Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	nuclear speck	NRDE2 SETD1B SRSF4 SRSF6 PNN ZC3H13 TRIP12 EFTUD2	1.04e-05	431	52	8	GO:0016607
GeneOntologyCellularComponent	nuclear body	NRDE2 TRIM25 SETD1B SRSF4 SRSF6 ATRX PNN ZC3H13 TRIP12 EFTUD2	6.53e-05	903	52	10	GO:0016604
GeneOntologyCellularComponent	transcription elongation factor complex	CCNT1 AFF1 MLLT3	3.67e-04	56	52	3	GO:0008023
Domain	CCDC74_C	CCDC74B CCDC74A	7.02e-06	2	50	2	PF14917
Domain	CCDC74	CCDC74B CCDC74A	7.02e-06	2	50	2	IPR033226
Domain	CCDC74_C	CCDC74B CCDC74A	7.02e-06	2	50	2	IPR029422
Domain	-	TRIM25 SH3RF1 ATRX MYCBP2 PHRF1 BSN	1.21e-03	449	50	6	3.30.40.10
Domain	RING	TRIM25 SH3RF1 ATRX MYCBP2 PHRF1	1.31e-03	305	50	5	SM00184
Domain	Znf_RING/FYVE/PHD	TRIM25 SH3RF1 ATRX MYCBP2 PHRF1 BSN	1.36e-03	459	50	6	IPR013083
Domain	Znf_RING	TRIM25 SH3RF1 ATRX MYCBP2 PHRF1	1.75e-03	326	50	5	IPR001841
Domain	Znf_FYVE_PHD	ATRX PHRF1 BSN	7.15e-03	147	50	3	IPR011011
Domain	ZF_RING_1	TRIM25 SH3RF1 MYCBP2 PHRF1	7.58e-03	291	50	4	PS00518
Domain	ZF_RING_2	TRIM25 SH3RF1 MYCBP2 PHRF1	8.22e-03	298	50	4	PS50089
Domain	AAA	ORC1 RFC1	8.55e-03	52	50	2	PF00004
Domain	zf-RING_2	MYCBP2 PHRF1	8.55e-03	52	50	2	PF13639
Domain	ATPase_AAA_core	ORC1 RFC1	9.20e-03	54	50	2	IPR003959
Domain	Znf_RING_CS	TRIM25 SH3RF1 PHRF1	9.47e-03	163	50	3	IPR017907
Pathway	KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION	CCNT1 AFF1 MLLT3	4.50e-05	26	38	3	M47439
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ORC1 PRR12 TICRR YAF2 SRSF4 SRSF6 ATRX PNN ZC3H13 PHRF1 AATF RFC1 TRIP12 EFTUD2	5.62e-09	1294	53	14	30804502
Pubmed	Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.	CCNT1 AFF1 MLLT3	6.66e-08	6	53	3	21896721
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SRSF6 ATRX PNN MYCBP2 ZC3H13 PHRF1 AFF1 RFC1 TRIP12 EFTUD2	2.31e-07	774	53	10	15302935
Pubmed	Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure.	CCNT1 AFF1 MLLT3	2.79e-07	9	53	3	24565118
Pubmed	A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.	CCNT1 AFF1 MLLT3	3.98e-07	10	53	3	20153263
Pubmed	Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1.	CCNT1 SRSF4 SRSF6	3.98e-07	10	53	3	10983978
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	PRR12 CCNT1 SRSF4 SRSF6 PNN ZC3H13 AATF RFC1 TRIP12 EFTUD2	5.26e-07	847	53	10	35850772
Pubmed	HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.	CCNT1 AFF1 MLLT3	5.47e-07	11	53	3	20471949
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SRSF4 PNN MYCBP2 ZC3H13 PHRF1 WDR46 AATF RFC1 TRIP12	5.82e-07	653	53	9	22586326
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ORC1 CCNT1 TRIM25 SETD1B SRSF6 PNN MYCBP2 WDR46 AATF RFC1 TRIP12 EFTUD2	6.96e-07	1353	53	12	29467282
Pubmed	Transcriptional and posttranscriptional regulation of HIV-1 gene expression.	CCNT1 AFF1 MLLT3	9.45e-07	13	53	3	22355797
Pubmed	MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.	CCNT1 AFF1 MLLT3	1.20e-06	14	53	3	20854876
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	PRR12 SRSF4 SRSF6 PNN MYCBP2 ZC3H13 EFTUD2	1.25e-06	361	53	7	30344098
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CCNT1 SRSF4 SRSF6 ATRX PNN ZC3H13 AATF RFC1 TRIP12 EFTUD2	1.54e-06	954	53	10	36373674
Pubmed	Regulation of alternative splicing by SRrp86 and its interacting proteins.	SRSF4 SRSF6 PNN EFTUD2	1.79e-06	57	53	4	14559993
Pubmed	Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3.	SRSF4 SRSF6	2.28e-06	2	53	2	20685659
Pubmed	Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.	AFF1 MLLT3	2.28e-06	2	53	2	8506309
Pubmed	MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.	AFF1 MLLT3	2.28e-06	2	53	2	28114278
Pubmed	A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer.	SRSF4 SRSF6	2.28e-06	2	53	2	7651409
Pubmed	CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.	CCDC74B CCDC74A	2.28e-06	2	53	2	31521166
Pubmed	MLL fusion partners AF4 and AF9 interact at subnuclear foci.	AFF1 MLLT3	2.28e-06	2	53	2	14603337
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	TGFB2 CCNT1 YAF2 SRSF4 SRSF6 PNN AFF1 MLLT3 RFC1 TRIP12 EFTUD2	2.30e-06	1247	53	11	27684187
Pubmed	The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.	CCNT1 AFF1 MLLT3	2.68e-06	18	53	3	21030982
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	SRSF4 SRSF6 PNN PHRF1 AATF EFTUD2	2.76e-06	259	53	6	30404004
Pubmed	BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing.	SRSF4 PNN EFTUD2	3.18e-06	19	53	3	25263594
Pubmed	Lost in transcription: molecular mechanisms that control HIV latency.	CCNT1 AFF1 MLLT3	3.18e-06	19	53	3	23518577
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	CCNT1 SRSF4 SRSF6 PNN ZC3H13 WDR46 AATF RFC1 TRIP12 SREK1IP1 EFTUD2	3.92e-06	1318	53	11	30463901
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NRDE2 ZBTB38 SRSF4 SRSF6 PNN MYCBP2 MAP6 ZC3H13 TRIP12 EFTUD2	4.71e-06	1082	53	10	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NRDE2 TICRR ATRX MAP6 ZC3H13 TMEM131L AFF1 P2RY14 AATF TRIP12	4.79e-06	1084	53	10	11544199
Pubmed	The Role of RNA Polymerase II Elongation Control in HIV-1 Gene Expression, Replication, and Latency.	CCNT1 AFF1 MLLT3	5.04e-06	22	53	3	22567366
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	SRSF4 SRSF6 PNN ZC3H13 EFTUD2	6.07e-06	169	53	5	23084401
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CEP350 CCNT1 SRSF4 SRSF6 PNN AFF1 MLLT3 EFTUD2	9.80e-06	695	53	8	23602568
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	TRIM25 MYCBP2 TRIP12	1.07e-05	28	53	3	35474067
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	CCNT1 TRIM25 SRSF4 SRSF6 PNN ZC3H13 RFC1 EFTUD2	1.18e-05	713	53	8	29802200
Pubmed	Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4.	AFF1 MLLT3	1.36e-05	4	53	2	25282333
Pubmed	Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells.	SRSF4 PNN	1.36e-05	4	53	2	14578391
Pubmed	Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing.	AFF1 MLLT3	1.36e-05	4	53	2	17581865
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	TRIM25 MYCBP2 PHRF1 TRIP12	1.38e-05	95	53	4	29643511
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	CEP350 PNN WDR46 AATF RFC1	1.73e-05	210	53	5	16565220
Pubmed	DBC1, p300, HDAC3, and Siah1 coordinately regulate ELL stability and function for expression of its target genes.	CCNT1 AFF1 MLLT3	1.93e-05	34	53	3	32152128
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CEP350 TRIM25 SRSF6 PNN MYCBP2 WDR46 AATF TRIP12 EFTUD2	2.22e-05	1024	53	9	24711643
Pubmed	Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.	AFF1 MLLT3	2.27e-05	5	53	2	23260655
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SRSF4 PNN RFC1 TRIP12 EFTUD2	2.91e-05	234	53	5	36243803
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	SRSF4 SRSF6 PNN EFTUD2	2.93e-05	115	53	4	17332742
Pubmed	The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.	SRSF4 SRSF6 PNN ZC3H13 EFTUD2	3.22e-05	239	53	5	26641092
Pubmed	Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements.	SRSF4 SRSF6	3.40e-05	6	53	2	17361132
Pubmed	Misguided transcriptional elongation causes mixed lineage leukemia.	CCNT1 AFF1	3.40e-05	6	53	2	19956800
Pubmed	SR proteins: a conserved family of pre-mRNA splicing factors.	SRSF4 SRSF6	3.40e-05	6	53	2	1577277
Pubmed	Characterization of the DOT1L network: implications of diverse roles for DOT1L.	CCNT1 AFF1 MLLT3	3.42e-05	41	53	3	20431927
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	CCNT1 SRSF4 SRSF6 PNN EFTUD2	3.56e-05	244	53	5	29884807
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	CCNT1 TICRR SRSF4 SRSF6 PNN WDR46	3.72e-05	410	53	6	26949251
Pubmed	Nucleolar proteome dynamics.	SRSF6 ATRX WDR46 AATF RFC1 EFTUD2	4.20e-05	419	53	6	15635413
Pubmed	Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.	NRDE2 EFTUD2	4.76e-05	7	53	2	30538148
Pubmed	Remodeling of the myocardium in early trabeculation and cardiac valve formation; a role for TGFβ2.	TGFB2 TNNI3	4.76e-05	7	53	2	24623077
Pubmed	Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.	MYCBP2 RGS12	4.76e-05	7	53	2	36700049
Pubmed	ATRX Promotes DNA Repair Synthesis and Sister Chromatid Exchange during Homologous Recombination.	ATRX RFC1	4.76e-05	7	53	2	29937341
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	TRIM25 SETD1B ATRX MYCBP2 AATF TRIP12	5.50e-05	440	53	6	34244565
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	CCNT1 TRIM25 SRSF6 ATRX RFC1 EFTUD2	5.57e-05	441	53	6	31239290
Pubmed	Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2.	AFF1 MLLT3	6.34e-05	8	53	2	32479599
Pubmed	The SR protein family.	SRSF4 SRSF6	8.15e-05	9	53	2	19857271
Pubmed	Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions.	AFF1 MLLT3	8.15e-05	9	53	2	36036574
Pubmed	Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia.	HOXD4 MLLT3	8.15e-05	9	53	2	12242306
Pubmed	Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors.	SRSF4 SRSF6	8.15e-05	9	53	2	15009664
Pubmed	The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.	CCNT1 PHRF1 MLLT3	9.22e-05	57	53	3	21555454
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	YAF2 SETD1B ATRX MLLT3	9.85e-05	157	53	4	30186101
Pubmed	Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse.	AFF1 MLLT3	1.02e-04	10	53	2	19000783
Pubmed	[Detection of fusion genes resulting from chromosome abnormalities in childhood acute lymphoblastic leukemia].	AFF1 MLLT3	1.02e-04	10	53	2	16215946
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP350 PRR12 SH3RF1 USP37 SH2B1 EFTUD2	1.03e-04	493	53	6	15368895
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP350 NRDE2 TRIM25 MYCBP2 WDR46 AATF TRIP12	1.10e-04	724	53	7	36232890
Pubmed	AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.	CCNT1 AFF1	1.24e-04	11	53	2	24367103
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	SRSF4 SRSF6 PNN EFTUD2	1.34e-04	170	53	4	16159877
Pubmed	The little elongation complex regulates small nuclear RNA transcription.	AFF1 MLLT3	1.49e-04	12	53	2	22195968
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	CCNT1 ATRX PNN AATF RFC1 TRIP12	1.57e-04	533	53	6	30554943
Pubmed	A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).	SRSF4 SRSF6	1.76e-04	13	53	2	20516191
Pubmed	Human mediator subunit MED26 functions as a docking site for transcription elongation factors.	CCNT1 AFF1 MLLT3	1.93e-04	73	53	3	21729782
Pubmed	Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.	SRSF6 ATRX PNN EFTUD2	1.97e-04	188	53	4	29721183
Pubmed	SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.	CCNT1 SRSF4 SRSF6 PNN GOLGA3	2.01e-04	353	53	5	27545878
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	TRIM25 TRIP12	2.05e-04	14	53	2	27626314
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	CEP350 CCNT1 TRIM25 ATRX EFTUD2	2.12e-04	357	53	5	37059091
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SRSF4 SRSF6 PNN ZC3H13 WDR46 AATF EFTUD2	2.15e-04	807	53	7	22681889
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	TRIM25 ATRX PNN MYCBP2 PHRF1	2.15e-04	358	53	5	32460013
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	CCNT1 TRIM25 SRSF4 SRSF6 MYCBP2 RFC1 EFTUD2	2.18e-04	809	53	7	32129710
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SRSF6 PNN MYCBP2 ZC3H13 TRIP12	2.23e-04	361	53	5	26167880
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	CCNT1 PNN AATF RFC1	2.26e-04	195	53	4	19454010
Pubmed	Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication.	ORC1 RFC1	2.36e-04	15	53	2	12393188
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SRSF4 SRSF6 ATRX PNN TRIP12 EFTUD2	2.52e-04	582	53	6	20467437
Pubmed	The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.	PNN USP37 EFTUD2	2.92e-04	84	53	3	26299517
Pubmed	Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.	SRSF6 MAP6 BSN	2.92e-04	84	53	3	19165527
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	PNN MYCBP2 GOLGA3	3.02e-04	85	53	3	16051665
Pubmed	RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis.	TRIM25 TRIP12	3.05e-04	17	53	2	37080995
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	SRSF6 PNN ZC3H13 AATF RFC1 EFTUD2	3.10e-04	605	53	6	28977666
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	CCNT1 PNN TRIP12 GOLGA3 EFTUD2	3.19e-04	390	53	5	17643375
Pubmed	TRIB3‒GSK-3β interaction promotes lung fibrosis and serves as a potential therapeutic target.	TRIM25 TRIP12	3.43e-04	18	53	2	34729304
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	SRSF4 SRSF6 PNN	3.46e-04	89	53	3	22446626
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	TRIM25 RFC1 TRIP12	3.57e-04	90	53	3	35654790
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TRIM25 SRSF6 ATRX MYCBP2 ZC3H13 TMEM131L GOLGA3 ADCY9 EFTUD2	3.77e-04	1487	53	9	33957083
Pubmed	Recruitment of the human TREX complex to mRNA during splicing.	ZC3H13 EFTUD2	4.25e-04	20	53	2	15998806
Pubmed	Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study.	ZBTB38 BSN	4.25e-04	20	53	2	20846217
Pubmed	HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.	CCNT1 MLLT3	4.25e-04	20	53	2	20471948
Pubmed	A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.	MYCBP2 GOLGA3	4.70e-04	21	53	2	24923560
Interaction	DOT1L interactions	ORC1 CCNT1 SRSF4 SRSF6 ATRX PNN ZC3H13 AFF1 MLLT3 AATF RFC1 TRIP12 EFTUD2	1.18e-07	807	53	13	int:DOT1L
Interaction	YWHAE interactions	TICRR BNIP5 YAF2 TRIM25 SRSF4 SH3RF1 SRSF6 MYCBP2 KIF26B RAB3IP TRIP12 RGS12 GOLGA3 PSD4 EFTUD2	5.05e-07	1256	53	15	int:YWHAE
Interaction	YWHAQ interactions	CEP350 TICRR ZBTB38 YAF2 TRIM25 SH3RF1 SRSF6 MYCBP2 KIF26B ZC3H13 RFC1 TRIP12 RGS12 EFTUD2	7.57e-07	1118	53	14	int:YWHAQ
Interaction	MEN1 interactions	PRR12 CCNT1 SETD1B SRSF4 SRSF6 ATRX PNN ZC3H13 WDR46 AATF RFC1 TRIP12 EFTUD2	1.86e-06	1029	53	13	int:MEN1
Interaction	THRAP3 interactions	TRIM25 SRSF4 SRSF6 PNN MYCBP2 TBCK PHRF1 AATF EFTUD2	2.08e-06	443	53	9	int:THRAP3
Interaction	TMSB4Y interactions	ZC3H13 WDR46 AATF TRIP12	3.27e-06	39	53	4	int:TMSB4Y
Interaction	NCBP3 interactions	TRIM25 SRSF4 SRSF6 PNN ZC3H13 AATF	3.32e-06	156	53	6	int:NCBP3
Interaction	GNL2 interactions	TRIM25 SRSF4 SRSF6 ZC3H13 WDR46 AATF RFC1 EFTUD2	7.03e-06	386	53	8	int:GNL2
Interaction	NSD2 interactions	TRIM25 SRSF4 SRSF6 ATRX MYCBP2 WDR46 GOLGA3	7.90e-06	278	53	7	int:NSD2
Interaction	KIF21A interactions	TRIM25 SRSF4 SRSF6 PHRF1 EFTUD2	8.21e-06	105	53	5	int:KIF21A
Interaction	MED26 interactions	CCNT1 TRIM25 ZC3H13 AFF1 MLLT3	9.00e-06	107	53	5	int:MED26
Interaction	RSBN1L interactions	ZBTB38 TRIM25 SRSF4 SRSF6 PNN	1.23e-05	114	53	5	int:RSBN1L
Interaction	RNPS1 interactions	NRDE2 SRSF4 SRSF6 HOXD4 PNN AATF USP37 EFTUD2	1.41e-05	425	53	8	int:RNPS1
Interaction	YWHAG interactions	CEP350 TICRR BNIP5 SH3RF1 PNN MYCBP2 KIF26B ZC3H13 USP37 TRIP12 RGS12 PSD4 EFTUD2	1.52e-05	1248	53	13	int:YWHAG
Interaction	MLLT1 interactions	CCNT1 YAF2 TRIM25 AFF1 MLLT3	1.77e-05	123	53	5	int:MLLT1
Interaction	SIRT7 interactions	TRIM25 SRSF4 PNN MYCBP2 ZC3H13 PHRF1 WDR46 AATF RFC1 TRIP12	2.05e-05	744	53	10	int:SIRT7
Interaction	EAF1 interactions	YAF2 SH3RF1 ATRX AFF1 MLLT3	2.15e-05	128	53	5	int:EAF1
Interaction	CLK3 interactions	CCNT1 TRIM25 SRSF4 SRSF6 PNN ZC3H13	2.37e-05	220	53	6	int:CLK3
Interaction	XRCC6 interactions	ORC1 CCNT1 ZBTB38 YAF2 TRIM25 HOXD4 ATRX PHRF1 RFC1 TRIP12 EFTUD2	2.40e-05	928	53	11	int:XRCC6
Interaction	USP7 interactions	PRR12 BNIP5 ZBTB38 YAF2 TRIM25 SRSF4 TRPA1 ATRX PNN RFC1 BSN TRIP12 EFTUD2	2.60e-05	1313	53	13	int:USP7
Interaction	AFF1 interactions	CCNT1 TRIM25 AFF1 MLLT3	2.72e-05	66	53	4	int:AFF1
Interaction	YWHAZ interactions	TICRR BNIP5 YAF2 TRIM25 SH3RF1 MYCBP2 MAP6 KIF26B TRIP12 RGS12 GOLGA3 PSD4 EFTUD2	2.73e-05	1319	53	13	int:YWHAZ
Interaction	DDX23 interactions	TRIM25 SRSF4 SRSF6 PNN ZC3H13 PHRF1 AATF EFTUD2	3.38e-05	480	53	8	int:DDX23
Interaction	ELL3 interactions	CCNT1 AFF1 MLLT3	4.28e-05	26	53	3	int:ELL3
Interaction	ZNF689 interactions	ZBTB38 YAF2 SRSF4 SRSF6	4.28e-05	74	53	4	int:ZNF689
Interaction	SRSF6 interactions	SRSF4 SRSF6 PNN ZC3H13 PHRF1 WDR46 AATF EFTUD2	4.70e-05	503	53	8	int:SRSF6
Interaction	CDK13 interactions	TRIM25 SRSF4 SRSF6 WDR46 EFTUD2	5.05e-05	153	53	5	int:CDK13
Interaction	NR2C2 interactions	CCNT1 TRIM25 SRSF4 SH3RF1 SRSF6 PNN ZC3H13 WDR46 AATF RFC1 TRIP12 SREK1IP1 EFTUD2	5.19e-05	1403	53	13	int:NR2C2
Interaction	H1-2 interactions	YAF2 TRIM25 SETD1B SRSF6 ATRX PHRF1 AATF BSN EFTUD2	5.37e-05	666	53	9	int:H1-2
Interaction	XRCC5 interactions	ORC1 ZBTB38 YAF2 TRIM25 ATRX PHRF1 RFC1 EFTUD2	5.55e-05	515	53	8	int:XRCC5
Interaction	ELL interactions	CCNT1 TRIM25 AFF1 MLLT3	5.81e-05	80	53	4	int:ELL
Interaction	SFN interactions	CEP350 TRIM25 SRSF4 SH3RF1 MYCBP2 KIF26B RAB3IP TRIP12 RGS12	7.21e-05	692	53	9	int:SFN
Interaction	ASB8 interactions	HOXD4 MYCBP2 KIF26B	8.07e-05	32	53	3	int:ASB8
Interaction	SERINC5 interactions	TRIM25 MYCBP2 TRIP12	8.07e-05	32	53	3	int:SERINC5
Interaction	ELL2 interactions	CCNT1 AFF1 MLLT3	8.86e-05	33	53	3	int:ELL2
Interaction	NKTR interactions	TRIM25 SRSF4 SRSF6 PNN	9.21e-05	90	53	4	int:NKTR
Interaction	SRPK2 interactions	TRIM25 SRSF4 SRSF6 PNN MYCBP2 ZC3H13 AATF TRIP12 EFTUD2	9.46e-05	717	53	9	int:SRPK2
Interaction	MECP2 interactions	CCNT1 NRDE2 ZBTB38 SRSF4 SRSF6 ATRX PNN MYCBP2 MAP6 ZC3H13 TRIP12 EFTUD2	1.01e-04	1287	53	12	int:MECP2
Interaction	SNIP1 interactions	CCNT1 SRSF4 SRSF6 PNN PHRF1 AATF EFTUD2	1.05e-04	417	53	7	int:SNIP1
Interaction	ZMYND11 interactions	SRSF4 HOXD4 PNN EFTUD2	1.09e-04	94	53	4	int:ZMYND11
Interaction	YWHAH interactions	CEP350 TICRR YAF2 SH3RF1 PNN MYCBP2 KIF26B ZC3H13 TRIP12 RGS12 EFTUD2	1.14e-04	1102	53	11	int:YWHAH
Interaction	DHX8 interactions	TRIM25 SRSF4 SRSF6 PNN ZC3H13 PHRF1	1.14e-04	292	53	6	int:DHX8
Interaction	KCNE3 interactions	CEP350 ORC1 PNN TMEM131L MLLT3 TRIP12	1.23e-04	296	53	6	int:KCNE3
Interaction	EPB41L2 interactions	CCNT1 PNN TBCK MLLT3 TRIP12 EFTUD2	1.30e-04	299	53	6	int:EPB41L2
Interaction	BRIX1 interactions	TRIM25 SRSF4 SRSF6 WDR46 AATF EFTUD2	1.32e-04	300	53	6	int:BRIX1
Interaction	SAP18 interactions	SRSF6 PNN ZC3H13 PHRF1 USP37 EFTUD2	1.44e-04	305	53	6	int:SAP18
Interaction	MCM4 interactions	ORC1 ZBTB38 TRIM25 ATRX USP37 EFTUD2	1.47e-04	306	53	6	int:MCM4
Interaction	KMT2A interactions	CCNT1 SETD1B SRSF4 SRSF6 AFF1 MLLT3	1.69e-04	314	53	6	int:KMT2A
Interaction	BCLAF1 interactions	SRSF6 PNN MYCBP2 TBCK PHRF1 AATF	2.11e-04	327	53	6	int:BCLAF1
Interaction	CLK4 interactions	YAF2 SRSF4 SRSF6	2.11e-04	44	53	3	int:CLK4
Interaction	CSNK2B interactions	ORC1 YAF2 SRSF6 ATRX PHRF1 RFC1 SREK1IP1 EFTUD2	2.12e-04	625	53	8	int:CSNK2B
Interaction	IMP4 interactions	SRSF4 SRSF6 WDR46 AATF	2.22e-04	113	53	4	int:IMP4
Interaction	AFF4 interactions	CCNT1 TRIM25 AFF1 MLLT3	2.37e-04	115	53	4	int:AFF4
Interaction	SRPK1 interactions	ZBTB38 YAF2 TRIM25 SRSF4 SRSF6 PNN EFTUD2	2.39e-04	477	53	7	int:SRPK1
Interaction	SMC5 interactions	CCNT1 SRSF4 SRSF6 ATRX PNN ZC3H13 AATF RFC1 TRIP12 EFTUD2	2.41e-04	1000	53	10	int:SMC5
Interaction	SNRNP40 interactions	SRSF6 PNN ZC3H13 PHRF1 AATF RFC1 USP37 EFTUD2	2.41e-04	637	53	8	int:SNRNP40
Interaction	RPS19 interactions	CCNT1 YAF2 TRIM25 SRSF4 SRSF6 AATF BSN EFTUD2	2.46e-04	639	53	8	int:RPS19
Interaction	CCAR2 interactions	ZBTB38 AFF1 MLLT3 AATF USP37 EFTUD2	2.48e-04	337	53	6	int:CCAR2
Interaction	PIP4K2A interactions	CCNT1 SETD1B PNN AFF1 MLLT3	2.55e-04	216	53	5	int:PIP4K2A
Interaction	RBBP6 interactions	ZBTB38 SRSF4 SRSF6 PNN RGS12	2.55e-04	216	53	5	int:RBBP6
Interaction	ANKHD1 interactions	BNIP5 TRIM25 HOXD4 GOLGA3 EFTUD2	2.55e-04	216	53	5	int:ANKHD1
Interaction	CBX3 interactions	YAF2 ATRX ZC3H13 TBCK RFC1 USP37 TRIP12 EFTUD2	2.65e-04	646	53	8	int:CBX3
Interaction	YWHAB interactions	CEP350 TICRR YAF2 TRIM25 SH3RF1 MYCBP2 KIF26B TRIP12 RGS12 EFTUD2	2.69e-04	1014	53	10	int:YWHAB
Interaction	WRNIP1 interactions	ZBTB38 SRSF4 ATRX USP37	2.71e-04	119	53	4	int:WRNIP1
Interaction	RPS13 interactions	CCNT1 TRIM25 SRSF4 SRSF6 WDR46 AFF1 EFTUD2	2.78e-04	489	53	7	int:RPS13
Interaction	RBM19 interactions	TRIM25 SRSF4 SRSF6 AATF EFTUD2	2.83e-04	221	53	5	int:RBM19
Interaction	PAXBP1 interactions	SRSF4 SRSF6 USP37 EFTUD2	2.88e-04	121	53	4	int:PAXBP1
Interaction	RNU5A-1 interactions	TRIM25 EFTUD2	3.01e-04	10	53	2	int:RNU5A-1
Interaction	BMI1 interactions	YAF2 TRIM25 SRSF4 SRSF6 ATRX KIF26B ZC3H13 EFTUD2	3.03e-04	659	53	8	int:BMI1
Interaction	ZNF668 interactions	TRIM25 SRSF6 WDR46 AATF RFC1	3.14e-04	226	53	5	int:ZNF668
Interaction	DAXX interactions	SETD1B SRSF6 ATRX PNN MLLT3 RFC1	3.17e-04	353	53	6	int:DAXX
Interaction	PPIG interactions	ZBTB38 SRSF4 SRSF6 PNN	3.47e-04	127	53	4	int:PPIG
Interaction	SMOC1 interactions	TRIM25 PNN MLLT3	3.87e-04	54	53	3	int:SMOC1
Interaction	CDK9 interactions	CCNT1 SETD1B PNN ZC3H13 AFF1 MLLT3 TRIP12 EFTUD2	3.92e-04	685	53	8	int:CDK9
Interaction	KCNJ1 interactions	SH3RF1 GOLGA3	4.40e-04	12	53	2	int:KCNJ1
Interaction	AATF interactions	SRSF4 SRSF6 MYCBP2 PHRF1 WDR46 AATF	4.44e-04	376	53	6	int:AATF
Interaction	BCR interactions	NRDE2 TRIM25 ATRX PNN PSD4	4.46e-04	244	53	5	int:BCR
Interaction	SCAF1 interactions	SRSF4 SRSF6 PNN PHRF1	4.50e-04	136	53	4	int:SCAF1
Interaction	KRR1 interactions	SRSF4 SRSF6 WDR46 AATF TRIP12 EFTUD2	4.63e-04	379	53	6	int:KRR1
Interaction	IFI16 interactions	SRSF4 SRSF6 PNN WDR46 AATF RFC1 TRIP12 EFTUD2	5.16e-04	714	53	8	int:IFI16
Interaction	RNU4ATAC interactions	TRIM25 EFTUD2	5.20e-04	13	53	2	int:RNU4ATAC
Interaction	PHRF1 interactions	SRSF6 PHRF1 AATF	5.55e-04	61	53	3	int:PHRF1
Interaction	PPP6R3 interactions	ZBTB38 TRIM25 SRSF6 GOLGA3 EFTUD2	5.75e-04	258	53	5	int:PPP6R3
Interaction	CCNT2 interactions	CCNT1 TRIM25 MLLT3	5.82e-04	62	53	3	int:CCNT2
Interaction	RNU6ATAC interactions	TRIM25 EFTUD2	6.05e-04	14	53	2	int:RNU6ATAC
Interaction	MAGOH interactions	SRSF4 SRSF6 PNN ZC3H13 EFTUD2	6.38e-04	264	53	5	int:MAGOH
Interaction	PPP1CC interactions	PRR12 TRIM25 SRSF4 SRSF6 PNN MYCBP2 ZC3H13 EFTUD2	6.42e-04	738	53	8	int:PPP1CC
Interaction	TAF15 interactions	CCNT1 TRIM25 SRSF6 PNN MYCBP2 EFTUD2	6.82e-04	408	53	6	int:TAF15
Interaction	RN7SK interactions	CCNT1 TRIM25	6.97e-04	15	53	2	int:RN7SK
Interaction	HNRNPA1 interactions	CCNT1 YAF2 TRIM25 SRSF4 SRSF6 PNN ZC3H13 AATF EFTUD2	7.28e-04	945	53	9	int:HNRNPA1
Interaction	EPB41L3 interactions	CCNT1 ATRX PNN AFF1 MLLT3	7.30e-04	272	53	5	int:EPB41L3
Interaction	SF3A2 interactions	SRSF4 SH3RF1 SRSF6 PNN EFTUD2	7.42e-04	273	53	5	int:SF3A2
Interaction	SMC1A interactions	PRR12 SRSF6 ATRX RFC1 USP37 EFTUD2	7.74e-04	418	53	6	int:SMC1A
Interaction	ETV4 interactions	PRR12 TRIM25 HOXD4	7.96e-04	69	53	3	int:ETV4
Interaction	USP9X interactions	ZBTB38 TRIM25 SRSF4 SRSF6 PSD4 EFTUD2	8.13e-04	422	53	6	int:USP9X
Interaction	RSBN1 interactions	ZBTB38 SRSF6 PNN WDR46	8.47e-04	161	53	4	int:RSBN1
Interaction	PPIE interactions	CCDC74B SRSF4 SRSF6 PNN EFTUD2	8.58e-04	282	53	5	int:PPIE
Interaction	NOL10 interactions	TRIM25 SRSF6 WDR46 AATF	8.67e-04	162	53	4	int:NOL10
Interaction	MMACHC interactions	BNIP5 TRIM25	9.00e-04	17	53	2	int:MMACHC
Interaction	MCM6 interactions	ORC1 ATRX MLLT3 USP37 EFTUD2	9.28e-04	287	53	5	int:MCM6
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF1 MLLT3	1.02e-04	9	31	2	1280
GeneFamily	RNA binding motif containing\|Serine and arginine rich splicing factors	SRSF4 SRSF6	1.86e-04	12	31	2	737
GeneFamily	AAA ATPases	ORC1 RFC1	3.71e-03	53	31	2	413
GeneFamily	RNA binding motif containing	SETD1B SRSF4 SRSF6	5.68e-03	213	31	3	725
GeneFamily	Ring finger proteins	TRIM25 SH3RF1 PHRF1	1.14e-02	275	31	3	58
Coexpression	GSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_UP	TRABD2A PNN ZC3H13 MLLT3 USP37 CXorf65	2.48e-06	196	52	6	M8687
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	CEP350 NRDE2 ATRX PNN ZC3H13 WDR46	1.26e-07	197	53	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ZBTB38 ATRX PNN GOLGA3	2.13e-06	176	53	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	CCNT1 PNN MYCBP2 TBCK TMEM131L	3.18e-06	191	53	5	9454f642c3621370fa23640b631301346b300950
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB2 ZBTB38 ATRX MYCBP2 USP37	3.52e-06	195	53	5	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CEP350 ATRX PNN MYCBP2 TRIP12	3.98e-06	200	53	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	TRIM25 TBCK P2RY14 ZNF415	5.83e-05	177	53	4	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGFB2 MLLT3 P2RY14 RFC1	6.09e-05	179	53	4	ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	CCNT1 PNN MYCBP2 TMEM131L	6.92e-05	185	53	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B MAP6 CCDC74A TNNI3	6.92e-05	185	53	4	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	CCNT1 PNN MYCBP2 TMEM131L	7.07e-05	186	53	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CEP350 ATRX ZC3H13 USP37	7.07e-05	186	53	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB2 MAP6 KIF26B RAB3IP	7.68e-05	190	53	4	8a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	CEP350 ATRX AFF1 USP37	8.15e-05	193	53	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	TRABD2A ATRX PNN MLLT3	8.49e-05	195	53	4	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CEP350 ATRX MYCBP2 ZC3H13	9.00e-05	198	53	4	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	ZBTB38 ATRX MAP6 UNC13C	9.18e-05	199	53	4	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	CEP350 ATRX ZC3H13 RFC1	9.18e-05	199	53	4	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Neuron\|World / Primary Cells by Cluster	ZBTB38 ATRX MAP6 MLLT3	9.18e-05	199	53	4	1f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCell	Neuron-Postmitotic\|World / Primary Cells by Cluster	ZBTB38 ATRX MAP6 MLLT3	9.18e-05	199	53	4	1973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	ZBTB38 ATRX MAP6 UNC13C	9.18e-05	199	53	4	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	CEP350 ATRX ZC3H13 TRIP12	9.18e-05	199	53	4	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	ATRX PNN ZC3H13 RFC1	9.18e-05	199	53	4	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
Computational	Neighborhood of RAP1A	CEP350 YAF2 HOXD4 ATRX RFC1 SH2B1	7.31e-06	140	37	6	MORF_RAP1A
Computational	Neighborhood of ATRX	CEP350 YAF2 HOXD4 ATRX GOLGA3 SH2B1	8.27e-05	215	37	6	MORF_ATRX
Computational	Neighborhood of RFC1	ORC1 RFC1 SH2B1 PSD4	5.11e-04	109	37	4	MORF_RFC1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	CEP350 ZBTB38 ATRX	6.20e-04	49	37	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Computational	Neighborhood of IKBKG	ORC1 SETD1B SH2B1 PSD4	1.20e-03	137	37	4	MORF_IKBKG
Computational	Neighborhood of DDX5	SRSF4 PNN AFF1	1.42e-03	65	37	3	GCM_DDX5
Computational	Neighborhood of MT4	CEP350 HOXD4 ATRX RFC1 SH2B1	1.47e-03	247	37	5	MORF_MT4
Computational	Neighborhood of ORC1L	ORC1 RFC1 PSD4	1.68e-03	69	37	3	MORF_ORC1L
Disease	hematocrit	PRR12 ZBTB38 TRIM25 SRSF4 AFF1 MLLT3 BSN USP37 PSD4	3.16e-05	1011	48	9	EFO_0004348
Disease	body surface area	TGFB2 TICRR ZBTB38 OTOL1 TRIP12 ADCY9 PSD4	7.66e-05	643	48	7	EFO_0022196
Disease	cognitive function measurement, self reported educational attainment	PRR12 MYCBP2 BSN SREK1IP1 SH2B1	2.74e-04	355	48	5	EFO_0004784, EFO_0008354
Disease	mean reticulocyte volume	CEP350 TMEM131L AFF1 MLLT3 RFC1 SH2B1 ADCY9	2.91e-04	799	48	7	EFO_0010701
Disease	waist circumference	ZBTB38 MLLT3 UNC13C SH2B1 ADCY9	6.50e-04	429	48	5	EFO_0004342
Disease	colon adenocarcinoma (is_marker_for)	SRSF4 SRSF6	7.59e-04	25	48	2	DOID:234 (is_marker_for)
Disease	necrotizing enterocolitis	SRSF6 OTOL1	8.86e-04	27	48	2	EFO_0003928
Disease	body weight	TGFB2 ZBTB38 SH3RF1 MLLT3 OTOL1 TRIP12 SH2B1 ADCY9	8.95e-04	1261	48	8	EFO_0004338
Disease	clear cell renal cell carcinoma (is_marker_for)	SRSF4 SRSF6	1.32e-03	33	48	2	DOID:4467 (is_marker_for)
Disease	daytime rest measurement	SH3RF1 SRSF6 MYCBP2 KIF26B	1.35e-03	295	48	4	EFO_0007828
Disease	spondylosis	UNC13C PSD4	1.94e-03	40	48	2	MONDO_0002253
Disease	Congenital small ears	ORC1 EFTUD2	2.04e-03	41	48	2	C0152423
Disease	grip strength measurement	ZBTB38 TRIP12 SH2B1 ADCY9	2.51e-03	350	48	4	EFO_0006941
Disease	Heart Diseases	BSN TNNI3	2.56e-03	46	48	2	C0018799
Disease	sleep duration	PRR12 SH3RF1 MYCBP2 TBCK	2.83e-03	362	48	4	EFO_0005271

Protein segments in the cluster

Peptide	Gene	Start	Entry
RKHFKKFALSSPSKS	nan	251	A8MVM7
SGRSDKKKSTRKSPT	CXorf65	146	A6NEN9
PKRSSKSSCSKKLSK	CXorf66	161	Q5JRM2
PSRDHNKSSKESSKK	MLLT3	221	P42568
DHPAKIAKSTKSSSL	CCNT1	586	O60563
ATHFPKVSTKSLSKK	CCDC74A	321	Q96AQ1
ATHFPKVSTKSLSKK	CCDC74B	321	Q96LY2
KTPFKKGHTRNKSTS	RAB3IP	276	Q96QF0
SSKPKKTSASHKPTR	MAP6	381	Q96JE9
KTSASHKPTRKAKDK	MAP6	386	Q96JE9
LSSKKKKHRPSTSSA	KIF26B	396	Q2KJY2
SVKHPTNKRTSKSSL	KIAA1109	1516	Q2LD37
KSLAPAAISSKRSKH	BSN	3346	Q9UPA5
LTVHPESKSKTKTRS	PNN	546	Q9H307
KKTKRKHGPSSSSRS	NRDE2	96	Q9H7Z3
GPSAKSKSSATRSKK	PHRF1	356	Q9P1Y6
HPREKKTSKSSKIRS	GOLGA3	231	Q08378
KDHKLPNTKGRSSSS	HOXD4	211	P09016
SLKSSLHTLTKVPKK	ORC1	446	Q13415
SKSSGSSRSKRKPSI	ATRX	71	P46100
TSLKRTSKTNPKKHG	BNIP5	291	P0C671
PISKSTKSRKEKSRS	CEP350	91	Q5VT06
HATSSPKNRKKKSSI	ADCY9	361	O60503
TIAKTTPHTKFTKKS	OTOL1	21	A6NHN0
STTSSKPKLKKRFSL	SH2B1	141	Q9NRF2
PKSRSPSRHKSKSKS	SRSF4	286	Q08170
TKPSSEKKIHKTSRE	TMEM131L	1161	A2VDJ0
SKKSRPTSKRDSLAK	RFC1	526	P35251
SRAFSSAPLKKTKSS	FAM120AOS	161	Q5T036
GTREPKLSLKKSHSS	PSD4	1006	Q8NDX1
YHPSTSLSSAKKKKR	SETD1B	1721	Q9UPS6
KSELSSKHSRSLKPD	MYCBP2	2731	O75592
KSKSKPKSDRGSHSH	SRSF6	246	Q13247
STKPKKLLKTSSFHL	PRR12	1066	Q9ULL5
KKIFKSHLKSSRNST	P2RY14	211	Q15391
KKRKKEKHSSTPNSS	SREK1IP1	136	Q8N9Q2
SSTAPKHSDTKKNTK	SH3RF1	286	Q7Z6J0
SKKSRSHSAKTPGFS	AATF	136	Q9NY61
SSSHKESSKTKPSRP	AFF1	841	P51825
TIKSTRKKNSGKTPH	TGFB2	266	P61812
PKKSHQKSLSFSKTT	TICRR	1106	Q7Z2Z1
SKSKDKKSPLHFAAS	TRPA1	441	O75762
HSSVSTPKKLSGKSK	RGS12	861	O14924
KGSTSKPSSKSHSAR	UNC13C	476	Q8NB66
KPSSKSHSARSKNKT	UNC13C	481	Q8NB66
ASTHKSTRPVKKVSK	TRIM25	371	Q14258
TTSKKNSHKKTRPRL	YAF2	91	Q8IY57
KGKSKKTSTRPTLST	TRABD2A	361	Q86V40
VTGHFKTPSKKTKSS	TBCK	776	Q8TEA7
DKSRKLPHSKAKTRS	WDR46	116	O15213
TEPHAKKKSKISASR	TNNI3	31	P19429
TPSKKFTFKSKSSLA	USP37	631	Q86T82
ALDHRKPSTSSKKTK	ZNF415	36	Q09FC8
PKSIKEKKKTTSHTR	ZBTB38	771	Q8NAP3
PKTRKFTKKAPTSSS	EFTUD2	351	Q15029
RSAKPTKLASKSATS	TRIP12	171	Q14669
SKSPKRKSSPKSSSA	ZC3H13	216	Q5T200
RKSSPKSSSASKKDR	ZC3H13	221	Q5T200