Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL28A1

1.83e-1346277GO:0030020
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL28A1

4.44e-09188277GO:0005201
GeneOntologyMolecularFunctionstructural molecule activity

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL28A1 PCLO

1.59e-05891278GO:0005198
GeneOntologyMolecularFunctionvoltage-gated chloride channel activity

CLCNKA CLCNKB

9.61e-0511272GO:0005247
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

CLCNKA CLCNKB

2.36e-0417272GO:0008308
GeneOntologyMolecularFunctiontranscription coactivator activity

BCL9L KMT2D EP300 SS18L1

6.93e-04303274GO:0003713
GeneOntologyMolecularFunctionmolecular adaptor activity

COL4A4 BCL9L KMT2D COL11A2 WNK1 EP300 SS18L1

1.74e-031356277GO:0060090
GeneOntologyMolecularFunctionheparin binding

COL11A2 COL25A1 COL28A1

2.16e-03192273GO:0008201
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

BCL9L KMT2D COL11A2 WNK1 EP300 SS18L1

3.91e-031160276GO:0030674
GeneOntologyMolecularFunctionglycosaminoglycan binding

COL11A2 COL25A1 COL28A1

5.51e-03268273GO:0005539
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

CHD7 EP300

5.60e-0383272GO:1990841
GeneOntologyMolecularFunctionchloride channel activity

CLCNKA CLCNKB

6.00e-0386272GO:0005254
GeneOntologyMolecularFunctiontranscription coregulator activity

BCL9L KMT2D EP300 SS18L1

6.51e-03562274GO:0003712
GeneOntologyBiologicalProcessmRNA 3'-end processing

PCF11 WDR33 CSTF2T

2.92e-0546273GO:0031124
GeneOntologyBiologicalProcesstransepithelial chloride transport

CLCNKA CLCNKB

7.38e-0510272GO:0030321
GeneOntologyBiologicalProcessglomerular basement membrane development

COL4A3 COL4A4

7.38e-0510272GO:0032836
GeneOntologyBiologicalProcesscollagen-activated tyrosine kinase receptor signaling pathway

COL4A1 COL4A3

1.08e-0412272GO:0038063
GeneOntologyBiologicalProcessextracellular matrix organization

COL4A1 COL4A3 COL4A4 COL11A2 COL28A1

1.15e-04377275GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

COL4A1 COL4A3 COL4A4 COL11A2 COL28A1

1.17e-04378275GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

COL4A1 COL4A3 COL4A4 COL11A2 COL28A1

1.18e-04379275GO:0045229
GeneOntologyBiologicalProcesstermination of RNA polymerase II transcription

PCF11 WNK1

1.96e-0416272GO:0006369
GeneOntologyBiologicalProcesscollagen-activated signaling pathway

COL4A1 COL4A3

2.49e-0418272GO:0038065
GeneOntologyBiologicalProcessRNA 3'-end processing

PCF11 WDR33 CSTF2T

2.80e-0498273GO:0031123
GeneOntologyCellularComponentcollagen trimer

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 SFTPD COL20A1 WDR33 COL28A1

1.27e-17882810GO:0005581
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A1 COL4A3 COL4A4 COL11A2 COL28A1

5.93e-1121285GO:0098644
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 SFTPD COL20A1 COL28A1

1.82e-08530289GO:0062023
GeneOntologyCellularComponentcollagen type IV trimer

COL4A1 COL4A3 COL4A4

4.29e-086283GO:0005587
GeneOntologyCellularComponentextracellular matrix

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 SFTPD COL20A1 COL28A1

1.13e-07656289GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 SFTPD COL20A1 COL28A1

1.16e-07658289GO:0030312
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A1 COL4A3 COL4A4

1.20e-078283GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A1 COL4A3 COL4A4

1.20e-078283GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A1 COL4A3 COL4A4

1.20e-078283GO:0098645
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL4A1 COL4A3 COL4A4 COL11A2 COL25A1 COL20A1 COL28A1

2.13e-07332287GO:0005788
GeneOntologyCellularComponentmRNA cleavage factor complex

PCF11 WDR33 CSTF2T

9.43e-0631283GO:0005849
GeneOntologyCellularComponentbasement membrane

COL4A1 COL4A3 COL4A4 COL28A1

2.03e-05122284GO:0005604
GeneOntologyCellularComponentfibrillar collagen trimer

COL11A2 COL28A1

1.13e-0412282GO:0005583
GeneOntologyCellularComponentbanded collagen fibril

COL11A2 COL28A1

1.13e-0412282GO:0098643
GeneOntologyCellularComponentmRNA cleavage and polyadenylation specificity factor complex

WDR33 CSTF2T

5.51e-0426282GO:0005847
GeneOntologyCellularComponentchloride channel complex

CLCNKA CLCNKB

2.64e-0357282GO:0034707
HumanPhenoGlomerular basement membrane lamellation

COL4A3 COL4A4

2.77e-053162HP:0030034
HumanPhenoThin glomerular basement membrane

COL4A3 COL4A4

2.77e-053162HP:0012577
HumanPhenoHypokalemic hypochloremic metabolic alkalosis

CLCNKA CLCNKB

2.77e-053162HP:0004909
HumanPhenoHypochloremic metabolic alkalosis

CLCNKA CLCNKB

5.53e-054162HP:0005977
HumanPhenoAbnormal urine chloride concentration

CLCNKA CLCNKB

9.20e-055162HP:0012600
HumanPhenoHyperchloriduria

CLCNKA CLCNKB

9.20e-055162HP:0002914
HumanPhenoAbnormal circulating renin concentration

CLCNKA CLCNKB WNK1

1.31e-0433163HP:0040084
HumanPhenoAbnormal circulating prostaglandin circulation

CLCNKA CLCNKB

1.38e-046162HP:0011023
HumanPhenoHyperprostaglandinuria

CLCNKA CLCNKB

1.38e-046162HP:0003527
HumanPhenoImpaired renal concentrating ability

CLCNKA CLCNKB

1.92e-047162HP:0004727
HumanPhenoHypochloremia

CLCNKA CLCNKB

1.92e-047162HP:0003113
HumanPhenoAbnormal blood chloride concentration

CLCNKA CLCNKB WNK1

2.17e-0439163HP:0011422
HumanPhenoMixed hearing impairment

CHD7 KMT2D COL11A2

2.34e-0440163HP:0000410
HumanPhenoPolyhydramnios

CHD7 KMT2D COL11A2 CLCNKA CLCNKB EP300

2.39e-04312166HP:0001561
HumanPhenoAbnormal circulating unsaturated fatty acid concentration

CLCNKA CLCNKB

2.56e-048162HP:0011022
HumanPhenoHyperactive renin-angiotensin system

CLCNKA CLCNKB

2.56e-048162HP:0000841
HumanPhenoAbnormal circulating eicosanoid concentration

CLCNKA CLCNKB

2.56e-048162HP:0030361
HumanPhenoHypokalemic metabolic alkalosis

CLCNKA CLCNKB

3.29e-049162HP:0001960
HumanPhenoIncreased urinary potassium

CLCNKA CLCNKB

3.29e-049162HP:0003081
HumanPhenoImpaired renal function

CLCNKA CLCNKB

3.29e-049162HP:0000087
HumanPhenoPilomatrixoma

KMT2D EP300

3.29e-049162HP:0030434
HumanPhenoLenticonus

COL4A3 COL4A4

4.10e-0410162HP:0001142
HumanPhenoHypernatriuria

CLCNKA CLCNKB

4.10e-0410162HP:0012605
HumanPhenoAbnormality of the amniotic fluid

CHD7 KMT2D COL11A2 COL25A1 CLCNKA CLCNKB EP300

4.60e-04504167HP:0001560
HumanPhenoAbnormality of renal physiology

COL4A1 COL4A3 COL4A4 CHD7 KMT2D CLCNKA CLCNKB EP300

5.18e-04691168HP:0000082
HumanPhenoHypokalemic alkalosis

CLCNKA CLCNKB

5.99e-0412162HP:0001949
HumanPhenoFetal polyuria

CLCNKA CLCNKB

5.99e-0412162HP:0001563
HumanPhenoThickened glomerular basement membrane

COL4A3 COL4A4

5.99e-0412162HP:0004722
HumanPhenoAbnormality of renin-angiotensin system

CLCNKA CLCNKB WNK1

6.04e-0455163HP:0000847
HumanPhenoStage 5 chronic kidney disease

COL4A3 COL4A4 CLCNKA CLCNKB

6.70e-04135164HP:0003774
HumanPhenoMarcus Gunn jaw winking synkinesis

KMT2D COL25A1

7.07e-0413162HP:0025186
HumanPhenoAbnormal glomerular basement membrane morphology

COL4A3 COL4A4

7.07e-0413162HP:0033282
MousePhenoabnormal urination

COL4A1 COL4A3 COL4A4 CLCNKA CLCNKB WNK1

1.91e-07148256MP:0001756
MousePhenopolyuria

COL4A1 COL4A3 COL4A4 CLCNKA CLCNKB

4.49e-0789255MP:0001762
MousePhenosensorineural hearing impairment

COL4A3 COL4A4 CHD7 COL11A2

5.64e-0738254MP:0006329
MousePhenohematuria

COL4A1 COL4A3 COL4A4

4.80e-0619253MP:0005161
MousePhenorenal cast

COL4A1 COL4A3 COL4A4

2.91e-0534253MP:0011402
MousePhenosensorineural hearing loss

COL4A3 COL4A4 COL11A2

3.77e-0537253MP:0004740
MousePhenopodocyte foot process effacement

COL4A1 COL4A3 COL4A4

4.09e-0538253MP:0008140
MousePhenoabnormal renal glomerulus basement membrane morphology

COL4A1 COL4A3 COL4A4

6.38e-0544253MP:0011348
MousePhenoabnormal blood circulation

COL4A1 COL4A3 CHD7 COL11A2 CLCNKB WNK1 EP300 SEC23A

7.41e-05845258MP:0002128
MousePhenoabnormal urine sodium level

COL4A4 CLCNKB WNK1

9.94e-0551253MP:0006274
MousePhenodecreased urine osmolality

COL4A1 CLCNKA CLCNKB

1.18e-0454253MP:0002988
MousePhenoabnormal renal filtration

COL4A3 COL4A4 CLCNKB

1.18e-0454253MP:0013285
MousePhenoabnormal podocyte foot process morphology

COL4A1 COL4A3 COL4A4

1.25e-0455253MP:0008059
MousePhenoabnormal urine homeostasis

COL4A1 COL4A3 COL4A4 CLCNKA CLCNKB WNK1

1.37e-04466256MP:0009643
MousePhenoincreased blood urea nitrogen level

COL4A1 COL4A3 COL4A4 CHD7 CLCNKB

1.38e-04289255MP:0005565
MousePhenoembryonic lethality during organogenesis, complete penetrance

BCL9L FGD5 CHD7 KMT2D WNK1 EP300 SEC23A

1.67e-04700257MP:0011098
MousePhenoalbuminuria

COL4A1 COL4A3 COL4A4

1.87e-0463253MP:0002871
MousePhenoabnormal urine osmolality

COL4A1 CLCNKA CLCNKB

2.05e-0465253MP:0002987
MousePhenoabnormal podocyte morphology

COL4A1 COL4A3 COL4A4

2.56e-0470253MP:0005326
MousePhenoabnormal glomerular capsule visceral layer morphology

COL4A1 COL4A3 COL4A4

2.56e-0470253MP:0011497
MousePhenoabnormal kidney vasculature morphology

COL4A1 COL4A3 CLCNKB

2.89e-0473253MP:0000530
MousePhenodecreased renal glomerular filtration rate

COL4A3 CLCNKB

3.18e-0415252MP:0005528
MousePhenoabnormal collagen level

COL4A1 SEC23A

3.63e-0416252MP:0020252
MousePhenoabnormal glomerular mesangium morphology

COL4A1 COL4A3 COL4A4

4.22e-0483253MP:0011339
MousePhenoabnormal pupil morphology

COL4A1 COL4A3 CHD7

4.53e-0485253MP:0001317
MousePhenothin myocardium

CHD7 WNK1 EP300

4.53e-0485253MP:0002652
MousePhenoglomerular crescent

COL4A3 COL4A4

5.15e-0419252MP:0011506
MousePhenointernal hemorrhage

COL4A1 COL4A3 WNK1 EP300 SEC23A

5.33e-04387255MP:0001634
MousePhenoabnormal blood urea nitrogen level

COL4A1 COL4A3 COL4A4 CHD7 CLCNKB

5.46e-04389255MP:0005265
MousePhenoimpaired hearing

COL4A3 COL4A4 CHD7 COL11A2

6.13e-04223254MP:0006325
MousePhenoabnormal face shape

CHD7 COL11A2

6.32e-0421252MP:0030071
MousePhenoabnormal renal tubule morphology

COL4A1 COL4A3 COL4A4 CLCNKB

6.55e-04227254MP:0002703
MousePhenoembryonic lethality during organogenesis

BCL9L FGD5 CHD7 KMT2D WNK1 EP300 SEC23A

6.57e-04876257MP:0006207
MousePhenodilated renal tubule

COL4A1 COL4A4 CLCNKB

7.50e-04101253MP:0002705
MousePhenoincreased or absent threshold for auditory brainstem response

COL4A3 COL4A4 CHD7 COL11A2

7.58e-04236254MP:0011967
MousePhenointracranial hemorrhage

COL4A1 WNK1 SEC23A

8.17e-04104253MP:0001915
MousePhenoabnormal renal glomerular capsule morphology

COL4A1 COL4A3 COL4A4

8.87e-04107253MP:0002828
MousePhenoabnormal renal glomerular filtration rate

COL4A3 CLCNKB

8.98e-0425252MP:0002847
MousePhenohemorrhage

COL4A1 COL4A3 CHD7 WNK1 EP300 SEC23A

9.16e-04664256MP:0001914
MousePhenouremia

COL4A1 COL4A3 COL4A4 CHD7 CLCNKB

9.24e-04437255MP:0009644
MousePhenoincreased renal glomerulus basement membrane thickness

COL4A3 COL4A4

1.05e-0327252MP:0011409
MousePhenoabnormal renal/urinary system physiology

COL4A1 COL4A3 COL4A4 CLCNKA CLCNKB WNK1

1.16e-03695256MP:0005502
MousePhenoabnormal renal glomerular filtration

COL4A3 CLCNKB

1.21e-0329252MP:0013284
MousePhenodecreased urine sodium level

COL4A4 WNK1

1.21e-0329252MP:0006317
MousePhenorenal tubule atrophy

COL4A3 COL4A4

1.30e-0330252MP:0011346
MousePhenoabnormal renal glomerulus basement membrane thickness

COL4A3 COL4A4

1.38e-0331252MP:0011349
MousePhenopale kidney

COL4A3 COL4A4

1.57e-0333252MP:0004969
MousePhenoabnormal renal corpuscle morphology

COL4A1 COL4A3 COL4A4 CLCNKB

1.69e-03293254MP:0002827
MousePhenoabnormal urine potassium level

COL4A4 CLCNKB

1.86e-0336252MP:0004820
MousePhenoabnormal inner ear morphology

COL4A3 CHD7 KMT2D COL11A2

1.91e-03303254MP:0000026
MousePhenopremature death

COL4A1 COL4A3 COL4A4 CHD7 CLCNKB PCLO SS18L1

1.92e-031051257MP:0002083
MousePhenoirregularly shaped pupil

COL4A1 COL4A3

2.18e-0339252MP:0001319
MousePhenoabnormal basement membrane morphology

COL4A1 COL4A3

2.30e-0340252MP:0004272
MousePhenoincreased urine protein level

COL4A1 COL4A3 COL4A4

2.30e-03149253MP:0002962
MousePhenoabnormal red blood cell distribution width

FGD5 CHD7 CLCNKB EP300

2.30e-03319254MP:0010066
MousePhenoabnormal kidney cortex morphology

COL4A1 COL4A3 COL4A4 CLCNKB

2.44e-03324254MP:0000521
DomainCollagen

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 SFTPD COL20A1 WDR33 COL28A1

2.71e-17852810PF01391
DomainCollagen

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 SFTPD COL20A1 WDR33 COL28A1

2.71e-17852810IPR008160
DomainC4

COL4A1 COL4A3 COL4A4

6.02e-086283SM00111
Domain-

COL4A1 COL4A3 COL4A4

6.02e-0862832.170.240.10
DomainCollagen_VI_NC

COL4A1 COL4A3 COL4A4

6.02e-086283IPR001442
DomainNC1_IV

COL4A1 COL4A3 COL4A4

6.02e-086283PS51403
DomainC4

COL4A1 COL4A3 COL4A4

6.02e-086283PF01413
DomainCl_channel-K

CLCNKA CLCNKB

2.17e-062282IPR002250
Domain-

COL6A5 COL20A1 COL28A1 SEC23A

4.33e-06742843.40.50.410
DomainVWF_A

COL6A5 COL20A1 COL28A1 SEC23A

1.38e-0599284IPR002035
DomainCTDL_fold

COL4A1 COL4A3 COL4A4 SFTPD

1.88e-05107284IPR016187
DomainCl-channel_core

CLCNKA CLCNKB

7.75e-059282IPR014743
Domain-

CLCNKA CLCNKB

7.75e-0592821.10.3080.10
DomainVoltage_CLC

CLCNKA CLCNKB

7.75e-059282PF00654
DomainCl-channel_volt-gated

CLCNKA CLCNKB

7.75e-059282IPR001807
DomainVWA

COL6A5 COL20A1 COL28A1

7.93e-0556283PF00092
DomainVWFA

COL6A5 COL20A1 COL28A1

2.47e-0482283PS50234
DomainCBS

CLCNKA CLCNKB

2.57e-0416282SM00116
DomainVWA

COL6A5 COL20A1 COL28A1

2.65e-0484283SM00327
DomainCBS_dom

CLCNKA CLCNKB

4.05e-0420282IPR000644
DomainCBS

CLCNKA CLCNKB

4.05e-0420282PF00571
DomainCBS

CLCNKA CLCNKB

4.05e-0420282PS51371
DomainTSPN

COL11A2 COL20A1

5.38e-0423282SM00210
DomainZnf_FYVE_PHD

FGD5 KMT2D PCLO

1.35e-03147283IPR011011
DomainLaminin_G

COL11A2 COL20A1

3.40e-0358282IPR001791
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

3.72e-1541268MM15538
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

6.88e-1544268M27812
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

1.12e-1361268MM14637
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

2.47e-1367268M26999
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

7.06e-1376268MM14573
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

2.86e-1290268M631
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1

4.58e-1053266MM14566
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1

1.48e-0964266M26953
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

1.33e-08258268MM14572
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2

2.84e-0850265MM14796
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

4.29e-08300268M610
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A3 COL4A4 COL6A5

4.32e-0820264MM15061
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1

4.94e-08114266MM14571
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2

7.87e-0861265M27103
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1

1.68e-07140266M587
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A1 COL4A3 COL4A4 COL11A2

3.16e-0732264MM14924
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A1 COL4A3 COL4A4 COL6A5

6.43e-0738264MM14969
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A3 COL4A4

6.63e-0710263M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A3 COL4A4

6.63e-0710263MM1560
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A3 COL4A4

9.10e-0711263M15422
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A3 COL4A4 COL6A5

9.70e-0742264M7169
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A3 COL4A4

1.21e-0612263MM1526
PathwayPID_SYNDECAN_1_PATHWAY

COL4A1 COL4A3 COL4A4 COL11A2

1.41e-0646264M198
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A3 COL4A4

1.57e-0613263MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A3 COL4A4

1.57e-0613263M12950
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A3 COL4A4

2.00e-0614263MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A3 COL4A4

2.00e-0614263M6487
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A3 COL4A4

2.50e-0615263MM14922
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A1 COL4A3 COL4A4

2.50e-0615263M27161
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A3 COL4A4 COL6A5

3.36e-0657264MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A3 COL4A4 COL6A5

3.60e-0658264M2049
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A1 COL4A3 COL4A4 COL11A2

3.86e-0659264M27218
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A3 COL4A4

4.46e-0618263M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A3 COL4A4

4.46e-0618263MM14882
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A1 COL4A3 COL4A4 COL6A5

5.03e-0663264M11187
PathwayPID_INTEGRIN1_PATHWAY

COL4A1 COL4A3 COL4A4 COL11A2

6.06e-0666264M18
PathwayREACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS

PCF11 WDR33 CSTF2T

6.22e-0620263M497
PathwayBIOCARTA_AMI_PATHWAY

COL4A1 COL4A3 COL4A4

6.22e-0620263M15394
PathwayREACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS

PCF11 WDR33 CSTF2T

6.22e-0620263MM15469
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL4A1 COL4A3 COL4A4 COL11A2

9.58e-0674264M160
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A3 COL4A4

9.63e-0623263M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A3 COL4A4

9.63e-0623263MM1427
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A1 COL4A3 COL4A4 COL6A5

1.07e-0576264M27219
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A1 COL4A3 COL4A4 COL6A5

1.07e-0576264MM14867
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L KMT2D EP300

1.41e-0526263MM14793
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A1 COL4A3 COL4A4 COL6A5

1.66e-0585264M16441
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA

PCF11 WDR33 CSTF2T

1.97e-0529263M783
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA

PCF11 WDR33 CSTF2T

1.97e-0529263MM15444
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A3 COL4A4

2.19e-0530263M27216
PathwayPID_INTEGRIN3_PATHWAY

COL4A1 COL4A3 COL4A4

6.55e-0543263M53
PathwayWP_DISTAL_CONVOLUTED_TUBULE_1_DCT1_CELL

CLCNKB WNK1

6.83e-057262MM15929
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 EP300

9.12e-05418266MM15587
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION

PCF11 WDR33 CSTF2T

1.96e-0462263MM15426
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION

PCF11 WDR33 CSTF2T

2.47e-0467263M27694
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 EP300

3.39e-04532266M27870
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL4A1 COL4A4 COL11A2

4.81e-0484263M7098
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L KMT2D EP300

6.08e-0491263M27101
PathwayWP_SMALL_CELL_LUNG_CANCER

COL4A1 COL4A3 COL4A4

7.10e-0496263M39834
PathwayREACTOME_STIMULI_SENSING_CHANNELS

CLCNKA CLCNKB WNK1

9.47e-04106263M27200
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

COL4A1 COL4A3 COL4A4 COL6A5

1.25e-03261264MM15676
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

BCL9L KMT2D

2.69e-0342262M27272
PathwayPID_HNF3A_PATHWAY

SFTPD EP300

2.95e-0344262M285
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

KMT2D EP300

2.95e-0344262MM15527
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

BCL9L KMT2D EP300

2.97e-03158263MM14791
PathwayWP_NEPHROTIC_SYNDROME

COL4A3 COL4A4

3.08e-0345262M39864
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

COL4A1 COL4A3 COL4A4

3.13e-03161263M39770
PathwayWP_PI3KAKT_SIGNALING

COL4A1 COL4A3 COL4A4 COL6A5

3.23e-03339264M39736
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CLCNKA CLCNKB WNK1

4.49e-03183263M997
PathwayWP_FOCAL_ADHESION

COL4A1 COL4A4 COL11A2

4.77e-03187263MM15913
PathwayKEGG_FOCAL_ADHESION

COL4A1 COL4A4 COL11A2

5.67e-03199263M7253
PathwayPID_RB_1PATHWAY

SFTPD EP300

6.34e-0365262M279
Pubmed

Nature and the multiple functions of the 67-kD elastin-/laminin binding protein.

COL4A1 COL4A3 COL4A4

2.08e-0942937827955
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

COL4A1 COL4A4 COL6A5 COL25A1 SFTPD COL28A1

4.85e-0916729622159717
Pubmed

In vitro interactions of oxidatively modified LDL with type I, II, III, IV, and V collagen, laminin, fibronectin, and poly-D-lysine.

COL4A1 COL4A3 COL4A4

5.21e-0952939409248
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL28A1

6.43e-0917529628071719
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A1 COL4A3 COL4A4

1.04e-08629310534397
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A1 COL4A3 COL4A4

1.04e-0862939506531
Pubmed

HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.

COL4A1 COL4A3 COL4A4

1.04e-0862937495302
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A1 COL4A3 COL4A4

1.04e-0862939673377
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A1 COL4A3 COL4A4

1.04e-0862932426947
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A1 COL4A3 COL4A4

1.04e-08629323551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A1 COL4A3 COL4A4

1.04e-0862936811420
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A1 COL4A3 COL4A4

1.04e-08629311732842
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A1 COL4A3 COL4A4

1.04e-08629319275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A1 COL4A3 COL4A4

1.04e-0862936988303
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A1 COL4A3 COL4A4

1.04e-0862936389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A1 COL4A3 COL4A4

1.04e-08629312225806
Pubmed

Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.

COL4A1 COL4A3 COL4A4

1.82e-08729310639489
Pubmed

Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.

COL4A1 COL4A3 COL4A4

1.82e-0872937521231
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A1 COL4A3 COL4A4

1.82e-08729311711546
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A1 COL4A3 COL4A4

1.82e-0872938006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A1 COL4A3 COL4A4

1.82e-08729310416788
Pubmed

Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).

COL4A1 COL4A3 COL4A4

1.82e-08729310716744
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A1 COL4A3 COL4A4

1.82e-0872931724753
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL4A1 COL4A3 COL4A4

2.91e-08829310382266
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL4A1 COL4A3 COL4A4

2.91e-0882933997552
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A1 COL4A3 COL4A4

2.91e-08829329422532
Pubmed

Mice develop normally without tenascin.

COL4A1 COL4A3 COL4A4

2.91e-0882931383086
Pubmed

Molecular properties of wild-type and mutant betaIG-H3 proteins.

COL4A1 COL4A3 COL4A4

2.91e-08829311867580
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A1 COL4A3 COL4A4

4.36e-0892939878537
Pubmed

Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.

COL4A1 COL4A3 COL4A4

4.36e-0892938562707
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A1 COL4A3 COL4A4

4.36e-08929312101409
Pubmed

Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.

COL4A1 COL4A3 COL4A4

4.36e-08929310880400
Pubmed

Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.

COL4A1 COL4A3 COL4A4

4.36e-0892938995276
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A1 COL4A3 COL4A4

6.23e-08102939136074
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

COL4A1 COL4A3 COL4A4

6.23e-08102939415455
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

PCF11 ZNF512B BCL9L CHD7 KMT2D WDR33

8.10e-0826829633640491
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A1 COL4A3 COL4A4

8.56e-081129314998921
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A1 COL4A3 COL4A4

8.56e-08112937500359
Pubmed

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.

COL4A1 COL4A3 COL4A4

8.56e-08112939731539
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

COL4A1 COL4A3 COL6A5 COL11A2 COL28A1

9.01e-0813529528675934
Pubmed

Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.

COL4A1 COL4A3 COL4A4

1.14e-07122938918877
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A1 COL4A3 COL4A4

1.14e-071229315837576
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A1 COL4A3 COL4A4

1.14e-071229312180907
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A1 COL4A3 COL4A4

1.14e-071229316024816
Pubmed

Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.

COL4A1 COL4A3 COL4A4

1.48e-07132939833687
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL4A1 COL4A3 COL4A4 COL25A1 COL28A1

1.68e-0715329525037231
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A1 COL4A3 COL4A4

1.89e-071429312878203
Pubmed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

COL4A1 COL4A3 COL6A5 COL11A2

2.10e-076229428344315
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

COL4A1 COL4A3 COL4A4

2.36e-071529310625553
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

COL4A1 COL4A3 COL4A4

2.36e-07152939264260
Pubmed

Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.

COL4A1 COL4A3 COL4A4

2.36e-071529310706142
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A1 COL4A3 COL4A4

2.90e-071629315878328
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF512B BCL9L CHD7 KMT2D EP300 SS18L1

3.95e-0735129638297188
Pubmed

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.

COL4A1 COL4A3 COL4A4

4.22e-07182939160753
Pubmed

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.

COL4A1 COL4A3 COL4A4

5.01e-071929315689378
Pubmed

COL4A3/COL4A4 mutations and features in individuals with autosomal recessive Alport syndrome.

COL4A3 COL4A4

6.71e-07229224052634
Pubmed

Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.

CLCNKA CLCNKB

6.71e-0722928544406
Pubmed

Clinico-pathological correlations in 127 patients in 11 large pedigrees, segregating one of three heterozygous mutations in the COL4A3/ COL4A4 genes associated with familial haematuria and significant late progression to proteinuria and chronic kidney disease from focal segmental glomerulosclerosis.

COL4A3 COL4A4

6.71e-07229219357112
Pubmed

Type-IV collagen related diseases.

COL4A3 COL4A4

6.71e-07229212768082
Pubmed

CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions.

CHD7 KMT2D

6.71e-07229228475860
Pubmed

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.

CLCNKA CLCNKB

6.71e-07229227335120
Pubmed

WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription.

PCF11 WNK1

6.71e-07229229196535
Pubmed

Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.

COL4A3 COL4A4

6.71e-07229225229338
Pubmed

Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.

CLCNKA CLCNKB

6.71e-0722928812470
Pubmed

COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy.

COL4A3 COL4A4

6.71e-07229217942953
Pubmed

Polymorphisms in COL4A3 and COL4A4 genes associated with keratoconus.

COL4A3 COL4A4

6.71e-07229220029656
Pubmed

Mutation analysis of COL4A3 and COL4A4 genes in a Chinese autosomal-dominant Alport syndrome family.

COL4A3 COL4A4

6.71e-07229228674241
Pubmed

A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.

CLCNKA CLCNKB

6.71e-07229220805576
Pubmed

Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.

CLCNKA CLCNKB

6.71e-07229225919862
Pubmed

Persistent familial hematuria in children and the locus for thin basement membrane nephropathy.

COL4A3 COL4A4

6.71e-07229216235097
Pubmed

Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.

CLCNKA CLCNKB

6.71e-07229224863058
Pubmed

Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

CLCNKA CLCNKB

6.71e-0722929916798
Pubmed

Kidney kinetics and chloride ion pumps.

CLCNKA CLCNKB

6.71e-0722929916791
Pubmed

Two genes, COL4A3 and COL4A4 coding for the human alpha3(IV) and alpha4(IV) collagen chains are arranged head-to-head on chromosome 2q36.

COL4A3 COL4A4

6.71e-0722929537506
Pubmed

Whole exome sequencing reveals novel COL4A3 and COL4A4 mutations and resolves diagnosis in Chinese families with kidney disease.

COL4A3 COL4A4

6.71e-07229225381091
Pubmed

Collagen type IV (alpha3-alpha4) nephropathy: from isolated haematuria to renal failure.

COL4A3 COL4A4

6.71e-07229215280517
Pubmed

Identification of mutations in the alpha 3(IV) and alpha 4(IV) collagen genes in autosomal recessive Alport syndrome.

COL4A3 COL4A4

6.71e-0722927987396
Pubmed

Heterozygous COL4A3/COL4A4 mutations: the hidden part of the iceberg?

COL4A3 COL4A4

6.71e-07229235090027
Pubmed

The genetics of thin basement membrane nephropathy.

COL4A3 COL4A4

6.71e-07229215880327
Pubmed

The COL4A3 and COL4A4 Digenic Mutations in cis Result in Benign Familial Hematuria in a Large Chinese Family.

COL4A3 COL4A4

6.71e-07229229742505
Pubmed

Is there a dominant-negative effect in individuals with heterozygous disease-causing variants in COL4A3/COL4A4?

COL4A3 COL4A4

6.71e-07229238214412
Pubmed

Salt wasting and deafness resulting from mutations in two chloride channels.

CLCNKA CLCNKB

6.71e-07229215044642
Pubmed

Nine novel COL4A3 and COL4A4 mutations and polymorphisms identified in inherited membrane diseases.

COL4A3 COL4A4

6.71e-07229217216251
Pubmed

Heterozygous Urinary Abnormality-Causing Variants of COL4A3 and COL4A4 Affect Severity of Autosomal Recessive Alport Syndrome.

COL4A3 COL4A4

6.71e-07229235369551
Pubmed

Presumed COL4A3/COL4A4 Missense/Synonymous Variants Induce Aberrant Splicing.

COL4A3 COL4A4

6.71e-07229235386907
Pubmed

COL4A3/COL4A4 mutations: from familial hematuria to autosomal-dominant or recessive Alport syndrome.

COL4A3 COL4A4

6.71e-07229212028435
Pubmed

Polymorphism analysis of COL4A3 and COL4A4 genes in Greek patients with keratoconus.

COL4A3 COL4A4

6.71e-07229225083577
Pubmed

Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly.

COL4A3 COL4A4

6.71e-07229220847057
Pubmed

Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.

CLCNKA CLCNKB

6.71e-07229238069401
Pubmed

Collagen type IV-related nephropathies in Portugal: pathogenic COL4A3 and COL4A4 mutations and clinical characterization of 25 families.

COL4A3 COL4A4

6.71e-07229225307543
Pubmed

Two highly homologous members of the ClC chloride channel family in both rat and human kidney.

CLCNKA CLCNKB

6.71e-0722928041726
Pubmed

COL4A3/COL4A4 mutations link familial hematuria and focal segmental glomerulosclerosis. glomerular epithelium destruction via basement membrane thinning?

COL4A3 COL4A4

6.71e-07229218661361
Pubmed

Genetic, Clinical, and Pathologic Backgrounds of Patients with Autosomal Dominant Alport Syndrome.

COL4A3 COL4A4

6.71e-07229227281700
Pubmed

[From Alport syndrome to benign familial hematuria: clinical and genetic aspect].

COL4A3 COL4A4

6.71e-07229216895672
Pubmed

How to resolve confusion in the clinical setting for the diagnosis of heterozygous COL4A3 or COL4A4 gene variants? Discussion and suggestions from nephrologists.

COL4A3 COL4A4

6.71e-07229232232700
Pubmed

A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.

CLCNKA CLCNKB

6.71e-07229218648499
Pubmed

Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.

CLCNKA CLCNKB

6.71e-07229211014860
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

COL4A1 COL4A3 COL4A4

6.86e-072129327856617
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

PCF11 BCL9L EP300 CSTF2T SEC23A PCLO

1.20e-0642529624999758
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

COL4A1 COL4A3 COL4A4

1.34e-062629324742657
InteractionSP7 interactions

PCF11 BCL9L CHD7 KMT2D WDR33 EP300 SS18L1

1.50e-07304287int:SP7
InteractionDCN interactions

COL4A1 COL4A3 COL4A4 SFTPD

3.54e-0743284int:DCN
InteractionSAA1 interactions

COL4A1 COL4A3 COL4A4 WDR33

8.99e-0754284int:SAA1
InteractionCRX interactions

ZNF512B BCL9L CHD7 KMT2D EP300 SS18L1

1.13e-06254286int:CRX
InteractionELF5 interactions

ZNF512B CHD7 KMT2D EP300 SS18L1

1.66e-06147285int:ELF5
InteractionHABP2 interactions

COL4A1 COL4A3 COL4A4

1.93e-0618283int:HABP2
InteractionOSM interactions

COL4A1 COL4A3 COL4A4

2.70e-0620283int:OSM
InteractionEGR2 interactions

BCL9L CHD7 KMT2D EP300 SS18L1

3.48e-06171285int:EGR2
InteractionLHX3 interactions

ZNF512B CHD7 KMT2D CLCNKA SS18L1

5.11e-06185285int:LHX3
InteractionTGFBI interactions

COL4A1 COL4A3 COL4A4

5.41e-0625283int:TGFBI
InteractionFEV interactions

ZNF512B CHD7 KMT2D EP300 SS18L1

8.03e-06203285int:FEV
InteractionPAX8 interactions

CHD7 KMT2D EP300 SS18L1

1.61e-05111284int:PAX8
InteractionSUPT5H interactions

PCF11 ZNF512B CHD7 KMT2D WDR33 EP300

1.71e-05408286int:SUPT5H
InteractionTBR1 interactions

BCL9L CHD7 KMT2D EP300

1.73e-05113284int:TBR1
InteractionSMAD1 interactions

ZNF512B COL4A1 KMT2D EP300 SS18L1

1.92e-05243285int:SMAD1
InteractionTBXT interactions

CHD7 KMT2D EP300 SS18L1

1.92e-05116284int:TBXT
InteractionPAX7 interactions

CHD7 KMT2D EP300 SS18L1

2.49e-05124284int:PAX7
InteractionPAX9 interactions

BCL9L CHD7 KMT2D EP300

3.00e-05130284int:PAX9
InteractionCD93 interactions

COL4A1 COL4A3 COL4A4

3.28e-0545283int:CD93
InteractionCPSF3 interactions

PCF11 WDR33 EP300 CSTF2T

4.73e-05146284int:CPSF3
InteractionSERPINE2 interactions

COL4A1 COL4A3 COL4A4

6.34e-0556283int:SERPINE2
InteractionCSTF2 interactions

PCF11 WDR33 CSTF2T SS18L1

7.61e-05165284int:CSTF2
InteractionFBLN2 interactions

COL4A1 COL4A3 COL4A4

1.04e-0466283int:FBLN2
InteractionMMP9 interactions

COL4A1 COL4A3 COL4A4

1.08e-0467283int:MMP9
InteractionALG13 interactions

PCF11 KMT2D WDR33 EP300

1.14e-04183284int:ALG13
InteractionLHX2 interactions

ZNF512B BCL9L CHD7 KMT2D

1.14e-04183284int:LHX2
InteractionDUXA interactions

ZNF512B CHD7

1.22e-0412282int:DUXA
InteractionGATA3 interactions

PCF11 CHD7 KMT2D EP300

1.23e-04187284int:GATA3
InteractionPAX6 interactions

ZNF512B CHD7 KMT2D EP300 SS18L1

1.34e-04366285int:PAX6
InteractionPCAT1 interactions

EP300 PCLO

1.93e-0415282int:PCAT1
InteractionSOX7 interactions

CHD7 KMT2D EP300

1.98e-0482283int:SOX7
InteractionIRF4 interactions

CHD7 KMT2D EP300

2.20e-0485283int:IRF4
InteractionGSC interactions

BCL9L KMT2D EP300

2.35e-0487283int:GSC
InteractionHMGN2 interactions

PCF11 WNK1 EP300 PCLO

2.38e-04222284int:HMGN2
InteractionERG interactions

CHD7 KMT2D EP300 SS18L1

2.43e-04223284int:ERG
InteractionFIP1L1 interactions

PCF11 WDR33 EP300 CSTF2T

2.51e-04225284int:FIP1L1
InteractionNUP35 interactions

PCF11 BCL9L KMT2D WDR33 EP300

2.65e-04424285int:NUP35
InteractionFOXI1 interactions

KMT2D EP300 CSTF2T

2.78e-0492283int:FOXI1
InteractionSOX10 interactions

CHD7 KMT2D EP300

2.78e-0492283int:SOX10
InteractionSOX9 interactions

CHD7 KMT2D EP300

3.24e-0497283int:SOX9
InteractionAR interactions

PCF11 ZNF512B BCL9L CHD7 KMT2D WDR33 EP300

3.27e-04992287int:AR
InteractionASF1A interactions

ZNF512B CHD7 KMT2D EP300

3.69e-04249284int:ASF1A
InteractionLHX1 interactions

ZNF512B CHD7 KMT2D

3.87e-04103283int:LHX1
InteractionAJUBA interactions

ZNF512B IQCN EP300

3.87e-04103283int:AJUBA
InteractionCPSF1 interactions

PCF11 WDR33 EP300 CSTF2T

4.04e-04255284int:CPSF1
InteractionWDR59 interactions

IQCN D2HGDH EP300

4.57e-04109283int:WDR59
InteractionNUDT16 interactions

COL20A1 D2HGDH

4.63e-0423282int:NUDT16
InteractionEN1 interactions

CHD7 KMT2D EP300

4.69e-04110283int:EN1
InteractionCEP170P1 interactions

PCF11 WDR33 CSTF2T

5.08e-04113283int:CEP170P1
InteractionMIA2 interactions

COL20A1 SEC23A SS18L1

5.08e-04113283int:MIA2
InteractionMATN2 interactions

COL4A1 COL4A3 COL4A4

5.08e-04113283int:MATN2
InteractionHNF4A interactions

CHD7 KMT2D EP300 SS18L1

5.37e-04275284int:HNF4A
InteractionETS1 interactions

KMT2D EP300 SS18L1

6.20e-04121283int:ETS1
InteractionRBBP5 interactions

CHD7 KMT2D WDR33 EP300

6.30e-04287284int:RBBP5
InteractionTLX3 interactions

BCL9L CHD7 KMT2D EP300

6.63e-04291284int:TLX3
InteractionPLOD1 interactions

COL4A1 COL4A4 COL25A1 EP300

6.72e-04292284int:PLOD1
InteractionANTXR2 interactions

COL4A3 COL4A4

7.38e-0429282int:ANTXR2
InteractionMYB interactions

CHD7 KMT2D EP300

8.16e-04133283int:MYB
InteractionSPATA1 interactions

WNK1 EP300

8.44e-0431282int:SPATA1
InteractionETV5 interactions

KMT2D EP300

9.57e-0433282int:ETV5
InteractionDTX2 interactions

PCF11 BCL9L WDR33 SEC23A

1.06e-03330284int:DTX2
InteractionE2F5 interactions

KMT2D EP300

1.14e-0336282int:E2F5
InteractionHOXB2 interactions

KMT2D EP300

1.14e-0336282int:HOXB2
InteractionOXSR1 interactions

WNK1 D2HGDH EP300

1.27e-03155283int:OXSR1
Cytoband1p36

CLCNKA CLCNKB

4.09e-04472921p36
Cytoband20q13.33

ZNF512B COL20A1

1.15e-037929220q13.33
CytobandEnsembl 112 genes in cytogenetic band chr2q36

COL4A3 COL4A4

1.33e-0385292chr2q36
CytobandEnsembl 112 genes in cytogenetic band chr20q13

ZNF512B COL20A1 SS18L1

2.36e-03422293chr20q13
Cytoband6p21.3

COL11A2 HCP5

1.09e-022502926p21.3
GeneFamilyCollagens

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

1.14e-1646208490
GeneFamilyChloride voltage-gated channels

CLCNKA CLCNKB

5.20e-0510202302
CoexpressionNABA_COLLAGENS

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

1.10e-1643298MM17060
CoexpressionNABA_COLLAGENS

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

1.34e-1644298M3005
CoexpressionNABA_CORE_MATRISOME

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

4.07e-10270298MM17057
CoexpressionNABA_CORE_MATRISOME

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 COL20A1 COL28A1

4.70e-10275298M5884
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A1 COL4A3 COL4A4 COL6A5

1.07e-0740294M5887
CoexpressionNABA_MATRISOME

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 SFTPD COL20A1 COL28A1

8.88e-071008299MM17056
CoexpressionNABA_MATRISOME

COL4A1 COL4A3 COL4A4 COL6A5 COL11A2 COL25A1 SFTPD COL20A1 COL28A1

1.03e-061026299M5889
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

COL4A1 COL4A3 COL4A4

2.12e-0623293M48001
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_AT1_CELL

COL4A3 COL4A4 SFTPD

1.36e-0542293M45688
CoexpressionGSE31082_DN_VS_CD8_SP_THYMOCYTE_DN

CHD7 KMT2D CLCNKA WNK1

6.73e-05200294M5063
CoexpressionDESCARTES_FETAL_PANCREAS_ENS_GLIA

COL25A1 COL20A1 COL28A1

7.79e-0575293M40269
CoexpressionNABA_MATRISOME_HIGHLY_METASTATIC_MELANOMA

COL11A2 COL28A1

1.79e-0418292M47984
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A3 COL4A4 IQCN PCLO

1.16e-071832956821dca076318115d360ff426eb1218cfe104063
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 CLCNKA CLCNKB WNK1

1.36e-0718929555420853f730b433ef58ac9337ac84ac78a247a0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 CLCNKA CLCNKB WNK1

1.59e-07195295a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 CLCNKA CLCNKB WNK1

1.63e-07196295f40d10ea7714067585493fdc89744714aa427de8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 CLCNKA CLCNKB WNK1

1.63e-07196295b8350340d86e4524e9616a427e7f2e116a6fb3be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 CLCNKA CLCNKB WNK1

1.71e-07198295688b0eb5534dde40b8630ab8a3252c816711e02e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 CLCNKB WNK1

3.09e-061562944d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A3 COL4A4 CLCNKB

3.59e-0616229457d627259d27f39885bf416d74bcb6656db6e27b
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL25A1 SFTPD COL20A1 COL28A1

4.14e-06168294948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

4.65e-061732940c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

4.87e-06175294787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 WNK1 GPR75

4.98e-06176294f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CHD7 KMT2D COL25A1 COL20A1

5.09e-061772945357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 CLCNKB WNK1

5.09e-06177294c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 SS18L1 GPR75

5.32e-0617929488dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 SS18L1 GPR75

5.32e-06179294daf8189a22786171e2b629261cf720736aa4ebdb
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 COL25A1 COL20A1 COL28A1

5.94e-06184294226ccac00ac1c3a0ad7283785fd14312320e0ca6
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A3 COL4A4 FGD5

6.20e-0618629490d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A3 COL4A4 FGD5

6.20e-061862942cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

COL4A1 COL4A3 COL4A4 SFTPD

6.20e-06186294df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCellIPF-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

COL4A1 COL4A3 COL4A4 SFTPD

6.20e-06186294d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

6.46e-06188294eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A1 COL4A3 COL4A4 COL25A1

6.46e-061882948268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A3 COL4A4 CLCNKA CLCNKB

6.46e-061882941d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 COL25A1 COL20A1 COL28A1

6.46e-06188294ccd2541892112a7a303f766adf9a7afeb754498c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

6.46e-06188294bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A1 COL4A3 COL4A4 COL25A1

6.46e-061882944544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB COL28A1

6.46e-061882943cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

COL4A3 COL4A4 CLCNKB WNK1

6.46e-06188294df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

6.60e-06189294f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A1 COL4A3 COL4A4 COL25A1

6.74e-061902942f54da2bee411f8868348a4c37034184b8f58a89
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB COL28A1

6.74e-061902943dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

6.74e-06190294b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellPSB-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL4A1 COL4A4 CLCNKA CLCNKB

6.88e-061912948f4637e801554e2343b974fe7794f01dd2151418
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A3 COL4A4 CLCNKB COL28A1

6.88e-06191294fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

7.02e-0619229432e4a180037e516c5cc798cd9dada9385e0f43ae
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB COL28A1

7.02e-06192294562df5e87038c500dd3a003fe5374cb31946b145
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 WNK1 SFTPD

7.17e-0619329454506c0da2f219f472b95e8935a78b657a8dec41
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 WNK1 SFTPD

7.17e-061932942d42721fac1bee294ede47d609bebb3e7d36bf0c
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

7.17e-06193294dd9874898587fe9fd9cf2aebc2e0579dcf06944e
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

7.32e-06194294f08a7618a9ccf12e4a7620235ae662a8abc521af
ToppCelldroplet-Kidney-KIDNEY-1m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A3 COL4A4 CLCNKA

7.32e-06194294837cee7e6147d92a2f4b86f1ed761a9bfe65b61d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

7.47e-0619529460d08fb27469d1e247bc47b651d7023ba82cf92f
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB WNK1

7.47e-061952943123e02d2894c83962ba402085b5e6422ebf8c73
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL4A3 COL4A4 CHD7 SFTPD

7.77e-061972943d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 CLCNKA CLCNKB

7.93e-061982944448d13511485a44fe7b549e4b8b6ad7637db624
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 COL25A1 COL20A1 COL28A1

8.09e-06199294a76aa30fb264bdcbc0cb09113f814fc5a89e7319
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 COL25A1 COL20A1 COL28A1

8.09e-061992945f350d9c7da9ac111bf22623dd4fed7f7983c9fc
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

COL4A1 COL4A3 COL4A4 COL25A1

8.25e-06200294ca5401b76ab014080914bf78042d368cf318effa
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1|Neuronal / cells hierarchy compared to all cells using T-Statistic

COL4A1 COL4A3 COL4A4 COL25A1

8.25e-0620029440286010bd17cf9e34ecd5440953b072ebfae208
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

COL4A3 COL4A4 CHD7 SFTPD

8.25e-062002942dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellKidney|World / Skin and Kidney Cells in Lupus Nephritis Patients.

COL4A1 COL4A4 CLCNKA CLCNKB

8.25e-062002941f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

COL4A1 COL4A3 COL4A4 COL25A1

8.25e-0620029470c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1

2.29e-05852935a2c02aeceeabd44a417b09ac8b2e2f185070b15
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1

2.29e-05852937c5ea38893372fdecf7cc3ccf46a37b4ec45f0b1
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1

2.29e-05852930bfabb6761a84d6a04f9fa415106a33059d78099
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Abcc9_(Mural.Rgs5Acta2.Abcc9)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1

3.96e-0510229372ce247dad7404e6b9c971b5c29d3c6846da5efc
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Abcc9_(Mural.Rgs5Acta2.Abcc9)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1

3.96e-051022938c4d9483ff983538593f4e17f4a74a93cdda59c4
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1

3.96e-051022935feedce6d26a578c4aaba4e4824b3d0c3f3806bc
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1

5.37e-051132930651fb7a7e1ea84b8365059e5ed85bf6c082da1a
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8-MURAL_Mural.Acta2Rgs5.Kcnj8-Abcc9_(Mural.Acta2Rgs5.Kcnj8-Abcc9)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL4A3 COL4A4 COL28A1

5.37e-051132930e153efddd061d7510dfc3859cc8b1a7984fa70e
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|E18.5-samps / Age Group, Lineage, Cell class and subclass

COL4A3 COL4A4 WNK1

1.06e-0414229377fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCellEpithelial-B_(AT1-AT2-progenitors)|World / shred on cell class and cell subclass (v4)

COL4A3 COL4A4 SFTPD

1.15e-041462934511916904c1fac252cb68e871b782207f8137b3
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(II)|lymph-node_spleen / Manually curated celltypes from each tissue

ZNF512B COL4A4 QRICH2

1.30e-041522934f690aed23338687bdefc47e8a2f3d1fdb2b6447
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 CLCNKA CLCNKB

1.32e-041532930307f10e772021ae68a42690634df458672a6df9
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A3 COL4A4

1.37e-04155293010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellcellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL11A2 CLCNKA CLCNKB

1.51e-041602939049707a4487f2337a17976ceb5fbd8815ab9e1d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A1 COL4A3 COL4A4

1.51e-0416029358ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellcellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL11A2 CLCNKA CLCNKB

1.51e-04160293f2cfec54cf48a655f473b830be7d141c54b521ff
ToppCellIPF-Epithelial-Ionocyte|IPF / Disease state, Lineage and Cell class

CLCNKA CLCNKB PCLO

1.51e-04160293d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCellcellseq2-Epithelial-Epithelial_Neuro-Secretory|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL11A2 CLCNKA CLCNKB

1.51e-041602930eb50b3c494e1b65d40104b3b5411b57bb72b959
ToppCellIPF-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

CLCNKA CLCNKB PCLO

1.53e-04161293f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

COL4A1 COL4A4 SFTPD

1.53e-041612931973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 SFTPD

1.56e-04162293d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A4 COL25A1

1.56e-041622935f009b231f21861afee9cc0c569082e1135f929c
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 SFTPD

1.56e-0416229306f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A3 COL4A4

1.56e-04162293ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellControl-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

CLCNKA CLCNKB PCLO

1.56e-04162293e3b9b46ce2faff7d099502df14bbf51e9f183f8c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A4 COL25A1

1.56e-04162293b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCellControl-Epithelial-Ionocyte|Control / Disease state, Lineage and Cell class

CLCNKA CLCNKB PCLO

1.59e-04163293bf09fa39bf3e6b3a776d5e79c30c96df572956a3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 COL25A1 COL20A1

1.62e-0416429357301178e420983c0cb72178e288a3a0449fdda3
ToppCellInfluenza_Severe-B_memory|Influenza_Severe / Disease group and Cell class

COL4A3 COL4A4 CHD7

1.65e-0416529351172acaeb667b34b8b8c7878d67cfa0c4a2dffc
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A3 COL4A4 GPR75

1.71e-041672939f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL11A2 COL25A1 GPR75

1.71e-04167293102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 COL25A1 COL20A1

1.71e-0416729317c653b46507c8bb85da95836ae72a6015336142
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A3 COL4A4 GPR75

1.71e-04167293bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 COL20A1 COL28A1

1.74e-04168293af82e07d1eec51fc6530155f37addbce6221885d
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A4 PCLO

1.77e-04169293815474855a70498a74e52f6583113c63b7267a0c
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

COL4A1 COL4A3 COL4A4

1.80e-04170293e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 COL25A1 COL20A1

1.86e-04172293bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCellsevere_influenza-B_memory|World / disease group, cell group and cell class (v2)

COL4A3 COL4A4 CHD7

1.86e-041722930ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 SFTPD

1.90e-0417329345808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A3 COL4A4

1.90e-041732933afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCellP07-Epithelial|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 SFTPD

1.90e-041732938b10087a917b825809d35a2b2b349c73a2782472
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A4 SFTPD

1.90e-041732937fa9dbcb258c3ab974490063951620e2def03db1
ToppCellPCW_13-14-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL25A1 COL20A1 COL28A1

1.93e-041742930d8e737860120dcd3a6b57992c612595904d585e
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 COL4A4 SFTPD

1.93e-04174293edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3-6_VIP_KCTD13|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A3 FGD5 CHD7

1.93e-0417429362f5dc7086e1491fc90f005ccadfa1b772b52fad
ToppCellP07-Epithelial-alveolar_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 SFTPD

1.93e-041742932739de68e0266054694f99807cfb1f07b6bbb371
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A3 COL4A4 SFTPD

1.93e-041742932cd6638b361ca05ab83d09ce657194aed97873b7
DrugGK-101

COL4A1 COL4A3 COL11A2 COL25A1

1.22e-0736294CID000161853
Drughydroxylysine

COL4A1 COL4A3 COL11A2 COL25A1 SFTPD

2.48e-07109295CID000001029
DrugMadecassol

COL4A1 COL4A3 COL11A2 COL25A1

3.34e-0746294CID000108062
Drugd-indobufen

COL4A1 COL4A3 COL11A2 COL25A1

4.69e-0750294CID000044562
Drugridogrel

COL4A1 COL4A3 COL11A2 COL25A1

5.51e-0752294CID005362391
DrugNSC49633

COL4A1 COL4A3 COL11A2 COL25A1

5.95e-0753294CID000023340
DrugAC1LAKND

COL4A1 COL4A3 COL11A2 COL25A1

1.12e-0662294CID000470146
DrugBAPN

COL4A1 COL4A3 COL11A2 COL25A1

1.94e-0671294CID000001647
Drugmalotilate

COL4A1 COL4A3 COL11A2 COL25A1

1.94e-0671294CID000004006
DrugAC1NMZ1B

COL4A1 COL4A3 COL11A2 COL25A1

2.42e-0675294CID005034185
Drugstrontium ranelate

COL4A1 COL4A3 COL11A2 COL25A1

2.69e-0677294CID006918182
Drughalofuginone lactate

COL4A1 COL4A3 COL11A2 COL25A1

4.00e-0685294CID000062891
Drug4-hydroxyproline

COL4A1 COL4A3 COL11A2 COL25A1

5.25e-0691294CID000000825
Drugticlopidine

COL4A1 COL4A3 COL11A2 COL25A1

8.60e-06103294CID000005472
DrugAC1L1C2F

COL4A1 COL4A3 COL11A2 COL25A1

1.12e-05110294CID000001711
DrugPPACK

COL4A1 COL4A3 COL11A2 COL25A1

1.24e-05113294CID003036757
DrugAC1L9732

COL4A1 COL4A3 COL11A2 COL25A1

1.29e-05114294CID000439300
DrugTranilast sodium

COL4A1 COL4A3 COL11A2 COL25A1

1.33e-05115294CID000005527
Drug2-Methyl-4-chlorophenoxyacetic Acid

CLCNKA CLCNKB

1.56e-055292ctd:D008456
DrugSelara

COL4A1 COL4A3 COL11A2 COL25A1

1.85e-05125294CID000150310
DrugDMSe

COL4A1 COL4A3 COL11A2 COL25A1

2.29e-05132294CID000020796
Drugpirfenidone

COL4A1 COL4A3 COL11A2 COL25A1

2.73e-05138294CID000040632
DrugDL-penicillamine

COL4A1 COL4A3 COL11A2 COL25A1

2.81e-05139294CID000004727
DrugPCR 4099

COL4A1 COL4A3 COL11A2 COL25A1

2.81e-05139294CID000002806
Drugcandesartan cilexetil

COL4A1 COL4A3 COL11A2 COL25A1

3.31e-05145294CID000002540
Drug(2s,5s)-5-Carboxymethylproline

COL4A1 COL4A3 COL11A2 COL25A1 SFTPD

4.37e-05314295CID000447989
DrugL-lysyl-L-lysyl-L-lysine

COL4A1 COL4A3 COL11A2 COL25A1

5.11e-05162294CID000072363
Drugkhellin

COL4A1 COL4A3 COL11A2 COL25A1

6.30e-05171294CID000003828
DrugAC1L1DD6

COL4A1 COL4A3 COL11A2 COL25A1

7.52e-05179294CID000002299
Drug12(S)-hydroxyeicosatetraenoic acid

COL4A1 COL4A3 COL11A2 COL25A1

9.29e-05189294CID000001413
Drugfoscarnet

COL4A1 COL4A3 COL11A2 COL25A1

9.48e-05190294CID000003414
DrugParbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A

WNK1 WDR33 CSTF2T PCLO

1.07e-041962943881_DN
DrugSTOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A

ZNF512B CHD7 WNK1 SEC23A

1.09e-041972946561_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A

ZNF512B WNK1 EP300 CSTF2T

1.09e-041972941640_DN
DrugTetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A

COL4A1 COL4A3 COL4A4 GPR75

1.13e-041992946069_UP
Drugcalcium pyrophosphate

COL11A2 CLCNKA CLCNKB

1.13e-0474293CID000024632
DrugAC1L8Y60

CLCNKA CLCNKB WNK1

1.96e-0489293CID000410009
DrugAC1Q6PCP

COL4A1 COL4A3 COL11A2 COL25A1

1.98e-04230294CID000005267
Drugprostacyclin sodium salt

COL4A1 COL4A3 COL11A2 COL25A1

2.72e-04250294CID000000159
DrugPtdIns(4)P

COL4A3 SFTPD COL20A1

3.10e-04104293CID000643965
Drughyaluronan

COL4A1 COL4A3 COL11A2 COL25A1

3.29e-04263294CID000024759
Drugsilibinin

COL4A1 COL4A3 COL11A2 COL25A1

4.46e-04285294CID000005213
DrugLS-63783

COL4A1 COL4A3 COL11A2 COL25A1 CLCNKA CLCNKB

4.51e-04804296CID000000231
Diseasemyopathy (implicated_via_orthology)

COL4A1 COL4A3 COL4A4 CLCNKA CLCNKB

7.22e-1048275DOID:423 (implicated_via_orthology)
Diseasecollagen disease (implicated_via_orthology)

COL4A1 COL4A3 COL4A4

1.49e-0712273DOID:854 (implicated_via_orthology)
DiseaseBartter disease type 3 (implicated_via_orthology)

CLCNKA CLCNKB

8.06e-072272DOID:0110144 (implicated_via_orthology)
DiseaseBartter disease type 4b (is_implicated_in)

CLCNKA CLCNKB

8.06e-072272DOID:0110146 (is_implicated_in)
DiseaseBartter disease type 4B

CLCNKA CLCNKB

8.06e-072272cv:C4310805
DiseaseALPORT SYNDROME 2, AUTOSOMAL RECESSIVE

COL4A3 COL4A4

8.06e-072272C4746745
Diseasebenign familial hematuria (is_implicated_in)

COL4A3 COL4A4

8.06e-072272DOID:0111365 (is_implicated_in)
Diseaseautosomal recessive Alport syndrome (is_implicated_in)

COL4A3 COL4A4

8.06e-072272DOID:0110033 (is_implicated_in)
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

8.06e-072272613090
DiseaseAlport syndrome, recessive type

COL4A3 COL4A4

8.06e-072272C2931254
DiseaseAlport syndrome, dominant type

COL4A3 COL4A4

8.06e-072272C2931253
DiseaseThin basement membrane disease

COL4A3 COL4A4

8.06e-072272C0403440
DiseaseBenign familial hematuria

COL4A3 COL4A4

8.06e-072272cv:C0241908
DiseaseBartter disease (implicated_via_orthology)

CLCNKA CLCNKB

8.06e-072272DOID:445 (implicated_via_orthology)
DiseaseBARTTER SYNDROME, TYPE 4B

CLCNKA CLCNKB

8.06e-072272C2751312
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

8.06e-072272C4310805
DiseaseAlport syndrome

COL4A3 COL4A4

2.42e-063272cv:C1567741
Diseaseautosomal recessive Alport syndrome (implicated_via_orthology)

COL4A3 COL4A4

2.42e-063272DOID:0110033 (implicated_via_orthology)
DiseaseCollagen IV-related nephropathies

COL4A3 COL4A4

2.42e-063272cv:CN076135
DiseaseHematuria, Benign Familial

COL4A3 COL4A4

4.83e-064272C0241908
DiseaseAlport Syndrome

COL4A3 COL4A4

4.83e-064272C1567741
DiseaseAlport Syndrome, X-Linked

COL4A3 COL4A4

8.05e-065272C1567742
DiseaseAlport Syndrome, Autosomal Dominant

COL4A3 COL4A4

8.05e-065272C1567743
DiseaseAlport Syndrome, Autosomal Recessive

COL4A3 COL4A4

8.05e-065272C1567744
Diseasehypertensive nephropathy

COL4A3 COL4A4

1.21e-056272C0848548
DiseaseBartter syndrome

CLCNKA CLCNKB

1.21e-056272cv:C0004775
Diseasenephrogenic diabetes insipidus (implicated_via_orthology)

CLCNKA CLCNKB

3.61e-0510272DOID:12387 (implicated_via_orthology)
Diseasealbuminuria

COL4A3 COL4A4 CHD7

8.66e-0594273EFO_0004285
DiseaseT-Cell Lymphoma

KMT2D EP300

9.60e-0516272C0079772
DiseaseRenal glomerular disease

COL4A3 COL4A4

2.02e-0423272C0268731
DiseaseGlomerulopathy Assessment

COL4A3 COL4A4

2.02e-0423272C4521256
DiseaseHereditary hearing loss and deafness

COL4A3 COL4A4 COL11A2

3.18e-04146273cv:C0236038
DiseaseCongenital small ears

CHD7 KMT2D

6.47e-0441272C0152423
Diseaseend stage renal disease (is_implicated_in)

COL4A3 COL4A4

6.47e-0441272DOID:783 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
EPLQQGSPQMGGQTG

EP300

221

Q09472
GSPQMGGQTGLRGPQ

EP300

226

Q09472
QQQQQGAGPGIGPGM

EP300

2191

Q09472
GAGPGIGPGMANHNQ

EP300

2196

Q09472
QGEPGLQGTQGVPGA

COL4A3

621

Q01955
QMGDPGEVGQQGSPG

COL4A4

241

P53420
PQVPHGGSGGGQMGV

CHD7

111

Q9P2D1
LQGVIGFPGMQGPEG

COL4A1

56

P02462
VQPGAGQLGMVQPGI

QRICH2

736

Q9H0J4
VQGMGQGTEGPGAVS

IQCN

1081

Q9H0B3
MGQNGQEPVKQPGVG

PCLO

4981

Q9Y6V0
QGSPGIPGMDGEQGL

COL25A1

466

Q9BXS0
VMGVGLPGQAAPGEG

FGD5

431

Q6ZNL6
VVGPQGAAGETGPMG

COL11A2

926

P13942
PFMGVPVQGGGDPIQ

GPR75

251

O95800
LTLTMGQGEPGGPQG

HCP5

46

Q6MZN7
QQGGGMRFEGPSVPG

PCF11

1001

O94913
MGIPGIGSQGEQGIQ

COL28A1

446

Q2UY09
IGSQGEQGIQGPIGP

COL28A1

451

Q2UY09
GEPGAVGQMGSPGQQ

COL20A1

1261

Q9P218
SQGQKGPQGSPGLMG

COL6A5

1601

A8TX70
GRTGVPPQQGMVPHG

BCL9L

1401

Q86UU0
MTGGIQGPGPINIGA

CSTF2T

471

Q9H0L4
PGISGVGNPGAGMQG

CSTF2T

496

Q9H0L4
VGNPGAGMQGTGIQG

CSTF2T

501

Q9H0L4
VNPQGGNTGMVGGSV

D2HGDH

126

Q8N465
GGPATQGPGMVVGDE

SEC23A

291

Q15436
GIVTGGVTNPIMPGG

CLCNKA

451

P51800
GIVAGGITNPIMPGG

CLCNKB

451

P51801
GPASQGVPMQGQGTI

SS18L1

156

O75177
AAGQAGMPGQAGPVG

SFTPD

71

P35247
GMPVVRGGQTVPGQA

ZNF512B

41

Q96KM6
PMGGVGGQVQVSQPG

WNK1

1006

Q9H4A3
QGSSGPQGHMGPQGP

WDR33

696

Q9C0J8
QGHLGPQGPPGTQGM

WDR33

726

Q9C0J8
GTQGMQGPPGPRGMQ

WDR33

736

Q9C0J8
SGQGLPGVGIMPTVG

KMT2D

4181

O14686