (is_implicated_in)
DiseaseN-acetylputrescine measurement

NAT1 AOC1

9.52e-04121142EFO_0800127
Diseaselate-onset Alzheimers disease

FAT3 CKAP5 STK31 USP32 TRPM1 PLCG2

9.74e-042921146EFO_1001870
Diseaseserum IgG glycosylation measurement

DSCAM VPS13C KIAA0232 WRN TSHR PLCG2 PLCH1 VAV2

9.85e-045231148EFO_0005193
DiseaseCoffin-Siris syndrome

SMARCA2 SMARCA4

1.12e-03131142C0265338
Diseaselymphocyte percentage of leukocytes

UBR2 AOC1 CDH23 CRK ARRB2 PTPRC HELZ ZNF778 PRKDC

1.13e-036651149EFO_0007993
DiseaseSmall cell carcinoma of lung

STK31 SMARCA4 AKT1

1.21e-03541143C0149925
Diseasesex interaction measurement, inflammatory bowel disease

PTPN2 RASGRP1 TNXB

1.27e-03551143EFO_0003767, EFO_0008343
Diseaseovarian cancer (is_implicated_in)

GSTA1 AKT1 MSLN

1.34e-03561143DOID:2394 (is_implicated_in)
Disease1,3,7-trimethylurate measurement

GSTA1 GSTA2

1.50e-03151142EFO_0021172
DiseaseMalignant Neoplasms

NAT1 WRN AKT1 MSLN

1.56e-031281144C0006826
Diseasethyroid volume

IGF1R SMARCA2

1.71e-03161142EFO_0004865
Diseasesphingomyelin 14:0 measurement

SYNE2 ZFHX3

1.94e-03171142EFO_0010390
Diseaselevel of Sphingomyelin (d32:1) in blood serum

SYNE2 SMARCA4

1.94e-03171142OBA_2045173
DiseaseC-X-C motif chemokine 16 measurement

CDH23 ARRB2

2.17e-03181142EFO_0010911
DiseaseC-C motif chemokine 3 measurement

TBC1D3B PLCG2

2.17e-03181142EFO_0008051
DiseaseMeningioma

WRN AKT1

2.42e-03191142C0025286
Diseasebreast size

VPS13C KCNU1 KAT6B

2.44e-03691143EFO_0004884
Diseaseneutrophil count

UBR2 DSCAM RAB11A CDH23 TSHR XPO1 CRK PTPRC AKT1 GNA15 PRKDC TNXB ATP6V0A2

2.65e-03138211413EFO_0004833
DiseaseCCL4 measurement

TBC1D3 TBC1D3F

2.69e-03201142EFO_0004751
Diseaseprostate adenocarcinoma (is_implicated_in)

IGF1R AKT1

2.69e-03201142DOID:2526 (is_implicated_in)
DiseaseSevere Combined Immunodeficiency

PTPRC PRKDC

2.69e-03201142C0085110
Diseasechronic myeloid leukemia (is_implicated_in)

CRKL AKT1

2.96e-03211142DOID:8552 (is_implicated_in)
Diseasevenous thromboembolism, plasminogen activator inhibitor 1 measurement

CKAP5 PLCG2

2.96e-03211142EFO_0004286, EFO_0004792
DiseaseParoxysmal atrial fibrillation

XPO1 IGF1R SYNE2 ZFHX3

3.20e-031561144C0235480
Diseasefamilial atrial fibrillation

XPO1 IGF1R SYNE2 ZFHX3

3.20e-031561144C3468561
DiseasePersistent atrial fibrillation

XPO1 IGF1R SYNE2 ZFHX3

3.20e-031561144C2585653
Diseasehemoglobin measurement, mean corpuscular hemoglobin

RAB11A PTPRC

3.25e-03221142EFO_0004509, EFO_0004527
DiseaseCorneal astigmatism

ITPRIPL2 KCNU1 VAV2

3.34e-03771143EFO_1002040
DiseaseAtrial Fibrillation

XPO1 IGF1R SYNE2 ZFHX3

3.50e-031601144C0004238
DiseaseNeoplasm of the genitourinary tract

AKT1 ZFHX3

3.86e-03241142cv:C0042065

Protein segments in the cluster

PeptideGeneStartEntry
LDYLHSEKNVVYRDL

AKT1

261

P31749
LHSDLLEDSKYRKIY

NAT1

176

P18440
HKIYEEKYADTNILL

ADAM5

106

Q6NVV9
DEIIHKYLYELEHAL

CFAP43

576

Q8NDM7
KYLYELEHALSSAVL

CFAP43

581

Q8NDM7
TYHTLEEIYDFLDLL

CPA1

121

P15085
SKLTYTEIHQEYKEL

CFAP36

46

Q96G28
HLLTLSLDLYYTEDE

RASGRP1

411

O95267
YERKLTLEEIYELHA

ADGRV1

1486

Q8WXG9
LELIHRYVELLDKYF

AP1S1

81

P61966
YLELYIVADHTLFLT

ADAM33

211

Q9BZ11
YEHSVTLESLLYLIE

ECT2L

316

Q008S8
HKYLTVKDYLRDIDL

ATAD2

1041

Q6PL18
AEYALLYHTLQEATK

AOC1

146

P19801
DLTELTYLYLDHNKV

CHAD

121

O15335
GDTLYLAVHLLDSYL

CCNP

126

Q9H8S5
KELDYEISHGRYTLI

CDH23

1696

Q9H251
RSLHLEASLDKELYY

ARRB2

196

P32121
SLIHIDYYLQVSLKA

ARRDC1

256

Q8N5I2
TEELYSYLKEFIHIL

ACTR10

61

Q9NZ32
EYDLLRSYKDHLEVL

CFAP251

771

Q8TBY9
LEFYKIHYLDTTTLI

CRK

101

P46108
GALLVYDIAKHLTYE

RAB11A

86

P62491
GALLVYDIAKHLTYE

RAB11B

86

Q15907
KLYTVDLESGLHYLL

QSOX2

321

Q6ZRP7
KYYHLTHDELISLLL

RAB11FIP5

596

Q9BXF6
ADIHLVELLYYVEEL

GSTA1

156

P08263
DELVLYYKKILSLHA

IQCH

501

Q86VS3
LSEDVKSYYTVHLLQ

PTPN2

146

P17706
LLAKLFLDHKTLYYD

KAT6B

806

Q8WYB5
TQRLLHSEAYLKYIE

PBRM1

1601

Q86U86
IVLTFEYLHSLDLIY

PRKACA

151

P17612
TIKELDLYLAYFVHT

NFIX

171

Q14938
YTEVLDLSYLLDHLA

GPN2

196

Q9H9Y4
LASDLDYRKKLHEYT

NRAP

646

Q86VF7
HSDILKVILDYLYTD

IBTK

816

Q9P2D0
LLSYEDLELAVGHLY

MMS19

476

Q96T76
EEYLLFDSDKLSHLI

FAM13B

416

Q9NYF5
DIDSYILYHLLEDSA

HLCS

191

P50747
ADIHLVELLYYVEEL

GSTA2

156

P09210
EGYLHILLISKAEDY

IGF1R

56

P08069
SLLTIALHGKLEYYT

PLXND1

1446

Q9Y4D7
VLSLLLHDSYDYDLQ

KIAA0232

61

Q92628
KYLDDIHLSELTHFY

KIAA0232

496

Q92628
KTAKYNYDILLLEHS

MUC19

8321

Q7Z5P9
ELDQYLDKDHYTLID

ENPP5

251

Q9UJA9
LLTEAKYINLSLHYL

KIF6

266

Q6ZMV9
YEQLDVLKHKLDELY

MSLN

346

Q13421
HLLLIAIEYKSLFTD

KCNU1

551

A8MYU2
LHYLYTSEIALDEAS

KLHL40

86

Q2TBA0
SDILYVISKTVDYLH

RPS6KA6

521

Q9UK32
LVLHKYLQAEEYSIR

NALF2

266

O75949
YSQEDVDKLLHLTHY

PLA2G4B

741

P0C869
ESLVELVSYYEKHSL

PLCG2

711

P16885
LLDSAVYYLSHLERI

GNA15

156

P30679
EFYKIHYLDTTTLIE

CRKL

86

P46109
VDLSHVYLAYTEESL

KIF3A

646

Q9Y496
YQSRLHDLLYIEEIA

HELZ

456

P42694
LHRGTEKLIEYKTYL

NDUFS2

116

O75306
DTLLLEKHADYIASY

RABGGTB

16

P53611
LAKLFLDHKTLYYDV

KAT6A

596

Q92794
EYLKLLFTLLSEEEY

CKAP5

1266

Q14008
IVLTFEYLHSLDLIY

PRKACB

151

P22694
LESEIDELYIQYIKH

ATL1

421

Q8WXF7
IYFEKYILKDDILHD

CMYA5

3236

Q8N3K9
REHTDLYLLNITIYD

FAT3

791

Q8TDW7
EKIVHRYYSLDELSE

CPPED1

286

Q9BRF8
SVQYLYRELLVHLDD

DNAAF5

786

Q86Y56
ENLSYDAKLEHLIYL

SACS

3486

Q9NZJ4
GLSILLESYYEHEVR

ITPRIPL2

96

Q3MIP1
YVSEYHKNDILLILK

MCM9

16

Q9NXL9
LLIKHVVEEDSGYYL

DSCAM

751

O60469
ELLVYYLKEHTLIGS

KIF13B

461

Q9NQT8
LLTTYEYIIKDKHIL

SMARCA2

826

P51531
VHYETLALELKKLYL

SYNE2

4566

Q8WXH0
TLSLDLYHTEDDIYK

RASGRP3

361

Q8IV61
LYHTEDDIYKLSLVL

RASGRP3

366

Q8IV61
LLTTYEYIIKDKHIL

SMARCA4

856

P51532
YKNDLLEYSSLDLLH

SLITRK2

391

Q9H156
LLLHLKVLYDAYAEA

MTG2

381

Q9H4K7
EEYLSDIAYKSTEHL

WRN

411

Q14191
DELLHAYSKVYTLDI

SLC38A4

396

Q969I6
KQRELLHILLAYEEY

TBC1D3L

166

B9A6J9
YLLNLKEHLEDIYVG

B3GALT9

196

A8MXE2
LELFDYAYEVIKHKL

ASIC1

451

P78348
EINTYKAIHLDLEEY

CNDP1

306

Q96KN2
VDLYILTYQAEKALH

CNOT10

156

Q9H9A5
VDLTNHLEYTLKTYI

STK31

346

Q9BXU1
KQRELLHILLAYEEY

TBC1D3B

166

A6NDS4
KQRELLHILLAYEEY

TBC1D3H

166

P0C7X1
LVYLTHLDYVDTERI

XPO1

461

O14980
QLYHAEIDALYKDLT

TTC13

716

Q8NBP0
YLLKEHLKTYTEEQV

ZNF778

686

Q96MU6
YIRTSYDTKLDHLLH

TRPM6

111

Q9BX84
DDTIRYLSLHDNKYI

WDR82

86

Q6UXN9
KQRELLHILLAYEEY

TBC1D3F

166

A6NER0
LTFEKSRYETYIHLL

PSD2

701

Q9BQI7
LSGLESDHRYLVTLY

TNXB

1936

P22105
ELEELYALFKAEHLT

TBC1D9

826

Q6ZT07
SASEEYLKENHILEY

TTC41P

916

Q6P2S7
YLKENHILEYATEIS

TTC41P

921

Q6P2S7
IDRYHEKLAVSLYSS

TTC14

196

Q96N46
VSYLKKISLDYHEIE

VPS13C

956

Q709C8
KQRELLHILLAYEEY

TBC1D3E

166

A0A087X179
LFLYAVELEKELHYI

PKD2L2

596

Q9NZM6
DLYLLLLSYSDKKDH

PLCH1

216

Q4KWH8
AILELHYSQELSLLY

PRKDC

3076

P78527
SHELDHQRLLEYLKY

ARHGAP8

46

P85298
YHISLIDIGLVLEYL

TRPM1

526

Q7Z4N2
EDIVYRYHKAALLLE

ULK2

986

Q8IYT8
HSDKIIRLYDYEITD

TTK

581

P33981
KQRELLHILLAYEEY

TBC1D3D

166

A0A087WVF3
LLRHLYAKDDYELID

TTC37

1526

Q6PGP7
GYSYELKEIIELLFH

VAV2

441

P52735
LRKNLAEEYLHYLSE

TSNAXIP1

176

Q2TAA8
EESAVLALYKTLHQY

UBR2

1476

Q8IWV8
KQRELLHILLAYEEY

TBC1D3G

166

Q6DHY5
KQRELLHILLAYEEY

TBC1D3

166

Q8IZP1
SIALLVVLYKIYDLH

PTPRC

591

P08575
QRALLYEDALYTVLH

UNC13D

51

Q70J99
KQRELLHILLAYEEY

TBC1D3K

166

A0A087X1G2
YLTLLDDEDHKLEYL

USP32

676

Q8NFA0
KQRELLHILLAYEEY

TBC1D3I

166

A0A087WXS9
KQRELLHILLAYEEY

TBC1D3C

166

Q6IPX1
AAELESIYYSLHKIQ

TLE6

51

Q9H808
QDLYTVLHKTEDYLR

ATP6V0A2

271

Q9Y487
DYYTNSLEKLRLHTV

ZFHX3

1046

Q15911
YLLLIASVDLYTHSE

TSHR

466

P16473
EKYLLEKSRLVYQEH

MYO9A

316

B2RTY4